Academic literature on the topic 'Kidneys Kidneys Cancer'

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Journal articles on the topic "Kidneys Kidneys Cancer"

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Hasumi, Hisashi, Masaya Baba, Yukiko Hasumi, et al. "Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn." Proceedings of the National Academy of Sciences 112, no. 13 (2015): E1624—E1631. http://dx.doi.org/10.1073/pnas.1419502112.

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Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. Recent studies have revealed potential functions for Flcn in kidney; however, kidney-specific functions for Fnip1 and Fnip2 are unknown. Here we demonstrate that Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn. We observed no detectable phenotype in Fnip2 knockout mice, whereas Fnip1 deficiency produced phenotypes similar to those seen in Flcn-deficient mice in multiple organs, but not in kidneys. We found that abs
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Inoue, Takamitsu, Jun Miyazaki, Daishi Ichioka, et al. "A comparison of nephrotoxicity between patients with a solitary-functioning kidney and those with bilateral-functioning kidneys in cisplatin-based chemotherapy for advanced urothelial carcinoma: A Japanese retrospective multi-institutional study." Journal of Clinical Oncology 36, no. 6_suppl (2018): 420. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.420.

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420 Background: To compare the prevalence of nephrotoxicity between patients with a solitary-functioning kidney versus those with bilateral-functioning kidneys during the administration of cisplatin-based chemotherapy for advanced urothelial carcinoma. Methods: We retrospectively analyzed 244 advanced urothelial carcinoma patients treated with cisplatin-based chemotherapy between 2004 and 2010 at 17 institutes in Japan. The urinary tract function status was determined based on the data of nephroureterectomy, hydronephrosis, and relief of upper urinary tract obstruction. A total of 244 patients
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Yin, Kevin, Chengfeng Liu, Michelle Bardis, et al. "Deep learning segmentation of kidneys with renal cell carcinoma." Journal of Clinical Oncology 37, no. 15_suppl (2019): e16098-e16098. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e16098.

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e16098 Background: Renal cell carcinoma (RCC) is the most common kidney malignancy and the eighth most common cancer overall, with more than 60,000 new cases and nearly 15,000 deaths in the United States each year. The majority of RCC is asymptomatic and detected incidentally on computed tomography (CT) scans performed for other indications. Multiple prior studies have highlighted the potential for a lesion to be missed or mischaracterized. Artificial intelligence (AI), the mimicking of human cognition by computers, has promise for improving radiological accuracy. Convolutional neural networks
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Blitzer, Grace, Susan Tsai, Mohammed Aldakkak, et al. "Should functional renal scans be obtained prior to upper abdominal radiation for pancreatic cancer?" Journal of Clinical Oncology 35, no. 4_suppl (2017): 442. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.442.

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442 Background: Upper abdominal irradiation for pancreas cancer is given in close proximity to the radiation sensitive kidneys. While contemporary 3D and intensity modulated radiation therapy (IMRT) can decrease the total dose of radiation delivered to the kidneys; these plans may potentially exceed the established kidney dose constraints, especially if one kidney is providing most of the renal function. Less than 10% of the general population is estimated to have asymmetrical kidney function. Functional kidney scans using MAG3 clearance can give information about the contribution of each kidn
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Li, Siyao, Lu Wen, Xiaoru Hu, Qingqing Wei, and Zheng Dong. "HIF in Nephrotoxicity during Cisplatin Chemotherapy: Regulation, Function and Therapeutic Potential." Cancers 13, no. 2 (2021): 180. http://dx.doi.org/10.3390/cancers13020180.

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Cisplatin is a highly effective, broad-spectrum chemotherapeutic drug, yet its clinical use and efficacy are limited by its side effects. Particularly, cancer patients receiving cisplatin chemotherapy have high incidence of kidney problems. Hypoxia-inducible factor (HIF) is the “master” transcription factor that is induced under hypoxia to trans-activate various genes for adaptation to the low oxygen condition. Numerous studies have reported that HIF activation protects against AKI and promotes kidney recovery in experimental models of cisplatin-induced acute kidney injury (AKI). In contrast,
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Li, Siyao, Lu Wen, Xiaoru Hu, Qingqing Wei, and Zheng Dong. "HIF in Nephrotoxicity during Cisplatin Chemotherapy: Regulation, Function and Therapeutic Potential." Cancers 13, no. 2 (2021): 180. http://dx.doi.org/10.3390/cancers13020180.

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Cisplatin is a highly effective, broad-spectrum chemotherapeutic drug, yet its clinical use and efficacy are limited by its side effects. Particularly, cancer patients receiving cisplatin chemotherapy have high incidence of kidney problems. Hypoxia-inducible factor (HIF) is the “master” transcription factor that is induced under hypoxia to trans-activate various genes for adaptation to the low oxygen condition. Numerous studies have reported that HIF activation protects against AKI and promotes kidney recovery in experimental models of cisplatin-induced acute kidney injury (AKI). In contrast,
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Kristiansson, Amanda, Anders Örbom, Oskar Vilhelmsson Timmermand, Jonas Ahlstedt, Sven-Erik Strand та Bo Åkerström. "Kidney Protection with the Radical Scavenger α1-Microglobulin (A1M) during Peptide Receptor Radionuclide and Radioligand Therapy". Antioxidants 10, № 8 (2021): 1271. http://dx.doi.org/10.3390/antiox10081271.

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α1-Microglobulin (A1M) is an antioxidant found in all vertebrates, including humans. It has enzymatic reductase activity and can scavenge radicals and bind free heme groups. Infused recombinant A1M accumulates in the kidneys and has therefore been successful in protecting kidney injuries in different animal models. In this review, we focus on A1M as a radioprotector of the kidneys during peptide receptor radionuclide/radioligand therapy (PRRT/RLT). Patients with, e.g., neuroendocrine tumors or castration resistant prostate cancer can be treated by administration of radiolabeled small molecules
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Morozova, M. V., O. A. Chekhoeva, S. S. Pyanikin, G. V. Galkin, E. A. Sokolova, and A. V. Glotov. "Multiple Primary Synchronous-Methacronous Cancer of Kidneys and Prostate Gland (Clinical Case)." Medical Visualization, no. 3 (June 28, 2017): 62–72. http://dx.doi.org/10.24835/1607-0763-2017-3-62-72.

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Primary multiple tumors are an independent emergence and development two or more neoplasms in one patient. Thus can be the struck not only different bodies of various systems, but pair bodies (mammary glands, lungs, etc.) also, and one body with multicentric defeat. Primary multiple tumors can be synchronous and metachronous. The increase in frequency of multiple neoplasms is noted in recent years.A clinical observation of a 62-year-old patient with synchronous-metachronous primary-multiple cancer of both kidney and prostate gland is presented. A feature of this observation is multiple lesions
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Printz, Carrie. "Cancer drug can damage kidneys." Cancer 116, no. 20 (2010): 4669. http://dx.doi.org/10.1002/cncr.25664.

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Khaylenko, A. V., V. A. Chernyaev, K. M. Figurin, and V. B. Matveev. "Description of a clinical case of synchronous cancer in the native and graft kidneys." Cancer Urology 13, no. 4 (2018): 122–25. http://dx.doi.org/10.17650/1726-9776-2017-13-4-122-125.

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Kidney transplantation is the most frequently performed organ transplant procedure in the world. The occurrence of malignant tumors is one of the well-known late complications of organ transplantation, which is induced by immunosuppressive therapy. In the vast majority of patients, kidney cancer occurs in the native organs; however, in a small percentage of cases, malignancies are found in the graft organ. The article describes a rare clinical case of a patient with synchronous cancer in the native and graft kidneys.
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Dissertations / Theses on the topic "Kidneys Kidneys Cancer"

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Webster, Angela C. "Immunosuppression and malignancy in end stage kidney disease." Connect to full text, 2006. http://hdl.handle.net/2123/1186.

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Thesis (Ph. D.)--University of Sydney, 2006.<br>Title from title screen (viewed 21 May 2007). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Public Health, Faculty of Medicine. Includes bibliographical references. Also available in print form.
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Meadows, Susan Dove. "PERSISTENT NEPHROTOXICITY AND RENAL TUMOR PROMOTION IN SWISS-WEBSTER MICE FOLLOWING EXPOSURE TO 1,2-DICHLOROVINYLCYSTEINE (KIDNEY, CANCER)." Thesis, The University of Arizona, 1985. http://hdl.handle.net/10150/275292.

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Yoon, Hae-seong. "A role for the tuberous sclerosis-2 tumor suppressor gene in quinol-thioether-induced nephrocarcinogenicity in the Eker rat /." Full text (PDF) from UMI/Dissertation Abstracts International, 2000. http://wwwlib.umi.com/cr/utexas/fullcit?p3004407.

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Chan, Ting-bun, and 陳霆斌. "Comparison of surgical outcomes between post-hepatectomy HCC patients with chronic kidney disease and normal kidney." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48333475.

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Based on figure from American Association for Cancer Research (2010) & Global Cancer Statistics (2011), Liver cancer (HCC) is the sixth most frequently diagnosed cancer globally and third leading cause of cancer death (Jemal, A. et al., 2011; Jemal, A., Center, M. M., DeSantis, C. et al., 2010). In Hong Kong, Liver Cancer caused 1488 deaths in 2009 in total; it is 2nd and 4th leading killer of cancer death among Hong Kong male and female respectively (Hong Kong Cancer Registry, 2010). However, surgical resection for HCC remains as mainstream treatment modality and extensive studies on post-op
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Ritchie, Robert Wilson. "Improving clinical outcomes in renal HIFU therapy." Thesis, University of Oxford, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572839.

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The rising incidence of small, asymptomatic renal tumours discovered usmg abdominal imaging during the investigation of unrelated symptoms has fuelled the desire for new therapies which avoid surgical excision. Extracorporeal High Intensity Focused Ultrasound (HIFU) was proposed as one of these modalities but so far clinical research has been ,~." inconclusive. The present work was designed to improve these clii teal outcomes through the conduct of further clinical trials, laboratory based research and the translation of new technology into existing HIFU devices. A Phase II clinical trial of p
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Lawrentschuk, Nathan Leo. "Hypoxia and angiogenesis in renal cell carcinoma." Connect to thesis, 2009. http://repository.unimelb.edu.au/10187/6790.

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Hypoxia is one of the hallmarks of cancer. It was first postulated to occur in solid tumours by Thomlinson and Gray in 1955.1 The presence of hypoxia has been demonstrated in different types of solid tumours.2 Intratumoral hypoxia is caused by the lack of functional blood vessels in proliferating tumour tissue, resulting in low intratumoral oxygen concentrations. If hypoxia is severe or prolonged, cell death occurs.3 Malignant cells can undergo genetic and adaptive changes that allow them to escape from dying of oxygen deprivation. These changes are associated with a more aggressive malignant
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Yuen, John Shyi P. "The role of the type 1 insulin-like growth factor receptor (IGF1R) in renal cancer." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670113.

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Cheung, Catherine Wing Ying. "IGF family members in renal cell carcinoma : their roles in malignancies and therapeutic interventions /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18766.pdf.

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Novaes, Marcus Vinicius Martins [UNESP]. "Efeitos renais da dexmedetomidina como adjuvante à anestesia geral combinada à anestesia peridural em pacientes oncológicos submetidos a cirurgias urológicas." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/106006.

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Made available in DSpace on 2014-06-11T19:35:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-09-21Bitstream added on 2014-06-13T18:46:37Z : No. of bitstreams: 1 novaes_mvm_dr_botfm.pdf: 501628 bytes, checksum: 9a37a15902639beaab70c281dae1e82f (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A lesão renal aguda (LRA) no período perioperatório está associada ao aumento da morbidade e da mortalidade pós-operatória. Entre as estratégias farmacológicas de prevenção encontram-se os agentes α-2 agonistas. O objetivo desta pesquisa foi avaliar o papel da dexm
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Novaes, Marcus Vinicius Martins. "Efeitos renais da dexmedetomidina como adjuvante à anestesia geral combinada à anestesia peridural em pacientes oncológicos submetidos a cirurgias urológicas /." Botucatu, 2012. http://hdl.handle.net/11449/106006.

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Orientador: Paulo do Nascimento Junior<br>Banca: Leandro Gobbo Braz<br>Banca: Geraldo Rolim Rodrigues Junior<br>Banca: Marco Aurélio marangoni<br>Banca: Luiz Vicente Garcia<br>Resumo: A lesão renal aguda (LRA) no período perioperatório está associada ao aumento da morbidade e da mortalidade pós-operatória. Entre as estratégias farmacológicas de prevenção encontram-se os agentes α-2 agonistas. O objetivo desta pesquisa foi avaliar o papel da dexmedetomidina sobre a função renal em cirurgias oncológicas urológicas através da cistatina C, creatinina e vasopressina plasmáticas. Trinta pacientes on
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Books on the topic "Kidneys Kidneys Cancer"

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Stadler, Walter Michael. Renal cancer. Demos Medical Pub., 2011.

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Carducci, Michael. The Johns Hopkins patients' guide to kidney cancer. Jones and Bartlett Publishers, 2010.

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Walczak, Janet R. The Johns Hopkins patients' guide to kidney cancer. Jones and Bartlett Publishers, 2010.

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Carducci, Michael. The Johns Hopkins patients' guide to kidney cancer. Jones and Bartlett Publishers, 2010.

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Walczak, Janet R. Johns Hopkins medicine patients' guide to kidney cancer. Jones and Bartlett Publishers, 2011.

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Bickerstaff, Linda. Kidney cancer. Rosen Pub., 2011.

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Slan, Linda C. Adult kidney cancer and Wilms' tumor. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, 1989.

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National Cancer Institute (U.S.), ed. Adult kidney cancer and Wilms' tumor. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, 1989.

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Slan, Linda C. Adult kidney cancer and Wilms' tumor. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, 1989.

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Renal cancer. Oxford University Press, 2010.

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Book chapters on the topic "Kidneys Kidneys Cancer"

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Vahlensieck, W., and N. Jaeger. "Cancer of the Kidneys." In Surgical Oncology. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-72646-0_58.

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von Morze, Cornelius, Galen D. Reed, Zhen J. Wang, Michael A. Ohliger, and Christoffer Laustsen. "Hyperpolarized Carbon (13C) MRI of the Kidneys: Basic Concept." In Methods in Molecular Biology. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-0978-1_16.

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AbstractExisting clinical markers for renal disease are limited. Hyperpolarized (HP) 13C MRI is based on the technology of dissolution dynamic nuclear polarization (DNP) and provides new avenues for imaging kidney structure, function, and most notably, renal metabolism, addressing some of these prior limitations. Changes in kidney structure and function associated with kidney disease can be evaluated using [13C]urea, a metabolically inert tracer. Metabolic changes can be assessed using [1-13C]pyruvate and a range of other rapidly metabolized small molecules, which mainly probe central carbon metabolism. Results from numerous preclinical studies using a variety of these probes demonstrated that this approach holds great potential for monitoring renal disease, although more work is needed to bridge intelligently into clinical studies. Here we introduce the general concept of HP 13C MRI and review the most relevant probes and applications to renal disease, including kidney cancer, diabetic nephropathy and ischemic kidney injury.This chapter is based upon work from the PARENCHIMA COST Action, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This introduction chapter is complemented by two separate chapters describing the experimental procedure and data analysis.
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Guermani, P., F. Alladio, M. Manzo, G. P. Segoloni, M. Messina, and D. Damiani. "Transmission of Renal Carcinomas with Cadaveric Donor Kidneys: A Five Years Follow Up." In Cancer in Transplantation: Prevention and Treatment. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0175-9_49.

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Granov, Anatoliy, Leonid Tiutin, and Thomas Schwarz. "Kidney Cancer." In Positron Emission Tomography. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-21120-1_11.

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Abouassaly, Robert, and Steven C. Campbell. "Kidney Cancer." In Geriatric Urology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-9047-0_19.

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Edwards, Luke, and Jason Hafron. "Kidney Cancer." In The Nurse Practitioner in Urology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-28743-0_18.

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Delacroix, Scott E., Surena F. Matin, John Araujo, and Christopher G. Wood. "Kidney Cancer." In 60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5197-6_13.

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Vaccaro, Mario, Claudio Guarneri, Richard F. Ambinder, et al. "Kidney Cancer." In Encyclopedia of Molecular Mechanisms of Disease. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6714.

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Yingxu, Hao. "Kidney Cancer." In Alternative and Complementary Therapies for Cancer. Springer US, 2010. http://dx.doi.org/10.1007/978-1-4419-0020-3_12.

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Gospodarowicz, M. K. "Kidney Cancer." In Manual of Clinical Oncology. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-85159-9_28.

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Conference papers on the topic "Kidneys Kidneys Cancer"

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Les, T., T. Markiewicz, M. Dziekiewicz, and M. Lorent. "Automatic system for the renal and cancer segmentation in CT images." In 2019 Kidney Tumor Segmentation Challenge: KiTS19. University of Minnesota Libraries Publishing, 2019. http://dx.doi.org/10.24926/548719.092.

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Liu, Yubai, Fucang Jia, and Shouliang Qi. "Minimal Information Loss Attention U-Net for abdominal CT of kidney cancers segmentation." In 2019 Kidney Tumor Segmentation Challenge: KiTS19. University of Minnesota Libraries Publishing, 2019. http://dx.doi.org/10.24926/548719.030.

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Haven, B. A., D. K. Yamagata, M. Kurosaka, S. Yamawaki, and T. Maya. "Anti-Kidney Pair of Vortices in Shaped Holes and Their Influence on Film Cooling Effectiveness." In ASME 1997 International Gas Turbine and Aeroengine Congress and Exhibition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/97-gt-045.

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The difference in film cooling effectiveness of three shaped holes is hereby explained by their vortical structures. Highlighted, in particular, are the competing effects of two pairs of vortices present in jets: the so-called kidney-shaped pair of vortices and a newly found anti-kidney pair. Three shaped holes investigated were referred to as TP2, TP3, and TP4. Except for the difference of how the hole area is increased, they are essentially the same. At the higher blowing ratio, the film cooling effectiveness of TP4 was found to be far superior to those of either TP2 and TP3. By flow visuali
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John, Subhashini. "High precision radiotherapy for vulvar cancer in post renal transplantation: Dosimetric challenges." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685369.

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Background: Patients with renal transplant have a higher incidence of various malignancies. Delivery of adequate radiation dose to the pelvic target in such patients sparing the transplanted kidney is a dosimetric ordeal. Due to lack of sufficient data in the literature regarding the dose constraint of the transplanted pelvic kidney, plan evaluation becomes extremely challenging in this situation. Here we present comparative dosimetric plan evaluation data of treating a patient with carcinoma of the vulva with transplanted kidney. Methods: We compared 3D conformal radiotherapy (3DCRT) and Inte
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Bitkower, Jay. "Abstract LB-61:Trends in Kidney Cancer." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-61.

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Treado, P. J., S. Stewart, S. Augustine, H. Kirschner, J. Cohen, and A. Opong. "Molecular Chemical Imaging of Kidney Cancer Tumor Margins." In Biomedical Optics. OSA, 2014. http://dx.doi.org/10.1364/biomed.2014.bs3a.1.

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Kundu, Anirban, Eun-Young Kho, Sandeep B. Shelar, et al. "Abstract 4483: Functional implications ofPRDM16loss in kidney cancer." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-4483.

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Hadjiyski, Nathan. "Kidney Cancer Staging: Deep Learning Neural Network Based Approach." In 2020 International Conference on e-Health and Bioengineering (EHB). IEEE, 2020. http://dx.doi.org/10.1109/ehb50910.2020.9280188.

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Vázquez, Sergio. "I ICWM: Microbiota and Kidney Cancer. Dr. Sergio Vázquez." In MOL2NET 2019, International Conference on Multidisciplinary Sciences, 5th edition. MDPI, 2019. http://dx.doi.org/10.3390/mol2net-05-06748.

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Fahy, Maria T. "Abstract LB-39: Kidney cancer association fighting back togethe." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-lb-39.

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Reports on the topic "Kidneys Kidneys Cancer"

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Morani, Ajaykumar, Ahmad Mubarak, and Raghunandan Vikram. Imaging and kidney cancer. BJUI Knowledge, 2019. http://dx.doi.org/10.18591/bjuik.0097.

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Michael Pirrung, Michael Pirrung. Synthesis of a Kidney Cancer Drug. Experiment, 2013. http://dx.doi.org/10.18258/0426.

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Torti, Suzy V. Targeted Nanoparticles for Kidney Cancer Therapy. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada569284.

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Torti, Suzy V. Targeted Nanoparticles for Kidney Cancer Therapy. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada569286.

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Frisch, Steven. Role of Grainyhead in Kidney Cancer. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada599266.

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Pantuck, Allan. Early Diagnosis of Clear Cell Kidney Cancer via VHL/HIF Pathway-regulated Circulating microRNA. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada599473.

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The evolution of metastatic kidney cancer treatment: from interferons to the novel immunotherapies. BJUI Knowledge, 2017. http://dx.doi.org/10.18591/bjuik.0107.

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