Relevant bibliographies by topics / Killer cell immunoglobulin like receptors (KIR)

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Killer cell immunoglobulin like receptors (KIR)'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Killer cell immunoglobulin like receptors (KIR).'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Killer cell immunoglobulin like receptors (KIR)"

1

Hidajat, Melanny, Dominik Selleslag, Achiel Van Hoof, Jan Van Droogenbroeck, Johan Billiet, and Arnold Criel. "Killer Immunoglobulin-Like Receptors (KIRs) Genotypes in a Belgian Population." Blood 104, no. 11 (2004): 3852. http://dx.doi.org/10.1182/blood.v104.11.3852.3852.

Full text
Abstract:
Abstract KIRs (Killer cell Immunoglobulin-like Receptors) are expressed on NK (Natural Killer) cells and a subpopulation of T lymphocytes namely memory CD8+ T cells. The distribution of KIR genes varies among individuals and populations. These genes are encoded on chromosome 19 (19q13.4). Till now 17 KIR genes and pseudogenes have been identified. KIRs recognise groups of HLA class I alleles. NK activity is partially controlled through the interaction between KIRs and their HLA ligands. Several studies report that KIRs may affect the outcome of Hematopoietic Stem-Cell Transplantations. We perf
APA, Harvard, Vancouver, ISO, and other styles
2

Cremer, Anja, Ute Heider, Stefan Tomiuk, et al. "Integrated Genotyping and mRNA Expression Profiling of Killer Immunoglobulin-Like Receptors." Blood 106, no. 11 (2005): 3909. http://dx.doi.org/10.1182/blood.v106.11.3909.3909.

Full text
Abstract:
Abstract Natural killer (NK) cells belong to a subgroup of lymphocytes (CD3-CD56+) which play an important role in the cellular immune response against virus-infected cells and tumors. The activity of NK cells is regulated by a balance of triggering and inhibitory receptors, including Killer Ig-like Receptor (KIR) molecules which interact with specific HLA class I molecules, predominantly HLA-C, on target cells. The 17 known KIR genes are divided into two classes: activating KIRs and inhibitory KIRs. There is strong evidence that inhibitory KIR mismatch between donor and recipient improves the
APA, Harvard, Vancouver, ISO, and other styles
3

Luc-Aimé, Kagoué Simeni, Yindom Louis-Marie, Loni Ekali Gabriel, Clauvis Kunkeng Yengo, F. Esemu Livo, and Nguedia Jules Clement Assob. "Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon." Journal of Immunology Research 2021 (January 13, 2021): 1–7. http://dx.doi.org/10.1155/2021/9053280.

Full text
Abstract:
The biological reason(s) behind persistent mother-to-child transmission (MTCT) of HIV (albeit at reduced rate compared to the preantiretroviral therapy era) in spite of the successful implementation of advanced control measures in many African countries remains a priority concern to many HIV/AIDS control programs. This may be partly due to differences in host immunogenetic factors in highly polymorphic regions of the human genome such as those encoding the killer-cell immunoglobulin-like receptor (KIR) molecules which modulate the activities of natural killer cells. The primary aim of this stu
APA, Harvard, Vancouver, ISO, and other styles
4

Fauriat, Cyril, Martin A. Ivarsson, Hans-Gustaf Ljunggren, Karl-Johan Malmberg, and Jakob Michaëlsson. "Education of human natural killer cells by activating killer cell immunoglobulin-like receptors." Blood 115, no. 6 (2010): 1166–74. http://dx.doi.org/10.1182/blood-2009-09-245746.

Full text
Abstract:
Abstract Expression of inhibitory killer cell immunoglobulin-like receptors (KIRs) specific for self–major histocompatibility complex (MHC) class I molecules provides an educational signal that generates functional natural killer (NK) cells. However, the effects of activating KIRs specific for self-MHC class I on NK-cell education remain elusive. Here, we provide evidence that the activating receptor KIR2DS1 tunes down the responsiveness of freshly isolated human NK cells to target cell stimulation in donors homozygous for human leukocyte antigen (HLA)–C2, the ligand of KIR2DS1. The tuning was
APA, Harvard, Vancouver, ISO, and other styles
5

Rettman, Pauline, Matthew D. Blunt, Rebecca J. Fulton, et al. "Peptide: MHC-based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors." Journal for ImmunoTherapy of Cancer 9, no. 5 (2021): e001912. http://dx.doi.org/10.1136/jitc-2020-001912.

Full text
Abstract:
BackgroundNatural killer (NK) cells are increasingly being recognized as agents for cancer immunotherapy. The killer cell immunoglobulin-like receptors (KIRs) are expressed by NK cells and are immunogenetic determinants of the outcome of cancer. In particular, KIR2DS2 is associated with protective responses to several cancers and also direct recognition of cancer targets in vitro. Due to the high homology between activating and inhibitory KIR genes to date, it has been challenging to target individual KIR for therapeutic benefit.MethodsA novel KIR2DS2-targeting therapeutic peptide:MHC DNA vacc
APA, Harvard, Vancouver, ISO, and other styles
6

Parham, Peter, Paul J. Norman, Laurent Abi-Rached, and Lisbeth A. Guethlein. "Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules." Philosophical Transactions of the Royal Society B: Biological Sciences 367, no. 1590 (2012): 800–811. http://dx.doi.org/10.1098/rstb.2011.0266.

Full text
Abstract:
In placental mammals, natural killer (NK) cells are a population of lymphocytes that make unique contributions to immune defence and reproduction, functions essential for survival of individuals, populations and species. Modulating these functions are conserved and variable NK-cell receptors that recognize epitopes of major histocompatibility complex (MHC) class I molecules. In humans, for example, recognition of human leucocyte antigen (HLA)-E by the CD94:NKG2A receptor is conserved, whereas recognition of HLA-A, B and C by the killer cell immunoglobulin-like receptors (KIRs) is diversified.
APA, Harvard, Vancouver, ISO, and other styles
7

Treanor, Bebhinn, Peter M. P. Lanigan, Sunil Kumar, et al. "Microclusters of inhibitory killer immunoglobulin–like receptor signaling at natural killer cell immunological synapses." Journal of Cell Biology 174, no. 1 (2006): 153–61. http://dx.doi.org/10.1083/jcb.200601108.

Full text
Abstract:
We report the supramolecular organization of killer Ig–like receptor (KIR) phosphorylation using a technique applicable to imaging phosphorylation of any green fluorescent protein–tagged receptor at an intercellular contact or immune synapse. Specifically, we use fluorescence lifetime imaging (FLIM) to report Förster resonance energy transfer (FRET) between GFP-tagged KIR2DL1 and a Cy3-tagged generic anti-phosphotyrosine monoclonal antibody. Visualization of KIR phosphorylation in natural killer (NK) cells contacting target cells expressing cognate major histocompatibility complex class I pro
APA, Harvard, Vancouver, ISO, and other styles
8

Abi-Rached, Laurent, and Peter Parham. "Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues." Journal of Experimental Medicine 201, no. 8 (2005): 1319–32. http://dx.doi.org/10.1084/jem.20042558.

Full text
Abstract:
Expression of killer cell Ig-like receptors (KIRs) diversifies human natural killer cell populations and T cell subpopulations. Whereas the major histocompatibility complex class I binding functions of inhibitory KIR are known, specificities for the activating receptors have resisted analysis. To understand better activating KIR and their relationship to inhibitory KIR, we took the approach of reconstructing their natural history and that of Ly49, the analogous system in rodents. A general principle is that inhibitory receptors are ancestral, the activating receptors having evolved from them b
APA, Harvard, Vancouver, ISO, and other styles
9

Rajagopalan, Sumati, and Eric O. Long. "Understanding how combinations of HLA and KIR genes influence disease." Journal of Experimental Medicine 201, no. 7 (2005): 1025–29. http://dx.doi.org/10.1084/jem.20050499.

Full text
Abstract:
Combinations of HLA and killer cell immunoglobulin–like receptor (KIR) genes have been associated with diseases as diverse as autoimmunity, viral infections, reproductive failure, and now cancer. Much as early observations of disease associations with HLA polymorphism preceded a detailed knowledge of HLA recognition by T cell receptors, the recently reported disease associations with HLA–KIR gene combinations beg for a better understanding of the underlying mechanisms.
APA, Harvard, Vancouver, ISO, and other styles
10

Gumá, Mónica, Ana Angulo, Carlos Vilches, Natalia Gómez-Lozano, Núria Malats, and Miguel López-Botet. "Imprint of human cytomegalovirus infection on the NK cell receptor repertoire." Blood 104, no. 12 (2004): 3664–71. http://dx.doi.org/10.1182/blood-2004-05-2058.

Full text
Abstract:
Expression of the activating CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E was analyzed in peripheral blood lymphocytes (PBLs) from healthy adult blood donors; the expression of other natural killer (NK) cell receptors (ie, CD94/NKG2A, KIR, CD85j, CD161, NKp46, NKp30, and NKG2D) was also studied. Human cytomegalovirus (HCMV) infection as well as the HLA-E and killer immunoglobulin-like receptor (KIR) genotypes were considered as potentially relevant variables associated with CD94/NKG2C expression. The proportion of NKG2C+ lymphocytes varied within a wide range (<0.1% t
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Killer cell immunoglobulin like receptors (KIR)"

1

Sepulveda, Christian Alberto Garcia. "Killer cell Immunoglobulin-like Receptor (KIR) polymorphism : functional implications and clinical relevance." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444690/.

Full text
Abstract:
NK cell function is regulated by Killer-cell Immunoglobulin-like Receptors (KIR) some of which recognise class I Major Histocompatibility Complex molecules. KIRs have been shown to exhibit a high degree of functional diversity which is generated at several levels. However, the functional relevance of this diversity remains largely unknown. This thesis describes our approach towards elucidating the functional relevance of KIR diversity. To study this we first compiled all known KIR sequences into a database. We developed bioinformatics tools to facilitate the study of these sequences and have m
APA, Harvard, Vancouver, ISO, and other styles
2

Foley, Bree Amanda. "The immunogenetics of natural killer cell alloreactivity." University of Western Australia. School of Pathology and Laboratory Medicine, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0242.

Full text
Abstract:
[Truncated abstract] Natural killer (NK) cell alloreactivity can be exploited in haploidentical haematopoietic stem cell transplantation (HSCT) to improve graft survival, reduce graft versus host disease and decrease leukaemic relapse. NK cells lyse cells that have reduced expression of class I HLA molecules. In an allogeneic setting, donor NK cells may be activated by the absence of donor (self) class I HLA molecules on recipient cells; the absence of self-epitopes being detected by inhibitory KIR receptors on donor NK cells. The way in which genetic polymorphism of the receptors and ligands
APA, Harvard, Vancouver, ISO, and other styles
3

Salim, Patrícia Hartstein. "Estudo do polimorfismo dos genes KIR na esclerose sistêmica." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/15457.

Full text
Abstract:
As células Natural Killer (NK) fazem parte da resposta imune inata, sendo a primeira linha de defesa do organismo contra vírus, bactérias, tumores e microorganismos. Estas células induzem a morte da célula-alvo quando não há o reconhecimento das moléculas de antígenos leucocitários humanos (HLA) de classe I, através de seus receptores, chamados Killer cell Immunoglobulin-like Receptor (KIR). Vários estudos demonstram o envolvimento dos genes KIR na patogênese das doenças auto-imunes. Acredita-se que combinações desses genes possam ser favoráveis para o desenvolvimento da esclerose sistêmica (E
APA, Harvard, Vancouver, ISO, and other styles
4

Silva, Pamela Portela da. "Análise de polimorfismos dos genes KIR e HLA classe I em pacientes com câncer colorretal." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/148088.

Full text
Abstract:
O câncer colorretal (CCR) pode ocorrer em qualquer parte do cólon ou do reto e representa o terceiro câncer mais comum no mundo em ambos os sexos. As células Natural Killer (NK) fazem parte do sistema imune inato reconhecendo moléculas de HLA de classe I em células alvo, através de seus receptores de membrana killer cell immunoglobulin-like receptors (KIR). O objetivo deste estudo foi avaliar a associação entre os genes KIR e os ligantes HLA em pacientes com câncer colorretal e controles saudáveis. Examinamos o polimorfismo de 16 genes KIR e seus ligantes HLA em 154 pacientes caucasóides com C
APA, Harvard, Vancouver, ISO, and other styles
5

Ichise, Hiroshi. "NK cell alloreactivity against KIR-ligand-mismatched HLA-haploidentical tissue derived from HLA haplotype-homozygous iPSCs." Kyoto University, 2017. http://hdl.handle.net/2433/228232.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Silva, Pamela Portela da. "Estudo de polimorfismos dos genes KIR e HLA em pacientes com câncer de próstata." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/35890.

Full text
Abstract:
O câncer de próstata é o segundo câncer mais comum entre homens, uma vez que tanto a incidência como a mortalidade aumentam exponencialmente após a idade de 50 anos. As células Natural Killer (NK) fazem parte do sistema imune inato e reconhecem moléculas de HLA de classe I na célula alvo, através de seus receptores de membrana, chamados killer immunoglobulin-like-receptors (KIR). O objetivo desse estudo foi avaliar a associação entre os genes KIR e HLA em pacientes com câncer de próstata e grupo controle. Genotipamos 200 pacientes com diagnóstico de câncer de próstata e 185 pacientes saudáveis
APA, Harvard, Vancouver, ISO, and other styles
7

Jobim, Maria Regina Sampaio Leite. "Estudo do polimorfismo dos genes KIR e HLA em pacientes com câncer de mama e grupo controle." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/97026.

Full text
Abstract:
O presente estudo tem como objetivo investigar a frequência dos diversos polimorfismos dos genes KIR (Killer Immunoglobulin-like Receptors) e HLA C1 e C2 em um grupo de pacientes com câncer de mama e comparar com um grupo controle de indivíduos sadios. As células natural killer (NK) são linfócitos que diferem das células T e B e que fazem parte da imunidade natural, reconhecendo as moléculas HLA (Antígenos Leucocitários Humano) de classe I em células infectadas por vírus ou em células tumorais, através de seus receptores de membrana. Os principais receptores das células NK são conhecidos como
APA, Harvard, Vancouver, ISO, and other styles
8

Kruse, Philip Hermann Verfasser], Lutz [Akademischer Betreuer] Walter, Jürgen [Akademischer Betreuer] [Wienands, and Wolfgang [Akademischer Betreuer] Engel. "Genetic and functional characterisation of killer cell immunoglobulin like receptors (KIR) of rhesus macaques (Macaca mulatta) / Philip Hermann Kruse. Gutachter: Lutz Walter ; Jürgen Wienands ; Wolfgang Engel. Betreuer: Lutz Walter." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2011. http://d-nb.info/1042640025/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Martin, Hilmar. "Evaluation von KIR-Liganden Inkompatibilität bei unverwandten Knochenmark-/ Stammzelltransplantationen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2005. http://nbn-resolving.de/urn:nbn:de:swb:14-1124306558415-94790.

Full text
Abstract:
We performed a retrospective study in 185 patients with myelogenous leukemias who had received hematopoietic cells from unrelated donors. The aim of this study was to answer the question wether the benefit of KIR ligand incompatibility seen in haploidentical tranplantations can also be seen using unrelated donors. We could not detect a significant difference in survival between patients with a KIR ligand incompatibility and those with either fully matched or partially mismatched unrelated donors in this patient cohort<br>In der Therapie von Leukämien ist die Knochenmark- bzw. Stammzelltranspla
APA, Harvard, Vancouver, ISO, and other styles
10

Yindom, Louis Marie. "Human Leukocyte Antigen (HLA) and Killer Immunoglobulin-like Receptors (KIR) in HIV-2 Infection." Thesis, Open University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520671.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Killer cell immunoglobulin like receptors (KIR)"

1

Hou, Lihua, Minghua Chen, Noriko Steiner, Kanthi Kariyawasam, Jennifer Ng, and Carolyn K. Hurley. "Killer Cell Immunoglobulin-Like Receptors (KIR) Typing by DNA Sequencing." In Methods in Molecular Biology™. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-842-9_25.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Li, Hongchuan, Paul W. Wright, and Stephen K. Anderson. "Identification and Analysis of Novel Transcripts and Promoters in the Human Killer Cell Immunoglobulin-like Receptor (KIR ) Genes." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-362-6_26.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Long, Eric O., Deborah N. Burshtyn, Christopher C. Stebbins, and Carsten Watzl. "How do killer cell Ig-like receptors inhibit natural killer cells?" In Activating and Inhibitory Immunoglobulin-like Receptors. Springer Japan, 2001. http://dx.doi.org/10.1007/978-4-431-53940-7_29.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Rajalingam, Raja, Sarah Cooley, and Jeroen van Bergen. "Killer Cell Immunoglobulin-Like Receptors in Clinical Transplantation." In Manual of Molecular and Clinical Laboratory Immunology. ASM Press, 2016. http://dx.doi.org/10.1128/9781555818722.ch119.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Rajalingam, Raja, and Elham Ashouri. "Gene-Specific PCR Typing of Killer Cell Immunoglobulin-Like Receptors." In Methods in Molecular Biology. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-493-7_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Ruggeri, Loredana, Shuhong Zhang, and Sherif S. Farag. "Natural Killer Cell Activity and Killer Immunoglobulin-Like Receptors in Hematopoietic Stem Cell Transplantation." In Cancer Treatment and Research. Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-78580-6_3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

"Killer Immunoglobulin-Like Receptors (KIR)." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100688.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

"Killer Immunoglobulin-Like Receptors (KIR)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_105437.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Rajalingam, Raja, and Elham Ashouri. "Killer Cell Immunoglobulin-like Receptors in Health and Disease." In The HLA Complex in Biology and Medicine: A Resource Book. Jaypee Brothers Medical Publishers (P) Ltd., 2010. http://dx.doi.org/10.5005/jp/books/11170_24.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Killer cell immunoglobulin like receptors (KIR)"

1

Chan, Daniel C. F., Zhiyong Zhang, Hong Wang, et al. "Abstract 3656: Therapeutic effects of anti-KIR antibodies against metastatic cancer cells with aberrant expression of Natural Killer-Cell Immunoglobulin-like Receptors (KIRs)." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3656.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Chan, Daniel C., Zhiyong Zhang, Di Zheng, et al. "Abstract 4836: Immune-tolerance due to aberrant expression of Natural Killer-Cell Immunoglobulin-like Receptors (KIRs) on cancer cells and enhanced cancer-platelet interactions." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4836.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Chan, Daniel C., Zhiyong Zhang, Hong Wang, et al. "Abstract 1357: Role of Natural Killer-cell Immunoglobulin-like receptors KIR2DL1 and KIR3DL1 in immune resistance." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1357.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Hagberg, N., D. Leonard, G. Nordmark, and L. Rönnblom. "PS1:16 The presence of autoantibodies to multiple killer cell immunoglobulin-like receptors is associated with nephritis in sle patients." In 11th European Lupus Meeting, Düsseldorf, Germany, 21–24 March 2018, Abstract presentations. Lupus Foundation of America, 2018. http://dx.doi.org/10.1136/lupus-2018-abstract.64.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Killer cell immunoglobulin like receptors (KIR)"

1

Varbanova, Viktoria, Snejina Mihailova, Elissaveta Naumova, and Anastasiya Mihaylova. Distribution of Killer-cell Immunoglobulin-like Receptors (KIR) and their HLA Class I Ligands in the Bulgarian Population. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2020. http://dx.doi.org/10.7546/crabs.2020.07.14.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Killer cell immunoglobulin like receptors (KIR)' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography