Academic literature on the topic 'Justicidin C'

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Journal articles on the topic "Justicidin C"

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Sciandrone, Barbara, Roméo Arago Dougué Kentsop, Roberta Pensotti, et al. "Toxicological Analysis of the Arylnaphthalene Lignan Justicidin B Using a Caenorhabditis elegans Model." Molecules 29, no. 23 (2024): 5516. http://dx.doi.org/10.3390/molecules29235516.

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The screening of plant-derived compounds with anti-cancer properties is a promising strategy to meet the growing need for new, safe and effective anti-cancer drugs. Justicidin B is a plants secondary metabolite that displays anti-cancer properties in several tumor cells. Therefore, it represents a good candidate. We used the 3R-compliant organism Caenorhabditis elegans to evaluate the safety of justicidin B produced by in vitro-grown adventitious roots of Linum lewisii. We showed that a dose of 100 µg/mL justicidin B does not affect worm vitality in either short-term or chronic administration;
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Luo, Jiaoyang, Yichen Hu, Jia'an Qin, and Meihua Yang. "Ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry and pharmacokinetic analysis of justicidin B and 6′-hydroxy justicidin C in rats." Journal of Separation Science 40, no. 3 (2016): 604–11. http://dx.doi.org/10.1002/jssc.201600961.

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Park, Ju-Eun, Juyeun Lee, Seung-Yong Seo, and Dongyun Shin. "Regioselective route for arylnaphthalene lactones: convenient synthesis of taiwanin C, justicidin E, and daurinol." Tetrahedron Letters 55, no. 4 (2014): 818–20. http://dx.doi.org/10.1016/j.tetlet.2013.12.014.

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Hitotsuyanagi, Yukio, Masatsugu Kobayashi, Masamoto Fukuyo, Koichi Takeya, and Hideji Itokawa. "A facile synthesis of the 4-aza-analogs of 1-arylnaphthalene lignans chinensin, justicidin B, and Taiwanin C." Tetrahedron Letters 38, no. 48 (1997): 8295–96. http://dx.doi.org/10.1016/s0040-4039(97)10204-0.

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Park, Ju-Eun, Juyeun Lee, Seung-Yong Seo, and Dongyun Shin. "ChemInform Abstract: Regioselective Route for Arylnaphthalene Lactones: Convenient Synthesis of Taiwanin C (I), Justicidin E (II), and Daurinol (III)." ChemInform 45, no. 28 (2014): no. http://dx.doi.org/10.1002/chin.201428220.

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HITOTSUYANAGI, Y., M. KOBAYASHI, M. FUKUYO, K. TAKEYA, and H. ITOKAWA. "ChemInform Abstract: A Facile Synthesis of the 4-Aza-Analogues of 1-Arylnaphthalene Lignans Chinensin, Justicidin B, and Taiwanin C." ChemInform 29, no. 7 (2010): no. http://dx.doi.org/10.1002/chin.199807171.

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Al-Abdallat, Ayed M., Batool K. Adayileh, Jamal S. Sawwan, et al. "Secondary Metabolites Profiling, Antimicrobial and Cytotoxic Properties of Commiphora gileadensis L. Leaves, Seeds, Callus, and Cell Suspension Extracts." Metabolites 13, no. 4 (2023): 537. http://dx.doi.org/10.3390/metabo13040537.

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Commiphora gileadensis L. is an important endangered medicinal plant that belongs to the family Burseraceae. In this study, C. gileadensis callus culture was established successfully using mature leaves as explants cultured on Murashige and Skoog (MS) media supplemented with 24.50 μM of indole butyric acid (IBA) and 2.22 μM 6-Benzylaminopurine (BAP) (callus induction media). The obtained callus was maintained on MS medium supplemented with 16.11 μM naphthalene acetic acid (NAA) in combination with 6.66 μM BAP, which resulted in a substantial increase in callus fresh and dry weights. The cell s
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Seko, Shinzo, Yoo Tanabe та Gohfu Suzukamo. "A novel synthesis of α- and β-halonaphthalenes via regioselective ring cleavage of aryl(gem-dihalocyclopropyl)methanols and its application to total synthesis of lignan lactones, justicidin e and taiwanin c". Tetrahedron Letters 31, № 47 (1990): 6883–86. http://dx.doi.org/10.1016/s0040-4039(00)97197-1.

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Boluda, Carlos José, José Piñero, Marialina Romero, et al. "Anti-leishmanial Activity of Justicidone and its Synthetic Precursors." Natural Product Communications 2, no. 2 (2007): 1934578X0700200. http://dx.doi.org/10.1177/1934578x0700200212.

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Justicidone, a C-5, C-8 dioxo-lignan of the arylnaphthalene type isolated from Justicia hyssopifolia, and its synthetic precursors were tested for the activity against Leishmania braziliensis and Leishmania amazonensis promastigotes in vitro. Justicidone showed activity against L. braziliensis with an IC50 of 181.90 μM, while, the diasteromeric mixture of one of its synthetic precursors exhibited activity against both parasite strains with an IC50 of 99.27 μM (L. braziliensis) and 181.75 μM (L. amazonensis). This activity has not previously been reported for dibenzylbutyrolactones and dioxo-li
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Boluda, Carlos J., Juan M. Trujillo, José A. Pérez, Hermelo López, Zulma Aragón, and Raquel G. Díaz. "Semisynthesis of Justicidone and a 1,2-Quinone Lignan. Cytotoxic Activity of Some Natural and Synthetic Lignans." Natural Product Communications 4, no. 2 (2009): 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400214.

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The dioxo-lignans of the arylnaphthalene-type named justicidone (2) and elenodione (3) were obtained from elenoside (1) through a short and efficient semisynthetic process. Justicidone (2), one of its synthetic precursors, 4-(benzo[d][1,3]dioxol-5-yl)-5,6,8-trimethoxy-3a,4-dihydronaphtho[2,3-c]furan-1(3H)-one (9), and the aglycone of elenoside (5) showed cytotoxic activity towards the HL-60 cell line (IC50 = 7.25 μM, 5.41 μM and 2.06 μM, respectively).
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Dissertations / Theses on the topic "Justicidin C"

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Ourhzif, El-Mahdi. "Synthèse et évaluation pharmacologique de composés originaux de la famille des méthoxynaphtalènes et lignanes arylnaphtalènes à visée antitumorale." Electronic Thesis or Diss., Université Clermont Auvergne (2021-...), 2022. http://www.theses.fr/2022UCFAC016.

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Le cancer du sein est la tumeur maligne la plus fréquente chez les femmes, il reste le premier en termes d’incidence (2,1 millions de nouveaux cas dans le monde en 2018) et de phénomènes de résistance des cellules cancéreuses aux différents traitements sont apparue. En raison de son impact majeur sur la population, cette maladie représente un problème de santé publique critique qui nécessite des recherches supplémentaires aux niveaux moléculaires afin de définir son traitement spécifique. Le règne végétal reste une source primordiale pour de nombreux chercheurs afin de trouver de nouvelles mol
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