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Relevant bibliographies by topics / Knee osteoarthritis

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Academic literature on the topic 'Knee osteoarthritis'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 June 2025

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Journal articles on the topic "Knee osteoarthritis"

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Alvarez López, Alejandro. "Lateral Knee Osteoarthritis." Clinical Orthopaedics and Trauma Care 4, no. 1 (2022): 01–05. http://dx.doi.org/10.31579/2694-0248/017.

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Background: gonarthrosis is a common entity characterized by involvement of one or more compartments, of which the lateral one is the one with the lowest incidence in isolation. Aim: the aims of this research are too updated on the most important features on lateral knee osteoarthritis and look for updated bibliography on the subject. Methods: PubMed, Hinari, SciELO and Medline databases were searched for citations from August 1st 2021 to September 30th 2021 using the EndNote search manager and reference manager. Out of 312 articles, 44 selected citations were used in this review, being 42 of the last five years. Results: the main causes of lateral knee osteoarthritis are mentioned, especially the secondary ones. Reference is made to the main clinical and imaging elements for diagnosis based on plain radiography and magnetic resonance imaging. Both conservative and surgical treatment modalities are exposed, in the latter the main indications and complications are described, among which osteotomies and arthroplasties stand out. Conclusions: lateral gonarthrosis is the least common of the unicompartmental gonarthrosis that affect the knee joint. Clinical and imaging diagnosis provides the essential elements for both conservative and surgical therapeutic behaviour, the latter modality includes techniques that preserve the joint such as osteotomies and others that do not, such as arthroplasties.

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Fahlman, Lissa, Emmeline Sangeorzan, Nimisha Chheda, and Daphne Lambright. "Older Adults without Radiographic Knee Osteoarthritis: Knee Alignment and Knee Range of Motion." Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders 7 (January 2014): CMAMD.S13009. http://dx.doi.org/10.4137/cmamd.s13009.

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This study describes knee alignment and active knee range of motion (ROM) in a community-based group of 78-year old adults (n = 143) who did not have radiographic evidence of knee osteoarthritis in either knee (KL < 2). Although knee malalignment is a risk factor for knee osteoarthritis, most women and men had either valgus or varus alignments. Notably, no men were valgus in both knees. Women with both knees valgus had significantly greater body mass index ( P > 0.001) than women with varus or straight knees. Men and women with valgus or varus knee alignments had generally lower ROM than individuals with both knees straight. In summary, this study highlights the complex relationships among knee alignment, ROM, body mass index, and gender in elderly adults without radiographic knee osteoarthritis.

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Brigham, Christopher R., Charles N. Brooks, and James B. Talmage. "Knee Osteoarthritis." Guides Newsletter 10, no. 2 (2005): 1–3. http://dx.doi.org/10.1001/amaguidesnewsletters.2005.marapr01.

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Abstract More than 20 million Americans have osteoarthritis (OA), which affects the knee more often than any other joint and is the most common cause of long-term disability in persons older than 65 years. Knee OA is common, particularly in older patients and especially the obese. Knee injury, depending on the severity and type, can increase the risk of developing and the rate of progression of OA. In assessing impairment for knee OA, the evaluator must obtain a thorough history and physical examination and identify all potential risk factors. To opine that an injury caused OA, the evaluator should demonstrate that the traumatized knee shows significant arthritis but that the contralateral uninjured knee is radiographically normal; for an evaluator to suggest that pre-existing arthritis was aggravated, the involved knee should show significantly more advanced OA than the contralateral joint. Joint space widths (cartilage intervals) of both knees must be measured carefully on anteroposterior films obtained standing with a film-to-camera distance of 90 cm (36 in) and the beam at the level of and parallel to the joint surface. Taking into account all of the data (history, physical findings, and radiographic measurements from both the involved and contralateral joint), the rating physician can assess causation, estimate impairment, and apportion the latter to one or more etiologies.

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Phalswal, Uma, Vandna Pandey, Ashok Kumar, and Abhay Elhence. "Correlation of knee society score and oxford knee score in patients with moderate to severe osteoarthritis of the knee." IP International Journal of Orthopaedic Rheumatology 7, no. 1 (2021): 17–23. http://dx.doi.org/10.18231/j.ijor.2021.005.

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Osteoarthritis (OA) of the knee is a degenerative, non-inflammatory joint condition marked by articular cartilage disintegration and the growth of new bone (osteophytes) at the joint surfaces and borders. It impairs one's ability to function and makes one disabled. It is the most common rheumatic disease. Because the Knee is a weight-bearing joint and a crutch joint, it is the most usually afflicted joint by Osteoarthritis.A Correlational study was conducted to find out the correlation between Knee Society Score (KSS) and Oxford Knee Score (OKS) on 142 Osteoarthritis Knees. Purposive sampling was used to collect data from the Orthopaedics OPD at AIIMS Jodhpur from October to December 2018.On evaluation, the mean age of the patients was 60.19±1.01. Bilateral Knee Osteoarthritis affected about 42% of the patients. Approximately half of the patients were obese. Only 34% of patients had compliance in physiotherapy. Analgesics and massage treatment are used by about 76% of the patients to relieve knee pain. In the Knee Society Score, the majority of the patients (82.4%) had a bad knee condition, with a mean score of 49.07±1.06. In OKS, about half of the patients (46.5%) had Moderate to Severe Knee Osteoarthritis, with a mean score of 22.69±7.09. The correlation coefficient between the Knee Society Score and the Oxford Knee Score is 0.660. As a consequence of the analysis, both scales have almost the same outcome, indicating that they are moderately associated. The Knee Society Score is highly associated with occupation and physiotherapy, whereas the Oxford Knee Score is significantly related to the patients' age alone. According to the study, there is a moderate correlation between the Knee Society Score (KSS) and the Oxford Knee Score (OKS). These scores should be included during the diagnosis of Knee Osteoarthritis for improved patient care.

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Bonanzinga, Tommaso, Pietro Conte, Giuseppe Anzillotti, et al. "Native intra-articular knee microbiome is a matter of facts: a systematic review of clinical evidence." EFORT Open Reviews 9, no. 10 (2024): 969–79. http://dx.doi.org/10.1530/eor-23-0191.

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Purpose Growing interest surrounds the role of human gut microbiome in the development of degenerative pathologies such as osteoarthritis (OA), but microbes have recently been detected also in other sites previously considered to be sterile. Evidence emerged suggesting that even native and osteoarthritic knee joints may host several microbial species possibly involved in the osteoarthritic degeneration. This is the first systematic review critically collecting all the available evidence on the existence and composition of knee intra-articular microbiome. Methods A systematic research on the PubMed, Cochrane and Google Scholar databases was performed. Human clinical studies investigating the presence of intra-articular microbiome in native osteoarthritic knee joints with next-generation sequencing techniques were collected. Results A total of eight studies were included reporting data on 255 knees. All the included studies reported evidence supporting the existence of an intra-articular microbiome in native knee joints, with detection rates varying from 5.8% to 100%. Bacteria from the Proteobacteria phylum were found to be among the most identified followed by the Actinobacteria, Firmicutes, Fusobacteria, and Bacteroideta phyla. Proteobacteria phylum were also found to be more common in osteoarthritic knees when compared to healthy joints. Furthermore, several pathways correlating those microbes to knee OA progression have been suggested and summarized in this review. Conclusions Evidence collected in this systematic review suggests that the native knee joint, previously presumed to be a sterile environment, hosts a peculiar intra-articular microbiome with a unique composition. Furthermore, its alteration may have a link with the progression of knee osteoarthritis.

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Butarbutar, John, Mirna Phandu, Kevin Lee, Earlene Tasya, and Wendell Sebastian Sulaeman. "Ultrasound-guided Genicular Nerve Ablation with Alcohol Solution for Knee Osteoarthritis: A Case Series." Medicinus 11, no. 2 (2023): 69. http://dx.doi.org/10.19166/med.v11i2.7531.

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<div class="WordSection1"><p>Genicular nerve ablation using radiofrequency (RF) is a common minimally invasive procedure for painful osteoarthritic knees. However, the high cost and unavailability of equipment in many healthcare centers made this inconvenient for some patients. Some case reports tried the cheaper and newer method, using an alcohol solution to ablate the genicular nerves, showing considerable improvement in the patient's pain, functional knee score, and quality of life. We have attempted the ultrasound-guided genicular nerve ablation using alcohol solution in 6 patients with knee osteoarthritis to complement the body of evidence. We found that the genicular nerve ablation using alcohol solution is an excellent method for relieving symptoms of knee osteoarthritis if knee pain is the main symptom.</p></div>

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Yadav, Gopal, Divesh Singh, and Abhinav Yadav. "Knee Varus as "Pre - Osteoarthritic Lesion" in Initiation and Progression of Knee Osteoarthritis in Perimenopausal Women." International Journal of Science and Research (IJSR) 13, no. 8 (2024): 712–16. http://dx.doi.org/10.21275/sr24809153454.

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Shapiro, Shane A., Jennifer R. Arthurs, Michael G. Heckman, et al. "Quantitative T2 MRI Mapping and 12-Month Follow-up in a Randomized, Blinded, Placebo Controlled Trial of Bone Marrow Aspiration and Concentration for Osteoarthritis of the Knees." CARTILAGE 10, no. 4 (2018): 432–43. http://dx.doi.org/10.1177/1947603518796142.

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ObjectiveBone marrow aspiration and concentration (BMAC) is becoming a more common regenerative therapy for musculoskeletal pathology. In our current pilot study, we studied patients with mild-to-moderate bilateral knee osteoarthritis, compared pain at 12-month follow-up between BMAC-injected and saline-injected knees, and examined cartilage appearance measured by magnetic resonance imaging (MRI) T2 quantitative mapping.DesignTwenty-five patients with mild-to-moderate bilateral osteoarthritic knee pain were randomized to receive BMAC into one knee and saline placebo into the other. Bone marrow was aspirated from the iliac crests, concentrated in an automated centrifuge, combined with platelet-poor plasma for knee injection, and compared with saline injection into the contralateral knee. Primary outcome measures were T2 MRI cartilage mapping at 6-month and Visual Analog Scale and Osteoarthritis Research Society International Intermittent and Constant Osteoarthritis Pain scores and radiographs at 12-month follow-up.ResultsConstant, intermittent, and overall knee pain remained significantly decreased from baseline at 12-month follow-up (all P ⩽ 0.01), with no apparent difference between BMAC- and saline-treated knees (all P ⩾ 0.54). A similar significant increase from baseline to 12-month follow-up regarding quality of life was observed for both BMAC- and saline-treated knees (all P ⩽ 0.04). T2 quantitative MRI mapping showed no significant changes as a result of treatment.ConclusionsBMAC is safe to perform and relieves pain from knee arthritis but showed no superiority to saline injection at 12-month follow-up. MRI cartilage sequences failed to show regenerative benefit with single BMAC injection. The mechanisms of action that led to pain relief remain unclear and warrant further studies.

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Abbas, Nauman, Sabir Khattak, Muhammad Umer Faheem, Naeem Ahmed Shah, Amer Aziz, and Latif Khan. "SAFE ZONE OF JOINT LINE ELEVATION FOR THE TREATMENT OF KNEE FLEXION CONTRACTURE PREVENTING MID-FLEXION INSTABILITY IN TOTAL KNEE REPLACEMENT." Journal of Ayub Medical College Abbottabad 36, no. 2 (2024): 234–39. https://doi.org/10.55519/jamc-02-13141.

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Background: In osteoarthritic knee, flexion deformity is caused by synovial inflammation, posterior femoral and tibial osteophytes tenting onto the capsule, ligamentous contracture and hamstring shortening. This study aimed to evaluate the safe zone of joint line elevation for the treatment of flexion knee contracture preventing mid-flexion instability in total knee replacement. Methods 51 knees with varus osteoarthritis undergoing TKA were evaluated. 39 knees with flexion contracture < 15°and 12 knees with flexion contracture >15°. 2-mm joint line elevation was performed in just 4 knees with >15° flexion contracture. The extension and flexion gaps were measured with traditional spacer block. Stability in coronal plane (varus & valgus stress) was assessed at 0,30,60 & 90 degrees. Sampling Technique was non probability consecutive. SPSS 23 was used for statistical analysis. Results: The study comprises 51 patients undergoing total knee replacement (TKA) for osteoarthritis, with a notable gender distribution (84.3% women, 15.7% men) and a mean age of 60.24±8.54 years. Of these, 41.2% had both knees affected, and joint elevation was performed in 23.5% with flexion contracture >15°. No instability was found in cases with joint line elevation. Flexion contracture analysis revealed asymmetry across sides, yet no statistically significant differences. Detailed comparisons show variability in flexion contracture and range of motion, emphasizing the complexity of side-specific outcomes. The study underscores the importance of tailored evaluation and intervention for flexion contracture >15° to optimize postoperative results. Conclusions This study has shown that in patients with varus osteoarthritis of the knee and flexion contracture > 15°, a 2-mm joint line elevation is safe to treat knee flexion contracture and is not associated with mid-flexion laxity. Level of evidence IV Cross sectional study.

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Lopresti, Adrian L., Stephen J. Smith, Shavon Jackson-Michel, and Timothy Fairchild. "An Investigation into the Effects of a Curcumin Extract (Curcugen®) on Osteoarthritis Pain of the Knee: A Randomised, Double-Blind, Placebo-Controlled Study." Nutrients 14, no. 1 (2021): 41. http://dx.doi.org/10.3390/nu14010041.

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Curcumin, a phytochemical from the spice turmeric, has anti-inflammatory properties and has been shown to have pain-relieving effects. In this 8-week, randomised, double-blind, placebo-controlled study, 101 adults with knee osteoarthritis received either 500 mg twice daily of a standardised curcumin extract (Curcugen®) or placebo. Outcome measures included the Knee Injury and Osteoarthritis Outcome Score (KOOS), knee pain ratings, Japanese Orthopaedic Association Score for Osteoarthritic Knees (JOA), PROMIS–29, and performance-based testing comprising the 40-m fast-paced walk test, 6-min walk test, timed up-and-go test, and 30-s chair stand test. Compared to the placebo, curcumin significantly reduced the KOOS knee pain score (p = 0.009) and numeric knee pain ratings (p = 0.001). Curcumin was also associated with greater improvements (p ≤ 0.05) than the placebo on the timed up-and-go test, 6-min walk test, and the JOA total score; but not the 30-s chair stand test or 40-m fast-paced walk test. Pain-relieving medication was reduced in 37% of participants on curcumin compared to 13% on placebo. The findings support the potential efficacy of curcumin for the treatment of osteoarthritis of the knee but studies of longer duration, varying treatment doses, differing curcumin extracts, and the use of other objective outcome measures will be helpful to expand on these findings.

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Dissertations / Theses on the topic "Knee osteoarthritis"

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Schmitt, Laura Clare. "Knee stabilization and medial knee osteoarthritis." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 0.80 Mb., 201 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3220738.

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Soni, Anushka. "Pain characterisation in knee osteoarthritis." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:4026d694-8e7b-47f5-9f05-9f5a7b2165a0.

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Osteoarthritis (OA) is the most common form of arthritis in the world, and it has been estimated that about one tenth of the world's population, aged over 60, have symptoms that can be attributed to OA. Despite the size of the global impact of OA, there is a significant unmet need for effective treatments. Knee replacement surgery is commonly used in patients with moderate to severe knee OA, in order to reduce pain. However, 10-34% of patients report an unfavourable long-term outcome with persistent pain after surgery. The neural mechanisms for the generation of pain in knee OA are not fully understood. Previous work has shown that around 20% of patients have features of neuropathic pain, and that the underlying mechanism for this may be through central sensitisation. This mechanism-based understanding of pain is important in order to aid targeted intervention, and it may be that this patient group is more likely to have an adverse outcome following surgery. This thesis uses a combination of methods to investigate the neural mechanisms underlying pain experienced by patients with knee OA, across the full spectrum of disease severity. Quantitative sensory testing (QST) was initially used in a community-based cohort to show that pain sensitisation can be detected in early disease, and also contributes to the observed discordance between radiographic structural and symptomatic disease. The clinical relevance of neuropathic pain was then investigated in patients with knee OA, who were awaiting knee replacement surgery. Prior to surgery patients with neuropathic pain had increased sensitivity to experimental pain, as well as higher symptom severity and psychological distress. Functional magnetic resonance imaging (fMRI) was then used to confirm that these features were also associated with central sensitisation in the form of increased descending facilitation as well as reduced descending inhibition prior to surgery. The presence of neuropathic pain prior to surgery was associated with statistically and clinically significantly worse outcome following surgery, compared to those with purely nociceptive pain in the absence of any significant structural differences between the two groups. Taken together, this mechanism-based understanding of the pain provides an opportunity for targeted therapy prior to surgery, which may enhance outcome following surgery.

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Metcalfe, Andrew John. "Knee osteoarthritis is a bilateral disease." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/67638/.

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Knee osteoarthritis (OA) is a common cause of pain and disability. Patients often complain that they overload the other limb when they walk, resulting in disease in the unaffected knee. However, it is unknown whether this happens or the mechanism by which it occurs. Data was analysed from an established longitudinal cohort study to examine the development of bilateral knee OA. One hundred and forty-three subjects were examined over a 12 year period with bilateral radiographs. Bilateral knee osteoarthritis was found to be very common over time, and the majority of individuals with unilateral knee OA eventually developed bilateral disease. A gait analysis study was performed on 20 subjects with unilateral knee OA awaiting arthroplasty surgery and 20 healthy age equivalent controls. Abnormal moments and muscle co-contractions were observed in the other knee and hips when they walked due a characteristic slow, cautious, stiff-legged gait pattern. Fifteen subjects re-attended 12 months following their surgery. Whilst moments returned to normal in most of the replaced knees, they remained elevated at the contra-lateral side and co-contraction failed to recover in either knee. A novel study design is presented to examine the effect of gait-derived loading waveforms on fresh human osteochondral plugs. By applying mechano-biology techniques and Finite Element Modelling to fresh human tissue, new observations vi can be made about the relationship between in-vivo loading and cartilage mechano-biology. A characteristic gait pattern was observed in knee OA which is not simply antalgic but tends towards symmetry, with an increase in joint loading bilaterally. The observed gait behaviour does not resolve, despite arthroplasty of the affected joint. This would be expected to contribute to the development of disease in an inherently vulnerable joint. Additional training may have a role to play in restoring normal biomechanics and protecting the other knee from disease.

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Smith, Stephanie L. "Neuromuscular control in knee osteoarthritis (NEKO)." Thesis, Glasgow Caledonian University, 2016. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726764.

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Woods, Robert Jeffrey. "Biomechanics and osteoarthritis of the knee." Connect to resource, 1995. http://rave.ohiolink.edu/etdc/view.cgi?acc%5Fnum=osu1262616270.

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Krishnasamy, Priathashini. "The Role of Skeletal Muscle in the Incidence and Progression of Knee Osteoarthritis." Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20699.

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Skeletal muscle quality may play a role in skeletal muscle health affecting its response to muscle strengthening exercises and susceptibility to osteoarthritis (OA). Chapter One of this thesis provides an introduction to the role of skeletal muscle in the incidence, progression and exercise management of knee OA. Chapter Two examines skeletal muscle quality (muscle attenuation and lean muscle volume), knee extensor strength and percentage whole-body fat as mediators in the symptomatic and functional improvements achieved in a diet and exercise (D+E) compared to D (diet) or E (exercise) interventions. Null mediation results were found for skeletal muscle quality and knee extensor strength. However, a reduction in the percentage of whole- body fat significantly partially mediated pain, function, 6-minute walk test and gait speed improvements achieved in the D+E compared to E groups. Chapter Three presents the relationship between a change in lower extremity lean mass (LM) and fat mass (FM) with radiographic knee OA (RKOA) incidence in women longitudinally and concurrently. A 2-year change in LM or FM measures did not predict subsequent RKOA incidence. A 5-year increase of LM percentage was associated with a 10% reduced odds of RKOA incidence (OR 0.90, 95% CI 0.82-0.98, P=0.016]. A 0.25 unit increase in LM:FM ratio over 5 years was associated with a 31% reduced odds of RKOA incidence [OR 0.69, 95% CI 0.49-0.97, P=0.032]. Thigh muscle quality and knee extensor strength did not mediate symptomatic and functional improvements, however, a reduction in percentage whole-body fat partially mediated symptomatic and functional improvements achieved in a D+E compared to E groups. Lower extremity LM and FM changes were significantly associated with RKOA incidence concurrently, but did not precede RKOA incidence longitudinally. Further understanding of skeletal muscle properties would enable a higher treatment effect size to be achieved from rehabilitation programmes in knee OA.

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McAlindon, Timothy Edward. "Knee joint failure." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386627.

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Petterson, Stephanie Christine. "Knee osteoarthritis and total knee arthroplasty quadriceps weakness, rehabilitation, and recovery /." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 1.02 Mb., 222 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3205435.

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Crenshaw, Jeremy. "Knee-joint loading variability during gait in subjects with knee osteoarthritis." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 42 p, 2007. http://proquest.umi.com/pqdweb?did=1338917851&sid=5&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Parekh, Sanjay M. "The risk of knee pain and knee osteoarthritis in professional footballers." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43010/.

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Introduction: Knee osteoarthritis (KOA) is a common complex disorder. Although previously believed to be degenerative, KOA is in fact a regenerative condition, compensating against insults sustained at the joint. However, a failure of this compensatory repair process, especially in the presence of constitutional and local joint factors, increases the risk of KOA and inevitably leads to joint-failure (Dieppe and Lohmander, 2005, Arden and Nevitt, 2006, Sandell, 2012). Diagnosis of KOA may be made via clinical presentation, imaging, or using clinical algorithms, which may be a combination both in addition to biochemical diagnostic tests (Brandt et al., 2003). Knee pain (KP) is the most common symptom, and in the general population its prevalence is 25% (Peat et al., 2001a). Patients may also experience early morning stiffness of the joint and reduced function. Physician-observed signs include crepitus, restricted movement, and bony and soft tissue swellings (Abhishek and Doherty, 2013). Although considered the gold standard to diagnose KOA, plain film radiography is not without its limitations (Wick et al., 2012). Clinicians, however, favour radiography because it can easily discern two key features of the condition: joint space narrowing (JSN), a surrogate of cartilage loss, and the formation of osteophytes on the joint margin (Roemer et al., 2014). Assessment of radiographs is most commonly undertaken using Kellgren-Lawrence (KL) grade verbal descriptors (Altman et al., 1986a). The prevalence of radiographic KOA (RKOA) may be higher than KP, but there is a discordance between people reporting symptoms and those with structural change (RKOA) (Peat et al., 2001a, Bedson and Croft, 2008). A plethora of constitutional risk factors and joint-specific biomechanical factors increase the risk of KOA, including joint injury and occupation (Suri et al., 2012, Silverwood et al., 2015). One such occupation, which has a greater risk of injury are professional footballers (Drawer and Fuller, 2002) and knee injuries account for 17% of all footballing injuries (Ekstrand et al., 2011). Football is one of the most common team sports worldwide, with over 265 million people worldwide play the game (FIFA, 2007a), and of these, 110,000 are male professional footballers (FIFA, 2007b). Although perceived that that footballers are at great risk of long-term consequences such as KOA, due to their high risk of injury, the current evidence supporting this is limited (Kuijt et al., 2012, Tran et al., 2016). The previous studies observing KOA in footballers are difficult to generalise to the wider football population. This is for a number of reasons, including recruitment of inadequate sample, absence of inappropriate control groups, and differing case definitions, all resulting in a large variation in prevalence of KOA. Thus, there exists a need for a comprehensive study to determine the true prevalence and risk of KOA in retired professional footballers compared to the general population. Aims: (1) To determine the prevalence and risk of KOA (measured as KP, RKOA and requirement for total knee replacement (TKR)) in retired professional footballers compared to the general population; (2) To determine the specific factors (constitutional, biomechanical and football-specific) that are associated with an increased risk of each of these outcomes (KP, RKOA and TKR) within footballers. Methods: The Nottingham University Hospitals NHS Trust and the Nottingham Research Ethics Committee (Refs 14/EM/0045; 14/EM/0015) approved this study, which was registered on the clinicaltrials.gov portal (NCT02098044; NCT02098070). This study design involved carrying out two cross-sectional studies. The Football Study involved distributing 4775 postal questionnaire surveys to retired professional footballers via multiple sources, including football clubs, their former players’ associations and the Professional Footballers Association (PFA). The Knee Pain and Related Health in the Community Study (KPIC) involved distributing 40,500 postal questionnaires, via 12 general practice surgeries, to both men and women in the East Midlands general population. However, only men formed the control group for this study. The inclusion criteria for both the footballers and control participants was the same: men aged 40 and older. The questionnaires, developed based on previously literature, were similar to capture detailed information about KP, undergoing a TKR and putative risk factors for KOA, including knee injuries, surgery and alignment. The questionnaires also gathered information regarding demographics, medical and occupational history, general health and current medication. Following this, footballers and controls who consented had radiographic assessments of both their knees, including weight-bearing semi-flexed posterior-anterior (PA) view using the Rosen template (Rosenberg et al., 1988) and a seated 30° flexion skyline view. A single observer (GSF) scored all the radiographs as a single mixed batch using HIPAX Dicom software. In addition to the KL grades, the Nottingham Line Drawing Atlas (NLDA) was used (Nagaosa et al., 2000) (Wilkinson et al., 2005), which scored composite joint space narrowing (JSN), composite osteophyte, and a combined global score for each knee. Primary outcomes observed were current KP, RKOA (measured using the NLDA) and TKR. Secondary outcomes observed were ever having KP (chronic), physician-diagnosed KOA, RKOA (measured using KL grades) and radiographic CC. Power calculations determined the sample size for the questionnaire survey and the radiographic survey. Categorical variables presented as frequency and percent and compared using a chi-squared test. Continuous variables presented as mean and standard deviation and compared using a t-test. The risk of KOA (measured for each outcome independently) in footballers compared to the controls was determined using a generalised linear model (GLM) with a Poisson distribution, and adjusted for known risk factors (including age, body mass index (BMI) and previous knee injury). The specific risk factors within footballers associated with outcomes of KOA (namely KP, RKOA and TKR) were determined using multivariate logistic regression. Results: 1207 footballers (response rate of 25.3%) and 4085 control men responded to the Football and KPIC studies respectively, which was far lower than studies previously conducted in both populations. Following this, 470 footballers and 500 men consented to undergoing radiographic assessment of their knees. For participants who returned the questionnaire (footballers and controls), characteristics were compared between those who underwent a knee radiograph and those who did not. Age and sustaining a knee injury were the main factors significantly difference in both. Footballers were significantly older (3.9 years) than the controls, but were gender-matched (males-only) and had a similar BMI. Footballers had a significantly greater number of injuries (64.5% v. 23.3%) compared to the controls. They also had significantly more body pain (74.7% v. 69.8%) and therefore took more pain-relief medication (61.9% v. 28.5%). However, footballers suffered from far fewer comorbidities compared to the controls (29.4% v. 45.7%). Footballers had a far greater prevalence of both primary and secondary outcomes. The prevalence of KP was almost twice as great in footballers (52.2%) compared to the controls (26.9%) and this increased prevalence was regardless of age. The peak prevalence of KP also occurred at least ten years earlier in footballers compared to the controls. Although the prevalence of physician-diagnosed KOA was much lower than the prevalence of KP in footballers (28.3%), it was more than double that of the controls (12.2%). Additionally, footballers (11.1%) had almost three times greater prevalence of TKR compared to the controls. Risk factors significantly associated with footballers who had undergone a TKR, included age [OR 1.09, 95% CI 1.07-1.11], being obese [OR 1.77, 95% CI 1.00-3.12] and having gout [OR 3.11, 95% CI 1.96-4.70]. Sustaining a significant knee injury [OR 3.11, 95% CI 1.94-4.99] and receiving an intra-articular knee injection [OR 2.56, 95% CI 1.76-3.73] were also significant risk factors for footballers who underwent a TKR. However, those footballers with a longer duration of playing the game [OR 0.95, 95% CI 0.92-0.98] had a reduced risk of TKR.<br>Conclusion: These findings show footballers have a greater risk of KOA compared to the general population, reporting up to three times higher prevalence of various outcomes (KP, RKOA, physician-diagnosed KOA and TKR). The age-prevalence of all outcomes of KOA, are greater in footballers compared to the controls. The high prevalence of injuries significantly account the risk of KOA in footballers compared to the controls (even following adjustment of other risk factors). Within footballers, knee injuries, together with subsequent investigations (specifically exploratory and interventional arthroscopy) and management (specifically intra-articular knee injections), were strongly associated with risk of KOA (KP, RKOA and TKR independently). Football’s governing bodies need to set out and implement strategies to reduce or even prevent the risk of serious injury (thus reducing the risk of subsequent investigation). This will reduce the risk of long-term consequences, such as KOA. However, whether the Industrial Injuries Advisory Council considers the risk of KOA in footballers an industrial compensable disease remains a question.

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Books on the topic "Knee osteoarthritis"

1

Bonnin, Michel, and Pierre Chambat. Osteoarthritis of the knee. Springer Paris, 2008. http://dx.doi.org/10.1007/978-2-287-74175-3.

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Rodríguez-Merchán, E. Carlos, and Primitivo Gómez-Cardero, eds. Comprehensive Treatment of Knee Osteoarthritis. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44492-1.

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Bramble, Leigh-Ann Alexandra. Physical Activity in Adults With Knee Osteoarthritis. [publisher not identified], 2019.

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Verfasser, Schäfer Robert 1965, and Franz Wolfgang 1958-, eds. Osteoarthritis of the knee: Prevention, treatment, cure. Me&Friends, 2008.

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Koshino, Tomihisa. High tibial osteotomy and knee arthroplasty for osteoarthritis and rheumatoid arthritis. Department of Orthopaedic Surgery, Yokohama City University School of Medicine, 2006.

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Parker, David, ed. Management of Knee Osteoarthritis in the Younger, Active Patient. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-48530-9.

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Parvizi, Javad. The knee: Reconstruction, replacement, and revision. Data Trace Pub. Co., 2012.

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M, Bert Jack, ed. The treatment of unicompartmental arthritis of the knee. Saunders, 2005.

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Rhematology, British Society of. Guidelines: Diagnosis and management of osteoarthritis of the hip and knee. Royal College of Physicians of London, 1993.

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Boegard, Torsten. Radiography and bone scintigraphy in osteoarthritis of the knee: -comparison with MR imaging. Munksgaard, 1998.

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Book chapters on the topic "Knee osteoarthritis"

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Hung, Cynthia, and Mohamed S. Ahmed. "Knee Osteoarthritis." In Musculoskeletal Sports and Spine Disorders. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50512-1_56.

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Katz, Jeffrey N., and Thomas S. Thornhill. "Knee Osteoarthritis." In Principles of Orthopedic Practice for Primary Care Providers. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-68661-5_16.

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Katz, Jeffrey N., Kaetlyn R. Arant, and Thomas S. Thornhill. "Knee Osteoarthritis." In Principles of Orthopedic Practice for Primary Care Providers. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74625-4_24.

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Dzaja, Ivan, and Khalid Syed. "Hip and Knee Osteoarthritis." In Osteoarthritis. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19560-5_2.

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Kirmair, J. "Knee School: Practical Management in Rehabilitation." In Osteoarthritis. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-87752-0_17.

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Edelson, Richard H. "Knee Washout for Osteoarthritis." In Advances in Osteoarthritis. Springer Japan, 1999. http://dx.doi.org/10.1007/978-4-431-68497-8_16.

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Ruiz-Pérez, Juan S., Primitivo Gómez-Cardero, and E. Carlos Rodríguez-Merchán. "Tricompartmental Knee Osteoarthritis: Total Knee Arthroplasty." In Comprehensive Treatment of Knee Osteoarthritis. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44492-1_10.

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Rodríguez-Merchán, E. Carlos, Primitivo Gómez-Cardero, and Carlos A. Encinas-Ullán. "Unicompartmental Knee Osteoarthritis: Unicompartmental Knee Arthroplasty." In Comprehensive Treatment of Knee Osteoarthritis. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44492-1_9.

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Grifka, J., T. Kalteis, and W. Plitz. "Cartilage Destruction of the Knee Due to Partial Meniscal Resection." In Osteoarthritis. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-87752-0_13.

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Bert, Timothy M., and Jack M. Bert. "Arthroscopic Approach to Knee Osteoarthritis." In The Knee. CRC Press, 2024. http://dx.doi.org/10.1201/9781003524755-18.

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Conference papers on the topic "Knee osteoarthritis"

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Rawat, Ashutosh, Anurag Dhyani, Deepanshu Panwa, Gautam Bisht, Satvik Vats, and Vikrant Sharma. "Knee Osteoarthritis Prediction using Transfer Learning." In 2024 IEEE 3rd World Conference on Applied Intelligence and Computing (AIC). IEEE, 2024. http://dx.doi.org/10.1109/aic61668.2024.10731036.

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Fall, Mame Diarra. "Quantifying Uncertainty in Knee Osteoarthritis Diagnosis." In 2024 IEEE International Symposium on Biomedical Imaging (ISBI). IEEE, 2024. http://dx.doi.org/10.1109/isbi56570.2024.10635586.

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Shanthini, E., Sindhu M, Sharmithaa Sri B. B, and Swathi Shree S. L. "Knee Osteoarthritis Severity Classification Using STM32 Microcontroller." In 2024 IEEE International Conference on Information Technology, Electronics and Intelligent Communication Systems (ICITEICS). IEEE, 2024. http://dx.doi.org/10.1109/iciteics61368.2024.10625261.

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Divyanshi and Saumya Bansal. "Detecting Severity Level of Knee Osteoarthritis using CNN." In 2024 15th International Conference on Computing Communication and Networking Technologies (ICCCNT). IEEE, 2024. http://dx.doi.org/10.1109/icccnt61001.2024.10724941.

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Guhan, T., RM Abiraj, M. Muneshwaran, V. Sowndharya Lakshmi, and M. Suriyanarayanan. "Classification of Knee Osteoarthritis Using R-CNN Algorithm." In 2025 International Conference on Multi-Agent Systems for Collaborative Intelligence (ICMSCI). IEEE, 2025. https://doi.org/10.1109/icmsci62561.2025.10894085.

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Singh, Rahul, Neha Sharma, Deepak Upadhyay, Sarishma Dangi, and Akira Singh. "Proposed CNN Model for the Classification of Knee Osteoarthritis." In 2024 IEEE 3rd World Conference on Applied Intelligence and Computing (AIC). IEEE, 2024. http://dx.doi.org/10.1109/aic61668.2024.10730849.

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Al-Nabulsi, Jamal, Mohammad Al-Sayed Ahmad, Baraa Hasaneiah, and Fayhaa AlZoubi. "Diagnosis of Knee Osteoarthritis Using Bioimpedance & Deep Learning." In 2024 Second Jordanian International Biomedical Engineering Conference (JIBEC). IEEE, 2024. https://doi.org/10.1109/jibec63210.2024.10931925.

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MohamedEsmaeil, Lamia Nabil, Dalia Ali, and Ayman Khalifa. "Automatic Diagnosis of Knee Osteoarthritis Using Deep Learning Approaches." In 2024 International Conference on Computer and Applications (ICCA). IEEE, 2024. https://doi.org/10.1109/icca62237.2024.10927936.

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Ji, Dongsheng, Dandan Zou, and Xiangzeng Chen. "Deep Learning-Based Knee Osteoarthritis MRI Image Classification Method." In 2025 2nd International Conference on Smart Grid and Artificial Intelligence (SGAI). IEEE, 2025. https://doi.org/10.1109/sgai64825.2025.11009413.

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Singh, Shubham Kumar, Kuldeep Chouhan, and Arun Prakash Agrawal. "Osteoarthritis Prediction in Knee Joint Using Deep Learning Techniques." In 2024 27th International Symposium on Wireless Personal Multimedia Communications (WPMC). IEEE, 2024. https://doi.org/10.1109/wpmc63271.2024.10863523.

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Reports on the topic "Knee osteoarthritis"

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Xu, Zhiteng, and Renbin Li. A systematic review and meta-analysis of outcomes following unicompartmental knee arthroplasty versus total knee arthroplasty for unicondylar knee osteoarthritis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0003.

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Review question / Objective: To conduct a systematic review and meta-analysis of randomized controlled trials comparing outcomes following unicompartmental knee arthroplasty versus total knee arthroplasty for patients with unicondylar knee osteoarthritis. Condition being studied: Knee osteoarthritis is a common disease in elderly population and its treatment strategies consist of non-operative treatment and surgery. Arthroplasty is a main surgery for this condition, while the optimal selection between unicompartmental knee arthroplasty and total knee arthroplasty remains debatable. We aim to collect RCTs comparing these two techniques in treatment of knee osteoarthritis and make a meta-analysis in order to provide high level of evidence for future decision-making for this issue.

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Huang, Zeling, Xiao Mao, Junming Chen, et al. Sinomenine hydrochloride injection for knee osteoarthritis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.11.0057.

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Review question / Objective: At present, many clinical studies have been reported on the treatment of KOA by injecting sinomenine hydrochloride into the knee cavity. However, no systematic evaluation has been published on this issue, and it is not clear whether sinomenine hydrochloride injection is effective and safe in the treatment of KOA.Therefore, it is important to conduct systematic evaluation to obtain relatively convincing conclusions as to whether sinomenine hydrochloride injection can be a good choice as a complementary and alternative drug (CAM) for KOA. Condition being studied: The RCTs are eligible, whether or not the blind method is specifically described. There are no restrictions on languages. Moreover, systemic evaluation, review literature and the full article cannot be obtained will be excluded.

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Li, Jia, Yuan Liu, Jing Zhang, and Mingxing Yuan. Neuroimaging studies of acupuncture on knee osteoarthritis: a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0110.

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Review question / Objective: This study was conducted in order to investigate the study design and main outcomes of acupuncture neuroimaging studies on knee osteoarthritis (KOA),and reveal the potential mechanism of the pain-relieving effect of acupuncture on knee osteoarthritis. Condition being studied: Knee osteoarthritis is a very common disease that seriously affects people's quality of life. Acupuncture, as an effective treatment option, can achieve pain relief and treat the disease, but the mechanism of acupuncture analgesia is still unclear to us. Therefore, we set certain criteria to include eligible clinical trials to reveal its principles.

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Guryanova, E. A., Yu V. Polyakova, and M. A. Matveeva. SHOCK WAVE THERAPY FOR OSTEOARTHRITIS OF THE KNEE. Publishing house FSAEI of HE "KFU im. IN AND. Vernadsky, 2019. http://dx.doi.org/10.18411/2413-0478-2019-2-57-61.

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Shen, Cimin, Na Li, Chen Bin, et al. Thermotherapy for knee osteoarthritis: a systematic review protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.4.0038.

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Newberry, Sydne J., John FitzGerald, and Nelson F. SooHoo. Treatment of Osteoarthritis of the Knee: An Update Review. Agency for Healthcare Research and Quality (AHRQ), 2017. http://dx.doi.org/10.23970/ahrqepccer190.

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Guede-Rojas, Francisco, Alexis Benavides-Villanueva, Sergio Salgado-González, Cristhian Mendoza, Gonzalo Arias-Álvarez, and Claudio Carvajal-Parodi. Effect of strength training on knee proprioception in patients with knee osteoarthritis. A systematic review and meta-analysis protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.5.0102.

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Review question / Objective: To analyze the effect of strength training (ST) on knee proprioception in patients with knee osteoarthritis (KOA). Condition being studied: KOA is a chronic and degenerative joint disease characterized by articular cartilage loss, marginal bone hypertrophy, and inflammatory involvement of periarticular tissue of the knee. Symptoms of KOA are pain, stiffness, reduced range of motion, and muscle weakness, although proprioception may also be affected, contributing to the associated functional limitation.

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Wang, Kai, Wei Song, Li Chen, et al. Acupuncture for knee osteoarthritis: a systematic review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.11.0086.

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Wang, Lidong, Xun Xie, Yizhuo Yang, and LIping Jiang. Effect of Balneology on Patients with Knee Osteoarthritis: A Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.12.0140.

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Schäublin, Jonas. Supervised exercises versus home based exercises in people with knee osteoarthritis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.1.0072.

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