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Journal articles on the topic 'Keywords: non-toxic goiter and thyroid nodules'

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Published: 7 June 2025

Last updated: 2 August 2025

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1

Trinchera, Clint, and Emmanuel Tadeus Cruz. "Association of Ultrasonographic Findings and Thyroid Malignancy: A Cross-Sectional Study." Philippine Journal of Otolaryngology Head and Neck Surgery 34, no. 2 (2019): 24–28. http://dx.doi.org/10.32412/pjohns.v34i2.115.

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Objective: To determine the association of thyroid malignancy and the following ultrasonographic findings: presence of solid hypoechoic nodule, irregular margins (infiltrative, microlobulated, or speculated), microcalcifications or disrupted rim calcifications with small extrusive hypoechoic soft tissue component, taller than wide shape of the thyroid nodule, and evidence of extrathyroidal extension. Methods: Design: Cross-Sectional Study Setting: Tertiary Government Training Hospital Participants: Records of patients admitted to the Otorhinolaryngology- Head and Neck S

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Dalili, Setila, Daniel Zamanfar, Afagh Hassanzadeh Rad, and Saber Najafi Chakoosari. "Total Insights on Goiter in Children: A Mini-review." Journal of Pediatrics Review 10, no. 2 (2022): 145–54. http://dx.doi.org/10.32598/jpr.10.2.967.1.

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Background: Thyroid disorder is one of the main endocrine problems in childhood. In children with thyroid disorders, goiter is common. Objectives: In this mini-review, the authors aimed to present total insights on goiter in children. Methods: This is a mini-review about total insights on goiter in children. This review included articles assessing goiter in children. Web of Science, PubMed, and Google Scholar were investigated to find appropriate articles regarding goiter in children from 1988 to 2021. The keywords were thyroid, goiter, hyperthyroidism, hypothyroidism, and thyroid nodule. The

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Sabir, Farzana, Yasir Qayyum, Haseeb Ul Hassan, Attaullah Bangulzai, Fahad Bin Ghaffar, and Sania Sajjad. "Eventual Exploration of Thyroidal Surgical Treatment and its Obstacle Proportion Between Hundred Designated Instances." Pakistan Journal of Medical and Health Sciences 16, no. 1 (2022): 1031–33. http://dx.doi.org/10.53350/pjmhs221611031.

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Aim: In this eventual descriptive research the aim is to evaluate various obstacle of pancreatectomy and how to minimize the possible obstacles. Place and duration: For three years duration from December 2016 to November 2019, the research was led on 100 victims with thyroidal gland treated in the Department of Surgical treatment Unit II, Sir Ganga Ram Hospital Lahore. Methodology: Details have been added in a proforma. This research covers all thyroidal goiter instances and were hospitalized. Results: 10 had diff use toxic goitre; 3 victims had toxic multinodular goitre and 1 had toxic adenom

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Afridi, Muhammad Arif, Malik Mairaj Khalid, and Imran Khan. "DIAGNOSTIC CORRELATION OF ULTRASOUND AND THYROID FUNCTION TESTS IN EARLY THYROID DISEASES: A CROSS SECTIONAL STUDY." NORTHWEST JOURNAL OF MEDICAL SCIENCES 2, no. 4 (2023): 3–7. http://dx.doi.org/10.69723/njms.02.04.0351.

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BACKGROUND: Thyroid disease is a growing problem in young people and adolescents. Ultrasonography (US) serves as an optimal imaging modality for thyroid gland evaluation due to its ease of use, cost-effectiveness, non-invasiveness, and absence of ionizing radiation. It is used for detecting the growth of lumps in the neck or adjacent structures and serves as a valuable tool for uncovering thyroid gland abnormalities and detecting lesions that cannot be felt manually alongside the use of thyroid function tests. OBJECTIVES: The purpose of this study was to determine if thyroid function tests (TF

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Carsote, Mara, Mihai-Lucian Ciobica, Oana-Claudia Sima, et al. "Personalized Management of Malignant and Non-Malignant Ectopic Mediastinal Thyroid: A Proposed 10-Item Algorithm Approach." Cancers 16, no. 10 (2024): 1868. http://dx.doi.org/10.3390/cancers16101868.

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We aimed to analyze the management of the ectopic mediastinal thyroid (EMT) with respect to EMT-related cancer and non-malignant findings related to the pathological report, clinical presentation, imaging traits, endocrine profile, connective tissue to the cervical (eutopic) thyroid gland, biopsy or fine needle aspiration (FNA) results, surgical techniques and post-operatory outcome. This was a comprehensive review based on revising any type of freely PubMed-accessible English, full-length original papers including the keywords “ectopic thyroid” and “mediastinum” from inception until March 202

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ÇETİN, Zeynep, Derya KÖSEOĞLU, and Özden ÖZDEMİR BAŞER. "Clinical, sonographical and cytological comparison of toxic and non-toxic thyroid nodules." Journal of Health Sciences and Medicine 5, no. 3 (2022): 922–25. http://dx.doi.org/10.32322/jhsm.1089028.

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Aim: To compare patients with toxic and non-toxic nodular/multinodular goiter in terms of clinical, sonographical and cytological features. Material and Method: The medical data of 326 patients were reviewed retrospectively. Clinical and sonographic features were examined. Four hundred and eighty-one nodules were compared sonographically and cytologically. One hundred twenty-four patients had toxic nodular goiter and 202 of them had non-toxic nodular goiter. Results: The toxic nodular goiter group was older, they had more male sex, more multi-nodularity, larger thyroid glands and n

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Dederichs, B., C. Kobe, P. Theissen, M. Schmidt, H. Schicha, and M. Dietlein. "Therapy for non-toxic multinodular goiter." Nuklearmedizin 45, no. 01 (2006): 21–34. http://dx.doi.org/10.1055/s-0038-1623928.

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SummaryThe need for therapy for nodular goiter results from the growth of thyroid nodules over decades and from the possibility of tracheal compression and worsening of respiratory function. Given the high prevalence of non-toxic goiter, the epidemiologically low incidence of clinically apparent thyroid cancer justifies non-surgical strategies. Randomised studies have shown that levothyroxine offers limited therapeutic effects and is inferior to radioiodine therapy regarding goiter shrinkage. When indication for a definitive therapy is given, the choice between resection and radioiodine therap

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Khan, Salman, Muhammad Khizar Hayat, Omer Nasim, and Muhammad Shah Fahad. "Histopathological examination of thyroid specimens - a single center study from Peshawar, Khyber Pakhtunkhwa." Journal of Rehman Medical Institute 6, no. 1 (2020): 20–22. http://dx.doi.org/10.52442/jrmi.v6i1.205.

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Introduction: Thyroid gland enlargement is a surgical problem that affects about a third of the world's adults. Thyroid enlargement is best diagnosed by histopathology of surgical specimen and can also give a clue about different pattern of diseases that include simple goiter, multinodular goiter, thyroiditis, adenoma, and last but not the least, carcinoma. Objective: To determine presentation of thyroid lesions based on their histopathology in patients presenting to Rehman Medical Institute (RMI), Peshawar from August 2018 to July 2019. Materials & Methods: This was a descript

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Tyazhelova, O. V., and Vadym Khaziev. "FEATURES OF ULTRASOUND INVESTIGATION THYROID GLAND IN PATIENTS WITH RECURRENCE NODAL NON-TOXIC GOAT." Problems of Endocrine Pathology 38, no. 4 (2011): 18–22. http://dx.doi.org/10.21856/j-pep.2011.4.03.

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According to the ultrasound examination of patients with postoperative recurrent goiter, it was found that the signs for recurrence of single-node goiter are: oval shape of the tumor with clear contours, reduced echogenicity, absence of calcifications and fluid component, clear capsule. To optimize the tactics of surgical treatment of patients with nodules pathology of the thyroid gland, it is necessary to use intraoperative ultrasound examination of the neck, especially in multinodular goiter, when performing organ-preserving operations, as well as in malignant pathology of the thyroid

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Ali, Mohd Shahjahan, Md Habibullah Sarkar, and Syeda Momena Hossain. "Malignancy in Clinically Non-toxic Multinodular Goiter." Ibrahim Cardiac Medical Journal 10, no. 1-2 (2021): 84–88. http://dx.doi.org/10.3329/icmj.v10i1-2.54012.

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Objective: Goiter is a common form of thyroid swelling among population living in areas of iodine deficiency. Of the goiters, non-toxic multinodular goiter (MNG) is the most common and benign form of thyroid disease. However, studies have shown that long-standing MNGs may harbour malignancy. The present study was, therefore, undertaken to ascertain the prevalence of malignancy in clinically diagnosed non-toxic MNGs. Methods: This cross-sectional study was conducted in the Department of Surgery (all four-units) and ENT Department, Rajshahi Medical College Hospital, Rajshahi from July 2007

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Aqsha Madina and Anna Millizia. "Manajemen Anestesi Operasi Total Thyroidectomy Pada Pasien Struma Multinodosa: Laporan Kasus." Jurnal Anestesi 2, no. 3 (2024): 275–84. http://dx.doi.org/10.59680/anestesi.v2i3.1266.

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Goiter is an enlargement that occurs in the thyroid gland. Goiter can be classified based on physiology (euthyroidism, hypothyroidism, and hyperthyroisdism), morphology (diffuse and nodular goiter) and clinically (toxic and non-toxic goiter). Multinodular goiter is an enlargement of the thyroid gland with multiple nodules in which the thyroid gland follicles experience changes both morphologically and functionally. The characteristics of nontoxic multinodose goiter are slow, continuous and expanding growth. Surgery is one treatment for most types of goiter. The operation is performed under gen

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Ouattassi, Naouar, Mohammed Benlamlih, Nawal Hammas, and Mohamed Nour-Dine El Amine El Alami. "Primary Squamous Cell Carcinoma of the Thyroid Gland." Scholars Journal of Medical Case Reports 10, no. 2 (2022): 167–70. http://dx.doi.org/10.36347/sjmcr.2022.v10i02.031.

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Primary squamous cell carcinoma of the thyroid gland (ThSCC) is extremely rare. It accounts for less than 1% of thyroid malignancies with an aggressive behavior and poor prognosis. We report a case of an early stage ThSCC revealed through the histopathological findings of a total thyroidectomy for a non-toxic multinodular goiter. A 49 years old women presented with two years history of nodular goiter. Ultrasonography confirmed an enlarged thyroid gland with multiple nodules, one was ranked EU-TIRADS V without enlarged cervical lymph nodes. The patient underwent total thyroidectomy. Per operati

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Icha Hayuning Wulan, Ahmad Zakiudin, and Yusriani Saleh Baso. "Asuhan Keperawatan pada Nn. M dengan Gangguan Sistem Endokrin: Post Op Isthmolobektomi dengan Indikasi Struma Nodusa Non Toksik di Ruang Mawar 2 RSUD dr. Soeselo Kabupaten Tegal." Jurnal Anestesi 2, no. 4 (2024): 220–33. http://dx.doi.org/10.59680/anestesi.v2i4.1406.

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Non-toxic goiter nodusa is an enlargement of the thyroid gland in which one or more nodules are clinically detected without hyperthyroidism (Sari et al., 2021). The purpose of this writing is to find outand provide nursing care to Ms. M with endocrine system disorders: post op isthmolobectomy with indications of non-toxic nodal goiter in mawar ward 2 RSUD dr. Soeselo Tegal Regency in accordance with nursing standards. The method used is a descriptive method in the form of interviews, observation, documentation studies, library and literature studies. From the case review, it was found that the

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Rauf, Mohammad Talha, Winnie Nhan, and Farah Daneshvar. "Thyroid Tuberculosis Causing Fever of Unknown Origin in a Patient With Multinodular Goiter." Journal of the Endocrine Society 5, Supplement_1 (2021): A964—A965. http://dx.doi.org/10.1210/jendso/bvab048.1972.

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Abstract Introduction: Tuberculosis (TB) involving the thyroid gland is rare and typically results in hypothyroidism. Here we report a case of thyroid TB that presented with hyperthyroidism. Clinical Case: A 54-year-old woman with a history of hyperthyroidism due to toxic multinodular goiter presented to the emergency department with fever of unknown origin associated with sore throat, non-productive cough, night sweats, diarrhea, and right anterior neck pain that worsened with coughing. Her fevers were intermittent, ranging from 38 to 39 degrees Celsius, and would subside with acetaminophen.

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Muppidi, Keerthana, Vidya Kedarisetti, and Kanya Kumari Mahankali. "Correlation of Fine Needle Aspiration Cytology with Histopathological Findings in the Diagnosis of Thyroid Swellings – A One Year Study in a Tertiary Care Hospital, Hyderabad." Journal of Evidence Based Medicine and Healthcare 8, no. 18 (2021): 1246–51. http://dx.doi.org/10.18410/jebmh/2021/239.

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BACKGROUND Most of the thyroid swellings are non-neoplastic and with normal thyroid hormone. So, it doesn't require any surgical excision, even though the thyroid swelling is an indication for surgical excision. The present study was done to evaluate the accuracy of fine needle aspiration cytology (FNAC) for the thyroid swellings and correlate it with the histopathological findings. METHODS This is a prospective study. A total of 47 cases were studied. Fine needle aspiration cytology was done, slides were made and studied. Histopathological examination of the corresponding 47 cases was also do

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Devi, Banasri, Rachana Binayke, and Brizellda Dcunha. "Cytomorphological Profile of Thyroid Lesions on Fine Needle Aspiration Cytology." International Journal of Research and Review 8, no. 7 (2021): 218–22. http://dx.doi.org/10.52403/ijrr.20210730.

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Background and Objectives: Fine needle aspiration cytology (FNAC) of thyroid offers an alternative, as an immediate, preliminary procedure associated with low cost, little trauma and complications. Being superficial and easily accessible it is an ideal organ for FNAC. It is useful in diagnosis of inflammatory, infectious and neoplastic conditions. The aim of this study was to evaluate the cytomorphological profile of thyroid lesions on FNAC with application of Bethesda system for reporting and perform cyto-histopathology correlation whenever possible with regards to age and sex distribution. M

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Majid, M. A., and Md Ibrahim Siddique. "Major post-operative complications of thyroid surgery: Preventable or not?" Bangladesh Medical Research Council Bulletin 34, no. 3 (2009): 99–103. http://dx.doi.org/10.3329/bmrcb.v34i3.1973.

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Factors responsible for major complications following thyroid surgery in 598 patients were studied. Patients with non toxic multinodular goiter involving both lobes of thyroid constituted the maximum bulk subjected to thyroidectomy. The most frequent procedure was bilateral subtotal thyroidectomy. Reactionary hemorrhage occurred in 6 patients, all following bilateral procedures and among them 5 patients developed tension hematoma with respiratory obstruction despite the presence of a drain. Temporary vocal cord palsy was observed in 7 patients whereas one patient subjected to total thyroidecto

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Mohamed, Abubakr H. B., Faisal Qureshi, and Randa Sharag Eldin. "Solitary Fibrous Thyroid Tumor: A Case Report." Journal of the Endocrine Society 5, Supplement_1 (2021): A900—A901. http://dx.doi.org/10.1210/jendso/bvab048.1838.

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Abstract Introduction: Solitary fibrous thyroid nodules are rare tumors and can mimic benign thyroid goiter and neoplasms. Case Description45 years old Caucasian female, with no significant past medical history, who presented to endocrinologyclinic for left neck mass evaluation. She denied previous history of thyroid disease, weight loss, cold/heatintolerance, menstrual irregularity, toxic or obstructive thyroid related symptoms. Her family history issignificant for maternal pancreatic cancer. Clinical exam was unremarkable except for left thyroid mass. An initial thyroid ultrasound showed lef

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Villavicencio, Camila Alejandra, Alberto Franco-Akel, Regina Belokovskaya, et al. "Severe Hyperbilirubinemia Associated With Thyrotoxicosis: Importance of Early Recognition." Journal of the Endocrine Society 5, Supplement_1 (2021): A952—A953. http://dx.doi.org/10.1210/jendso/bvab048.1946.

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Abstract Thyroid storm (TS) is a rare and life-threatening condition due to a profound hypermetabolic state, leading to decompensation of homeostasis. It is commonly associated with a precipitating factor such as surgery, trauma, or infection. Occasionally, the clinical presentation may be non-specific, thus causing a potential delay in diagnosis. This could be problematic due to the condition’s high mortality rate, especially if not recognized early. Thyrotoxic jaundice presenting with a pattern of cholestatic hyperbilirubinemia (HBR) has been reported in the literature, although uncommon. We

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Coyne, Kasey, and Ioannis G. Papagiannis. "Severe Thyrotoxicosis Following Topical Iodine Application." Journal of the Endocrine Society 5, Supplement_1 (2021): A953—A954. http://dx.doi.org/10.1210/jendso/bvab048.1948.

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Abstract Background: Exposure to iodine can lead to iodine-induced hyperthyroidism in patients with underlying thyroid disease. Clinical Case: A 67 year-old woman with a history of nontoxic multinodular goiter and atrial fibrillation presented with fatigue, palpitations, weight loss, and tremor. Laboratory evaluation demonstrated new-onset profound biochemical hyperthyroidism (FT4 &gt; 7.77 ng/dL, n 0.8 – 1.8 ng/dL; FT3 &gt;27.0 pg/mL, n 2.0-4.4 pg/mL). She was treated with beta-blocker, high doses of methimazole, and cholestyramine while further evaluation was pursued. She declined SS

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Khaidarova, L.O. "WAYS TO IMPROVE THE OPERATION OF DIFFUSE-TOXIC GOITER IN THE ELDERLY AND SENILE PEOPLE." Research Focus International Scientific Journal 4, no. 1 (2025). https://doi.org/10.5281/zenodo.14808049.

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<strong>WAYS TO IMPROVE THE OPERATION OF DIFFUSE-TOXIC GOITER IN THE ELDERLY AND SENILE PEOPLE</strong> <strong>Khaidarova L.O.</strong> Samarkand State Medical University. Samarkand, Uzbekistan.<strong> </strong> <strong>https://doi.org/10.5281/zenodo.14808049</strong> <strong>Abstract:</strong> one of the pressing problems of modern medicine and endocrine surgery is the problem of the approach to surgical treatment of patients with toxic goiter. The relevance of this problem is associated with many issues affecting both the choice of surgical intervention and ways to reduce postoperative com

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"Treatment and Associated Factors of Surgically Treated Thyroid Disease at Bolan Medical College/Complex Hospital Quetta: A Retrospective Cross-sectional Study." Pakistan Journal of Medical and Health Sciences 17, no. 9 (2023). https://doi.org/10.53350/pjmhs2023170989.

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Objective: In this descriptive research, the objective is to assess the different challenges associated with pancreatectomy and to identify strategies for mitigating these potential obstacles. Methods: A Retrospective Cross-sectional Study was conducted for three years duration from December 2016 to November 2019. The research was led on 200 patients with thyroidal gland treated in the Department of Surgical treatment, Bolan Medical College/Complex Hospital, Quetta. Details have been added in a proforma and this research covers all thyroidal goiter instances in hospitalized pateints. Results:

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Narzullaev, Sh.Sh. "WAYS TO IMPROVE RESIDUAL THYROID TISSUE AFTER SURGERY FOR DIFFUSE TOXIC GOITTER IN THE ELDERLY AND SENILE PEOPLE." Research Focus International Scientific Journal 2, no. 10 (2023). https://doi.org/10.5281/zenodo.10005053.

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<strong>Abstract:</strong> one of the pressing problems of modern medicine and endocrine surgery is the problem of the approach to surgical treatment of patients with toxic goiter. The relevance of this problem is associated with many issues affecting both the choice of surgical intervention and ways to reduce postoperative complications and relapse of the disease. Surgical treatment of nontoxic goiter and thyroid nodules leads to a significant improvement in the quality of life of patients. The article examines the results of treatment of 128 patients for non-toxic goiter and thyroid nodules.

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Russo, D., S. Bulotta, R. Bruno, et al. "Sodium/iodide symporter (NIS) and pendrin are expressed differently in hot and cold nodules of thyroid toxic multinodular goiter." European Journal of Endocrinology, November 1, 2001, 591–97. http://dx.doi.org/10.1530/eje.0.1450591.

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OBJECTIVE: The expression of two iodide transporters, the sodium/iodide symporter (NIS) and pendrin, was analyzed in thyroid tissues of patients with toxic multinodular goiter (TMNG) and non-toxic multinodular goiter (MNG). METHODS: The levels of NIS and pendrin proteins were analyzed in total protein extracts from nodular and non-nodular tissues by Western blot. RESULTS: In tissue samples from TMNG, we found an increased expression of NIS (2.5-fold) in the hot nodules, and similar levels between cold nodules and non-nodular tissues. In contrast, the levels of pendrin were slightly increased i

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Russo, D., S. Bulotta, R. Bruno, et al. "Sodium/iodide symporter (NIS) and pendrin are expressed differently in hot and cold nodules of thyroid toxic multinodular goiter." January 24, 2005. https://doi.org/10.1530/eje.0.1450591.

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OBJECTIVE: The expression of two iodide transporters, the sodium/iodide symporter (NIS) and pendrin, was analyzed in thyroid tissues of patients with toxic multinodular goiter (TMNG) and non-toxic multinodular goiter (MNG). METHODS: The levels of NIS and pendrin proteins were analyzed in total protein extracts from nodular and non-nodular tissues by Western blot. RESULTS: In tissue samples from TMNG, we found an increased expression of NIS (2.5-fold) in the hot nodules, and similar levels between cold nodules and non-nodular tissues. In contrast, the levels of pendrin were slightly increased i

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Sheriba, Nermin Ahmed, Maram Mohamed Maher Mahdy, Dina Ahmed Marawan, and Ruwida Fouli Farag Mohamed Eljazwi. "Study of the Relation between 8_Hydroxy-2′-deoxyguanosin (8_OHDG) and Suspicious Thyroid Nodule in a Patients with Multinodular Goiter." QJM: An International Journal of Medicine 116, Supplement_1 (2023). http://dx.doi.org/10.1093/qjmed/hcad069.486.

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Abstract Background Nodular disease of the thyroid gland is prevalent. The lifetime risk for developing a palpable thyroid nodule is estimated to be 5-10%, however, high resolution ultrasound has revealed thyroid nodules in 19-68% of randomly selected individuals. The condition affects more women than men. Aim of the Work In this study we aimed to study the relation between 8_Hydroxy-2'deoxyguanosin (8_OHDG) and Suspicious Thyroid nodule in a Patients with Multinodular Goiter. Patients and Methods The present study was a case-control study that was conducted on 60 subjects patients presented w

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Lau, Lorraine W., Sana Ghaznavi, Alexandra D. Frolkis, et al. "Malignancy risk of hyperfunctioning thyroid nodules compared with non-toxic nodules: systematic review and a meta-analysis." Thyroid Research 14, no. 1 (2021). http://dx.doi.org/10.1186/s13044-021-00094-1.

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Abstract Background Hyperfunctioning or hot nodules are thought to be rarely malignant. As such, current guidelines recommend that hot nodules be excluded from further malignancy risk stratification. The objective of this systematic review and meta-analysis is to compare the malignancy risk in hot nodules and non-toxic nodules in observational studies. Methods Ovid MEDLINE Daily and Ovid MEDLINE, EMBASE, Scopus, and Web of Science databases were searched. Observational studies which met all of the following were included: (1) use thyroid scintigraphy for nodule assessment, (2) inclusion of bot

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Ji, Beisi, Omolara Adeniran, and Lina Soni. "THU661 Marine-Lenhart Syndrome: An Unusual Presentation Of Hyperthyroid Disease." Journal of the Endocrine Society 7, Supplement_1 (2023). http://dx.doi.org/10.1210/jendso/bvad114.1784.

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Abstract Disclosure: B. Ji: None. O. Adeniran: None. L. Soni: None. Background: Marine-Lenhart syndrome, also known as nodular Graves’ disease, is defined as the coexistence of functioning thyroid nodules and Graves’ disease. It is a rare syndrome, with a prevalence of approximately 0.8-2.7%. The two diseases may coexist or present at different times [1]. Treatment options include high doses of antithyroid medications or radioactive iodine and thyroidectomy in selected cases [2]. Clinical Case: A 72-year-old female with a medical history of right-sided breast cancer treated with lumpectomy and

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Bhadouria, Dharmendra Singh, Shikha Raghuwanshi, and Arun Saxena. "CYTO-HISTOPATHOLOGICAL CORRELATION OF THYROID LESIONS." International Journal of Medical and Biomedical Studies 5, no. 1 (2021). http://dx.doi.org/10.32553/ijmbs.v5i1.1664.

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Introduction: Thyroid nodules show an overall incidence rate of 4-7% & high probability of malignancy, constituting 5% to 35%. FNAC of Thyroid is most economical and reliable preoperative procedure to distinguish between neoplastic and non- neoplastic lesion. Objectives: To Study Cyto-Morphology of Fine Needle Aspiration of Thyroid nodules. To find out incidence of various types of lesions as per age & sex and to confirm the findings with Histomorphological diagnosis of same nodule. Material & Methods: 100 patients with Thyroid nodule who underwent FNAC & Thyroidect

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Agretti, P., G. De Marco, E. Ferrarini, et al. "Gene expression profile in functioning and non-functioning nodules of autonomous multinodular goiter from an area of iodine deficiency: unexpected common characteristics between the two entities." Journal of Endocrinological Investigation, August 17, 2021. http://dx.doi.org/10.1007/s40618-021-01660-y.

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Abstract Purpose Toxic multinodular goiter is a heterogeneous disease associated with hyperthyroidism frequently detected in areas with deficient iodine intake, and functioning and non-functioning nodules, characterized by increased proliferation but opposite functional activity, may coexist in the same gland. To understand the distinct molecular pathology of each entity present in the same gland, the gene expression profile was evaluated by using the Affymetrix technology. Methods Total RNA was extracted from nodular and healthy tissues of two patients and double-strand cDNA was synthesized.

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Andrikoula, M., G. Vartholomatos, GT Tsangaris, M. Bafa, F. Tzortzatou-Stathopoulou, and A. Tsatsoulis. "Fas and Bcl-2 protein expression in thyrocytes of patients with nodular goiter." European Journal of Endocrinology, October 1, 2001, 403–7. http://dx.doi.org/10.1530/eje.0.1450403.

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OBJECTIVE: The relative expression of the apoptotic protein Fas and the anti-apoptotic protein Bcl-2 were investigated in thyrocytes from patients with non-toxic nodular goiter (NTG, n=20) and Hashimoto's thyroiditis (HT, n=5), who underwent fine-needle aspiration biopsy for diagnostic reasons. On the basis of the clinical and cytological findings, the patients with NTG were sub-classified into the group of those with colloid nodules (n=9), degenerative nodules (n=6) and adenomatous nodules (n=5). METHODS: Fine-needle biopsy aspirates were examined by immunocytochemistry for Fas and Bcl-2 expr

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Godar, Cassandra M., Andrew J. Spiro, Mohamed K. M. Shakir, and Thanh D. Hoang. "SAT571 When Two Is Too Few: Bethesda IV Pathology On Repeat Thyroid Fine Needle Aspiration." Journal of the Endocrine Society 7, Supplement_1 (2023). http://dx.doi.org/10.1210/jendso/bvad114.2042.

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Abstract Disclosure: C.M. Godar: None. A.J. Spiro: None. M.K. Shakir: None. T.D. Hoang: None. Background: The 2015 American Thyroid Association Guidelines for Adult Patients with Thyroid Nodules provide a strong recommendation against routine ultrasound surveillance of thyroid nodules for which two benign fine needle aspiration (FNA) cytology results have been previously obtained. Strict adherence to these guidelines may hinder detection of malignancy, especially in large nodules where there is potential to miss heterogeneous pathology based on sampling technique. Clinical Case: A 36-year-old

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Sheremet, М. І., V. О. Shidlovskyy, Y. V. Girla, N. P. Tkachuk, A. G. Tibirna, and V. P. Dorosh. "SFas and FasL in etiopathogenesis of autoimmune diseases of the thyroid gland and nodular forms of goiter." December 5, 2015. https://doi.org/10.5281/zenodo.34845.

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Sheremet М. І., Shidlovskyy V. О., Girla Y. V., Tkachuk N. P., Tibirna A. G., Dorosh V. P. SFas and FasL in etiopathogenesis of autoimmune diseases of the thyroid gland and nodular forms of goiter. Journal of Education, Health and Sport. 2015;5(12):41-49. ISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.34845 <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2812%29%3A41-49</strong> <strong>http://pbn.nauka.gov.pl/works/675989</strong> <strong>Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014</strong> <strong>http://journal.rsw.edu.p

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Chartoumpekis, Dionysios, Panos Ziros, Cédric Renaud, et al. "OR28-01 Constitutive Activation of NRF2 Antioxidant Response Leads to Age-Dependent Goiter and Compensated Hypothyroidism in Male Mice." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.2042.

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Abstract Background: Familial non-toxic multinodular goiter (MNG) is a rare disease. KEAP1 gene (Kelch-like ECH-associated protein 1) that encodes the main inhibitor of nuclear factor erythroid 2-related transcription factor 2 (Nrf2), a central mediator of antioxidant responses, has been found to be one of the mutated genes that lead to familial MNG. The proposed association of KEAP1 with familial MNG is based on only two loss-of-function mutations in respective Japanese families, only one of which included proper phenotyping and demonstration of co-segregation of phenotype and mutation. To da

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Sheremet, M. I., V. O. Shidlovsky, and L. P. Sidorchuk. "Prevention of complications in remote period after operational treatment of patients with nodular goiter on background autoimmune thyroiditis." July 31, 2017. https://doi.org/10.5281/zenodo.1182684.

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Sheremet M. I., Shidlovsky V. O., Sidorchuk L. P. Prevention of complications in remote period after operational treatment of patients with nodular goiter on background autoimmune thyroiditis. Journal of Education, Health and Sport. 2017;7(7):1270-1284. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1182684 http://ojs.ukw.edu.pl/index.php/johs/article/view/5300         The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The A

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Kaur, Ravleen, Lavleen Kaur, Taibah Chaudhary, Mashu Shrivastava, and Nirali Patel. "6641 Observation in Lieu of Surgical Management in Hurthle Cell Neoplasm: Role of Thyroseq V3 Molecular Testing." Journal of the Endocrine Society 8, Supplement_1 (2024). http://dx.doi.org/10.1210/jendso/bvae163.2020.

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Abstract Disclosure: R. Kaur: None. L. Kaur: None. T. Chaudhary: None. M. Shrivastava: None. N. Patel: None. The diagnostic utility of fine needle aspiration biopsy with cytology is often confounded in thyroid nodules with predominance of hurthle cells, often interpreted as an oncocytic/hurthle cell lesion with intermediate risk of malignancy, bethesda category (BC) III or IV. With the advent of molecular testing like thyroseq V3, it is helpful in ruling out substantial risk of cancer and considering observation in lieu of surgical management in such difficult cases. We present a case of a 75

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Chen, Zhen, Meng-Li Guo, Ya-Yi Li, et al. "Immune profiling identifies CD8+ T-cell subset signatures as prognostic markers for recurrence in papillary thyroid cancer." Frontiers in Immunology 13 (November 7, 2022). http://dx.doi.org/10.3389/fimmu.2022.894919.

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BackgroundThyroid tissue has a special immune microenvironment that is not well characterized. Whether immune cells have a prognostic value in the recurrence of papillary thyroid cancer (PTC) needs further investigation.MethodsMultinodular non-toxic goiter (MNG) was taken as normal tissue for the difficulty in obtaining completely normal thyroid tissue (normal thyroid function, no thyroiditis, and no nodules). We compared the composition of mononuclear cells (MNCs) in peripheral blood and thyroid tissues from MNG and PTC patients by high-dimensional flow cytometry profiling and verified the re

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Vitkovskyi, O. O. "Clinical evaluation of the treatment complex of acute odontogenic periostitis in children on the base of diffused non-toxic goiter." Medicine Today and Tomorrow 91, no. 1 (2022). http://dx.doi.org/10.35339/msz.2022.91.1.vit.

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Inflammatory diseases in the maxillo-facial region in children occupy a leading place in the work of a polyclinic doctor. At the same time, their diagnosis is imperfect and they often occur on a premorbid background. The clinical features of acute odontogenic periostitis against the background of thyroid pathology in children were studied to improve the effectiveness of treatment. We examined 38 children, formed two groups of observations. Children of both groups were given generally accepted treatment. Children of the main group were additionally prescribed means "Imupret" and "Calcemin advan

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Kitsak, T. S. "The influence of thyroid pathology on the course of periodontal disease in children and ways to correct it (Review)." Medicine Today and Tomorrow 90, no. 3 (2021). http://dx.doi.org/10.35339/msz.2021.90.3.kit.

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Iodine deficiency diseases constitute an important medical and social problem, since a significant part of the territory of Ukraine is characterized by biogeochemical indicators of low iodine content in the environment, which is the cause of hypothyroidism development. At the same time, there are many other factors that can trigger the thyroid disorders in children. Epidemiological studies carried out in the Carpathian region have shown that iodine deficiency of varying degrees is specific to this area. Professor M.M. Kovalev's in-depth study of the causes of goitre in Bukovyna showed that alo

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Zhou, Ya, Kathryn Jobbins, and Raju Panta. "SAT-492 Impending Thyroid Storm Induced by Checkpoint Inhibitors." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.1149.

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Abstract Introduction: Thyroid storm is a rare but life threatening condition due to thyroid hormone excess and is usually caused by Graves disease, toxic nodular goiter or rarely due to thyroiditis. Immune checkpoint inhibitors (ICI) are a novel choice for treating cancers, and carry a risk for development of endocrinopathies. We report a case of impending thyroid storm 5 weeks after initiation of ICI. Case Presentation: 81-year-old Caucasian male with metastatic renal cell carcinoma presented with generalized weakness and fatigue 5 weeks after ipilimumab and nivolumab were started. He had no

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Thakkar, Aditi, Maria Camila Trejo-Parades, Anantha Sriharsha Madgula, and Margaret Stevenson. "SAT-470 When The Heart Can’t Clap To The Thyroid’s Beat." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.1182.

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Abstract Hyperthyroidism is associated with multiple cardiac pathologies including dilated cardiomyopathy, isolated right ventricular heart failure, and atrial fibrillation (AF). Long standing untreated hyperthyroidism in conjunction with AF can cause severe dilated cardiomyopathy with reduced ejection fraction that is completely reversible with treatment. We present the case of a previously healthy male who presented with florid congestive heart failure (CHF) as an initial presentation for hyperthyroidism. A 37-year-old male presented to the emergency department with progressively worsening d

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Ana Wolf, Ana Alice Wolf Maciel, Thais Freitas, Debora Lucia Seguro Danilovic, et al. "THU587 High Prevalence Of Primary Aldosteronism Diagnosis In Patients With Papillary Thyroid Cancer And Hypertension: A Cross-sectional Case-control Study." Journal of the Endocrine Society 7, Supplement_1 (2023). http://dx.doi.org/10.1210/jendso/bvad114.585.

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Abstract Disclosure: A.W. Maciel: None. T. Freitas: None. D.L. Danilovic: None. G.F. Fagundes: None. F. Freitas-Castro: None. L. Santana: None. A. Guimaraes: None. A. Pio-Abreu: None. J. V. Silveira: None. F. Consolim-Colombo: None. L. Bortolotto: None. M.C. Fragoso: None. A. Latronico: None. L. Drager: None. B.B. Mendonca: None. A.O. Hoff: None. M.Q. Almeida: None. Introduction: Aldosterone excess can cause oxidative stress leading to DNA damage in vitro and in vivo. Single case reports demonstrated a coincidence of primary aldosteronism (PA) with different malignancies. A higher prevalence o

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М.Ж., Еспенбетова, Жуманбаева Ж.М. та Глушкова Н.Е. "Семей қаласының Мемлекеттік медицина университеті, Жалпы дәрігерлік тәжірибе бойынша интернатура кафедрасы, Семей қ., Казахстан Республикасы". Наука и здравоохранение, № 2(19) (30 квітня 2017). http://dx.doi.org/10.34689/sh.2017.19.2.004.

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Кіріспе. Қалқанша бездің қатерсіз түзілістерін азинвазивті емдеу әдісі бойынша медициналық әдебиеттерге шолу жасауда онда қалқанша бездің солидті түйіндерін және кистозды түйіндерін емдеу кезінде эндокринолог және хирург дәрігерлерінің арасында консенсустың жоқтығын көрсетті. Зерттеудің мақсаты: Қалқанша бездің (ҚБ) қатерсіз түзілісі бар науқастарға тері арқылы этанолды инъекциялық терапияны (СКТ) қолдану болып табылды. Зерттеу әдістерімен материалдары: Бізбен осы науқастарға проспективті когротты зерттеу жүргізілді. Зерттеу кезеңі әр зерттеуге қатысушыға орташа 10±1,2 жылды құрайды. Жұмыс бас

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