Academic literature on the topic 'Kidney recipient'

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Journal articles on the topic "Kidney recipient"

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Churchill, P. C., M. C. Churchill, and A. K. Bidani. "Kidney cross transplants in Dahl salt-sensitive and salt-resistant rats." American Journal of Physiology-Heart and Circulatory Physiology 262, no. 6 (1992): H1809—H1817. http://dx.doi.org/10.1152/ajpheart.1992.262.6.h1809.

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Previous kidney cross-transplant studies have demonstrated that the genotype of the kidney plays a role in determining the blood pressure of the recipient in Dahl salt-sensitive (S) and salt-resistant (R) rats. The present studies were designed to elucidate this role. Kidney cross transplants were performed in unilaterally nephrectomized male recipients (John Rapp strains), such that each rat had a native kidney and a transplanted kidney of the opposite genotype. S and R rats with a native kidney and a transplanted kidney of the same genotype served as controls. After 4 wk on a 7.8% NaCl diet, rats were anesthetized and renal clearance studies were performed. S kidneys had lower glomerular filtration rate (GFR) and renal plasma flow (RPF) than R kidneys, and these differences were determined by the kidney's genotype rather than the recipient's, since S kidneys in R recipients tended to have lower GFR and RPF than R kidneys in S recipients. In contrast, independent of the kidney's genotype, the kidneys in S rats tended to have higher fractional excretion of H2O and Na (FEH2O and FENa) than the kidneys in R rats. Thus there were genetically determined differences in renal function between S and R rats; some (RPF and GFR) were intrinsic to the kidney, whereas others (FEH2O and FENa) were intrinsic to the host.(ABSTRACT TRUNCATED AT 250 WORDS)
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Ismail, Omar Mobeen, Mahmud Saedon, Videha Sharma, Argiris Asderakis, and Titus Augustine. "Staggered Dual Kidney Transplantation." Progress in Transplantation 31, no. 3 (2021): 263–66. http://dx.doi.org/10.1177/15269248211024606.

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We describe a case where a patient received a successful dual kidney transplantation in a staggered fashion. Two kidneys from a deceased donor were accepted for 2 separate primary intended recipients, however, due to unforeseen circumstances, both kidneys were eventually transplanted in a staggered fashion into an alternate single recipient. The intention behind this method was to enhance the patient’s renal function and to prevent the wastage of a kidney. Despite the significantly prolonged cold ischemia times, the recipient has excellent dual graft function after 3 years. The positive outcome underpins the effectiveness of donor kidneys even with prolonged cold ischemia times outside established best practice guidelines. It also reinforces the effectiveness of dual kidney transplantation. Transplant professionals encounter complex situations occasionally where an established evidence-base or aids to decision-making are limited. This case reflects challenges in decision-making, patient counselling and consent, especially when the opportunity for the staggered dual kidney transplantation, with potential increased morbidity, came about as another recipient declined a usable kidney. It also highlights the widely differing risk appetites of different patients. Crucially, it optimised the donation process and procurement of 2 kidneys while preventing wastage. To our knowledge, this is the first report of a staggered dual kidney transplantation in a single recipient.
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Potluri, Vishnu S., David S. Goldberg, Sumit Mohan, et al. "National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys." Journal of the American Society of Nephrology 30, no. 10 (2019): 1939–51. http://dx.doi.org/10.1681/asn.2019050462.

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BackgroundRecent pilot trials have demonstrated the safety of transplanting HCV-viremic kidneys into HCV-seronegative recipients. However, it remains unclear if allograft function is impacted by donor HCV-viremia or recipient HCV-serostatus.MethodsWe used national United States registry data to examine trends in HCV-viremic kidney use between 4/1/2015 and 3/31/2019. We applied advanced matching methods to compare eGFR for similar kidneys transplanted into highly similar recipients of kidney transplants.ResultsOver time, HCV-seronegative recipients received a rising proportion of HCV-viremic kidneys. During the first quarter of 2019, 200 HCV-viremic kidneys were transplanted into HCV-seronegative recipients, versus 69 into HCV-seropositive recipients, while 105 HCV-viremic kidneys were discarded. The probability of HCV-viremic kidney discard has declined over time. Kidney transplant candidates willing to accept a HCV-seropositive kidney increased from 2936 to 16,809 from during this time period. When transplanted into HCV-seronegative recipients, HCV-viremic kidneys matched to HCV-non-viremic kidneys on predictors of organ quality, except HCV, had similar 1-year eGFR (66.3 versus 67.1 ml/min per 1.73 m2, P=0.86). This was despite the much worse kidney donor profile index scores assigned to the HCV-viremic kidneys. Recipient HCV-serostatus was not associated with a clinically meaningful difference in 1-year eGFR (66.5 versus 71.1 ml/min per 1.73 m2, P=0.056) after transplantation of HCV-viremic kidneys.ConclusionsBy 2019, HCV-seronegative patients received the majority of kidneys transplanted from HCV-viremic donors. Widely used organ quality scores underestimated the quality of HCV-viremic kidneys based on 1-year allograft function. Recipient HCV-serostatus was also not associated with worse short-term allograft function using HCV-viremic kidneys.
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Bullen, Alexander, and Mita M. Shah. "De Novo Postinfectious Glomerulonephritis Secondary to Nephritogenic Streptococci as the Cause of Transplant Acute Kidney Injury: A Case Report and Review of the Literature." Case Reports in Transplantation 2018 (May 31, 2018): 1–5. http://dx.doi.org/10.1155/2018/2695178.

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Acute kidney injury is common among kidney transplant recipients. Postinfectious glomerulonephritis secondary to nephritogenic streptococci is one of the oldest known etiologies of acute kidney injury in native kidneys but rarely reported among kidney transplant recipients. This report is of a biopsy-proven case of acute kidney injury in a renal allograft recipient caused by de novo poststreptococcal glomerulonephritis.
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Lepeytre, Fanny, Catherine Delmas-Frenette, Xun Zhang, et al. "Donor Age, Donor-Recipient Size Mismatch, and Kidney Graft Survival." Clinical Journal of the American Society of Nephrology 15, no. 10 (2020): 1455–63. http://dx.doi.org/10.2215/cjn.02310220.

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Background and objectivesSmall donor and/or kidney sizes relative to recipient size are associated with a higher risk of kidney allograft failure. Donor and recipient ages are associated with graft survival and may modulate the relationship between size mismatch and the latter. The aim of this study was to determine whether the association between donor-recipient size mismatch and graft survival differs by donor and recipient age.Design, setting, participants, & measurementWe performed a retrospective cohort study of first adult deceased donor kidney transplantations performed between 2000 and 2018 recorded in the Scientific Registry of Transplant Recipients. We used multivariable Cox proportional hazards models to assess the association between donor-recipient body surface area ratio and death-censored graft survival, defined as return to dialysis or retransplantation. We considered interactions between donor-recipient body surface area ratio and each of recipient and donor age.ResultsAmong the 136,321 kidney transplant recipients included in this study, 23,614 (17%) experienced death-censored graft loss over a median follow-up of 4.3 years (interquartile range, 1.9–7.8 years). The three-way donor-recipient body surface area ratio by donor age by recipient age interaction was statistically significant (P=0.04). The magnitude of the association between severe size mismatch (donor-recipient body surface area ratio <0.80 versus ≥1.00) and death-censored graft survival was stronger with older donor age and recipient age. In all recipient age categories except the youngest (18–30 years), 5- and 10-year graft survival rates were similar or better with a size-mismatched donor aged <40 years than a nonsize-mismatched donor aged 40 years or older.ConclusionsThe association of donor-recipient size mismatch on long-term graft survival is modulated by recipient and donor age. Size-mismatched kidneys yield excellent graft survival when the donor is young. Donor age was more strongly associated with graft survival than size mismatch.
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LIU, SHANYING, JENS LUTZ, BALAZS ANTUS, et al. "Recipient Age and Weight Affect Chronic Renal Allograft Rejection in Rats." Journal of the American Society of Nephrology 12, no. 8 (2001): 1742–49. http://dx.doi.org/10.1681/asn.v1281742.

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Abstract. Nephron doses and immune responses change with age. Therefore, age is a potential risk factor for graft survival after kidney transplantation. The aim of this study was to determine whether age-related differences are of importance for long-term outcomes after renal transplantation. Kidneys from Fisher 344 rats were orthotopically transplanted into nephrectomized Lewis rats. Kidneys were transplanted using donors and recipients of three age levels,i.e., young (8 wk of age), adult (16 wk of age), and old (40 wk of age). Rats were killed 24 wk after transplantation, and functional, morphologic, and molecular evaluations were performed. Recipient age, rather than donor age, determined graft survival rates. No significant correlation was observed between donor kidney weight on the day of transplantation and morphologic results. Advanced recipient age was associated with reduced creatinine clearance, more severe histologic injuries, including extended glomerular sclerosis, interstitial fibrosis, and vascular lesions, more pronounced cellular infiltration, and greater expression of transforming growth factor-β and platelet-derived growth factor A and B chains. Although no significant correlation between donor age or kidney weight on the day of transplantation and morphologic results was observed, there was a significant correlation between recipient body weight on the day of transplantation and allograft injury. It is concluded that recipient age and weight affect chronic renal rejection. Renal allografts may benefit from young recipient age but may deteriorate in old recipients, suggesting effects of recipient functional demand on long-term outcomes.
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Torreggiani, Massimo, Ciro Esposito, Elena Martinelli, et al. "Outcomes in Living Donor Kidney Transplantation: The Role of Donor’s Kidney Function." Kidney and Blood Pressure Research 46, no. 1 (2021): 84–94. http://dx.doi.org/10.1159/000512177.

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Introduction: Living donor kidney transplant (LDKT) is one of the best therapeutic options for end-stage kidney disease (ESKD). Guidelines identify different estimated glomerular filtration rate (eGFR) thresholds to determine the eligibility of donors. The aim of our study was to evaluate whether pretransplant donor eGFR was associated with kidney function in the recipient. Methods: We retrospectively studied LDKT recipients who received a kidney graft between September 1, 2005, and June 30, 2016 in the same transplant center in France and that had eGFR data available at 3, 12, 24, and 36 months posttransplant. Results: We studied 90 donor-recipient pairs. The average age at time of transplant was 51.47 ± 10.95 for donors and 43.04 ± 13.52 years for recipients. Donors’ average eGFR was 91.99 ± 15.37 mL/min/1.73 m2. Donor’s age and eGFR were significantly correlated (p < 0.0001, r2 0.023). Donor’s age and eGFR significantly correlated with recipient’s eGFR at 3, 12, and 24 months posttransplant (age: p < 0.001 at all intervals; eGFR p = 0.001, 0.003, and 0.016, respectively); at 36 months, only donor’s age significantly correlated with recipient’s eGFR. BMI, gender match, and year of kidney transplant did not correlate with graft function. In the multivariable analyses, donor’s eGFR and donor’s age were found to be associated with graft function; correlation with eGFR was lost at 36 months; and donor’s age retained a strong correlation with graft function at all intervals (p < 0.001). Conclusions: Donor’s eGFR and age are strong predictors of recipient’s kidney function at 3 years. We suggest that donor’s eGFR should be clinically balanced with other determinants of kidney function and in particular with age.
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Mohammed, Hussein Jassim. "Family caregiver's support for Jordanian kidney transplantation recipient." New Trends and Issues Proceedings on Humanities and Social Sciences 4, no. 2 (2017): 161–69. http://dx.doi.org/10.18844/prosoc.v4i2.2478.

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Ebad, Chaudhry Adeel, David Brennan, Julio Chevarria, et al. "Is Bigger Better? Living Donor Kidney Volume as Measured by the Donor CT Angiogram in Predicting Donor and Recipient eGFR after Living Donor Kidney Transplantation." Journal of Transplantation 2021 (July 9, 2021): 1–6. http://dx.doi.org/10.1155/2021/8885354.

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Background. The role of kidney volume measurement in predicting the donor and recipient kidney function is not clear. Methods. We measured kidney volume bilaterally in living kidney donors using CT angiography and assessed the association with the donor remaining kidney and recipient kidney (donated kidney) function at 1 year after kidney transplantation. Donor volume was categorized into tertiles based on lowest, middle, and highest volume. Results. There were 166 living donor and recipient pairs. The mean donor age was 44.8 years (SD ± 10.8), and donor mean BMI was 25.5 (SD ± 2.9). The recipients of living donor kidneys were 64% male and had a mean age of 43.5 years (SD ± 13.3). Six percent of patients experienced an episode of cellular rejection and were maintained on dialysis for a mean of 18 months (13–32) prior to transplant. Kidney volume was divided into tertiles based on lowest, middle, and highest volume. Kidney volume median (range) in tertiles 1, 2, and 3 was 124 (89–135 ml), 155 (136–164 ml), and 184 (165–240 ml) with donor eGFR ml/min (adjusted for body surface area expressed as ml/min/1.73 m2) at the time of donation in each tertile, 109 (93–129), 110 (92–132), and 101 ml/min (84–117). The median (IQR) eGFR in tertiles 1 to 3 in kidney recipients at 1 year after donation was 54 (44–67), 62 (50–75), and 63 ml/min (58–79), respectively. The median (IQR) eGFR in tertiles 1 to 3 in the remaining kidney of donors at 1 year after donation was 59 (53–66), 65 (57–72), and 65 ml/min (56–73), respectively. Conclusion. Bigger kidney volume was associated with better eGFR at 1 year after transplant in the recipient and marginally in the donor remaining kidney.
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Mathes, David, Scott Stoll Graves, George E. Georges, et al. "Long-Term Tolerance to Kidney Allografts After Induced Rejection of Donor Hematopoietic Chimerism in a Preclinical Canine Model." Blood 120, no. 21 (2012): 2991. http://dx.doi.org/10.1182/blood.v120.21.2991.2991.

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Abstract Abstract 2991 Allogeneic hematopoietic cell transplantation provides a reliable method for inducing tolerance towards solid organ grafts. However, this procedure can result in graft-versus-host disease (GVHD) thereby limiting its application. Here we test the hypothesis that mixed chimerism can be intentionally reverted to host hematopoiesis without rejection of a kidney graft. Recipient dogs were given 2 Gy total body irradiation (TBI) before and a short course of immunosuppression after marrow infusion from dog leukocyte antigen-identical littermates. All dogs achieved stable mixed chimerism. After a mean of 20 weeks, one cohort of dogs received kidney transplants from their respective marrow donors. Subsequently, recipients were reconditioned with 2 Gy TBI and given autologous granulocyte-colony stimulating factor-mobilized leukocytes (recipient leukocyte infusion) that had been collected before marrow transplant. Dogs receiving a second TBI and recipient leukocyte infusion without a kidney transplant rejected their donor hematopoietic graft within 3 weeks. Dogs that received kidney grafts, followed by a second TBI and recipient leukocyte infusion, rejected their marrow graft without rejecting their transplanted kidneys for periods greater than one year. Mixed chimerism may be clinically reverted to 100% recipient without rejection of a kidney allograft. This model has potential applications in understanding the mechanism of split tolerance. This finding may have application towards minimizing the risk of GVHD in solid organ transplant patients given hematopoietic cell transplantation from HLA-identical donors. Disclosures: No relevant conflicts of interest to declare.
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Dissertations / Theses on the topic "Kidney recipient"

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O'Dair, Jonathan David. "Kidney transplant : graft and recipient profiling." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/10877/.

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Despite the recent introduction of a number of new and more potent anti-rejection drugs, the incidence of rejection and long-term graft survival remain unchanged. There remains a significant difference in long-term graft survival depending on the source of the donor. The purpose of this study was to examine gene expression in the transplanted kidney using microarray technology to identify potential biomarkers that could be used to predict and monitor graft function so that appropriate interventions could be made in the event of graft dysfunction. Over a 5 year period RNA was extracted from 144 donor kidneys that were transplanted. The initial attempts at probe preparation and hybridization were unsuccessful. This led to the development of a new strategy which involved the use of state-of-the-art microarray technology which embraced the advances realised with the completion of the human genome project. Microarray data was analysed using J-Express and Pathway studio. Significance analysis of microarray, hierachical clustering, gene ontology mapping and pathway analysis was performed. The identification of potential biomarkers that had previously been described by other authors validated this approach. In addition novel genes were identified that may have a role as biomarkers of graft function. Other potential biomarkers were identified that represented cellular processes that could be modified by therapeutic intervention thus possibly changing the clinical outcome or allowing monitoring of the success of therapy. Confirmation of previously described biomarkers and the identification of novel potential biomarkers has confirmed that gene expression profiling has a valuable role in identifying processes that are indicative of disease processes including those involved in kidney transplantation. Furthermore with the development of minimally invasive tests to measure these biomarkers, we can potentially change the natural history of the disease process, and hence, preserve graft function and possibly prolong life.
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Ruttledge, Sylvia. "Information provision and kidney donor and recipient decision making." Thesis, University of Leeds, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540765.

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Gill, Paul. "Illuminating donor and recipient experiences in live kidney transplantation." Thesis, Cardiff University, 2006. http://orca.cf.ac.uk/54297/.

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Live kidney transplants are a successful and efficient means of treating those with chronic renal failure. However, the procedure is associated with potential physical and psychosocial risks, such as operative complications and pressure to donate and receive. Recipients also often feel grateful, even 'indebted', to the donors and, consequently, this can affect their relationship with each other. Despite these issues, few studies have focused on the experiences of those involved in live transplantation. This study was, therefore, undertaken to provide an in-depth insight into this process from the participants' perspectives. Therefore, the aims of this qualitative, longitudinal study were to explore: > The experiences of donors and recipients throughout the live transplantation process > The relevance of the anthropological theory of 'gift exchange' as a framework for exploring and understanding the live kidney transplantation process > How a theoretically informed insight into these experiences may be used to inform and develop future research and clinical practice A qualitative, phenomenological approach was used to explore the experiences of 11 live kidney donors and their recipients in South-West England. Data were collected through a series of three semi-structured interviews, conducted pre- transplant and at three and ten months post-transplant. Interviews were transcribed verbatim and data coded into categories arising from participants' accounts. These findings were also considered within a theoretical framework of gift exchange. Live transplantation was the treatment of choice for all participants, especially recipients. All donors initially made an instantaneous, voluntary decision to donate and found the decision relatively easy to make. In contrast, recipients found accepting the donors' offer emotionally burdensome because of concern for their wellbeing. They were only really able to accept the transplant after discussing the matter with their donor and establishing that it was something that they really wanted to do. Recipients' lives were transformed by a successful transplant and they were subsequently very grateful to the donors for donating. Donors derived immense personal satisfaction from this outcome and it helped to confirm to them that what they had done had been worthwhile. However, the transplant rejected in one recipient and the effects of this failure were devastating. The provision of transplant services throughout this process were generally positively evaluated by participants, although several recommendations were suggested. Data from this study show that the experiences of participants interviewed, closely resembled the fundamental dynamics of the gift exchange process, thus supporting the hypothesis that this theory provides an appropriate framework for understanding the live transplantation process in these participants. The findings from this study have implications for clinical practice and future research in this area.
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Yellanki, Sampath Kumar. "Kidney Compatibility Score Generation for a Donor - Recipient pair using Fuzzy Logic." University of Toledo / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1345153510.

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Mastrocinque, Morgan M. "Epitope-based Re-matching of Donor-Recipient Pairs for Kidney Graft Allocation." Bowling Green State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu16171080745974.

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Nemati, Mohammadreza. "Machine Learning Approaches in Kidney Transplantation Survival Analysis using Multiple Feature Representations of Donor and Recipient." University of Toledo / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1596756241492039.

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Crow, Leah. "Impact of Body Mass Index on Medicare Payments in Renal Transplant Recipients." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1399276000.

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Hansson, Cecilia, and Selma Zilic. "Njurmottagares erfarenheter av livet efter en transplantation : En litteraturstudie i omvårdnad." Thesis, Malmö universitet, Fakulteten för hälsa och samhälle (HS), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-39627.

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Bakgrund: Mer än 10% av den västerländska befolkningen lever med kronisk njursvikt. Njurtransplantation är det effektivaste behandlingsalternativet vid svår kronisk njursvikt, och fler än 600 personer står på väntelistan för en ny njure i Sverige. Det är som sjuksköterska viktigt att se patienterna bakom sjukdomen och ha förståelse för deras individuella behov. Genom att få en uppfattning av patienternas livsvärld, har sjuksköterskan möjlighet att främja njurmottagarnas liv efter transplantationen. Syfte: Syftet med litteraturstudien var att belysa njurmottagares erfarenheter av livet efter en transplantation. Metod: En litteraturstudie baserad på 10 vetenskapliga studier med kvalitativ ansats. Studiernas kvalitet granskades med hjälp av SBU:s granskningsmall och analyserades med en innehållsanalys. Resultat: Resultatet presenterades i tre tema och nio undertema. De tema som framkom var: Utmaningar i det dagliga livet, Livsförändringar och Självständighet. Slutsats: Njurmottagarna upplevde många olika känslor efter transplantationen. De kände glädje och tacksamhet, för att de hade fått en ny chans i livet, men också för att de inte längre var beroende av dialysbehandling. De upplevde också känslor av rädsla och oro, som var associerade till risken för njuravstötning och fysiska komplikationer. Dessutom hade anhöriga höga förväntningar som mottagarna inte kunde leva upp till, vilket bidrog till känslor av besvikelse. Genom personcentrerad vård och mycket information från sjuksköterskor, var njurmottagarna mer redo för livet efter transplantationen.<br>Background: More than 10% of the western population are living with kidney failure. The most effective treatment for severe chronic kidney failure is a kidney transplant, and more than 600 people are waiting for a new kidney in Sweden. It is important as a nurse to see the patient behind the disease and have understanding for their individual needs. By gaining insight of the person’s life-world, can the nurse promote kidney recipients life after a transplant. Aim: The purpose was to explore kidney recipient’s experiences of life after a transplantation. Method: A literature review based on 10 scientific articles with qualitative approach. The quality of the articles was reviewed and analyzed by a content analysis. Results: The results were presented in three themes and nine sub-themes. The themes presented were Challenges in the daily life, Life changes and Independence. Conclusion: The kidney recipients experienced different emotions after the transplant. They felt joy and gratitude, because they had been given a new chance in life, but also because they were no longer dependent on dialysis treatment. They also experienced feelings of fear and anxiety, which were associated with the risk of kidney rejection and physical complications. In addition, relatives had high expectations that the recipients could not live up to, which contributed to feelings of disappointment. The obstacles that the recipients experienced in life after the transplant, could the nurse support them in. Through person centered care and a lot of information from the nurses, were the kidney recipients more ready for life after the transplant.
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Rigatto, Claudio. "Cardiac disease in renal transplant recipients /." St. John's, NF : [s.n.], 2001.

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McGregor, Lesley M. "An investigation into the functional and psychosocial impact of living organ donation." Thesis, University of Stirling, 2010. http://hdl.handle.net/1893/2338.

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General Abstract Objective: In April 2006, the Scottish Liver Transplant Unit (SLTU) became the first NHS transplant unit in the UK to offer the option of Living Donor Liver Transplantation (LDLT). This represented a unique opportunity to evaluate the functional and psychosocial impact of LDLT upon healthy donors and their recipients. Subsequent aims were to investigate the challenge of introducing LDLT in Scotland and to establish the perceived deterrents and attractions of the procedure. An additional aim was to evaluate the impact of Living Donor Kidney Transplantation (LDKT) upon donors and recipients. Design: A series of cross sectional and longitudinal studies were designed for the purpose of this thesis (3 quantitative, 2 qualitative, and 1 mixed methods). Method: Self report questionnaires were used in each of the quantitative studies, with the addition of neuropsychological computerized tests in two studies. Semi-structured interviews were employed in the qualitative studies. Main Findings: •Prior to its introduction general support for the option of LDLT was found, although it was highlighted that the risk involved was not well understood by the general public. •Since becoming available LDLT has not been a readily acceptable treatment option from the perspective of patients due to the perceived risk for the donor, but it may be considered as a “last option”. Family members were motivated to save their loved one’s life but the personal implications of donating resulted in reconsideration of LDLT. • Staff at the SLTU perceived a lack of family commitment in relation to LDLT, which is explained as a cultural factor contributing to the slow uptake of LDLT. In Scotland, a donation from a younger to an older generation is not easily accepted. This, in addition to patients’ optimism that a deceased donation will arrive, and the poor health of potential donors, is thought to have affected the uptake of LDLT. As has the unit’s conservative approach to the promotion of LDLT. This approach is the result of a perceived reduction in the need for LDLT and a preference to avoid the risk to a healthy donor and conduct transplants with deceased donations. • In over 3 years, only one couple completed LDLT. The recipient showed functional and psychosocial improvement from pre to post procedure, whilst the donor showed slight deterioration in aspects of quality of life 6 weeks post donation, which did not always completely return to a baseline level by 6 months. The donor made sacrifices to provide her husband with a fresh start to life and unmet expectations were found to effect quality of life. •Willingness to become a liver donor is not thought to be influenced by the frame of the information provided. •Like the LDLT donor, LDKT donors experience some functional and psychosocial deterioration at 6 weeks post donation, but donors largely recover by 6 months post donation. However, the anticipated benefit to recipients was not evident and may not be quantifiable until after 6 months post operation. Conclusion: This thesis has added to current knowledge on living organ donation and specifically represents the first psychological evaluation of a UK LDLT programme. The slow uptake of LDLT was unexpected and has resulted in informative, novel research.
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Books on the topic "Kidney recipient"

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Chekesha. Fine thyme!: Vegetarian recipes from a kidney transplant recipient. Few Books, 2002.

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Lee, Linda Shin. Body size mismatch between donor and recipient in cadaveric kidney transplantation. s.n.], 1998.

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Kidney transplantation: A guide to the care of kidney transplant recipients. Springer, 2010.

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McKay, Dianne B., and Steven M. Steinberg, eds. Kidney Transplantation: A Guide to the Care of Kidney Transplant Recipients. Springer US, 2010. http://dx.doi.org/10.1007/978-1-4419-1690-7.

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Noorani, Hussein Zafer. Criteria for selection of adult recipients for heart, cadaveric kidney, and liver transplantation. Canadian Coordinating Office for Health Technology Assessment, 1999.

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Nessralla, Laurie-Ann. Incidence of rejection, morbidity, mortality and graft function in renal transplant recipients following cyclosporine to azathioprine switch. s.n.], 1990.

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Sherman, Michael Scott. Morbidity, mortality, and graft function in renal transplant recipients: A comparison of the effects of cyclosporine versus azathioprine. s.n.], 1986.

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Jong-Tieben, Linda M. de. Human papillomavirus infection and skin cancer in renal transplant recipients. University of Leiden, 1998.

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Allen, Richard D. M., and Henry C. C. Pleass. Donor and recipient kidney transplantation surgery. Edited by Jeremy R. Chapman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0278_update_001.

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Kidney transplant surgery is for thinking surgeons who enjoy being part of a multidisciplinary transplant team. Good ones recognize the small margin for error and avoid difficulties by careful preparation and anticipation of potential pitfalls. Progressively, their role has gained in significance and is now the most important variable in kidney graft loss in the first 6 months after transplantation. Deceased organ donation is complex, expensive, and insufficient in numbers to meet the demand for kidney transplantation. Living donor surgery is therefore a procedure of necessity. Laparoscopic approaches have obvious benefits to the patient but are not operations for the beginner. There are few remaining stalwarts of the open nephrectomy procedure. Because of the limited length of the donor ureter, kidney transplant procedures involve placement of the donor kidney into a heterotopic position with vascular anastomoses to the iliac vessels. No two procedures are the same. Observation of the transplanted kidney changing from a flaccid and pale appearance to one that is firm and pink, and within seconds of removing vascular clamps, is an unforgettable experience for the first timer. Even better is the sight of urine, minutes later. Good transplant centres select their new surgeons carefully!
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Aina, Titilopemi A. O., and Miguel Prada. Kidney Transplantation. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0024.

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Patients with end-stage renal disease (ESRD) can be managed with kidney transplantation, hemodialysis, or peritoneal dialysis. The most common organ transplanted in the United States is the kidney. Kidney transplantation surgery can be divided into the following stages: incision/dissection of vessels, cross-clamping vessels, vascular anastomosis, unclamping of vessels, ureter anastomosis to bladder, and closing. The size of recipient and donor kidneys as well as the size of recipient blood vessels will determine the position of graft implantation—either intraperitoneal or extraperitoneal. At the conclusion of surgery, most of the patients are extubated. This chapter describes the key steps in the preoperative assessment, explains the features of intraoperative anesthetic management, reviews the risk factors for reintubation, and identifies the optimal plan for postoperative pain management.
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Book chapters on the topic "Kidney recipient"

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Khankin, Eliyahu V., and Didier A. Mandelbrot. "Recipient Evaluation." In Kidney Transplantation. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0342-9_3.

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Doria, Cataldo, and Lauren Margetich. "Recipient Kidney Transplantation Surgery." In Contemporary Kidney Transplantation. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-19617-6_6.

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Doria, Cataldo, and Lauren Margetich. "Recipient Kidney Transplantation Surgery." In Contemporary Kidney Transplantation. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-14779-6_6-1.

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Shoskes, Daniel A. "Kidney Transplant Recipient Surgery." In Kidney and Pancreas Transplantation. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-642-9_10.

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Karhadkar, Sunil S., and David B. Leeser. "Surgical Issues in the Transplant Recipient." In Kidney Transplantation. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0342-9_11.

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Wadei, Hani M., and Stephen C. Textor. "Hypertension in the Kidney Transplant Recipient." In Kidney Transplantation. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0342-9_20.

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Manning, Maria, and Jade Wong-You-Cheong. "Imaging of the Renal Transplant Recipient." In Kidney Transplantation. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0342-9_32.

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Kazi, Saifullah N., Debbie Valsan, Robert Schoepe, and Keith Superdock. "Recipient Selection for Kidney Transplantation." In Contemporary Kidney Transplantation. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-19617-6_2.

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Kazi, Saifullah N., Debbie Valsan, Robert Schoepe, and Keith Superdock. "Recipient Selection for Kidney Transplantation." In Contemporary Kidney Transplantation. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-14779-6_2-1.

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Ashoor, Isa F., and Sonia Solomon. "Post-transplant Recipient Infectious Challenges." In Challenges in Pediatric Kidney Transplantation. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74783-1_5.

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Conference papers on the topic "Kidney recipient"

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Olson, M. T., A. Omar, R. Tenorio, H. Mohamed, and A. Arjuna. "Ibuprofen-induced Acute Kidney Injury in a Lung Transplant Recipient: A Case Report." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2351.

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Abu El-Sameed, Yaser, and Adhba Al Mubarak. "A 38-Year-Old Kidney Transplant Recipient With Productive Cough And Deteriorating Mental Status." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4717.

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Freeman, L., V. Hornsey, D. S. Pepper, P. R. Foster, L. Winkelman, and J. Dawes. "PROTEIN AGGREGATES IN HEATED BLOOD PRODUCTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644019.

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Heating of blood products to reduce viral infectivity is now a standard practice. Such treatment may also modify the constituent proteins, reducing their activity or altering their structure with potentially harmful consequences for the recipient. Partially denatured proteins frequently form aggregates, which are often immunogenic and could precipitate immune complex formation, allergic reactions and kidney damage. In addition they may contribute to the development of AIDS after HIV infection by inducing a persistent state of T-cell activation.Protein aggregate formation in factor VIII and factor IX (II + X) concentrates has been investigated by fast protein liquid chromatography (FPLC), which proved to be a rapid, convenient method for this purpose. Freeze-drying alone resulted in aggregate formation in intermediate purity FVIII concentrates, but not in FIX concentrates. However, aggregates were detected after heating the FIX concentrate at 80°C for 72h in the dry state. Dry heating of intermediate purity FVIII concentrates to 68°C for 24h also increased the content of protein aggregates, which contained fibrinogen and fibronectin but little IgG. In this product, the aggregate content after heating correlated with total protein concentration. A higher purity FVIII concentrate selectively depleted in fibrinogen and fibronectin also contained protein aggregates after freeze-drying, but heating this product at 80°C for 72h resulted in a relatively small increase in aggregate content. Haemophiliacs receiving regular injections of heated concentrates are constantly exposed to protein aggregates. They should be monitored for any harmful effects, and manufacturers should aim to reduce the aggregate content of their products.
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Godeau, Elise, Christian Caillard, Gregoire Jolly, et al. "Diagnostic Value of Flexible Bronchoscopy in kidney transplant recipients." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa4786.

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Schuurmans, Macé M., Gabrielo M. Tini, Christian Benden, Markus K. Mueller, Thomas Fehr, and Annette Boehler. "Kidney transplantation Improves Lung Function In Lung Transplant Recipients." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4326.

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Carvalho, Erich V., Edimar P. Gomes, Maycon M. Reboredo, et al. "Daily Life Physical Activities And Pulmonary Function In Kidney Transplant Recipients." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3105.

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Doddoli, S., P. Lafforgue, and T. Pham. "FRI0575 Safety of denosumab in a monocentric cohort of kidney transplant recipients." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.6899.

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Chiavegato, Luciana, Fernanda R. Santana, Rosimeire S. Padula, and Erika A. B. Suster. "Fatigue and functional capacity in kidney transplant recipients before and after transplant." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2524.

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Lin, Xiaohong, Yabin Shang, Sha Teng, Hongxia Liu, and Liu Han. "Relationship between perceived Social Support and Quality of Life among Kidney Transplant Recipients." In Annual Global Healthcare Conference. Global Science & Technology Forum (GSTF), 2015. http://dx.doi.org/10.5176/2251-3833_ghc15.20.

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Pan, Qiao, Xinyu Li, and Kun Shao. "Postoperative MPA-AUC Prediction for Kidney Transplant Recipients Based on Model Interpretability Technique." In BDE 2021: The 2021 3rd International Conference on Big Data Engineering. ACM, 2021. http://dx.doi.org/10.1145/3468920.3468937.

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Reports on the topic "Kidney recipient"

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Filipov, Jean, Tania Metodieva, Nikolay Hubanov, Emil Dimitiro, and Dobrin Svinarov. Cholecalciferol Supplementation and Its Effect on Proteinuria in Bulgarian Kidney Transplant Recipients. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2021. http://dx.doi.org/10.7546/crabs.2021.06.15.

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