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Journal articles on the topic 'Knee osteoarthritis (OA)'

Author: Grafiati

Published: 19 February 2023

Last updated: 31 July 2025

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1

Brigham, Christopher R., Charles N. Brooks, and James B. Talmage. "Knee Osteoarthritis." Guides Newsletter 10, no. 2 (2005): 1–3. http://dx.doi.org/10.1001/amaguidesnewsletters.2005.marapr01.

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Abstract More than 20 million Americans have osteoarthritis (OA), which affects the knee more often than any other joint and is the most common cause of long-term disability in persons older than 65 years. Knee OA is common, particularly in older patients and especially the obese. Knee injury, depending on the severity and type, can increase the risk of developing and the rate of progression of OA. In assessing impairment for knee OA, the evaluator must obtain a thorough history and physical examination and identify all potential risk factors. To opine that an injury caused OA, the evaluator s

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Wilder, Frances Vaughn, Paul E. Leaverton, Matthew W. Rogers, and Nancy B. Lemrow. "VITAMIN SUPPLEMENTS AND RADIOGRAPHIC KNEE OSTEOARTHRITIS: THE CLEARWATER OSTEOARTHRITIS STUDY." Journal of Musculoskeletal Research 12, no. 02 (2009): 85–93. http://dx.doi.org/10.1142/s0218957709002274.

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Objective: To evaluate the association between vitamin supplements and the incidence and progression of radiographic knee osteoarthritis (OA). Study Design: Prospective cohort. Methods: Men and women aged 40 years and older (N = 2239) participating in the community-based Clearwater Osteoarthritis Study (1988–current) with biennial, sequential radiographs. The Lawrence & Kellgren ordinal scale was used to determine evidence of the study outcome, radiographic knee OA, and progression of radiographic knee OA. The study exposure was baseline history of self-reported vitamin supplement usage. R

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Linda Pertiwi, Ni Made, and Ni Luh Jaya Kirana. "Conventional Radiography of Grade III Knee Osteoarthritis: A Case Report." International Journal of Research and Review 10, no. 10 (2023): 536–40. http://dx.doi.org/10.52403/ijrr.20231068.

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Introduction: Osteoarthritis (OA) is the most common form of inflammatory joint disease. It occurs most frequently in the knees, hips, the spine (vertebrae), and ankles. Radiological prevalence of knee OA in Indonesia reaches 15.5% in men and 12.7% in women aged between 40-60 years. X-ray imaging is routinely used in clinical practice to confirm knee OA diagnosis and in clinical research to monitor the progression of knee OA. Case report: A 62-year-old female patient presented with knee pain in both knees that had been ongoing for the past 6 months. The pain was described as throbbing and stab

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Auday Hussain Hassan Al-Janaby. "Knee osteoarthritis severity concerning neutrophil-lymphocyte ratio." Magna Scientia Advanced Research and Reviews 2, no. 2 (2021): 080–84. http://dx.doi.org/10.30574/msarr.2021.2.2.0054.

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Osteoarthritis (OA) is a disease with a significant inflammatory component. Neutrophil-lymphocyte ratio (NLR) level is a marker to determine inflammation. The study aimed to evaluate the association between the severity of knee OA and NLR. A case-control study was conducted in Al-Zahrawi from June 2017 to June 2018. A total of 100 knees OA were recruited and 50 healthy subjects as a control group. NLR was significantly higher in knee OA than controls, the mean value was (2.19±0.72) and (1.97±0.88), respectively. Older age, chronic pain, prolong the onset of diagnosis and high NLR were signific

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De Roos, Anneclaire J., Lenore Arab, Jordan B. Renner, et al. "Serum carotenoids and radiographic knee osteoarthritis: the Johnston County Osteoarthritis Project." Public Health Nutrition 4, no. 5 (2001): 935–42. http://dx.doi.org/10.1079/phn2001132.

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AbstractObjective:Antioxidant intake has been associated with less progression of radiographic knee osteoarthritis (OA), but studies of carotenoid biomarkers and OA have not been done. We examined associations between serum concentrations of nine naturally occurring carotenoids and radiographic knee OA.Design:The study design was matched case–control. Sera were analysed by high-performance liquid chromatography for nine carotenoids: lutein, zeaxanthin, α- and β-cryptoxanthin, trans- and cis-lycopene, α-carotene, and trans- and cis-β-carotene. Conditional logistic regression was used to estimat

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Liebl, Hans, Gabby Joseph, Michael C. Nevitt, et al. "Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative." Annals of the Rheumatic Diseases 74, no. 7 (2014): 1353–59. http://dx.doi.org/10.1136/annrheumdis-2013-204157.

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ObjectiveTo evaluate whether T2 relaxation time measurements obtained at 3 T MRI predict the onset of radiographic knee osteoarthritis (OA).Materials and methodsWe performed a nested case–control study of incident radiographic knee OA in the Osteoarthritis Initiative cohort. Cases were 50 knees with baseline Kellgren–Lawrence (KL) grade of 0 that developed KL grade of 2 or more over a 4-year period. Controls were 80 knees with KL grade of 0 after 4 years of follow-up. Baseline T2 relaxation time measurements and laminar analysis of T2 in deep and superficial layers were performed in all knee c

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Kanthavel, R., and R. Dhaya. "PROGRESS AND PRECLUSION OF KNEE OSTEOARTHRITIS: A STUDY." September 2021 3, no. 3 (2021): 150–62. http://dx.doi.org/10.36548/jitdw.2021.3.001.

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There is a need for better medical and preclinical instruments to diagnose knee OA in its initial phases owing to the increase occurrence of knee osteoarthritis (OA), a devastating knee joint degeneration. Osteoarthritis commonly affects patients who are obese and those above the age of 60. This mainly happens to age down and over-weighted people. The goal is to provide practical methods for assessing the seriousness of knee OA quickly and with human consistency. We also present Changes that affect your chances of getting sick of knee osteoarthritis, Treatment of knee osteoarthritis and the Pr

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Guida, Carmine, Ming Zhang, and Juan Shan. "Knee Osteoarthritis Classification Using 3D CNN and MRI." Applied Sciences 11, no. 11 (2021): 5196. http://dx.doi.org/10.3390/app11115196.

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Osteoarthritis (OA) is the most common form of arthritis and can often occur in the knee. While convolutional neural networks (CNNs) have been widely used to study medical images, the application of a 3-dimensional (3D) CNN in knee OA diagnosis is limited. This study utilizes a 3D CNN model to analyze sequences of knee magnetic resonance (MR) images to perform knee OA classification. An advantage of using 3D CNNs is the ability to analyze the whole sequence of 3D MR images as a single unit as opposed to a traditional 2D CNN, which examines one image at a time. Therefore, 3D features could be e

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JONES, RICHARD K., GRAHAM J. CHAPMAN, ANDREW H. FINDLOW, et al. "A New Approach to Prevention of Knee Osteoarthritis: Reducing Medial Load in the Contralateral Knee." Journal of Rheumatology 40, no. 3 (2013): 309–15. http://dx.doi.org/10.3899/jrheum.120589.

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Objective.Few if any prevention strategies are available for knee osteoarthritis (OA). In those with symptomatic medial OA, the contralateral knee may be at high risk of disease, and a reduction in medial loading in that knee might prevent disease or its progression there. Our aim was to determine how often persons with medial OA on 1 side had either concurrent or later medial OA on the contralateral side, and whether an intervention known to reduce medial loading in affected knees with medial OA might reduce medial loading in the contralateral knee. Lateral wedge insoles reduce loading across

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Lin, Jianhao, Rujun Li, Xiaozheng Kang, and Hu Li. "Risk Factors for Radiographic Tibiofemoral Knee Osteoarthritis: The Wuchuan Osteoarthritis Study." International Journal of Rheumatology 2010 (2010): 1–6. http://dx.doi.org/10.1155/2010/385826.

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Objective. To investigate the risk factors of radiographic tibiafemoral knee osteoarthritis (OA).Methods. A population-based cross-sectional survey was conducted in Wuchuan County. A questionnaire and bilateral weight-bearing posterior-anterior semi-flexed knee radiographs were completed and read for Kellgren and Lawrence (K/L) grade and joint space narrowing (JSN; 0–3 scale) in each compartment. An logistic regression analysis was performed for radiographic tibiafemoral, lateral compartment, and medial compartment knee OA, respectively. Adjusted odds ratios (OR) and 95% confidence intervals (

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Rocchetti, Maria Teresa, Davide Bizzoca, Lorenzo Moretti та ін. "A Gel-Based Proteomic Analysis Reveals Synovial α-Enolase and Fibrinogen β-Chain Dysregulation in Knee Osteoarthritis: A Controlled Trial". Journal of Personalized Medicine 13, № 6 (2023): 916. http://dx.doi.org/10.3390/jpm13060916.

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Background: The identification of synovial fluid (SF) biomarkers that could anticipate the diagnosis of osteoarthritis (OA) is gaining increasing importance in orthopaedic clinical practice. This controlled trial aims to assess the differences between the SF proteome of patients affected by severe OA undergoing Total Knee Replacement (TKR) compared to control subjects (i.e., subjects younger than 35, undergoing knee arthroscopy for acute meniscus injury). Methods: The synovial samples were collected from patients with Kellgren Lawrence grade 3 and 4 knee osteoarthritis undergoing THR (study gr

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Hasan, Mohd Shifa, Aditya Kumar Mishra, Mohd Bilal Kaleem, and Vikash Thaledi. "Cross-sectional study on the relationship between Body Mass Index and severity of knee osteoarthritis." Romanian Journal of Rheumatology 33, no. 1 (2024): 48–53. http://dx.doi.org/10.37897/rjr.2024.1.11.

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Background. Musculoskeletal diseases like osteoarthritis (OA) are widespread. OA affects the knees, makes the joints wear out and hurt, and makes it hard to move around. Body mass index (BMI) is a way to measure obesity, which is linked to a higher chance of getting OA and making it worse. The main aim of this cross-sectional study was to find out how body mass index (BMI) is related to how lousy knee osteoarthritis is. Methods. One hundred people at the Shri Guru Ram Rai Institute of Medical and Health Sciences in Dehradun met the study’s requirements and were enrolled. The Kellgren-Lawrence

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Driban, Jeffrey B., Easwaran Balasubramanian, Mamta Amin, Michael R. Sitler, Marvin C. Ziskin, and Mary F. Barbe. "The Potential of Multiple Synovial-Fluid Protein-Concentration Analyses in the Assessment of Knee Osteoarthritis." Journal of Sport Rehabilitation 19, no. 4 (2010): 411–21. http://dx.doi.org/10.1123/jsr.19.4.411.

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Context:Joint trauma is a risk factor for osteoarthritis (OA), which is becoming an increasingly important orthopedic concern for athletes and nonathletes alike. For advances in OA prevention, diagnosis, and treatment to occur, a greater understanding of the biochemical environment of the affected joint is needed.Objective:To demonstrate the potential of a biochemical technique to enhance our understanding of and diagnostic capabilities for osteoarthritis.Design:Cross-sectional.Setting:Outpatient orthopedic practice.Participants:8 subjects: 4 OA-knee participants (65 ± 6 y of age) and 4 normal

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Lyu, Shaw-Ruey. "Knee pain and osteoarthritis (Knee OA) treatment research." Open Access Government 39, no. 1 (2023): 48–49. http://dx.doi.org/10.56367/oag-039-10831.

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Knee pain and osteoarthritis (Knee OA) treatment research Professor Shaw-Ruey Lyu from the School of Medicine, Tzu-Chi University, discusses Knee Pain and Osteoarthritis (Knee OA) Treatment Research, in particular Knee Health Promotion Option (KHPO). Starting from 2002, I conducted a series of studies(1-3,5,6,8,9) to investigate medial abrasion phenomenon (MAP) as a cause of knee OA. I found a high correlation between medial plica-related MAP and knee OA. MAP would elicit lifelong interplay between a pathologic medial plica and the facing medial femoral condyle, and therefore plays a role in t

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Namirembe, Waldah, Joanita Namawejje, Wopotela D. Kisombo, and Ambrose Asiimwe. "KNOWLEDGE OF THE USE OF KNEE BRACES IN THE MANAGEMENT OF KNEE OSTEOARTHRITIS AMONG PATIENTS AGED 36 YEARS AND ABOVE IN MULAGO NATIONAL REFERRAL HOSPITAL. A CROSS-SECTIONAL STUDY." SJ Orthopaedic Research Africa 1, no. 8 (2024): 6. https://doi.org/10.51168/vsrew127.

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Background Patient education is an important first-line OA treatment necessary for enhancing the understanding and changing the attitude about OA and its optimal management. This study aims to assess the knowledge of knee braces use in managing knee osteoarthritis among patients aged 36 years and above in Mulago National Referral Hospital. Methodology The study was descriptive, and cross-sectional employing a quantitative data collection approach from 45 respondents. It included all male and female patients diagnosed with knee osteoarthritis in the orthopedic workshop. Results The majority 35(

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Bonanzinga, Tommaso, Pietro Conte, Giuseppe Anzillotti, et al. "Native intra-articular knee microbiome is a matter of facts: a systematic review of clinical evidence." EFORT Open Reviews 9, no. 10 (2024): 969–79. http://dx.doi.org/10.1530/eor-23-0191.

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Purpose Growing interest surrounds the role of human gut microbiome in the development of degenerative pathologies such as osteoarthritis (OA), but microbes have recently been detected also in other sites previously considered to be sterile. Evidence emerged suggesting that even native and osteoarthritic knee joints may host several microbial species possibly involved in the osteoarthritic degeneration. This is the first systematic review critically collecting all the available evidence on the existence and composition of knee intra-articular microbiome. Methods A systematic research on the Pu

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Bilovol, O. M., and I. I. Knyazkova. "Osteoarthritis." Medicine of Ukraine, no. 5-6(261-2) (September 14, 2022): 20–25. http://dx.doi.org/10.37987/1997-9894.2022.5-6(261-2).271643.

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Extreme interest in the problem of osteoarthritis (osteoarthrosis, OA) is due to the significant spread of this form of joint pathology. Research in recent years has made it possible to revise our ideas about the pathogenesis of this process with confirmation of the leading role of inflammation in the development of functional and structural damage in the specified pathology. The review article discusses the features of the pathogenesis of OA. It is noted that OA is a complex disease that affects not only cartilage tissue, but also intra-articular and peri-articular tissues. Clinical classific

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Rönn, Karolin, Nikolaus Reischl, Emanuel Gautier, and Matthias Jacobi. "Current Surgical Treatment of Knee Osteoarthritis." Arthritis 2011 (April 26, 2011): 1–9. http://dx.doi.org/10.1155/2011/454873.

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Osteoathritis (OA) of the knee is common, and the chances of suffering from OA increase with age. Its treatment should be initially nonoperative—and requires both pharmacological and nonpharmacological treatment modalities. If conservative therapy fails, surgery should be considered. Surgical treatments for knee OA include arthroscopy, cartilage repair, osteotomy, and knee arthroplasty. Determining which of these procedures is most appropriate depends on several factors, including the location, stage of OA, comorbidities on the one side and patients suffering on the other side. Arthroscopic la

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Naredo, Esperanza. "Ultrasonographic findings in knee osteoarthritis: a comparative study with clinical and radiographic assessment." Osteoarthritis Cartilage 13, no. 7 (2005): 568–74. https://doi.org/10.1016/j.joca.2005.02.008.

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Objective: To compare ultrasonographic (US) findings with clinical and radiographic assessment in knee osteoarthritis (OA). Methods: Fifty patients with primary knee OA were studied. Clinical assessment of both knees was performed by the same rheumatologist who recorded a visual analogue scale (VAS) for pain (VASP). All patients underwent a US examination of their knees by a second blinded rheumatologist. Weight-bearing anteroposterior and lateral knee radiographs were read by a third blinded rheumatologist who assessed the Kellgren and Lawrence (K-L) grade, the femorotibial (FT) spa

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Darma, I. Dewa Made Aditya, M. Widnyana, and Putu Ayu Sita Saraswati. "The relationship between obesity and knee osteoarthritis: a literature review." Kinesiology and Physiotherapy Comprehensive 4, no. 1 (2025): 8–14. https://doi.org/10.62004/kpc.v4i1.55.

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Background: Knee osteoarthritis (OA) is an chronic degenerative inflammatory disease of the knee. This study aimed to determine the relationship between obesity and knee OA. Objective: To explore and analyze more deeply the relationship between obesity and knee osteoarthritis. Methods: The research used a literature review design using secondary data in the form of a review of research journals related to obesity and the risk of osteoarthritis. The process of identifying relevant journals was conducted by searching the PubMed and Google Scholar databases using specific keywords such as "obesit

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Budhiparama, Nicolaas C., Imelda Lumban-Gaol, Herawati Sudoyo, Rahadyan Magetsari, and Tri Wibawa. "Interleukin-1 genetic polymorphisms in knee osteoarthritis: What do we know? A meta-analysis and systematic review." Journal of Orthopaedic Surgery 30, no. 1 (2022): 230949902210766. http://dx.doi.org/10.1177/23094990221076652.

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Purpose Interleukin-1 is the main proinflammatory cytokine in osteoarthritis (OA). Several single-nucleotide polymorphisms (SNPs) within the IL-1 gene cluster (IL-1β, IL-1R1, and IL-1RN) have been determined, but their associations with knee OA remain poorly understood. The present study aimed to identify the associations between IL-1 SNPs and knee osteoarthritis. Methods This meta-analysis and systematic review included all comparative studies published in the MEDLINE/PubMed, Embase, Google Scholar, and Cochrane Library databases. We performed a systematic search to identify relevant studies

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Cueva, Joseph Humberto, Darwin Castillo, Héctor Espinós-Morató, David Durán, Patricia Díaz, and Vasudevan Lakshminarayanan. "Detection and Classification of Knee Osteoarthritis." Diagnostics 12, no. 10 (2022): 2362. http://dx.doi.org/10.3390/diagnostics12102362.

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Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-automatic CADx model based on Deep Siamese convolutional neural networks and a fine-tuned ResNet-34 to simultaneously detect OA lesions in the two knees according to the KL scale. The training was done using a public dataset, whereas the validations were performed with a private dataset. Some problem

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Espinós-Morató, HECTOR. "Detection and classification of knee osteoarthritis." Diagnostics 12, no. 10 (2022): 2362. https://doi.org/10.3390/diagnostics12102362.

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Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-automatic CADx model based on Deep Siamese convolutional neural networks and a fine-tuned ResNet-34 to simultaneously detect OA lesions in the two knees according to the KL scale. The training was done using a public dataset, whereas the validations were performed with a private dataset. Some problem

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Kurtulus, Burhan, Numan Atilgan, Mehmet Yilmaz, and Recep Dokuyucu. "Two Members of Vitamin-K-Dependent Proteins, Gla-Rich Protein (GRP) and Matrix Gla Protein (MGP), as Possible New Players in the Molecular Mechanism of Osteoarthritis." Journal of Clinical Medicine 13, no. 17 (2024): 5159. http://dx.doi.org/10.3390/jcm13175159.

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Objectives: The pathophysiology of osteoarthritis is mainly unknown. Matrix Gla protein (MGP) and Gla-rich protein (GRP) are both vitamin-K-dependent mineralization inhibitors. In this study, we aimed to compare the levels of MGP and GRP in the synovial fluid of osteoarthritic (OA) and non-osteoarthritic (non-OA) knee joints. Materials and Methods: Two groups were formed, with one consisting of patients with OA and the other non-OA, serving as a control group. The non-OA group included individuals who had arthroscopic surgery for non-cartilage-related issues. In the OA group, all participants

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Lombardi, Alecio F., Yajun Ma, Hyungseok Jang, et al. "AcidoCEST-UTE MRI Reveals an Acidic Microenvironment in Knee Osteoarthritis." International Journal of Molecular Sciences 23, no. 8 (2022): 4466. http://dx.doi.org/10.3390/ijms23084466.

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A relationship between an acidic pH in the joints, osteoarthritis (OA), and pain has been previously demonstrated. Acidosis Chemical Exchange Saturation Transfer (acidoCEST) indirectly measures the extracellular pH through the assessment of the exchange of protons between amide groups on iodinated contrast agents and bulk water. It is possible to estimate the extracellular pH in the osteoarthritic joint using acidoCEST MRI. However, conventional MR sequences cannot image deep layers of cartilage, meniscus, ligaments, and other musculoskeletal tissues that present with short echo time and fast

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Shirinsky, I., and V. Shirinsky. "FRI0422 HOW MANY OA PATIENTS WILL BE OVERTREATED IF TREATED WITH DMOADS? ANALYSIS OF OSTEOARTHRITIS INITIATIVE DATA." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 809.1–809. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2277.

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Background:Significant research effort is currently put on discovering drugs able to slow structural progression of osteoarthritis (OA). In many patients OA shows little or no increase in pain or function deterioration over time. Thus, giving disease-modifying OA drugs (DMOAD) for long periods to this subset of patients can be considered as overtreatment. There is a lack of studies directly evaluating how many patients with diagnosed OA experience no impact of the disease during long-term follow up and thus probably do not need any disease modification.Objectives:To assess proportions of patie

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Chen, Tianwu, Shuang Wang, Yunxia Li, Chengchong Ai, Fangyi Jiang, and Shiyi Chen. "Radiographic Osteoarthritis Prevalence Over Ten Years After Anterior Cruciate Ligament Reconstruction." International Journal of Sports Medicine 40, no. 11 (2019): 683–95. http://dx.doi.org/10.1055/a-0902-8539.

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AbstractThe purpose of this study was to conduct an up-to-date systematic review and meta-analysis of radiographic knee osteoarthritis (OA) over minimal ten years after ACL reconstruction. The database of Pubmed and the Ovid was adopted. The radiographic knee OA over minimal ten years after ACL reconstruction was systematically reviewed. Both the ipsilateral and contralateral knees were evaluated referring to the tibiofemoral joint (TFJ), the patellofemoral joint (PFJ), and the overall knee OA prevalence. Nineteen studies were included for review, with nine screened for the meta-analysis. The

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Fahad, Khalid Alotaibi Sulaiman Alshammari Abdulrahman Abdulaziz Aldhubib Faisal Omar Bazuhair Abdulrahman Awad Alqahtani Abdulmalek Ibrahim Alnujid Ahmad Abdulallah Almaliki. "KNOWLEDGE, ATTITUDE AND PRACTICE TOWARDS KNEE OSTEOARTHRITIS AMONG ATHLETES IN RIYADH." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 6104–7. https://doi.org/10.5281/zenodo.2602947.

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<em>Background</em> <em>Knee Osteoarthritis is a common chronic problem; it is currently the fourth leading cause of disability worldwide, loss of work and joint surgery. Increased risk of osteoarthritis has been found among active athletes in various kinds of sports. The occurrence of knee osteoarthritis between athletes is greater than in the non-athletic individuals. Methods: A cross-sectional study was conducted through a self-administered questionnaire on athlete for both Male and Female in Gyms in Riyadh, Saudi Arabia in all age’s group. Data obtained was analysed using SPSS Softwa

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Salama, Ahmed, Kamel Rahouma, and Fatma Elzahraa Mansour. "Knee osteoarthritis automatic detection using U-Net." IAES International Journal of Artificial Intelligence (IJ-AI) 13, no. 2 (2024): 2122. http://dx.doi.org/10.11591/ijai.v13.i2.pp2122-2130.

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Knee osteoarthritis or OA is one of the most common diseases that can affect the elderly and overweight people. OA is occur as the result of wear and tear and progressive loss of articular cartilage. Kellgren-Lawrence system is a common method of classifying the severity of osteoarthritis depends on knee joint width. According to Kellgren-Lawrence, knee osteoarthritis is divided into five classes; one class represents a normal knee and the others represent four levels of knee osteoarthritis. In this work, we aim to automatically detect knee OA according to the Kellgren-Lawrence classification.

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Lyu, Shaw-Ruey. "Knee health promotion and cell therapy for knee osteoarthritis." Open Access Government 40, no. 1 (2023): 170–71. http://dx.doi.org/10.56367/oag-040-10914.

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Knee health promotion and cell therapy for knee osteoarthritis Shaw-Ruey Lyu, Professor from Dalin Tzu-Chi Hospital, Tzu-Chi University, says that the knee health promotion option and cell therapy are a perfect combination for knee osteoarthritis. Knee osteoarthritis (knee OA) is commonly but mistakenly referred to as a degenerative process of the knee. The mainstream medical community has devoted uncounted resources and talents to identifying the cause of knee OA, but that effort has only produced controversial results. Consequently, sufferers of knee OA have not been able to rest, and the de

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Rohmansyah, Nur Azis, Sumarjo, and Ashira Hiruntrakul. "Physical Activity for Osteoarthritis: A Cross-Sectional Study." Physical Education Theory and Methodology 23, no. 3 (2023): 319–24. http://dx.doi.org/10.17309/tmfv.2023.3.01.

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Background. Physical activity is a fundamental and proactive form of conservative treatment for persons with knee osteoarthritis. Study purpose. This study aims to investigate risk variables for individuals in Indonesia who had knee osteoarthritis (OA). Materials and methods. This study’s cross-sectional study design employed an observational analytical approach. The samples obtained using Slovin’s formula contained as many as 66 respondents. The study’s dependent variables were the primary and secondary types of knee OA. Results. The study’s dependent variables were the primary and secondary

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Sikander, Tanveer, Muhammad Haris Raza, Ahsaan Ullah, et al. "Association Between Occurrence of Knee Osteoarthritis and Physical Activity in Older Adults." Journal of Health and Rehabilitation Research 4, no. 1 (2024): 764–68. http://dx.doi.org/10.61919/jhrr.v4i1.408.

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Background: Knee osteoarthritis (OA) is a leading cause of disability among older adults, significantly affecting their quality of life and mobility. The relationship between physical activity and the severity of knee OA symptoms has been a subject of extensive research, with mixed results on whether physical activity exacerbates or alleviates OA symptoms. Objective: This study aimed to investigate the association between physical activity levels and the severity of knee osteoarthritis, as well as to assess the impact of physical activity on the health-related quality of life among individuals

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Mersiha Cerkezovic, Denijal Tulumović, Selmira Brkić, and Elvedin Osmanovic. "The association of osteoarthritis with metabolic disorders." Magna Scientia Advanced Research and Reviews 12, no. 1 (2024): 110–21. http://dx.doi.org/10.30574/msarr.2024.12.1.0158.

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Osteoarthritis (OA) is the most common form of synovial joint arthritis that causes chronic pain and disability to a large number of people worldwide. Most often, osteoarthritis affects the joints of the knees, hips, spine and hands. The Global Burden of Disease (GBD, 2021) estimates that osteoarthritis will be the fourth leading cause of disability by 2030, with enormous healthcare costs for treatment, as well as significant indirect costs due to loss of productivity and premature retirement. The aim of our research is to determine in what way prevalent metabolic syndrome is among participant

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Lee, J., Y. Eun, I. Y. Kim, et al. "FRI0540 DIFFERENT ASSOCIATION BETWEEN BONE MINERAL DENSITY AND OSTEOARTHRITIS ACCORDING TO THE SITE OF OSTEOARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 871.1–871. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5170.

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Background:Osteoarthritis (OA) and osteoporosis (OP) are both high prevalence at old age, and there are various reports on the association between the two diseases. Some studies have shown that high bone mineral density (BMD) is a risk factor for OA incidence, while others have mentioned the possibility of OP contributing to onset of hip OA. Recent study described that higher BMD reduce the risk of hip OA and raise the risk of knee OA. So, the relationship between BMD and OA or the effects of BMD on different OA site are not clear yet.Objectives:In this study, we investigated the association b

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Ahmed, Salama Abdellatif, Hussien Rahouma Kamel, and E. Mansour Fatma. "Knee osteoarthritis automatic detection using U-Net." IAES International Journal of Artificial Intelligence (IJ-AI) 13, no. 2 (2024): 2122–30. https://doi.org/10.11591/ijai.v13.i2.pp2122-2130.

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Knee osteoarthritis or OA is one of the most common diseases that can affect the elderly and overweight people. OA is occurred as the result of wear, tear, and progressive loss of articular cartilage. Kellgren-Lawrence system is a common method of classifying the severity of osteoarthritis depends on knee joint width. According to Kellgren-Lawrence, knee OA is divided into five classes; one class represents a normal knee and the others represent four levels of knee OA. In this work, we aim to automatically detect knee OA according to the Kellgren-Lawrence classification. The proposed system us

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Novakov, Vitaly B., Olga N. Novakova, and Mikhail I. Churnosov. "Genome-wide Studies of knee Osteoarthritis: Review." Traumatology and Orthopedics of Russia 27, no. 4 (2021): 131–44. http://dx.doi.org/10.21823/2311-2905-2021-27-1580.

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Background. Knee osteoarthritis (OA) is a multifactorial disease resulting from the interaction of many environmental, epigenetic and genetic risk factors, and the latter account for 40% to 65%. Genetic bases of the knee OA based on genome-wide association study (GWAS) are being actively studied by many scientific teams around the world. At the same time, the results obtained are often contradictory and ambiguous, as for the conducted replicative studies of knee OA. This dictates the need for additional replicative studies in various populations, including populations of Russia. The aim of the

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Fitriati, Ratih. "Osteoarthritis." KESANS : International Journal of Health and Science 1, no. 4 (2022): 415–21. http://dx.doi.org/10.54543/kesans.v1i4.42.

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Osteoarthritis (OA) is the most common joint disorder in the community and is chronic in nature and is the most common joint disease in adults to the elderly worldwide. The disease most commonly affects the joints in the knees, hands, feet, and spine and is relatively common in the shoulder and hip joints. The diagnosis of OA was made on the basis of appropriate radiological and clinical findings. The most common predilection for OA is the lower extremities, namely the knees and hips so that OA is the most common cause of lower extremity disability in the elderly. Method: The method used in wr

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ALLEN, KELLI D., JIU-CHIUAN CHEN, LEIGH F. CALLAHAN, et al. "Associations of Occupational Tasks with Knee and Hip Osteoarthritis: The Johnston County Osteoarthritis Project." Journal of Rheumatology 37, no. 4 (2010): 842–50. http://dx.doi.org/10.3899/jrheum.090302.

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Objective.This cross-sectional study examined associations of occupational tasks with radiographic and symptomatic osteoarthritis (OA) in a community-based sample.Methods.Participants from the Johnston County Osteoarthritis Project (n = 2729) self-reported the frequency of performing 10 specific occupational tasks at the longest job ever held (never/seldom/sometimes vs often/always) and lifetime exposure to jobs that required spending > 50% of their time doing 5 specific tasks or lifting 22, 44, or 110 pounds 10 times weekly. Multivariable logistic regression models examined associations of

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Korochina, K., T. Chernysheva, I. Korochina, V. Klementeva, and G. Kuznetsov. "AB0582 KNEE OSTEOARTHRITIS PHENOTYPES STRATIFICATION." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1328.1–1329. http://dx.doi.org/10.1136/annrheumdis-2021-eular.36.

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Background:Osteoarthritis (OA) relevance is determined by its record prevalence with progredient growth throughout the world [1]. Clinical and pathogenic heterogeneity of disease actualizes problem of its stratification [2]. Lack of unified understanding of OA and its phenotype determination results in incredible number of attempts to group OA, using of different classification criteria in last decade.Objectives:To analyze and systematize available OA classifications, proposals and phenotypes, to highlight the most promising of them.Methods:We studied publications from MEDLINE / PubMed and Goo

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Ekeland, Arne, Tor Kjetil Nerhus, Sigbjørn Dimmen, and Stig Heir. "Better functional results of opening wedge HTO for varus knees with medial osteoarthritis than opening wedge LFO for valgus knees with lateral osteoarthritis." Bone & Joint Open 1, no. 7 (2020): 346–54. http://dx.doi.org/10.1302/2046-3758.17.bjo-2020-0081.r1.

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Aims To compare time dependent functional improvement for patients with medial, respectively lateral knee osteoarthritis (OA) after treatment with opening wedge osteotomy relieving the pressure on the osteoarthritic part of the knee. Methods In all, 49 patients (52 knees) with a mean age of 47 years (31 to 64) underwent high tibial osteotomies (HTO), and 24 patients with a mean age of 48 years (31 to 62) low femoral osteotomies (LFO) with opening wedge technique due to medial, respectively lateral knee OA with malalignment. All osteotomies were stabilized with a Puddu plate and bone grafting p

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Ekeland, Arne, Tor Kjetil Nerhus, Sigbjørn Dimmen, and Stig Heir. "Better functional results of opening wedge HTO for varus knees with medial osteoarthritis than opening wedge LFO for valgus knees with lateral osteoarthritis." Bone & Joint Open 1, no. 7 (2020): 346–54. http://dx.doi.org/10.1302/2633-1462.17.bjo-2020-0081.r1.

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Aims To compare time dependent functional improvement for patients with medial, respectively lateral knee osteoarthritis (OA) after treatment with opening wedge osteotomy relieving the pressure on the osteoarthritic part of the knee. Methods In all, 49 patients (52 knees) with a mean age of 47 years (31 to 64) underwent high tibial osteotomies (HTO), and 24 patients with a mean age of 48 years (31 to 62) low femoral osteotomies (LFO) with opening wedge technique due to medial, respectively lateral knee OA with malalignment. All osteotomies were stabilized with a Puddu plate and bone grafting p

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De Marziani, Luca, Angelo Boffa, Simone Orazi, et al. "Joint Response to Exercise Is Affected by Knee Osteoarthritis: An Infrared Thermography Analysis." Journal of Clinical Medicine 12, no. 10 (2023): 3399. http://dx.doi.org/10.3390/jcm12103399.

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Infrared thermography can be used to evaluate the inflammation characterizing the joint environment of OA knees, but there is limited evidence on the response to physical exercise. Identifying the response to exercise of OA knees and the influencing variables could provide important information to better profile patients with different knee OA patterns. Sixty consecutive patients (38 men/22 women, 61.4 ± 9.2 years) with symptomatic knee OA were enrolled. Patients were evaluated with a standardized protocol using a thermographic camera (FLIR-T1020) positioned at 1 m with image acquisition of an

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Jacobs, Cale A., Ana-Maria Vranceanu, Katherine L. Thompson, and Christian Lattermann. "Rapid Progression of Knee Pain and Osteoarthritis Biomarkers Greatest for Patients with Combined Obesity and Depression: Data from the Osteoarthritis Initiative." CARTILAGE 11, no. 1 (2018): 38–46. http://dx.doi.org/10.1177/1947603518777577.

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Objective To compare the progression of biochemical biomarkers of osteoarthritis (OA), knee pain, and function between nonobese patients (NON), obese patients without depression (OBESE), and obese patients with comorbid depression (O + D). Design Utilizing the FNIH OA Biomarkers Consortium dataset, we categorized knee OA patients into NON, OBESE, and O + D groups based on body mass index and Center for Epidemiological Studies–Depression (CES-D) scores. Subjective symptoms (Knee injury and Osteoarthritis Outcome Score Quality of Life subscale (KOOS QOL), Western Ontario and McMaster Universitie

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Riddle, Daniel L., and Mateusz Makowski. "Knee Pain Patterns and Associations with Pain and Function in Persons with or at Risk for Symptomatic Radiographic Osteoarthritis: A Cross-sectional Analysis." Journal of Rheumatology 42, no. 12 (2015): 2398–403. http://dx.doi.org/10.3899/jrheum.150545.

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Objective.Knee pain location is routinely assessed in clinical practice. We determined the patterns of patient-reported pain locations for persons with knee osteoarthritis (OA). We also examined associations between knee pain patterns and severity of self-reported pain with activity and self-reported functional status.Methods.The Osteoarthritis Initiative data were used to examine reports of pain location (localized, regional, or global) and type and extent of knee OA. Multivariable ANCOVA models were used to determine associations between the Knee Injury and Osteoarthritis Outcome Survey (KOO

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Smith, Matthew V., Jeffrey J. Nepple, Rick W. Wright, Matthew J. Matava, and Robert H. Brophy. "Knee Osteoarthritis Is Associated With Previous Meniscus and Anterior Cruciate Ligament Surgery Among Elite College American Football Athletes." Sports Health: A Multidisciplinary Approach 9, no. 3 (2016): 247–51. http://dx.doi.org/10.1177/1941738116683146.

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Background: Football puts athletes at risk for knee injuries such meniscus and anterior cruciate ligament (ACL) tears, which are associated with the development of osteoarthritis (OA). Previous knee surgery, player position, and body mass index (BMI) may be associated with knee OA. Hypothesis: In elite football players undergoing knee magnetic resonance imaging at the National Football League’s Invitational Combine, the prevalence of knee OA is associated with previous knee surgery and BMI. Study Design: Retrospective cohort. Level of Evidence: Level 4. Methods: A retrospective review was perf

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Bishop, Aaron, and Denise Rizzolo. "Orthobiologics and the Treatment of Knee Osteoarthritis." JBJS Journal of Orthopaedics for Physician Assistants 12, no. 2 (2024): e24.00002. http://dx.doi.org/10.2106/jbjs.jopa.24.00002.

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Knee osteoarthritis (OA) has a detrimental effect on millions of patients in the United States. Although many clinicians are familiar with multiple treatments for knee arthritis, orthobiologics are not frequently part of the conversation for the treatment of knee OA. Orthobiologics involves the usage of natural substances to treat musculoskeletal conditions including knee OA.

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Puthuru Kavya, Kouluri Sreeja Reddy, Tholla Ujwala, Amuru Mounitha, and Ms. Rekha M S. "Knee Osteoarthritis Detection and It’s Severity CNN." International Journal of Scientific Research in Computer Science, Engineering and Information Technology 10, no. 3 (2024): 173–78. http://dx.doi.org/10.32628/cseit2410322.

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Osteoarthritis (OA) of the knee is a common degenerative joint disease that is characterized by inflammation and cartilage degradation, which results in pain and impairment. For prompt intervention and care, early detection and precise assessment of the severity of OA are essential. In this research, we offer a unique method for automated knee OA diagnosis and severity assessment using medical imaging data, especially X-ray images, using convolutional neural networks (CNNs). Our CNN architecture is intended to identify complex features from knee X-rays and categorize them into various OA sever

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Oei, Edwin H. G., Tijmen A. van Zadelhoff, Susanne M. Eijgenraam, Stefan Klein, Jukka Hirvasniemi, and Rianne A. van der Heijden. "3D MRI in Osteoarthritis." Seminars in Musculoskeletal Radiology 25, no. 03 (2021): 468–79. http://dx.doi.org/10.1055/s-0041-1730911.

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AbstractOsteoarthritis (OA) is among the top 10 burdensome diseases, with the knee the most affected joint. Magnetic resonance imaging (MRI) allows whole-knee assessment, making it ideally suited for imaging OA, considered a multitissue disease. Three-dimensional (3D) MRI enables the comprehensive assessment of OA, including quantitative morphometry of various joint tissues. Manual tissue segmentation on 3D MRI is challenging but may be overcome by advanced automated image analysis methods including artificial intelligence (AI). This review presents examples of the utility of 3D MRI for knee O

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Degala, Ravi Prakash. "Comprehensive Management of Knee Osteoarthritis." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 04 (2025): 1–9. https://doi.org/10.55041/ijsrem46624.

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Abstract Knee osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by progressive cartilage loss, chronic pain, and functional impairment. Effective management requires a multifaceted approach tailored to the disease stage, symptom severity, and individual patient needs. This review provides a comprehensive overview of current evidence-based strategies for managing knee OA, encompassing non-pharmacologic, pharmacologic, and surgical interventions. Non-pharmacologic treatments, including patient education, physical therapy, and weight management, form the cornerstone of

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Ahmad, Rusul Sheet, and Bashar Jassim Al-Jwary. "Impact of Lifestyle on Knee Osteoarthritis in Mosul Hospitals." Pakistan Journal of Medical and Health Sciences 17, no. 4 (2023): 638–41. http://dx.doi.org/10.53350/pjmhs2023174638.

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Background & Objectives: Osteoarthritis (OA) is the most prevalent form of arthritis. It is a chronic, degenerative disease of the musculoskeletal system that causes significant disability in patients all over the world. The knee is the most commonly affected joint by OA, especially in older people. Knee OA is a painful disorder that progresses with time and affects the whole knee joint, leading to varying degrees of severe joint failure. It can cause pain, stiffness, and swelling in the knee. It can also lead to disability ,and Lifestyle factors were found to be related to knee OA. This s

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