Academic literature on the topic 'KDP crystals'

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Journal articles on the topic "KDP crystals"

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Zhang, Fei Hu, Shao Long Guo, Yong Zhang, and Dian Rong Luan. "Research on the Material Removal Mechanism in Deliquescent Polishing of KDP Crystals." Key Engineering Materials 416 (September 2009): 487–91. http://dx.doi.org/10.4028/www.scientific.net/kem.416.487.

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A new ultraprecision machining technology for KDP crystals, deliquescent polishing technology for KDP crystals, is presented. On the basis of analyzing the definitions of deliquescence, the dissolution experiment of KDP crystal’s surface was conducted. Through the experiment, the material removal mechanism in deliquescent polishing of KDP crystals is proposed, and the deliquescent polishing device for KDP crystals is described. Based on the material removal mechanism in deliquescent polishing of KDP crystals, the deliquescent polishing experiment of KDP crystal was carried out, the experimental result has verified the validity, feasibility and effectiveness of the material removal mechanism.
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Guo, Shao Long, Fei Hu Zhang, Yong Zhang, and Dian Rong Luan. "Research on Deliquescent Polishing Fluid for KDP Crystals." Materials Science Forum 626-627 (August 2009): 53–58. http://dx.doi.org/10.4028/www.scientific.net/msf.626-627.53.

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The characteristics and principle of deliquescent polishing technology for potassium dihydrogen phosphate (KDP) crystals are introduced, and the performance requirements of deliquescent polishing fluid for KDP crystals are proposed. The main components of the deliquescent polishing fluid for KDP crystals were selected according to these performance requirements. Through uniformity experiment, stability experiment and fluidity experiment, uniformity, stability and fluidity of deliquescent polishing fluid for KDP crystals prepared using the selected components were tested. Through deliquescent polishing experiment of KDP crystal, polishing performance of deliquescent polishing fluid compounded using the selected components was tested. The material removal rate of the KDP crystal in the deliquescent polishing experiment was 6.03μm/min, and the surface roughness of the KDP crystal after deliquescent polishing was 4.857nm. The experimental results show that the compounded deliquescent polishing fluid for KDP crystals has good polishing performance and can reach the requirements.
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Zhang, Cheng Long, Ping Fa Feng, Z. J. Wu, and Ding Wen Yu. "Experimental Investigation on Surface Roughness of KDP Crystal Pro-Cessed with Rotary Ultrasonic Face Milling." Key Engineering Materials 499 (January 2012): 223–28. http://dx.doi.org/10.4028/www.scientific.net/kem.499.223.

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KDP crystal is a good nonlinear optical and electro-optical crystal material. However, KDP crystal is considered to be one of the most difficult machining materials due to its inherent properties. This paper presents a preliminary experimental study on surface roughness of KDP crystal processed with rotary ultrasonic face milling. The study shows that the process variables (spindle speed, feedrate, and milling depth) have significant influence on the surface roughness in processing KDP crystal. It discusses the effects of the mechanical properties of KDP crystal on the processing performance. The experimental investigation reveals that the rotary ultrasonic face milling method can obtain smoother surface, which means the method is available for processing KDP crystals with a proper machining conditions. This preliminary research affords a guiding significance for precision processing KDP crystals.
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Phan, Vinh Trung, Anh Thi Quynh Le, and Dat Thanh Huynh. "Growth and characterization of KDP single crystals by Sankaranarayanan-Ramasamy (SR) method." Science and Technology Development Journal - Natural Sciences 1, T4 (December 31, 2017): 88–94. http://dx.doi.org/10.32508/stdjns.v1it4.489.

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Pure KDP single crystals were studied extensively since the 1930s because they could be grown easily to reach a large size, of their low cost and piezoelectric property. Since then, many applications of the KDP crystal have been developed such as the electro-optic modulation, the optical switch (Q-Switch) and the frequency of laser converter through the second-, thirdorder nonlinear effects. In response to these applications, the high-quality KDP single crystals are required. The common method of growing KDP crystal is the temperature lowering, in which a KDP seed is placed in a supersaturated solution. The disadvantage of this method is the spontaneous appearance of crystalline clusters at the bottom of the container which retard the growth of the main crystal. Since the 2010s, Sankaranarayanan and Ramasamy have proposed a new method of growing crystal by designing the Y-shaped solution container. In this study, the KDP single crystals were grown by the SR method. These crystals have better quality, fewer defects, higher hardness and density, and especially material saving compared to the ones prepared by the traditional methods.
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Zhang, Yong, Ning Hou, Liang-Chi Zhang, and Qi Wang. "Elastic-plastic-brittle transitions of potassium dihydrogen phosphate crystals: characterization by nanoindentation." Advances in Manufacturing 8, no. 4 (September 2, 2020): 447–56. http://dx.doi.org/10.1007/s40436-020-00320-3.

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AbstractPotassium dihydrogen phosphate (KDP) crystals are widely used in laser ignition facilities as optical switching and frequency conversion components. These crystals are soft, brittle, and sensitive to external conditions (e.g., humidity, temperature, and applied stress). Hence, conventional characterization methods, such as transmission electron microscopy, cannot be used to study the mechanisms of material deformation. Nevertheless, understanding the mechanism of plastic-brittle transition in KDP crystals is important to prevent the fracture damage during the machining process. This study explores the plastic deformation and brittle fracture mechanisms of KDP crystals through nanoindentation experiments and theoretical calculations. The results show that dislocation nucleation and propagation are the main mechanisms of plastic deformation in KDP crystals, and dislocation pileup leads to brittle fracture during nanoindentation. Nanoindentation experiments using various indenters indicate that the external stress fields influence the plastic deformation of KDP crystals, and plastic deformation and brittle fracture are related to the material’s anisotropy. However, the effect of loading rate on the KDP crystal deformation is practically negligible. The results of this research provide important information on reducing machining-induced damage and further improving the optical performance of KDP crystal components.
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Aswathappa, Sivakumar, Eniya Palaniyasan, Sahaya Jude Dhas Sathiyadhas, Kalyana Sundar Jayaperumal, Sivaprakash Paramasivam, Arumugam Sonachalam, and Martin Britto Dhas Sathiyadhas Amalapushpam. "Shock wave induced defect engineering on structural and optical properties of pure and dye doped potassium dihydrogen phosphate crystals." Zeitschrift für Kristallographie - Crystalline Materials 235, no. 6-7 (July 28, 2020): 193–202. http://dx.doi.org/10.1515/zkri-2020-0017.

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AbstractBased on the importance of the shock recovery experiments, the authors report the structural and optical properties of pure and 0.001 M dye-doped potassium dihydrogen phosphate (KDP) crystals for virgin and shock wave loaded samples. Rhodamine B and Methylene blue dyes are selected as dopants to be doped with KDP crystal for the present investigation. The test crystals of pure and doped KDP crystals are grown by slow evaporation technique and cut and polished crystals of (200) face are used for the present investigation. Table-top pressure driven shock tube is utilized for the shock wave generation and the used functional Mach number is 1.7. Virgin and shock wave loaded test crystals’ surface morphology, structural properties and optical transmissions are observed using optical microscope, powder X-ray diffractometer and UV-Visible spectrometer, respectively. Crystalline nature and optical transmission of pure and doped KDP crystals are found to have reduced by the impact of shock waves. It occurs due to the enhancement of defect concentration on the surface of the test crystals. From the observed results, we assert that the pure KDP crystal is relatively more stable to shock wave induced damage compared to doped KDP crystals as reflected by structural and optical studies.
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Qin, Mengfei, Xinguang Xu, Guangwei Yu, Bo Wang, and Wenyong Cheng. "Rapid Growth of KDP Crystals in the [101] Direction." Crystals 10, no. 2 (February 12, 2020): 108. http://dx.doi.org/10.3390/cryst10020108.

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KDP crystals have important applications in inertial confinement fusion. However, during the rapid growth of large-sized KDP crystals, inclusion is prone to occur. The existence of inclusion will lead to the reduction of crystal quality and utilization and even the end of the growth process. The generation of inclusion is related to the interaction between the crystal and the liquid flow. In this paper, we changed the hydrodynamic condition around the crystal by changing the crystal growth direction and achieve the rapid growth of [101] direction KDP crystals without inclusion at a low rotation rate. The utilization of the crystal was improved and the crystal has good optical transmittance, crystalline perfection and laser damage threshold. Meanwhile, atomic force microscopy was used to study the characteristics and changes of the micromorphology on (100) and (101) faces under different levels of supersaturation. The analysis results show that under high supersaturation, the uneven distribution of solutes and insufficient flow rate cause local macrosteps, two-dimensional step platforms and two-dimensional cores to form irregular structures with large slopes, thereby reducing the stability of the interface. This study will help to better understand the effect of the interaction between liquid flow and crystals on the formation of inclusion and guide the growth of KDP crystals.
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Khan, Imran, S. Kalainathan, M. I. Baig, Mohd Shkir, S. Alfaify, H. A. Ghramh, and Mohd Anis. "Linear-nonlinear optical, dielectric and surface microscopic investigation of KH2PO4 crystal to uncover the decisive impact of dopant glycine." Materials Science-Poland 36, no. 4 (December 1, 2018): 662–67. http://dx.doi.org/10.2478/msp-2018-0073.

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AbstractPresent investigation has been started to perform the comparative study of pure and glycine doped KH2PO4 (KDP) single crystals grown by most commercial slow solvent evaporation technique. The grown crystals were subjected to single crystal X-ray diffraction analysis to determine their structural parameters. The linear optical studies of pure and glycine doped KDP crystal have been undertaken within 200 nm to 1100 nm wavelength range by means of UV-Vis studies. The enhancement in second harmonic generation (SHG) efficiency of glycine doped KDP crystal has been determined using a standard Kurtz-Perry powder test. The dielectric measurements have been carried out to explore the impact of glycine dopant on dielectric constant and dielectric loss of KDP crystal. The surface growth habitat and etch pit density of glycine doped KDP crystal have been evaluated using the results of microscopic etching studies. In light of obtained results the suitability of glycine doped KDP crystal for device applications has been discussed.
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Salo, V. I. "Rapidly grown KDP crystals." Semiconductor Physics, Quantum Electronics and Optoelectronics 3, no. 2 (March 21, 2000): 200–202. http://dx.doi.org/10.15407/spqeo3.02.200.

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Wang, Jing He, Ming Jun Chen, Shen Dong, H. X. Wang, J. H. Zhang, and Wen Jun Zong. "Critical Cutting Condition for Brittle-Ductile Transition of KDP Crystals in Ultra-Precision Machining." Key Engineering Materials 329 (January 2007): 409–14. http://dx.doi.org/10.4028/www.scientific.net/kem.329.409.

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In this paper, mechanical characteristics of KDP crystal anisotropy are analysed theoretically. Vickers indentation experiments are adopted to validate the variation rule of hardness and fracture toughness in different orientation of KDP crystal plane (100), and a model to calculate critical cutting thickness of brittle-ductile transition is proposed for the KDP crystals. The result shows that, on the crystal plane (100), the minimum value of critical cutting thickness of KDP crystal in brittle-ductile transition appears in the direction [110], but the maximum appears in the direction [010]. Finally, the ultra-precision machining of KDP crystal is performed, and the results agree well with the theoretical conclusions. Super-smooth surface with a roughness RMS of 6.6nm is reached as machined in the crystal direction [010], and 11.2nm to the direction [110].
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Dissertations / Theses on the topic "KDP crystals"

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Gouldieff, Céline. "Etude de l'interaction laser-matière en régime nanoseconde sous irradiations multiples : application aux composants optiques pour l’UV." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4328.

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Les travaux portent sur l’endommagement laser en régime nanoseconde aux longueurs d’onde 355 nm et 266 nm. L'objectif de cette étude est de comprendre et d'analyser les processus mis en jeu lors de l'endommagement laser en surface et en volume de matériaux optiques, massifs ou en couches minces, lors de tirs répétés. Dans ce contexte, un banc d'endommagement laser a été entièrement mis en place et automatisé. Il permet d'analyser la résistance et le vieillissement de ces composants sous irradiation UV à des fréquences de tir de 50Hz, pour un grand nombre de tirs et de relever de façon systématique les paramètres du test les plus importants (profiles spatiaux et énergies des impulsions, images du site avant et après dommage). Pour une meilleure compréhension des phénomènes physiques conduisant à la fatigue des matériaux en tirs laser répétés, un modèle a été développé afin de discriminer les effets statistiques (dus au grand nombre de tirs impliqués) de modifications du matériau sous flux UV. Ce modèle a été validé expérimentalement dans le cas de la silice synthétique étudiée en volume. En ce qui concerne les couches minces, une étude multi-paramètres de la tenue au flux UV de mixtures d'oxydes a été menée, en partenariat avec le Laser Zentrum Hannover (LZH, Allemagne). Ces matériaux ont en effet un comportement complexe et encore mal connu, en particulier en tirs répétés. Enfin, une partie du travail de thèse est consacrée à la caractérisation non-destructive de cristaux de KDP par photoluminescence pompée dans l'UV, réalisée dans le contexte du laser MégaJoule en collaboration avec le CEA Le Ripault (Monts)
The work is devoted to laser-induced damage in the nanosecond regime at the wavelengths of 266 nm and 355 nm. The goal of this study is to understand and to analyze the processes taking place during multi-pulse irradiation causing laser-damage, on the surface and in the bulk of massive or thin-films optical materials. To this end, a laser-damage experiment was entirely set up and automated. It allows analyzing the laser-damage resistance and the ageing of these components under UV irradiation at a pulse repetition rate of 50 Hz and for a high number of laser pulses and to record systematically the most important test parameters (spatial beam profiles, energies, images of the site before and after irradiation).To better understand the physical phenomena leading to fatigue effects in the materials under multiple pulse irradiation, a model was developed allowing the discrimination of statistical effects (due to the high number of shots) from material modifications under UV irradiation. This model was confirmed by testing synthetic fused silica irradiated in the bulk. Concerning thin-film coated components, oxide mixtures were studied in collaboration with the Laser Zentrum Hannover (LZH, Germany) using a multi-parameter approach. These materials show indeed a complex behavior and remain poorly known, in particular under multi-pulse irradiation. Finally, a part of the work is dedicated to the non-destructive characterization of KDP crystals by UV-pumped photoluminescence, realized in the framework of the MegaJoule project, in collaboration with CEA Le Ripault (Monts, France)
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Hamberg, Anna, and Sandrine Idlas. "Characterization of domain gratings in KTP and RKTP crystals for second harmonic generation." Thesis, KTH, Skolan för teknikvetenskap (SCI), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-104028.

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Lasers are used in a vast range of applications ranging from eye surgery to devices formeasuring air pollution. Most of these applications require specific wavelengths that cannot be obtained by regular lasers. Therefore it is important to be able to convert the wavelength of the laser to the desired wavelength for a specific application. This is achieved by using nonlinear optical crystals in which an incoming light frequency can be converted into another. Due to the material’s chromatic dispersion there is a phase mismatch between the incoming and generated light, which prevents a net increase of the generated light’s power. A solution to this problem is the creation of domain gratings in ferroelectric crystals, which compensates for the phase mismatch between the interacting photons. However, the conversion efficiency will depend on the quality of the grating. In this study, we have characterized KTiOPO4 and Rb‐doped KTiOPO4 ferroelectric crystals in terms of their efficiency to convert infrared light to blue light. This conversion efficiency has been correlated to the domain structure and the quality of the grating. We have found that the homogeneity of the grating and the existence of damage on the crystal’s optical surfaces have a strong impact on the conversion efficiency.
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Karlsson, Håkan. "Fabrication of periodically poled crystals from the KTP family and their applications in nonlinear optics." Doctoral thesis, KTH, Physics, 1999. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2860.

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Quasi-phasematched (QPM) nonlinear optical frequencyconversion is a powerful tool in the development of new lasersources, by providing high conversion efficiency and largeflexibility in terms of output wavelengths.

QPM structures are preferably implemented in bulk crystalsbe periodic electric field poling. Bulk crystal interactionsareneeded for high power generation. In this thesis, methodsfor achieving periodic poling in materials from the KTP familyare developed. A novel technique for optical monitoring of thepoling is also described. These materials combine highnonlinearity with wide transmission range, good power handlingcapability, and high damage thresholds. Their low coercivefield also allows thick crystals to be poled into largeaperture QPM devices. On the other hand, the high and varyingionic conductivity in these materials has been identified asimportant factor complicating the poling process.

Periodically poled QPM structures have been fabricated influx grown KTP, RTA and RTP. Up to 3 mm thick crystals of RTAand KTP have been periodically poled, which are the thickestperiodically poled crystals ever reported.

The periodically poled crystals have been used in varioustypes of type-I QPM frequency conversion experiments, includingboth SHG (Second Harmonic Generation) and OPO (OpticalParametric Oscillation). Continuous wave powers exceeding 700mW in the blue, over 65% conversion efficiency for pulsedgeneration of green light and up to 17 mJ pulses at 1.58µm have been obtained. The shortest wavelength generatedis 390 nm using a QPM period of 2.95 µm. The possibilityof obtaining type-II QPM frequency conversion has also beendemonstrated.

Keywords:quasi-phasematching, KTP, nonlinear optics,frequency conversion, periodic electric field poling,ferroelectrics, lasers, optical parametric oscillators.

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HUANG, ZHEN-TANG, and 黃振堂. "Improved method of solution crystal growth of TGS and KDP." Thesis, 1990. http://ndltd.ncl.edu.tw/handle/49806686220373632200.

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Huang, Chih-hsien, and 黃至賢. "The K.P theory in photonic crystals." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/99543151447214830858.

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碩士
國立交通大學
光電工程所
91
Using the K.P theory into photonic crystals (PCs), the photon excites an inertial mass form the periodic background. The phenomenon that the light trapped in the defect is similar to the particle trapped in the potential. Any arbitrary small defect will bind a state in 1-D defect, but a finite disorder is needed to bind a state in 2-D or 3-D defects. When we calculate the properties of the defects, the effective inertial mass can be gotten from the experiments or the simulation results from numerical methods of bulk PCs. Introducing the parameter into two-band model of K.P theory in the heterosturcture of PCs, the envelop function and the bound state energy can be solving quite correctly no matter in 1-D PCs or 2-D PCs. The K.P method provides an analytic method to solve the Maxwell’s equation in PCs, and by the method, we can predict and explain the trapping phenomenon of the PCs with defect whereas other numerical simulation methods just can tell us just a simulation result.
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Kixmüller, Dorthe. "Transcriptional regulation and physiological importance of the kdp-system from the halophilic archaeon Halobacterium salinarum." Doctoral thesis, 2012. https://repositorium.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-2012040310105.

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The high affinity, ATP-dependent K+ uptake system KdpFABC of Halobacterium salinarum, is highly induced under K+ limitation. In contrast to the well-characterized Kdp system in Escherichia coli, in which the kdpFABC genes are transcriptionally regulated by the sensor kinase/response regulator system KdpD/KdpE, transcriptional regulation of the kdp genes in H. salinarum was unknown due to the absence of halobacterial homologues of KdpD/KdpE. Furthermore, the physiological relevance of the KdpFABC K+ uptake system of H. salinarum was puzzling, since hypersaline habitats usually comprise K+ concentrations which do not induce kdp expression. In order to analyze the regulation of kdp gene expression, it was essential to gain information about the transcriptional unit(s) involved. Northern blotting, primer extension analysis and real-time RT-PCR revealed the presence of a polycistronic leaderless kdpFABCQ transcript with a putative kdp terminator or at least a potential mRNA processing site downstream of kdpQ. Furthermore, promoter truncation studies verified the so far only predicted basal transcription elements together with an upstream-located operator sequence. Since deletions of this putative operator sequence did not lead to a constitutive expression, a further component has to be involved in the regulation of the kdpFABCQ genes. However, truncation and scanning mutagenesis analyses of the kdp promoter as well as translational fusions of a halophilic beta-galactosidase to the kdp promoter excluded an additional regulatory element up- or downstream of the basal transcription elements and in the kdp-coding region. These results lead to speculations of multiple basal transcription factors to be involved. Furthermore, an inducible expression vector (shuttle vector) was constructed based on the promoter of the kdpFABCQ operon due to its, K+-sensitive features. Inducible expression systems are yet not available for H. salinarum. The resulting, replicating vector pKIX is functional and enables a K+-dependent expression from the kdp promoter with rather high induction ratios of 50-fold. Expression levels could further be improved by plasmid- and additional chromosomally encoded kdpQ and mutations generated in the kdp promoter. Since transcript levels from pKIX were found to be independent of differential target genes, the general application of pKIX as an inducible expression system is strongly supported and pKIX could, thus, be made accessible to the scientific community. To decipher the physiological relevance of the halobacterial Kdp system, H. salinarum was encountered to desiccation stress and salt crystal (halite) entombment. Halite crystals grown under non-inducing K+ concentrations with entombed strains of H. salinarum and H. salinarum deleted in the kdpFABCQ genes revealed a significantly reduced survival rate of the deletion strain upon recultivation. Additionally, a kdpFABCQ-inducing desiccation stress could already be determined on agar plates under non-limiting K+ concentrations. Furthermore, the cell morphology of H. salinarum entrapped in halite crystals resembled that of H. salinarum grown under K+-limiting conditions. Therefore, the Kdp system promotes survival of H. salinarum under desiccation stress. Furthermore, the Kdp system could be identified as at least one of the systems important for long-term survival of H. salinarum in halite.
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Sukhoy, Kostyantyn. "Generation of green second harmonic radiation in LBO, BiBO, KTP, and PPLN crystals using passively Q-switched sub-nanosecond microchip laser." 2011. http://hdl.handle.net/1993/4744.

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A sub-nanosecond green laser source has big demand in such fields like spectroscopy, micromachining, fluorescence imaging, and laser displays. Most often green light is produced by frequency doubling of pulsed laser sources based on Nd3+-ion or Yb3+-ion doped gain media that oscillate in the near-IR range. For creating compact and relatively small source of green light suitable for broad type of applications a passively Q-switched Nd:YAG microchip laser (Teem Photonics) operating at 1064 nm with 6.9 kHz repetition rate was chosen. It delivers 560 ps long pulses with 10 μJ energy, corresponding to an average output power of 69 mW. Crystals of BiBO, KTP, LBO, and PPLN were chosen for frequency doubling. Main goal of this work was to study the characteristics of these crystals under similar experimental conditions and to select the most efficient one for this task. To optimize second harmonic generation (SHG) process, different focusing conditions were used during the experiments. In this work we measured the second harmonic output power as a function of the incident power, beam profile for fundamental and second harmonic radiation for all crystals, and second harmonic output power as a function of temperature for PPLN crystal. Crystal of PPLN was found to be the most suitable for SHG process and produced it with up to 60% conversion efficiency.
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Chang, Yi-Wei, and 張毅偉. "(一)Crystal Structures of the 70-kDa Heat Shock Proteins in Domain Disjoining Conformation(二)Crystal Structure of Saccharomyces cerevisiae Get4-Get5 Complex Involved in Tail-anchored Membrane Protein Targeting." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/59002916470518505392.

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博士
國立清華大學
生物資訊與結構生物研究所
98
(Part1) The 70-kDa heat shock proteins (Hsp70s) are highly conserved ATP-dependent molecular chaperones composed of an N-terminal nucleotide binding domain (NBD) and a C-terminal protein substrate binding domain (SBD) in a bilobate structure. Interdomain communication and nucleotide-dependent structural motions are critical for Hsp70 chaperone functions. Our understanding of these functions remains elusive due to insufficient structural information of functionally intact Hsp70s in different chaperone cycle states. We report here the crystal structures of DnaK from Geobacillus kaustophilus HTA426 bound with ADP-Mg2+-Pi at 2.37 Å and 70-kDa heat shock cognate protein from Rattus norvegicus bound with ADP-Pi at 3.5 Å. The NBD and SBD in these structures are significantly separated from each other and they may be corresponding to the ADP-bound conformation. Moreover, a Trp reporter was introduced at the potential interface region between NBD and interdomain linker of GkDnaK to probe the environmental changes. The result of fluorescence measurement further supports that the substrate binding enhanced domain disjoining behavior for Hsp70 chaperone family. (Part2) The tail-anchored (TA) proteins are a typical class of membrane proteins, which present a single transmembrane domain (TMD) located near their C-termini. By anchoring the single TMD into the phospholipid bilayer surrounding cellular organelles, the N-terminal cytosolic portion of TA proteins can be properly arranged to cytosol for particular functional purposes. Get3, Get4 and Get5 in Saccharomyces cerevisiae participate in the insertion of tail-anchored proteins into the endoplasmic reticulum membrane. We elucidated the interaction between Get4 and Get5 and investigated their interaction with Get3. Based on crystallographic studies, Get4 and Get5 formed a tight complex, suggesting that they constitute subunits of a larger complex. The Get4 structure shows an overall oblong shape and uses its C-terminal part to interact with Get5. Yeast two-hybrid experiment revealed that Get4 mediates the communication between Get3 and Get5 by interact with these two proteins through its different bisections.
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Chou, Chia-Cheng, and 周家丞. "(1) The crystal structure of phosphoglucose isomerase / autocrine motility factor / neuroleukin complexed with its carbohydrate phosphate inhibitors suggests its substrate / receptor recognition. (2) The crystal structure of C-terminal 10 kDa subdomain of." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/42715895178074273926.

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博士
國防醫學院
生命科學研究所
89
Abstract (1) Phosphoglucose isomerase catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate. In addition, phosphoglucose isomerase has been shown to have functions equivalent to neuroleukin, autocrine motility factor and differentiation / maturation factor. Here we present the crystal structures of phosphoglucose isomerase complexed with 5-phospho-D-arabinonate and N-bromoacetylethanolamine phosphate at 2.5 A and 2.3 A resolution, respectively. The inhibitors bind to a region within the domains’ interface and interact with a histidine residue (His306) from the other subunit. We also demonstrated that the inhibitors not only affect the enzymatic activity of phosphoglucose isomerase, but can also inhibit the autocrine motility factor induced cell motility of CT-26 mouse colon tumor cells. These results indicate that the substrate and the receptor binding sites of phosphoglucose isomerase and autocrine motility factor are located approximate to each other. Based on these two complex structures, together with biological and biochemical results, we propose a possible isomerization mechanism for phosphoglucose isomerase. The reaction is initiated at (i) the binding of substrate stabilized by the network of hydrogen bonds between the substrate and the active site amino acids. (ii) Lys420 is involved in the opening of the phosphoglucopyranose ring by functioning as a general base. (iii) His306, acting as a general base, extracts the proton from C2. Simultaneously, Glu285 acts as a general acid and donates a proton to the C1 carbonyl oxygen. The concerted action of these two residues transforms the substrate to the cis-enediol intermediate and inaugurates the isomerization step. By reversing their roles in the subsequent step, the carboxylate of Glu285, acting as the base, and the imidazolium of His306, acting as the acid, work on the intermediate to complete the isomerization reaction. Arg202 contributes the interaction of the phosphate group and may lock the substrate in an optimum position for isomerization. (iv) After isomerization, Lys420 performs an acid-catalyzed ring closure reaction, and the product is released from the enzyme. Abstract(2) Heat shock protein 70 (Hsp70) chaperones play an essential role in protein folding by preventing the misfolding and aggregation of folding intermidates, under normal and stressed growth conditions. The heat shock cognate 70 (Hsc70), belongs to Hsp70 family, is constitutely experessed in the cytosol of the mammalian cells. Structurally, Hsc70 and all Hsp70 family shared the same domain structures. The N-terminal 44 kDa domain is an ATPase, and that the C-terminal 30 kDa domain is thought to be responsible for binding of unfolded proteins or nascent polypeptide substrate. The 30 kDa domain can divided into a N-terminal 18 kDa peptide binding subdomain and a C-terminal 10 kDa subdomain. Many evidences suggest that the 10 kDa subdomain may participate the interdomain communication between the ATPase domain and peptide binding subdomain, and the recognition for the accociated proteins to regulate the chaperone function and other specific cellular functions in different Hsp70 family proteins. Here we report the crystal structure of C-terminal 10 kDa subdomain of recombinant rat Rattus norvegicus Hsc70 protein at 3.45A by multiwavelength anomalous dispersion method. The lemon-shaped crystal belongs to the P6122 space group, and the cell dimensions are A=B=117.0 A,C=163.8 A. The electrostatic surface potential and the limits of the space combined with the mutagenesis experiments suggest that the C-terminal subdomain may form a coiled coil or helical boundle structure with the I helix of the ATPase domain by the charge-charge interaction in the absence of ATP and substrate. After the ATP binding, the induced conformational change facilitates the C-terminal subdomain separated from the ATPase domain, and then plays a role to regulate the substrate binding activity or interact with its target proteins.
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Lakomek, Kristina. "Structural characterization of the lysosomal 66.3 kDa protein and of the DNA repair enzyme Mth0212 by means of X-ray crystallography." Doctoral thesis, 2009. http://hdl.handle.net/11858/00-1735-0000-0006-AD5D-B.

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Books on the topic "KDP crystals"

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Rashkovich, L. N. KDP-family single crystals. Bristol, Eng: A. Hilger, 1991.

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Book chapters on the topic "KDP crystals"

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Chernov, A. A., L. N. Rashkovich, I. L. Smol’skii, Yu G. Kuznetsov, A. A. Mkrtchyan, and A. I. Malkin. "Growth of KDP-Group Crystals from Solution." In Growth of Crystals, 43–91. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4615-7125-4_4.

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Bespalov, V. I., V. I. Bredikhin, V. P. Ershov, V. I. Katsman, and S. Yu Potapenko. "Growth Rate Problems of KDP Type Single Crystals." In Growth of Crystals, 123–34. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3660-4_12.

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Rashkovich, L. N., and G. T. Moldazhanova. "Growth Kinetics and Bipyramid-Face Morphology of KDP Crystals." In Growth of Crystals, 69–78. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-1141-6_7.

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Smol’skii, I. L., and N. P. Zaitseva. "Characteristic Defects and Imperfections in KDP Crystals Grown at High Rates." In Growth of Crystals, 173–85. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2379-6_14.

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Kuznetsov, V. A., E. P. Efremova, T. M. Okhrimenko, and A. Yu Klimova. "Growth and Certain Properties of KDP Crystals Affected by pH and Temperature." In Growth of Crystals, 79–87. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-1141-6_8.

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Rashkovich, L. N., and B. Yu Shekunov. "Influence of Impurities on Growth Kinetics and Morphology of Prismatic Faces of ADP and KDP Crystals." In Growth of Crystals, 107–19. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3268-2_10.

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Indira, K., and T. Chitravel. "Synthesis and Spectroscopic Characterization of Pure and l-Arginine Doped KDP Crystals." In Lecture Notes in Mechanical Engineering, 627–35. India: Springer India, 2012. http://dx.doi.org/10.1007/978-81-322-1007-8_58.

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Wang, Jing He, Ming Jun Chen, Shen Dong, H. X. Wang, J. H. Zhang, and Wen Jun Zong. "Critical Cutting Condition for Brittle-Ductile Transition of KDP Crystals in Ultra-Precision Machining." In Advances in Abrasive Technology IX, 409–14. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-416-2.409.

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Gayvoronsky, V. Ya, M. A. Kopylovsky, M. S. Brodyn, A. S. Popov, V. O. Yatsyna, and I. M. Pritula. "Interplay of Quadratic and Cubic Nonlinear Optical Responses in KDP Single Crystals with Incorporated TiO2 Nanoparticles." In Springer Proceedings in Physics, 349–65. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7675-7_24.

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Wang, Sheng-Lai, Xun Sun, and Xu-Tang Tao. "Growth and Characterization of KDP and Its Analogs." In Springer Handbook of Crystal Growth, 759–94. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-74761-1_22.

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Conference papers on the topic "KDP crystals"

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Kuznetsov, V. A., T. M. Okhrimenko, and Miroslawa Rak. "Catalytic effect of the impurities on growth of KAP and KDP crystals." In XII Conference on Solid State Crystals: Materials Science and Applications, edited by Jozef Zmija, Andrzej Majchrowski, Jaroslaw Rutkowski, and Jerzy Zielinski. SPIE, 1997. http://dx.doi.org/10.1117/12.280712.

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Bensouici, A., O. Halimi, A. Chaieb, and M. Sebais. "ZnSe nanocrystals embedded in KDP crystals." In 2008 2nd ICTON Mediterranean Winter (ICTON-MW). IEEE, 2008. http://dx.doi.org/10.1109/ictonmw.2008.4773106.

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Duchateau, Guillaume. "Modeling laser conditioning of KDP crystals." In Laser Damage Symposium XLI: Annual Symposium on Optical Materials for High Power Lasers, edited by Gregory J. Exarhos, Vitaly E. Gruzdev, Detlev Ristau, M. J. Soileau, and Christopher J. Stolz. SPIE, 2009. http://dx.doi.org/10.1117/12.836064.

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Gunning, Mark J., Rafal Ledzion, Piotr Gorski, and Wlodzimierz Kucharczyk. "Quadratic electro-optic effect in KDP-type crystals." In International Conference on Solid State Crystals '98, edited by Andrzej Majchrowski and Jerzy Zielinski. SPIE, 1999. http://dx.doi.org/10.1117/12.342999.

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Piano, E., Gian A. Dall'Aglio, and Alberto Diaspro. "KDP crystal growth from solution studied with Diffrasor technique." In International Conference on Solid State Crystals '98, edited by Andrzej Majchrowski and Jerzy Zielinski. SPIE, 1999. http://dx.doi.org/10.1117/12.342965.

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Chen, Jian, Jingtao Dong, Qi Zhang, and Zhouling Wu. "Three-dimensional photothermal microscopy of KDP crystals." In SPIE Optical Engineering + Applications, edited by Katherine Creath, Jan Burke, and Joanna Schmit. SPIE, 2014. http://dx.doi.org/10.1117/12.2062528.

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Zhang, Weiqing, Yongxing Tang, Xiaolin Liu, Minhua Jiang, Yueqin Le, Jinren Sun, and Zhiya Chen. "Protective coatings for large-sized KDP crystals." In Third International Conference on Thin Film Physics and Applications, edited by Shixun Zhou, Yongling Wang, Yi-Xin Chen, and Shuzheng Mao. SPIE, 1998. http://dx.doi.org/10.1117/12.300645.

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Maunier, C., M. Balas, T. Donval, L. Lamaignère, G. Duchateau, and G. Mennerat. "Self-laser conditioning of KDP and DKDP crystals." In XLIII Annual Symposium on Optical Materials for High Power Lasers, edited by Gregory J. Exarhos, Vitaly E. Gruzdev, Joseph A. Menapace, Detlev Ristau, and M. J. Soileau. SPIE, 2011. http://dx.doi.org/10.1117/12.899184.

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Tkachenko, V. F., M. A. Rom, Vitaly I. Salo, and Marina I. Kolybayeva. "Structural quality of impurity-containing KDP single crystals." In Laser-Induced Damage in Optical Materials: 1997, edited by Gregory J. Exarhos, Arthur H. Guenther, Mark R. Kozlowski, and M. J. Soileau. SPIE, 1998. http://dx.doi.org/10.1117/12.307043.

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Wheeler, Elizabeth K., J. T. McWhirter, Pamela K. Whitman, C. B. Thorsness, James J. De Yoreo, Ian M. Thomas, and M. Hester. "Scatter loss from environmental degradation of KDP crystals." In Laser-Induced Damage in Optical Materials: 1999, edited by Gregory J. Exarhos, Arthur H. Guenther, Mark R. Kozlowski, Keith L. Lewis, and M. J. Soileau. SPIE, 2000. http://dx.doi.org/10.1117/12.379328.

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Reports on the topic "KDP crystals"

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Montesanti, R. C., and S. L. Thompson. A procedure for diamond turning KDP crystals. Office of Scientific and Technical Information (OSTI), July 1995. http://dx.doi.org/10.2172/105024.

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De Yoreo, J., S. Demos, M. Yan, and M. Staggs. Origins of laser damage in crystals of KDP. Office of Scientific and Technical Information (OSTI), May 2000. http://dx.doi.org/10.2172/15005380.

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Atherton, L. J., A. K. Burnham, R. C. Combs, S. A. Couture, J. J. De Yoreo, R. A. Hawley-Fedder, R. C. Montesant, et al. Producing KDP and DKDP crystals for the NIF laser. Office of Scientific and Technical Information (OSTI), September 1999. http://dx.doi.org/10.2172/14145.

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Smith, W., and F. Milanovich. Stimulated RAMAN Scattering Inside KDP Crystal Segments. Office of Scientific and Technical Information (OSTI), September 2014. http://dx.doi.org/10.2172/1165816.

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Smith, W., F. Milanovich, and M. Henesian. Stimulated Raman Scattering Inside KDP Crystal Segments - II. Office of Scientific and Technical Information (OSTI), September 2014. http://dx.doi.org/10.2172/1165793.

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Lupinski, Dominique. Investigating and Supplying Halid Flux-Grown KTP Crystals. Fort Belvoir, VA: Defense Technical Information Center, July 1995. http://dx.doi.org/10.21236/ada298749.

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