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Journal articles on the topic 'KILT syndrome'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Van Veen, J., K. K. Hampton, and M. Makris. "Kilt Syndrome?" British Journal of Haematology 118, no. 4 (2002): 1199–200. http://dx.doi.org/10.1046/j.1365-2141.2002.370311.x.

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2

Sumin Toms, Ann, and David Wotherspoon. "P.184 Management of a Pregnant woman with KILT syndrome." International Journal of Obstetric Anesthesia 62 (May 2025): 104562. https://doi.org/10.1016/j.ijoa.2025.104562.

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3

Rughani, Prita, Frances Yeung, Camilla Raya Halgren, Michaela Cada, and Sarah Schwartz. "Kidney and inferior vena cava abnormalities with leg thromboses (KILT) syndrome: A case report and literature review." Paediatrics & Child Health 25, no. 5 (2019): 273–75. http://dx.doi.org/10.1093/pch/pxy170.

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Abstract Venous thromboembolism (VTE) is now increasingly recognized within paediatrics. A Canadian VTE registry has estimated the incidence as 0.7 to 1.0 per 100,000 population, with a peak in infancy and adolescence. Congenital inferior vena cava agenesis (IVCA) is an important risk factor that may be unfamiliar to paediatricians. Several case reports have since described an association between IVCA, VTE, and renal hypoplasia, which has been referred to as KILT syndrome (Kidney and IVC abnormalities with Leg Thromboses). We describe the first reported paediatric case of KILT syndrome in Cana

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4

International, Journal of Medical Science and Innovative Research (IJMSIR). "A Case Report on KILT Syndrome (Kidney and Inferior Vena Cava Abnormalities with Legthrombosis) in A Young Male." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 4 (2024): 21–26. https://doi.org/10.5281/zenodo.15424190.

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<strong>Abstract</strong> First discovered in 2002, KILT syndrome is an extremely unusual trio consisting of kidney abnormalities, inferior vena cava (IVC) malformations, and deep vein thrombosis (DVT). This disorder, which is more common in younger people, is linked to an increased risk of recurrent thrombotic episodes and typically manifests itself accidentally during imaging. Additionally, it's important to closely observe any signs of possible renal problems.We present the case of a 20-year-old male patient who complained of right flank pain and right lower limb discomfort that had persist

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5

Pomeranz, Christy B., Danielle L. Cullen, and Richard D. Bellah. "Deep venous thrombosis in a child with inferior vena cava and renal anomalies: KILT syndrome." Pediatric Radiology 48, no. 10 (2018): 1521–25. http://dx.doi.org/10.1007/s00247-018-4155-3.

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6

Moragón-Ledesma, Sergio, Francisco Galeano-Valle, Enrique Calleja-Cartón, Jorge Del-Toro-Cervera, and Pablo Demelo-Rodríguez. "Bilateral Deep Vein Thrombosis, Vena Cava Agenesis, and Renal Abnormalities: KILT Syndrome—A Case Report and Literature Review." Journal of Cardiovascular Translational Research 13, no. 4 (2019): 629–31. http://dx.doi.org/10.1007/s12265-019-09935-9.

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7

Chin, LHQ, M. Cheung, GHT Ng, and WWM Lam. "Kidney and Inferior Vena Cava Abnormalities with Leg Thrombosis (KILT Syndrome) in a Young Healthy Male: a Case Report." Hong Kong Journal of Radiology 24, no. 3 (2021): 208–12. http://dx.doi.org/10.12809/hkjr2117261.

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8

Hearn, Amy, and Smita Gunda. "Congenital Single Kidney, Inferior Vena Cava Abnormality, and Bilateral Ileo-Femoral Deep Vein Thrombosis: A Case of KILT Syndrome." Journal of the American Society of Nephrology 34, no. 11S (2023): 236–37. http://dx.doi.org/10.1681/asn.20233411s1236c.

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9

Fung, James Kiujing, Victor Hip Wo Yeung, Sau Kwan Chu, and Chi Wan Man. "KILT (Kidney and IVC Abnormalities with Leg Thrombosis) Syndrome in a 41-Years-Old Man with Loin Pain and Fever." Urology Case Reports 12 (May 2017): 6–8. http://dx.doi.org/10.1016/j.eucr.2017.01.003.

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10

Fior, Davide, Matteo Pileri, Antonio Rovere, et al. "Endovascular management of KILT syndrome and COVID-19-related extensive deep vein thrombosis in a pregnant patient: A case report." Radiology Case Reports 19, no. 6 (2024): 2277–81. http://dx.doi.org/10.1016/j.radcr.2024.02.113.

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11

Pantic, Nikola, Mirjana Cvetkovic, Jelena Milin-Lazovic, et al. "P1655: DEEP VENOUS THROMBOSIS IN PATIENT WITH ATRESIA OF INFERIOR VENA CAVA AND RIGHT KIDNEY HYPOPLASIA (KILT SYNDROME): CASE REPORT AND SYSTEMATIC REVIEW OF THE LITERATURE." HemaSphere 7 (August 2023): e0100103. http://dx.doi.org/10.1097/01.hs9.0000973492.01001.03.

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12

Bami, Sakshi, Yarelis Vazquez, Valeriy Chorny, Rachelle Goldfisher, and John Amodio. "Deep Venous Thrombosis of the Leg, Associated with Agenesis of the Infrarenal Inferior Vena Cava and Hypoplastic Left Kidney (KILT Syndrome) in a 14-Year-Old Child." Case Reports in Pediatrics 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/864047.

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Agenesis of the inferior vena cava (IVC) is a rare anomaly which can be identified as incidental finding or can be associated with iliofemoral vein thrombosis. IVC agenesis has a known association with renal anomalies which are mainly confined to the right kidney. We describe a case of a 14-year-old male who presented with left leg swelling and pain. Ultrasonography confirmed the presence of left leg deep vein thrombosis (DVT). No underlying hematologic risk factors were identified. A CT scan was obtained which demonstrated absent infrarenal IVC and extensive thrombosis in the left deep venous

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13

Vahabzadeh, Ali, and Beverton Moxey. "Overeating Can Kill You: The Boerhaave Syndrome." Southern Medical Journal 98, Supplement (2005): S53—S54. http://dx.doi.org/10.1097/00007611-200510001-00147.

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14

Russell, Brenda L., and Linda S. Melillo. "Attitudes Toward Battered Women Who Kill." Criminal Justice and Behavior 33, no. 2 (2006): 219–41. http://dx.doi.org/10.1177/0093854805284412.

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Battered woman’s syndrome has become highly controversial, particularly when used as a defense in cases of homicide. According to legal scholars and social scientists, the characteristics associated with the syndrome constitute a standard that jurors use to evaluate battered women. This study evaluated the hypothesis that jurors use prototypical standards of battered women to reach conclusions about defendants in these cases. Results supported the hypotheses that verdicts are directly influenced by typicality and response history (passive vs. active) of the defendant. Defendants portrayed as a

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15

Quintão, Éder C. "Metabolic syndrome: did the creator kill the creature?" Arquivos Brasileiros de Endocrinologia & Metabologia 55, no. 5 (2011): 355–56. http://dx.doi.org/10.1590/s0004-27302011000500011.

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16

James, Stacy H. "Clots Kill: Hematologic Pharmacology for ST-Segment Elevation Myocardial Infarction." Critical Care Nurse 32, no. 6 (2012): 35–41. http://dx.doi.org/10.4037/ccn2012104.

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Drugs that work on the hematologic system play an important role in helping to limit the morbidity and mortality that can be associated with an acute coronary syndrome. The pharmacology of the fibrinolytic agents, thrombin inhibitors, and antiplatelet agents is described. A case study of a woman having an ST-segment elevation myocardial infarction is reviewed to highlight the importance of drugs that work on the hematologic system.

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17

Criddle, David N. "How does Alcohol Kill Cells?" European Review 18, no. 1 (2010): 57–72. http://dx.doi.org/10.1017/s1062798709990135.

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Excessive alcohol consumption is linked to a variety of major health problems, including the severe inflammation of the pancreas, which may lead to premature death of the individual.1 Hospital admissions in the United Kingdom due to acute pancreatitis were recently shown to have doubled over a 30 year period,2 in parallel with an estimated doubling of alcohol consumption in this country, and the incidence of the disease is dramatically increasing. Within the European Union, acute pancreatitis may attain an incidence of up to 1 per 1000 individuals per year. In accord with trends in drinking li

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18

Ulusoy, Seçkin, Nurdoğan Yavuz, Mehmet Emre Dinç, and Mustafa Acar. "Can the devices used to treat obstructive sleep apnoea syndrome increase the tendency to gain weight?" ENT Updates 5, no. 3 (2015): 113–18. http://dx.doi.org/10.2399/jmu.2015003010.

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19

Ho, Robert Tack Kwei, and Natalie Chantagul. "An exploration of Thai public perceptions of defenses in cases of women who kill their domestically violent spouses." Australian & New Zealand Journal of Criminology 50, no. 4 (2016): 602–22. http://dx.doi.org/10.1177/0004865816668222.

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The present study investigated the issue of domestic violence in Thailand and in particular the reactions of the Thai populace (male versus female) to a battered woman who killed her abusive spouse, as well as how such reactions could be influenced by the presentation of expert testimony related to the battered woman syndrome. Cluster sampling conducted within the Bangkok metropolitan area in Thailand yielded a sample of 1190 participants who voluntarily filled in the study’s questionnaire. Multi-group path analysis showed no significant gender difference in the direct influence of battered wo

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20

Lo, Bernice, Alejandro Schäffer, Daniel Paik, et al. "Identifying modifier genes in Autoimmune Lymphoproliferative Syndrome (P4084)." Journal of Immunology 190, no. 1_Supplement (2013): 51.8. http://dx.doi.org/10.4049/jimmunol.190.supp.51.8.

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Abstract Autoimmune Lymphoproliferative Syndrome (ALPS) is an inherited disorder of defective lymphocyte apoptosis, characterized by chronic lymphadenopathy and/or splenomegaly, autoimmune cytopenias, and the expansion of a unique population of CD4-CD8- α/β T cells. ALPS is predominately caused by mutations in Fas with incomplete penetrance. In order to identify modifier genes and understand the mechanism of incomplete penetrance of disease in ALPS, we performed a linkage study using five large families with multiple ALPS patients and healthy Fas mutation-positive relatives (HMPRs) in each fam

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21

McPherson, Rachel. "Battered Woman Syndrome, Diminished Responsibility and Women Who Kill: Insights from Scottish Case Law." Journal of Criminal Law 83, no. 5 (2019): 381–93. http://dx.doi.org/10.1177/0022018319858506.

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Using Scotland as a case study, this article maps the development of Battered Woman Syndrome in law. It looks to the potential space for development that has been created by the recent case of Graham v HM Advocate, concluding that such a more would be an important step and one with significant implications for domestic abuse policy and the treatment of female accused more widely.

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22

Acartürk, Tahsin, Mohamed Abdel-Motleb, and Firat Acar. "How to Kill a Flap: Munchausen Syndrome — A Silent Trap for Plastic Surgeons." Journal of Hand and Microsurgery 06, no. 01 (2016): 42–44. http://dx.doi.org/10.1007/s12593-012-0088-5.

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23

Ji, Xiaoyun, Ying Wu, Junpeng Yan, et al. "Kill HIV by Starvation–Mechanism of Allosteric Activation of SAMHD1." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C121. http://dx.doi.org/10.1107/s2053273314098787.

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SAMHD1, a deoxyribonucleoside triphosphate triphosphohydrolase (dNTPase), prevents the infection of blood cells by retroviruses, including HIV, by depleting the cellular dNTP pool available for viral reverse transcription. SAMHD1 is a major regulator of cellular dNTP levels in mammalian cells. Mutations in SAMHD1 are associated with the autoimmune condition Aicardi Goutières Syndrome (AGS), whose clinical manifestations resemble congenital viral infection. The catalytic activity of SAMHD1 is regulated by allosteric binding of dGTP, which enables SAMHD1 monomers/dimers to assemble into the cata

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24

Gutasan, Norleena, Rojiah Saiwah Karim, Zoriffah Mohd Kudin, and Nor Jannah Hassan. "LEXSSA KIT IMPROVE READING SKILLS FOR STUDENT WITH DISABILITIES." International Journal of Modern Education 3, no. 8 (2021): 149–66. http://dx.doi.org/10.35631/ijmoe.380013.

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The LEXSSA Kit (More Effective Xtra Fun Suitable for Student Levels) is produced for Students with Learning Disabilities. The aim of this research is to help students with Learning Disabilities such as students with Autism, Dyslexia, Slow Learner, Down Syndrome, and Attention Deficit Hyperactive Disorder (ADHD) improve their reading skills. This study was conducted to observe the perception of Students with Learning Disabilities of using LEXSSA Kit as learning aids that can encourage active learning and improve the mastery of reading. The design of this research has used a survey method and pr

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25

ZİNCİR ERÇİN, Dilek Özge, and Aysun ÖZLÜ. "Kalça ve Diz Osteoartritli Hastalarda Huzursuz Bacak Sendromunun Yaygınlığı ve Şiddeti." Journal of Contemporary Medicine 12, no. 5 (2022): 631–35. http://dx.doi.org/10.16899/jcm.1166260.

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Amaç: Huzursuz bacak sendromunun (HBS) prevalansı, şiddeti, ağrı düzeyleri, uyku hijyeni ve yaşam kalitesinin kalça ve diz osteoartriti (OA) arasında farklılık gösterip göstermediğini araştırmak. Gereç ve Yöntem: 2 Ocak 2020 - 2 Haziran 2020 tarihleri arasında 55-75 yaşları arasında diz OA'sı olan 103 ve kalça OA'si olan 98 hasta dahil edilme ve dışlama kriterlerine göre kaydedildi. Ağrı şiddeti için visüel ağrı skalası (VAS), OA şiddeti için Lequesne şiddet indeksi, HBS semptomlarının sıklığı ve şiddeti ve uyku davranışları için Uyku Hijyeni İndeksi ve genel sağlığın değerlendirilmesi i

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26

Micalizzi, Emma W., and Myron L. Smith. "Volatile organic compounds kill the white-nose syndrome fungus, Pseudogymnoascus destructans, in hibernaculum sediment." Canadian Journal of Microbiology 66, no. 10 (2020): 593–99. http://dx.doi.org/10.1139/cjm-2020-0071.

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Pseudogymnoascus destructans, the fungal pathogen that causes white-nose syndrome, has killed millions of bats across eastern North America and continues to threaten new bat populations. The spread and persistence of P. destructans has likely been worsened by the ability of this fungus to grow as a saprotroph in the hibernaculum environment. Reducing the environmental growth of P. destructans may improve bat survival. Volatile organic compounds (VOCs) are attractive candidates to target environmental P. destructans, as they can permeate through textured environments that may be difficult to th

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27

Ward, Louisa. "Michael Kohlhaas Syndrome – Taking the court to court." BJPsych Open 7, S1 (2021): S121—S122. http://dx.doi.org/10.1192/bjo.2021.353.

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ObjectiveTo explore Michael Kohlhaas syndrome and development of litigious paranoia.Case reportA 50-year-old Swiss woman spent a number of weeks travelling around the UK, reporting to police that her family in Switzerland were working with their police, doctors and the mafia to kill her. She was therefore running away for her own safety, and trying to seek legal help to investigate. She had been in close contact with a woman in London who claimed to be able to give her legal aid in exchange for payment. On admission to the ward, it was felt that the legal aid was actually feeding her persecuto

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28

Yalçin, Fatih, Maria Roselle Abraham, and Mario J. Garcia. "Stress and Heart in Remodeling Process: Multiple Stressors at the Same Time Kill." Journal of Clinical Medicine 13, no. 9 (2024): 2597. http://dx.doi.org/10.3390/jcm13092597.

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Myocardial remodeling is developed by increased stress in acute or chronic pathophysiologies. Stressed heart morphology (SHM) is a new description representing basal septal hypertrophy (BSH) caused by emotional stress and chronic stress due to increased afterload in hypertension. Acute stress cardiomyopathy (ASC) and hypertension could be together in clinical practice. Therefore, there are some geometric and functional aspects regarding this specific location, septal base under acute and chronic stress stimuli. The findings by our and the other research groups support that hypertension-mediate

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Basnet, Anjila, Pragya Basnet, Poojyashree Karki, and Shriraj Shrestha. "Computer Vision Syndrome Prevalence and Associated Factors Among the Medical Student in Kist Medical College." Nepalese Medical Journal 1, no. 1 (2018): 29–31. http://dx.doi.org/10.3126/nmj.v1i1.20396.

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Introduction: Computers and other visual display terminals are now an essential part of our daily life. In the present era, use of computer has increased many folds, and its use has been associated with increased health risks, especially eyes.Materials and Methods: This hospital-based prospective, observational, descriptive study. “Specific Computer Users Questionnaire’’regarding the visual symptoms was put used. Schirmer’s test –I, and Tear film break up time were evaluated in all students.Results: Among 100 medical students 74% of the medical students sampled who used to spend 2 hours or mor

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30

Arun, Tyagi, Jadhav Sagar, Waghmare Manoj, AK Srivastava, and AB Khare. "Bagassosis, rare cause of hypersensitivity pneumonitis: A case report." Iberoamerican Journal of Medicine 2, no. 4 (2020): 381–84. http://dx.doi.org/10.53986/ibjm.2020.0064.

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Hypersensitivity pneumonitis (HP), also called extrinsic allergic alveolitis, is a respiratory syndrome involving the lung parenchyma specifically the alveoli, terminal bronchioles and alveolar interstitium. HP is caused by delayed allergic reaction to variety of antigens like microbes, animal proteins, and low-molecular-weight chemicals. Bagassosis is one such HP caused by repetitive inhalation of bagasse. Though use of bagasse as cause of HP is known, use of bagasse in brick- kiln factory as fuel and its association with HP has not been well documented. We report a case of HP in a brick-kiln

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31

Cimmino, Giovanni, Adriano Caputo, Paolo Golino, Francesco Natale, and Francesco S. Loffredo. "Isolated Common Iliac Aneurysm and Dilated Left Ventricle: Kill Two Birds with One Stone?" Journal of Cardiovascular Echography 35, no. 1 (2025): 55–57. https://doi.org/10.4103/jcecho.jcecho_52_24.

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Strongyloides stercoralis is a nematode commonly known as roundworm. Humans are the primary host for the parasite and are infected when bare skin is exposed to contaminated soil. Once in the skin of the human host, the larvae migrate to the heart through the blood and then to the alveoli of the lungs, subsequently ending up in the trachea where the larvae are coughed up and swallowed. Clinically, this infection may be asymptomatic as well as present as an acute or chronic gastrointestinal discomfort, hyperinfection syndrome, or disseminated disease with the involvement of different organs. Myo

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32

TICARĂU, Adriana, and Dumitru MATEI. "Endothelial dysfunction assessment in healthy smokers." Romanian Journal of Medical Practice 11, no. 2 (2016): 147–50. http://dx.doi.org/10.37897/rjmp.2016.2.8.

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Smoking is a known risk factor for cardiovascular disease, chronic respiratory neoplasms and diseases, and will kill more than one billion people this century, according to the World Health Organization. Smoking induced endothelial dysfunction triggers a new alarm for this social custom, which in connection with metabolic syndrome, who has reached alarming rates of prevalence in recent years, contributes specifically to cardiovascular morbidity and mortality. In this study we aimed to evaluate more parameters of endothelial dysfunction in smokers patients, indicating a high statistical signifi

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33

Medarametla, Keerthana. "Battered Women: The Gendered Notion of Defences Available." Socio-Legal Review 17, no. 2 (2017): 108. http://dx.doi.org/10.55496/jekg1269.

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Battered Women Syndrome is a psychological theory propounded by Dr. Lenore Walker that explains why battered women who are compelled to kill their partners continued to stay in the relationship in the first place. While focusing on the evolution of the Battered Women Syndrome in other countries, especially United Kingdom; this paper studies the interpretation of the corresponding ‘Nallathangal Syndrome’ as applied in the Indian context. However, the legal recognition of the Battered Women Syndrome is at its nascent stage in India. While a lot is written in India about the shortcomings of the P

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34

Maria, Khatoon, Maru Prakhar, and Singh Vandini. "Comparative Study of Serum Calcium and PTH (Parathyroid Hormones) In Pre-Menopausal and Post-Menopausal Women of Madhya Pradesh." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 608–11. https://doi.org/10.5281/zenodo.11099340.

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<strong>Background: </strong>Apart from menopause, there are many factors that cause osteoporosis, i.e., adverse effects of drug therapy, endocrine disorders, eating disorders, immobilization, marrow-related disorders, GIT, biliary tract or renal disorders, and cancer; hence, the exact cause of osteoporosis has to be ruled out. <strong>Method:</strong> 25 premenopausal and 25 postmenopausal women were studied. Apart from their anthropological parameters, their biochemical profile was studied. 5 ml of venous blood from each patient was collected. Serum calcium was measured by the

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35

Lagunathan, Sharmilaa. "Battered woman syndrome and PTSD in women who kill their abusing partner: a study in medical jurisprudence." BJPsych Open 7, S1 (2021): S266. http://dx.doi.org/10.1192/bjo.2021.708.

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AimsThe aim of the study was to identify any symptoms or features of Battered Woman Syndrome (BWS) or Post-traumatic Stress Disorder (PTSD) that may be associated with, or explain, abused women killing their abuser; and the extent to which such identified symptoms or features have been deemed, or are potentially relevant, to past and now reformed partial defences to murder in English law. Hence two sub-studies were completed.MethodThe first sub-study identified mental symptoms of BWS or PTSD apparent in battered women who kill their abuser; achieved by identifying relevant research papers, thr

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36

Hennig, Christian, Christine Happle, and Gesine Hansen. "“A bad wound may heal, but a bad name can kill”—lessons learned from “hyper-IgM syndrome”." Journal of Allergy and Clinical Immunology 128, no. 6 (2011): 1380–82. http://dx.doi.org/10.1016/j.jaci.2011.07.041.

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37

Deeg, H. Joachim. "Hematopoietic Cell Transplantation for Myelodysplastic Syndrome." American Society of Clinical Oncology Educational Book, no. 35 (May 2015): e375-e380. http://dx.doi.org/10.14694/edbook_am.2015.35.e375.

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Although high-dose chemotherapy may cure a small subset of patients with myelodysplastic syndrome (MDS), allogeneic hematopoietic cell transplantation (HCT) is the only currently available modality that is curative in a large proportion of patients. Approximately 30% to 40% of patients with high-risk MDS and 60% to 80% of patients with low-risk MDS survive long-term in remission. Disease classification and risk assessment schemes, such as the World Health Organization (WHO) Prognostic Scoring System (WPSS), the Revised International Prognostic Scoring System (IPSS-R), and patient characteristi

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38

Tyagi, Arun, Sagar Jadhav, Manoj Waghmare, AK Srivastava, and AB Khare. "Bagassosis, rare cause of hypersensitivity pneumonitis: A case report." Iberoamerican Journal of Medicine 2, no. 4 (2020): 381–84. https://doi.org/10.5281/zenodo.3834307.

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Hypersensitivity pneumonitis (HP), also called extrinsic allergic alveolitis, is a respiratory syndrome involving the lung parenchyma specifically the alveoli, terminal bronchioles and alveolar interstitium. HP is caused by delayed allergic reaction to variety of antigens like microbes, animal proteins, and low-molecularweight chemicals. Bagassosis is one such HP caused by repetitive inhalation of bagasse. Though use of bagasse as cause of HP is known, use of bagasse in brickkiln factory as fuel and its association with HP has not been well documented. We report a case of HP in a brick-kiln wo

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39

Deb, A. "Battered Woman Syndrome: Prospect of Situating It Within Criminal Law in India." BRICS Law Journal 8, no. 4 (2021): 103–35. http://dx.doi.org/10.21684/2412-2343-2021-8-4-103-135.

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In patriarchal cultures, like the one prevalent in India, rigid, polarised and hierarchical gender roles work to establish a strong normative relationship between gender and the treatment of offenders committing violent crimes such as homicide. While most of the common law countries have already undergone a social change towards making their criminal laws more gender-sensitive by accommodating the experiences of battered women, the situation in India is quite different. Indian courts have recognised Battered Woman Syndrome very recently in only three cases, much differently than courts in othe

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40

Bernier, Joanne, and André Cellard. "Le syndrome de la femme fatale : « Matricide » et représentation féminine au Québec, 1898-1940." Criminologie 29, no. 2 (2005): 29–48. http://dx.doi.org/10.7202/017388ar.

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Between 1867 and 1976, when the death penalty was abolished in Canada, sixteen women faced the death penalty in Québec for their crime. Five of them found guilty for murdering their husband. In a period where women had a specific role of spouse and mother, the murder of the husband was seen as the worst crime possible because it was seen as a transgression of their roles as women, wife and mother. This article examines the discourses of the judges and prosecutors in the trials of Québec women accused of killing their husbands. The authors tried to find common themes between these trials and cl

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Shi, Zoe W., Yanli Chen, Krystal M. Ogoke, Ashley B. Strickland, and Meiqing Shi. "Cryptococcal Immune Reconstitution Inflammatory Syndrome: From Clinical Studies to Animal Experiments." Microorganisms 10, no. 12 (2022): 2419. http://dx.doi.org/10.3390/microorganisms10122419.

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Cryptococcus neoformans is an encapsulated pathogenic fungus that initially infects the lung but can migrate to the central nervous system (CNS), resulting in meningoencephalitis. The organism causes the CNS infection primarily in immunocompromised individuals including HIV/AIDS patients, but also, rarely, in immunocompetent individuals. In HIV/AIDS patients, limited inflammation in the CNS, due to impaired cellular immunity, cannot efficiently clear a C. neoformans infection. Antiretroviral therapy (ART) can rapidly restore cellular immunity in HIV/AIDS patients. Paradoxically, ART induces an

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42

Matsuda, Kouki, and Kenji Maeda. "HIV Reservoirs and Treatment Strategies toward Curing HIV Infection." International Journal of Molecular Sciences 25, no. 5 (2024): 2621. http://dx.doi.org/10.3390/ijms25052621.

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Combination antiretroviral therapy (cART) has significantly improved the prognosis of individuals living with human immunodeficiency virus (HIV). Acquired immunodeficiency syndrome has transformed from a fatal disease to a treatable chronic infection. Currently, effective and safe anti-HIV drugs are available. Although cART can reduce viral production in the body of the patient to below the detection limit, it cannot eliminate the HIV provirus integrated into the host cell genome; hence, the virus will be produced again after cART discontinuation. Therefore, research into a cure (or remission)

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De Weerdt, Annick, Annemie Snoeckx, Paul Germonpré, and Philippe G. Jorens. "Rapid-Onset Adult Respiratory Distress Syndrome after Activated Charcoal Aspiration. A Pitch-Black Tale of a Potential to Kill." American Journal of Respiratory and Critical Care Medicine 191, no. 3 (2015): 344–45. http://dx.doi.org/10.1164/rccm.201409-1607im.

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Higueras, T. Gutiérrez, S. Sainz De La Cuesta Alonso, F. Calera Cortés, and S. Vicent Forés. "Vascular psychosis in the elderly. case report and literature review for different antypsichotic treatment strategies." European Psychiatry 64, S1 (2021): S744—S745. http://dx.doi.org/10.1192/j.eurpsy.2021.1973.

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IntroductionThe most common cause of vascular psychosis is cerebrovascular disease. Tipically a late-onset in the elderly is accompanied with multiple strokes (disruption of blood flow to the brain). Dementia is a clinical syndrome characterised by cognitive, neuropsychiatric, and functional symptoms. About neuropsychiatric symptoms there are multiple warnings concerning the use of antipsychotics in people with dementia due to an increased risk of death and stroke.ObjectivesPresentation of a case of vascular psychosis with a literature review of antipsychotic drugs used in these cases.MethodsW

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Montisci, Andrea, Maria Teresa Vietri, Vittorio Palmieri, Silvia Sala, Francesco Donatelli, and Claudio Napoli. "Cardiac Toxicity Associated with Cancer Immunotherapy and Biological Drugs." Cancers 13, no. 19 (2021): 4797. http://dx.doi.org/10.3390/cancers13194797.

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Cancer immunotherapy significantly contributed to an improvement in the prognosis of cancer patients. Immunotherapy, including human epidermal growth factor receptor 2 (HER2)-targeted therapies, immune checkpoint inhibitors (ICI), and chimeric antigen receptor-modified T (CAR-T), share the characteristic to exploit the capabilities of the immune system to kill cancerous cells. Trastuzumab is a monoclonal antibody against HER2 that prevents HER2-mediated signaling; it is administered mainly in HER2-positive cancers, such as breast, colorectal, biliary tract, and non-small-cell lung cancers. Imm

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Dick, Jenna K., Venkat Krishna, Aaron Khaimraj, et al. "355 Unraveling and targeting the innate immune response in Multisystem Inflammatory Syndrome in Children (MIS-C)." Journal of Clinical and Translational Science 7, s1 (2023): 105. http://dx.doi.org/10.1017/cts.2023.395.

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OBJECTIVES/GOALS: The innate immune responses to Multisystem Inflammatory Syndrome in Children (MIS-C) are not fully known. Using samples from MIS-C, we will assess the cellular responses and develop a novel Tri-Specific Killer Engager (TRiKE) that engages innate immune cells to improve those responses. METHODS/STUDY POPULATION: We collected blood samples from 60 pediatric patients from which we isolated plasma and peripheral blood mononuclear cells. We received blood samples from 13 MIS-C, 32 severe acute COVID, 5 COVID-19 asymptomatic, and 15 COVID-19 negative patients. Using plasma, we then

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Cluzeau, Thomas, Nathan Furstoss, Coline Savy, et al. "Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia." International Journal of Molecular Sciences 21, no. 1 (2019): 164. http://dx.doi.org/10.3390/ijms21010164.

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Myelodysplastic syndrome (MDS) defines a group of heterogeneous hematologic malignancies that often progresses to acute myeloid leukemia (AML). The leading treatment for high-risk MDS patients is azacitidine (Aza, Vidaza®), but a significant proportion of patients are refractory and all patients eventually relapse after an undefined time period. Therefore, new therapies for MDS are urgently needed. We present here evidence that acadesine (Aca, Acadra®), a nucleoside analog exerts potent anti-leukemic effects in both Aza-sensitive (OCI-M2S) and resistant (OCI-M2R) MDS/AML cell lines in vitro. A

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Hidayat, Rachmat, and Patricia Wulandari. "The Role of CD4+ and CD8+ T Cells in COVID-19 (Corona Virus Disease 2019)." Archives of The Medicine and Case Reports 4, no. 1 (2022): 331–35. http://dx.doi.org/10.37275/amcr.v4i1.244.

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The SARS-CoV-2 virus mainly acts on lymphocytes, especially CD4+ and CD8+ T cells, Analysis of a subset of lymphocytes may help in screening awal critical course of the disease. Pincrease of proinflammatory cytokines and chemokines, and decreased regulatory/regulatory T cells contribute to an excessive inflammatory response (increased cytokine production, cytokine release syndrome) with loss of control over the damaging immune response and increased tissue damage (e.g. in the lungs). Sometimes the body's response to infection becomes very exaggerated. for example, when SARS-CoV-2 enters the lu

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Gautam, Ashima. "Antimicrobial Resistance: The Next Probable Pandemic." Journal of Nepal Medical Association 60, no. 246 (2022): 225–28. http://dx.doi.org/10.31729/jnma.7174.

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As the world still mourns the victims of the pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2, another pandemic that is expected to kill millions of people in less than a century, is already brewing. In the distant future, the global, mostly silent pandemic of antimicrobial resistance is increasingly claiming the lives of patients on hospital floors. Unfortunately, the global health community is now gradually and progressively facing the silently emerging pandemic that could endanger some of the most significant advances in modern medicine. Medical students as future physicia

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Black, C. M., L. E. Bermudez, L. S. Young, and J. S. Remington. "Co-infection of macrophages modulates interferon gamma and tumor necrosis factor-induced activation against intracellular pathogens." Journal of Experimental Medicine 172, no. 3 (1990): 977–80. http://dx.doi.org/10.1084/jem.172.3.977.

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Co-infection of macrophages (M phi) with Toxoplasma gondii and Mycobacterium avium-intracellulare complex (MAC) has been observed in patients with acquired immunodeficiency syndrome (AIDS). In this study we have demonstrated that co-infected murine M phi respond differently to cytokine stimulation than M phi infected with either of the microorganisms alone. Whereas treatment with interferon gamma (IFN-gamma) activated both single and co-infected groups of M phi to kill T. gondii, treatment with TNF did not influence the rate of MAC growth in co-infected M phi, in contrast with the inhibition o

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