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1

Parker, Jonathan. "Geronticide: Killing the Elderly." Journal of Adult Protection 4, no. 4 (2002): 45–46. http://dx.doi.org/10.1108/14668203200200030.

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2

Hiskey, Syd. "Book Review: Geronticide: Killing the Elderly." International Review of Victimology 8, no. 3 (2001): 298–99. http://dx.doi.org/10.1177/026975800100800305.

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3

Biggs, Hazel. "Book Review: Geronticide: Killing the Elderly." Social & Legal Studies 11, no. 4 (2002): 595–97. http://dx.doi.org/10.1177/096466390201100410.

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4

Prins, Herschel. "Book Review: Geronticide: Killing the Elderly." Probation Journal 48, no. 3 (2001): 229–30. http://dx.doi.org/10.1177/026455050104800318.

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5

Brahmi, Abderrazzaq. "The International Legal Characterization of the Crimes of the Zionist Entity against Palestinians; Operation Al-Aqsa Flood as a Model." Science, Education and Innovations in the Context of Modern Problems 8, no. 2 (2025): 228–39. https://doi.org/10.56334/sei/8.2.17.

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The cowardly Zionist entity justified its recent aggression against the Gaza Strip through bombings, destruction, and killings, claiming these actions were part of its legal exercise of the right to self-defense, particularly citing legitimate self-defense under Article 51 of the United Nations Charter. This was ostensibly in response to the recent "Operation Al-Aqsa Flood." The entity used this reasoning to justify its deployment of force, aerial and ground bombardments of cities and residential neighborhoods in Gaza, and the killing of innocent civilians, including children, women, the elder
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6

Jiang, Yao, Andrew D. Southam, Sandro Trova, et al. "Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing." British Journal of Cancer 126, no. 2 (2021): 275–86. http://dx.doi.org/10.1038/s41416-021-01570-z.

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Abstract Background We previously demonstrated the in vitro killing of AML cells by the combination of the lipid-lowering agent bezafibrate (BEZ) and the contraceptive hormone medroxyprogesterone acetate (MPA). A phase II trial demonstrated in vivo safety and efficacy of BEZ and MPA (BaP) in elderly, relapsed/refractory AML and high-risk myelodysplastic syndrome (MDS) patients. However, we observed dose-limiting toxicities in a second trial that attempted to improve outcomes via escalation of BaP doses. Thus we sought to identify a third repurposed drug that potentiates activity of low dose Ba
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7

Post, Stephen G. "Infanticide and Geronticide." Ageing and Society 10, no. 3 (1990): 317–28. http://dx.doi.org/10.1017/s0144686x0000831x.

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ABSTRACTThis essay considers recent ethical literatures on the question of the direct killing of newborns and of the severely demented elderly. At various points, the arguments in these literatures are brought together for comparison and contrast. Finally, a constructive argument against infanticide and geronticide is developed.
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8

Andrews, June. "Geronticide: Killing the ElderlyGeronticide: Killing the Elderly Mike Brogden Jessica Kingsley Publishers 221pp £15.95 1 85302 709 X 185302709X." Nursing Older People 13, no. 5 (2001): 36. http://dx.doi.org/10.7748/nop.13.5.36.s25.

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9

Ambade, Vipul Namdeorao, Jaydeo Laxman Borkar, and Satin Kalidas Meshram. "Homicide by direct snake bite: a case of contract killing." Medicine, Science and the Law 52, no. 1 (2011): 40–43. http://dx.doi.org/10.1258/msl.2011.011020.

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It has been estimated that five million snake bite cases occur worldwide every year, causing about 100,000 deaths. Snake bite is exclusively accidental in nature. Suicide by snake bite is very rare and homicidal snake bite is not reported. In the present case, a contract killer was hired, who used a poisonous snake to kill an elderly couple by way of direct snake bite. We believe this to be the first case reported where a snake was directly used for the murder of two victims through a contract killer.
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10

Ковилоски, Славчо. "KILLING OF THE ELDERLY: THE MACEDONIAN CUSTOM “SLAUGHTER OF THE OLD MEN”." PHILOLOGICAL STUDIES 22, no. 2 (2024): 1–16. http://dx.doi.org/10.55302/ps2422201k.

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11

Vukušić, Ana-Marija. "Anything Can be Endured, Except Loneliness, Loneliness is Killing Me..." Etnološka istraživanja, no. 29 (December 23, 2024): 225–39. https://doi.org/10.32458/ei.29.10.

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The author deals with the problems of isolation and loneliness in rural, sparsely populated parts of Croatia based on the findings of research conducted in the Dalmatian Hinterland. The first part of the article is dedicated to selected theoretical insights on social isolation and loneliness, and then, by presenting the comments of people she met in the field on their own everyday life, the author deals with the diversity or subjective characteristics of the ways in which loneliness and isolation (as well as the related feelings of uselessness, feeling “redundant” and insecurity in existing re
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12

Mary, Finch. "Geronticide: killing the elderly Mike Brogden Geronticide: Kiling The Elderly Jessica Kingsley Publishers £15.95 1 85302 700 X 185302700X." Nursing Standard 15, no. 34 (2001): 29. http://dx.doi.org/10.7748/ns.15.34.29.s49.

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13

Olmo-Fontánez, Angélica M., and Joanne Turner. "Tuberculosis in an Aging World." Pathogens 11, no. 10 (2022): 1101. http://dx.doi.org/10.3390/pathogens11101101.

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Tuberculosis (TB) is one of the leading causes of death due to its being an infectious disease, caused by the airborne pathogen Mycobacterium tuberculosis (M.tb). Approximately one-fourth of the world’s population is infected with latent M.tb, and TB is considered a global threat killing over 4000 people every day. The risk of TB susceptibility and mortality is significantly increased in individuals aged 65 and older, confirming that the elderly represent one of the largest reservoirs for M.tb infection. The elderly population faces many challenges that increase their risk of developing respir
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14

Catherine, Oluyemo. "Emergency use of Human Parts as Money Rituals for Instant Riches: A Contradiction to Human Dignity and Cultural Fundamental Principles in South West, Nigeria." International Journal of Innovative Science and Research Technology 7, no. 12 (2023): 1369–79. https://doi.org/10.5281/zenodo.7525165.

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The emergency use of human body parts as money rituals for quick fortune violates both cultural and human dignity in Nigeria. It is an impediment to societal growth. The phrase "money ritual" describes a situation in Nigeria where a person is killed and then their body parts are harvested and allegedly used for ritualpurposes.The objectives of the study are to investigate the causes of the hazard in South West,the frequency of emergency use of human parts as money rituals, the public's perception of the use of human parts and money rituals, and the best course of action for elimi
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15

Salari, Sonia, Carrie Sillito, and Emma Videla. "GENDER-BASED VIOLENCE IN HOMICIDE–SUICIDE EVENTS: A CALL FOR ADHERENCE TO THE CDC DEFINITION FOR “MERCY KILLING”." Innovation in Aging 7, Supplement_1 (2023): 560–61. http://dx.doi.org/10.1093/geroni/igad104.1838.

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Abstract Intimate partner homicide suicide (IPHS) events are overwhelmingly male perpetrated (90%). Gender-based violence (GBV) prevention requires ‘best practices’ for media reporting. Consider the following: In a patient room of a busy hospital, an overwhelmed man (71) suicided after firing shots at his wife (70) who had survived a stroke. The gunfire caused trauma among witnesses. Media reports used the term ‘mercy killing,’ but critical ingredients were missing. The CDC’s NVDRS (2022) defines ‘mercy killing’ as “…Killed, at the victim’s request…to end…pain or distress…Do not assume…murder/
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16

Bakhtin, V. V., and A. A. Pripadchev. "Old People as a Special Category of Victims Nazi Crimes." Proceedings of Southwest State University. Series: History and Law 13, no. 4 (2023): 217–34. http://dx.doi.org/10.21869/2223-1501-2023-13-4-217-234.

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Relevance. Currently, there is an increased interest in the tragedy of the civilian population in Russian society. This is reflected both in numerous scientific publications and in procedural actions. Belgorod, Voronezh, Oryol regional courts recognized the war crimes of the Nazis and their accomplices as genocide.Purpose: to consider, based on the materials of the Extraordinary State Commission of Federal and Regional Archives, a special category of victims of Nazi crimes – the elderly.Objectives: to determine the criteria of old age, to find out the number of victims of crimes – the elderly
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17

Jones, Lynne. "The medicine of misery: A personal account." Bulletin of the Royal College of Psychiatrists 12, no. 8 (1988): 331–32. http://dx.doi.org/10.1192/s0140078900021003.

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We spent part of this morning's ward round making a priority list; which of the five patients in need of admission was most acute, which could wait. There are two elderly ladies, both living alone, both very depressed. Edith is no longer taking care of herself, picking at her skin to the point where nasty sores have formed, and pulling her eyebrows out in her distress. Jonathan should have been admitted last week, we delayed and he took an overdose of Ativan. Alan is an elderly man who gets recurrent depressions. They seem to resolve of their own accord without medication if only he can be adm
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18

Zeppegno, P., and C. M. Gramaglia. "Homicide and Suicide in the Elderly." European Psychiatry 65, S1 (2022): S34—S35. http://dx.doi.org/10.1192/j.eurpsy.2022.122.

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Homicide and suicide are complex phenomena raising questions and interest which go far beyond the medical and psychiatric field, as they represent a challenge for an understanding which is, first of all, human. In older adults, homicide and suicide may present together in the homicide-suicide phenomenon. The most common motive underlying this behavior in intimate partner relationships is the so-called “mercy killing”, where the perpetrator kills the partner to eventually allow relief from declining health conditions, and then commits suicide. Actually, older adults account for a disproportiona
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19

TOMA, Sebastian Ionut, Barabas BARNA, Daniel TABIAN, Calin SCRIPCARU, Marius Alexandru MOGA, and Diana BULGARU-ILIESCU. "Homicidal Act Commited by an Elderly Person with Sexual Dysfunction - Case Report." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 11, no. 3 Sup.1 (2020): 08–19. https://doi.org/10.18662/brain/11.3Sup1/117.

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Sexual dysfunctions (SDs) are highly prevalent with aging.Studies reported an interactive correlation between psychiatric morbidityand SD. Also, SDs have significant influence on patients` self-esteem,body image, interpersonal relationships, and physical health in general.The aim of the present research is to present an intimate partner homicidecase and to discuss a possible correlation between SDs of elderly patientsand their inclination towards aggressive behavior from intimate partnerviolence (IPV).A forensic psychiatric assessment was performed on a married malepatient, aged 61. He was dia
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20

Stewart, Lygia, J. McLeod Grifiss, Gary A. Jarvis та Lawrence W. Way. "Elderly patients have more severe biliary infections: Influence of complement-killing and induction of TNFα production". Surgery 143, № 1 (2008): 103–12. http://dx.doi.org/10.1016/j.surg.2007.06.035.

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21

STEWART, L., J. GRIFFISS, G. JARVIS, and L. WAY. "Elderly patients have more severe biliary infections: Influence of complement-killing and induction of TNF-? production." Journal of Gastrointestinal Surgery 9, no. 4 (2005): 545–46. http://dx.doi.org/10.1016/j.gassur.2005.01.066.

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22

Garner, Jane. "Geronticide: killing the elderly. edited by Mike Brogden. Jessica Kingsley Publishers, London, 2001. Pages: 221. £15.95." International Journal of Geriatric Psychiatry 17, no. 10 (2002): 983. http://dx.doi.org/10.1002/gps.701.

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23

Ostrovskaya, Helena P. "Interpretation of Euthanasia in the Buddhist Worldview." Письменные памятники Востока 21, no. 2 (2024): 43–52. http://dx.doi.org/10.55512/wmo632338.

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Religious interpretations of the moral aspect of euthanasia arouse serious scholarly interest in the problematic field of bioethics. The article is devoted to the explication of the Buddhist approach to the ethical assessment of euthanasia based on the material of Encyclopedia of Abhidharma with Commentary, an exegetical work by the famous educator Vasubandhu (4th–5th centuries) . A thematic analysis of the text reveals two different types of euthanasia discussed by Buddhist exegetes. One of them is characterized as the foreign practice of killing terminally ill parents in order to save them f
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24

Hyoju, Sanjiv K. "Modification of Sympathetic and Hypothalamic Responses to Prevent Complications of COVID-19: “Dam and Wall Concept”." Stresses 3, no. 1 (2023): 153–66. http://dx.doi.org/10.3390/stresses3010012.

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We are in the midst of the COVID-19 pandemic. Since December 2019, severe acute respiratory coronavirus (SARS-CoV-2) has infected more than half a billion people, killing nearly 7 million people worldwide. Now various variants of SARS-CoV-2 are causing mayhem and driving the global surge. Epidemiologists are aware of the fact that this virus is capable of escaping immunity and likely to infect the same person multiple times despite adequate vaccination status. Elderly people and those with underlying health conditions who are considered high-risk are likely to suffer complications. While it is
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25

Ahmed, AG, and Robin PD Menzies. "Homicide in the Canadian Prairies: Elderly and Nonelderly Killings." Canadian Journal of Psychiatry 47, no. 9 (2002): 875–79. http://dx.doi.org/10.1177/070674370204700910.

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Objective: To examine the psychosocial and clinical characteristics of male perpetrators of elderly and nonelderly homicides in the Canadian Prairies. Method: We examined data drawn from a study of 901 adult homicide offenders who were incarcerated or on parole between 1988 and 1992 in Alberta, Saskatchewan, and Manitoba. Results: Of those studied, 67 men were convicted of homicide involving 79 elderly victims, and 671 were convicted of homicide involving 675 nonelderly victims. Most perpetrators were single and engaged in irregular patterns of employment at the time of their index offence. Fo
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26

Tsai, Y. F., Y. J. Chen, S. H. Lee, and H. L. Lee. "479 – Opinions about elderly suicide and reasons for not killing oneself among community-dwelling young-old Chinese elders." European Psychiatry 28 (January 2013): 1. http://dx.doi.org/10.1016/s0924-9338(13)75800-0.

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27

J Cyriac, Agnes, S. Venkata Raghava, and Kumar Mukund. "Autopsy-Based Study of Suicidal Deaths Among the Elderly Conducted at Victoria Hospital Mortuary." Indian Journal of Forensic Medicine & Toxicology 19, no. 1 (2024): 151–60. https://doi.org/10.37506/5fb9n470.

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Background: Suicide is the act of deliberately killing oneself and it is a significant cause of death in all age groups (1). When comparing the number of attempted and completed suicides, older people have a more significant number of successful suicide than any other age group worldwide (2). 'National Policy on Older Persons'- 1999 defines 'elderly' or ‘senior citizen’ as a person of age 60 years or above (3). NCRB 2020 reported that around 13,126 older people per 100,000 population committed suicide in India (4). Objectives: This study aims to investigate the demographic characteristics, psy
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28

Toma, Sebastian Ionut, Barabas Barna, Daniel Tabian, Calin Scripcaru, Marius Alexandru Moga, and Diana Bulgaru-Iliescu. "Homicidal Act Commited by an Elderly Person With Sexual Dysfunction. Case Report." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 11, no. 3sup1 (2020): 08–19. http://dx.doi.org/10.18662/brain/11.3sup1/117.

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Sexual dysfunctions (SDs) are highly prevalent with aging. Studies reported an interactive correlation between psychiatric morbidity and SD. Also, SDs have significant influence on patients` self-esteem, body image, interpersonal relationships, and physical health in general. The aim of the present research is to present an intimate partner homicide case and to discuss a possible correlation between SDs of elderly patients and their inclination towards aggressive behavior from intimate partner violence (IPV). A forensic psychiatric assessment was performed on a married male patient, aged 61. H
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Ayuning Tyas Azis Putri and Moh. Zeinudin. "Regulasi Penerapan Euthanasia di Indonesia dalam Perspektif Hak Asasi Manusia." Jurnal Hukum dan Sosial Politik 2, no. 3 (2024): 195–209. http://dx.doi.org/10.59581/jhsp-widyakarya.v2i3.3462.

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Humans must go through life events, including babies, children, teenagers, adults, the elderly and death. Death itself is a process that is greatly feared by humans. However, in the development of technology and science in the medical world, death does not come suddenly, death itself can occur with a plan, this action, namely killing in a predictable place and time, is called euthanasia, which is a killing process that is still controversial today. and has not been resolved properly by several parties. The aim of this research is: 1) To identify regulations for implementing euthanasia from a h
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Lee, Eun Young, and Yeon Kyu Jeon. "A Study on the Characteristics and Countermeasures of Killing Crime in Nursing Homicide." Korean Association of Criminal Psychology 18, no. 3 (2022): 81–96. http://dx.doi.org/10.25277/kcpr.2022.18.3.81.

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The improvement in the living standard for the people and the remarkable development of healthcare technology have positive effects of extending our life expectancy and improving the quality of life. However, the extended life expectancy ultimately raises another issue of entrance into a super-aged society. South Korea currently implements a lot of welfare policies, which involve many different types of industrial facilities and leisure life, in preparation for aging society and the number of healthcare institutions, including long-term care centers for the elderly, is on the exponential incre
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Helmi, Rizka, Bintang Yinke Magdalena Sinaga, Parluhutan Siagian, and Putri Eyenoer. "The Comparison of Vitamin C between Pulmonary Tuberculosis and Healthy Control in Medan." Jurnal Respirologi Indonesia 42, no. 3 (2022): 205–8. http://dx.doi.org/10.36497/jri.v42i3.364.

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Background: Pulmonary tuberculosis infection is high burden especially in developed country. Vitamin C is water soluble micronutrient contributes to immune defense by supporting various both of innate and adaptive immunity. Vitamin C protected the host from reactive oxygen and reactive nitrogen intermediates generated during Mycobacterial infection. Patient with pulmonary tuberculosis had lower vitamin C level because the Mycobacterium tuberculosis infection yield to a reactive oxygen species for replication and metabolism and because of the reduced of nutrition intake. Vitamin C as antioxidan
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Mello-Santos, Carolina de, José Manuel Bertolote, and Yuan-Pang Wang. "Epidemiology of suicide in Brazil (1980 - 2000): characterization of age and gender rates of suicide." Revista Brasileira de Psiquiatria 27, no. 2 (2005): 131–34. http://dx.doi.org/10.1590/s1516-44462005000200011.

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OBJECTIVE: To describe the suicide rates in Brazil in recent decades, drawing comparisons with the worldwide epidemiological situation. METHODS: Descriptive analyses of Brazilian suicide data, relating to the 1980-2000 period and extracted from the DATASUS database. Brazilian suicide trends were examined by age and gender. RESULTS: The overall rate of suicide in Brazil increased 21% in 20 years. Men were found to be 2.3 to 4.0 times more likely to commit suicide than were women, and the highest suicide rates were found in the over-65 age group. The greatest increase in suicide rates (1900%) wa
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33

Hysing-Dahl, B. "Geronticide: Killing the Elderly, Mike Brogden Jessica Kingsley Publishers, London, and Philadelphia USA, ISBN 1 85302 709 X, US $23.95." British Journal of Social Work 32, no. 2 (2002): 254–55. http://dx.doi.org/10.1093/bjsw/32.2.254.

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34

Ramírez, Rafael, Noemi Ceprian, Andrea Figuer, et al. "Endothelial Senescence and the Chronic Vascular Diseases: Challenges and Therapeutic Opportunities in Atherosclerosis." Journal of Personalized Medicine 12, no. 2 (2022): 215. http://dx.doi.org/10.3390/jpm12020215.

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Atherosclerosis is probably one of the paradigms of disease linked to aging. Underlying the physiopathology of atherosclerosis are cellular senescence, oxidative stress, and inflammation. These factors are increased in the elderly and from chronic disease patients. Elevated levels of oxidative stress affect cellular function and metabolism, inducing senescence. This senescence modifies the cell phenotype into a senescent secretory phenotype. This phenotype activates immune cells, leading to chronic systemic inflammation. Moreover, due to their secretory phenotype, senescence cells present an i
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35

Piechota, Dariusz. "Vegetarianism on the Vistula River in the Literature at the Turn of the 19th and 20th Centuries." Annales Universitatis Mariae Curie-Sklodowska, sectio N – Educatio Nova 9 (October 24, 2024): 289–306. http://dx.doi.org/10.17951/en.2024.9.289-306.

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The article is devoted to the reception of vegetarianism in Polish literature at the turn of the 19th and 20th centuries. The study recalls the most important popular science publications raising the issues of the vegetarian diet (including the works of Moes-Oskragiełło, Drzewiecki, Jankowski and Jastrzębowski), which are confronted with the literary images of vegetarians (in the works of Reymont, Weyssenhoff, Rodziewiczówna and Mazanowski). The subject of vegetarianism and vegetarians presented in Polish prose evolved over the first decades of the 20th century. Initially, it was identified ma
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36

Boichuk, Sergei, Aigul Galembikova, and David Vollmer. "Enhancement of NK Cell Cytotoxic Activity and Immunoregulatory Effects of a Natural Product Supplement Across a Wide Age Span: A 30-Day In Vivo Human Study." International Journal of Molecular Sciences 26, no. 7 (2025): 2897. https://doi.org/10.3390/ijms26072897.

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The purpose of this study was to examine whether supplementation of ultra- and nanofiltered colostrum-based products, combined with egg yolk extract, nicotinamide mononucleotide (NMN), quercetin, alpha-ketoglutarate, white button mushroom, and celery seed extracts (the formula was patented by 4Life Research Company, USA and named as AgePro), modulate the functional activity of natural killer (NK) cells in vivo. We found that this supplement, taken orally in two capsules twice a day for 30 days, significantly enhanced the cytotoxic activity of NK cells. This was evidenced by the increased NK ce
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37

Rukšėnas, Alfredas. "Annihilation of the Jewish community of Kretinga in summer and autumn 1941." Genocidas ir rezistencija 2, no. 36 (2024): 28–52. http://dx.doi.org/10.61903/gr.2014.202.

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The article examines the annihilation of the Jewish community of Kretinga in summer and autumn 1941. The paper distinguishes two stages of the annihilation. The first stage was isolation of the Jews in the second half of June 1941, when around 340 Jewish men (between 14 and 60 years of age) were arrested in Kretinga Market Square on 24 June and about 540 Jewish women, children and elderly men were arrested between 26 and 27 June. The men were locked up in the synagogue, in the prison or in the police station, which, in addition to their main function, served as temporary concentration camps. J
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Marcelin Vera Octavia, Sri Indaryati, and Novita Elisabeth Daeli. "Penerapan Terapi Rendam Kaki Air Hangat Campur Garam dan Serai Pada Pasien Hipertensi di Panti Werdha Dharma Bhakti Palembang." Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan 2, no. 3 (2024): 59–68. http://dx.doi.org/10.61132/corona.v2i3.556.

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Hypertension is a chronic disease characterized by increased arterial blood pressure. Hypertension cannot be avoided, including in vulnerable groups such as the elderly because as age increases, the risk of hypertension increases so appropriate treatment is needed. Hypertension treatment can be done pharmacologically or non-pharmacologically. Non-pharmacological therapy in this case is foot soak therapy in warm water mixed with salt and lemongrass. The aim of the research is to implement warm water foot soak therapy with salt mixed with lemongrass for hypertensive patients into nursing care. T
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Kemple, Thomas M. "Litigating Illiteracy: The Media, the Law, and The People of the State of New York v. Adelbert Ward." Canadian journal of law and society 10, no. 2 (1995): 73–97. http://dx.doi.org/10.1017/s0829320100004312.

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AbstractMaking sense of the problems which illiterate people face in gaining access to justice puts the foundations of both the ethnography of law and the modern justice system itself into question. The essay explores this thesis with reference to the case of an elderly dairy farmer whose arrest for the mercy killing of his ailing brother attracted intense local and national attention. Documents from the trial which deal with the construction and use of evidence, confession, and testimony, along with schematic representations of the personal, community, and media responses to the case as depic
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40

Sanjay Srivastava and Sakshi Gupta. "A successful Ayurvedic intervention of Pakshaghata (Cerebro-Vascular Stroke) - A Case Report." Journal of Ayurveda and Integrated Medical Sciences 8, no. 7 (2023): 188–92. http://dx.doi.org/10.21760/jaims.8.7.36.

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Pakshaghata (Stroke) is one of the most common causes of death especially in the elderly. Vataja Nanatmaja Vyadhi, Pakshaghata is a Mahavatavyadhi. Pakshaghata has been linked to hemiplegia, a type of paralysis caused by a cerebrovascular accident or stroke. Paksha refers to a man's flank or side, while Ghata, Aghata, and Vadha refer to killing, destruction, and paralysis. Pakshaghata mainly occurs due to the obstruction of cerebral blood vessels, ischemia, and lack of glucose metabolism and weakness of nerve cells. Ayurveda offers various treatment modalities for the management of Pakshaghata
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Kiefer, Jonathan D., Renier Myburgh, Norman F. Russkamp, et al. "A Bispecific Antibody Targeting CD117 and CD3 Enables T Cell Mediated Killing of CD117-Expressing Healthy and Malignant Hematopoietic Cells." Blood 138, Supplement 1 (2021): 2354. http://dx.doi.org/10.1182/blood-2021-147676.

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Abstract INTRODUCTION: Hematopoietic stem and progenitor cells (HSPCs) support life-long hematopoiesis. A single HSPC can also be at the origin of hematological malignancies, such as Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS). Allogeneic HSCT with the intent to eliminate recipient AML or MDS and at the same time replace recipient HSPC with donor-HSPC and immune cells is a life-saving therapeutic option for many patients. However, chemotherapy (and sometimes in addition gamma-irradiation based conditioning regiments) prior to HSCT are associated with substantial toxicity. T
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Dulcamare, Ilaria, Sara Marino, Nunziatina Laura Parrinello, et al. "Dexamethasone and Daratumumab Impair T-Cell Mediated Killing in Multiple Myeloma: Implications for Sequential Therapies." Blood 144, Supplement 1 (2024): 6828. https://doi.org/10.1182/blood-2024-206668.

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Background For elderly patients the combination Daratumumab-lenalidomide-dexamethasone (D-Rd) is an emerging standard-of-care regimen, able to improve long-term outcomes in MM patients. Nevertheless, CD38 is ubiquitously expressed on both MM cells and immune cells, and the effect of daratumumab on MM microenvironment are still under investigation. Thus, we investigated the potential immunomodulatory effect of D-Rd on T-cells function in patients with newly diagnosed MM. Material and methods PB samples were collected from newly diagnosed MM patients receiving D-Rd (n=8) at baseline and after 2
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43

Curti, Antonio, Loredana Ruggeri, Alessandra D'Addio, et al. "Adoptive Immunotherapy with Haploidentical Kir Ligand-Mismatched Natural Killer Cells In Elderly High Risk Acute Myeloid Leukemia Patients: Biological and Clinical Results of A Pilot Study." Blood 116, no. 21 (2010): 4287. http://dx.doi.org/10.1182/blood.v116.21.4287.4287.

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Abstract Abstract 4287 Purpose: To evaluate safety, feasibility and anti-leukemia potential of haploidentical KIR-L mismatched natural killer (NK) cell infusion in elderly high risk acute myeloid leukemia (AML) patients. Patients and Methods: Thirteen patients (5 active disease, 2 molecular relapse and 6 complete remissions) with median age 62 years (range 53–73) received NK cell infusion after immunosuppressive chemotherapy (fludarabine/cyclophosphamide), followed by interleukin-2. Highly purified CD56+CD3- NK cells from haploidentical KIR-L mismatched donors were used. The median number of i
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44

Freese, Peter. "T. C. Boyle’s The Harder They Come: Violence in America." Anglia 135, no. 3 (2017): 511–42. http://dx.doi.org/10.1515/ang-2017-0048.

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AbstractT. C. Boyle’s fifteenth novel The Harder They Come (2015) offers a fictional inquiry into the American propensity for violence and takes its title from Jimmy Cliff’s 1972 reggae song and its motto from D. H. Lawrence’s characterization of the “essential American soul [as] hard, isolate, stoic, and a killer” (1978: 68). The article investigates how Boyle creates a metafictional historiography by combining two unrelated historical events – the bare-handed killing of a mugger by an elderly American veteran in Costa Rica and the long police hunt for the schizophrenic murderer Aaron Bassler
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Oliveira, Barbara F., José Augusto Nogueira-Machado, and Míriam M. Chaves. "The Role of Oxidative Stress in the Aging Process." Scientific World JOURNAL 10 (2010): 1121–28. http://dx.doi.org/10.1100/tsw.2010.94.

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The aging of organisms is characterized by a gradual functional decline of all organ systems. An appropriate theory must explain four main characteristics of aging: it is progressive, endogenous, irreversible, and deleterious for the individual. The aging of the immune system, or immunosenescence, is manifested by an increased susceptibility to infections with increased morbidity and mortality. Phagocytic capacity, synthesis of reactive oxygen intermediaries, and the intracellular killing efficiency of neutrophils are impaired in the elderly. Among all aging theories, the most updated one desc
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46

Dr., Rashmi Jain. "Devi or Demoness: A Journey of Transformation through Bulbbul." Criterion: An International Journal in English 16, no. 2 (2025): 629–39. https://doi.org/10.5281/zenodo.15318264.

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Bulbbul, a movie directed by Anvita Dutt, exhibits the typical patriarchal Renaissance setup. A docile image of a woman was exhibited through Bulbbul, who gets married to an elderly Zamindar -Thakur, as a child. After a lapse of twenty years, circumstances take a mysterious turn and Bulbbul becomes a ‘Thakurain’, with no sign of Thakur in the background. Bulbbul was subjected to violence in a patriarchal system, and she bears it with silence. The joy from her life seems to have vanished. Simultaneously; in the village, mysterious incidents occur where some witch seems to be killing
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47

McNeilly, Hannah, Francis Mutebi, Felix Reichert, et al. "Reduction of tungiasis prevalence, intensity, and morbidity during a two-year long community-based tungiasis control project in a hyperendemic region in Karamoja, Uganda." PLOS Neglected Tropical Diseases 19, no. 6 (2025): e0013149. https://doi.org/10.1371/journal.pntd.0013149.

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Tungiasis is a widespread and debilitating zoonotic Neglected Tropical Disease (NTD). Manual extraction of the sand fleas with non-sterile sharp instruments is the most common but unsafe treatment method in affected communities. Topical application of a dimeticone oil formula (NYDA) has previously been shown to be a safe and effective method of killing embedded sand fleas. The objective of this study was to evaluate a two-year long humanitarian One Health tungiasis control project in 17 villages in Napak district, Karamoja region, Northeastern Uganda. The community-based intervention included
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48

Weston, Victoria J., Angelo Agathanggelou, Paul AH Moss, Pamela R. Kearns, A. Malcolm R Taylor, and Tatjana Stankovic. "ATM Mutant Lymphoid Tumour Cells Exhibit Impaired Activation of the Redox-Sensitive Nrf2-ARE Detoxification Pathway and Are Differentially Sensitive to Nrf2-Activating Compounds." Blood 116, no. 21 (2010): 49. http://dx.doi.org/10.1182/blood.v116.21.49.49.

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Abstract Abstract 49 Inactivation of the tumour suppressor gene, Ataxia Telangiectasia Mutated (ATM), is a frequent event in lymphoid malignancies such as chronic lymphocytic leukaemia (CLL), T-prolymphocytic leukaemia (T-PLL), mantle cell lymphoma (MCL) and, to a lesser degree, T-cell acute lymphoblastic leukaemia (ALL). ATM mutant tumour cells exhibit defective p53-mediated apoptosis following DNA damaging agents in vitro and consequently exhibit poor clinical responses. Multiple pro-survival responses are also altered by ATM dysfunction and may reveal novel approaches for treatment. Our pre
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49

Thambirajoo, Maheswary, Manira Maarof, Yogeswaran Lokanathan, et al. "Potential of Nanoparticles Integrated with Antibacterial Properties in Preventing Biofilm and Antibiotic Resistance." Antibiotics 10, no. 11 (2021): 1338. http://dx.doi.org/10.3390/antibiotics10111338.

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Nanotechnology has become an emerging technology in the medical field and is widely applicable for various clinical applications. The potential use of nanoparticles as antimicrobial agents is greatly explored and taken into consideration as alternative methods to overcome the challenges faced by healthcare workers and patients in preventing infections caused by pathogenic microorganisms. Among microorganisms, bacterial infections remain a major hurdle and are responsible for high morbidity and mortality globally, especially involving those with medical conditions and elderly populations. Over
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Muhammad, Syarifuddin. "MILITER DALAM AL-QUR’AN." Al Burhan: Jurnal Kajian Ilmu dan Pengembangan Budaya Al-Qur'an 20, no. 1 (2020): 98–128. http://dx.doi.org/10.53828/alburhan.v20i1.157.

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This article presents the leadership of Prophet Muhammad PBUH in the field of military that has relevance to the Indonesian National Army as reflected in his actions and behaviors, which are highly spirited, brave and intelligent, militant, strong and skilled and his role model as a perfect individual. In leading the military, Muhammad PBUH prioritized ethics in battles and efforts for self defense. This is different from, example the style of military leadership of Hitler and Genghis Khan who tended to use any means to materialize their ambition to control a region. The perspective of the Qur
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