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Journal articles on the topic 'Ketorolaco'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Palo Núñez, Gloria Pamella, and Jesús Orlando Jiménez Castro. "Ketorolaco versus Metamizol en el tratamiento del dolor posoperatorio en niños." Horizonte Médico (Lima) 15, no. 4 (2014): 27–32. http://dx.doi.org/10.24265/horizmed.2015.v15n4.05.

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Barroso Casamitjana, E., B. Isla Tejera, J. Ruano Ruiz, and A. Blanco-Molina. "Vasculitis cutánea por hipersensibilidad probablemente causada por ketorolaco trometamol." Farmacia Hospitalaria 30, no. 1 (2006): 60–61. http://dx.doi.org/10.1016/s1130-6343(06)73946-0.

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Llambo-Villacrés, E. H., D. R. Villamarín-Barragan, D. F. Avilés-Esquivel, and E. L. Valle-Velástegui. "Efecto analgésico intraoperatorio de ketorolaco, meloxicam y ketoprofeno por goteo continuo en cirugías de oforosalpingohisterectomía (OSH) en caninos." Revista Ecuatoriana de Investigaciones Agropecuaria 2, no. 1 (2018): 8. http://dx.doi.org/10.31164/reiagro.v2n1.2.

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El presente estudio evaluó el control del dolor intraoperatorio en 54 caninos hembras mediante AINEs administrados por vía intravenosa a goteo continuo en cirugías de oforosalpingohisterectomía; se dividieron aleatoriamente en 9 grupos de 6 individuos, las dosis utilizadas fueron: ketoprofeno (F1) 0.5 mg/kg, 1 mg/kg, 1.5 mg/kg; meloxicam (F2) 0.025 mg/kg, 0.05 mg/kg, 0.1 mg/kg y ketorolaco (F3) 0.12 mg/kg, 0.2 mg/kg, 0.5 mg/kg. Se midió: Frecuencia Cardiaca, Frecuencia Respiratoria, Saturación de oxígeno, Presión Arterial Media y Temperatura. La analgesia post operatoria se evaluó mediante la

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Cano Vargas-Machuca, Enrique, Beatriz Mondéjar Marín, Santiago Navarro Muñoz, Inmaculada Pérez Molina, José Antonio Garrido Robres, and Araceli Álvarez Tejerina. "Meningitis recurrente aséptica secundaria a toma de ibuprofeno y ketorolaco." Revista de Neurología 42, no. 04 (2006): 217. http://dx.doi.org/10.33588/rn.4204.2005549.

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Ángeles González-Fernández, M. "Adecuación del uso de ketorolaco en un hospital de traumatología." Revista de Calidad Asistencial 24, no. 3 (2009): 115–23. http://dx.doi.org/10.1016/s1134-282x(09)71140-6.

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Córdova-González, Irais, and Jessica Román-Romero. "Analgesia preventiva versus analgesia postoperatoria con paracetamol + ketorolaco en colecistectomía laparoscópica." Revista Mexicana de Anestesiología 44, no. 1 (2021): 8–12. http://dx.doi.org/10.35366/97772.

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Graos Salazar, Karin Maria, and Miguel Perea Paz. "Medicación analgésica postquirúrgica en pacientes atendidos en el Servicio de Odontología Pediátrica de la Clínica Estomatológica Central Cayetano Heredia (2000-2004)." Revista Estomatológica Herediana 17, no. 2 (2014): 53. http://dx.doi.org/10.20453/reh.v17i2.1858.

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El presente estudio tuvo como propósito determinar la frecuencia en el uso de medicamentos analgésicos posquirúrgicos prescritos en pacientes atendidos en un Servicio de Odontología Pediátrica. El grupo estuvo constituido por 91 historias clínicas de pacientes pediátricos sometidosa intervenciones quirúrgicas menores en el periodo del 2000 al 2004. La distribución de la muestra según sexo fue: 37,4% mujeres y 62,6% varones siendo el promedio de edad 8,82+2,43 años. En el análisis de los resultados se utilizo la distribución de frecuencia para determinar lostipos de cirugía, tipo y número de fá

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Castro-Pastrana, L. I., M. Cerro-López, M. L. Toledo-Wall, L. M. Gómez-Oliván, and M. D. Saldívar-Santiago. "Análisis de fármacos en aguas residuales de tres hospitales de la ciudad de Puebla, México." Ingeniería del agua 25, no. 1 (2021): 59. http://dx.doi.org/10.4995/ia.2021.13660.

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<p>Mediante sus efluentes, los hospitales contribuyen a la ocurrencia de microcontaminantes emergentes como los fármacos, en el agua. Este trabajo cuantificó la presencia de nueve fármacos en las aguas residuales de tres hospitales privados de México con 66, 92 y 120 camas, respectivamente. Las muestras se caracterizaron fisicoquímicamente y, empleando cromatografía líquida de alta resolución acoplada a espectrometría de masas (UPLC-MS/MS), se reportaron las siguientes concentraciones máximas promedio: paracetamol (38740.11±33832.15 ng/L), naproxeno (6321.42±11074.86 ng/L), ketorolaco (1

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Cabrera, J., M. Mancuso, F. Cabrera-Fránquiz, J. Limiñana, and A. Díez. "Estabilidad y compatibilidad de la mezcla de tramadol, ketorolaco, metoclopramida y ranitidina en una solución para perfusión intravenosa." Farmacia Hospitalaria 35, no. 2 (2011): 80–83. http://dx.doi.org/10.1016/j.farma.2010.01.007.

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Calle, Ana, Liliana Guevara-Saldaña, and Ricardo Cardona. "Anafilaxia por clorhexidina en un contexto perioperatorio: diagnóstico y manejo." Revista Alergia México 65, no. 4 (2018): 431. http://dx.doi.org/10.29262/ram.v65i4.347.

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Antecedentes: Durante una cirugía, el paciente está expuesto a múltiples medicamentos y moléculas que pueden asociarse con el desarrollo de hipersensibilidad, lo que dificulta la detección del agente causal de la reacción perioperatoria y hace necesaria la realización de pruebas guiadas por alergología.Reporte de caso: Hombre de 53 años quien posterior a una artroscopia de rodilla derecha se le administró ketorolaco endovenoso; a los 12 minutos se inició brote cutáneo pruriginoso en tórax, abdomen y extremidades; de inmediato se suspendió la infusión del medicamento y se administraron 100 mg d

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NASIR, MUHAMMAD, KHAWAR LATIF, and MALIK JAMIL AHMAD. "PRE-EMPTIVE PAIN CONTROL." Professional Medical Journal 14, no. 04 (2007): 591–97. http://dx.doi.org/10.29309/tpmj/2007.14.04.4812.

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Introduction: Opioid related side effects have encouraged the use of analgesic drugs that are devoidof these problems. Objective:- This study was done to compare the analgesic efficacy of Ketorolac and diclofenacin 60 adult patients of age group ranging between 30 to 45 years of age body wt 50-60kg belonging to ASA I and IIgrade. Material and Methods: Patients were scheduled for elective gynecological procedure (laparoscopic tuballigation) under general anaesthesia. They were divided into two equal groups using non-probability conveniencesampling technique. Each group comprised of 30 patients.

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Medina-Vera, A. J., and L. M. Novoa. "Disminución de los requerimientos anestésicos y analgésicos postoperatorios, en pacientes sometidos a colecistectomía laparoscópica: premedicación con paracetamol versus ketorolaco intravenoso, un estudio aleatorizado y doble ciego." Revista Española de Anestesiología y Reanimación 64, no. 2 (2017): 64–70. http://dx.doi.org/10.1016/j.redar.2016.05.007.

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Miliauskas, Povilas, Renatas Tikuišis, Saulius Cicėnas, Aleksas Žurauskas, and Narimantas Evaldas Samalavičius. "Potorakotominis intratekalinis skausmo malšinimas morfinu." Lietuvos chirurgija 5, no. 3 (2007): 0. http://dx.doi.org/10.15388/lietchirur.2007.3.2190.

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Povilas Miliauskas, Renatas Tikuišis, Saulius Cicėnas, Aleksas Žurauskas, Narimantas Evaldas SamalavičiusVilniaus universiteto Onkologijos institutas,Santariškių g. 1, LT-08660 VilniusEl paštas: povilas.miliauskas@gmail.com Įvadas / tikslas Šoninė torakotomija yra viena iš skausmingiausių operacijų. Šiame darbe nagrinėti ligonių, kuriems atliekamos plaučių operacijos, pooperacinio nuskausminimo aspektai. Buvo siekta palyginti intratekaliniu būdu ir į veną švirkščiamo morfino skausmo malšinamąjį efektyvumą po plaučių operacijos atliekant šoninę torakotomiją. Metodai Ligoniai, kuriems buvo atlie

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Gao, Bruce, Taylor Remondini, Navraj Dhaliwal, et al. "Incidence of bleeding in children undergoing circumcision with ketorolac administration." Canadian Urological Association Journal 12, no. 1 (2017): E6–9. http://dx.doi.org/10.5489/cuaj.4632.

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Introduction: Circumcision is the most common surgical procedure performed by pediatric urologists. Ketorolac has been shown to have an efficacy similar to morphine in multimodal analgesic regimens without the commonly associated adverse effects. Concerns with perioperative bleeding limit the use of ketorolac as an adjunct for pain control in surgical patients. As such, we sought to evaluate our institutional outcomes with respect to ketorolac and postoperative bleeding.Methods: We retrospectively reviewed all pediatric patients undergoing circumcision from January 1, 2014 to December 31, 2015

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Spowart, K., I. A. Greer, M. McLaren, J. Lloyd, R. E. S. Bullingham, and C. D. Forbes. "Haemostatic Effects of Ketorolac with and without Concomitant Heparin in Normal Volunteers." Thrombosis and Haemostasis 60, no. 03 (1988): 382–86. http://dx.doi.org/10.1055/s-0038-1646976.

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SummaryKetorolac is a potent cyclo-oxygenase inhibitor used for the treatment of postoperative pain. It is known to have anti-platelet properties. The aim of this study was to determine the effect of ketorolac on haemostasis both alone and in combination with tow dose heparin in LZ healthy male volunteers. Each volunteer received the following drug combinations in a double blind, placebo controlled, cross over manner: ketorolac placebo/heparin placebo, ketorolac active/heparin placebo, ketorolac active/heparin active and ketorolac placebo/heparin active. Ketorolac significantly prolonged bleed

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Park, Jun-Young, Jun Hyuk Hong, Jihion Yu, et al. "Effect of Ketorolac on the Prevention of Postoperative Catheter-Related Bladder Discomfort in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy: A Randomized, Double-Blinded, Placebo-Controlled Study." Journal of Clinical Medicine 8, no. 6 (2019): 759. http://dx.doi.org/10.3390/jcm8060759.

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Urinary catheterization can cause catheter-related bladder discomfort (CRBD). Ketorolac is widely used for pain control. Therefore, we evaluated the effect of ketorolac on the prevention of CRBD in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP). All patients were randomly allocated to the ketorolac group or the control group. The primary outcome was CRBD above a moderate grade at 0 h postoperatively. CRBD above a moderate grade at 1, 2, and 6 h was also assessed. Postoperative pain, opioid requirement, ketorolac-related complications, patient satisfaction, and hos

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Corelli, Robin L., and Kristin R. Gericke. "Renal Insufficiency Associated with Intramuscular Administration of Ketorolac Tromethamine." Annals of Pharmacotherapy 27, no. 9 (1993): 1055–57. http://dx.doi.org/10.1177/106002809302700908.

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OBJECTIVE: To evaluate reports of renal toxicity associated with intramuscular ketorolac tromethamine. Medical charts were reviewed for all cases of renal toxicity associated with ketorolac therapy. METHODS: Patients with possible ketorolac-associated nephrotoxicity were identified through our institution's adverse drug reaction reporting program. Patients were included in this report if: (1) renal insufficiency was temporally related to ketorolac administration; (2) resolution of renal insufficiency occurred after discontinuation of ketorolac; and (3) no other causes of renal insufficiency, i

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Stone, Sadie B. "Ketorolac in Postoperative Neonates and Infants: A Systematic Review." Journal of Pediatric Pharmacology and Therapeutics 26, no. 3 (2021): 240–47. http://dx.doi.org/10.5863/1551-6776-26.3.240.

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OBJECTIVE To evaluate the pharmacokinetics and pharmacodynamics, dosing, efficacy, and safety of ketorolac in postoperative patients younger than 6 months of age. METHODS PubMed (1988–July 2020), Medline (1946–July 2020), and EBSCO Discovery Service (1988–July 2020) were searched to identify relevant published articles using the following search terms: ketorolac, neonate, infant. English-language articles evaluating the use of ketorolac in infants younger than 6 months of age were included. RESULTS Eight reports that included 239 infants receiving ketorolac were included. Of the included patie

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Patri, Sabyasachi, Anil K. Patni, Sunil S. Iyer, et al. "A Validated High-Performance Liquid Chromatography-Tandem Mass Spectrometric (Lc-Ms/Ms) Method for Simultaneous Determination of R(+)-Ketorolac and S(−)-Ketorolac in Human Plasma and Its Application to a Bioequivalence Study." Chromatography Research International 2011 (November 30, 2011): 1–11. http://dx.doi.org/10.4061/2011/214793.

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We report a selective, accurate, and reproducible liquid chromatography-tandem mass spectrometric (LC-MS/MS) method that employs solid phase extraction for quantification of ketorolac enantiomers in human plasma. Resolution of R(+)-ketorolac and S(−)-ketorolac was achieved using a Chiral-AGP column and a mobile phase of ammonium formate buffer (10 mM, pH ):acetonitrile (85 : 15, v/v and 70 : 30, v/v) in a gradient time program. S(+)-etodolac was used as the internal standard (IS). Quantification was achieved using a positive electrospray ionization (ESI+) interface under multiple reaction moni

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Johansson, S., G. Josefsson, J. Malstam, A. Lindstrand, and A. Stenstroem. "Analgesic Efficacy and Safety Comparison of Ketorolac Tromethamine and Doleron for the Alleviation of Orthopaedic Post-Operative Pain." Journal of International Medical Research 17, no. 4 (1989): 324–32. http://dx.doi.org/10.1177/030006058901700404.

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The analgesic efficacy and safety of ketorolac tromethamine (ketorolac), a potent analgesic with anti-inflammatory and antipyretic activities, were evaluated and compared with Doleron, a combination analgesic, in 115 patients with moderate to severe orthopaedic post-operative pain. This was a randomized, double-blind (double-dummy), parallel-group comparison of a single oral dose of one capsule of 10 mg ketorolac with a single oral dose of two Doleron tablets (each tablet contained 150 mg dextropropoxyphene napsylate, 350 mg aspirin and 150 mg phenazone). During the 6 h following treatment, 80

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Kim, John S., Jon Kaufman, Sonali S. Patel, Marilyn Manco-Johnson, Jorge Di Paola, and Eduardo M. da Cruz. "Antiplatelet Effect of Ketorolac in Children After Congenital Cardiac Surgery." World Journal for Pediatric and Congenital Heart Surgery 9, no. 6 (2018): 651–58. http://dx.doi.org/10.1177/2150135118799041.

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Background: Ketorolac is used for pediatric analgesia after surgery despite its known platelet inhibition via the arachidonic acid (AA) pathway. The degree of platelet inhibitory effect after cardiac surgery is not well characterized. Thromboelastography with platelet mapping (TEG-PM) is emerging as a frequently used test to evaluate platelet inhibition via the AA pathway. Methods: Post hoc analysis of a data set collected in a prospective observational cohort study evaluating platelet inhibition in children after congenital heart surgery with cardiopulmonary bypass (CPB). Categorization into

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Cloesmeijer, M., E. Krekels, M. van Esdonk, et al. "P67 Impact of enantiomer-specific maturational changes in pharmacokinetics on the racemic ketorolac target trough concentration." Archives of Disease in Childhood 104, no. 6 (2019): e45.1-e45. http://dx.doi.org/10.1136/archdischild-2019-esdppp.105.

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IntroductionKetorolac is a racemic drug with analgesic effects specific to its S-enantiomer. This study aimed to describe enantiomer-specific maturational pharmacokinetics (PK). Simulations were performed to describe how S-ketorolac exposure in infants differs from adults, and how this affects the adult racemic analgesic trough threshold EC50 (EC50thr-adult, 0.37 mg/L) in infants (EC50thr-infant)when the same S-target is applied.MethodsA population PK analysis (NONMEM 7.3) was performed based on 1020 plasma samples from 5 studies including 80 patients (adults, children, infants) following sing

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Delaporte-Cerceau, Sonia, Charles-Marc Samama, Bruno Riou, Philippe Bonnin, Jean-Jacques Guillosson, and Pierre Coriat. "Ketorolac and Enoxaparin Affect Arterial Thrombosis and Bleeding in the Rabbit." Anesthesiology 88, no. 5 (1998): 1310–17. http://dx.doi.org/10.1097/00000542-199805000-00023.

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Background Nonsteroidal anti-inflammatory drugs (NSAIDs) may interfere with hemostasis during the perioperative period, and the combination of NSAID and enoxaparin could increase this effect. The aim of this prospective, blinded experimental study was to assess these effects using a model of arterial thrombosis and bleeding in the rabbit. Methods After anesthesia was induced and monitors placed, the common carotid arteries were exposed, and 60% stenosis of the right common carotid artery was produced. Twenty minutes later, a compression injury of the artery was produced that triggered a series

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Cairns, Brian E., Xu-Dong Dong, Hayes Wong, and Peter Svensson. "Intramuscular ketorolac inhibits activation of rat peripheral NMDA receptors." Journal of Neurophysiology 107, no. 12 (2012): 3308–15. http://dx.doi.org/10.1152/jn.01118.2011.

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The nonsteroidal anti-inflammatory drug (NSAID) diclofenac has local anesthetic-like and peripheral N-methyl-d-aspartate (NMDA) receptor antagonist characteristics when administered at higher concentrations to masticatory muscle. It is not known if the ability to inhibit NMDA receptors is unique to diclofenac or shared by other NSAIDs. This study was undertaken to determine whether intramuscular injection of ketorolac or naproxen at concentrations that do not induce local anesthetic-like effects could attenuate jaw-closer muscle nociceptor discharge in anesthetized Sprague-Dawley rats. It was

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Eisenach, James C., Regina Curry, Richard Rauck, Peter Pan, and Tony L. Yaksh. "Role of Spinal Cyclooxygenase in Human Postoperative and Chronic Pain." Anesthesiology 112, no. 5 (2010): 1225–33. http://dx.doi.org/10.1097/aln.0b013e3181d94dc0.

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Background Nonsteroidal antiinflammatory drugs are commonly used to treat postoperative and chronic pain. Animal studies suggest that these drugs act, in part, by blocking prostaglandin production in the spinal cord. The authors tested intrathecal ketorolac in patients with chronic or postoperative pain. Methods After approval of the institutional review board and the Food and Drug Administration, three clinical studies were performed. First, 15 patients receiving chronic intrathecal morphine received 0.5-2.0 mg of intrathecal ketorolac. Second, 12 patients receiving chronic intrathecal morphi

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 1263 (2009): 22. http://dx.doi.org/10.2165/00128415-200912630-00067.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 1314 (2010): 26. http://dx.doi.org/10.2165/00128415-201013140-00080.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 1316 (2010): 28. http://dx.doi.org/10.2165/00128415-201013160-00091.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 442 (1993): 10. http://dx.doi.org/10.2165/00128415-199304420-00043.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 442 (1993): 12. http://dx.doi.org/10.2165/00128415-199304420-00050.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 447 (1993): 9. http://dx.doi.org/10.2165/00128415-199304470-00039.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 454 (1993): 10. http://dx.doi.org/10.2165/00128415-199304540-00038.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 455 (1993): 10. http://dx.doi.org/10.2165/00128415-199304550-00044.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 460 (1993): 9. http://dx.doi.org/10.2165/00128415-199304600-00045.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 474 (1993): 8. http://dx.doi.org/10.2165/00128415-199304740-00034.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 432 (1992): 12. http://dx.doi.org/10.2165/00128415-199204320-00064.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 432 (1992): 16. http://dx.doi.org/10.2165/00128415-199204320-00091.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 433 (1993): 9. http://dx.doi.org/10.2165/00128415-199304330-00038.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 433 (1993): 10. http://dx.doi.org/10.2165/00128415-199304330-00043.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 436 (1993): 8. http://dx.doi.org/10.2165/00128415-199304360-00036.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 1091 (2006): 16. http://dx.doi.org/10.2165/00128415-200610910-00047.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 1109 (2006): 14. http://dx.doi.org/10.2165/00128415-200611090-00045.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 852 (2001): 10. http://dx.doi.org/10.2165/00128415-200108520-00031.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 858 (2001): 9. http://dx.doi.org/10.2165/00128415-200108580-00027.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 358 (1991): 9. http://dx.doi.org/10.2165/00128415-199103580-00047.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 536 (1995): 10. http://dx.doi.org/10.2165/00128415-199505360-00039.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 567 (1995): 8. http://dx.doi.org/10.2165/00128415-199505670-00024.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 577 (1995): 7. http://dx.doi.org/10.2165/00128415-199505770-00030.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 585 (1996): 8. http://dx.doi.org/10.2165/00128415-199605850-00033.

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&NA;. "Ketorolac." Reactions Weekly &NA;, no. 603 (1996): 7. http://dx.doi.org/10.2165/00128415-199606030-00021.

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