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Journal articles on the topic 'Kellgren-lawrence system'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Salama, Ahmed, Kamel Rahouma, and Fatma Elzahraa Mansour. "Knee osteoarthritis automatic detection using U-Net." IAES International Journal of Artificial Intelligence (IJ-AI) 13, no. 2 (2024): 2122. http://dx.doi.org/10.11591/ijai.v13.i2.pp2122-2130.

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Knee osteoarthritis or OA is one of the most common diseases that can affect the elderly and overweight people. OA is occur as the result of wear and tear and progressive loss of articular cartilage. Kellgren-Lawrence system is a common method of classifying the severity of osteoarthritis depends on knee joint width. According to Kellgren-Lawrence, knee osteoarthritis is divided into five classes; one class represents a normal knee and the others represent four levels of knee osteoarthritis. In this work, we aim to automatically detect knee OA according to the Kellgren-Lawrence classification.

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Ahmed, Salama Abdellatif, Hussien Rahouma Kamel, and E. Mansour Fatma. "Knee osteoarthritis automatic detection using U-Net." IAES International Journal of Artificial Intelligence (IJ-AI) 13, no. 2 (2024): 2122–30. https://doi.org/10.11591/ijai.v13.i2.pp2122-2130.

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Knee osteoarthritis or OA is one of the most common diseases that can affect the elderly and overweight people. OA is occurred as the result of wear, tear, and progressive loss of articular cartilage. Kellgren-Lawrence system is a common method of classifying the severity of osteoarthritis depends on knee joint width. According to Kellgren-Lawrence, knee OA is divided into five classes; one class represents a normal knee and the others represent four levels of knee OA. In this work, we aim to automatically detect knee OA according to the Kellgren-Lawrence classification. The proposed system us

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Moon, Ki-Ho. "New View on the Initial Development Site and Radiographic Classification System of Osteoarthritis of the Knee Based on Radiographic Analysis." International Journal of Biomedical Science 8, no. 4 (2012): 233–43. http://dx.doi.org/10.59566/ijbs.2012.8233.

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ntroduction: Radiographic pathology of severe osteoarthritis of the knee (OAK) such as severe osteophyte at tibial spine (TS), compartment narrowing, marginal osteophyte, and subchondral sclerosis is well known. Kellgren-Lawrence grading system, which is widely used to diagnose OAK, describes narrowing-marginal osteophyte in 4-grades but uses osteophyte at TS only as evidence of OAK without detailed-grading. However, kinematically the knee employs medial TS as an axis while medial and lateral compartments carry the load, suggesting that early OAK would occur sooner at TS than at compartment. T

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Linda Pertiwi, Ni Made, and Ni Luh Jaya Kirana. "Conventional Radiography of Grade III Knee Osteoarthritis: A Case Report." International Journal of Research and Review 10, no. 10 (2023): 536–40. http://dx.doi.org/10.52403/ijrr.20231068.

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Introduction: Osteoarthritis (OA) is the most common form of inflammatory joint disease. It occurs most frequently in the knees, hips, the spine (vertebrae), and ankles. Radiological prevalence of knee OA in Indonesia reaches 15.5% in men and 12.7% in women aged between 40-60 years. X-ray imaging is routinely used in clinical practice to confirm knee OA diagnosis and in clinical research to monitor the progression of knee OA. Case report: A 62-year-old female patient presented with knee pain in both knees that had been ongoing for the past 6 months. The pain was described as throbbing and stab

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Ogawa, Ami, Hirotaka Iijima, and Masaki Takahashi. "Identification of Early Knee Osteoarthritis Based on Knee Joint Trajectory during Stair Climbing." International Journal of Environmental Research and Public Health 19, no. 22 (2022): 15023. http://dx.doi.org/10.3390/ijerph192215023.

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Patients with knee osteoarthritis show low stair climbing ability, but a diagnosis of stair performance time is not enough to identify the early stages of knee osteoarthritis. Therefore, we developed an indicator named range of the knee joint trajectory (RKJT) as a kinematic parameter to express more detailed characteristics than stair performance time. To achieve this, we used our developed “IR-Locomotion”, a markerless measurement system that can track the knee joint trajectory when climbing stairs. This study aimed to test whether the RKJT effectively identifies patients with early knee ost

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Sananta, Panji, Nyoman Triska Ariyanti, Dhelya Widasmara, and Eka Noviya Fuzianingsih. "Is there any correlation between physical activity and severity of knee osteoarthritis in secondary referral hospital in Indonesia?" Biomedicine 42, no. 5 (2022): 1014–17. http://dx.doi.org/10.51248/.v42i5.1857.

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Introduction and Aim: Osteoarthritis is a pathological condition of the joints that is degenerative and progressive, affecting two-thirds of people over 65 years of age, with a prevalence of 1.39 million among males and 1.69 million in females. The main clinical manifestation of osteoarthritis is joint pain. The incidence and progression of knee osteoarthritis are strongly influenced by risk factors, consisting of systemic factors including age, sex, hormonal factors, and biomechanical factors such as obesity, physical activity, and muscle weakness. The purpose of this study was to determine i

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Abdelaziz, Hussein, Oury M. Balde, Mustafa Citak, Thorsten Gehrke, Ahmed Magan, and Carl Haasper. "Kellgren–Lawrence scoring system underestimates cartilage damage when indicating TKA: preoperative radiograph versus intraoperative photograph." Archives of Orthopaedic and Trauma Surgery 139, no. 9 (2019): 1287–92. http://dx.doi.org/10.1007/s00402-019-03223-6.

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Sibarani, Jonathan J., Atta Kuntara, and Renaldi P. H. N. Rasyid. "Korelasi antara Usia dan Derajat Osteoartritis Sendi Lutut Berdasarkan Sistem Klasifikasi Kellgren-Lawrence di RSUP Dr. Hasan Sadikin Bandung Tahun 2019-2020." Journal of Medicine and Health 3, no. 1 (2021): 16–25. http://dx.doi.org/10.28932/jmh.v3i1.3218.

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Osteoarthritis is a joint disease that commonly causes disability in the elderly. Thisresearch aimed to find the correlation between age and primary knee osteoarthritis gradeaccording to the Kellgren-Lawrence classification system in patients in the Department ofRadiology of RSUP Dr. Hasan Sadikin Bandung. This research was a cross-sectional study. Thisresearch used Spearman’s correlation method. This research used X-ray results from theDepartment of Radiology of RSHS from 1 January 2019-29 February 2020 (n=67). The grade ofknee osteoarthritis was diagnosed by a radiology consultant of RSHS. T

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Naseem, Sajid, Muhammad Sajid Rafiq Abbasi, Jahangir Anjum, Nadeem Afzal, Zia Kakar, and Komal Aqeel Safdar. "Association between Pain, Functional Impairment and Radiographic Findings in Patients with Osteoarthritis of Knee." Pakistan Journal of Medical and Health Sciences 15, no. 9 (2021): 2544–46. http://dx.doi.org/10.53350/pjmhs211592544.

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Objective: To explore the relationship between pain, functional impairment (disability) and the radiographic findings in patients with osteoarthritis of the knee. Study Design: Cross sectional study Place and Duration of Study: Department of Rhematology, Pakistan Air Force Hospital Islamabad from 1st September 2020 to 28th February 2021 Methodology: One hundred and thirty eight patients of knee joint osteoarthritis were included. Weight bearing antero-posterior and lateral views X-ray for both knees were performed on each patient and Kellgren-Lawrence (KL) system was used to grade the severity

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Ahmad, Ilham Wildan, Lita Diah Rahmawati, and Teddy Heri Wardhana. "Demographic Profile, Clinical and Analysis of Osteoarthritis Patients in Surabaya." Biomolecular and Health Science Journal 1, no. 1 (2018): 34. http://dx.doi.org/10.20473/bhsj.v1i1.8208.

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Introduction: Osteoarthritis is a degenerative joint disease which affects joint cartilage. As many as 80% patients movement are limited and 25% of them can not even perform daily activities. Osteoarthritis is one of the ten most disabling diseases in developed countries. Due to its chronic and progressive nature, socio-economic impacts in many developed and developing countries are enormous. The purpose of this study is to determine the profile of patients with osteoarthritis in the Orthopedic Department of RSUD Dr. Soetomo Surabaya (Dr. Soetomo General Hospital)Method: This is descriptive ob

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Mahum, Rabbia, Saeed Ur Rehman, Talha Meraj, et al. "A Novel Hybrid Approach Based on Deep CNN Features to Detect Knee Osteoarthritis." Sensors 21, no. 18 (2021): 6189. http://dx.doi.org/10.3390/s21186189.

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In the recent era, various diseases have severely affected the lifestyle of individuals, especially adults. Among these, bone diseases, including Knee Osteoarthritis (KOA), have a great impact on quality of life. KOA is a knee joint problem mainly produced due to decreased Articular Cartilage between femur and tibia bones, producing severe joint pain, effusion, joint movement constraints and gait anomalies. To address these issues, this study presents a novel KOA detection at early stages using deep learning-based feature extraction and classification. Firstly, the input X-ray images are prepr

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Park, Hee-Jin, Sam Soo Kim, So-Yeon Lee, et al. "A practical MRI grading system for osteoarthritis of the knee: Association with Kellgren–Lawrence radiographic scores." European Journal of Radiology 82, no. 1 (2013): 112–17. http://dx.doi.org/10.1016/j.ejrad.2012.02.023.

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Patel, Shelain, Fahad S. Hossain, Bruce Paton, and Fares S. Haddad. "The effects of a non-operative multimodal programme on osteoarthritis of the knee." Annals of The Royal College of Surgeons of England 92, no. 6 (2010): 467–71. http://dx.doi.org/10.1308/rcsann.2010.92.6.467.

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INTRODUCTION The purpose of this study was to determine if a multimodal programme including physiotherapy and education could improve the symptoms of osteoarthritis of the knee across various severities of disease. PATIENTS AND METHODS Seventy-two patients with osteoarthritis of the knee confirmed on radiographic evidence were referred over a 13-month period for a lower limb programme which consisted of 12 classes over 6 weeks of group physiotherapy and included education on osteoarthritis, diet and exercise. Six patients went on to have joint arthroplasty at a mean time of 6.5 months with thr

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Liu, Q., H.-B. He, H. Zeng, et al. "Modified trapdoor procedures by surgical dislocation approach to treat chondroblastoma of the femoral head." Bone & Joint Journal 101-B, no. 6 (2019): 732–38. http://dx.doi.org/10.1302/0301-620x.101b6.bjj-2018-1599.r1.

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Aims The aim of this study was to evaluate the efficacy of the surgical dislocation approach and modified trapdoor procedure for the treatment of chondroblastoma of the femoral head. Patients and Methods A total of 17 patients (ten boys, seven girls; mean age 16.4 years (11 to 26)) diagnosed with chondroblastoma of the femoral head who underwent surgical dislocation of the hip joint, modified trapdoor procedure, curettage, and bone grafting were enrolled in this study and were followed-up for a mean of 35.9 months (12 to 76). Healing and any local recurrence were assessed via clinical and radi

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Maheu, E., C. Cadet, G. Baron, et al. "432 INTER- AND INTRA-OBSERVER REPRODUCIBILITY OF THE RADIOGRAPHIC KELLGREN-LAWRENCE SCORING SYSTEM IN HAND OSTEOARTHRITIS (HOA)." Osteoarthritis and Cartilage 17 (September 2009): S230—S231. http://dx.doi.org/10.1016/s1063-4584(09)60453-2.

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Almira Shafa Hendrawan, Cahyo Wibisono Nugroho, Rosy Setiawati, and Paulus Rahardjo. "Correlation between radiologic and clinical features with quality of life in knee osteoarthritis: A Literature Review." Magna Scientia Advanced Research and Reviews 12, no. 2 (2024): 362–71. https://doi.org/10.30574/msarr.2024.12.2.0211.

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Osteotarthritis (OA) is one of the most common inflammatory joint diseases and rheumatic musculoskeletal conditions worldwide. OA is the 11th most disabling disease in the world. Knee OA is the most common joint condition, accounting for 83% of cases out of 4% of the global population. Diagnosing OA typically begins with history taking of patient, physical examinations, and supportive examination guided by the Indonesian Rheumatology Association. WOMAC index is a widely used patient-reported tool to assess pain, stiffness, and physical function in knee OA patients. Additionallly, knee OA is of

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Kini, Raveena R., Prachita Walankar, Vrushali Panhale, Vijaya Krishnan, and Hetvi D. Gala. "Association of isometric hip abductor strength with Kellgren-Lawrence grade among patients with bilateral knee osteoarthritis." Journal of Musculoskeletal Surgery and Research 8 (January 31, 2024): 24–29. http://dx.doi.org/10.25259/jmsr_228_2023.

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Objectives: The degree of knee osteoarthritis (OA) is usually graded with the Kellgren-Lawrence (KL) grading system. Studies have shown the effect of weak hip abductor muscle as a contributory factor to knee OA. However, there is a shortage of literature regarding the association of hip abductor strength with the KL grade. Methods: Individuals diagnosed with bilateral knee OA between the ages 40 and 70 years, who have had a recent knee radiograph and are mobile and willing to participate, were included in the study. A brief demographic and basic screening was done following which the isometric

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Munawar, Asma, Muhammad Mahmood Alam Durrani, M. Waseem Akhtar, et al. "Association Between Pain and Radiological Changes in Patients with Knee Osteoarthritis." Journal of Health and Rehabilitation Research 4, no. 1 (2024): 608–12. http://dx.doi.org/10.61919/jhrr.v4i1.406.

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Background: Knee osteoarthritis (OA) is a leading cause of disability worldwide, characterized by joint degeneration, pain, and functional limitations. Despite the prevalence of knee OA, the relationship between radiographic changes and the severity of pain remains complex. Previous studies have offered conflicting views on the association between structural joint alterations and clinical symptoms. Objective: The aim of this study was to investigate the association between radiographic degenerative changes in the knee, as classified by the Kellgren and Lawrence grading system, and the severity

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ANKITA, ARUN GUNDECHA, and DEVIDAS GANVIR SHYAM. "IMPACT OF OSTEOARTHRITIS ON FRAILTY AMONG INDIVIDUALS IN COMMUNITY-DWELLERS- A CROSS-SECTIONAL STUDY." VIMS Journal of Physical Therapy 1, no. 1 (2019): 19–22. https://doi.org/10.5281/zenodo.3753665.

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Background: The relationship between OA and frailty has been demonstrated by several longitudinal studies, show-ing that these two conditions share important common risk factors and lead to similar consequences, but if and how OA-related pain, in particular, is linked to frailty is unclear.Aim: To study the association of frailty with osteoarthritis in community dwellers. Materials and Methods: 15 Participants were selected between age group of 40-70 and were assessed. Participants were assessed for osteoarthritis according to Kellgren and Lawrence system of classification, and frailty was ass

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Wiradinata, Marcell Jeremy, and Daniel Martomanggolo Wonohadidjojo. "The Effects of Preprocessing Techniques on Nasnetmobile’s Performance for Classifying Knee Osteoarthritis Based on the Kellgren-Lawrence System." Journal of Applied Informatics and Computing 8, no. 2 (2024): 616–22. https://doi.org/10.30871/jaic.v8i2.8713.

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Osteoartritis lutut (KOA) adalah kelainan sendi degeneratif yang ditandai dengan kerusakan progresif tulang rawan pelindung di ujung tulang, yang mengakibatkan nyeri dan keterbatasan mobilitas. Pembelajaran mendalam memberikan pendekatan yang efektif untuk mengklasifikasikan tingkat keparahan KOA; namun, praproses kumpulan data dapat meningkatkan kemanjuran model pembelajaran mendalam. Studi ini menunjukkan pentingnya praproses, khususnya dalam memanfaatkan model NASNetMobile untuk menilai tingkat keparahan KOA melalui gambar sinar-X. Klasifikasi KOA terdiri dari lima tingkat keparahan yang me

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Dr., S. Jati, and V. Champawat Dr. "A midterm analysis of Tibial plateau fractures: functional outcome and incidence of osteoarthritis in 240 cases." Orthopaedic Journal of M P Chapter 23, no. 2 (2017): 16–21. https://doi.org/10.5281/zenodo.3970336.

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Background: Tibial plateau fractures are a risk to the functional integrity of the knee. They are the result of axial compressive forces alone or combined with Varus or valgus stress on the knee joint. Post-traumatic osteoarthritis occurs after traumatic injury to the joint. The presence of residual incongruity at the time of fracture healing could lead to joint stiffness and long-term morbidity, studies have established the restoration of articular congruity as the key principle on the management of these injuries. Despite anatomical joint reconstruction, development of osteoarthritis may sti

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Culvenor, Adam G., Cathrine N. Engen, Britt Elin Øiestad, Lars Engebretsen, and May Arna Risberg. "Defining the presence of radiographic knee osteoarthritis: a comparison between the Kellgren and Lawrence system and OARSI atlas criteria." Knee Surgery, Sports Traumatology, Arthroscopy 23, no. 12 (2014): 3532–39. http://dx.doi.org/10.1007/s00167-014-3205-0.

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Khodzhanov, I. Yu, B. M. Mamasoliev, A. N. Tkachenko, O. A. Khamidov, and D. Sh Mansurov. "Is lower extremity vein pathology a risk factor for the development of osteoarthritis of the knee joint?" Ural Medical Journal 21, no. 2 (2022): 19–25. http://dx.doi.org/10.52420/2071-5943-2022-21-2-19-25.

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The aim of the work was to assess the relationship between venous insufficiency and osteoarthritis of the knee joint. Materials and Methods. The study included 214 knee joints from April 2018 to March 2021 in 107 subjects (19 men, 88 women), mean age of patients was 54.6 ± 8.6 years (range, 40 to 73 years). The study group included 61 patients diagnosed with knee osteoarthritis; the control group included 46 healthy volunteers without knee joint disease complaints. Demographic and clinical characteristics of all study participants were taken into account. The venous system of the lower extremi

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Mayich, D. Joshua, Ellie Pinsker, Michael S. Mayich, Walter Mak, and Timothy R. Daniels. "An Analysis of the Use of the Kellgren and Lawrence Grading System to Evaluate Peritalar Arthritis Following Total Ankle Arthroplasty." Foot & Ankle International 34, no. 11 (2013): 1508–15. http://dx.doi.org/10.1177/1071100713495379.

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Maheu, E., P. Ravaud, G. Baron, et al. "433 IMPROVEMENT OF THE REPRODUCIBILITY OF THE RADIOGRAPHIC KELLGREN-LAWRENCE (KL) SCORING SYSTEM IN HAND OSTEOARTHRITIS (HOA) USING A NEW KL SCORING SYSTEM AID." Osteoarthritis and Cartilage 18 (October 2010): S193—S194. http://dx.doi.org/10.1016/s1063-4584(10)60460-8.

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Kobayashi, S., M. Simic, A. Peduto, M. Fransen, K. Refshauge, and E. Pappas. "Clinical grading of patellofemoral osteoarthritis severity: intra- and inter- rater reliability for a magnetic resonance imaging-based kellgren and lawrence system." Osteoarthritis and Cartilage 24 (April 2016): S312—S313. http://dx.doi.org/10.1016/j.joca.2016.01.563.

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Kang, Minchae, Suyeon Seo, Hyewon Lee, and Min-Woo Han. "Knee Measurement System with Osteoarthritis Levels Using Artificial Cartilage and Skeletons." Biomimetics 9, no. 3 (2024): 166. http://dx.doi.org/10.3390/biomimetics9030166.

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Knee osteoarthritis (OA), also known as degenerative arthritis, is a disease characterized by irreversible changes in the cartilage and bones comprising the joints, resulting in pain, impaired function, and deformity. Furthermore, independent of natural aging, the rate of change in joint cartilage has increased in recent years, which is mainly attributed to environmental factors. The rising incidence of knee-related disorders emphasizes the importance of analyzing the morphology and kinematics of knee structure. This study introduces a knee measurement system designed to replicate the motions

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Wang, Yifan, Xianan Wang, Tianning Gao, Le Du, and Wei Liu. "An Automatic Knee Osteoarthritis Diagnosis Method Based on Deep Learning: Data from the Osteoarthritis Initiative." Journal of Healthcare Engineering 2021 (September 27, 2021): 1–10. http://dx.doi.org/10.1155/2021/5586529.

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Osteoarthritis (OA) is the most common form of arthritis. According to the evidence presented on both sides of the knee bones, radiologists assess the severity of OA based on the Kellgren–Lawrence (KL) grading system. Recently, computer-aided methods are proposed to improve the efficiency of OA diagnosis. However, the human interventions required by previous semiautomatic segmentation methods limit the application on large-scale datasets. Moreover, well-known CNN architectures applied to the OA severity assessment do not explore the relations between different local regions. In this work, by i

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YAMAZAKI, H., S. UCHIYAMA, Y. HATA, N. MURAKAMI, and H. KATO. "Extensor Tendon Rupture Associated with Osteoarthritis of the Distal Radioulnar Joint." Journal of Hand Surgery (European Volume) 33, no. 4 (2008): 469–74. http://dx.doi.org/10.1177/1753193408090098.

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Non-rheumatoid osteoarthritis of the distal radioulnar joint can cause extensor tendon rupture. We analysed the radiographic morphology of the distal radioulnar joint to identify the risk factors for this complication. Forty-one wrist X-rays of 37 patients with extensor tendon rupture caused by distal radioulnar joint osteoarthritis were evaluated retrospectively for the severity of osteoarthritis by the Kellgren/Lawrence scoring system. Measurements were obtained from posteroanterior views. All but one wrist had severe osteoarthritic changes exceeding grade 3. The radiographic features that w

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Ruiyun, Qiu, Siti Khatijah Nor Abdul Rahim, Nursuriati Jamil, and Raseeda Hamzah. "DualVitOA: A dual vision transformer-based model for osteoarthritis grading using x-ray images." IAES International Journal of Artificial Intelligence (IJ-AI) 14, no. 2 (2025): 925. https://doi.org/10.11591/ijai.v14.i2.pp925-932.

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Knee osteoarthritis (OA) is a primary factor contributing to reduced activity and physical impairment in older individuals. Early identification and treatment of knee OA can assist patients in delaying the advancement of the condition. Currently, knee OA is detected early using X-ray images and assessed based on the Kellgren-Lawrence (KL) grading system. Doctors' assessments are subjective and can vary among different doctors. The automatic knee OA grading and diagnosis can assist doctors and help doctors reduce their workload. A new novel network called dual-vision transformer (ViT) OA is pro

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Qiu, Ruiyun, Khatijah Nor Abdul Rahim Siti, Jamil Nursuriati, and Hamzah Raseeda. "DualVitOA: A dual vision transformer-based model for osteoarthritis grading using x-ray images." IAES International Journal of Artificial Intelligence (IJ-AI) 14, no. 2 (2025): 925–32. https://doi.org/10.11591/ijai.v14.i2.pp925-932.

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Knee osteoarthritis (OA) is a primary factor contributing to reduced activity and physical impairment in older individuals. Early identification and treatment of knee OA can assist patients in delaying the advancement of the condition. Currently, knee OA is detected early using X-ray images and assessed based on the Kellgren-Lawrence (KL) grading system. Doctors' assessments are subjective and can vary among different doctors. The automatic knee OA grading and diagnosis can assist doctors and help doctors reduce their workload. A new novel network called dual-vision transformer (ViT) OA is pro

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Letaeva, M. V., M. V. Koroleva, T. A. Raskina, O. S. Malyshenko, Yu V. Averkieva, and E. V. Usova. "Results of a prospective 6-year observational study of the efficacy and safety of a bioactive concentrate of small marine fish in senile patients with knee osteoarthritis and multimorbidity." Modern Rheumatology Journal 15, no. 4 (2021): 56–62. http://dx.doi.org/10.14412/1996-7012-2021-4-56-62.

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Objective: to evaluate the efficacy and safety of Alflutop therapy in elderly patients (75–90 years old) with knee osteoarthritis (OA) and multimorbidity based on the results of a prospective 6-year follow-up.Patients and methods. The study included 38 elderly women with knee OA (according to ACR criteria, 1986) stage II–III by Kellgren–Lawrence grading system, with pain ≥40 mm by visual analogue scale (VAS), who needed to take non-steroidal anti-inflammatory drugs (NSAIDs). Alflutop was administered as 1 ml intramuscular injections 20 consecutive days with a 6-month interval (12 courses). The

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Sharaby, Mohamed M. F., and Mohamed Abuheif. "Consequences of sagittal malalignment following reconstruction of complex tibial plateau fractures." Egyptian Orthopaedic Journal 58, no. 2 (2023): 112–18. http://dx.doi.org/10.4103/eoj.eoj_2_23.

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Abstract Purpose Changes of posterior tibial slope following complex tibial plateau fractures have not been fully evaluated in the literature. Some studies indicated that arthritic changes that occur following tibial plateau fracture were more correlated to deformity and instability rather than articular surface step-off. The aim of this study was to evaluate the midterm clinical effects following changes in the posterior slope that might be associated with reconstruction of complex tibial plateau fractures. Patients and methods This retrospective cohort study was carried out on 112 patients o

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Sukhikh, Stanislav, Olga Babich, Alexander Prosekov, Nikolai Patyukov, and Svetlana Ivanova. "Future of Chondroprotectors in the Treatment of Degenerative Processes of Connective Tissue." Pharmaceuticals 13, no. 9 (2020): 220. http://dx.doi.org/10.3390/ph13090220.

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Osteoarthritis is one of the most common diseases of the connective tissue of the elderly. It was found that most epidemiological studies used the Kellgren and Lawrence system for classification of osteoarthritis, which indicates one of the 5 degrees (0–4) of osteoarthritis in various joints according to the radiographic atlas. It has been proven that chondroprotectors are represented by the following active substances: chondroitin sulfate, glucosamine sulfate or hydrochloride, hyaluronic acid, glycosaminoglycans, extraction preparations from animal or plant raw materials. The sources of raw m

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Li, Zhan-Chun, Guang-Qi Cheng, Kong-Zu Hu, et al. "Correlation of synovial fluid HMGB-1 levels with radiographic severity of knee osteoarthritis." Clinical & Investigative Medicine 34, no. 5 (2011): 298. http://dx.doi.org/10.25011/cim.v34i5.15673.

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Purpose: This study measured high-mobility group box 1 (HMGB-1) levels in serum and synovial fluid (SF) in patients with primary knee osteoarthritis (OA) and correlated these levels with radiographic disease severity. Methods: Seventy-eight OA patients and 30 controls were enrolled in this study. All OA patients were scored according to the Kellgren-Lawrence (KL) grading system. HMGB-1 levels were measured by enzyme-linked immunosorbent assay (ELISA). Results: SF HMGB-1 levels were significantly higher in knee OA patients, compared with controls (P < 0.01). Moreover, SF HMGB-1 levels were p

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Hariyanto, Hori, John Butar Butar, Gatot Susilo Lawrence, FX Budhianto Suhadi, and Andi Husni Tanra. "Association Between Plasma Beta-endorphin and WOMAC Score in Female Patients with Knee Osteoarthritis." Indonesian Biomedical Journal 4, no. 2 (2012): 107. http://dx.doi.org/10.18585/inabj.v4i2.169.

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BACKGROUND: β-endorphin plays a role in the descending pain control in the central nervous system. Central sensitization may be involved in the generating and maintenance of osteoarthritis (OA) pain. However, the correlation between β-endorphin and pain severity in OA has shown conflicting results. The aim of this study was to investigate the association between plasma β-endorphin and the severity of the disease. METHODS: This study was an observational cross-sectional study carried out on 60 female subjects with knee OA who fulfilled the inclusion criteria. Plasma β-endorphin was measured by

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Umbel, Benjamin D., Devon Myers, Benjamin C. Taylor, John A. Buchan, and Anthony J. Melaragno. "The Intercalary Fragment in Posterior Malleolus Fractures: Characterization and Significance." Foot & Ankle Orthopaedics 7, no. 1 (2022): 2473011421S0006. http://dx.doi.org/10.1177/2473011421s00062.

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Category: Trauma Introduction/Purpose: Methods of fixation in ankle fractures involving the posterior malleolus have become increasingly scrutinized. With the increase in computed tomography (CT), an intercalary fracture fragment (ICF) adjacent to the posterior malleolus has often been described. Treatment of this intercalary comminution remains controversial. The primary goal of this study was to compare clinical and radiographic outcomes in patients who had direct reduction and fixation of this fragment compared to those where the ICF was removed or not reduced prior to posterior malleolus f

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Khmel, O.S., and V.V. Rodionova. "Heart rate variability in patients with hypertension combined with osteoarthrosis under the impact of antihypertensive therapy." Medicni perspektivi 22, no. 2 (2017): 71–78. https://doi.org/10.26641/2307-0404.2017.2.109831.

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Objective: to investigate the heart rate variability in patients with HT and OA under the influence of antihypertensive therapy. Materials and Methods: The study involved 60 persons, main group – 25 patients with HT stage II, 2<sup>nd</sup> degree, combined with knee OA of the II stage according to the Kellgren-Lawrence. The group of comparison consisted of 20 patients with HT stage II, 2<sup>nd</sup> degree. The control group consisted of 15 almost healthy individuals. During the study patients received antihypertensive therapy: Amlodipine 5 mg and Lisinopril 5 mg 1 time per d

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Wu, Christopher, Nobuei Fukui, Yen-Kuang Lin, et al. "Comparison of Robotic and Conventional Unicompartmental Knee Arthroplasty Outcomes in Patients with Osteoarthritis: A Retrospective Cohort Study." Journal of Clinical Medicine 11, no. 1 (2021): 220. http://dx.doi.org/10.3390/jcm11010220.

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Robotic-arm-assisted unicompartmental knee arthroplasty (RUKA) was developed to increase the accuracy of bone alignment and implant positioning. This retrospective study explored whether RUKA has more favorable overall outcomes than conventional unicompartmental knee arthroplasty (CUKA). A total of 158 patients with medial compartment osteoarthritis were recruited, of which 85 had undergone RUKA with the Mako system and 73 had undergone CUKA. The accuracy of component positioning and bone anatomical alignment was compared using preoperative and postoperative radiograph. Clinical outcomes were

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Sun, Jian-Min, Liang-Zhi Sun, Jun Liu, Bao-hui Su, and Lin Shi. "Serum Interleukin-15 Levels Are Associated with Severity of Pain in Patients with Knee Osteoarthritis." Disease Markers 35 (2013): 203–6. http://dx.doi.org/10.1155/2013/176278.

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Background.Inflammation plays a crucial role in the development and progression of osteoarthritis (OA). Interleukin-15 (IL-15) is a well-known proinflammatory cytokine.Objective.We aimed at evaluating the relationship between serum IL-15 levels and the severity of pain as well as radiographic progression in patients with knee OA.Methods.Two hundred and twenty-six OA patients and 106 controls were enrolled in this study. The symptomatic/radiological severity of OA was assessed by the Western Ontario McMaster University Osteoarthritis Index- (WOMAC-)pain scores/Kellgren-Lawrence (KL) grading sys

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Verron, Romain, Lucie Zhang, Hélène Bisseriex, et al. "SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma." Bioengineering 10, no. 11 (2023): 1276. http://dx.doi.org/10.3390/bioengineering10111276.

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Platelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction was assessed by a specific questionnaire named SATMED-Q©, which explores six different dimensions of a given treatment. In addition, pain and function were assessed thanks to VAS pain, WOMAC, and IKDC scores. Responders were identified through the OMERACT-OARSI criteria. We observed excellent satis

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Hassan, Syeda Nida, Mudassir Khalil, Humayun Salahuddin, Rizwan Ali Naqvi, Daesik Jeong, and Seung-Won Lee. "KOC_Net: Impact of the Synthetic Minority Over-Sampling Technique with Deep Learning Models for Classification of Knee Osteoarthritis Using Kellgren–Lawrence X-Ray Grade." Mathematics 12, no. 22 (2024): 3534. http://dx.doi.org/10.3390/math12223534.

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One of the most common diseases afflicting humans is knee osteoarthritis (KOA). KOA occurs when the knee joint cartilage breaks down, and knee bones start rubbing together. The diagnosis of KOA is a lengthy process, and missed diagnosis can have serious consequences. Therefore, the diagnosis of KOA at an initial stage is crucial which prevents the patients from Severe complications. KOA identification using deep learning (DL) algorithms has gained popularity during the past few years. By applying knee X-ray images and the Kellgren–Lawrence (KL) grading system, the objective of this study was t

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Rooney, Edward M., Fred T. Finney, Paul Talusan, James R. Holmes, and David Walton. "Mid Term 5-Year Follow Up of a Novel Algorithm for Non-Operative Weber B Ankle Fractures." Foot & Ankle Orthopaedics 4, no. 4 (2019): 2473011419S0036. http://dx.doi.org/10.1177/2473011419s00366.

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Category: Ankle, Ankle Arthritis, Trauma Introduction/Purpose: It is important to understand which isolated fibular fractures require surgical intervention. Several different radiographic guidelines have been used to interpret and predict stability of the injured ankle. Holmes et al previously described a novel algorithm used to assess stability and the ability to treat the stable injuries non-operatively. The one year results demonstrated favorable outcomes of these non-operative patients, however there is a question about the durability of these results and whether these patients developed p

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Ural, İbrahim Halil, Tomris Duymaz, and Levent Özgönenel. "The Effect of Kinesiotaping Implementation After Anterior Cruciate Ligament Reconstruction." Orthopaedic Journal of Sports Medicine 5, no. 2_suppl2 (2017): 2325967117S0009. http://dx.doi.org/10.1177/2325967117s00097.

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Objective: The main aim of this study was to measure effects of kinesiotaping on pain and range of motion in the conservative treatment of postoperative anterior cruciate ligament(ACL) rupture. Material-Methods: A total of 26 patients(24 women, 2 men) who had unilateral ACL rupture 64.46±9.00 years old(46-81years), 13 had physiotherapy only(mean age 64.46±9.35 years),13 had physiotherapy and kinesiotape(mean age 64.46±9.01 years).The patients in both groups received physiotherapy program (ultrasound with 1 MHz, 1W/cm2 during 5minutes; CPM; strength exercise for quadriceps muscle and cold pack

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Yamada, Junichi, Koji Akeda, Norihiko Takegami, Tatsuhiko Fujiwara, Akinobu Nishimura, and Akihiro Sudo. "Novel elemental grading system for radiographic lumbar spondylosis in a population based-cohort study of a Japanese mountain village." PLOS ONE 17, no. 6 (2022): e0270282. http://dx.doi.org/10.1371/journal.pone.0270282.

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Purpose Lumbar radiography is a primary screening tool for lumbar spondylosis (LS). Kellgren-Lawrence (KL) classification is widely used to evaluate LS; however, it cannot individually evaluate each radiographic feature. The purpose of this study was to 1) evaluate radiographic LS using a novel elemental grading system and 2) investigate the relationship between the grades of radiographic LS and low back pain (LBP) in a population-based cohort study. Methods A total of 260 (75 men, 185 women; mean age, 71.5 ± 8.7 years) participants were included in this study. Participants were divided into t

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Kuila, Pritam Kalyan, Rishov Hazra, Arshad Ahmed, and Rajiv Roy. "Correlation between clinical, radiological and arthroscopic findings in cases of osteoarthritis of knee joint." International Journal of Research in Medical Sciences 12, no. 5 (2024): 1606–11. http://dx.doi.org/10.18203/2320-6012.ijrms20241248.

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Background: Osteoarthritis (OA) is the most common degenerative joint disorder and a major public health problem throughout the world. The knees are the most commonly affected joints. In view of multiple conflicting reports in the literature the present study was undertaken to study the correlation amongst radiological, arthroscopic and pain findings in knee OA patients to facilitate early and precise diagnosis leading to appropriate and timely treatment. Methods: Total 53 (39 female and 14 male) cases of primary OA were screened and selected for our study. Apley’s pain score equated to Visual

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JORDAN, JOANNE M., CHARLES G. HELMICK, JORDAN B. RENNER, et al. "Prevalence of Hip Symptoms and Radiographic and Symptomatic Hip Osteoarthritis in African Americans and Caucasians: The Johnston County Osteoarthritis Project." Journal of Rheumatology 36, no. 4 (2009): 809–15. http://dx.doi.org/10.3899/jrheum.080677.

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Objective.To report contemporary estimates of the prevalence of hip-related osteoarthritis (OA) outcomes in African Americans and Caucasians aged ≥ 45 years.Methods.Weighted prevalence estimates and their corresponding 95% confidence intervals for hip symptoms, radiographic hip OA, symptomatic hip OA, and severe radiographic hip OA were calculated using SUDAAN® for age, race, and sex subgroups among 3068 participants (33% African Americans, 38% men) in the baseline examination (1991–97) of The Johnston County Osteoarthritis Project, a population-based study of OA in North Carolina. Radiographi

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Saito, Motoo, Hiromu Ito, Akinori Okahata, et al. "Ultrasonographic Changes of the Knee Joint Reflect Symptoms of Early Knee Osteoarthritis in General Population; The Nagahama Study." CARTILAGE 13, no. 1 (2022): 194760352210774. http://dx.doi.org/10.1177/19476035221077403.

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Objective Radiographic changes in knee osteoarthritis (OA) are not always associated with symptoms, especially in its early stages. Ultrasonography (US) can detect early changes in the knee joint, but the changes that reflect symptoms have not been fully elucidated. This study aimed to identify US-detectable changes in the knee that are often associated with knee symptoms and demonstrate the feasibility of early diagnosis in symptomatic knee OA using US. Design In this cross-sectional community-based study, 1,667 participants aged ≥60 years (1,103 women [66%]) were included. All participants c

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Yang, Jung Ho, Jae Hyeon Park, Seong-Ho Jang, and Jaesung Cho. "Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model." Annals of Rehabilitation Medicine 44, no. 6 (2020): 415–27. http://dx.doi.org/10.5535/arm.20071.

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Objective To present new classification methods of knee osteoarthritis (KOA) using machine learning and compare its performance with conventional statistical methods as classification techniques using machine learning have recently been developed.Methods A total of 84 KOA patients and 97 normal participants were recruited. KOA patients were clustered into three groups according to the Kellgren-Lawrence (K-L) grading system. All subjects completed gait trials under the same experimental conditions. Machine learning-based classification using the support vector machine (SVM) classifier was perfo

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Schmal, Hagen, Gian M. Salzmann, Elia R. Langenmair, Ralf Henkelmann, Norbert P. Südkamp, and Philipp Niemeyer. "Biochemical Characterization of Early Osteoarthritis in the Ankle." Scientific World Journal 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/434802.

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Purpose.Reliable data aboutin vivoregulation of cytokines in early ankle osteoarthritis (OA) are still missing.Methods.49 patients with a mean age of33±14years undergoing an arthroscopy of the ankle with different stages of chronic OA were prospectively included in a clinical trial. Lavage fluids were analyzed by ELISA. Additionally, clinical parameters and scores (FFI, CFSS, and AOFAS) were evaluated and supplemented by the Kellgren Lawrence Score (KLS) and the ankle osteoarthritis scoring system (AOSS).Results.ICRS grading of cartilage damage, previous operations, and duration of complains w

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