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Relevant bibliographies by topics / Karaya gum and HPMC K100M

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Journal articles

Academic literature on the topic 'Karaya gum and HPMC K100M'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Karaya gum and HPMC K100M"

1

Naveen, Kumar HR, Kumar P. Ashok, V. Kulkarni Suresh, and K. Manjunath. "Development and Evaluation of Floating Sustained Release Bilayer Tablets Containing Drotaverine HCl." American Journal of PharmTech Research 12, no. 06 (2022): 62–74. https://doi.org/10.5281/zenodo.7407644.

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ABSTRACT Bilayer floating tablets of Drotaverine HCL were developed by direct compression method. Immediate release layer contains 20 mg of drug and super disintegrant sodium starch glycolate, serves the purpose of loading dose. Sustained release layer contained HPMC K100, natural polymers like xanthan gum, guar gum, karaya gum release the drug for 12 hours’ time. Sodium bicarbonate and citric acid are used to produce effervescence. Floating lag time of optimized tablet is 92 sec, whereas floating duration is more than 12 hours. FTIR results revealed that there was no interaction between

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2

Sana, Nusrat Praween* Dr. Kaushal Kishore Chandrul Pankaj Chasta. "Formulation And Characterization of Sustain Release Drug Delivery of Glycopyrrolate and Formoterol for The Treatment of Chronic Obstructive Pulmonary Disease (COPD)." International Journal of Pharmaceutical Sciences, no. 12 (December 22, 2024): 2853–69. https://doi.org/10.5281/zenodo.14543522.

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The objective of the current work was to formulate and evaluate sustained release matrix tablets of Glycopyrrolate and Formoterol. The tablet was prepared by wet granulation Method using Xanthan gum, Karaya gum and HPMC K100M. Compatibility studies between Drug and Excipients showed that DS showed no significant change. The FT-IR studies showed that there is no interaction between the drug and excipients, as all peaks corresponding to different functional groups of pure drug were present in the drug-excipient mixture. All the formulations and their mixture showed acceptable flow properties lik

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3

Rangasamy, Manivannan, Venkata Krishna Reddy Palnati, and Lakshmi Narayana Rao Bandaru. "Formulation development and evaluation of voriconazole sustained release tablets." International Current Pharmaceutical Journal 2, no. 10 (2013): 165–69. http://dx.doi.org/10.3329/icpj.v2i10.16410.

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The present study involves in the formulation and evaluation of sustained release tablets of Voriconazole (250mg). The objective of the present study was to formulate Voriconazole sustained release tablets by wet granulation method by using natural (Xanthan gum, Karaya gum) and semi synthetic polymers (HPMC K100M). Lactose was used as diluting agent, Magnesium stearate was used as a lubricant and Talc was used as a glident. These sustained release tablets can release the drug up to 12 hours in predetermined rate. The formulated powder blend was evaluated for bulk density, tapped density, compr

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4

Ashok Kumar, P., and S. Damodar Kumar. "EFFECT OF HYDROPHILIC POLYMERS ON CONTROLLED RELEASE MATRIX TABLETS OF ACYCLOVIR." INDIAN DRUGS 50, no. 01 (2013): 42–49. http://dx.doi.org/10.53879/id.50.01.p0042.

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Acyclovir was formulated as oral controlled release matrix tablets using natural and synthetic polymers separately or in combinations. Tablets were prepared by direct compression method. The tablets were evaluated to thickness, weight variation test, drug content, hardness, friability and in vitro release studies.All the formulations showed compliance with pharmacopoeal standards. The tablets prepared with various combination of hydroxy propyl methylcellulose (HPMC K100), locust bean gum (LBG) and karaya gum (KG) failed to produce the desired controlled release. Dissolution studies indicated t

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5

Shubham, Solanke* Hemant Sawarkar Aijaz Sheikh Kailash Biyani. "Design And Characterization of Gastroretentive Drug Delivery System of a Model Drug." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 734–37. https://doi.org/10.5281/zenodo.15596005.

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This study focused on developing a gastroretentive drug delivery system (GRDDS) for lamotrigine, an antiepileptic drug, using floating tablets formulated with curdlan gum and hydroxypropyl methylcellulose (HPMC K100M) as matrix-forming polymers, alongside sodium bicarbonate as a gas-generating agent. The objective was to enhance gastric retention and achieve sustained drug release. Eight formulations (F1–F4 with curdlan gum, F5–F8 with HPMC K100M) were prepared via direct compression and evaluated for physicochemical properties, buoyancy, swelling, in-vitro drug release, kinetics,

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6

Soujanya, Anand Kumar Y, and Yashashwini B. "Design, optimization and in vitro characterization of valsartan loaded floating tablets." GSC Biological and Pharmaceutical Sciences 29, no. 3 (2024): 373–85. https://doi.org/10.30574/gscbps.2024.29.3.0433.

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The present work was aim to design and optimize floating drug delivery systems of Valsartan using HPMC K15M, HPMC K100M, Guar gum as polymer and sodium bicarbonate as a gas generating agent. The tablets were prepared by direct compression method. Response surface methodology (RSM) was adapted using Box Behnken Design (BBD) using amount of HPMC K15M (X1), HPMC K100M (X2) and Guar gum (X3) were selected as independent variables, buoyancy time (Y1) and t50 (Y2) selected as dependent variables. All the designed 15 trial batches of formulations were evaluated for precompression, postcompression, dr

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7

Soujanya, Kumar Y. Anand, and B. Yashashwini. "Design, optimization and in vitro characterization of valsartan loaded floating tablets." GSC Biological and Pharmaceutical Sciences 29, no. 3 (2024): 373–85. https://doi.org/10.5281/zenodo.14915723.

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The present work was aim to design and optimize floating drug delivery systems of Valsartan using HPMC K15M, HPMC K100M, Guar gum as polymer and sodium bicarbonate as a gas generating agent. The tablets were prepared by direct compression method. Response surface methodology (RSM) was adapted using Box Behnken Design (BBD) using amount of HPMC K15M (X1), HPMC K100M (X2) and Guar gum (X3) were selected as independent variables, buoyancy time (Y1) and t50 (Y2) selected as dependent variables. All the designed 15 trial batches of formulations were evaluated for precompression, postcompression, dr

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8

Sari, Shelinia Prima, Angi Nadya Bestari, and T. N. Saifullah Sulaiman. "Optimasi Formula Tablet Floating Famotidin Menggunakan Kombinasi Matriks Gum Xanthan dan Hidroksi Propil Metil Selulosa K100M." Majalah Farmaseutik 15, no. 2 (2019): 86. http://dx.doi.org/10.22146/farmaseutik.v15i2.46878.

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Famotidin adalah obat antihistamin H2 yang digunakan dalam pengobatan penyakit tukak lambung (peptic ulcer), tukak duodenal, ataupun keadaan hipersekresi yang patologis. Tablet floating famotidin dapat meningkatkan bioavailabilitas dengan mempertahankan waktu tinggal tablet dalam lambung dan mendekatkan famotidin pada tempat absorpsinya pada lambung bagian atas. Penelitian ini bertujuan untuk mengetahui komposisi optimum HPMC K100M serta gum xanthan dan pengaruh variasi keduanya terhadap sifat fisik granul dan tablet floating famotidin. Pembuatan delapan formula tablet floating famotidin mengg

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9

Djebbar, Mohamed, Nacéra Chaffai, Fatiha Bouchal, and Noureddine Aouf. "Effervescent floating tablets of metformin HCl developed by melt granulation. Part I: Effect of hydrophilic polymer on biopharmaceutical properties." GSC Biological and Pharmaceutical Sciences 6, no. 2 (2019): 052–67. https://doi.org/10.5281/zenodo.4303950.

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In the present study which the aim to evaluate the effect of hydrophilic polymer on the biopharmaceutical properties of metformin hydrochloride floating tablets, we have prepared floating systems using melt granulation, according to effervescent approach. Two hydrophilic polymers are used at various concentrations (10, 12.5, 15 and 17.5%), Acacia gum and hydroxypropylmethylcellulose (HPMC) at three viscosity grades (K4M, K15M and K100M). In addition to the satisfactory physical parameters, the evaluation of buoyancy and <em>in vitro</em> dissolution of floating developed systems reve

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10

Andini, Septia, Siti Sa’diah, and Suci Puspa. "Preparasi dan Karakteristik Floating Tablet Ekstrak Daun Jambu Biji (Psidium guajava L.) dengan Variasi Kombinasi Xanthan Gum dan HPMC." Jurnal Sains dan Kesehatan 4, no. 4 (2022): 370–78. http://dx.doi.org/10.25026/jsk.v4i4.1226.

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Floating drug delivery system (FRDDS) is a new drug delivery system that is intended to prolong the time of drugs in the stomach. One form of the gastroretentive system is a floating tablet, which can float and stay in the stomach for some time. Preparations with this system are suitable for use in drugs that have an action on the stomach. Gastritis is defined as an inflammation or swelling of the inner lining of the stomach. Guava leaves are proven to have active ingredients that can act as anti-ulcers. This study aims to formulate floating tablets and determine the optimal combination of HPM

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