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1

Engelhardt, Michael, Arne Hildebrand, Dagmar Lange, and Thomas C. Schmidt. "Semantic overlays in educational content networks – the hylOs approach." Campus-Wide Information Systems 23, no. 4 (2006): 254–67. http://dx.doi.org/10.1108/10650740610704126.

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PurposeThe paper, aims to introduce an educational content management system Hypermedia Learning Objects System (hylOs), which is fully compliant to the IEEE LOM eLearning object metadata standard. Enabled through an advanced authoring toolset, hylOs allows the definition of instructional overlays of a given eLearning object mesh.Design/methodology/approachIn educational content management, simple file distribution is considered insufficient. Instead, IEEE LOM standardised eLearning objects have been well established as the basic building blocks for educational online content. They are nicely
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2

Chen, Chiung-Yao. "Delving into Hearing Threshold of the Delay Gap of Initial Reflection in a Room by Using the Response of Cortical Brainwaves." Applied Sciences 13, no. 21 (2023): 11856. http://dx.doi.org/10.3390/app132111856.

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In this study, the apparent variation ranges of acoustical parameters were investigated in a concert hall. The initial time delay gap (ITDG) was evaluated in terms of its just noticeable difference (JND) through two instruments, the cello and the trumpet. Even though the IDTG values were prolonged over the measurements and were not significantly varied, an ITDG range of 22–220 ms in increments of 91 steps was produced electro-acoustically in an anechoic chamber. The result of JNDc (Δgap/gap) was rated by 50% “different” judgement ranges for the cello and trumpet tracks, respectively. The effec
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3

Ji, Wan Jun, Xu Qiao, and Yun Hai Xia. "The Implement of Java Calling C++ Program by JNI Technology." Applied Mechanics and Materials 701-702 (December 2014): 1077–80. http://dx.doi.org/10.4028/www.scientific.net/amm.701-702.1077.

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More and more enterprises are going to expand the business to the Internet and mobile terminals, at the same time, they are unwilling to give up the traditional applications not written in java, so questions come. The author has a deep research on JNI in java during the process of solving problems. This article simply introduces the JNI technology, and combines with the concrete instance to complete JNI cross-platform calling for VC++ program that reflects the using value of JNI technology.
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Liu, Sheng Hui, Hai Huang, Zhi Wei Liu, and Su Zhuang. "Design of a Fast JND Algorithm Based on Discrete Wavelet Transform and its VLSI Implementation." Applied Mechanics and Materials 380-384 (August 2013): 1538–41. http://dx.doi.org/10.4028/www.scientific.net/amm.380-384.1538.

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The computation of JND is very complex, which makes it difficult to embed it into integrated circuits. To solve this problem, Haar-DWT based JND model is exploited and its corresponding pipeline architecture is developed in this paper. To evaluate its performance, the architecture is modeled with hardware description language, and implemented by SMIC 0.18um technology. The area of JND core is 42052 gates, which is significantly smaller than the full band JND based architecture. From the experiment results, the system goes on well at 161 MHz and achieves 78% time saving compared with the full b
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Coe, Patrick, Grigori Evreinov, Mounia Ziat, and Roope Raisamo. "What the Mind Can Comprehend from a Single Touch." Multimodal Technologies and Interaction 8, no. 6 (2024): 45. http://dx.doi.org/10.3390/mti8060045.

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This paper investigates the versatility of force feedback (FF) technology in enhancing user interfaces across a spectrum of applications. We delve into the human finger pad’s sensitivity to FF stimuli, which is critical to the development of intuitive and responsive controls in sectors such as medicine, where precision is paramount, and entertainment, where immersive experiences are sought. The study presents a case study in the automotive domain, where FF technology was implemented to simulate mechanical button presses, reducing the JND FF levels that were between 0.04 N and 0.054 N to the JN
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Zhang, Xin Wei, Yin Shan Jia, Chun Hua Yu, Zi Long Chen, Cheng Wang, and Da Zhou Zhu. "Application of Java-Called DLL in Crop Breeding Data Analysis System." Applied Mechanics and Materials 543-547 (March 2014): 3243–47. http://dx.doi.org/10.4028/www.scientific.net/amm.543-547.3243.

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The collected massive data during the breeding process usually cost plenty of human power. Therefore, it is urgent to create highly-efficient specific breeding data analysis software to assist breeders to screen fine varieties. For this reason, this paper developed a breeding data management analysis system by taking MyEclipse as development tool, which covers various statistical analysis techniques. In the development process of each algorithm module, JNI technology is adopted to realize Java-called DLL and complete algorithm call, improving the execution efficiency of a large number of arith
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7

He, Yi, Tian Li Li, and Ying Qian Zhang. "Research of Image Edge Detection Algorithms Based on Android Platform." Applied Mechanics and Materials 644-650 (September 2014): 1154–57. http://dx.doi.org/10.4028/www.scientific.net/amm.644-650.1154.

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With mobile platform development there are more and more Android-based image processing applications. The principles of four kinds of edge detection algorithms are analyzed in this paper and such algorithms are realized by adopting JNI technology based on android platform. At last the effect and efficiency of such algorithms are also compared and summarized.
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8

Qu, Jiasheng, Wei Song, Xiangchun Liu, Lizhi Zhao, and Xiaobing Zhao. "A Novel Improved Reversible Visible Image Watermarking Algorithm Based on Grad-CAM and JND." Security and Communication Networks 2021 (January 25, 2021): 1–17. http://dx.doi.org/10.1155/2021/6652897.

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With the rapid access convenience of content brought by 5G technology, the integrity protection of content becomes more important. The reversible visible watermarking algorithm has attracted more attention due to its effective content protection. In this paper, a novel improved reversible visible image watermarking scheme based on gradient-weighted class activation mapping (Grad-CAM) and the just noticeable difference (JND) model has been presented. The proposed region of interest (ROI) selection strategy is used to locate the main protected body of images for watermark embedding. Divide the w
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9

Zhao, Jinchao, Yihan Wang, and Qiuwen Zhang. "Fast CU Size Decision Method Based on Just Noticeable Distortion and Deep Learning." Scientific Programming 2021 (December 8, 2021): 1–10. http://dx.doi.org/10.1155/2021/3813116.

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With the development of broadband networks and high-definition displays, people have higher expectations for the quality of video images, which also brings new requirements and challenges to video coding technology. Compared with H.265/High Efficiency Video Coding (HEVC), the latest video coding standard, Versatile Video Coding (VVC), can save 50%-bit rate while maintaining the same subjective quality, but it leads to extremely high encoding complexity. To decrease the complexity, a fast coding unit (CU) size decision method based on Just Noticeable Distortion (JND) and deep learning is propos
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10

Eastman, P. "Technology Lends Itself to Breast Imaging." JNCI Journal of the National Cancer Institute 86, no. 22 (1994): 1669–71. http://dx.doi.org/10.1093/jnci/86.22.1669.

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11

Friedman, R. "Nano Dot Technology Enters Clinical Trials." JNCI Journal of the National Cancer Institute 103, no. 19 (2011): 1428–29. http://dx.doi.org/10.1093/jnci/djr400.

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12

Hollon, T. "Comparing Microarray Data: What Technology Is Needed?" JNCI Journal of the National Cancer Institute 93, no. 15 (2001): 1126–27. http://dx.doi.org/10.1093/jnci/93.15.1126.

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13

Jacobs-Perkins, A. "Scientists Navigate Bermuda Triangle Of Technology Transfer." JNCI Journal of the National Cancer Institute 82, no. 7 (1990): 546–48. http://dx.doi.org/10.1093/jnci/82.7.546.

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14

Holzman, D. "Screening Technology Explained: Getting Down to the Bases." JNCI Journal of the National Cancer Institute 87, no. 22 (1995): 1664. http://dx.doi.org/10.1093/jnci/87.22.1664.

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15

Narayanan, R. "Harnessing the Power of Antisense Technology for Combination Chemotherapy." JNCI Journal of the National Cancer Institute 89, no. 2 (1997): 107–8. http://dx.doi.org/10.1093/jnci/89.2.107.

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16

McGivney, W. T. "Proposal for Assuring Technology Competency and Leadership in Medicine." JNCI Journal of the National Cancer Institute 84, no. 10 (1992): 742–44. http://dx.doi.org/10.1093/jnci/84.10.742.

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17

Newman, Michael E. "Space Imaging Technology Yields Down-to-Earth Cancer Benefits." JNCI: Journal of the National Cancer Institute 83, no. 14 (1991): 986–87. http://dx.doi.org/10.1093/jnci/83.14.986.

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18

Tang, You Lu, and Hong Du. "Feasibility Study on the Method of Java Combined with OSG." Applied Mechanics and Materials 536-537 (April 2014): 607–10. http://dx.doi.org/10.4028/www.scientific.net/amm.536-537.607.

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The purpose of this study is to combine Java and OpenSceneGraph(OSG) for the development of 3D scene graph, and to play their individual advantages. This paper introduced the scene management, rendering process and other relevant theoretical knowledge about OSG, and elaborated the method about using OSG in java environment through java's JNI technology. According to this method, the constructing, rendering and dynamic roam of a simple 3D scene graph about one frontage road were realized, and the concrete realization processes of the application introduced in this essay. The results show java c
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19

Weed, D. L. "Between Science and Technology: the Case of Antihistamines and Cancer." JNCI Journal of the National Cancer Institute 86, no. 10 (1994): 740–41. http://dx.doi.org/10.1093/jnci/86.10.740.

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20

Bekelman, J. E., and S. M. Hahn. "The Body of Evidence for Advanced Technology in Radiation Oncology." JNCI Journal of the National Cancer Institute 105, no. 1 (2012): 6–7. http://dx.doi.org/10.1093/jnci/djs508.

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21

Taylor, E. "Interactive Technology Enters Realm of Cancer Education." JNCI Journal of the National Cancer Institute 86, no. 17 (1994): 1272–74. http://dx.doi.org/10.1093/jnci/86.17.1272-a.

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22

Finn, R. "Hospital Marketing Practices: When Is It Appropriate to Advertise New Technology?" JNCI Journal of the National Cancer Institute 93, no. 1 (2001): 6–7. http://dx.doi.org/10.1093/jnci/93.1.6.

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23

Mok, S. C., J. Chao, S. Skates, et al. "Prostasin, a Potential Serum Marker for Ovarian Cancer: Identification Through Microarray Technology." JNCI Journal of the National Cancer Institute 93, no. 19 (2001): 1458–64. http://dx.doi.org/10.1093/jnci/93.19.1458.

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24

Spaan, Mandy, Alexandra W. van den Belt-Dusebout, Cornelis B. Lambalk, et al. "Long-Term Risk of Ovarian Cancer and Borderline Tumors After Assisted Reproductive Technology." JNCI: Journal of the National Cancer Institute 113, no. 6 (2020): 699–709. http://dx.doi.org/10.1093/jnci/djaa163.

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Abstract Background Long-term effects of assisted reproductive technology (ART) on ovarian tumor risk are unknown. Methods This nationwide cohort study comprises 30 625 women who received ovarian stimulation for ART in 1983-2000 and 9988 subfertile women not treated with ART. Incident invasive and borderline ovarian tumors were ascertained through linkage with the Netherlands Cancer Registry and the Dutch Pathology Registry until July 2018. Ovarian tumor risk in ART-treated women was compared with risks in the general population and the subfertile non-ART group. Statistical tests were 2-sided.
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25

Wan, Wenbo, Jun Wang, Jing Li, Jiande Sun, Huaxiang Zhang, and Ju Liu. "Hybrid JND model-guided watermarking method for screen content images." Multimedia Tools and Applications 79, no. 7-8 (2018): 4907–30. http://dx.doi.org/10.1007/s11042-018-6860-1.

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26

Bae, Sung-Ho, and Munchurl Kim. "A DCT-Based Total JND Profile for Spatiotemporal and Foveated Masking Effects." IEEE Transactions on Circuits and Systems for Video Technology 27, no. 6 (2017): 1196–207. http://dx.doi.org/10.1109/tcsvt.2016.2539862.

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27

Tuma, R. S. "A Big Trial for a New Technology: TransBIG Project Takes Microarrays Into Clinical Trials." JNCI Journal of the National Cancer Institute 96, no. 9 (2004): 648–49. http://dx.doi.org/10.1093/jnci/96.9.648.

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28

Kaluzny, A. D., T. Ricketts, R. Warnecke, et al. "Evaluating Organizational Design To Assure Technology Transfer: The Case of the Community Clinical Oncology Program." JNCI Journal of the National Cancer Institute 81, no. 22 (1989): 1717–25. http://dx.doi.org/10.1093/jnci/81.22.1717.

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29

de la Fuente, Alexandre, Lorena Alonso-Alconada, Clotilde Costa, et al. "M-Trap: Exosome-Based Capture of Tumor Cells as a New Technology in Peritoneal Metastasis." Journal of the National Cancer Institute 107, no. 9 (2015): djv184. http://dx.doi.org/10.1093/jnci/djv184.

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30

McMahon, James, Steven Schmid, Owen Weislow, et al. "Feasibility of Cellular Microencapsulation Technology for Evaluation of Anti-Human Immunodeficiency Virus Drugs In Vivo." JNCI: Journal of the National Cancer Institute 82, no. 22 (1990): 1761–65. http://dx.doi.org/10.1093/jnci/82.22.1761.

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31

Wang, Jun, and Wenbo Wan. "A novel attention-guided JND Model for improving robust image watermarking." Multimedia Tools and Applications 79, no. 33-34 (2020): 24057–73. http://dx.doi.org/10.1007/s11042-020-09102-2.

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32

Yeh, Chiu-Yu, and Yaw-Shyan Tsay. "Using Machine Learning to Predict Indoor Acoustic Indicators of Multi-Functional Activity Centers." Applied Sciences 11, no. 12 (2021): 5641. http://dx.doi.org/10.3390/app11125641.

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In Taiwan, activity centers such as school auditoriums and gymnasiums are common multi-functional spaces that are often used for performances, singing, and speeches. However, most cases are designed using only Sabine’s equation for architectural acoustics. Although that estimation formula is simple and fast, the calculation process ignores many details. Furthermore, while more accurate analysis can be obtained through acoustics simulation software, it is more complicated and time-consuming and thus is rarely used in practical design. The purpose of this study is to use machine learning to prop
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33

Wang, Hongkui, Li Yu, Haibing Yin, Tiansong Li, and Shengwei Wang. "An improved DCT-based JND estimation model considering multiple masking effects." Journal of Visual Communication and Image Representation 71 (August 2020): 102850. http://dx.doi.org/10.1016/j.jvcir.2020.102850.

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34

Li, Xin, Yu Jiang, Jian Jun Song, and Wei Li Cui. "WSN Image Watermarking Algorithm Based on Multi-Wavelet." Applied Mechanics and Materials 44-47 (December 2010): 3912–16. http://dx.doi.org/10.4028/www.scientific.net/amm.44-47.3912.

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A WSN image watermarking algorithm based on multi-wavelet was proposed. When the instability of image transmission in wireless sensor networks was considered, the proposed algorithm can increase the capacity of the image watermark. In this paper, the wavelet transform coefficients were analyzed by the noise visibility function. And the bits were embedded into the coefficients which have more ability to the tolerance of the noise according to the designated threshold. We achieved the adaptive adjustment in the watermarking strength combined with the JND in the wavelet domain. The experimental r
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Rai, Laxmisha, Zhiyuan Wang, Amila Rodrigo, Zhaopeng Deng, and Haiqing Liu. "Software Development Framework for Real-Time Face Detection and Recognition in Mobile Devices." International Journal of Interactive Mobile Technologies (iJIM) 14, no. 04 (2020): 103. http://dx.doi.org/10.3991/ijim.v14i04.12077.

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With the rapid use of Android OS in mobile devices and related products, face recognition technology is an essential feature, so that mobile devices have a strong personal identity authentication. In this paper, we propose Android based software development framework for real-time face detection and recognition using OpenCV library, which is applicable in several mobile applications. Initially, the Gaussian smoothing and gray-scale transformation algorithm is applied to preprocess the source image. Then, the Haar-like feature matching method is used to describe the characteristics of the opera
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36

Qi, Wenfa, Yuxin Liu, Sirui Guo, Xiang Wang, and Zongming Guo. "An Adaptive Visible Watermark Embedding Method based on Region Selection." Security and Communication Networks 2021 (March 3, 2021): 1–11. http://dx.doi.org/10.1155/2021/6693343.

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Aiming at the problem that the robustness, visibility, and transparency of the existing visible watermarking technologies are difficult to achieve a balance, this paper proposes an adaptive embedding method for visible watermarking. Firstly, the salient region of the host image is detected based on superpixel detection. Secondly, the flat region with relatively low complexity is selected as the embedding region in the nonsalient region of the host image. Then, the watermarking strength is adaptively calculated by considering the gray distribution and image texture complexity of the embedding r
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37

Savarese, Marco, Talha Qureshi, Annalaura Torella, et al. "Identification and Characterization of Splicing Defects by Single-Molecule Real-Time Sequencing Technology (PacBio)." Journal of Neuromuscular Diseases 7, no. 4 (2020): 477–81. http://dx.doi.org/10.3233/jnd-200523.

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Although DNA-sequencing is the most effective procedure to achieve a molecular diagnosis in genetic diseases, complementary RNA analyses are often required. Reverse-Transcription polymerase chain reaction (RT-PCR) is still a valuable option when the clinical phenotype and/or available DNA-test results address the diagnosis toward a gene of interest or when the splicing effect of a single variant needs to be assessed. We use Single-Molecule Real-Time sequencing to detect and characterize splicing defects and single nucleotide variants in well-known disease genes (DMD, NF1, TTN). After proper op
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38

Hu, Hwai-Tsu, and Jieh-Ren Chang. "Dual image watermarking by exploiting the properties of selected DCT coefficients with JND modeling." Multimedia Tools and Applications 77, no. 20 (2018): 26965–90. http://dx.doi.org/10.1007/s11042-018-5900-1.

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39

Farber, Rachel, Nehmat Houssami, Sally Wortley, et al. "Impact of Full-Field Digital Mammography Versus Film-Screen Mammography in Population Screening: A Meta-Analysis." JNCI: Journal of the National Cancer Institute 113, no. 1 (2020): 16–26. http://dx.doi.org/10.1093/jnci/djaa080.

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Abstract Background Breast screening programs replaced film mammography with digital mammography, and the effects of this practice shift in population screening on health outcomes can be measured through examination of cancer detection and interval cancer rates. Methods A systematic review and random effects meta-analysis were undertaken. Seven databases were searched for publications that compared film with digital mammography within the same population of asymptomatic women and reported cancer detection and/or interval cancer rates. Results The analysis included 24 studies with 16 583 743 sc
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40

Sorrentino, Antonio. "Induced pluripotent stem cells: the long-expected revolution in medical science and practice?" Journal of Nucleic Acids Investigation 1, no. 1 (2010): 1. http://dx.doi.org/10.4081/jnai.2010.1625.

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Within the matter of a few years, development of the somatic reprogramming technology to generate induced pluripotent stem (iPS) cells has contributed enormously to the stem cell research field. We learned that differentiated adult cells possess an unrestricted plasticity that allows them to be driven back to their embryonic or pluripotent state, but owing to the juvenile nature of this novel science chapter, there are many unanswered questions and dilemmas. It is indisputable, however, that iPS cells potentially could represent the jack-of-all-trades remedy in areas of medicine ranging from t
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41

Papadimitriou, Stergios, and Lefteris Moussiades. "The design of JVM and native libraries in ScalaLab for efficient scientific computation." International Journal of Modeling, Simulation, and Scientific Computing 09, no. 05 (2018): 1850037. http://dx.doi.org/10.1142/s179396231850037x.

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ScalaLab is a MATLAB-like environment for the Java Virtual Machine (JVM). ScalaLab is based on the Scala programming language. It utilizes an extensive set of Java and Scala scientific libraries and also has access to many native C/C[Formula: see text] scientific libraries by using mainly the Java Native Interface (JNI). The performance of the JVM platform is continuously improved at a fast pace. Today JVM can effectively support demanding high-performance computing and scales well on multicore platforms. However, sometimes optimized native C/[Formula: see text] code can yield even better perf
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42

Endiyono, Endiyono, M. Hanif Prasetya Adhi, Royan Royan, and Arif Johar Taufiq. "Effectiveness of digital resuscitation pad technology innovation on the accuracy of cardiac and lung resuscitation compression." JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) 12, no. 1 (2024): 11. http://dx.doi.org/10.21927/jnki.2024.12(1).11-20.

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<p><strong><em>Background: </em></strong><em>Cardiac arrest is a crucial problem because it has a short rescue time and requires optimal assistance competence. The global incidence of cardiac arrest is 50-60 per 100,000 per year, while in Indonesia it is 10,000 per year or 30 incidents every day. This is an important problem that must be addressed immediately, apart from improving skills, by using innovative supporting tools. This tool is still very limited and does not even exist in Indonesia.</em></p><p><strong><em>Objectives:
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Salazar-León, Jonathan, Fabiola Reyes-Román, Angélica Meneses-Acosta, et al. "Silencing of hpv16 e6 and e7 oncogenic activities by small interference rna induces autophagy and apoptosis in human cervical cancer cells." Journal of Nucleic Acids Investigation 2, no. 1 (2011): 10. http://dx.doi.org/10.4081/jnai.2011.2583.

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Cervical cancer is the second most common form of death by cancer in women worldwide and has special attention for the development of new treatment strategies. Human Papilloma Virus (HPV) persistent infection is the main etiological agent of this neoplasia, and the main cellular transformation mechanism is by disruption of p53 and pRb function by interaction with HPV E6 and E7 oncoproteins. This generates alterations in cellular differentiation and cellular death inhibition. Thus, HPV E6 and E7 oncogenes represent suitable targets for the development of gene therapy strategies against cervical
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44

Leach, Corinne R., Catherine M. Alfano, Jessica Potts, et al. "Personalized Cancer Follow-Up Care Pathways: A Delphi Consensus of Research Priorities." JNCI: Journal of the National Cancer Institute 112, no. 12 (2020): 1183–89. http://dx.doi.org/10.1093/jnci/djaa053.

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Abstract Development of personalized, stratified follow-up care pathways where care intensity and setting vary with needs could improve cancer survivor outcomes and efficiency of health-care delivery. Advancing such an approach in the United States requires identification and prioritization of the most pressing research and data needed to create and implement personalized care pathway models. Cancer survivorship research and care experts (n = 39) participated in an in-person workshop on this topic in 2018. Using a modified Delphi technique—a structured, validated system for identifying consens
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Katona, Bryson W., Dana Farengo Clark, and Susan M. Domchek. "CDH1 on Multigene Panel Testing: Look Before You Leap." JNCI: Journal of the National Cancer Institute 112, no. 4 (2019): 330–34. http://dx.doi.org/10.1093/jnci/djz229.

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Abstract Multigene panel testing (MGPT) has become a critical component of cancer risk assessment in clinical practice. As technology and access improve and costs decrease, more individuals than ever are undergoing MGPT for genetic evaluation. One gene that deserves special consideration when included on MGPT is CDH1, which codes for the cell-cell adhesion protein E-cadherin. Pathogenic and likely pathogenic germline variants in CDH1 have been associated with hereditary diffuse gastric cancer syndrome, and in highly penetrant families, testing for these variants is critical for proper risk man
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46

Chojnacki, Bartlomiej, Maria Brzóska, and Joanna A. Fijałkowska. "Comparison of Different Omnidirectional Sound Sources with the Validation of Coupled Speakers as a Measurement Source for Room Acoustics." Applied Sciences 13, no. 24 (2023): 13058. http://dx.doi.org/10.3390/app132413058.

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Omnidirectional sources used in room acoustics usually take the form of multi-speaker sources. Few alternatives for the most commonly used dodecahedral sound source have been derived recently. The project aimed to measure room acoustic parameters using three different sound sources: a dodecahedron, a cube, and a new source of two coupled loudspeakers. The measurements were made by rotating the sources every 15 degrees. The differences in the EDT, T30, D50, and C80 parameters in the function of the rotation angle of the sources were analyzed. Statistical analysis was carried out to examine the
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47

Parikh, Ravi B., Samuel U. Takvorian, Daniel Vader, et al. "Impact of the COVID-19 Pandemic on Treatment Patterns for Patients With Metastatic Solid Cancer in the United States." JNCI: Journal of the National Cancer Institute 114, no. 4 (2021): 571–78. http://dx.doi.org/10.1093/jnci/djab225.

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Abstract Background The COVID-19 pandemic has led to delays in patients seeking care for life-threatening conditions; however, its impact on treatment patterns for patients with metastatic cancer is unknown. We assessed the COVID-19 pandemic’s impact on time to treatment initiation (TTI) and treatment selection for patients newly diagnosed with metastatic solid cancer. Methods We used an electronic health record–derived longitudinal database curated via technology-enabled abstraction to identify 14 136 US patients newly diagnosed with de novo or recurrent metastatic solid cancer between Januar
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48

Cappella, Marisa, Pierre-François Pradat, Giorgia Querin, and Maria Grazia Biferi. "Beyond the Traditional Clinical Trials for Amyotrophic Lateral Sclerosis and The Future Impact of Gene Therapy." Journal of Neuromuscular Diseases 8, no. 1 (2021): 25–38. http://dx.doi.org/10.3233/jnd-200531.

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Amyotrophic lateral sclerosis (ALS) is a devastating and incurable motor neuron (MN) disorder affecting both upper and lower MNs. Despite impressive advances in the understanding of the disease’s pathological mechanism, classical pharmacological clinical trials failed to provide an efficient cure for ALS over the past twenty years. Two different gene therapy approaches were recently approved for the monogenic disease Spinal muscular atrophy, characterized by degeneration of lower MNs. This milestone suggests that gene therapy-based therapeutic solutions could be effective for the treatment of
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49

Hamza, Mohammad Khalid. "Web Evaluation Tool (WET): A Creative Web Tool for Online Educators." Journal of Educational Technology Systems 31, no. 3 (2003): 307–29. http://dx.doi.org/10.2190/l3nm-jndx-brxu-qfq5.

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The Nielsen/Net report Ratings 2000, reported that in 2002, online usage at work Jumped 17 Percent Year-Over-Year, driven by female office workers. Nearly 46 million American office workers logged onto the Web, the highest peak since January 2000. It was also predicted that the number of students using the Internet was expected to reach 13.5 million by 2002, an increase from 3.4 million who were using the Internet in 1995. United States colleges and universities, in the year 2000, offered in excess of 6,000 accredited courses on the Web. Furthermore, nearly 10 million people over the age of 16
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50

Kassem, Amany T., and Mahmoud M. S. Ali. "Effect of Hyamine-1622 Cationic Surfactant on Pertraction of Cerium (IV) Cations Through Emulsion Liquid Membranes." Journal of New Developments in Chemistry 3, no. 3 (2021): 1–21. http://dx.doi.org/10.14302/issn.2377-2549.jndc-21-3738.

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The present study aims to shed light directly towards the extraction of (IV) cerium ions using "liquid surfactant membrane" technology, "LSM" developed in the presence of synergistic cationic and nonionic materials. The effect of various factors such as Ce (IV) transport, synergistic surfactants, curing ratio, stir speed, temperature, and mixing time between the carrier and the cerium ion on the extraction rate was studied by LSM taking into account surfactant agents. The positive effect of benzethonium chloride "Hy-1622" on the extraction of cerium ion was demonstrated by LSMs technique. Expe
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