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1

Tomlinson, Mark, Leslie Swartz, Peter J. Cooper, and Christopher Molteno. "Social Factors and Postpartum Depression in Khayelitsha, Cape Town." South African Journal of Psychology 34, no. 3 (September 2004): 409–20. http://dx.doi.org/10.1177/008124630403400305.

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Nleya, Ndodana, and Lisa Thompson. "Survey Methodology in Violence-prone Khayelitsha, Cape Town, South Africa." IDS Bulletin 40, no. 3 (May 2009): 50–57. http://dx.doi.org/10.1111/j.1759-5436.2009.00038.x.

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Swartz, Alison, Christopher Colvin, and Abigail Harrison. "The Cape Town boyfriend and the Joburg boyfriend: women’s sexual partnerships and social networks in Khayelitsha, Cape Town." Social Dynamics 42, no. 2 (May 3, 2016): 237–52. http://dx.doi.org/10.1080/02533952.2016.1194591.

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Bowden, Robyn, Etai Even-Zahav, and Candice Kelly. "Innovative Food Procurement Strategies of Women Living in Khayelitsha, Cape Town." Urban Forum 29, no. 3 (July 3, 2018): 315–32. http://dx.doi.org/10.1007/s12132-018-9338-3.

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Cremers, Anne Lia, René Gerrets, Christopher James Colvin, Monwabisi Maqogi, and Martin Peter Grobusch. "Tuberculosis patients and resilience: A visual ethnographic health study in Khayelitsha, Cape Town." Social Science & Medicine 209 (July 2018): 145–51. http://dx.doi.org/10.1016/j.socscimed.2018.05.034.

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Schneider, Marguerite, Emily Baron, Thandi Davies, Judith Bass, and Crick Lund. "Making assessment locally relevant: measuring functioning for maternal depression in Khayelitsha, Cape Town." Social Psychiatry and Psychiatric Epidemiology 50, no. 5 (January 8, 2015): 797–806. http://dx.doi.org/10.1007/s00127-014-1003-0.

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Jury, Catherine, and Nicoli Nattrass. "Parental presence within households and the impact of antiretroviral therapy in Khayelitsha, Cape Town." Southern African Journal of HIV Medicine 14, no. 2 (June 4, 2013): 70–74. http://dx.doi.org/10.4102/sajhivmed.v14i2.81.

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Background. While household support is an important component of effective care and treatment in HIV/AIDS, there are few insights from Southern Africa into how household support arrangements change over time for patients starting antiretroviral therapy (ART).Objective. We hypothesised that patients initiating ART are more likely to be living with family, especially their mothers, compared with the general population, but that over time these differences disappear.Methods. A panel survey of ART patients was matched by age, gender and education to a comparison sample drawn from adults in Khayelitsha, Cape Town.Results. The results show that there is a substantial potential burden of care on the families of patients starting ART, particularly mothers, and that the use of ART appears to reduce this burden over time. But, even after their health is restored, ART patients are significantly less likely to have a resident sexual partner and more likely to be living in single-person households than their counterparts in the general population.
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Mkabile, Siyabulela, and Leslie Swartz. "Caregivers’ and parents’ explanatory models of intellectual disability in Khayelitsha, Cape Town, South Africa." Journal of Applied Research in Intellectual Disabilities 33, no. 5 (March 30, 2020): 1026–37. http://dx.doi.org/10.1111/jar.12725.

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Smit, Warren, Ariane de Lannoy, Robert V. H. Dover, Estelle V. Lambert, Naomi Levitt, and Vanessa Watson. "Making unhealthy places: The built environment and non-communicable diseases in Khayelitsha, Cape Town." Health & Place 39 (May 2016): 196–203. http://dx.doi.org/10.1016/j.healthplace.2016.04.006.

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Ngxiza, Sonwabile. "Sustainable Economic Development in Previously Deprived Localities: The Case of Khayelitsha in Cape Town." Urban Forum 23, no. 2 (October 4, 2011): 181–95. http://dx.doi.org/10.1007/s12132-011-9134-9.

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Brijlal, Pradeep, and Albertina K. Jere. "Identifying and Exploiting Economic Opportunities : The Case of Unemployed Women in Khayelitsha Township, Cape Town." African Journal of Business and Economic Research 14, no. 2 (June 13, 2019): 5–23. http://dx.doi.org/10.31920/1750-4562/2019/14n2a1.

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Keikelame, Mpoe Johannah, and Leslie Swartz. "Parents' Understanding of the Causes and Management of Their Children's Epilepsy in Khayelitsha, Cape Town." South African Journal of Psychology 37, no. 2 (June 2007): 307–15. http://dx.doi.org/10.1177/008124630703700206.

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Jacobs, G. B., C. de Beer, J. E. Fincham, V. Adams, M. A. Dhansay, E. Janse van Rensburg, and S. Engelbrecht. "Serotyping and genotyping of HIV-1 infection in residents of Khayelitsha, Cape Town, South Africa." Journal of Medical Virology 78, no. 12 (2006): 1529–36. http://dx.doi.org/10.1002/jmv.20735.

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Skuse, Andrew, and Thomas Cousins. "Getting connected: the social dynamics of urban telecommunications access and use in Khayelitsha, Cape Town." New Media & Society 10, no. 1 (February 2008): 9–26. http://dx.doi.org/10.1177/1461444807085319.

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Pollio, Andrea. "Incubators at the Frontiers of Capital: An Ethnographic Encounter with Startup Weekend in Khayelitsha, Cape Town." Annals of the American Association of Geographers 110, no. 4 (December 4, 2019): 1244–59. http://dx.doi.org/10.1080/24694452.2019.1680232.

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Legg, Carol, and Claire Penn. "The Relevance of Context in Understanding the Lived Experience of Aphasia: Lessons from South Africa." Perspectives on Global Issues in Communication Sciences and Related Disorders 4, no. 1 (May 2014): 4–11. http://dx.doi.org/10.1044/gics4.1.4.

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Purpose: In this paper we describe a study of aphasia in a unique sociocultural context, to show the value of the anthropological perspective for the clinician faced with a diverse caseload. Methods: We present findings of an anthropological study of the experience of aphasia for adults living in Khayelitsha, a township on the outskirts of Cape Town, where the isiXhosa speaking residents live in conditions of poverty and where health and social resources are either lacking or in disarray (Legg, 2010). The study involved three years of intermittent fieldwork that included in-depth case studies of five adults living with aphasia in Khayelitsha and sustained contact with a number of healthcare and community institutions. Results: Interpretations and experiences of aphasia assumed a wider significance than communication disorder and were, essentially, a window onto the sociocultural and economic struggles that beset the lives of our participants. These struggles had profound influences on experiences of aphasia and responses to treatment. Conclusions: Understanding the unique contextual influences on experiences of aphasia will place the aphasia clinician in a more potent position to develop relevant interventions.
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Venables, Emilie, Catriona Towriss, Zanele Rini, Xoliswa Nxiba, Tali Cassidy, Sindiso Tutu, Anna Grimsrud, Landon Myer, and Lynne Wilkinson. "Patient experiences of ART adherence clubs in Khayelitsha and Gugulethu, Cape Town, South Africa: A qualitative study." PLOS ONE 14, no. 6 (June 20, 2019): e0218340. http://dx.doi.org/10.1371/journal.pone.0218340.

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Abrahams, Lucienne. "Innovation Entanglement at Three South African Tech Hubs." African Journal of Information and Communication, no. 26 (December 15, 2020): 1–29. http://dx.doi.org/10.23962/10539/30358.

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This study explores innovation modalities at three South African tech hubs: Bandwidth Barn Khayelitsha and Workshop 17 in Cape Town, and the Tshimologong Digital Innovation Precinct in Johannesburg. The study finds that tech start-ups’ability to scale is generally enhanced by their participation in the hubs. Furthermore, it is found that scaling by start-ups, and by the tech hubs hosting them, is enhanced when they actively drive the terms of their “entanglement” with exogenous and endogenous factors and external entities—a conceptual framework first developed in an earlier study of university research linkages (Abrahams, 2016). This present study finds that innovation entanglement by the hubs and their start-ups allows them to work through the adversity and states of complexity prevalent in their innovation ecosystems.
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Mohlakoana, Nthabiseng, and Wendy Annecke. "The use of liquefied petroleum gas by South African low-income urban households: A case study." Journal of Energy in Southern Africa 20, no. 4 (November 1, 2009): 2–10. http://dx.doi.org/10.17159/2413-3051/2009/v20i4a3306.

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At the end of 2005 and in 2006, the Western Cape suffered extended blackouts. The cuts came as a shock and customers were loud in their criticism of Eskom and the City of Cape Town’s failure to provide a reliable electricity supply. The utility Eskom’s responses included the introduction of an aggressive Demand Side Management (DSM) programme with the goal of saving electricity and reducing the need to shed customers. In Khayelitsha, Cape Town, the DSM programme entailed an exchange and subsidy programme: households were encouraged to swop their two-plate electric stoves for Liquid Petroleum Gas (LPG) stoves. This intervention is the subject of this paper. The results of the study were analysed in terms of the socio-economic characteristics of the sample interviewed, multiple fuel use and transition trends in households in urban areas, changes in behaviour in electricity and LPG use, changing perceptions of LPG and the impact of the intervention. Previous studies in household energy use showed that people perceived LPG to be dangerous saying that it posed a greater danger to the household than paraffin since it might explode. Surprisingly, during the electricity power cuts in 2006, people in low-income communities, readily accepted LPG stoves in great numbers and a year later, up to 89% of the households surveyed, reported still using LPG for cooking.
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Martín-González, Roberto, Kamilla Swart, and Ana-María Luque-Gil. "Tourism Competitiveness and Sustainability Indicators in the Context of Surf Tourism: The Case of Cape Town." Sustainability 13, no. 13 (June 28, 2021): 7238. http://dx.doi.org/10.3390/su13137238.

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Sport tourism has experienced considerable growth in the last decades, either from the sport events perspective or considering an active sport tourism approach. Therefore, some emergent market niches like surf tourism have been developed in numerous coastal destinations to attract sustainability-sensitive tourists due to the ongoing environmental challenges and the socio-economic crisis. Cape Town is positioned in a prominent place in terms of competitiveness, with a considerable variety of beaches and surf spots facing multiple issues. The aim of this study is to try to identify the most competitive beaches and subdistricts in terms of sustainability and to suggest criteria for surf-tourism-related indicators to obtain an overview about this space, using weighting indicators, and applying geography and political economy lenses. The results reveal that Strand, Table View, and Surfers’ Corner are the most competitive beaches. Additionally, beaches located in some underprivileged areas such as Mitchells Plain and Khayelitsha are potentially interesting from a socio-economic development point of view, although they show a lack of accommodation infrastructures. These results seem to indicate that those areas should be closely monitored, and destination managers should focus their attention and finance there to obtain a more sustainable surf tourism development.
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Barella, Jennifer. "Ramener la justice sociale au centre de la carte : propositions pour un renouvellement critique de la cartographie participative axée sur l'<i>empowerment</i>." Geographica Helvetica 75, no. 3 (September 4, 2020): 271–84. http://dx.doi.org/10.5194/gh-75-271-2020.

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Abstract. This paper discusses the need for a deeper critical interrogation of participatory mapping (PM) method as a tool for social justice. This stance is informed by the author's involvement in a NGO and community-led PM project in an informal settlement in Khayelitsha (Cape Town, South Africa). The paper argues that academic PM literature is ill-equipped to truly examine its potential for social justice. Firstly, this is due to the PM empowerment framework having shifted from an emancipatory aim to a governing tool. Secondly, this shift does not allow for the consideration of the power relations inherent to PM to be engaged with. This paper concludes by engaging the three epistemological and postcolonial roots of PM in order to provide a starting point for (re)centering PM on social justice.
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Crichton, H., N. O'Connell, H. Rabie, A. C. Whitelaw, and A. Dramowski. "Neonatal and paediatric bloodstream infections: Pathogens, antimicrobial resistance patterns and prescribing practice at Khayelitsha District Hospital, Cape Town, South Africa." South African Medical Journal 108, no. 2 (February 1, 2018): 99. http://dx.doi.org/10.7196/samj.2017.v108i2.12601.

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Crichton, H., N. O'Connell, H. Rabie, A. C. Whitelaw, and A. Dramowski. "Neonatal and paediatric bloodstream infections: Pathogens, antimicrobial resistance patterns and prescribing practice at Khayelitsha District Hospital, Cape Town, South Africa." South African Medical Journal 108, no. 2 (February 1, 2018): 99. http://dx.doi.org/10.7196/samj.2018.v108i2.12601.

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Ziervogel, Charlton, and Owen Crankshaw. "Inter-generational Occupational Mobility Amongst Blacks in the Mitchell’s Plain Magisterial District, Cape Town: Evidence from the Khayelitsha/Mitchell’s Plain Survey." Urban Forum 20, no. 2 (March 6, 2009): 235–51. http://dx.doi.org/10.1007/s12132-009-9062-0.

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Osman, Muhammad, Sue-Ann Meehan, Arne von Delft, Karen Du Preez, Rory Dunbar, Florian M. Marx, Andrew Boulle, Alex Welte, Pren Naidoo, and Anneke C. Hesseling. "Early mortality in tuberculosis patients initially lost to follow up following diagnosis in provincial hospitals and primary health care facilities in Western Cape, South Africa." PLOS ONE 16, no. 6 (June 14, 2021): e0252084. http://dx.doi.org/10.1371/journal.pone.0252084.

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In South Africa, low tuberculosis (TB) treatment coverage and high TB case fatality remain important challenges. Following TB diagnosis, patients must link with a primary health care (PHC) facility for initiation or continuation of antituberculosis treatment and TB registration. We aimed to evaluate mortality among TB patients who did not link to a TB treatment facility for TB treatment within 30 days of their TB diagnosis, i.e. who were “initial loss to follow-up (ILTFU)” in Cape Town, South Africa. We prospectively included all patients with a routine laboratory or clinical diagnosis of TB made at PHC or hospital level in Khayelitsha and Tygerberg sub-districts in Cape Town, using routine TB data from an integrated provincial health data centre between October 2018 and March 2020. Overall, 74% (10,208/13,736) of TB patients were diagnosed at PHC facilities and ILTFU was 20.0% (2,742/13,736). Of ILTFU patients, 17.1% (468/2,742) died, with 69.7% (326/468) of deaths occurring within 30 days of diagnosis. Most ILTFU deaths (85.5%; 400/468) occurred in patients diagnosed in hospital. Multivariable logistic regression identified increasing age, HIV positive status, and hospital-based TB diagnosis (higher in the absence of TB treatment initiation and being ILTFU) as predictors of mortality. Although hospitals account for a modest proportion of diagnosed TB patients they have high TB-associated mortality. A hospital-based TB diagnosis is a critical opportunity to identify those at high risk of early and overall mortality. Interventions to diagnose TB before hospital admission, improve linkage to TB treatment following diagnosis, and reduce mortality in hospital-diagnosed TB patients should be prioritised.
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Jabar, Ardil, Tolu Oni, Mark E. Engel, Nemanja Cvetkovic, and Richard Matzopoulos. "Rationale and design of the violence, injury and trauma observatory (VITO): the Cape Town VITO pilot studies protocol." BMJ Open 7, no. 12 (December 2017): e016485. http://dx.doi.org/10.1136/bmjopen-2017-016485.

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The establishment of violence and injury observatories elsewhere has been found to reduce the burden within a relatively short period. Currently no integrated system exists in South Africa to provide collated data on violence, to allow for targeted interventions and routine monitoring and evaluation.This research seeks to identify if bringing multiple data sources, including but not limited to data from the South African Police Service (SAPS), Forensic Pathology Services (FPS), Emergency Medical Services (EMS) and local hospital clinical databases, together are (1) feasible; (2) able to generate data for action, that is valid, reliable and robust and (3) able to lead to interventions.The violence, injury and trauma observatory (VITO) is a planned collaborative, multicentre study of clinical, police and forensic data for violence and injury in the City of Cape Town, where a local context exists of access to multiple source of health and non-health data. The VITO will initially be piloted in Khayelitsha, a periurban community characterised by increased rates of violence, where fatal and non-fatal injury data will be sourced from within the community for the period 2012–2015 and subjected to descriptive statistics and time-trend analyses. Analysed data will be visualised using story maps, data clocks, web maps and other geographical information systems-related products.This study has been approved by the University of Cape Town’s Human Research Ethics Committee (HREC 861/2016). We intend to disseminate our findings among stakeholders within the local government safety cluster, non-governmental organisations working within the violence prevention sector and the afflicted communities through the SAPS and violence prevention through urban upgrading community forums. Findings from this work will serve to identify important issues and trends, influence public policy and develop evidence-based interventions.
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Henwood, Ruth, Gabriela Patten, Whitney Barnett, Bella Hwang, Carol Metcalf, Damian Hacking, and Lynne Wilkinson. "Acceptability and use of a virtual support group for HIV-positive youth in Khayelitsha, Cape Town using the MXit social networking platform." AIDS Care 28, no. 7 (April 21, 2016): 898–903. http://dx.doi.org/10.1080/09540121.2016.1173638.

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Gibson, Diana, and Krishnavelli Nadasen. "‘I have plans’.Scrutinising the meaning, production and sustaining of hope in safe sexual practices among young men in Khayelitsha, Cape Town." Anthropology Southern Africa 30, no. 1-2 (January 2007): 1–10. http://dx.doi.org/10.1080/23323256.2007.11499941.

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Luque-Fernandez, Miguel Angel, Gilles Van Cutsem, Eric Goemaere, Katherine Hilderbrand, Michael Schomaker, Nompumelelo Mantangana, Shaheed Mathee, et al. "Effectiveness of Patient Adherence Groups as a Model of Care for Stable Patients on Antiretroviral Therapy in Khayelitsha, Cape Town, South Africa." PLoS ONE 8, no. 2 (February 13, 2013): e56088. http://dx.doi.org/10.1371/journal.pone.0056088.

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Reisach, Ulrike, and Mitja Weilemann. "Unternehmerische Sozialverantwortung deutscher Unternehmen in Südafrika." Der Betriebswirt: Volume 53, Issue 4 53, no. 4 (November 30, 2012): 34–36. http://dx.doi.org/10.3790/dbw.53.4.34.

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Die sozialen Probleme Südafrikas können nicht von der Politik alleine gemeistert werden. Das haben die großen intern internationalen Unternehmen in Südafrika längst erkannt und engagieren sich bei der Förderung von Schulen und Universitäten. Sie versorgen Schulen mit Mitteln und Ausstattung, um die nächste Generation mit dem auszustatten, was notwendig ist, um die großen gesellschaftlichen Herausforderungen dieses afrikanischen Landes zu bewältigen. Der Artikel basiert auf einem Projekt eines Team von der Hochschule Neu-Ulm, das sie in der Township von Khayelitsha in Kapstadt durchgeführt haben, und auf Interviews mit den verantwortlichen Unternehmensvertretern. Er erklärt wie BMW und T-Systems die Ausbildung von jungen Menschen unterstützen und ihnen ermöglicht, für ihre berufliche und persönliche Entwicklung zu lernen. Die Hürden, wie dabei zu überwinden sind, werden genauso aufgezeigt wie die Erfolge, die bereits erreicht wurden. The societal problems in South Africa cannot be mastered by politics alone. Foreign big companies are pace setters of progress in schools and universities. They provide schools with the skills and equipment to teach the next generation in what is necessary to overcome the huge societal and digital divide in the rainbow nation. The article is based on the research of a team from Neu-Ulm University of Applied Sciences in the township of Khayelitsha in Cape Town and on interviews with the responsible company representatives. It explains how BMW and T-Systems support the education of young people and enable them to learn for their professional and personal development. The hurdles which have to be overcome are shown as well as the achievements that have been accomplished. Keywords: „basic living skills“, t systems südafrika, cosat center for science and technology
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Lee, Jasper S., Cengiz Zopluoglu, Lena S. Andersen, Amelia M. Stanton, Jessica F. Magidson, Ashraf Kagee, John A. Joska, Conall O’Cleirigh, and Steven A. Safren. "Improving the measurement of food insecurity among people with HIV in South Africa: a psychometric examination." Public Health Nutrition 24, no. 12 (March 26, 2021): 3805–17. http://dx.doi.org/10.1017/s1368980021001312.

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AbstractObjective:Food insecurity is a structural barrier to HIV care in peri-urban areas in South Africa (SA), where approximately 80 % of households are moderately or severely food insecure. For people with HIV (PWH), food insecurity is associated with poor antiretroviral therapy adherence and survival rates. Yet, measurement of food insecurity among PWH remains a challenge.Design:The current study examines the factor structure of the nine-item Household Food Insecurity Access Scale (HFIAS, isiXhosa-translated) among PWH in SA using a restrictive bifactor model.Setting:Primary care clinics in Khayelitsha, a peri-urban settlement in Cape Town, SA.Participants:Participants (n 440) were PWH who received HIV care in Khayelitsha screening for a clinical trial. Most were categorised as severely (n 250, 56·82 %) or moderately (n 107, 24·32 %) food insecure in the past 30 d.Results:Revised parallel analysis suggested a three-factor structure, which was inadmissible. A two-factor structure was examined but did not adequately fit the data. A two-factor restrictive bifactor model was examined, such that all items loaded on a general factor (food insecurity) and all but two items loaded on one of two specific additional factors, which adequately fit the data (comparative fit index = 0·995, standardised root mean square residual = 0·019). The two specific factors identified were: anxiety/insufficient quality and no food intake. Reliability was adequate (ω = 0·82).Conclusions:Results supported the use of a total score, and identified two specific factors of the HFIAS, which may be utilised in future research and intervention development. These findings help identify aspects of food insecurity that may drive relationships between the construct and important HIV-related variables.
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Barnett, W., G. Patten, B. Kerschberger, K. Conradie, D. B. Garone, G. Van Cutsem, and C. KJ Colvin. "Perceived adherence barriers among patients failing second-line antiretroviral therapy in Khayelitsha, South Africa." Southern African Journal of HIV Medicine 14, no. 4 (November 22, 2013): 166–69. http://dx.doi.org/10.4102/sajhivmed.v14i4.51.

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Background. The recent scale-up of antiretroviral therapy (ART) coverage in resource-limited settings has greatly improved access to treatment. However, increasing numbers of patients are failing first- and second-line ART.Objective. To examine factors affecting adherence to second-line ART from the perspective of clinic staff and patients, assessing both individual and structural perceived barriers.Methods. Research was conducted at a large primary care tuberculosis (TB)/HIV clinic in Khayelitsha, a peri-urban township in Cape Town, South Africa. Participants were drawn from a Médecins Sans Frontières-run programme to support patients failing second-line ART. A qualitative research approach was used, combining multiple methodologies including key informant interviews with staff (n=11), in-depth interviews with patients (n=10) and a Photovoice workshop (n=11). Responses and photographs were coded by content; data were transformed into variables and analysed accordingly.Results. Staff identified drinking, non-disclosure, not using condoms and pill fatigue as barriers to ART adherence, while patients identified side-effects, not using condoms and a lack of understanding concerning medication timing. With respect to service delivery, staff identified a need for continued counselling and educational support following ART initiation. Patients were concerned about missing medical records and poor staff attitudes in the clinic.Conclusion. These findings identify discrepancies between provider and patient perceptions of barriers to, and facilitators of adherence, as well as of service delivery solutions. This highlights the need for on-going counselling and education following ART initiation, improved quality of counselling, and improved methods to identify and address specific barriers concerning medication adherence.
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Reuther, Sue, and Neil Dewar. "Competition for the use of public open space in low-income urban areas: the economic potential of urban gardening in Khayelitsha, Cape Town." Development Southern Africa 23, no. 1 (March 2006): 97–122. http://dx.doi.org/10.1080/03768350600556273.

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Oldfield, Sophie, Netsai Sarah Mathsaka, Elaine Salo, and Ann Schlyter. "In bodies and homes: Gendering citizenship in Southern African cities." Urbani izziv Supplement, no. 30 (February 17, 2019): 37–51. http://dx.doi.org/10.5379/urbani-izziv-en-2019-30-supplement-003.

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How do the everyday contexts in which ordinary women struggle to access and maintain a place on the peripheries of the city shape experiences of citizenship? This paper explores this question in George, a periurban Lusaka neighbourhood in Zambia and through experiences of Zimbabwean migrant women’s negotiation of a place on the peri-urban edges of Khayelitsha, Cape Town, South Africa. In the logics of citizen-subjects, the experiences of these groups of women should be poles apart, the first with rights imbued in citizenship, the second migrants without. Here instead, we demonstrate the ways in which gendered political subjectivities embed in the hard, lived realities of home. In placing gender and everyday body politics at the forefront of our analysis, the paper makes visible the micro-realities of making home. We demonstrate that an assumed recursive relationship between citizenship and home, as a physical and social place in the city, is problematic. Building on debates on citizenship and its gendering in post-colonial African urban contexts, we demonstrate instead that citizenship and its gendered contestations and emergent forms in Southern African are crafted in quotidian activities in homes and everyday city contexts.
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Roshan, Isaacs, and Puoane Thandi. "Can the Health Club be Used Effectively to Promote Healthy Lifestyles? A Comparison of Health Club Members and Community Controls in Khayelitsha, Cape Town." Journal of Life Sciences 3, no. 1 (July 2011): 57–64. http://dx.doi.org/10.1080/09751270.2011.11885170.

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Ladur, Alice Norah, Christopher J. Colvin, and Kathryn Stinson. "Perceptions of Community Members and Healthcare Workers on Male Involvement in Prevention of Mother-To-Child Transmission Services in Khayelitsha, Cape Town, South Africa." PLOS ONE 10, no. 7 (July 28, 2015): e0133239. http://dx.doi.org/10.1371/journal.pone.0133239.

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Möller, Anders, Luke Hunter, Lisa Kurland, Sa'ad Lahri, and Daniël J. van Hoving. "The association between hospital arrival time, transport method, prehospital time intervals, and in-hospital mortality in trauma patients presenting to Khayelitsha Hospital, Cape Town." African Journal of Emergency Medicine 8, no. 3 (September 2018): 89–94. http://dx.doi.org/10.1016/j.afjem.2018.01.001.

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Puoane, Thandi R., Lungiswa Tsolekile, Ehimario U. Igumbor, and Jean M. Fourie. "Experiences in Developing and Implementing Health Clubs to Reduce Hypertension Risk among Adults in a South African Population in Transition." International Journal of Hypertension 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/913960.

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Chronic noncommunicable diseases (NCDs) are increasing substantially as a cause of death and disability in all strata of the South African society, particularly among the urbanised poor. Hypertension is a risk factor for many of these diseases and becoming a burden in a growing population in a Cape Town township, Khayelitsha. To alleviate healthcare demands at clinics in this area, a health club was initiated and community health workers (CHWs) were trained to empower community members about NCDs and create public awareness. After training, a health club was initiated. Three months after initiation of the health club, 76 participants had been recruited of whom 22 were regular attenders. New members joined the health club weekly. Anthropometric and blood pressure measurements were taken, and various hypertension topics were covered at the club meetings which included healthy behaviours, such as the benefits of being physically active and eating healthy. Nutrition education sessions based on the South African food-based dietary guidelines were also held. Consequent to the initial group that was established, two more clubs were formed in the area. Health clubs are sustainable and culturally appropriate when facilitated by local people who have an insight and deeper understanding of the culture and environment of the people they serve.
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39

Connell, Tom G., Muki S. Shey, Ronnett Seldon, Molebogeng X. Rangaka, Gilles van Cutsem, Marcela Simsova, Zuzana Marcekova, et al. "Enhanced Ex Vivo Stimulation of Mycobacterium tuberculosis-Specific T Cells in Human Immunodeficiency Virus-Infected Persons via Antigen Delivery by the Bordetella pertussis Adenylate Cyclase Vector." Clinical and Vaccine Immunology 14, no. 7 (May 23, 2007): 847–54. http://dx.doi.org/10.1128/cvi.00041-07.

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ABSTRACTThe genetically detoxifiedBordetella pertussisadenylate cyclase is a promising delivery system for immunodominant tuberculosis antigens in gamma interferon release assays. This system has not been evaluated in human immunodeficiency virus (HIV)-infected persons in high tuberculosis prevalence areas. A whole-blood gamma interferon release assay withMycobacterium tuberculosisantigens (early-secreted antigenic target 6, culture filtrate protein 10, alpha-crystallin 2, and TB10.3) delivered by adenylate cyclase in addition to native tuberculosis antigens (without adenylate cyclase delivery) was evaluated in 119 adults in Khayelitsha Township, Cape Town, South Africa. Results were compared to tuberculin skin test results of 41 HIV-positive and 42 HIV-negative asymptomatic persons, in addition to 36 HIV-positive persons with recently diagnosed smear- or culture-positive pulmonary tuberculosis. Delivery of tuberculosis antigens by adenylate cyclase decreased by 10-fold the amount of antigen required to restimulate T cells. Furthermore, the responses of HIV-positive persons with a low response to native tuberculosis antigens were enhanced when these antigens were delivered by adenylate cyclase. When gamma interferon responses to the tuberculosis antigens (with or without delivery by adenylate cyclase) were combined, a significantly higher number of patients were scored positive than by tuberculin skin testing. Ex vivo responses to tuberculosis antigens delivered by adenylate cyclase are maintained in the context of HIV infection. Our findings suggest that the majority of those in this population are infected with tuberculosis, which is of significant public health importance.
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40

Masuku, Bianca, Nolwazi Mkhwanazi, Ed Young, Anastasia Koch, and Digby Warner. "Beyond the lab: Eh!woza and knowing tuberculosis." Medical Humanities 44, no. 4 (November 27, 2018): 285–92. http://dx.doi.org/10.1136/medhum-2018-011479.

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Eh!woza is a public engagement initiative that explores the biomedical and social aspects of tuberculosis (TB) in South Africa. The project is a collaboration between scientists based in an infectious disease research institute, a local conceptual/visual artist, a youth-based educational non-governmental organization (NGO) and young learners from a high-burden TB community. The learners participate in a series of interactive science and media production workshops: initially presented with biomedical knowledge about TB and, in later sessions, are trained in creating documentary films and engage with ideas around visual representation. The participants are encouraged to make use of this newly acquired knowledge to tell stories from their chosen communities in Khayelitsha, a township in Cape Town. Through its engagement with the complex manner in which TB is experienced, framed and understood by biomedical scientists, young people, and those who have been affected by the disease, Eh!woza presents alternative ways of exploring the complexities of human illness. The integration and interrogation of biomedical understandings, lay narratives and the young participants’ framing of the disease poses questions about ’knowing', and the meanings people attribute to ways of ’knowing' and the actions they impel. The project also presents contrasting reflections on cure—from a biomedical perspective, and care—from the perspective of TB-affected young people and community members. In this article, we describe the Eh!woza project, present thoughts from the participating students on the science and media workshops, and detail the narratives of ill-health and disease from people within their neighbourhoods. We conclude with a critical analysis of the complexities of knowledge communication, notions of cure versus care, and a consideration of the potential contribution of this project to the growth of medical humanities in Africa.
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Griesel, Rulan, Andrew Hill, Graeme Meintjes, and Gary Maartens. "Standard versus double dose dolutegravir in patients with HIV-associated tuberculosis: a phase 2 non-comparative randomised controlled (RADIANT-TB) trial." Wellcome Open Research 6 (January 11, 2021): 1. http://dx.doi.org/10.12688/wellcomeopenres.16473.1.

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Dolutegravir, a second-generation integrase strand transfer inhibitor (InSTI), is replacing efavirenz as first-line antiretroviral therapy (ART) in low middle-income countries (LMICs). Tuberculosis remains the leading cause of HIV-related morbidity and mortality in LMICs. Rifampicin is a key agent in the treatment of tuberculosis but induces genes involved in dolutegravir metabolism and efflux. The resulting drug-drug interaction (DDI) reduces the exposure of dolutegravir. However, this can be overcome by supplying a supplemental dose of 50 mg dolutegravir 12 hours after the standard daily dose, which is difficult to implement in LMICs. Four lines of evidence suggest that the supplemental dose may not be necessary: 1) a phase 2 study showed 10 mg of dolutegravir as effective as 50 mg; 2) the prolonged dissociative half-life of dolutegravir after binding to its receptor; 3) a DDI study reported dolutegravir trough concentrations were maintained above its minimum effective concentration when using 50 mg dolutegravir with rifampicin; and 4) virologic outcomes were similar between standard and double dose of raltegravir (a first-generation InSTI) in participants with HIV-associated tuberculosis treated with rifampicin. We hypothesise that virologic outcomes with standard dose dolutegravir-based ART will be acceptable in patients on rifampicin-based antituberculosis therapy. Here we outline the protocol for a phase 2, non-comparative, randomised, double-blind, placebo-controlled trial of standard versus double dose dolutegravir among adults living with HIV (ART naïve or first-line interrupted) on rifampicin-based antituberculosis therapy. A total of 108 participants will be enrolled from Khayelitsha in Cape Town, South Africa. Follow up will occur over 48 weeks. The primary objective is to assess proportion virological suppression at 24 weeks between groups analysed by modified intention to treat. Participant safety and the emergence of antiretroviral resistance mutations among those with virologic failure will be assessed throughout. Trial registrations: clinicaltrials.gov NCT03851588 (22/02/2019), SANCTR DOH-27-072020-8159 (03/07/2020).
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42

Zhao, Ying, Claire Keene, Rulan Griesel, Kaneez Sayed, Zimasa Gcwabe, Amanda Jackson, Olina Ngwenya, et al. "AntiRetroviral Therapy In Second-line: investigating Tenofovir-lamivudine-dolutegravir (ARTIST): protocol for a randomised controlled trial." Wellcome Open Research 6 (February 17, 2021): 33. http://dx.doi.org/10.12688/wellcomeopenres.16597.1.

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Background: Dolutegravir has superior efficacy and tolerability than lopinavir-ritonavir in second-line antiretroviral therapy after failure of a first-line non-nucleoside reverse transcriptase inhibitors-based regimen, when dolutegravir is accompanied by at least one fully active nucleoside reverse transcriptase inhibitor (NRTI). Resistance testing to select NRTIs is not feasible in low- and middle-income countries due to cost and limited laboratory capacity. Evidence suggests that recycling tenofovir plus lamivudine or emtricitabine backbone with dolutegravir could provide an effective second-line option. This study aims to determine the virologic efficacy of tenofovir-lamivudine-dolutegravir (TLD) with and without a lead-in supplementary dose of dolutegravir (to counteract the inducing effect of efavirenz) in patients failing a first-line regimen of tenofovir-emtricitabine-efavirenz (TEE). Methods: We will perform a parallel group, randomised (1:1), double blind, placebo-controlled, Phase II trial, comparing TLD fixed dose combination daily with a lead-in supplementary 50 mg dolutegravir dose versus matching placebo taken 12 hours later for the first 14 days, in patients failing a first-line TEE regimen. The trial will be set in two primary care clinics in Khayelitsha; a large, peri-urban informal settlement in Cape Town, South Africa. We will enrol 130 participants, with follow-up to 48 weeks. The primary endpoint is proportion achieving viral load <50 copies/mL at week 24 using a modified intention-to-treat analysis and the U.S. Food and Drug Administration snapshot algorithm. Secondary endpoints include virologic suppression at weeks 12 and 48, time to suppression, emergence of dolutegravir and new NRTI resistance mutations, safety, and tolerability. Discussion: Impaired viral fitness due to NRTI resistance mutations and dolutegravir’s high barrier to resistance provide rationale for switching patients from a failing TEE regimen to TLD; however, clinical evidence regarding virologic efficacy is lacking. This study provides estimates of such a strategy’s early virologic efficacy with and without a supplementary dolutegravir dosing. Registration: ClinicalTrials.gov NCT03991013 (19/06/2019).
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43

Donaldson, Ronnie, and Danie Du Plessis. "The urban renewal programme as an area-based approach to renew townships: The experience from Khayelitsha's Central Business District, Cape Town." Habitat International 39 (July 2013): 295–301. http://dx.doi.org/10.1016/j.habitatint.2012.10.012.

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44

Stinson, Kathryn, Eric Goemaere, David Coetzee, Gilles van Cutsem, Katherine Hilderbrand, Meg Osler, Claudine Hennessey, et al. "Cohort Profile: The Khayelitsha antiretroviral programme, Cape Town, South Africa." International Journal of Epidemiology, May 20, 2016, dyw057. http://dx.doi.org/10.1093/ije/dyw057.

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45

Faull, Andrew. "On the record: Interview with Phumeza Mlungwana, Social Justice Coalition." South African Crime Quarterly, no. 56 (June 28, 2016). http://dx.doi.org/10.17159/2413-3108/2016/v0i56a1289.

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In March this year a prominent South African grassroots organisation, the Social Justice Coalition (SJC), announced that it would be taking the South African Police Service (SAPS) to court. Andrew Faull spoke to the SJC’s General Secretary, Phumeza Mlungwana, about crime and policing in Khayelitsha, Cape Town.
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46

Faull, Andrew. "On the record: Interview with Phumeza Mlungwana, Social Justice Coalition." South African Crime Quarterly, no. 56 (June 28, 2016). http://dx.doi.org/10.17159/2413-3108/2016/v0n56a1289.

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In March this year a prominent South African grassroots organisation, the Social Justice Coalition (SJC), announced that it would be taking the South African Police Service (SAPS) to court. Andrew Faull spoke to the SJC’s General Secretary, Phumeza Mlungwana, about crime and policing in Khayelitsha, Cape Town.
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47

Houmøller, Kathrin. "Steder smitter: hiv, aids-medicin og tavshedens sociale liv i Khayelitsha." Tidsskrift for Forskning i Sygdom og Samfund 14, no. 26 (May 4, 2017). http://dx.doi.org/10.7146/tfss.v14i26.26287.

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Denne artikel undersøger, hvordan tavshed udspiller sig i hverdagslivet i Khayelitsha township i Cape Town, Sydafrika, og hvad der driver dens udbredelse. I Sydafrika lever 5,6 millioner mennesker med hiv, og landet har verdens største aids- behandlingsprogram. Et udbredt fravær af mellemmenneskelig kommunikation om hiv og aids har ført til, at aids-epidemien i Sydafrika har været beskrevet som en epidemi af tavshed. Mens tidligere studier har fokuseret på smittevejen mellem tavshed og den sociale betydning af hiv og aids som en dødelig og stigmatiserende sygdom, belyser artiklen, hvordan tavshed også skal forstås i dens forbindelse til Khayelitsha som et specifikt sted, der intensiverer særlige vilkår for tavshed som en form for socialitet, der ikke er særlig for hiv og aids. Med et perspektiv på social smitte er det således artiklens argument, at det også er selve stedet - et hverdagsliv i tvungen intimitet – der smitter. Place is Contagious: hiv, aids medicine and the social life of silence in KhayelitshaThis article explores practices of silence in Khayelitsha township in Cape Town, South Africa, and seeks to investigate what drives silence as a widespread phenomenon. In South Africa, 5,6 million people are currently living with hiv and the country has the largest aids treatment programme in the world. The aids epidemic has often been paralleled to an epidemic of silence with reference to a significant absence of direct verbal communication about the disease. While previous studies have focused on the connection between silence and the association of hiv with death and stigma, the article argues that the spread of silence cannot be understood disconnected from Khayelitsha as a particular place that intensifies silence as a form of sociality not specific to hiv and aids. From a perspective on social contagion, the article argues that it is also the place itself – an everyday life in enforced intimacy – that is contagious.
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48

Nattrass, Nicoli, Jed Stephens, and Jorich Johann Loubser. "Animal welfare and ecology in the contested ethics of rodent control in Cape Town." Journal of Urban Ecology 5, no. 1 (January 1, 2019). http://dx.doi.org/10.1093/jue/juz008.

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Abstract There is growing concern globally about the inhumane treatment of ‘pest’ animals, including rodents, and about the ecological consequences of rodenticides, notably the poisoning of non-target wildlife like raptors and scavengers. Recent contestation between Environmental Health (EH) officials in Khayelitsha, Cape Town’s largest African township, and the National Council for Societies for the Prevention of Cruelty to Animals (NSPCA) illustrates the tension that can arise between innovative ecologically-focused strategies and existing legislation and animal protection practices. In 2013/14 EH officials introduced a job-creation project to trap and drown rats, describing it as ‘humane’ because it avoided poison thereby posing no danger to wildlife such as owls. The NSPCA, however, halted the project, arguing that drowning was both inhumane and illegal. Death by poison is also inhumane but the South Africa’s Animals Protection Act (1962) allows it (and trapping and hunting) to be used against ‘pests’/‘vermin’. The NSPCA, which has never challenged the Act for allowing the inhumane treatment of these animals, used it to trump local preferences. A representative survey from Khayelitsha showed that there was some support for an NSPCA-like position (14% thought that drowning was cruel and that workers should not be allowed to trap and drown rats) but that the majority (70%) indicated that they were both concerned about the poisoning of non-target animals and supported the continuation of the trapping and drowning project. This was not a contestation over whether animals should be protected, but over how to do this, and which animals to include.
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Freer, Joseph, Hassan Mahomed, and Anthony Westwood. "Prevention, Management and Risk Factors for Diarrhoeal Disease in under-Fives in Cape Town." Journal of Tropical Pediatrics, July 26, 2020. http://dx.doi.org/10.1093/tropej/fmaa036.

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Abstract Background In South Africa, Cape Town’s health facilities are stretched by the volume of cases of diarrhoea during the summer months, particularly with severely dehydrated children, who often require complex inpatient management. The prevalence of severe disease in children living in the settlements around Cape Town is particularly high. Methods An observational study of a systematic sample of children under 5 who presented to any primary care facility in Khayelitsha, an informal settlement of Cape Town, with diarrhoea and referred to secondary care between 1 November 2015 and 30 April 2016. We recruited participants from the sub-district office and identified risk factors associated with the index presentation, captured the triage and management of patients in primary care and investigated post-discharge follow-up. Results We recruited 87 children into the study, out of a total of 115 cases of severe dehydration. There was a significantly higher number of households in this group with no income than in Khayelitsha overall (65% vs. 47.4%; p &lt; 0.001). In the sample, HIV-exposed, uninfected children were younger than unexposed children (median 9.44 months in exposed vs. 17.36 months in unexposed; p = 0.0015) and were more likely to be malnourished (weight-for-age Z-score; WAZ score &lt; −2) [13 cases exposed vs. 8 cases unexposed (p = 0.04)]. Outreach staff were able to trace only 33.3% of children at home following discharge, yet 65% of children attended follow-up appointments in clinics. Conclusions This cohort of children with diarrhoeal disease complicated by severe dehydration was a particularly socially deprived group. The results demonstrating zero vertical transmission of HIV in this very socioeconomically deprived area of Cape Town are encouraging. In the HIV-exposed, uninfected group, children were younger and had a higher prevalence of malnutrition, which should be the subject of future research, especially given existing evidence for immunological differences in children exposed to HIV in utero. Locating children with severe diarrhoea post-discharge was challenging and further research is needed on the cost-effectiveness and outcomes of different follow-up approaches.
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Webb, Christopher. "“These aren’t the jobs we want”: youth unemployment and anti-work politics in Khayelitsha, Cape Town." Social Dynamics, June 7, 2021, 1–17. http://dx.doi.org/10.1080/02533952.2021.1906148.

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