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Journal articles on the topic 'Ketene-imine reaction'

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1

Domingo, Luis R., Mar Ríos-Gutiérrez, and José A. Sáez. "Unravelling the mechanism of the ketene-imine Staudinger reaction. An ELF quantum topological analysis." RSC Advances 5, no. 47 (2015): 37119–29. http://dx.doi.org/10.1039/c5ra03438h.

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2

Filatov, Vadim, Maksim Kukushkin, Juliana Kuznetsova, et al. "Synthesis of 1,3-diaryl-spiro[azetidine-2,3′-indoline]-2′,4-diones via the Staudinger reaction: cis- or trans-diastereoselectivity with different addition modes." RSC Advances 10, no. 24 (2020): 14122–33. http://dx.doi.org/10.1039/d0ra02374d.

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3

Mukerjee, Arya K., Gangadhar J. Sanjayan, and Krishnan Ravikumar. "Reaction of methylphthalimidoketene with benzylidene- and cinnamylideneanilines: structure and configuration of the products." Canadian Journal of Chemistry 73, no. 4 (1995): 614–17. http://dx.doi.org/10.1139/v95-079.

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Methylphthalimidoketene reacts with cinnamylideneanilines to give tetrahydrooxazin-6-ones exclusively, whereas with benzylideneaniline it also forms β-lactam. Configurations are based on X-ray studies. Keywords: β-lactam, tetrahydro-1,3-oxazin-5-ones, ketene–imine reactions, cycloaddition of methylphthalimidoketene, 3-phthaloylamino-3-methylazetidin-2-one.
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4

Zarei, Maaroof. "One-step Synthesis of β-lactams Using Cyanuric Fluoride". Journal of Chemical Research 37, № 1 (2013): 25–27. http://dx.doi.org/10.3184/174751912x13545429290478.

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Cyanuric fluoride works as an efficient acid activator reagent for the direct [2+2] ketene–imine cycloaddition of substituted acetic acids and imines in a one-pot synthesis under mild conditions. The yields are good to excellent and the reaction conditions are mild, simple and efficient.
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5

Yadav, Ram Naresh, Ashok Kumar Srivastava та Bimal Krishna Banik. "Microwave-Induced Bismuth Nitrate-Catalyzed Michael Reaction of 3-Amino β-Lactams with Enones". Asian Journal of Chemistry 32, № 2 (2019): 233–36. http://dx.doi.org/10.14233/ajchem.2020.22168.

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Microwave-induced bismuth nitrate-catalyzed reaction of 3-amino β-lactams with unsaturated ketones is performed in order to obtain substituted amino β-lactams. Amino β-lactams were obtained through the strategy of [2+2] ketene-imine cycloaddition followed by deprotection of phthalimido β-lactams with ethylene diamine.
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6

Assfeld, X., J. A. Sordo, J. González, M. F. Ruiz-López, and T. L. Sordo. "Electrostatic solvent effect on the ketene-imine cycloaddition reaction." Journal of Molecular Structure: THEOCHEM 287 (November 1993): 193–99. http://dx.doi.org/10.1016/0166-1280(93)87222-y.

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7

Yoshimura, Fumihiko, Hiroki Saito, Taiki Abe, and Keiji Tanino. "Nucleophilic Addition of Alkanenitriles to Aldehydes via N-Silyl Ketene Imines Generated In Situ." Synlett 28, no. 14 (2017): 1816–20. http://dx.doi.org/10.1055/s-0036-1588424.

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Upon treatment with triisopropylsilyl trifluoromethanesulfonate and 2,2,6,6-tetramethylpiperidine, alkanenitriles undergo direct addition to aldehydes under mild non-basic neutral conditions to provide triisopropylsilyl ethers of β-hydroxy nitriles in good yield. The reaction proceeds through generation of an N-silyl ketene imine intermediate in situ from the alkanenitrile followed by nucleophilic addition of the intermediate to the aldehyde.
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8

Palomo, Claudio, Jesus M. Aizpurua, Iñaki Ganboa та Mikel Oiarbide. "Asymmetric Synthesis of β-Lactams by Staudinger Ketene-Imine Cycloaddition Reaction". European Journal of Organic Chemistry 1999, № 12 (1999): 3223–35. http://dx.doi.org/10.1002/(sici)1099-0690(199912)1999:12<3223::aid-ejoc3223>3.0.co;2-1.

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9

Fabio, Romano Di, Giuseppe Alvaro, Barbara Bertani, and Simone Giacobbe. "Straightforward synthesis of new tetrahydroquinoline derivatives." Canadian Journal of Chemistry 78, no. 6 (2000): 809–15. http://dx.doi.org/10.1139/v00-079.

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To identify novel classes of glycine antagonists, compounds potentially useful as neuroprotective after stroke, novel substituted tetrahydroquinoline derivatives, satisfying the key pharmacophoric requirements for glycine antagonists, were designed. To explore the SAR of these compounds an efficient synthetic route was set up exploiting the outstanding reactivity of suitable N-aryl imine derivatives. In particular an allylmetalation reaction or the addition of bis(trimethyldisilyl)ketene acetals allowed the preparation of versatile intermediates which were smoothly transformed into the desired
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10

Sordo, J. A., Javier Gonzalez, and T. L. Sordo. "An ab initio study on the mechanism of the ketene-imine cycloaddition reaction." Journal of the American Chemical Society 114, no. 15 (1992): 6249–51. http://dx.doi.org/10.1021/ja00041a055.

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11

Nagao, Yoshimitsu, Toshio Kumagai, Sachiko Takao, et al. "New methylseleno-promoted ketene-imine cycloaddition reaction. A simplified stereoselective synthesis of penam." Journal of Organic Chemistry 51, no. 24 (1986): 4737–39. http://dx.doi.org/10.1021/jo00374a051.

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12

Palomo, Claudio, та Jesus Maria Aizpurua. "Asymmetric synthesis of 3-amino-β-lactamsvia Staudinger ketene-imine cycloaddition reaction (review)". Chemistry of Heterocyclic Compounds 34, № 11 (1998): 1222–36. http://dx.doi.org/10.1007/bf02256803.

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13

Palomo, Claudio, Jesus M. Aizpurua, Inaki Ganboa та Mikel Oiarbide. "ChemInform Abstract: Asymmetric Synthesis of β-Lactams by Staudinger Ketene-Imine Cycloaddition Reaction". ChemInform 31, № 6 (2010): no. http://dx.doi.org/10.1002/chin.200006261.

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14

M, Heravi; Majid, A. Rezvanian, and F. Alinaghian. "Metal-Free Assemblage of Four C−N and Two C−C Bonds via a Cascade Five Component Diastereoselective Synthesis of Pyrido[1,2-a]Pyrimidines." ChemistrySelect 3, no. 41 (2018): 11565–68. https://doi.org/10.1002/slct.201802481.

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An efficient heteroannulation synthesis of N-fused, pyrido[1,2-a]pyrimidines was successfully achieved via a sequential, one-pot five-component reaction, involving primary amines, diketene (DK), differently substituted aromatic aldehydes, nitro ketene dithioacetal and propanediamine in ethanol at 70 &deg;C. This new protocol constructs two rings through the formation of four C&ndash;N and two C&ndash;C bonds via a one pot sequential reaction involving ring-opening/ Knoevenagel condensation, /nucleophilic substitution (SN)/ Michael addition followed by imine&minus;enamine tautomerization and fi
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15

Lu, Nan, Chengxia Miao та Xiaozheng Lan. "Theoretical investigation on diastereoselective [2+2] cycloaddition and Pd-catalyzed enantioselective [3+2] cycloaddition for synthesis of cis-β-lactam and exo-furobenzopyranone". Thermal Science and Engineering 7, № 1 (2024): 5949. http://dx.doi.org/10.24294/tse.v7i1.5949.

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The mechanism is investigated for Wolff rearrangement/Staudinger [2+2] cycloaddition cascade and Pd-catalyzed, decarboxylative, formal [3+2] cycloaddition. Wolff rearrangement of 3-diazotetramic acid is determined to be rate-limiting step generates cyclic acyl ketene. The interaction of ketene with imine firstly results in zwitterion followed by conrotatory cyclization giving major cis-β-lactam. For synthesis of s-VECs, the epoxidation−cyclization cascade and hydrolysis give precursor of better performing exocyclic derivative. The reaction with 3-cyanochromone includes decarboxylation, nucleop
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16

Ram, Naresh Yadav, Banik Indrani та Krishna Banik Bimal. "Microwave-assisted novel stereoselective synthesis of bis-β-lactams with 2,7-phenanthrenyl imines". Journal of Indian Chemical Society Vol. 95, Nov 2018 (2018): 1377–80. https://doi.org/10.5281/zenodo.5652757.

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Department of Chemistry, Faculty of Engineering &amp; Technology, Veer Bahadur Singh Purvanchal University, Jaunpur-222 003, Uttar Pradesh, India Department of Chemistry, University of Texas-Pan American,1201 W. University Dr., Edinburg, TX 78539, USA The University of Texas M. D. Anderson Cancer Center, Department of Molecular Pathology, 1515 Holcombe Blvd, Houston, TX 77030, USA Community Health System of South Texas, 3135 South Sugar Road, Edinburg, TX 78539, USA E-mail: bimalbanik10@gmail.com, bimal.banik@chsst.org <em>Manuscript received 01 October 2018, accepted 02 November 2018</em> Mic
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17

Fujisawa, Tamotsu, Akinori Shibuya, Daisuke Sato та Makoto Shimizu. "Stereoselective Synthesis of Monocyclic β-Lactam Related to a Carmonam Precursor via Ketene-Imine Reaction". Synlett 1995, № 10 (1995): 1067–68. http://dx.doi.org/10.1055/s-1995-5187.

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18

Cossío, Fernando P., Ana Arrieta, and Miguel A. Sierra. "The Mechanism of the Ketene−Imine (Staudinger) Reaction in Its Centennial: Still an Unsolved Problem?" Accounts of Chemical Research 41, no. 8 (2008): 925–36. http://dx.doi.org/10.1021/ar800033j.

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19

Palomo, Claudio, та Jesus Maria Aizpurua. "ChemInform Abstract: Asymmetric Synthesis of 3-Amino-β-lactams via Staudinger Ketene-Imine Cycloaddition Reaction". ChemInform 30, № 16 (2010): no. http://dx.doi.org/10.1002/chin.199916305.

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20

Ram, Naresh Yadav, Kumar Singh Amarendra, Banik Indrani та Krishna Banik Bimal. "Microwave-induced stereospecific synthesis of trans 3-phenylthio β-lactams". Journal of Indian Chemical Society Vol. 96, Oct 2019 (2019): 1359–63. https://doi.org/10.5281/zenodo.5642753.

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Department of Chemistry, Faculty of Engineering and Technology, Veer Bahadur Singh Purvanchal University, Jaunpur-222 003, Uttar Pradesh India Department of Chemistry, University of Texas-Pan American, 1201 W. University Dr., Edinburg, TX 78539, USA The University of Texas-M. D. Anderson Cancer Center, Department of Molecular Pathology, 1515 Holcombe Blvd, Houston, TX 77030, USA Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Prince Mohammad Bin Fahd University, Al Khobar, Kingdom of Saudi Arabia <em>E-mail:</em> bimalbanik10@gmail.com; bbanik@pmu.edu.sa
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21

Hosseini, Fahimeh S., and Mohammad Bayat. "Synthesis of New 5-amino-7-(aryl)-1,2,3,7-tetrahydro-8-nitroimidazo[1,2-a]pyridine- 6-carboxamide and 6-amino-2,3,4,8-tetrahydro-9-nitro-8-(aryl)-1H-pyrido[1,2- a]pyrimidine-7-carboxamide Derivatives." Current Organic Synthesis 15, no. 7 (2018): 982–88. http://dx.doi.org/10.2174/1570179415666180709121950.

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Aim and Objectives: Development of simple synthetic routes for widely used organic compounds from readily available reagents is one of the major tasks in organic chemistry. Therefore, new approaches for increasing the molecular diversity of simple starting materials, are needed. Herein, an efficient synthesis of imidazo[1,2-a]pyridine, pyrido[1,2-a]pyrimidine and pyrido[1,2-a][1,3]diazepine derivatives is described. Materials and Methods: A one-pot, multi-component reaction of nitro ketene aminal derived from the addition of various 1,n-diamines to 1,1-bis(methylthio)-2-nitroethene with cyanoa
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22

del Pozo, Carlos, Alberto Macías, Fernando López-Ortiz, Miguel Ángel Maestro, Eduardo Alonso та Javier González. "Diastereo- and Enantioselective Synthesis of Novelβ-Lactam-Containing 1,4-Benzodiazepines through a Ketene−Imine Cycloaddition Reaction". European Journal of Organic Chemistry 2004, № 3 (2004): 535–45. http://dx.doi.org/10.1002/ejoc.200300447.

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23

Hassan, Sangar A., Media N. Abdullah та Dara M. Aziz. "Synthesis of New Series Bis-3-Chloro-β-Lactam Derivatives from Symmetrical Bis-Schiff Bases as Effective Antimicrobial Agents with Molecular Docking Studies". Science Journal of University of Zakho 9, № 3 (2021): 128–37. http://dx.doi.org/10.25271/sjuoz.2021.9.3.830.

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Endeavoring to find a new type of antimicrobial agents, a new sequence of bis-Schiff bases and bis-3-cholro-β-lactams are synthesized. An astonishing class of strained compounds is part of the symmetrical bis-Schiff bases that has widespread applications and building blocks for the combination of bis-3-cholro-β-lactams antibiotics. Bis-3-cholro-β-lactams are synthesized through (Staudinger) [2+2] ketene-imine cycloaddition reaction. Structures of the produced compounds are deduced by 1H, 13C-NMR, and FT-IR spectroscopies. All produced compounds are shown moderate to good antimicrobial activity
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24

FUJISAWA, T., A. SHIBUYA, D. SATO та M. SHIMIZU. "ChemInform Abstract: Stereoselective Synthesis of a Monocyclic β-Lactam Related to a Carmonam Precursor via Ketene-Imine Reaction." ChemInform 27, № 11 (2010): no. http://dx.doi.org/10.1002/chin.199611300.

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25

Gandhi, Divyani, Ayushi Sethiya, Dinesh Kr Agarwal, Prakash Prajapat, and Shikha Agarwal. "Design, Synthesis and Antimicrobial Study of Novel 1-(1,3-benzothiazol-2- yl)-3-chloro-4H-spiro[azetidine-2,3'-indole]-2',4(1'H)-diones Through Ketene– imine Cycloaddition Reaction." Letters in Organic Chemistry 17, no. 2 (2020): 141–48. http://dx.doi.org/10.2174/1570178616666190705153224.

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: The present study deals with the synthesis of novel 1-(1,3-benzothiazol-2-yl)-3-chloro-4Hspiro[ azetidine-2,3'-indole]-2',4(1'H)-dione derivatives from the reaction of 3-(1,3-benzothiazol-2- ylimino)-1,3-dihydro-2H-indol-2-one derivatives with chloroacetyl chloride in the presence of triethylamine (TEA). The mechanism involved simple acid or base catalysed reaction through the formation of Schiff base followed by cyclisation via ketene–imine cycloaddition reaction. All synthesized compounds were characterized by FT-IR, 1H-NMR, 13C-NMR, and elemental analysis. The antimicrobial activities of
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26

Truong, Thanh N. "Solvent Effects on Structure and Reaction Mechanism: A Theoretical Study of [2 + 2] Polar Cycloaddition between Ketene and Imine." Journal of Physical Chemistry B 102, no. 40 (1998): 7877–81. http://dx.doi.org/10.1021/jp9816263.

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27

Fang, De-Cai, and Xiao-Yuan Fu. "Ab initio studies on the mechanism of the cycloaddition reaction between ketene imine and formaldehyde — catalytic and solvent effects." Chemical Physics Letters 259, no. 3-4 (1996): 265–70. http://dx.doi.org/10.1016/0009-2614(96)00797-x.

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28

Venturini, Alessandro, and Javier González. "A CASPT2 and CASSCF Approach to the Cycloaddition of Ketene and Imine: A New Mechanistic Scheme of the Staudinger Reaction." Journal of Organic Chemistry 67, no. 25 (2002): 9089–92. http://dx.doi.org/10.1021/jo026188h.

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29

Kaboudin, Babak, та Mohammad Afsharinezhad. "Synthesis of a Novel Class of β-Lactam Derivatives of 1-Aminophosphonates by Staudinger Ketene-Imine [2+2]-Cycloaddition Reaction". Synthesis 2010, № 20 (2010): 3504–8. http://dx.doi.org/10.1055/s-0030-1257889.

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30

Assfeld, X., M. F. Ruiz-lopez, J. Gonzalez, R. Lopez, J. A. Sordo, and T. L. Sordo. "Theoretical analysis of the role of the solvent on the reaction mechanisms: One-step versus two-step ketene-imine cycloaddition." Journal of Computational Chemistry 15, no. 5 (1994): 479–87. http://dx.doi.org/10.1002/jcc.540150502.

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31

Lynch, Joseph E., Stephen M. Riseman, William L. Laswell, et al. "Mechanism of an acid chloride-imine reaction by low-temperature FT-IR: .beta.-lactam formation occurs exclusively through a ketene intermediate." Journal of Organic Chemistry 54, no. 16 (1989): 3792–96. http://dx.doi.org/10.1021/jo00277a011.

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32

Kaboudin, Babak, та Mohammad Bagher Afsharinezhad. "ChemInform Abstract: Synthesis of a Novel Class of β-Lactam Derivatives of 1-Aminophosphonates by Staudinger Ketene-Imine [2 + 2]-Cycloaddition Reaction." ChemInform 42, № 5 (2011): no. http://dx.doi.org/10.1002/chin.201105092.

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33

Nimbalkar, Urja, Julio Seijas, Rachna Borkute, et al. "Ultrasound Assisted Synthesis of 4-(Benzyloxy)-N-(3-chloro-2-(substitutedphenyl)-4-oxoazetidin-1-yl) Benzamide as Challenging Anti-Tubercular Scaffold." Molecules 23, no. 8 (2018): 1945. http://dx.doi.org/10.3390/molecules23081945.

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A series of ten novel derivatives of 4-(benzyloxy)-N-(3-chloro-2-(substituted phenyl)-4-oxoazetidin-1-yl) benzamide 6a–j were synthesized in good yield from the key compound 4-(benzyloxy)-N′-(substituted benzylidene) benzo hydrazide, called Schiff ’s bases 5a–j, by Staudinger reaction ([2 + 2] ketene-imine cycloaddition reaction) with chloro acetyl chloride in the presence of catalyst tri ethylamine and solvent dimethyl formamide (DMF), by using ultra-sonication as one of the green chemistry tools. All the synthesised compounds were evaluated for in vitro anti-tubercular activity against Mycob
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34

Shimizu, M. "Switchover of the Diastereoselectivity Induced by a Simple Selection of Titanium(IV) Halides in the Addition Reaction of Silyl Ketene Acetals to a Chiral Imine." Tetrahedron Letters 36, no. 29 (1995): 5227–30. http://dx.doi.org/10.1016/00404-0399(50)0978l-.

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35

SHIMIZU, M., K. KUME, and T. FUJISAWA. "ChemInform Abstract: Switchover of the Diastereoselectivity Induced by a Simple Selection of Titanium(IV) Halides in the Addition Reaction of Silyl Ketene Acetals to a Chiral Imine." ChemInform 26, no. 43 (2010): no. http://dx.doi.org/10.1002/chin.199543126.

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36

Palomo, Claudio, Fernando P. Cossio, Jose M. Odiozola, Mikel Oiarbide, and Jesus M. Ontoria. "Preparation of 3-alkyl .beta.-lactams via the ketene imine cycloaddition reaction using .alpha.-(phenylthio)alkanoyl halides as starting materials: application to the synthesis of (.+-.)-carbapenem building blocks and related compounds." Journal of Organic Chemistry 56, no. 14 (1991): 4418–28. http://dx.doi.org/10.1021/jo00014a017.

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37

GEORG, G. I., and V. T. RAVIKUMAR. "ChemInform Abstract: Stereocontrolled Ketene-Imine Cycloaddition Reactions." ChemInform 25, no. 25 (2010): no. http://dx.doi.org/10.1002/chin.199425299.

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38

PALOMO, C., F. P. COSSIO, J. M. ODIOZOLA, M. OIARBIDE та J. M. ONTORIA. "ChemInform Abstract: Preparation of 3-Alkyl β-Lactams via the Ketene - Imine Cycloaddition Reaction Using α-(Phenylthio)alkanoyl Halides as Starting Materials: Application to the Synthesis of (.+-.)-Carbapenem Building Blocks and Related Compounds." ChemInform 22, № 47 (2010): no. http://dx.doi.org/10.1002/chin.199147282.

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39

Venturini, Alessandro, and Javier Gonzalez. "Mechanistic Aspects of the Ketene-Imine Cycloaddition Reactions." Mini-Reviews in Organic Chemistry 3, no. 3 (2006): 185–94. http://dx.doi.org/10.2174/1570193x10603030185.

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40

Fu, Xiaoyuan, Yan Wang, and Decai Fang. "Ab initio studies on the mechanism of dimerization reactions of ketene imine and bis(trifluoromethyl)ketene imine." Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta) 102, no. 1-6 (1999): 87–91. http://dx.doi.org/10.1007/s002140050476.

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41

López, R., D. Suárez, M. F. Ruiz-López, J. González, J. A. Sordo, and T. L. Sordo. "Solvent effects on the stereoselectivity of ketene–imine cycloaddition reactions." J. Chem. Soc., Chem. Commun., no. 16 (1995): 1677–78. http://dx.doi.org/10.1039/c39950001677.

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42

Aitken, R. Alan, Lynn A. Power, and Alexandra M. Z. Slawin. "[3+2] Cycloaddition to a Chiral 5-Methylene-1,3-dioxolan-4-one and Pyrolysis of the Spiro Adducts." Molecules 30, no. 6 (2025): 1246. https://doi.org/10.3390/molecules30061246.

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The [3+2] cycloaddition chemistry of (2S)-5-methylene-2-t-butyl-1,3-dioxolan-4-one, derived from lactic acid, has been examined, and spiro adducts have been obtained with benzonitrile oxide, acetonitrile oxide, diazomethane and diphenyldiazomethane. The structure and absolute stereochemistry of the benzonitrile oxide adduct has been confirmed by X-ray diffraction, and all the adducts have been fully characterised by 1H and 13C NMR. Attempted cycloaddition with a nitrile sulfide, a nitrile imine and azides failed. Pyrolysis results in a range of novel gas-phase reactions, with the nitrile oxide
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43

Lopez, R., T. L. Sordo, J. A. Sordo, and Javier Gonzalez. "Torquoelectronic effect in the control of the stereoselectivity of ketene-imine cycloaddition reactions." Journal of Organic Chemistry 58, no. 25 (1993): 7036–37. http://dx.doi.org/10.1021/jo00077a022.

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44

Jarrahpour, Aliasghar, Mohammad Mahdi Doroodmand, and Edris Ebrahimi. "The first report of [2+2] ketene–imine cycloaddition reactions (Staudinger) on carbon nanotubes." Tetrahedron Letters 53, no. 23 (2012): 2797–801. http://dx.doi.org/10.1016/j.tetlet.2012.03.089.

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45

Downey, C. Wade, Grace Ann L. Robertson, Jhonmattew Santa, Kari R. Flicker, and William M. Stith. "One-pot silyl ketene imine formation-nucleophilic addition reactions of acetonitrile with acetals and nitrones." Tetrahedron Letters 61, no. 9 (2020): 151537. http://dx.doi.org/10.1016/j.tetlet.2019.151537.

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46

Anand, K. Halve, Bhadauria Deepti, Bhaskar Bhuwan, Dubey Rakesh, and Bhadauria Raman. "Design, synthesis and in vitro antibacterial studies of some biologically significant N-3-chloro-4-[2' -hydroxy-5' -(phenylazo)phenyl]azetidin-2-ones." Journal of Indian Chemical Society Vol. 84, Feb 2007 (2007): 193–96. https://doi.org/10.5281/zenodo.5814777.

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School of Studies in Chemistry, Jiwaji University, Gwalior-474 011, Madhya Pradesh, India <em>E-mail</em> : drhalve chemjiwaji@rediffmail.com, dipti_1706@rediffmail.com <em>Manuscript received 28 February 2006, revised 13 September 2006, accepted 29 November 2006</em> The title compounds 3a-h were prepared via the reaction of imine derivatives viz. substituted 2-hydroxy-5-(4&#39;-nitrophenylazo)benzylidine anilines 2a-h with ketenes generated by the reaction of chloroacetylchloride with tridhylamine in 1,4-dioxane. The structures of synthesized compounds were assigned by elemental analysis and
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47

Evans, David A., та J. Michael Williams. "The asymmetric synthesis of β-lactam antibiotics-v. Application of chiral α,β-epoxyimines in ketene-imine cycloaddition reactions leading to homochiral 3-aminoazetidinones." Tetrahedron Letters 29, № 40 (1988): 5065–68. http://dx.doi.org/10.1016/s0040-4039(00)80680-2.

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48

Habib, Osama M., Asaad S. Mohamed, Yehia A. Ibrahim та Nouria A. Al-Awadi. "Sequential Diimination, Staudinger [2 + 2] Ketene–Imine Cycloaddition, and Ring-Closing Metathesis (RCM) Reactions: In Route to Bis(4-spiro-fused-β-lactams)-Based Macrocycles". Journal of Organic Chemistry 86, № 21 (2021): 14777–85. http://dx.doi.org/10.1021/acs.joc.1c01576.

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49

Brandstadter, Stephan M., Iwao Ojima, and Kenji Herai. "Reactions of ketene silyl acetals with imine-complexes of titanium tetrachloride. New and convenient routes to 5,6-dihydro-2-pyridones and 5-amino-2-alkenoates." Tetrahedron Letters 28, no. 6 (1987): 613–16. http://dx.doi.org/10.1016/s0040-4039(00)95794-0.

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50

Xu, Xichen, Yingjun Zhao, Rujie Xu та Zhengqing Xu. "Rh2(esp)2-Catalyzed Redox/Cycloaddition Cascade of Diazoaceto­acetate Enones with N-Methyl Nitrones: Diastereoselective Synthesis of β-Lactams with Two Adjacent Chiral Centers". Synthesis, 1 лютого 2022. http://dx.doi.org/10.1055/s-0040-1719883.

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Abstract:
AbstractA Rh2(esp)2-catalyzed diastereoselective synthesis of highly functionalized β-lactams is developed. By employing Rh2(esp)2 as the catalyst, a reaction cascade operates by reducing an N-methyl nitrone to the corresponding N-methyl imine in the presence of a first molecule of the diazoacetoacetate enone. A second molecule of the diazoacetoacetate enone sensing a change in the reaction medium undergoes a Wolff rearrangement to afford a vinyl ketene. This vinyl ketene then reacts with the in situ generated N-methyl imine to diastereoselectively furnish a β-lactam with two contiguous stereo
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