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1

Materson, Barry J. "JNC 8 Transmogrified." Journal of Clinical Hypertension 15, no. 10 (2013): 704. http://dx.doi.org/10.1111/jch.12174.

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Amsterdam, Ezra A., Sandhya Venugopal, Jonathan Bui, et al. "Management of Hypertension: JNC 8 and Beyond." Cardiovascular Innovations and Applications 1, no. 4 (2016): 409–16. http://dx.doi.org/10.15212/cvia.2016.0030.

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Furberg, C. D., and M. H. Alderman. "JNC 8: Shortcomings in Process and Treatment Recommendations." American Journal of Hypertension 27, no. 12 (2014): 1443–45. http://dx.doi.org/10.1093/ajh/hpu158.

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Anggraini, Truly Dian, Eka Wisnu Kusuma, and Deswinda Diandari. "Pengaruh Rasionalitas Penggunaan Antihipertensi dengan Standart Guideline JNC 8 Terhadap Keberhasilan Terapi Hipertensi di RS Panti Waluyo Surakarta." Jurnal Farmasi (Journal of Pharmacy) 6, no. 1 (2019): 6–9. http://dx.doi.org/10.37013/jf.v6i1.39.

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AbstrackHipertensi merupakan masalah utama kesehatan publik di seluruh dunia dan merupakan faktor resiko penyakit kardiovaskuler tersering. Prevalensi hipertensi pada penduduk umur 18 tahun ke atas sebesar 29,8%. Data epidemiologi menunjukkan bahwa peningkatan tekanan darah akan meningkatkan kejadian kardiovaskuler, sehingga hipertensi harus diobati dengan tepat. Penelitian ini bertujuan untuk mengetahui pengaruh rasionalitas penggunaan antihipertensi dengan standar guideline JNC 8 terhadap keberhasilan terapi hipertensi di RS Panti Waluyo Surakarta tahun 2016. Penelitian ini merupakan penelit
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5

Hernandez-Vila, Eduardo. "A Review of the JNC 8 Blood Pressure Guideline." Texas Heart Institute Journal 42, no. 3 (2015): 226–28. http://dx.doi.org/10.14503/thij-15-5067.

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6

Kaplan, Norman M. "JNC 8 or Too Much of a Good Thing." Journal of Clinical Hypertension 16, no. 4 (2014): 263–64. http://dx.doi.org/10.1111/jch.12284.

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7

Mancia, Giuseppe. "Strengths and limitations of the JNC 8 hypertension guidelines." Nature Reviews Cardiology 11, no. 4 (2014): 189–90. http://dx.doi.org/10.1038/nrcardio.2014.12.

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8

Blacher, Jacques, Hélène Lelong, Sandrine Kretz, Alexandra Yannoutsos, Takeshi Kondo, and Michel Safar. "Le JNC 8 est sorti… mais ce n’est pas le JNC 8 ! Nouvelles recommandations américaines pour la prise en charge de l’hypertension artérielle." La Presse Médicale 43, no. 10 (2014): 1048–55. http://dx.doi.org/10.1016/j.lpm.2014.03.031.

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9

Thomas, Riny, Sini Sam, P. Neelaphar, P. Shabeeb, and B. A. Vishwanath. "A Study on Prescribing Pattern of Antihypertensive in Chronic Kidney Disease Patients." Journal of Drug Delivery and Therapeutics 10, no. 3-s (2020): 75–81. http://dx.doi.org/10.22270/jddt.v10i3-s.4139.

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Background: Chronic kidney disease causes progressive loss of function which gradually occur overtime leading to decrease in GFR levels leading to dysfunction of renal system. Hypertension is found to be intermingled cause and overlapping complication in CKD. It is important to intervene the progression by controlling the blood pressure to prevent kidney failure by administration of anti-hypertensive. Objectives: To study current trends in anti-hypertensive prescription pattern in CKD patient and to evaluate the concurrent patterns are in adherence according to the guidelines mentioned. Method
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10

Feldman, Harvey, Kim Zuber, and Jane S. Davis. "Staying up to date with the JNC 8 hypertension guideline." Journal of the American Academy of Physician Assistants 27, no. 8 (2014): 44–49. http://dx.doi.org/10.1097/01.jaa.0000451865.17954.9b.

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11

Wilford Germino, F. "JNC 8: Expectations, Challenges, and Wishes-A Primary Care Perspective." Journal of Clinical Hypertension 11, no. 10 (2009): 573–76. http://dx.doi.org/10.1111/j.1751-7176.2009.00157.x.

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12

Bansal, Ravi, and Savita Bansal. "High blood pressure in adults: What’s new in JNC 8?" Indian Journal of Medical Specialities 5, no. 1 (2014): 85–86. http://dx.doi.org/10.7713/ijms.2014.0001.

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13

Murray, Gary L. "The Feasibility of Blood Pressure Control with Autonomic- Assisted Hypertension Therapy versus JNC 8 Therapy." Clinical Cardiology and Cardiovascular Interventions 3, no. 4 (2020): 01–08. http://dx.doi.org/10.31579/2641-0419/055.

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14

Mahajan, Rajiv. "Joint National Committee 8 report: How it differ from JNC 7." International Journal of Applied and Basic Medical Research 4, no. 2 (2014): 61. http://dx.doi.org/10.4103/2229-516x.136773.

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15

Materson, Barry J. "JNC 8 at Last! No Holy Grail in Hand, but Useful Recommendations." Journal of Clinical Hypertension 16, no. 4 (2014): 249–50. http://dx.doi.org/10.1111/jch.12283.

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16

Düsing, R. "Die US-amerikanische Hypertonie-Leitlinie 2014 des Joint National Committee: JNC 8." DMW - Deutsche Medizinische Wochenschrift 139, no. 19 (2014): 1016–18. http://dx.doi.org/10.1055/s-0034-1370057.

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17

Finks, Shannon, and Toni L. Ripley. "Sorting It Out: What JNC 8 Is and What It Is Not." Journal of Managed Care & Specialty Pharmacy 21, no. 2 (2015): 110–12. http://dx.doi.org/10.18553/jmcp.2015.21.2.110.

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18

Varakantham, Varsha, Ashok Kumar Kurakula Sailoo, and Dinesh Kumar Bharatraj. "Antihypertensive Prescription Pattern and Compliance to JNC 7 and JNC 8 at Tertiary Care Government Hospital, Hyderabad, India: A Cross-sectional Retrospective Study." Hospital Pharmacy 53, no. 2 (2017): 107–12. http://dx.doi.org/10.1177/0018578717738080.

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Background: The monitoring of hypertension treatment can provide insight into the rational drug use pattern. The objective of this study was to examine the antihypertensive medication use among South Indian adults with hypertension in compliance with the hypertension treatment guidelines (Seventh Joint National Committee [JNC 7] and JNC 8). Methods and Results: A total of 550 hypertensive people aged >25 years were included in this retrospective cross-sectional study. The order of drugs prescribed in the year 2012 was beta blockers (BB) > calcium channel blockers (CCB) > CCB + BB >
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19

Myers, Martin G., and Sheldon W. Tobe. "A Canadian Perspective on the Eighth Joint National Committee (JNC 8) Hypertension Guidelines." Journal of Clinical Hypertension 16, no. 4 (2014): 246–48. http://dx.doi.org/10.1111/jch.12307.

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20

Burns, Joseph, Dharam Persaud-Sharma, and Dollie Green. "Beyond JNC 8: implications for evaluation and management of hypertension in underserved populations." Acta Cardiologica 74, no. 1 (2018): 1–8. http://dx.doi.org/10.1080/00015385.2018.1435987.

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21

Cohen, Debbie L., and Raymond R. Townsend. "Will the Results of the ACCOMPLISH Trial Affect the Recommendations of JNC 8?" Journal of Clinical Hypertension 11, no. 2 (2009): 100–101. http://dx.doi.org/10.1111/j.1751-7176.2009.00075.x.

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22

Verma, Vikash, Mukesh Kumar, Arvind Gupta, Kavita Dhar, and Jyotshana Sharma. "A study on drug utilization pattern of antihypertensive drugs in hypertensive diabetic patients." International Journal of Basic & Clinical Pharmacology 8, no. 10 (2019): 2242. http://dx.doi.org/10.18203/2319-2003.ijbcp20194264.

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Background: Hypertension management is of paramount importance in diabetic patients for reduction of cardiovascular and other complications. The objective of the present study was to assess prescribing pattern of antihypertensive drugs in hypertensive type 2 diabetic patients and evaluate them by comparing with Eighth Joint National Committee (JNC-8) hypertension treatment guidelines.Methods: A prospective observational study was carried out on 110 hypertensive type 2 diabetic patients of age 41-80 years visiting outpatient department of Medicine at G.S. Medical College and Hospital, UP, India
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23

Bhore, A. S., Kalyani Khandare, and K. A. Bansod. "Prescription pattern and rationality of antihypertensive drugs in patients of type 2 diabetes with hypertension: a pilot study." International Journal of Research in Medical Sciences 7, no. 4 (2019): 982. http://dx.doi.org/10.18203/2320-6012.ijrms20191299.

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Background: As presence of hypertension (HTN) in type 2 diabetes significantly increases risk of morbidity and mortality, its control with rational use of antihypertensives is essential. Authors performed this study to understand the current prescribing pattern of antihypertensives in patients of type 2 diabetes and their assess the rationality to recommendations of JNC-8 guidelines.Methods: Authors performed a cross sectional survey of prescription of diagnosed patients of diabetes with HTN at a tertiary care hospital. Prescription of patients attending medicine OPD were scanned. Data was col
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24

Goldstein, Felicia C., Ihab M. Hajjar, Callie B. Dunn, Allan I. Levey, and Whitney Wharton. "The Relationship Between Cognitive Functioning and the JNC-8 Guidelines for Hypertension in Older Adults." Journals of Gerontology Series A: Biological Sciences and Medical Sciences 72, no. 1 (2016): 121–26. http://dx.doi.org/10.1093/gerona/glw181.

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25

Islam, Quazi Tarikul. "JNC 8: Evidence-Based Guideline for the Management of High Blood Pressure in Adults in 2014." Bangladesh Journal of Medicine 25, no. 1 (2015): 1–2. http://dx.doi.org/10.3329/bjmed.v25i1.25069.

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26

Olafiranye, Oladipupo, Ferdinand Zizi, Perry Brimah, et al. "Management of Hypertension among Patients with Coronary Heart Disease." International Journal of Hypertension 2011 (2011): 1–6. http://dx.doi.org/10.4061/2011/653903.

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Evidence suggests that coronary heart disease (CHD) is the most common outcome of hypertension. Hypertension accelerates the development of atherosclerosis, and sustained elevation of blood pressure (BP) can destabilize vascular lesions and precipitate acute coronary events. Hypertension can cause myocardial ischemia in the absence of CHD. These cardiovascular risks attributed to hypertension can be reduced by optimal BP control. Although several antihypertensive agents exist, the choice of agent and the appropriate target BP for patients with CHD remain controversial. In this succinct paper,
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27

Raju, Sivasakthi, Sam Solomon, Nithiyan N, Karthik K, Anns Clara Joseph, and Venkatanarayanan V. "Assessment of Prescribing Pattern for Hypertension and Comparison with JNC-8 Guidelines-Proposed Intervention by Clinical Pharmacist." Journal of Young Pharmacists 8, no. 2 (2016): 133–35. http://dx.doi.org/10.5530/jyp.2016.2.14.

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28

Hajjar, Ihab, Kristine J. Rosenberger, Ambar Kulshreshtha, Hilsa N. Ayonayon, Kristine Yaffe, and Felicia C. Goldstein. "Association of JNC-8 and SPRINT Systolic Blood Pressure Levels With Cognitive Function and Related Racial Disparity." JAMA Neurology 74, no. 10 (2017): 1199. http://dx.doi.org/10.1001/jamaneurol.2017.1863.

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29

Reisin, Efrain, Raymond C. Harris, and Mahboob Rahman. "Commentary on the 2014 BP Guidelines from the Panel Appointed to the Eighth Joint National Committee (JNC 8)." Journal of the American Society of Nephrology 25, no. 11 (2014): 2419–24. http://dx.doi.org/10.1681/asn.2014040371.

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30

Abel, Nicole, Krysta Contino, Navjot Jain, et al. "Eighth joint national committee (JNC-8) guidelines and the outpatient management of hypertension in the African-American population." North American Journal of Medical Sciences 7, no. 10 (2015): 438. http://dx.doi.org/10.4103/1947-2714.168669.

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31

Kareem, Thasvi. "PRESCRIPTION PATTERN OF ANTI-HYPERTENSIVE DRUGS IN A TERTIARY CARE HOSPITAL IN KERALA AND ADHERENCE TO JNC-8 GUIDELINES." Universal Journal of Pharmaceutical Research 3, no. 3 (2018): 1–3. http://dx.doi.org/10.22270/ujpr.v3i3.158.

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32

Kelly, Michael S., Joseph J. Saseen, and Joel C. Marrs. "Assessment of achieved systolic blood pressure in newly treated hypertensive patients aged 60–79 years before and after Eighth Joint National Committee recommendations." Therapeutic Advances in Cardiovascular Disease 11, no. 2 (2016): 63–71. http://dx.doi.org/10.1177/1753944716684463.

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Objective: To determine whether patients who were newly prescribed antihypertensive therapy after the Eighth Joint National Committee (JNC 8) update were treated to a relaxed systolic blood pressure (SBP) goal compared with patients treated before the update. Methods: A retrospective cohort study approved by the Colorado Multiple Institutional Review Board. Patients aged 60–79 years, without diabetes or chronic kidney disease (CKD), newly treated for hypertension at a University of Colorado primary care clinics were included. The mean first-achieved and last-stable SBPs of patients newly presc
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Malpani, Ashok Kumar, Manjunath Waggi, Palash Panja, and Thella Monica Christien. "Study of Prescribing Pattern of Antihypertensive Drugs and Evaluation of the Prescription with JNC 8 Guidelines in North Karnataka Hospital." Indian Journal of Pharmacy Practice 11, no. 4 (2018): 193–97. http://dx.doi.org/10.5530/ijopp.11.4.40.

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34

Halboup, Abdulsalam M., Gamil Q. Othman, Mohammed M. Battah, Karem H. Alzoubi, and Hebah Sallom. "Awareness of Physicians in Yemen Toward High Blood Pressure Management According to the Eighth Joint National Committee (JNC 8) Guideline." International Journal of General Medicine Volume 13 (August 2020): 529–37. http://dx.doi.org/10.2147/ijgm.s265118.

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35

Lough, L., A. Seixas, G. Avirappattu, et al. "1046 Assessing Sleep-Related Hypertension Risks Using JNC 8 Guidelines: Analysis Of The National Health And Nutrition Examination Survey Data." Sleep 43, Supplement_1 (2020): A397. http://dx.doi.org/10.1093/sleep/zsaa056.1042.

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Abstract Introduction Associations between self-reported sleep duration and risk of hypertension (HTN) are well established. The level of sleep-related HTN risk based on the new JNC 8 classification guidelines requires further research. In this study, we modeled the associations of insufficient sleep with HTN using the National Health and Nutrition Examination Survey (NHANES). Methods Data were extracted from the 2006-2016 NHANES (n=38,540), a nationally representative study of the US civilian population. Self-reported demographic and sleep duration were determined from household interview que
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36

Watts, Vaibhav, Bhupinder Singh, and Jaswant Rai. "The effect of Ramipril and Telmisartan on blood pressure and insulin resistance in hypertensive patients." International Journal of Basic & Clinical Pharmacology 8, no. 6 (2019): 1262. http://dx.doi.org/10.18203/2319-2003.ijbcp20192186.

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Background: Angiotensin converting enzyme (ACE) inhibitors and Angiotensin II Receptor Blockers (ARBs) have become keystones of therapy for hypertension but there are very few studies where they have been compared with each other. This study attempted to compare the effect of Ramipril and Telmisartan on Blood Pressure and Insulin Resistance in Hypertensive patients (JNC 8).Methods: An open label, randomized, prospective and comparative study of twelve- week duration was conducted on 60 patients of hypertension (JNC-8), with the collaboration of Department of Pharmacology and Department of Medi
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Paudel, Navaraj, Prahlad Karki, Nikesh Raj Shreshta, and Sanjib Kumar Sharma. "White Coat Hypertension, relationship of stages of hypertension with end organ damage and diurnal variation of blood pressure in newly diagnosed hypertensive patients." Journal of Advances in Internal Medicine 1, no. 2 (2012): 56–59. http://dx.doi.org/10.3126/jaim.v1i2.6504.

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Introduction - Systemic hypertension is a disease attributable for various cardiovascular events. White coat hypertension is under diagnosed in Nepal and is usually treated as hypertension. However its prevalence in Nepal is not known. The relationship of stages of hypertension and diurnal variation of blood pressure with end organ damage is a current topic of research however such studies haven’t been done in Nepal. Methods - A Cross-sectional, Descriptive study including 80 patients was conducted over a period of 1 year from February 2008 to March 2010 at B. P. Koirala Institute of Health Sc
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Galán, Isabel, Úrsula Verdalles, Marisol García de Vinuesa, et al. "Impact of the application of the JNC 8 and KDIGO-2013 guidelines on hypertension and lipid control in a nephrology outpatient clinic." Nefrología (English Edition) 38, no. 4 (2018): 373–79. http://dx.doi.org/10.1016/j.nefroe.2018.05.003.

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39

K. Deepak Maharshi, T. Vani, M. Navaneetha, G. Jyothi, Shantveer Halcher, and Gururaj V Wadageri. "Prescription pattern of anti-hypertensive drugs among hypertensive patients at district hospital." International Journal of Research in Hospital and Clinical Pharmacy 1, no. 2 (2019): 57–61. http://dx.doi.org/10.33974/ijrhcp.v1i2.86.

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Background: To conduct a prospective observational study on prescribing pattern of anti-hypertensive drug in the department of general medicine in Government District hospital, Gulbarga. In this study it was aimed to evaluate the current practice of anti-hypertensive drug by comparing with JNC-8 guidelines in population. Objectives: The objective of our study is to determine the prescription pattern of antihypertensive drugs and adherence to JNC8 guidelines and to find out the most prescribed anti-hypertensive drugs. Methods: A Prospective Observational Study of 06 months was conducted. Undert
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40

Helmidanora, Rusdiati, and Triswanto Sentat. "EFEK HIPOTENSIF DARI ACEi DAN ARB PADA PASIEN DIABETES MELLITUS DAN HIPERTENSI DI RSUD. ABDUL WAHAB SYAHRANIE SAMARINDA." Jurnal Ilmiah Manuntung 3, no. 2 (2018): 186. http://dx.doi.org/10.51352/jim.v3i2.126.

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More than two-thirds of patients with type 2 diabetes also experience hypertension whose development coincides with hyperglycemia, where each disease has a tendency to influence the increased risk of other diseases. Sundry new guidelines, such as the National Joint Committee 8, the American Diabetes Association recommend blood pressure targets in the diabetic population of <140/90 mmHg to reduce cardiovascular risk and prevent the progression of nephropathy. This study aims to determine whether there is a difference in achieving blood pressure target < 140/90 mmHg according to Join Natio
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41

R., Velvizhy, and Johan Pandian J. "A prospective comparative efficacy of azilsartan and telmisartan in hypertensive patients." International Journal of Basic & Clinical Pharmacology 9, no. 8 (2020): 1232. http://dx.doi.org/10.18203/2319-2003.ijbcp20203140.

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Background: Hypertension (HT) is defined as either a sustained systolic blood pressure of greater than 140 mmHg or a sustained diastolic blood pressure of greater than 90 mmHg, according to joint national committee (JNC VIII) on hypertension.Methods: A prospective, open, randomized parallel group comparative study of AZL versus telmisartan was done in patients of stage-I HT. The study included 80 patients, 40 in each group (group I and group II) coming to the Department of Pharmacology, Mahatma Gandhi Medical College and Research Institute, Pillayarkuppam, Pondicherry from January 2016 to Dece
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Severova-Andreevska, Galina, Ilina Danilovska, Aleksandar Sikole, Zivko Popov, and Ninoslav Ivanovski. "Hypertension after Kidney Transplantation: Clinical Significance and Therapeutical Aspects." Open Access Macedonian Journal of Medical Sciences 7, no. 7 (2019): 1241–45. http://dx.doi.org/10.3889/oamjms.2019.264.

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Most of the kidney transplanted patients develop arterial hypertension after renal transplantation. Together with very well-known and usual risk factors, post-transplant hypertension contributes to the whole cardiovascular morbidity and mortality in the kidney transplant population. The reasons of post-transplant hypertension are factors related to donors and recipients, immunosuppressive therapy like Calcineurin Inhibitors (CNI) and surgery procedures (stenosis and kinking of the renal artery and ureteral obstruction). According to Eighth National Committee (JNC 8) recommendations, blood pres
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Nedogoda, S. V. "The role of bisoprolol in the management of patients with arterial hypertension." Systemic Hypertension 13, no. 3 (2016): 32–34. http://dx.doi.org/10.26442/sg29141.

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According to the different recommendations (NICE, JNC-8, ASH/ISH) concerning the treatment of AH, β-blockers are in 3rd-4th place among the other antihypertensive drugs (AHD), because the results of various meta-analyses show that their antihypertensive activity was less potent in comparison with other classes of drugs, their worst impact on hard endpoints (especially in people over 60). The application of beta-blockers can increase the risk of diabetes mellitus (especially in combination of thiazide-type diuretics) and shows negative effects on aortic elasticity. However, "new" β-blockers occ
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Agustina, Putri S., Em Yunir, Pukovisa Prawiroharjo, Johanda Damanik, and Rani Sauriasari. "Comparison of Effects of ACEIs and ARBs on Albuminuria and Hyperkalemia in Indonesian Hypertensive Type 2 Diabetes Mellitus Patients." International Journal of Hypertension 2020 (July 30, 2020): 1–8. http://dx.doi.org/10.1155/2020/5342161.

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Purpose. Due to economic consideration, Indonesia’s formulary restrictions are at odds with the treatment guidelines of the American Diabetes Association (ADA) and the Eighth Joint National Committee (JNC 8). ADA and JNC 8 equally recommend the prescription of an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB) for hypertensive patients with type 2 diabetes mellitus (T2DM) with overt proteinuria (urine albumin to creatinine ratio (UACR) ≥ 300 mg/g creatinine). However, since 1 April 2018, Indonesian formulary restricted telmisartan and valsartan only for
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Singh, Parminder, Rahat Kumar Sharma, and Jaswinder Singh. "Study of Prescribing Pattern and Adverse Drug Reactions in Hypertensive Patients with Comorbidities as per JNC 8 Hypertension Guidelines in a Tertiary Care Hospital of Punjab." Journal of Evidence Based Medicine and Healthcare 7, no. 19 (2020): 931–37. http://dx.doi.org/10.18410/jebmh/2020/204.

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46

Hiremath, Jagdish S., Anoop L. Hajare, Sunny R. Chinchansur, Arindam Dey, and Rishi Jain. "Azilsartan: the novel ARB with unique mechanism of action." International Journal of Basic & Clinical Pharmacology 6, no. 3 (2017): 482. http://dx.doi.org/10.18203/2319-2003.ijbcp20170458.

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Hypertension is attributed to be one of the major risk factors in the pathophysiology of ischemic heart disease, stroke, heart failure and renal dysfunction. Angiotensin receptor blockers (ARBs) are one of the first line drugs recommended for clinical use in hypertension by JNC 8. Azilsartan is the recent addition to this family of ARBs and is perceived as one of the potent antihypertensive drugs today. Azilsartan was developed by replacing the tetrazole ring in candesartan with a 5 member oxo-oxadiazole ring. In India Azisartan was recently approved by DCGI in December 2016 for use in hyperte
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47

Alaydrus, Syafika, and Natalia Toding. "Pola Penggunaan Obat Hipertensi Pada Pasien Geriatri Di Rumah Sakit Anutapura Palu Periode 08 Juli-08 Agustus 2019." Jurnal Mandala Pharmacon Indonesia 5, no. 02 (2019): 65–73. http://dx.doi.org/10.35311/jmpi.v5i02.46.

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Hipertensi merupakan faktor resiko utama penyakit-penyakit kardiovaskular yang menjadi penyebab kematian tertinggi di Indonesia. Sementara itu, peningkatan jumlah usia lanjut akan berpengaruh pada berbagai aspek kehidupan salah satunya pada perubahan fisik dalam sistem kardiovaskular. Tujuan penelitian ini adalah untuk mengetahui pola dan kesesuaian terapi penggunaan obat hipertensi pada pasien geriatri di RSU Anutapura Palu. Kesesuaian terapi dalam penelitian ini dilakukan dengan mengevaluasi kerasionalan terapi yang meliputi tepat pasien, tepat obat dan tepat dosis. Jenis dan rancangan penel
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48

Shah, Jay, and Avinash Balraj. "Drug utilization pattern of antihypertensive agents in patients of hypertensive nephropathy in a tertiary care hospital: a cross sectional study." International Journal of Basic & Clinical Pharmacology 6, no. 9 (2017): 2131. http://dx.doi.org/10.18203/2319-2003.ijbcp20173636.

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Background: Objective of the study was to determine the drug utilization pattern of antihypertensive agents in patients of hypertensive nephropathy in a tertiary care teaching hospital.Methods: This was a prospective observational study carried out in Index medical college and Hospital, Indore over a period of three 4 months. A total of 60 patients aged 40-79 years taking treatment for hypertension with associated nephropathy were enrolled in the study. All the relevant data were collected and drug utilization pattern of antihypertensive agents was determined. The study evaluated the percentag
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Leibundgut, Gregor. "Blutdruckgrenzwerte – je tiefer, desto besser?" Therapeutische Umschau 72, no. 6 (2015): 381–88. http://dx.doi.org/10.1024/0040-5930/a000690.

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Arterielle Hypertonie stellt einen weit verbreiteten Risikofaktor für kardiovaskuläre Erkrankungen dar. Der Nutzen einer konsequenten medikamentösen Therapie geht proportional einher mit dem Ausmaß der Blutdrucksenkung. Durch Extrapolation dieses Zusammenhangs entstand die Annahme „je niedriger, desto besser“ und wurde allgemein akzeptiert. Inzwischen haben mehrere Studien einen Anstieg der Morbidität und Mortalität bei einer übermäßigen Blutdrucksenkung (J-Kurve) gefunden. Andere wiederum fanden eine lineare Korrelation. Insgesamt bleibt ein j-förmiger Zusammenhang umstritten und gilt nicht f
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Galán, Isabel, Úrsula Verdalles, Marisol García de Vinuesa, et al. "Impacto de la aplicación del 8. o JNC y de las guías KDIGO-2013 en el control de la hipertensión arterial y los lípidos en una consulta de Nefrología." Nefrología 38, no. 4 (2018): 379–85. http://dx.doi.org/10.1016/j.nefro.2017.10.003.

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