Academic literature on the topic 'JNC 8 Guidelines'

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Journal articles on the topic "JNC 8 Guidelines"

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Mancia, Giuseppe. "Strengths and limitations of the JNC 8 hypertension guidelines." Nature Reviews Cardiology 11, no. 4 (February 11, 2014): 189–90. http://dx.doi.org/10.1038/nrcardio.2014.12.

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Thomas, Riny, Sini Sam, P. Neelaphar, P. Shabeeb, and B. A. Vishwanath. "A Study on Prescribing Pattern of Antihypertensive in Chronic Kidney Disease Patients." Journal of Drug Delivery and Therapeutics 10, no. 3-s (June 15, 2020): 75–81. http://dx.doi.org/10.22270/jddt.v10i3-s.4139.

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Background: Chronic kidney disease causes progressive loss of function which gradually occur overtime leading to decrease in GFR levels leading to dysfunction of renal system. Hypertension is found to be intermingled cause and overlapping complication in CKD. It is important to intervene the progression by controlling the blood pressure to prevent kidney failure by administration of anti-hypertensive. Objectives: To study current trends in anti-hypertensive prescription pattern in CKD patient and to evaluate the concurrent patterns are in adherence according to the guidelines mentioned. Methods: Prospective observational study was undertaken in patients who were satisfying the inclusion criteria and was enrolled into the study conducted for a 6months period in a tertiary care hospital in Bangalore. Results: 150 CKD patients were examined out of which 72% prevalence seen in males compared to females 28%. Dual drug therapy was most preferred combination seen in 48% of the prescriptions. CCB was the most preferred class of drug and least preferred class of drug was ACE. More than 85% deviation from JNC-8 was seen. 20% of mono-therapy was found in adherence to JNC-8. Conclusion: A 15% adherence to JNC-8 guidelines was observed in the treatment indicating need for clinical pharmacist who play vital role in management of CKD by adherence to JNC-8 to ensure safety, efficacy and rationality. Keywords: Chronic kidney disease, Hypertension, Prescription pattern, JNC-8 guidelines, Compliance, Anti-Hypertensive.
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Varakantham, Varsha, Ashok Kumar Kurakula Sailoo, and Dinesh Kumar Bharatraj. "Antihypertensive Prescription Pattern and Compliance to JNC 7 and JNC 8 at Tertiary Care Government Hospital, Hyderabad, India: A Cross-sectional Retrospective Study." Hospital Pharmacy 53, no. 2 (November 1, 2017): 107–12. http://dx.doi.org/10.1177/0018578717738080.

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Background: The monitoring of hypertension treatment can provide insight into the rational drug use pattern. The objective of this study was to examine the antihypertensive medication use among South Indian adults with hypertension in compliance with the hypertension treatment guidelines (Seventh Joint National Committee [JNC 7] and JNC 8). Methods and Results: A total of 550 hypertensive people aged >25 years were included in this retrospective cross-sectional study. The order of drugs prescribed in the year 2012 was beta blockers (BB) > calcium channel blockers (CCB) > CCB + BB > angiotensin receptor blockers (ARB) > angiotensin-converting enzyme inhibitors (ACEI) > thiazide diuretics, whereas in the year 2014, the order has changed drastically, namely, ACEI > CCB > ARB > BB > thiazide diuretics ( P < .001). Most notably, there was a large increase in the use of monotherapy (from 56.9% to 82.5%, P < .001). The usage of BB has simply moved from the first position to the last position in concordance with JNC 8 guidelines, whereas use of thiazide diuretics was found to be the least preferred drug in the 2012 prescriptions, thus deviating from JNC 7 guidelines. The use of generic names (28.3% vs 11.3%) and National List of Essential Medicines (NLEM) compliance (79.3% vs 60.9%) were significantly more in the calendar year 2012 than in the calendar year 2014 ( P < .001). Conclusions: Antihypertensive medication use has gone through wide variations among south Indian adults with hypertension. Combination therapy regimens must be adopted as per the guidelines for achievement of blood pressure goals.
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Myers, Martin G., and Sheldon W. Tobe. "A Canadian Perspective on the Eighth Joint National Committee (JNC 8) Hypertension Guidelines." Journal of Clinical Hypertension 16, no. 4 (March 19, 2014): 246–48. http://dx.doi.org/10.1111/jch.12307.

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Verma, Vikash, Mukesh Kumar, Arvind Gupta, Kavita Dhar, and Jyotshana Sharma. "A study on drug utilization pattern of antihypertensive drugs in hypertensive diabetic patients." International Journal of Basic & Clinical Pharmacology 8, no. 10 (September 25, 2019): 2242. http://dx.doi.org/10.18203/2319-2003.ijbcp20194264.

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Background: Hypertension management is of paramount importance in diabetic patients for reduction of cardiovascular and other complications. The objective of the present study was to assess prescribing pattern of antihypertensive drugs in hypertensive type 2 diabetic patients and evaluate them by comparing with Eighth Joint National Committee (JNC-8) hypertension treatment guidelines.Methods: A prospective observational study was carried out on 110 hypertensive type 2 diabetic patients of age 41-80 years visiting outpatient department of Medicine at G.S. Medical College and Hospital, UP, India for 4 months. JNC-8 hypertension management guideline was considered while evaluating the prescribed drugs. All the relevant data was collected from the prescription card of the patient on a preformed performa and analyzed using descriptive statistics.Results: Total of 176 drugs was prescribed to the study patients among which two drug combination therapy (55.45%) was mostly used. The most common group prescribed was angiotensin receptor blocker (ARB) (29.45%) and ARB+CCB (calcium channel blockers) (34.92%) were the commonest fixed drug combination. Overall, it was amlodipine (21.47%) that was most frequently prescribed among all antihypertensive drugs.Conclusions: ARB was the most commonest class, ARB+CCB was the most frequent fixed drug combination prescribed to the study patient while amlodipine was the highly utilized individual antihypertensive drug in the study. Prescriptions evaluation revealed that 94.88% prescription were rational and were in accordance with the JNC-8 hypertension treatment guidelines except the use of beta blockers (5.12%).
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Goldstein, Felicia C., Ihab M. Hajjar, Callie B. Dunn, Allan I. Levey, and Whitney Wharton. "The Relationship Between Cognitive Functioning and the JNC-8 Guidelines for Hypertension in Older Adults." Journals of Gerontology Series A: Biological Sciences and Medical Sciences 72, no. 1 (September 27, 2016): 121–26. http://dx.doi.org/10.1093/gerona/glw181.

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Raju, Sivasakthi, Sam Solomon, Nithiyan N, Karthik K, Anns Clara Joseph, and Venkatanarayanan V. "Assessment of Prescribing Pattern for Hypertension and Comparison with JNC-8 Guidelines-Proposed Intervention by Clinical Pharmacist." Journal of Young Pharmacists 8, no. 2 (April 1, 2016): 133–35. http://dx.doi.org/10.5530/jyp.2016.2.14.

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Bhore, A. S., Kalyani Khandare, and K. A. Bansod. "Prescription pattern and rationality of antihypertensive drugs in patients of type 2 diabetes with hypertension: a pilot study." International Journal of Research in Medical Sciences 7, no. 4 (March 27, 2019): 982. http://dx.doi.org/10.18203/2320-6012.ijrms20191299.

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Background: As presence of hypertension (HTN) in type 2 diabetes significantly increases risk of morbidity and mortality, its control with rational use of antihypertensives is essential. Authors performed this study to understand the current prescribing pattern of antihypertensives in patients of type 2 diabetes and their assess the rationality to recommendations of JNC-8 guidelines.Methods: Authors performed a cross sectional survey of prescription of diagnosed patients of diabetes with HTN at a tertiary care hospital. Prescription of patients attending medicine OPD were scanned. Data was collected over 2 month and analyzed with descriptive statistics.Results: In 76 patients analysed, mean age was 54.9±9.3 years and 51.3% were females. Insulin and oral antidiabetic agents were prescribed in 16 (21.1%) and 73 (96.1%) patients respectively. One, two, three and four antihypertensive drugs were prescribed in 44 (57.9%), 28 (36.8%), 3 (3.9%) and 1 (1.3%) patients respectively and 24 (31.6%) of them were fixed dose combinations. Among antihypertensives, angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), thiazide diuretics, beta blockers (BBs) and calcium channel blockers (CCBs) were present in 29 (38.2%), 26 (34.2%), 22 (28.9%), 21 (27.6%) and 14 (18.4%) respectively. In individual drugs, ramipril (28.9%) was most common followed by telmisartan (26.3%), hydrochlorothiazide (26.3%), atenolol (16, 21.1%) and amlodipine (17.1%) were frequently prescribed. In adjuvant drugs, antiplatelet (52.6%) and statins (56.6%) were common. This pattern of prescription was as per the recommendations of recent JNC-8 guidelines for treatment of hypertension.Conclusions: ACEIs/ARB are the most preferred for HTN treatment in type 2 diabetes mellitus. Prescription of antihypertensives in our set up was rational as per JNC-8 recommendations.
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Reisin, Efrain, Raymond C. Harris, and Mahboob Rahman. "Commentary on the 2014 BP Guidelines from the Panel Appointed to the Eighth Joint National Committee (JNC 8)." Journal of the American Society of Nephrology 25, no. 11 (August 11, 2014): 2419–24. http://dx.doi.org/10.1681/asn.2014040371.

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Abel, Nicole, Krysta Contino, Navjot Jain, Navjot Grewal, Elizabeth Grand, Iris Hagans, Krystal Hunter, and Satyajeet Roy. "Eighth joint national committee (JNC-8) guidelines and the outpatient management of hypertension in the African-American population." North American Journal of Medical Sciences 7, no. 10 (2015): 438. http://dx.doi.org/10.4103/1947-2714.168669.

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Dissertations / Theses on the topic "JNC 8 Guidelines"

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Goodlow, Tranise Hamilton, and Tranise Hamilton Goodlow. "Provider Adherence to JNC 8 Pharmacological Guideline Recommendations in African American Adults Diagnosed with Hypertension." Diss., The University of Arizona, 2017. http://hdl.handle.net/10150/626646.

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Background: In the United States, one-third of adults have hypertension (HTN). Among African American (AA) adults, 43% of men and 45.7% of women have HTN. HTN in the AA adult population is more severe and occurs earlier in life compared to Caucasian adults, putting them at increased risk for cardiovascular events and renal disease. The Eighth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 8) Guideline Recommendations 7 and 8 were developed to aid in appropriate treatment and management of hypertensive AA adults. Purpose: The purpose of this Doctor of Nursing Practice (DNP) project was to improve the care, management, and outcomes of hypertensive AA adults by identifying current JNC 8 guideline prescribing patterns among a sample of hospitalized patients. The first project aim was to determine provider-prescribing rates of thiazide diuretics (TDs) and calcium channel blockers (CCBs) in newly diagnosed AA adults with HTN. The second project aim was to determine if AA adults previously diagnosed with HTN were currently prescribed TD and/or CCB medications. Methods: A retrospective medical record review of AA adult patients with a new HTN diagnosis or previously diagnosed with HTN was selected for this project. Participants were discharged from Medical City Dallas between 01/01/2017 and 03/31/2017. Results: In newly diagnosed participants with HTN, none were prescribed a TD (0%) and two were prescribed a CCB (40%). In previously diagnosed participants with HTN, 30 participants (16.3%) were prescribed a TD and/or CCB upon admission and 29 participants (15.76%) were prescribed a TD and/or CCB upon discharge. Among prescribing providers, beta blockers and other class hypertensive medications (i.e., furosemide, hydralazine, clonidine, and spironolactone) were most widely ordered for participants. Conclusions: The results of this DNP project display low provider compliance rates to guideline-recommended pharmacological therapy AA adults. This outcome highlights several potential reasons for the low adherence rates, including lack of provider documentation, lack of provider rationale for treatment selections, provider knowledge of HTN CPGs, and data analysis of prescribed medications. These factors present the opportunity for further research to identify the root cause of low compliance.
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Book chapters on the topic "JNC 8 Guidelines"

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Thadani, Udho, and Nguyen Duc Cong. "Hypertension: Implications of Current JNC 8 Guidelines on Treatment." In Management of Complex Cardiovascular Problems, 30–49. Oxford, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118965061.ch2.

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