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Journal articles on the topic 'Knowledge of POZ patients'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Chang, Zhi, Jiwen Shang, Shushang Yang, Wuyao Qin, and Hao Cui. "Co-occurrence of pheochromocytoma and paraganglioma of the organ of Zuckerkandl resected simultaneously by laparoscopy: a rare case report and literature review." Journal of International Medical Research 51, no. 3 (2023): 030006052311612. http://dx.doi.org/10.1177/03000605231161211.

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Pheochromocytomas (PHEOs) and paragangliomas are generally grouped as rare chromaffin cell tumors. The co-occurrence of PHEOs and paragangliomas of the organ of Zuckerkandl (POZ) is extremely rare. The most common symptom of pheochromocytoma-paraganglioma (PPGL) is hypertension, and open surgery is still recommended for the treatment of large PPGLs. Herein, we report a case of a successful simultaneous laparoscopic resection of a large PHEO accompanied by POZ in a 40-year-old man with normal blood pressure. DNA analysis revealed a mutation in the succinate dehydrogenase subunit B in both the P

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Richman, Alice R., Janice P. Tzeng, Lisa A. Carey, Valesca P. Retèl, and Noel T. Brewer. "Knowledge of genomic testing among early-stage breast cancer patients." Psycho-Oncology 20, no. 1 (2010): 28–35. http://dx.doi.org/10.1002/pon.1699.

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Kállay, Éva, Sebastian Pintea, and Csaba L. Dégi. "Does knowledge of diagnosis really affect rates of depression in cancer patients?" Psycho-Oncology 25, no. 12 (2016): 1418–23. http://dx.doi.org/10.1002/pon.4073.

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Fischer, Katrina, Anne Margaret Walling, and John A. Glaspy. "Factors associated with physician attitude and management of financial toxicity." Journal of Clinical Oncology 37, no. 15_suppl (2019): e18300-e18300. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18300.

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e18300 Background: Little is known about the attitudes and knowledge of oncologists who discuss financial toxicity with patients compared with those who do not. We assessed perceptions of the oncologists’ role in discussing out of pocket (OOP) costs and financial stress (FS) to inform quality improvement strategies in the management of financial toxicity. Methods: We surveyed 45 practicing medical oncologists at a large academic medical center in 2019 using Likert scale responses. Questions covered three domains; self-perceived knowledge of financial issues related to care, practice of cost di

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Šoukalová, Kristýna, Martin Prázný, and Barbora Doležalová. "Development and evaluation of content validity knowledge questionnaire for patients with diabetes mellitus." Profese online 10, no. 1 (2017): 8–14. http://dx.doi.org/10.5507/pol.2017.002.

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Borgmann‐Staudt, Anja, Marina Kunstreich, Ralph Schilling, et al. "Fertility knowledge and associated empowerment following an educational intervention for adolescent cancer patients." Psycho-Oncology 28, no. 11 (2019): 2218–25. http://dx.doi.org/10.1002/pon.5210.

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Njoroge, George, Lucy Kivuti-Bitok, and Samuel Kimani. "Preoperative Fasting among Adult Patients for Elective Surgery in a Kenyan Referral Hospital." International Scholarly Research Notices 2017 (April 12, 2017): 1–8. http://dx.doi.org/10.1155/2017/2159606.

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Background. Preoperative fasting (POF) is physiologically and precautionary important during anesthesia and surgery. POF from midnight has been practiced despite the recommended shorter practice. Objective. Assessing preoperative fasting among adult patients scheduled for elective surgery at Kenyatta National Hospital (KNH). Methods. A descriptive cross-sectional study involving 65 surgical patients. A questionnaire of mixed questions on demographics, reasons, source of instructions, opinion on instructions, time, premedication practices, outcome, and complains on NPO was used. Analysis was qu

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Tesch, Megan, Noah Graham, Sean Ryan, et al. "Abstract PO1-03-08: Association of patient-reported triple-negative breast cancer (TNBC) knowledge with clinical trial participation." Cancer Research 84, no. 9_Supplement (2024): PO1–03–08—PO1–03–08. http://dx.doi.org/10.1158/1538-7445.sabcs23-po1-03-08.

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Abstract Background: Patients with TNBC are highly encouraged to participate in clinical trials given the lack of targeted treatment options for this breast cancer subtype. Yet little is known regarding barriers to trial participation in this population, including the impact of patients’ understanding about TNBC biology. We examined whether disease knowledge and other patient-level factors were associated with TNBC patients’ participation in trials. Methods: From a multicenter, prospective cohort study of patients enrolled from 2019-present with newly diagnosed TNBC (ER/PR ≤10% also eligible),

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Sternal, Danuta, Grażyna Franek, and Dorota Pieńkus. "Knowledge of Nurses on Prevention of Nosocomial Infections in post-stroke Patients." Journal of Neurological and Neurosurgical Nursing 3, no. 2 (2014): 58–63. http://dx.doi.org/10.15225/pnn.2014.3.2.2.

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10

Bustami, Bustami, Abdurrahman Abdurrahman, and Amiruddin Amiruddin. "The Role of Nurse Education in Enhancing Knowledge and Skills of Diabetes Management in Patients." Path of Science 9, no. 7 (2023): 2050–58. http://dx.doi.org/10.22178/pos.94-9.

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11

Anderson, Eric C., John DiPalazzo, Emily Edelman, et al. "Patients' Expectations of Benefits From Large-Panel Genomic Tumor Testing in Rural Community Oncology Practices." JCO Precision Oncology, no. 5 (September 2021): 1554–62. http://dx.doi.org/10.1200/po.21.00235.

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PURPOSE Large-panel genomic tumor testing (GTT) is an emerging technology that promises to make cancer treatment more precise. Because GTT is novel and complex, patients may have unrealistic expectations and limited knowledge of its benefits. These problems may limit the clinical value of GTT, but their prevalence and associated factors have not been explored. METHODS Patients with cancer enrolled in a large initiative to disseminate GTT in community oncology practices completed surveys assessing their expectations, knowledge, and attitudes about GTT. The study sample (N = 1,139) consisted of

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Koulentaki, M., E. Orfanoudaki, D. Samonakis, et al. "PO4-8GENERAL KNOWLEDGE ON ALCOHOL AND ALCOHOL USE IN A COHORT OF CRETAN LIVER DISEASE PATIENTS." Alcohol and Alcoholism 52, suppl_1 (2017): i31—i49. http://dx.doi.org/10.1093/alcalc/agx074.52.

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13

Murasse, Luisa Saemi, and Uiara Raiana Vargas de Castro Oliveira Ribeiro. "Advance directive of will: knowledge and use by resident physicians." Revista Bioética 30, no. 3 (2022): 598–609. http://dx.doi.org/10.1590/1983-80422022303553en.

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Abstract Care planning based on advance directives is vital to preserve the autonomy and dignity of patients. In view of this, this study sought to verify the level of knowledge of medical residents of Curitiba, Paraná, Brazil, about them and their use in clinical practice. The feeling of these professionals regarding their knowledge and safety about the instrument was also evaluated. A quantitative and cross-sectional research was carried out by applying a structured questionnaire on a digital platform with a final sample of 45 participants. The results indicate that the knowledge of these pr

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Völler, Heinz, Uwe Taborski, Clemens Dovifat, et al. "ProTime self-management yielding improvement of fluency and quality of life." Thrombosis and Haemostasis 98, no. 10 (2007): 889–95. http://dx.doi.org/10.1160/th07-02-0143.

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SummaryPatient self-management (PSM), as the standard of care for vitamin K-antagonist therapy management in Germany requires a detailed, point-of-care (POC) device-specific training program to ensure quality patient care. In a multi-center trial using the ProTime System (Training program plus POC device), 105 patients were enrolled to evaluate efficacy of training, knowledge retention, patient satisfaction and quality of life (QoL). Patients returned to the centers 1, 3 and 6 months after training to complete questionnaires and demonstrate INR test proficiency. Training assessment employed se

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Szafraniec-buryło, Sylwia, Artur Prusaczyk, and Sabina Karczmarz. "Place of Primary Care operating within the framework of integrated care in the pathway of comprehensive genetic care." International Journal of Integrated Care 25 (April 9, 2025): 637. https://doi.org/10.5334/ijic.icic24526.

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Background: The aim of this abstract is to describe the pathway of comprehensive genetic care, including the process of stratification, examinations, and the development and implementation of a patient care plan, enabling the integration of personalized medicine advancements. Methods: Since 2008, the Medical Diagnostic Center in Siedlce, Poland has implemented the Health Status Assessment as part of integrated primary care pathway. This involves updating the medical history, determining participation in preventive examinations, and identifying fundamental symptoms that may serve as indicators

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Calle, Soledad, and Virgina Troche. "Cognitive and Technical Competencies of Nursing Professionals in the Application of the Mnemonic Fast - Hug - Bid "Quick Hug"." International Journal of Critical Care 18, no. 4 (2024): 5. https://doi.org/10.29173/ijcc1021.

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Background: The FAST-HUG-BID mnemonic is a checklist designed for critically ill patients. Aim: To determine the cognitive and technical competencies of nursing professionals in the application of the FAST-HUG-BID "Quick Hug" mnemonic applied to patients in Critical Care Units of the Private Banking Health Fund in La Paz. Methodology: This research was organized using a cross-sectional study. Data collection took place during the first semester of 2022. The study area was the Private Banking Health Fund, Obrajes Zone in the City of La Paz. Results: More than 75% have 5 or more years of work ex

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Slováček, Ladislav. "Quality of life in patients after transplation of hemopoietic cells: current knowledge from selected foreing trials." Kontakt 7, no. 1-2 (2005): 9–16. http://dx.doi.org/10.32725/kont.2005.003.

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Pallarz, Steffen, Manuela Benary, Mario Lamping, et al. "Comparative Analysis of Public Knowledge Bases for Precision Oncology." JCO Precision Oncology, no. 3 (December 2019): 1–8. http://dx.doi.org/10.1200/po.18.00371.

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PURPOSE Precision oncology depends on the availability of up-to-date, comprehensive, and accurate information about associations between genetic variants and therapeutic options. Recently, a number of knowledge bases (KBs) have been developed that gather such information on the basis of expert curation of the scientific literature. We performed a quantitative and qualitative comparison of Clinical Interpretations of Variants in Cancer, OncoKB, Cancer Gene Census, Database of Curated Mutations, CGI Biomarkers (the cancer genome interpreter biomarker database), Tumor Alterations Relevant for Gen

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Ferenčík, N., R. Hudák, M. Kohan, and V. Rajťúková. "Pros and Cons of Computer-Assisted Rehabilitation." Uniciencia 36, no. 1 (2022): 1–7. https://doi.org/10.15359/ru.36-1.27.

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This article summarized the knowledge obtained from exercises with patients using computer-assisted rehabilitation. Working with a wide base of healthy individuals and patients with various problems yielded the results to summarize. This work utilized several rehabilitation devices using computer games and uncovered positive and negative aspects of contemporary rehabilitation procedures. we conclude in this research computer-assisted rehabilitation is the future of modern rehabilitation, so it is necessary to know all factors affecting patients’ health.

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Schagen, Sanne B., Enny Das, and Frits S. A. M. van Dam. "The influence of priming and pre-existing knowledge of chemotherapy-associated cognitive complaints on the reporting of such complaints in breast cancer patients." Psycho-Oncology 18, no. 6 (2008): 674–78. http://dx.doi.org/10.1002/pon.1454.

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Melnick, Ari, K. Farid Ahmad, Sally Arai, et al. "In-Depth Mutational Analysis of the Promyelocytic Leukemia Zinc Finger BTB/POZ Domain Reveals Motifs and Residues Required for Biological and Transcriptional Functions." Molecular and Cellular Biology 20, no. 17 (2000): 6550–67. http://dx.doi.org/10.1128/mcb.20.17.6550-6567.2000.

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ABSTRACT The promyelocytic leukemia zinc finger (PLZF) protein is a transcription factor disrupted in patients with t(11;17)(q23;q21)-associated acute promyelocytic leukemia. PLZF contains an N-terminal BTB/POZ domain which is required for dimerization, transcriptional repression, formation of high-molecular-weight DNA-protein complexes, nuclear sublocalization, and growth suppression. X-ray crystallographic data show that the PLZF BTB/POZ domain forms an obligate homodimer via an extensive interface. In addition, the dimer possesses several highly conserved features, including a charged pocke

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Lee, Hyungmook, Jeongmin Kim, Ki-Young Lee, et al. "Awareness and Perspectives among Asian Anesthesiologists on Postoperative Delirium: A Multinational Survey." Journal of Clinical Medicine 10, no. 24 (2021): 5769. http://dx.doi.org/10.3390/jcm10245769.

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Postoperative delirium (POD) is a common perioperative complication. Although POD is preventable in up to 40% of patients, it is frequently overlooked. The objective of the survey is to determine the level of knowledge and clinical practices related to POD among anesthesiologists in different Asian countries. A questionnaire of 22 questions was designed by members of the Asian focus group for the study of POD, and it was sent to anesthesiologists in Singapore, Thailand, and South Korea from 1 April 2019 through 17 September 2019. In total, 531 anesthesiologists (Singapore: 224, Thailand: 124,

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Jovanović, Vesna, Nebojša Lađević, and Sandra Šipetić-Grujičić. "Risk factors for the occurrence of postoperative delirium." Zdravstvena zastita 52, no. 4 (2023): 20–35. http://dx.doi.org/10.5937/zdravzast52-47258.

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The occurrence of postoperative delirium (POD) has been recognized in recent decades as an important clinical syndrome, especially in elderly patients undergoing surgical treatment. The aim of this review was to examine the preoperative, intraoperative and postoperative factors that can lead to the occurrence of POD. The risk factors for developing POD are numerous, and most importantly, many can be modified. Some of the most significant risk factors for the occurrence of POD are older age, alcohol abuse, preoperatively worse functional and cognitive status, presence of depression and dementia

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Bi, Xiaobo, Jingxia Wei, and Xia Zhang. "Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis." Journal of International Medical Research 49, no. 5 (2021): 030006052110142. http://dx.doi.org/10.1177/03000605211014294.

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Objective Senile patients often experience neurocognitive disturbance after non-cardiac surgery. Several clinical trials have investigated if the perioperative intravenous use of dexmedetomidine has a positive effect on the prevention of neurocognitive dysfunction, but the results have been inconsistent. We performed a meta-analysis to investigate the effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients. Methods The PubMed, Cochrane Library, EMBASE and China National Knowledge Infrastructure databases were comprehensively searched for a

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Hamilton, Jada G., Jessica M. Long, Amanda C. Brandt, et al. "Patients’ Medical and Psychosocial Experiences After Detection of a CDH1 Variant With Multigene Panel Testing." JCO Precision Oncology, no. 3 (December 2019): 1–14. http://dx.doi.org/10.1200/po.18.00300.

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PURPOSE Germline CDH1 pathogenic variants (PV) are associated with hereditary diffuse gastric cancer and lobular breast cancer. Although prevalence of CDH1 PV is low in the general population, detection of these variants is increasing with the growing use of multigene panel testing. Little is known about the experiences of individuals tested for CDH1 variants in the multigene panel testing era. METHODS Participants recruited from the Prospective Registry of Multiplex Testing completed a cross-sectional self-report survey regarding CDH1 genetic testing experiences, medical management, and psych

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Liu, Jing, and Yue-Qiao Gao. "Myocardial Edema: A Rare but Specific Manifestation of Neonatal Capillary Leak Syndrome." Diagnostics 13, no. 23 (2023): 3597. http://dx.doi.org/10.3390/diagnostics13233597.

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Capillary leak syndrome (CLS) is a rare, potentially life-threatening systemic disease with a mortality rate of more than 30%. Its major clinical manifestation and diagnostic basis are systemic hyperedema. However, we lack knowledge about the presence of severe myocardial edema in patients with CLS. If myocardial edema cannot be detected, it will become a dangerous hidden condition that threatens the safety of patient lives. With the routine application of point-of-care critical ultrasound (POC-CUS) in clinical practice, we found that 2 of 37 (5.41%) CLS patients had severe myocardial edema as

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Alizai, Shehla Ambreen, Lubna Ehtizaz, Ambreen Ansar, Saba Khilji, Maleeha Saad, and Ayesha Ali. "Pre-analytical Quality Assurance; An Important Milestone to be Achieved." Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University 13, no. 4 (2024): 404–9. http://dx.doi.org/10.48036/apims.v13i4.896.

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Objective: To assess the knowledge of junior doctors and nurses about proper collection, storage and dispatch of pathology specimens to the laboratory. Methodology: This was a cross sectional questionnaire-based study conducted at Dr. Akbar Niazi Teaching Hospital (DANTH), Islamabad and Pakistan Ordinance factories (POF) Hospital Wah from Jan-June 2023. Hard copy of questionnaire with 29 questions regarding sample collection related to Hematology, Microbiology, Chemical pathology and Histopathology was given to junior doctors and nurses. Total 171 responses were received from junior doctors an

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Skalski, Joseph H., Muhamad Elrashidi, Darcy A. Reed, Furman S. McDonald, and Anjali Bhagra. "Using Standardized Patients to Teach Point-of-Care Ultrasound-Guided Physical Examination Skills to Internal Medicine Residents." Journal of Graduate Medical Education 7, no. 1 (2015): 95–97. http://dx.doi.org/10.4300/jgme-d-14-00178.1.

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Abstract Background Point-of-care (POC) ultrasound has been shown to improve procedural outcomes and physical examination accuracy in multiple settings. There are limited data regarding the optimal way to train nonradiologists in POC ultrasound. This is a primary barrier to more widespread use of ultrasound in the physical examination. Objective We created a workshop to instruct postgraduate year (PGY)-2 and PGY-3 internal medicine residents in POC ultrasound imaging of the abdominal aorta and kidneys. Methods A half-day simulation center workshop was created to review ultrasound operations an

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Stover, Daniel, Deloris Veney, Lai Wei, et al. "Abstract PO1-10-07: A Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients with Metastatic Breast Cancer: Primary Results of a Prospective Intervention Trial." Cancer Research 84, no. 9_Supplement (2024): PO1–10–07—PO1–10–07. http://dx.doi.org/10.1158/1538-7445.sabcs23-po1-10-07.

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Abstract Background: Tumor genomic testing (TGT) has become standard-of-care for all patients with metastatic breast cancer (MBC). American Society of Clinical Oncology (ASCO) and American College of Medical Genetics (ACMG) guidelines for patient education prior to TGT are not widely followed. We have previously demonstrated disparities in general genomic knowledge across race and income. The purpose of this study was to develop a concise (3-4 minute) video for patient education prior to TGT and evaluate the video’s impact in a prospective interventional trial. We report the results of the pri

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Demeestere, Isabelle, Pauline Brice, Fedro A. Peccatori, et al. "No Evidence for the Benefit of Gonadotropin-Releasing Hormone Agonist in Preserving Ovarian Function and Fertility in Lymphoma Survivors Treated With Chemotherapy: Final Long-Term Report of a Prospective Randomized Trial." Journal of Clinical Oncology 34, no. 22 (2016): 2568–74. http://dx.doi.org/10.1200/jco.2015.65.8864.

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Purpose We have reported previously that after 1-year follow up, gonadotropin-releasing hormone agonist (GnRHa) did not prevent chemotherapy-induced premature ovarian failure (POF) in patients with lymphoma, but may provide protection of the ovarian reserve. Here, we report the final analysis of the cohort after 5 years of follow up. Patients and Methods A total of 129 patients with lymphoma were randomly assigned to receive either triptorelin plus norethisterone (GnRHa group) or norethisterone alone (control group) during chemotherapy. Ovarian function and fertility were reported after 2, 3,

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Arakaki, Lorilee S. L., Wayne A. Ciesielski, D. Michael McMullan, and Kenneth A. Schenkman. "Noninvasive Cellular Oxygenation Measurement During Graded Hypoxia Using Visible–Near-Infrared Spectroscopy." Applied Spectroscopy 74, no. 10 (2020): 1263–73. http://dx.doi.org/10.1177/0003702820938867.

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In critically ill patients, direct knowledge of intracellular pO2 would allow for identification of cellular hypoxia, which when prolonged leads to organ failure. We have developed a visible–near-infrared optical system that noninvasively measures myoglobin saturation, which is directly related to intracellular pO2, from the surface of the skin. We used an animal model of graded hypoxia from low levels of inspired oxygen ( n = 5) and verified that low intracellular pO2 is correlated with high steady-state serum lactate values. In addition, the pO2 gradient between arterial blood and inside mus

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Souza Júnior, José Roberto de, Pedro Henrique Reis Rabelo, Thiago Vilela Lemos, Glauber Marques Paraizo Barbosa, and João Paulo Chieregato Matheus. "Knowledge, interest, and preference for gait retraining programs in street runners: a cross-sectional study." Fisioterapia e Pesquisa 29, no. 1 (2022): 68–73. http://dx.doi.org/10.1590/1809-2950/21016929012022en.

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ABSTRACT Some treatment modalities have been used to prevent or treat running-related musculoskeletal injuries, among them, gait retraining. This study aimed to evaluate street runners’ knowledge, interest, and preference for gait retraining programs and assess if these aspects differ between runners with and without history of injury. This is a cross-sectional study with 100 runners. Initially, a text showing what gait retraining was about was presented to participants. Then, they answered questions about their knowledge (yes x no) and interest (yes x no) on the programs. Subsequently, a text

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Dieterlen, Maja-Theresa, Hartmuth B. Bittner, Attila Tarnok, et al. "Flow Cytometric Evaluation of T Cell Activation Markers after Cardiopulmonary Bypass." Surgery Research and Practice 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/801643.

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Background. Cardiopulmonary bypass surgery (CPBS) is associated with an increased risk for infections or with subsequent organ dysfunction. As T cell activation is a central mechanism during inflammatory processes, we developed an assay to evaluate T cell activation pathways in patients undergoing CPBS.Methods. Blood was obtained from eleven patients undergoing CPBS preoperatively, on postoperative day (POD)-3, and on POD-7 and was stimulated with different concentrations of Concanavalin A (ConA). Cyclosporine and sirolimus, inhibiting different pathways of the T cell cycle, were added to bloo

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Bradbury, Angela R., Linda Patrick-Miller, Brian L. Egleston, et al. "Returning Individual Genetic Research Results to Research Participants: Uptake and Outcomes Among Patients With Breast Cancer." JCO Precision Oncology, no. 2 (November 2018): 1–24. http://dx.doi.org/10.1200/po.17.00250.

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Purpose Understanding the outcomes of returning individual genetic research results to participants is critical because some genetic variants are found to be associated with health outcomes and have become available for clinical testing. Materials and Methods BRCA1/2-negative women with early-onset breast cancer, multiple primary cancers, or a family history of breast cancer who participated in a gene discovery cancer registry were offered the opportunity to learn their individual genetic research results of 24 breast cancer susceptibility genes with a genetic counselor after predisclosure gen

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Di Bello, Francesco Di, Ernesto Di Di Mauro, Claudia Collà Collà Ruvolo, et al. "Perioperative Red Cell Line Trend Following Robot-Assisted Radical Prostatectomy for Prostate Cancer." Medicina 58, no. 11 (2022): 1520. http://dx.doi.org/10.3390/medicina58111520.

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Background and Objective: Blood loss represents a long-standing concern of radical prostatectomy (RP). This study aimed to assess how red line cell values changed following robot-assisted radical prostatectomy (RARP) for prostate cancer (PCa). Materials and Methods: The blood panels of 453 consecutive PCa patients undergoing RARP at a single tertiary academic referral center, from September 2020 to April 2022, were reviewed. Data from 363 patients with the blood panel available for the following timeframe: within seven days before surgery, six hours after surgery, and the first three postopera

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Kułaga, Katarzyna, Katarzyna Klonowska, Katarzyna Wiktorzak, et al. "Patients' health status following health check within POZ PLUS." International Journal of Integrated Care 22, S3 (2022): 461. http://dx.doi.org/10.5334/ijic.icic22243.

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Tejada, Mariella, June YiJuan Hou, Katherine D. Crew, et al. "Integration of germline multigene panel testing into breast and gynecologic oncology clinics." Journal of Clinical Oncology 39, no. 28_suppl (2021): 164. http://dx.doi.org/10.1200/jco.2020.39.28_suppl.164.

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164 Background: Germline genetic testing plays an important role in informing cancer screening and risk-reducing strategies, as well as treatment decisions with PARP inhibitors for BRCA-associated malignancies. Referrals to clinical genetics for pre-test counseling and results disclosure can be delayed due to financial and logistical barriers, which may ultimately delay clinical decision-making. Our study objective was to understand patient attitudes, knowledge, and anxiety/distress with point-of-care (POC) genetic testing in breast and gynecologic oncology clinics. Methods: We enrolled patien

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Fishler, Kristen P., Erin H. Breese, Lauren Walters-Sen, and Michelle L. McGowan. "Experiences of a Multidisciplinary Genomic Tumor Board Interpreting Risk for Underlying Germline Variants in Tumor-Only Sequencing Results." JCO Precision Oncology, no. 3 (December 2019): 1–8. http://dx.doi.org/10.1200/po.18.00216.

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PURPOSE Although analyzing germline and tumor samples concurrently provides the best opportunity for differentiating between germline and somatic mutations, tumor-only sequencing is becoming increasingly common in clinical care. The purpose of this study is to assess how a multidisciplinary genomic tumor board (MGTB) evaluated patients’ tumor-only sequencing results and made genetics referrals. With limited professional society guidance on how to manage pathogenic mutations identified via tumor-only sequencing, this study contemplates the professional knowledge and skills necessary to have rep

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Becker, Marie, Timothy Quill, Erika Hamilton, and Joyce O'Shaughnessy. "Abstract PO3-02-01: Educational Opportunities to Improve Community Healthcare Professionals’ Management of High-Risk HR-Positive/HER2-Negative Early Breast Cancer." Cancer Research 84, no. 9_Supplement (2024): PO3–02–01—PO3–02–01. http://dx.doi.org/10.1158/1538-7445.sabcs23-po3-02-01.

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Abstract Background: The treatment landscape for patients with hormone receptor–positive/HER2-negative early breast cancer (HR+/HER2- EBC) has evolved with the emergence of adjuvant CDK4/6 inhibitor therapy as a new option for patients with a high risk of disease recurrence. Adjuvant abemaciclib plus aromatase inhibitors (AIs) is guideline recommended for high clinical risk HR+ disease and reduces risk of recurrence regardless of Ki-67 expression level. Here, we examine healthcare professionals’ (HCPs’) awareness and practice regarding the use of adjuvant abemaciclib. Methods: Between November

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Delp, Simon, Wei Mei, Claudia D. Spies, et al. "Clinical practice in the management of postoperative delirium by Chinese anesthesiologists: a cross-sectional survey designed by the European Society of Anaesthesiology." Journal of International Medical Research 48, no. 6 (2020): 030006052092720. http://dx.doi.org/10.1177/0300060520927207.

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Objective In this survey, we assessed the current clinical management of postoperative delirium (POD) among Chinese anesthesiologists, after publishing the European POD guideline. Methods We administered an electronic survey, designed according to the European POD guideline. The survey was completed using mobile devices. Results In total, 1,514 respondents from China participated in the survey. Overall, 74.4% of participants reported that delirium is very important. More than 95% of participants stated that they routinely assessed POD. In total, 61.4% screened for POD using clinical observatio

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Robles-Castro, J., R. Rivera-Luna, C. Calderon-Elvir, and C. A. Leal-Leal. "Concordance and evaluation among IGCCCG and POG staging systems in pediatric germ cell tumors." Journal of Clinical Oncology 25, no. 18_suppl (2007): 20019. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.20019.

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20019 Background: The knowledge regarding treatment and prognosis of pediatric germ cell tumors has been taken from the development of these in the adult population. The object of this work was to compare the International Classification (IGCCCG) used in adults versus the POG classification used traditionally in a pediatric population. Methods: We reviewed clinical records from March 1994 through June 2003 with the diagnosis of malignant germ cell tumor of testis, retroperitoneal and mediastinum. All patients completed the treatment proposed initially with a follow up of more than 24 months. T

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Patel, Lekha, Lulu Wei, Ariel Gidon, et al. "Poor Nutritional Literacy and Relationship to Dietary Guideline Adherence in Inner-City Dialysis Patients." Current Developments in Nutrition 6, Supplement_1 (2022): 386. http://dx.doi.org/10.1093/cdn/nzac054.041.

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Abstract Objectives Poor nutritional literacy may influence understanding and adherence to dietary guidelines. We examined nutritional literacy and adherence to dietary guidelines in inner-city dialysis patients. Methods A random sample of 34 dialysis pts was interviewed regarding knowledge about dietary guidelines and 24-hr food recall was recorded and analyzed using ASA-24. Nutritional literacy was assessed using the food label questionnaire. Results Mean age was 56 ± 17, 58% (20) male, 88% (29) identified as Black, time on dialysis 64.1 ± 17.3 mos. Mean PO4 intake was 968.2 ± 111.9 mg, sodi

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Jatwani, Karan, Mahnoor Sukaina, Atulya Aman Khosla, et al. "End-of-life care preferences in patients with gallbladder cancer: Shifting patterns and disparities over two decades." Journal of Clinical Oncology 42, no. 16_suppl (2024): 12036. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.12036.

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12036 Background: Gallbladder cancer (GBC) is an aggressive malignancy with a combined survival rate of 20%. Some studies have reported less than 10 percent utilization of palliative care services in this population. Place of Death (PoD) is an important determinant of patient and caregiver preference and cost of caregiving at the end of life (EOL). We evaluate trends in PoD for patients with GBC in the U.S. from 2003 to 2020 based on the CDC WONDER (Wide-ranging Online Data for Epidemiologic Research) database. Methods: We analyzed data using the CDC WONDER database from January 01, 2003, to D

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Warner, Jeremy L., Ishaan Prasad, Makiah Bennett, et al. "SMART Cancer Navigator: A Framework for Implementing ASCO Workshop Recommendations to Enable Precision Cancer Medicine." JCO Precision Oncology, no. 2 (November 2018): 1–14. http://dx.doi.org/10.1200/po.17.00292.

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Purpose Data standards and interoperability are critical for improving care for patients with cancer. Recent efforts by ASCO include the Data Standards and Interoperability Summit in 2016, which led to the Omics and Precision Oncology and Advancing Interoperability workshops. To facilitate improved patient care, several recommendations for data sharing and standardization were made to the community. Methods To address these recommendations, we developed SMART Cancer Navigator, a Web application that uses application programming interfaces to gather clinical and genomic data from 11 public know

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Theyagarajan, K., and Young-Joon Kim. "Metal Organic Frameworks Based Wearable and Point-of-Care Electrochemical Sensors for Healthcare Monitoring." Biosensors 14, no. 10 (2024): 492. http://dx.doi.org/10.3390/bios14100492.

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The modern healthcare system strives to provide patients with more comfortable and less invasive experiences, focusing on noninvasive and painless diagnostic and treatment methods. A key priority is the early diagnosis of life-threatening diseases, which can significantly improve patient outcomes by enabling treatment at earlier stages. While most patients must undergo diagnostic procedures before beginning treatment, many existing methods are invasive, time-consuming, and inconvenient. To address these challenges, electrochemical-based wearable and point-of-care (PoC) sensing devices have eme

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Tacyildiz, Nurdan, Sonay incesoy Ozdemir, Emel Cabi Unal, Handan Dincaslan, and Gulsan Yavuz. "Barriers and solutions of long-term follow up of childhood cancer survivors in Turkey: A questionaire survey." Journal of Clinical Oncology 35, no. 15_suppl (2017): e22020-e22020. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e22020.

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e22020 Background: The population of childhood cancer survivors has grown with 80 % cure rates. Our aim was to establish the barriers of longterm followup (LTFU) in Turkey. Methods: An e-mail questionnaire survey has been sent to 33 pediatric oncology centers (POC). Questionnaire compossed of 3 sections: 1- Description of the center; yearly new patients number, follow-up period, etc. 2- Methods for follow-up of late effects Content of provided information to the families related cancer treatment & side effects & healthy life style, missing parts of LTFU 3- Transition problems of surviv

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Lundgren, Sebastian, Sofie Olsson Hau, Jacob Elebro, et al. "Mutational Landscape in Resected Periampullary Adenocarcinoma: Relationship With Morphology and Clinical Outcome." JCO Precision Oncology, no. 3 (December 2019): 1–8. http://dx.doi.org/10.1200/po.18.00323.

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PURPOSE Periampullary adenocarcinomas encompass a heterogeneous group of tumors with dismal prognosis and limited treatment options. Emerging evidence shows that tumor morphology (ie, intestinal type [I-type] or pancreatobiliary type [PB-type]) is a more relevant prognostic factor than tumor origin. Knowledge is sparse, however, on whether key mutations differ according to morphology. MATERIALS AND METHODS Next-generation sequencing was applied to assess the mutational status of 70 genes in 102 tumors from a retrospective cohort of 175 patients with resected periampullary adenocarcinoma. Brahm

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Schulte-Baukloh, Heinrich, Catarina Weiß, Sarah Weinberger, Mandy Hubatsch, Thorsten Schlomm, and Bernhard Ralla. "Real-Time Documentation of the Effect of Onabotulinumtoxin A Detrusor Injection in OAB Patients—Preliminary Results." Toxins 15, no. 1 (2022): 30. http://dx.doi.org/10.3390/toxins15010030.

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Introduction: Detrusor injection with onabotulinumtoxin A (OnabotA-DI) is an established therapy for overactive bladder (OAB). Little is known about the exact onset and course of the effect in the days after the injection therapy. By using a new type of app-controlled automated diary pod, for the first time, the precise onset of the effect of OnabotA-DI can be documented in real time. Materials and methods: Patients due for OnabotA-DI were asked to document voiding 3 days before and up to 3 weeks after therapy using the Diary Pod app. The detrusor injection was performed with onabotulinumtoxin

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Khoo, Kelvin H. P., Amanda J. Able, Timothy K. Chataway, and Jason A. Able. "Preliminary characterisation of two early meiotic wheat proteins after identification through 2D gel electrophoresis proteomics." Functional Plant Biology 39, no. 3 (2012): 222. http://dx.doi.org/10.1071/fp11253.

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Various genetic-based approaches including mutant population screens, microarray analyses, cloning and transgenesis have broadened our knowledge of gene function during meiosis in plants. Nonetheless, these genetic tools are not without inherent limitations. One alternative approach to studying plant meiosis, especially in polyploids such as Triticum aestivum L. (bread wheat), is proteomics. However, protein-based approaches using proteomics have seldom been described, with only two attempts at studying early plant meiosis reported. Here, we report the investigation of early bread wheat meiosi

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Żebrowska, Małgorzata, Edyta Medak, Małgorzata Pachuta, and Magdalena Brodowicz-Król. "Assess the knowledge level of POZ patients on the diagnosis and treatment of type 2 diabetes." July 18, 2017. https://doi.org/10.5281/zenodo.831845.

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<strong>Żebrowska Małgorzata, Medak Edyta, Pachuta Małgorzata, Brodowicz-Król</strong><strong> </strong><strong>Magdalena.</strong><strong> </strong><strong>Assess the knowledge level of POZ patients on the diagnosis and treatment of type 2 diabetes</strong><strong>. </strong><strong>Journal of Education, Health and Sport. 2017;7(7):3</strong><strong>38</strong><strong>-3</strong><strong>56</strong><strong>. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.5281/</strong><strong>zenodo.</strong><strong>831845</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/46</stron

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