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Relevant bibliographies by topics / Kidney; Nervous system; Tyrosine kinase / Dissertations / Theses

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Dissertations / Theses on the topic 'Kidney; Nervous system; Tyrosine kinase'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Marcos-Gutierrez, Camelia Victoria. "Expression, function and conservation of the c-Ret proto-oncogene." Thesis, Open University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361457.

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2

Coonan, Jason R. "Regulation of neural connectivity by the EphA4 receptor tyrosine kinase /." Connect to thesis, 2001. http://eprints.unimelb.edu.au/archive/00000727.

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3

Robertson, Sears Heather C. 1975. "The receptor tyrosine phosphatase Ptp69D and the receptor tyrosine kinase Pvr in Drosophila nervous system development." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/32254.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2004.<br>Includes bibliographical references.<br>Cell migration and axon guidance are highly similar processes important for the development of the nervous system. Both processes involve the transduction of signals across the membrane, resulting in changes in the cytoskeleton. I have examined the roles of two receptors that are involved in axon guidance and cell migration in Drosophila. Ptp69D is a receptor tyrosine phosphatase required for axon guidance in the developing embryo and for layer-specific axon targeting in t

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4

Soskis, Michael. "A Chemical-Genetic Study of EphB Receptor Tyrosine Kinase Signaling in the Developing Nervous System." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10525.

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EphB receptor tyrosine kinases regulate cell-cell contacts throughout nervous system development, mediating processes as diverse as axon guidance, topographic mapping, neuronal migration and synapse formation. EphBs bind to a group of ligands, ephrin-Bs, which span the plasma membrane, thus allowing for bidirectional signaling between cells. Since EphBs are capable of multiple modes of signaling, and since they regulate numerous interdependent stages of development, it has been challenging to define which signaling functions of EphBs mediate particular developmental events. To overcome this hu

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5

Wallace, Adam Spencer. "The role of the receptor tyrosine kinase RET as a dependence receptor during enteric nervous system formation." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445143/.

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Enteric neurons are derived from vagal and sacral neural crest cell populations. Using human embryonic tissue aged 4-14 weeks of gestation the timing and pattern of gastrointestinal colonisation by vagal neural crest cells, and the development of interstitial cells of Cajal and the smooth musculature of the gut, were investigated using immunohistochemistry. Formation of both the enteric nervous system and smooth muscle involves rostrocaudal migration and maturation of these tissues. The gut is fully colonised by neural crest cells at week 7 and these cells first form the myenteric plexus exter

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6

Eberhart, Johann. "EphA4/Ephrin interactions in motor axon guidance /." free to MU campus, to others for purchase, 2002. http://wwwlib.umi.com/cr/mo/fullcit?p3060095.

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7

Vernersson, Lindahl Emma. "Investigating the function of Anaplastic Lymphoma Kinase." Doctoral thesis, Umeå : Univ, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1956.

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8

Park, Minwoo. "2',3'-Cyclic nucleotide 3'-phosphodiesterase : investigation of interaction with Fyn tyrosine kinase during the development of nervous system, and mitochondrial import of CNP2 isoform." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81423.

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2',3'-Cyclic nucleotide 3'-phosphodiesterase is a protein highly expressed in oligodendrocytes in the central nervous system, and it is believed to be an important regulator of myelination. In this report, two aspects of CNP are investigated, each introduced in their own chapters.<br>First, a possible interaction of CNP with Fyn tyrosine kinase during myelination is investigated. Fyn is an important factor known to be active during the process of myelination, and CNP contains a number of possible tyrosine phosphorylation sites. Furthermore, their presence in an isolated domain of cell m

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9

Abbott, Mary-Alice. "Structural and Signaling Proteins at the Synapse: Dystroglycan & Insulin Receptor Tyrosine Kinase Substrate p58/53: a Dissertation." eScholarship@UMMS, 1999. https://escholarship.umassmed.edu/gsbs_diss/124.

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The synapse is the primary locus of cell-cell communication in the nervous system. The elaboration of a functional synapse requires both a specialized structure and an efficient communication system. For my thesis work, I studied proteins implicated in each of these functions: the structural molecules dystroglycan and dystrophin, and the signaling elements Insulin Receptor Substrate p58/53 and insulin receptor. The α/β-dystroglycan complex, believed to be the heart of cellmatrix adhesion in muscle and other tissues, provides a link between dystrophin, a cytoskeletal protein at the base of the

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10

Pins, Benoit de. "Pathophysiological role of Pyk2 in the nervous system Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related microstructural changes Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington’s disease model." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS073.

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Proline-rich tyrosine kinase 2 (Pyk2) est une tyrosine kinase dépendante du calcium de la famille de focal adhésion kinase (FAK). Cette thèse rapporte l’étude Pyk2 dans des conditions neuropathologiques in vivo, en utilisant des délétions conditionnelles ou totales de Pyk2 chez la souris. La délétion de Pyk2 dans l’hippocampe provoque des altérations synaptiques associées à des défauts de LTP et d’apprentissage lié à l’hippocampe confirmant l’importance de Pyk2 dans l’expression de la plasticité synaptique. Les maladies de Huntington et d’Alzheimer sont associées à un déficit du niveau total o

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11

Yokota, Asumi. "INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph[+] leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity." Kyoto University, 2009. http://hdl.handle.net/2433/126449.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(医学)<br>甲第14902号<br>医博第3387号<br>新制||医||977(附属図書館)<br>27340<br>UT51-2009-M816<br>京都大学大学院医学研究科医学専攻<br>(主査)教授武藤誠, 教授武田俊一, 教授松岡雅雄, 教授戸井雅和<br>学位規則第4条第1項該当

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12

Guidi, Mònica. "Micro RNA-Mediated regulation of the full-length and truncated isoforms of human neurotrophic tyrosine kinase receptor type 3 (NTRK 3)." Doctoral thesis, Universitat Pompeu Fabra, 2009. http://hdl.handle.net/10803/7114.

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Neurotrophins and their receptors are key molecules in the development of the<br/>nervous system. Neurotrophin-3 binds preferentially to its high-affinity receptor<br/>NTRK3, which exists in two major isoforms in humans, the full-length kinaseactive<br/>form (150 kDa) and a truncated non-catalytic form (50 kDa). The two<br/>variants show different 3'UTR regions, indicating that they might be differentially<br/>regulated at the post-transcriptional level. In this work we explore how<br/>microRNAs take part in the regulation of full-length and truncated NTRK3,<br/>demonstrating that the two isof

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13

Chan, Onyee, Abdur Rehman Jamil, Rebecca Millius, Ramandeep Kaur, and Faiz Anwer. "Mixed phenotype acute leukemia with t(9;22): success with nonacute myeloid leukemia-type intensive induction therapy and stem cell transplantation." WILEY, 2017. http://hdl.handle.net/10150/624353.

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14

Britsch, Stefan. "Genetische Analyse entwicklungsbiologischer Funktionen des Neuregulin-1/ErbB Signalsystems." Doctoral thesis, [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973133449.

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15

Althini, Susanna. "Experimental Studies of BMP Signalling in Neuronal Cells." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3398.

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16

Cary, Daniele Catherine. "RON receptor tyrosine kinase expression is decreased during simian immunodeficiency virus associated central nervous system disease." Thesis, 2014. https://hdl.handle.net/2144/13165.

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The receptor tyrosine kinase, RON, is expressed on tissue-resident macrophages. RON functions by activating genes that promote wound repair and resolve inflammation, while repressing genes that perpetuate tissue damage and cell death. Chronic HIV infection is associated with dysregulated inflammation, and we hypothesize that diminished macrophage RON expression contributes to the development of end organ diseases including HIV-associated central nervous system (CNS) inflammation. We utilized CNS tissue from a SIV macaque model to examine the temporal regulation of RON in the brain during infe

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17

Hu, Tian-jing. "Regulation of process retraction and cell migration by Epha3 is mediated by the by the adaptor protein Nck1." 2007. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.16096.

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18

Cooper, Margaret Ann. "Novel developmental roles of EphA receptors." 2008. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.17454.

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19

Jammow, Wafaa J. "Récepteur EphA7 : expression régionale dans le cerveau et localisation ultrastructurale dans l’hippocampe chez le rat et la souris adultes." Thèse, 2012. http://hdl.handle.net/1866/8571.

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EphA7 est un membre de la famille des récepteurs à tyrosine kinase Eph, qui régulent l’adhérence et la motilité cellulaires. EphA7 est hautement conservé chez les vertébrés et largement exprimé durant l'embryogenèse, en particulier pendant le développement du SNC. Dans le cerveau adulte, EphA7 est transcrit principalement dans l'hippocampe, avec de faibles niveaux d'expression ailleurs. Nous avons cartographié sa distribution dans le cerveau du rat et de la souris adultes, par hybridation in situ et immunohistochimie en microscopie photonique et électronique. Les deux méthodes montrent une dis

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20

Bernard-Gauthier, Vadim. "Développement et radiosynthèse de ligands du récepteur tyrosine kinase neurotrophique type 2 (TrkB) marqués aux carbone-11 et fluor-18 pour l’imagerie cérébrale par tomographie d’émission de positons." Thèse, 2013. http://hdl.handle.net/1866/10664.

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Ce mémoire présente mes travaux ayant menés au développement d’une première génération de radioligands marqués au fluor-18 (t1/2 = 110 min) et au carbone-11 (t1/2 = 20.4 min) destinés à l’imagerie cérébrale in vivo du récepteur tyrosine kinase neurotrophique de type 2 (TrkB) en tomographie par émission de positons (TEP). Ces travaux reposent sur l’identification récente de ligands de TrkB non peptidiques à hautes affinités dérivés du 7,8-dihydroxyflavone. La synthèse d’une série de dérivés du 7,8-dihydroxyflavone non-radioactifs de même que des précuseurs à l’incorporation du fluro-18 et du c

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21

VanDusen, Nathan J. "Hand2 function within non-cardiomyocytes regulates cardiac morphogenesis and performance." Thesis, 2014. http://hdl.handle.net/1805/6170.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>The heart is a complex organ that is composed of numerous cell types, which must integrate their programs for proper specification, differentiation, and cardiac morphogenesis. During cardiac development the basic helix-loop-helix transcription factor Hand2 is dynamically expressed within the endocardium and extra-cardiac lineages such as the epicardium, cardiac neural crest cells (cNCCs), and NCC derived components of the autonomic nervous system. To investigate Hand2 function within these populations we utilized multiple murine Hand

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