Relevant bibliographies by topics / Kidney; Nervous system; Tyrosine kinase

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Kidney; Nervous system; Tyrosine kinase'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Kidney; Nervous system; Tyrosine kinase.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Kidney; Nervous system; Tyrosine kinase"

1

Jijiwa, Mayumi, Toshifumi Fukuda, Kumi Kawai, et al. "A Targeting Mutation of Tyrosine 1062 in Ret Causes a Marked Decrease of Enteric Neurons and Renal Hypoplasia." Molecular and Cellular Biology 24, no. 18 (2004): 8026–36. http://dx.doi.org/10.1128/mcb.24.18.8026-8036.2004.

Full text
Abstract:
ABSTRACT The Ret receptor tyrosine kinase plays a crucial role in the development of the enteric nervous system and the kidney. Tyrosine 1062 in Ret represents a binding site for the phosphotyrosine-binding domains of several adaptor and effector proteins that are important for the activation of intracellular signaling pathways, such as the RAS/ERK, phosphatidylinositol 3-kinase/AKT, and Jun-associated N-terminal kinase pathways. To investigate the importance of tyrosine 1062 for organogenesis in vivo, knock-in mice in which tyrosine 1062 in Ret was replaced with phenylalanine were generated.
APA, Harvard, Vancouver, ISO, and other styles
2

Schuchardt, Anita, Vivette D'Agati, Lena Larsson-Blomberg, Frank Costantini, and Vassilis Pachnis. "Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret." Nature 367, no. 6461 (1994): 380–83. http://dx.doi.org/10.1038/367380a0.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Wong, Adrianne, Silvia Bogni, Pille Kotka, et al. "Phosphotyrosine 1062 Is Critical for the In Vivo Activity of the Ret9 Receptor Tyrosine Kinase Isoform." Molecular and Cellular Biology 25, no. 21 (2005): 9661–73. http://dx.doi.org/10.1128/mcb.25.21.9661-9673.2005.

Full text
Abstract:
ABSTRACT The receptor tyrosine kinase Ret plays a critical role in the development of the mammalian excretory and enteric nervous systems. Differential splicing of the primary Ret transcript results in the generation of two main isoforms, Ret9 and Ret51, whose C-terminal amino acid tails diverge after tyrosine (Y) 1062. Monoisoformic mice expressing only Ret9 develop normally and are healthy and fertile. In contrast, animals expressing only Ret51 have aganglionosis of the distal gut and hypoplastic kidneys. By generating monoisoformic mice in which Y1062 of Ret9 has been mutated to phenylalani
APA, Harvard, Vancouver, ISO, and other styles
4

Dawson, D. M., E. G. Lawrence, G. MacLennan, and T. G. Pretlow. "C-Ret Proto-Oncogene Expression in Human Prostate: An Immunohistochemical Evaluation." Microscopy and Microanalysis 3, S2 (1997): 21–22. http://dx.doi.org/10.1017/s1431927600006991.

Full text
Abstract:
C-ret proto-oncogene encodes a protein in the tyrosine kinase (TK) family of transmembrane receptors for growth factors. C-ret expression has been identified in normal tissues and tumors of neural crest origin such as inherited MEN (multiple endocrine neoplasia) syndromes, particularly medullary thyroid cancers where there are confirmed germ-line mutations. Gene rearrangement has been observed in papillary thyroid carcinomas (PTC) and has been shown to have cytoplasmic localization of the altered gene product. C-ret proto-oncogene product is also necessary for the normal development of the per
APA, Harvard, Vancouver, ISO, and other styles
5

Pachnis, V., B. Mankoo, and F. Costantini. "Expression of the c-ret proto-oncogene during mouse embryogenesis." Development 119, no. 4 (1993): 1005–17. http://dx.doi.org/10.1242/dev.119.4.1005.

Full text
Abstract:
The c-ret proto-oncogene encodes a receptor tyrosine kinase whose normal function has yet to be determined. To begin to investigate the potential role of this gene in vertebrate development, we have isolated cDNA clones representing the murine c-ret gene, and have analyzed the pattern of expression during mouse embryogenesis, using northern blotting, in situ hybridization to histological sections and whole-mount hybridization histochemistry. c-ret transcripts were detected beginning at day 8.5 of embryogenesis, and were observed in a number of cell lineages in the developing peripheral and cen
APA, Harvard, Vancouver, ISO, and other styles
6

Mungunsukh, Ognoon, Young H. Lee, Ana P. Marquez, Fabiola Cecchi, Donald P. Bottaro, and Regina M. Day. "A tandem repeat of a fragment of Listeria monocytogenes internalin B protein induces cell survival and proliferation." American Journal of Physiology-Lung Cellular and Molecular Physiology 299, no. 6 (2010): L905—L914. http://dx.doi.org/10.1152/ajplung.00094.2010.

Full text
Abstract:
Hepatocyte growth factor (HGF) is critical for tissue homeostasis and repair in many organs including the lung, heart, kidney, liver, nervous system, and skin. HGF is a heterodimeric protein containing 20 disulfide bonds distributed among an amino-terminal hairpin, four kringle domains, and a serine protease-like domain. Due to its complex structure, recombinant production of HGF in prokaryotes requires denaturation and refolding, processes that are impractical for large-scale manufacture. Thus, pharmaceutical quantities of HGF are not available despite its potential applications. A fragment o
APA, Harvard, Vancouver, ISO, and other styles
7

Oishi, Isao, Shin Sugiyama, Zhao-Jun Liu, Hirohei Yamamura, Yasuyoshi Nishida, and Yasuhiro Minami. "A NovelDrosophilaReceptor Tyrosine Kinase Expressed Specifically in the Nervous System." Journal of Biological Chemistry 272, no. 18 (1997): 11916–23. http://dx.doi.org/10.1074/jbc.272.18.11916.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Hattori, Seisuke, Shoichiro Kanda, and Yutaka Harita. "Tyrosine Kinase Signaling in Kidney Glomerular Podocytes." Journal of Signal Transduction 2011 (May 30, 2011): 1–10. http://dx.doi.org/10.1155/2011/317852.

Full text
Abstract:
During the last decade, several key molecules have been identified as essential components for the filtration barrier function of kidney glomerular podocytes. Mutations in genes encoding these molecules severely impair the podocyte architecture in the affected patients, leading to the development of proteinuria. Extensive investigations have been performed on the function of these molecules, which highlights the importance of tyrosine kinase signaling in the podocytes. An Src family tyrosine kinase, Fyn, plays a major role in this signaling pathway. Here, we review the current understanding of
APA, Harvard, Vancouver, ISO, and other styles
9

Bertram, Andrea E., Robert J. Dugand, Clodagh Guildea, et al. "Renal corpuscle and tubule morphology in ephrin-A2-/-, ephrin-A5-/- and ephrin-A2A5-/- mice." F1000Research 2 (October 11, 2013): 212. http://dx.doi.org/10.12688/f1000research.2-212.v1.

Full text
Abstract:
The B family of Eph receptor tyrosine kinases and their ephrin ligands, best known for their role in the development of the nervous and vascular systems, have recently been implicated in mammalian kidney development and maintenance. However, the renal expression and function of the EphA and ephrin-A families have not been investigated. We performed immunohistochemistry for ephrin-A2 and ephrin-A5 in kidneys of normal adult wildtype (WT) mice and carried out quantitative morphological analysis of renal corpuscles and tubules in haematoxylin- and eosin-stained sections of WT, ephrin-A2-/-, ephri
APA, Harvard, Vancouver, ISO, and other styles
10

Kamitori, Kazuyo, Mitsuru Machide, Noriko Osumi, and Shinichi Kohsaka. "Expression of receptor tyrosine kinase RYK in developing rat central nervous system." Developmental Brain Research 114, no. 1 (1999): 149–60. http://dx.doi.org/10.1016/s0165-3806(99)00033-4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Kidney; Nervous system; Tyrosine kinase"

1

Marcos-Gutierrez, Camelia Victoria. "Expression, function and conservation of the c-Ret proto-oncogene." Thesis, Open University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361457.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Coonan, Jason R. "Regulation of neural connectivity by the EphA4 receptor tyrosine kinase /." Connect to thesis, 2001. http://eprints.unimelb.edu.au/archive/00000727.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Robertson, Sears Heather C. 1975. "The receptor tyrosine phosphatase Ptp69D and the receptor tyrosine kinase Pvr in Drosophila nervous system development." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/32254.

Full text
Abstract:
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2004.<br>Includes bibliographical references.<br>Cell migration and axon guidance are highly similar processes important for the development of the nervous system. Both processes involve the transduction of signals across the membrane, resulting in changes in the cytoskeleton. I have examined the roles of two receptors that are involved in axon guidance and cell migration in Drosophila. Ptp69D is a receptor tyrosine phosphatase required for axon guidance in the developing embryo and for layer-specific axon targeting in t
APA, Harvard, Vancouver, ISO, and other styles
4

Soskis, Michael. "A Chemical-Genetic Study of EphB Receptor Tyrosine Kinase Signaling in the Developing Nervous System." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10525.

Full text
Abstract:
EphB receptor tyrosine kinases regulate cell-cell contacts throughout nervous system development, mediating processes as diverse as axon guidance, topographic mapping, neuronal migration and synapse formation. EphBs bind to a group of ligands, ephrin-Bs, which span the plasma membrane, thus allowing for bidirectional signaling between cells. Since EphBs are capable of multiple modes of signaling, and since they regulate numerous interdependent stages of development, it has been challenging to define which signaling functions of EphBs mediate particular developmental events. To overcome this hu
APA, Harvard, Vancouver, ISO, and other styles
5

Wallace, Adam Spencer. "The role of the receptor tyrosine kinase RET as a dependence receptor during enteric nervous system formation." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445143/.

Full text
Abstract:
Enteric neurons are derived from vagal and sacral neural crest cell populations. Using human embryonic tissue aged 4-14 weeks of gestation the timing and pattern of gastrointestinal colonisation by vagal neural crest cells, and the development of interstitial cells of Cajal and the smooth musculature of the gut, were investigated using immunohistochemistry. Formation of both the enteric nervous system and smooth muscle involves rostrocaudal migration and maturation of these tissues. The gut is fully colonised by neural crest cells at week 7 and these cells first form the myenteric plexus exter
APA, Harvard, Vancouver, ISO, and other styles
6

Eberhart, Johann. "EphA4/Ephrin interactions in motor axon guidance /." free to MU campus, to others for purchase, 2002. http://wwwlib.umi.com/cr/mo/fullcit?p3060095.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Vernersson, Lindahl Emma. "Investigating the function of Anaplastic Lymphoma Kinase." Doctoral thesis, Umeå : Univ, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1956.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Park, Minwoo. "2',3'-Cyclic nucleotide 3'-phosphodiesterase : investigation of interaction with Fyn tyrosine kinase during the development of nervous system, and mitochondrial import of CNP2 isoform." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81423.

Full text
Abstract:
2',3'-Cyclic nucleotide 3'-phosphodiesterase is a protein highly expressed in oligodendrocytes in the central nervous system, and it is believed to be an important regulator of myelination. In this report, two aspects of CNP are investigated, each introduced in their own chapters.<br>First, a possible interaction of CNP with Fyn tyrosine kinase during myelination is investigated. Fyn is an important factor known to be active during the process of myelination, and CNP contains a number of possible tyrosine phosphorylation sites. Furthermore, their presence in an isolated domain of cell m
APA, Harvard, Vancouver, ISO, and other styles
9

Abbott, Mary-Alice. "Structural and Signaling Proteins at the Synapse: Dystroglycan & Insulin Receptor Tyrosine Kinase Substrate p58/53: a Dissertation." eScholarship@UMMS, 1999. https://escholarship.umassmed.edu/gsbs_diss/124.

Full text
Abstract:
The synapse is the primary locus of cell-cell communication in the nervous system. The elaboration of a functional synapse requires both a specialized structure and an efficient communication system. For my thesis work, I studied proteins implicated in each of these functions: the structural molecules dystroglycan and dystrophin, and the signaling elements Insulin Receptor Substrate p58/53 and insulin receptor. The α/β-dystroglycan complex, believed to be the heart of cellmatrix adhesion in muscle and other tissues, provides a link between dystrophin, a cytoskeletal protein at the base of the
APA, Harvard, Vancouver, ISO, and other styles
10

Pins, Benoit de. "Pathophysiological role of Pyk2 in the nervous system Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related microstructural changes Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington’s disease model." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS073.

Full text
Abstract:
Proline-rich tyrosine kinase 2 (Pyk2) est une tyrosine kinase dépendante du calcium de la famille de focal adhésion kinase (FAK). Cette thèse rapporte l’étude Pyk2 dans des conditions neuropathologiques in vivo, en utilisant des délétions conditionnelles ou totales de Pyk2 chez la souris. La délétion de Pyk2 dans l’hippocampe provoque des altérations synaptiques associées à des défauts de LTP et d’apprentissage lié à l’hippocampe confirmant l’importance de Pyk2 dans l’expression de la plasticité synaptique. Les maladies de Huntington et d’Alzheimer sont associées à un déficit du niveau total o
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Kidney; Nervous system; Tyrosine kinase"

1

Vormoor, H. Josef, Tobias F. Menne, and Anthony V. Moorman. "Acute lymphoblastic leukaemia." In Oxford Textbook of Medicine, edited by Chris Hatton and Deborah Hay. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0523.

Full text
Abstract:
Acute lymphoblastic leukaemia (ALL) is a malignant proliferation of lymphoid blasts, most commonly of B-lineage origin. The clinical symptoms and signs are either a consequence of bone marrow failure (infections, bruising, petechiae, pallor, and tiredness) or a consequence of the uncontrolled proliferation of the blasts (lymphadenopathy, hepatosplenomegaly, and cranial nerve palsies). Its peak incidence is in young children but ALL occurs at all ages. More than 80% of all affected children are cured with modern chemotherapy, but unfortunately the outcome of adults is much worse despite some improvements led by the introduction of paediatric-inspired protocols and tyrosine kinase inhibitors in BCR-ABL1-positive ALL. Standard chemotherapy for ALL consists of several months of intensive multidrug induction, consolidation and intensification chemotherapy (including steroids, vincristine, asparaginase and anthracyclines), intrathecal methotrexate to target blasts in the central nervous system, and low-intensity maintenance therapy (with oral 6-mercaptopurine and methotrexate) for up to 3 years. Treatment is stratified according to the response and other prognostic biomarkers (including genetics). Allogeneic haematopoietic stem cell transplantation is used predominantly in the relapse setting for children but in frontline therapy for adult patients to consolidate chemotherapy. Novel targeted small molecules and, in particular, immunotherapy are promising to offer new treatment options for patients with high-risk or relapsed disease.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Kidney; Nervous system; Tyrosine kinase' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography