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Journal articles on the topic 'Ketoacidosis 1'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Jenei, Kinga, Ildikó Szatmári, Eszter Szabó, et al. "Laktátszintváltozások diabeteses ketoacidosisban és frissen diagnosztizált 1-es típusú diabetes mellitusban." Orvosi Hetilap 160, no. 45 (2019): 1784–90. http://dx.doi.org/10.1556/650.2019.31533.

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Abstract: Introduction: It is known that lactate concentration is increased in diabetic ketoacidosis (DKA), however, the pathophysiology and kinetics of lactate changes are still unclear. Normally, L-lactate is the major form in the human body. According to previous data, also D- and L-lactate might be increased in hyperglycaemic disorders. Aim: We aimed to describe the kinetics and mechanisms of lactate concentration changes in ketoacidosis and newly diagnosed diabetes. Method: We performed a prospective study, including 5–18-year-old children with ketoacidosis (DKA, n = 13) and with newly di

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Szypowska, Agnieszka, Anna Ramotowska, Monika Grzechnik-Gryziak, Wojciech Szypowski, Anna Pasierb, and Katarzyna Piechowiak. "High Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes." Journal of Diabetes Research 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/9582793.

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Aim. The aim of this study was to evaluate the incidence of diabetic ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes in 2006-2007 and 2013-2014.Method. The study group consisted of 426 children aged 0–18 years with type 1 diabetes onset admitted to our hospital in 2006-2007 (group A) and 2013-2014 (group B). The study comprised the analysis of medical and laboratory records from patients’ medical charts and the electronic database.Results. There was no difference between groups A and B in the percentage of children admitted with diabetic ketoacidosis (25% versus 2

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Umapathysivam, Mahesh M., Bethany Morgan, Joshua M. Inglis, et al. "SGLT2 Inhibitor–Associated Ketoacidosis vs Type 1 Diabetes–Associated Ketoacidosis." JAMA Network Open 7, no. 3 (2024): e242744. http://dx.doi.org/10.1001/jamanetworkopen.2024.2744.

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This cohort study examines the natural history and response to treatment of sodium glucose cotransporter 2 (SGLT2) inhibitor–associated ketoacidosis compared with that of type 1 diabetes–associated ketoacidosis.

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Tilinca, Mariana Cornelia, Csilla Nania, Sandor Pal, Raluca Tilinca, Monika Szabo, and Eniko Nemes-Nagy. "Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis." Revista de Chimie 71, no. 1 (2020): 239–43. http://dx.doi.org/10.37358/rc.20.1.7839.

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Ketoacidosis is a life-threatening complication of diabetes mellitus, especially type 1 diabetic patients being predisposed to this condition. Ketoacidosis might occur also in other types of diabetes triggered by circumstances leading to shortage of insulin. The aim of the study was the assessment of metabolic, hydroelectrolytic disturbances and the relationship between different parameters in patients hospitalized with diabetic ketoacidosis. We evaluated the clinical state, parameters of blood-gas analyzer, biochemistry and hematology laboratory results of 32 patients admitted with diabetic k

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Gusti, Ayu Sri Ari Swandewi, and Windiyanto Romy. "Recurrent Diabetic Ketoacidosis in Adolescents with Type 1 Diabetes Mellitus." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 04, no. 11 (2024): 881–88. https://doi.org/10.5281/zenodo.14202466.

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<strong>Introduction:</strong> Diabetic ketoacidosis (DKA) is one of the serious complications that is often found in pediatric cases of type 1 diabetes mellitus (DM). Diabetic ketoacidosis mostly occurs in patients with low glycemic control. Currently, many studies are assessing risk factors for recurrent ketoacidosis, including young age, male gender, patients with comorbidities (psychiatric diseases, alcohol or substance abuse, other chronic diseases), and patients with socioeconomic factors. The incidence of recurrent diabetic ketoacidosis in children and adolescents is becoming more

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Kansakar, Prerana, Shrijana Shrestha, Buddhi Prasad Paudyal, Alisha Prajapati, and Narottam Shrestha. "Risk Factors Associated with Diabetic Ketoacidosis at the Onset of Type 1 Diabetes Mellitus." Journal of Nepal Health Research Council 20, no. 01 (2022): 79–83. http://dx.doi.org/10.33314/jnhrc.v20i01.3841.

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Background: There are various factors which increase the risk of diabetic ketoacidosis at the onset of type 1 diabetes mellitus. There have not been any such studies in our setting. This study was done to find the prevalence and risk factors associated with the development of diabetic ketoacidosis at onset of type 1 diabetes mellitus. Methods: Children and young adults with type 1 diabetes mellitus being treated at Patan hospital were approached and after obtaining an informed consent, all the patient information on various risk factors for diabetic ketoacidosis were collected in a pre-develop

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Hassan Khan, Muhammad Imran, Junaid Mushtaq, Ibtesaam Amjad, Israr ul Haque Toor, and Ghias un Nabi Tayyab. "DIABETIC KETOACIDOSIS;." Professional Medical Journal 25, no. 08 (2018): 1235–39. http://dx.doi.org/10.29309/tpmj/2018.25.08.86.

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Objectives: To observe the frequency, precipitating factors and outcome ofdiabetic ketoacidosis (DKA) in adults with established and newly diagnosed type 1 diabetesat a tertiary care hospital. Study Design: Retrospective study. Setting: Lahore GeneralHospital, Lahore. Period: From January 2013 through December 2015. Methods: Patients whowere admitted with a diagnosis of DKA. The clinical presentations, laboratory investigations,management, time of recovery and outcome were compared. Data were collected viaretrospective chart review. Results: A total of 202 patients were included who fulfilled

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Mukha, N. V., A. V. Govirin, А. Р. Filev, N. V. Fetisova, and N. М. Kalashnikova. "PLATELET AGGREGATION FUNCTION IN PATIENTS WITH TYPE 1 DIABETES MELLITUS WITH KETOACIDOSIS OF VARYING DEGREES OF SEVERITY." Transbaikalian Medical Bulletin, no. 1 (May 17, 2024): 66–74. http://dx.doi.org/10.52485/19986173_2024_1_66.

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The aim of the research. To study the aggregation function of platelets in the blood of patients with type 1 diabetes mellitus complicated by ketoacidosis, depending on the severity of ketoacidosis in the dynamics of the disease.Materials and methods. 135 patients with type 1 diabetes mellitus complicated by mild and moderate ketoacidosis were examined, respectively, on the 1st, 5th and 10th days of the disease. The average age of the patients was 29,2±8,9 years. Platelet aggregation was studied using a Biola two-channel laser platelet aggregation analyzer (model LA230, Russia).Results. It was

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Thompson, Brian, and Anthony Kitchen. "Euglycemic Diabetic Ketoacidosis in Type 1 Diabetes on Insulin Pump, with Acute Appendicitis: A Case Report." Clinical Practice and Cases in Emergency Medicine 5, no. 3 (2021): 296–98. http://dx.doi.org/10.5811/cpcem.2021.1.48905.

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Introduction: Recently, euglycemic diabetic ketoacidosis has been an increasing topic of discussion within emergency medicine literature. Euglycemic diabetic ketoacidosis can easily be missed, as a normal point-of-care glucose often mistakenly precludes the work-up of diabetic ketoacidosis. Case Report: A 16-year-old female with a past medical history of type 1 diabetes presented to the emergency department with altered mental status, vomiting, and abdominal pain. She was diagnosed with euglycemic diabetic ketoacidosis. Conclusion: Reported cases of euglycemic diabetic ketoacidosis are most fr

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Park, C. "Diabetic ketoacidosis." Journal of the Royal College of Physicians of Edinburgh 37, no. 1 (2007): 40–43. https://doi.org/10.1177/1478271520073701012.

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Diabetic ketoacidosis remains the most important acute complication of diabetes mellitus, causing metabolic decompensation with an associated morbidity and mortality of 1–10%. Although levels of morbidity and mortality are falling with modern management protocols, a significant threat still remains. While DKA is most common in patients with type 1 diabetes mellitus, it should not be overlooked in patients with type 2 diabetes mellitus, especially in those who require insulin. In contrast to chronic management, acute complications often present to Acute Medicine rather than to specialist diabet

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Valenzuela-Vallejo, Laura, Sofía A. López-Ramírez, Verónica Morales-Burton, Sara Aguilera-Martínez, Martha I. Álvarez-Olmos, and Paola Durán-Ventura. "Pediatric diabetic ketoacidosis as type 1 diabetes debut with concurrent SARS-CoV-2 infection: A case report." SAGE Open Medical Case Reports 10 (January 2022): 2050313X2210972. http://dx.doi.org/10.1177/2050313x221097263.

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Diabetic ketoacidosis is a life-threatening complication associated with type 1 diabetes (T1D). Recent evidence suggests that SARS-CoV-2 could trigger diabetic ketoacidosis in type 1 diabetes susceptibility and previous insulitis; however, the data on SARS-CoV-2-infected patients with diabetic ketoacidosis as their type 1 diabetes are still limited. We report a 13-year-old Latinamerican male with symptoms and laboratory tests diagnostic of diabetic ketoacidosis and positive SARS-CoV-2 reverse transcription polymerase chain reaction, who required mild COVID-19 care management, fluid resuscitati

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Samardzic, Mira, Natasa Terzic, and Milena Popovic. "Diabetic ketoacidosis in children with newly detected type 1 diabetes in Montenegro from 1999 to 2008." Medical review 65, no. 11-12 (2012): 503–6. http://dx.doi.org/10.2298/mpns1212503s.

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Introduction. The aim of the study was to analyze the prevalence of diabetic ketoacidosis during the period of 10 years (1999-2008) among children diagnosed with type 1 diabetes in Montenegro. Material and Methods. A retrospective population-based incidence study was performed. The study participants were selected from two independent sources: the diabetes register and hospital records. The following parameters were measured before the first insulin injection: plasma glucose, blood gas analysis, electrolytes, creatinine, insulin, c-peptide, and HbA1c. Diabetic ketoacidosis was defined as pH &l

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Laine, Christine. "Diabetic Ketoacidosis." Annals of Internal Medicine 152, no. 1 (2010): ITC1. http://dx.doi.org/10.7326/0003-4819-152-1-201001050-01001.

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Crenshaw, Kathy L., and Mark E. Peterson. "Pretreatment clinical and laboratory evaluation of cats with diabetes mellitus: 104 cases (1992–1994)." Journal of the American Veterinary Medical Association 209, no. 5 (1996): 943–49. http://dx.doi.org/10.2460/javma.1996.209.05.943.

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Objective To assess pretreatment clinical and laboratory findings in cats with diabetes mellitus and to determine the influence of ketoacidosis on pretreatment findings. Design Retrospective case series. Animals 104 cats with diabetes melliitus, 38 of which had ketoacidosis. Procedure Medical records of cats with diabetes mellitus examined over a 20-month period were reviewed. Cats that had received previous treatment for diabetes mellitus, or for which medical records were incomplete, were excluded from this study. Results Cats ranged in age from 1 to 19 years (median, 11 years). Male cats we

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Hoff, Ryan, and Chung-Kay Koh. "Isoproterenol Induced Insulin Resistance Leading to Diabetic Ketoacidosis in Type 1 Diabetes Mellitus." Case Reports in Endocrinology 2018 (December 17, 2018): 1–3. http://dx.doi.org/10.1155/2018/4328954.

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Isoproterenol is known to cause insulin resistance and is often used to treat bradyarrhythmias from atrioventricular block. We report a case of isoproterenol induced diabetic ketoacidosis in a 77-year-old female patient treated with isoproterenol for atrioventricular block prior to insertion of permanent pacemaker. Diabetic ketoacidosis (DKA) developed within hours of starting an isoproterenol drip, and there were no other precipitating factors at that time. DKA resolved quickly after discontinuing isoproterenol and starting insulin drip. DKA is a common complication of diabetes mellitus, with

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McAllister, Victoria. "Diabetic ketoacidosis." InnovAiT: Education and inspiration for general practice 10, no. 12 (2017): 721–27. http://dx.doi.org/10.1177/1755738017735779.

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Diabetic ketoacidosis is a potentially life-threatening condition that affects people with diabetes mellitus. It typically affects people with type 1 diabetes and can be a first presentation for people not yet diagnosed. It can also affect people with type 2 diabetes, although this is much more uncommon. This article aims to increase understanding of a condition where prompt recognition and rapid management by GPs is essential in preventing morbidity and mortality.

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Kartawinata, Muhammad Ikhsan, and Yusni Puspita. "A Case Report : Diabetic Ketoacidosis in patient with type 1 Diabetes Mellitus with Complication Septic Shock and AKI Stage III on HD Triggered by Perianal Abscess." Journal of Anesthesiology and Clinical Research 1, no. 1 (2020): 26–30. http://dx.doi.org/10.37275/jacr.v1i1.194.

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ABSTRACT Introduction. Diabetic ketoacidosis (DKA) is an acute, life-threatening complication in diabetes mellitus. Infection is a common precipitating cause of diabetic ketoacidosis (DKA) in known diabetic patient, and diabetic ketoacidosis (DKA) often presents as the first symptom of an undiagnosed diabetes. diabetic ketoacidosis (DKA) is diagnosed with combination of hyperglicaemia, acidosis metabolic and ketonuria. Case Presentation. A 27 years old male patient, admitted to Intensive Care Unit with decrease level of consciousness (GCS 3), he was intubated and present with respi

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Kartawinata, Muhammad Ikhsan, and Yusni Puspita. "A Case Report: Diabetic Ketoacidosis in Patient with type 1 Diabetes Mellitus with Complication Septic Shock and AKI Stage III on HD Triggered by Perianal Abscess." Journal of Anesthesiology and Clinical Research 1, no. 1 (2021): 26–30. http://dx.doi.org/10.37275/jacr.v1i1.135.

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Introduction. Diabetic ketoacidosis (DKA) is an acute, life-threatening complication in diabetes mellitus. Infection is a common precipitating cause of diabetic ketoacidosis (DKA) in known diabetic patient, and diabetic ketoacidosis (DKA) often presents as the first symptom of an undiagnosed diabetes. diabetic ketoacidosis (DKA) is diagnosed with combination of hyperglicaemia, acidosis metabolic and ketonuria. Case Presentation. A 27 years old male patient, admitted to Intensive Care Unit with decrease level of consciousness (GCS 3), he was intubated and present with respiratory distress

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Foti Randazzese, Simone, Mariarosaria La Rocca, Bruno Bombaci, et al. "Severe Diabetic Ketoacidosis in Children with Type 1 Diabetes: Ongoing Challenges in Care." Children 12, no. 1 (2025): 110. https://doi.org/10.3390/children12010110.

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Diabetic ketoacidosis is the most common acute complication in children and adolescents with type 1 diabetes, and contributes significantly to morbidity, mortality, and healthcare burden. This review aims to explore the multifaceted aspects of severe diabetic ketoacidosis in pediatric age, including its epidemiology, pathogenesis, risk factors, complications and emphasizing advances in prevention strategies. Incidence rates vary due to influences from geographic, socioeconomic, cultural and demographic factors. Pathogenesis is linked to insulin deficiency and an excess of counter-regulatory ho

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Albuali, Waleed H., Abdullah A. Yousef, Mohammad H. Al-Qahtani, et al. "A Clinical and Biochemical Comparative Study Of Diabetic Ketoacidosis (DKA) in Newly Diagnosed Vs Known Cases of Type 1 Diabetic Children." Review of Diabetic Studies 19, no. 1 (2023): 28–33. http://dx.doi.org/10.1900/rds.2023.19.28.

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Objectives: We aimed to study the characterizing clinical and biochemical profiles of Diabetic Ketoacidosis (DKA) in children with newly diagnosed Type 1 Diabetes Mellitus (Type 1DM) compared to children with established diagnosis of Type 1DM presenting with DKA admitted to the pediatric intensive care unit of a large university hospital in the eastern region of Saudi Arabia. Methods: We retrospectively reviewed the medical records of 211 patients who were admitted to the pediatric intensive care unit with diabetic ketoacidosis between 2010 and 2019. The diagnosis of diabetic ketoacidosis was

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Khan, Muhammad Imran Hassan, Junaid Mushtaq, Ibtesaam Amjad, Israr ul Haque Toor, and Ghias un Nabi Tayyab. "DIABETIC KETOACIDOSIS." Professional Medical Journal 25, no. 08 (2018): 1235–39. http://dx.doi.org/10.29309/tpmj/18.4744.

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Nurhakim, Lukman, Rudy Afriant, and Dinda Aprilia. "Diabetic Ketoacidosis in Type 1 Diabetes Mellitus." Sumatera Medical Journal 7, no. 1 (2024): 51–54. http://dx.doi.org/10.32734/sumej.v7i1.11837.

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Introduction: Diabetic ketoacidosis (DKA) is a state of metabolic decompensation/disorder characterized by the triad of hyperglycemia, acidosis and ketosis, caused by absolute or relative insulin deficiency and increased counter-regulatory hormones. Immediate therapy in DKA patients determines the patient's prognosis Case Report: A 19-year-old male treated in the internal medicine ward of Dr. M djamil Padang with diabetic ketoacidosis, type 1 DM, and Abscess capitis. The patient was treated with rehydration and intravenous insulin infusion can show clinical improvement. Conclusion: The diagnos

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di Mauro, Gabriella, Annamaria Mascolo, Mario Gaio, et al. "The Reporting Frequency of Ketoacidosis Events with Dapagliflozin from the European Spontaneous Reporting System: The DAPA-KETO Study." Pharmaceuticals 15, no. 3 (2022): 286. http://dx.doi.org/10.3390/ph15030286.

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Dapagliflozin was associated with an increased risk of diabetic ketoacidosis that has led to the European withdrawal of the authorization for the type 1 diabetes. However, it is still used for the treatment of type 2 diabetes. Therefore, we aim to evaluate the occurrence of dapagliflozin-induced ketoacidosis events by using the European spontaneous reporting system. The reporting odds ratios (ROR) were computed to assess the reporting frequency of ketoacidosis events for dapagliflozin compared to Dipeptidyl peptidase-4 (DPP-4) inhibitors, insulins, or all other Sodium-glucose cotransporter-2 (

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Gavidia Quezada, Rocio, and Hawa Edriss. "Diabetic ketoacidosis: Should current management include subcutaneous insulin injections?" Southwest Respiratory and Critical Care Chronicles 5, no. 19 (2017): 6. http://dx.doi.org/10.12746/swrccc.v5i19.389.

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Diabetic ketoacidosis is a well-known acute complication in patients with both type 1 andtype 2 diabetes mellitus. Although mortality has decreased considerably, it remains an importantcause for admission to intensive care units. Medical management includes intravenous fluidtherapy, insulin, correction of electrolyte abnormalities, and addressing the precipitating factorwhich in most cases is infection or non-compliance with insulin therapy. Usually patients withdiabetic ketoacidosis are admitted to the intensive care unit for continuous infusion of insulin;however, the development of rapid ac

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Williamson, Scott, Vicky Alexander, and Stephen Alan Greene. "Severe hyperlipidaemia complicating diabetic ketoacidosis: Figure 1." Archives of Disease in Childhood 97, no. 8 (2012): 735. http://dx.doi.org/10.1136/archdischild-2012-301810.

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Fernández-García, José C., Juan P. Arrebola, Stella González-Romero, Federico Soriguer, Nicolás Olea, and Francisco J. Tinahones. "Diabetic ketoacidosis following chlorothalonil poisoning: Table 1." Occupational and Environmental Medicine 71, no. 5 (2014): 382. http://dx.doi.org/10.1136/oemed-2013-101795.

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Ahmed, Asma, Kaleemullah Badini, Farah Khalid, Sahlah Sohail, and Muhammad Salik. "Comparison of ketoacidosis in type 1 and 2 diabetic patients with and without concurrent COVID-19 and determining the factors affecting their treatment and survival: a retrospective cohort study." Journal of the Pakistan Medical Association 74, no. 12 (2024): 2072–77. http://dx.doi.org/10.47391/jpma.9651.

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Objective: To assess the incidence of diabetic ketoacidosis in coronavirus disease-2019 patients and their survival rate, and to compare their outcomes with diabetic ketoacidosis patients without coronavirus disease-2019. Method: The retrospective cohort study was conducted at Aga Khan University Hospital, Karachi, and comprised data March 1, 2020, to March 31, 2021, related to patients. who had diabetic ketoacidosis with coronavirus disease-2019 in group A, and those who had diabetic ketoacidosis without coronavirus disease-2019 in group B. Data included age, gender, duration and type of diab

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Nabavi, Seyed Salaheddin, Fahimeh Soheilipour, Motahare Aghajani Delavar, et al. "The investigation of the relationship between vitamin D level and severity of diabetic ketoacidosis in new cases of type 1 diabetes in children referred to Hazrat-E- Ali-Asghar Hospital in 2021." Journal of Family Medicine and Primary Care 13, no. 11 (2024): 4943–48. http://dx.doi.org/10.4103/jfmpc.jfmpc_375_24.

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ABSTRACT Background and Purpose: According to the role of 25-hydroxyvitamin D (25OHD) in glucose homeostasis and immune modulation, vitamin D deficiency may be associated with type 1 diabetes and diabetic ketoacidosis (DKA). Therefore, this study was conducted with the aim of investigation of the relationship between the vitamin D level and severity of diabetic ketoacidosis in new cases of type 1 diabetes in children referred to Hazrat-E-Ali-Asghar Hospital in 2021. Methods: The present study is based on a cross-sectional study. The population studied in this research includes new cases of chi

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Botelho, Teresa A., Joana M. N. Santos, Crisbety M. S. Pinho, et al. "Ketoacidosis in new-onset type 1 diabetes: did the severity increase during the COVID-19 pandemic?" Journal of Pediatric Endocrinology and Metabolism 35, no. 1 (2021): 73–77. http://dx.doi.org/10.1515/jpem-2021-0449.

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Abstract Objectives Since the beginning of the COVID-19 pandemic, there has been a consistent decrease in the number of admissions to the emergency department, leading to a delay in the diagnosis of several pathologies. The time from onset of symptoms to the diagnosis of Type 1 diabetes is highly variable. This treatment delay can lead to the appearance of ketoacidosis. Methods Retrospective study of inaugural Type 1 diabetes cases, from March 2016 to March 2021. The pandemic group was considered between March 2020 to March 2021, and the remaining period was considered as pre-pandemic. Clinica

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Kuntjoro, Astrellatiffany, and Arnold Soetarso. "Diabetic Ketoacidosis in Children." Cermin Dunia Kedokteran 51, no. 11 (2024): 644–47. http://dx.doi.org/10.55175/cdk.v51i11.1083.

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The incidence of diabetic ketoacidosis (DKA) in children with type 1 diabetes mellitus reaches 1–12 per 100 patients each year. The case is a boy aged 13 years 10 months with chief complaints of weakness and drowsiness. Blood sugar levels 532 mg/dL, blood ketone levels 6.6, blood pH 7.13, HbA1c 19.2%. The principles of DKA management include fluid therapy, insulin, electrolyte balance, treat the underlying disease, and monitor complications.

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TUCKER, MIRIAM E. "Diabetic Ketoacidosis Costs Up." Clinical Endocrinology News 2, no. 11 (2007): 11. http://dx.doi.org/10.1016/s1558-0164(07)70580-1.

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Singh, Sandip Kumar, Shikha Rijal, Vijay Kumar Sah, Babita Khanal, and Arun Giri. "Analysis of Prolonged Pediatric Intensive Care Stay in Children with Diabetic Ketoacidosis." Journal of Nobel Medical College 9, no. 1 (2020): 46–50. http://dx.doi.org/10.3126/jonmc.v9i1.29530.

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Background: Diabetic ketoacidosis is one of most serious complication of diabetes requiring intensive care management. We aim to analyze various factors responsible for prolonged duration of stay in pediatric intensive care unit in a child with Diabetic Ketoacidosis. Materials and Methods: This was a hospital based prospective observational study conducted in Nobel Medical College and Teaching Hospital among children with Diabetic ketoacidosis over the period of one year. A total of 22 cases with Diabetic ketoacidosis aged 1 month to 18 years were included and clinical profile, laborator

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Kavin, Kumar, Maheshwari Sanjiv, Yadav Yadram, Devgan Yash, Sankol Anil, and Gupta Gaurav. "To Assess the Correlation of Serum Phosphorus Level in Diabetic Ketoacidosis in Type-2 Diabetes Mellitus." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 1029–31. https://doi.org/10.5281/zenodo.11224355.

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Background: In DKA patients, phosphate and magnesium level are decreased and further reduction may occur during insulin treatment. But, usually, these electrolytes are not given, when the patient takes oral diet. If the phosphate level is low, and the patient is not taking oral diet, potassium phosphate can be given. If magnesium level found low level in DKA patient, who developed cardiac arrhythmias, magnesium sulfate can be given. Otherwise, routine supplementation is not needed. Methods: Phosphorus levels was estimated on 1 day, 3 day and discharge/worsening of patient. It was correlated to

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Luo, Jingmei, Jiagang Feng, Chunyan Liu, et al. "Type 1 diabetes mellitus induced by PD-1 inhibitors in China: a report of two cases." Journal of International Medical Research 50, no. 9 (2022): 030006052211219. http://dx.doi.org/10.1177/03000605221121940.

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The immune-related adverse events associated with immunotherapy may affect endocrine glands and other tissues. Two Chinese patients with malignancies were treated with programmed cell death-1 (PD-1) inhibitors (nivolumab and pembrolizumab) and followed up with biochemical tests over 1 year. After PD-1 treatment for 6 to 10 months, the patients developed symptoms of diabetes, ketoacidosis, and insulin secretion failure. Type 1 diabetes mellitus was confirmed by the characteristic fluctuation of blood glucose that was controlled with multiple daily insulin injections. Neither patient’s insulin d

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Paudel, Ujjawal, Buddhi Prasad Paudyal, Prerana Kansakar, and Mila Shakya. "Clinical characteristics and perspectives of children and youths with type 1 diabetes attending Patan Hospital, Nepal." Journal of Patan Academy of Health Sciences 8, no. 1 (2021): 113–20. http://dx.doi.org/10.3126/jpahs.v8i1.36865.

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Introduction: Type 1 Diabetes Mellitus (DM1) has reportedly a high proportion of initial presentation as diabetic ketoacidosis, more in resource-poor settings. This study was designed to assess the demographics and clinical characteristics of DM1 patients as well as their perception of diabetes management in local scenario.  Method: This is a cross-sectional study of data collected prospectively by a questionnaire survey among young patients with DM1 presenting to Medical and Paediatric Referral Clinics of Patan Hospital, Nepal during April 2016 to June 2016. Ethical approval was obtaine

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Tavares Oliveira Ramos, Thaynara, Juliana Andreia Fernandes Noronha, Brenda Sales Lins, Maria Cecília Queiroga dos Santos, Sheila Milena Pessoa dos Santos, and Anajás da Silva Cardoso Cantalice. "DIABETIC KETOACIDOSIS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS AND ASSOCIATED RISK FACTORS." Cogitare Enfermagem, no. 27 (September 28, 2022): 1–12. http://dx.doi.org/10.5380/ce.v27i0.87274.

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Objective: to estimate the prevalence and risk factors of diabetic ketoacidosis in children and adolescents with Type 1 Diabetes Mellitus.Method: an epidemiological, cross-sectional and cohort study that analyzed the medical charts of children and adolescents with Type 1 Diabetes Mellitus admitted over a 10-year period to a public reference hospital in the municipality of Campina Grande, Brazil, from 2009 to 2019. The data were analyzed by means of descriptive statistics, both bivariate and multivariate through Poisson regression.Results: 130 medical charts were analyzed, of which 46.2% presen

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Charoensri, Suranut, Jin Sothornwit, Akeatit Trirattanapikul, and Chatlert Pongchaiyakul. "Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes." Case Reports in Endocrinology 2021 (February 8, 2021): 1–4. http://dx.doi.org/10.1155/2021/6620832.

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Ketogenic diet, a very low-carbohydrate diet and high-fat diet, has emerged as a popular approach for weight reduction, particularly in young adults. However, a serious but rare complication of the ketogenic diet is ketoacidosis associated with low carbohydrate intake, which should be cautiously monitored in people with a predisposition to the condition. We report a 22-year-old Thai woman with an unremarkable past medical history who presented with an acute onset of dyspnea of 2 days’ duration. Diabetic ketoacidosis was diagnosed by elevated capillary blood glucose, significant metabolic acido

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John, Robert, Hemang Yadav, and Martin John. "Euglycemic ketoacidosis as a cause of a metabolic acidosis in the Intensive Care Unit." Acute Medicine Journal 11, no. 4 (2012): 219–21. http://dx.doi.org/10.52964/amja.0578.

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Euglycaemic ketoacidosis is a rare endocrine emergency, which can have disastrous consequences if left undiagnosed. We present the case of a 57 year old man with type 2 diabetes who developed ketoacidosis (DKA) following a myocardial infarction, despite being normoglycaemic, following discontinuation of his insulin infusion in an intensive care setting. The case highlights the importance of capillary ketone body testing in this scenario as well as the dangers of an over reliance on blood glucose values in the diagnosis of ketoacidosis. The notion that DKA can occur in both type 1 and type 2 di

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Masand, Prakash S. "New-Onset diabetes and ketoacidosis." Current Psychiatry Reports 2, no. 3 (2000): 232–33. http://dx.doi.org/10.1007/s11920-996-0015-1.

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Kotwal, Suman Kumar, Som Nath Verma, and Annil Mahajan. "Thyrotoxicosis Precipitating Diabetic Ketoacidosis: A case report." Indian Journal of Medical and Health Sciences 5, no. 2 (2018): 80–82. http://dx.doi.org/10.21088/ijmhs.2347.9981.5218.5.

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Background: Diabetic ketoacidosis (DKA) is acute complication of diabetes mellitus. It is commonly seen in type 1 diabetes mellitus and rarely also seen in type 2 diabetes mellitus. In more than fifty percent of cases precipitating factor is usually unrecognized. Case report: A 35 years women with type 1 diabetes mellitus presented with (DKA), with no apparent precipitating factor. Following initial correction of the DKA, persisting tachycardia, thyromegaly and thyroid functions confirmed diagnosis of thyrotoxicosis. Treatment with propranolol and carbimazole helped in the normalization of met

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Miolski, Jelena, Maja Ješić, Smiljka Kovačević, Jelena Blagojević, and Vera Zdravković. "Diabetic ketoacidosis: Our experiences." Medicinski casopis 55, no. 2 (2021): 71–74. http://dx.doi.org/10.5937/mckg55-31440.

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Diabetic ketoacidosis is an acute complication in children with type 1 diabetes mellitus. It is diagnosed if the sugar value is > 11 mmol / l, pH <7.3, HCO3≤ 15 mmol / l, with ketonemia or ketonuria. Based on serum pH and bicarbonate values it could be mild, moderate, and severe. It is manifested by rapid breathing, abdominal pain, nausea, vomiting, altered state of consciousness. Early recognition of symptoms prevents the possibility of serious complications. Treatment includes fluid replacement, rehydration, insulin therapy, electrolyte replacement, glucose correction. This paper prese

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Gaikwad, Vijaykumar, J. K. Deshmukh, Prachi Deshmukh, and Anant A. Takalkar. "Clinical features and risk factors for diabetic ketoacidosis in type 1 diabetes mellitus at tertiary care centre, Maharashtra, India." International Journal of Advances in Medicine 7, no. 5 (2020): 745. http://dx.doi.org/10.18203/2349-3933.ijam20201609.

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Background: Diabetes Mellitus is increasing in incidence, prevalence and importance as a chronic disease throughout the world. The International Diabetes Federation projects that by 2030 there will be 438 million people with diabetes on a global scale. Three essential components of Diabetic Ketoacidosis are hyperglycemia, ketosis, and resultant metabolic acidosis. 4% of all patients with diabetes and 20% of those with Type 1 Diabetes are admitted to hospital with manifestations of ketoacidosis. Objectives was to study clinical profile of patients presenting as Diabetic Ketoacidosis.Methods: It

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Dashora, Umesh, Dipesh C. Patel, Robert Gregory, Peter Winocour, Ketan Dhatariya, and Dinesh Nagi. "Association of British Clinical Diabetologists (ABCD) position statement on the use of sodium-glucose cotransporter-2 inhibitors in type 1 diabetes (updated 2019)." British Journal of Diabetes 19, no. 1 (2019): 66–72. http://dx.doi.org/10.15277//bjd.2019.208.

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SGLT-2 inhibitors may be increasingly used in people with type 1 diabetes as new licenses are obtained. These drugs have the potential to improve glycaemic control in people with type 1 diabetes with the added benefit of weight loss, better control of blood pressure and more time in optimal glucose range. SGLT-2 inhibitors are associated with higher incidence of diabetic ketoacidosis without significant hyperglycaemia. The present ABCD position statement is to mitigate this risk and other potential complications in people taking these drugs. Particular caution needs to be exercised in people w

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Jali, Mallikarjun V., Vishwanath D. Patil, Sujata M. Jali, Shivaraj Gowda, and Sanjay Kambar. "Type 1 diabetes mellitus with ketoacidosis in infancy." Indian Journal of Pediatrics 76, no. 4 (2009): 424–26. http://dx.doi.org/10.1007/s12098-009-0009-1.

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Karki, Lochan, Milan Khadka, Milan Purna Oli, et al. "Diabetic Ketoacidosis among Diabetic Patients Admitted in the Department of Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study." Journal of Nepal Medical Association 61, no. 261 (2023): 409–12. http://dx.doi.org/10.31729/jnma.8158.

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Introduction: Diabetic ketoacidosis is one of the most severe acute complications of diabetes mellitus characterised by hyperglycemia, hyperketonemia, and metabolic acidosis. Prompt diagnosis and treatment of diabetic ketoacidosis can decrease severity, hospital stay, and possible mortality. This study aimed to find out the prevalence of diabetic ketoacidosis among diabetic patients admitted to the department of medicine of a tertiary care centre. Methods: This descriptive cross-sectional study was conducted at a tertiary care centre. Data from 1 March 2022 to 1 December 2022 were collected be

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Ababulgu, Roza Zinab, and Behailu Terefe Tesfaye. "Characteristics and Outcomes of Children with Type-I Diabetes Mellitus Hospitalized for Ketoacidosis." Current Diabetes Reviews 16, no. 7 (2020): 779–86. http://dx.doi.org/10.2174/1573399815666190906152125.

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Background: Type 1 diabetes mellitus is a common autoimmune disorder that often presents in children. In these patients, diabetic ketoacidosis is one of the most common and serious acute complications associated with significant morbidity and mortality. Nevertheless, limited studies are conducted in Ethiopia. Objective: The aim of this study was to assess patient-related characteristics and outcomes of diabetic ketoacidosis, and their relative difference among children with newly diagnosed and previously known type-I diabetes mellitus. Methods: This is a retrospective cross-sectional study of

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Al-Qahtani, Mohammad Hussain, Aqilah Taleb Al-Qassab, Fatimah Mousa Bukhamseen, et al. "Severity and Resolution of Diabetic Ketoacidosis in Newly Diagnosed Type 1 Diabetic Children before and During The COVID-19 Pandemic." Review of Diabetic Studies 18, no. 4 (2022): 181–86. http://dx.doi.org/10.1900/rds.2022.18.181.

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OBJECTIVES: To epidemiologically assess the influence of COVID-19 pandemic on newly diagnosed type 1 diabetes mellitus presenting with diabetic ketoacidosis at the teaching hospital of the university, Eastern province, Saudi Arabia. METHODS: We enrolled newly diagnosed type 1 diabetes mellitus cases among pediatric patients attending the emergency department and outpatient clinics during 2019-2021. The participants' data were collected from electronic medical records which included patients' age at diagnosis, sex, nationality, height, weight, year of diagnosis, length of stay, presentation, ra

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Coutada, Rosália S., Soraia S. Cunha, Elisabete S. Gonçalves, Ana P. Gama, João P. Silva, and Paula M. Pinheiro. "Diabetic ketoacidosis in pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 7 (2018): 2945. http://dx.doi.org/10.18203/2320-1770.ijrcog20182912.

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Diabetic ketoacidosis in pregnancy is a rare but potential life-threatening condition for the mother and the fetus. It tends to occur latter in pregnancy and is more common in patients with pregestational diabetes. Obstetricians should be aware of the events that can trigger diabetic ketoacidosis in pregnancy. Prompt recognition and aggressive treatment of this condition are essential in order to reduce perinatal mortality and morbidity. The authors present a case of a pregnant woman with type 1 diabetes with a poor surveillance of pregnancy and noncompliance to treatment that develops severe

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Alkhalifah, Yasir. "Boerhaave syndrome in a paediatric patient with diabetic ketoacidosis: A case report." Scripta Medica 55, no. 6 (2024): 803–9. https://doi.org/10.5937/scriptamed55-53998.

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Diabetic ketoacidosis is a serious and potentially life-threatening complication of type 1 diabetes mellitus (T1DM), which often results from poor glycaemic control. While diabetic ketoacidosis is well documented, rare complications such as Boerhaave syndrome can considerably increase morbidity. This case report presents a 14-year-old girl with poorly controlled T1DM and celiac disease who was admitted with diabetic ketoacidosis and developed severe vomiting and abdominal pain. Imaging studies revealed the presence of pneumomediastinum, which raised concerns about oesophageal injury and a diag

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J.R. EKOUNDZOLA, H. BOUALAM, F. ETTALIBI, S. RAFI, G. EL MGHARI, and N. EL ANSARI. "Pneumomediastinum in Diabetic Ketoacidosis: A case report." World Journal of Advanced Research and Reviews 17, no. 3 (2023): 968–70. http://dx.doi.org/10.30574/wjarr.2023.17.3.0495.

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Pneumomediastinum (PM) is the presence of air within the mediastinum. It is a rare illness that affects 1 in 33,000 people in the general population, according to reports. It is a rare complication of diabetic ketoacidosis (DKA). We report a case of pneumomediastinum complicating an inaugural diabetic ketoacidosis.

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