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1

Patočková, Klára. "Charakterizace nápojů a doplňků stravy obsahujících kofein." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2014. http://www.nusl.cz/ntk/nusl-217065.

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This master thesis is focused on characterization of some energy drinks and formulation of their modified composition. The theoretical part was focused on summary of energy drinks and some of their natural components - guarana, goji as well as on techniques of encapsulation. In the experimental part concentrations of caffeine, vitamin C, polyphenols and carbohydrates in commercially purchased drinks was evaluated. Subsequently, three kinds of particles (particles with caffeine, particles with guarana and particles with guarana and goji) by 6 different techniques were prepared. The efficiency of encapsulation was determined by HPLC/UV-VIS (caffeine, vitamin C) and by spectrophotometry (phenolics). Stability of the particles was followed in real food and in a model physiological environment of artificial digestive juices. Size of prepared particles was determined by dynamic light scattering. In this work it was found that particles with best activity and stability were obtained by encapsulator. For manual particles the best results were found in the liposome particles. Liposomes exhibited the smallest particle size, the highest efficiency encapsulation, excellent stability in real food and juices and the best value of zeta potential.
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2

Osecká, Karolína. "Možnosti ovlivnění vstřebávání kofeinu z kolových nápojů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2014. http://www.nusl.cz/ntk/nusl-217018.

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This diploma thesis was focused on basic physicochemical properties of caffeine and investigation of the interaction between the polysaccharide sodium hyaluronan (HA), pectin (PEC) or lignohumate (HUM) and the alkaloid caffeine (CAF). The reason why this thesis was focused on study of aqueous solutions of hyaluronan or pectin with caffeine is that the presence of polysaccharide- caffeine complex could be beneficial for slowing the absorption of caffeine. In the theoretical part of the diploma thesis there is described a group of alkaloids, which caffeine belongs to and also polysaccharides hyaluronic acid and pectin. The most attention has been paid to caffeine, its properties and effects on the human organism. This diploma thesis also deals with non-alcoholic beverages with caffeine, 4-methylimidazole, and phosphoric acid. The last chapter of the theoretical part is dedicated to fluorescence spectroscopy. In the experimental part of this work I deal with the basic properties of caffeine and interaction between the caffeine and selected polysaccharides or lignohumate. At first, the chemical and physical properties of caffeine were determined. Based on these results the interaction of caffeine and hyaluronan or pectin was studied by using the fluorescence and absorbance. The HA of molecular weight of 1,7 MDa and pectin from citrus fruits were chosen for the study of the interaction with the caffeine. These two substances were mixed with the caffeine of concentration contained in Coca-Cola. The results of interaction that would lead to the influence of the emission or absorption properties of caffeine, were not proved. As a part of the work there was determined how pectin behaves in strongly acidic solution and then there was monitored the pH, conductivity and solubility of caffeine in water by using thermogravimetry and visual experiments. The obtained results of the interaction of hyaluronan-caffeine, pectin caffeine or caffeine-lignohumate can be used for description of the behavior of caffeine in the presence of selected polysaccharides and natural organic substance.
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3

Minja, Bogunović. "Uklanjanje benzofenona i kofeina procesima prečišćavanja voda." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=110884&source=NDLTD&language=en.

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Benzofenoni  i  kofein  su  sveprisutni,  kako  u  otpadnim,  tako  i  upovršinskim vodama, u koncentracijama od nekoliko ng/l do mg/l. Koriste seu proizvodnji kozmetičkih preparata, kao  pojačivači mirisa i ukusa, fiksatoriu  parfemima,  aditivi  u  plastici,  sredstvima  za  čišćenje,  u  proizvodnjipesticida.  Benzofenoni  su  UV  filteri  pa  se  često  koriste  u  proizvodnjisunčanih  naočara,  kao  i  u  proizvodnji  sapuna  i  parfema,  sprečavajući  UVzrake  da  oštete  miris  ili  boju  proizvoda.  BP-3  se  najčešće  koristi  ukozmetičkoj  industriji  kao  UV  filter  u  kremama  za  sunčanje,  losionima  zatelo,  šamponima,  bojama  i  sprejevima  za  kosu.  Kofein  se  primenjuje  uproizvodnji  prehrambenih  proizvoda,  lekova  i  kozmetičkih  preparata.Značajno  se  razlikuju  po  hidrofilnosti  (benzofenon  log  Kow  3,18;benzofenon-3  log  Kow  3,79;  kofein  log  Kow  -0,07).  Usled  nedostatkapodataka o sadržaju odabranih predstavnika benzofenona (benzofenon (BP) ibenzofenon-3(BP-3)) i kofeina (CF)  u različitim tipovima vode  (pre svega ulokalnim  otpadnim  vodama  i  rečnoj  vodi)  i  njihovom  ponašanju  utretmanima  voda,  izvršena  su  ispitivanja  u  efluentu  tipičnog  postrojenja  zapreradu  otpadnih  voda  i  rečnoj  vodi  Dunava.  Utvrđeno  je  da  su  sve  trikomponente  prisutne  u  efluentu  WWTP  (BP  od  0,112  µg/l  do  0,146  µg/l;BP-3 od 0,00718 µg/l do 0,42 µg/l; CF od 0,2 µg/l do 12 µg/l) i u Dunavu(maksimalno detektovana koncentracija je za BP 0,95 µg/l, za BP-3 0,62 µg/li  za  CF  0,7  µg/l).  Pored  ispitivanja  sadržaja  ovih  jedinjenja  ispitana  jeefikasnost nekonvencionalnih procesa u obradi efluenta WWTP  (adsorpcija,koagulacije,  PAC/CoA,  PAC/UF)  i  konvencionalnih  (adsorpcija,koagulacija)  i  nekonvencionalnih procesa (PAC/CoA, PAC/UF, CoA/UF)  uobradi  rečne  vode.  Pored  toga  ispitani  su  efekti  prirodnih  procesaprečišćavanja u rečnoj vodi.Nekonvencionalni  procesi  za  prečišćavanje  otpadnih  voda  su  ispitani  pripočetnoj  koncentraciji  supstanci  od  0,96  µg/l  do  2  µg/l.  Adsorpcija  naaktivnom  uglju  u  prahu  se  pokazala  efikasnom  (benzofenoni  se  uklanjaju>84%  -  >94% u zavisnosti od doze uglja, a kofein je moguće ukloniti i do84%).  Koagulacija  dozama  prirodnog  koagulanta  od  0,0375  ml/l  ikomercijalnog koagulanta  FeCl3 od 4 mg Fe 3+ /l se  pokazala  neefikasnom zasve  supstance  (<20%).  Hibridni  PAC/CoA  koji  je  ispitivan  sa  različitimdozama  aktivnog  uglja  u  prahu  (5  i  20  mg/l),  prirodnim  koagulantom(0,0375 ml/l)  ili  komercijalnim  koagulantom  (4 mg Fe 3+ /l),  pokazao  se  kaoefikasan za uklanjanje BP, BP-3 i CF sa većom dozom  uglja A od 20 mg/l (>88%).  Hibridni membranski proces  PAC/UF je pokazao  visoku efikasnost za uklanjanje BP-3 (>68%) i CF (>99,95%) sa dozom uglja od 20 mg/l. Ispitivanjem  biodegradacije  BP,  BP-3  i  CF  primenom  laboratorijskog  test filtra, postignuta je efikasnost uklanjanja pri koncentraciji od 20 µg/l od  90% do  99%  i  pokazano  da  su  supstance  biodegradabilne.  Testovi  toksičnosti pokazali  su  značajno  smanjenje  ukupne  toksičnosti  smeša  tokom laboratorijskog  testa,  a  rezidualna  toksičnost  u  odnosu  na  D.  magna  može biti  posledica  nedetektovanih  transformacionih  produkata.  Transportom supstanci kroz sediment Dunava  uočeno je da  sediment predstavlja efikasnu barijeru  za  oba  testirana  benzofenona,  dok  CF  lako  prolazi  usled  svoje mobilnosti (log Kow -0,07). Eksperimentima fotodegradacije potvrđeno je da degradacija benzofenona UV zračanjem  zavisi od prisustva  anjona (HCO3 -, Cl i SO4 2-)  i DOC  u vodenom matriksu. Iako primenjeno UV zračenje nije bilo  realno  za  dezinfekciju  u  tretmanima  voda,  rezultati  su  pokazali značaj detaljnije  procene  kvaliteta  vode  u  slučajevima  kada  se  UV  zračenje primenjuje.Za uklanjanje odabranih supstanci iz rečne vode ispitani su  konvencionalni procesi  (zasebno  adsorpcija  na  aktivnom  uglju  u  prahu  i  koagulacija komercijalnim  koagulantom,  BOPAC ® )  i  hibridni  ili  nekonvencionalniprocesi  adsorpcije/koagulacije  (PAC/CoA),  adsorpcije/ultrafiltracije (PAC/UF) kao i koagulacije/ultrafiltracije (CoA/UF). Tokom ispitivanja PAC/CoA sa ugljem B (2 mg/l) i BOPAC ® (2 mg Al 3+ /l) u određenim  procesnim  kombinacijama,  (tokom  sukcesivnog  dodavanja  prvo uglja  B,  a  zatim  koagulanta)  uočene  su  specifičnosti  za  BP,  efikasnost uklanjanja BP je iznosila 92%. U slučaju doziranja prvo koagulanta, a zatim uglja  B  i  tokom  simultanog  doziranja  koagulanta  i  uglja  B,  efikasnosti  su iznosile  23  i  20%,  redom.  To  je  verovatno  posledica  kompeticije  iliblokiranja pora  uglja  POM iz rečne vode.  BP-3 se efikasno uklanjao tokom svih procesnih kombinacija sa ugljem B (87-93%), dok je za CF efikasnostuklanjanja iznosila  od 0-12%.  Hibridni procesi su se pokazali efikasniji priprimeni uglja C. U slučaju BP efikasnost je iznosila 81-90% i za CF 17-27% ,dok  je  za  BP-3  efikasnost  iznosila  od  71%  do  96%.  Hibridni  membranski procesi  PAC/UF  i  CoA/UF  u  obradi  rečne  vode  efikasni  su  u  uklanjanju supstanci  sa  visokim  log  Kow.  Benzofenoni  su  u  hibridnim  membranskim procesima  uklonjeni  od  69%-96% iz rečne  vode, dok su za kofein utvrđeni promenljivi rezultati i potreba za daljim istraživanjima.
Benzophenones and caffeine are ubiquitous  in wastewaters  and in surface  waters,  in  concentrations  that  vary  from  ng/L  to  mg/L. Benzophenones  are  used  as:  smell  and  flavor  enhancers,  perfume  fixers, plastic additives, cleaning agents, as well as in the pesticide manufacturing processes.  Their  UV-resistant  properties,  makes  benzophenones  a  suitable packaging component  –  to  prevent UV light from damaging the odor or the color of the product. Similarly, benzophenone-3 is most commonly used in the  cosmetics  industry;  as  a  UV  filter  agent  in  sunscreens,  body  lotions, shampoos, paints and hair sprays.  On the other hand, caffeine is prevalent in food-,  pharmaceutical-  and  cosmetics-manufacturing.  However, benzophenones  and  caffeine  have  significantly  different  log  Kow  values. Log Kow values for benzophenone and benzophenone-3 are 3.18 and 3.79,respectively, while for caffeine log Kow is  -0.07.  Due to the lack of data on the  content  of  selected  benzophenones,  (benzophenone  (BP)  and benzophenone-3  (BP-3))  and  caffeine  (CF)  in  different  types  of  water (primarily in local wastewater and  river water) and their behavior in water treatments, tests were  carried out: a) in the effluent of a typical wastewater treatment  plant (WWTP);  b) and  in  the river Danube.  In case of the WWTP effluent, the presence of all three compounds was detected in the following ranges: 0.112 μg/L to 0.146 μg/L for BP, 0.00718 μg/L to 0.42 μg/L for BP-3,  and  0.2  μg/L  to  12  μg/L  for  CF.  With  respect  to  the  Danube  river,  the highest  detected  concentration  for  BP  was  0.95 μg/L,  for  BP-3  was 0.62 μg/L,  while  CF  in  Danube  river  sample  was  measured  in  only  one sample, resulting in a concentration of 0.7 μg/L. In addition, this  work has investigated  the  efficacy  of  several  treatment  processes:  unconventional processes  in  the  WWTP  effluent  treatment  (adsorption,  coagulation, PAC/CoA, PAC/UF);  as well as the  conventional (adsorption, coagulation) and  unconventional  processes  (PAC/CoA,  PAC/UF,  CoA/UF)  in  the treatment  of  river  waters.  Furthermore,  the  effects  of  natural  purification processes  in  river  water  had  also  been  examined  within  the  scope  of  this research.Unconventional  wastewater  treatment  processes  were  investigated  at  initial concentrations  of  selected substances  that ranged  from 0.96 μg/L to 2 μg/L. Adsorption  on  powder  activated  carbon  was  effective  for  removal  of benzophenones  (> 84%  -> 94%)  and caffeine  (84%),  depending on the  dose of PAC A. Coagulation with doses of  natural coagulant of 0.0375 mL/L  and commercial  coagulant  FeCl 3 of  4  mg  Fe 3+ /L  was  ineffective  for  all substances  (<20%).  Hybrid  PAC/CoA  process,  investigated  with  different doses  of  PAC  A  (5  and  20  mg/L),  natural  coagulant  (0.0375  mL/L)  or commercial coagulant (4 mg Fe 3+ /L), proved to be effective for  the removal of BP, BP-3 and CF at a higher PAC A dose of 20 mg/L (> 88%). The hybrid membrane process PAC/UF proved to be highly effective in the  removal of BP-3 (> 68%) and CF (> 99.95%) with  20 mg/L  of  PAC A.  Biodegradation of BP, BP-3 and CF had been confirmed in Danube river water sample using a  laboratory  test  filter  filled  with  inert  material.  The  removal  efficacy  was 90-99%  at  a  concentration  of  20  μg/L.  Toxicity  tests  showed  significant reduction in total toxicity of the mixture during the  course of the  laboratory test,  whereas  the  residual  toxicity  in  relation  to  D.  magna  may  be  due  to undetected transformation products. Transportation of the substances through the  Danube  sediment,  indicated that sediment  acts as  an  effective barrier for both tested benzophenones, while  this is not  the  case with  CF.  Its mobility (log Kow  -0.07) allows CF to pass through the sediment.  Photodegradation experiments have confirmed that  BP  degradation  occurs due to  the presence of  anions  (HCO 3-, Cl  2-) and DOC in the aqueous matrix. Although the applied UV radiation was  not a realistic representation of disinfection in conventional water treatments, the results showed the importance of a more detailed  assessment  of  the  water  quality  in  cases  where  UV  radiation  is applied.  Herien  investigated  are  also  conventional  processes  (separately adsorption on PAC,  and coagulation  with commercial coagulant -  BOPAC ® ) and hybrid or unconventional  adsorption/coagulation  processes (PAC/CoA), adsorption/ultrafiltration (PAC/UF) and coagulation/ultrafiltration (CoA/UF) for the  removal of the selected substances from river water.The efficiency of BP  removal  via  PAC/CoA  with  PAC  B  (2  mg/L)  and  BOPAC ® (2 mg Al 3+ /L)  observed  specificity  of  removal  of  BP  in  certain  process combinations, such as successive addition of first PAC B and then coagulant. The efficacy of such BP removal was 92%. In case of the initial coagulant dosing, then PAC B, and in the case of simultaneous dosage of coagulant anPAC  B,  efficacy  were:  23%  and  20%,  respectively.  Such  outcome  is probably  a  result  of  the  competition/blocking  of  natural  organic  matter  in river  water.  BP-3  was  efficiently  removed  during  all  process  combinations with  PAC  B  (87-93%),  while  the  efficiency  of  CF  ranged  from  0-12%.  In general, hybrid process proved to be more efficient in case of PAC C. For BP and  CF,  the  efficacy  of  removal  amounted  to  81-90%  and  17-27%, respectively, wheareas the efficiency of BP-3 removal was found to be in the range  of  71-96%.  For  the  treatment  of  river  water,  hybrid  membrane processes PAC/UF and  CoA/UF are effective in the removal of  substances with  high  log  Kow.  Benzophenones  were  removed  from  hybrid  membrane processes  by  69%-96% from river water, while caffeine was found to have less consistent results and requires further research.
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4

Vránová, Petra. "Vývoj metody pro stanovení kvalitativních ukazatelů kakaového prášku." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-401855.

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The theoretical part of the master’s thesis is focused on a brief botanical characterization of the cacao tree and its most famous varieties discussed. Furthermore, the chemical composition of cocoa beans is described with an emphasis on theobromine and caffeine. There is also mention of the cocoa beans the cocoa bean processing technology for cocoa liquor and cocoa powder, which are then used in food industry. Additionally there is a shorta short description of the legal requirements relating to cocoa. In this part are also two chapters are devoted to the description of instrumentation of high performance liquid chromatography (HPLC) and inductively coupled plasma optical emission spectrometry (ICP-OES). The experimental part deals with analyzes of cocoa powder, cocoa beans, cocoa liquor and waste cocoa beans sold as a "tea mixture". A total of 10 legislation-recommended parameters have been identified in the listed raw materials, such as caffeine, theobromine and sucrose, heavy metal and potassium, fat content etc. The highest content of theobromine was determined in cocoa powder 178.363 mgl-1, caffeine in cocoa beans 16.096 mgl-1. All samples analyzed contained a little amount of sucrose as expected, the highest concentration was found in the tea mixture samples in both the water: ethanol sample of 84.069 mgl-1, and the sample solution in water of 65.897 mgl-1.
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Vysoká, Marie. "Vývoj energetických nápojů nového typu s obsahem přírodních aktivních složek." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-316171.

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The aim of this thesis is the development and preparation of a new energy drink. The theoretical part of the thesis focuses on the comparison of the drinks available in market, the presentation of the main active ingredients and the proposal of enriching the new energy drink. It also describes the possibility of using an encapsulation and the method used to determine specific compound in energy drink or encapsulated particles. In the experimental part of the work, at the beginning, the main content of energy drinks were characterized, for instance caffeine, sugar, polyphenol and vitamin C. Subsequently the energy drink based on selected types of loose teas that were enriched with the encapsulated extract of acai, acerola, maca, goji and ginseng was designed. All extracts contained large amounts of polyphenols and antioxidants. In addition, acerola extracts contained very high amounts of vitamin C. Two types of particles, alginate particles and liposomes were prepared for encapsulation. For all particles, encapsulation efficiency, size, stability, and antioxidant activity were determined. Long-term stability was then monitored within three months. The particles were also exposed to artificial gastric, pancreatic and bile juice. All tested particles showed very good encapsulation efficiency. In terms of long-term storage stability in an aqueous environment. Particularly liposome particles, which also showed high stability by zeta potential measurement, were suitable. On the contrary, in case of alginate particles, when stored in an aqueous medium, the release of active substances occurred. Finally, an energy drink was created and subjected to sensory analysis. The best energy drink was based on black or green tea with alginate particles acai, goji and ginseng.
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Hadlowska, Eliza. "Koffein mot huvudvärk : Effekten av koffein mot spänningshuvudvärk och migrän." Thesis, Umeå universitet, Institutionen för integrativ medicinsk biologi (IMB), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-179338.

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Vejrostová, Petra. "Studium směsných přírodních antimikrobiálních preparátů a možnosti jejich stabilizace." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2016. http://www.nusl.cz/ntk/nusl-240734.

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Present diploma thesis is focused on natural antimicrobial substances. The aim of the experimental part of thesis was testing of antimicrobial activity of selected natural substances in free and encapsulated forms, preparation of particles and monitoring of their long-term stability. Various teas extracts (aqueous, ethanoic and DMSO) and aqueous herbs extracts were used as plant antimicrobial substances. Liposomes and chitosan particles with encapsulated aqueous teas extracts were prepared by ultrasonication. Encapsulation efficiency, size, stability and antioxidant activity for all particles were specified. Consequently, within a two months period, long-term stability for these particles was monitored. Spectrophotometric method for determining total polyphenols was used for evaluating encapsulation efficiency as well as for monitoring of long-term stability. The DLS method was used for determination of size and stability of particles. Antioxidation activity was monitored by using spectrophotometric method using ABTS. For testing antimicrobial activity of various types of teas, herbs extracts and their mixtures and combianitons with lysozyme and antibiotics, broth dilution methods were used while using both Gram positive and Gram negative bacterial test strains. Antimicrobial activity of prepared particles was also monitored, the antimicrobial activity was especially significant with the chitosan particles. Suitable combinations of natural substances whatever with antimicrobial or antioxidation effect either in free or encapsulated form could be used for applications for example in cosmetics industry, food processing or in medicine.
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Dušica, Popović. "Delovanje lekova registrovanih za neonkološke indikacije na eksperimentalni fibrosarkom hrčka." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=110281&source=NDLTD&language=en.

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Mnogi lekovi registrovani za razne druge indikacije mogu da deluju selektivno na tumorske receptore, signalne puteve, metaboličke procese, bioenergetske faktore, enzime, proteine, gene koji regulišu proliferaciju, apoptozu i neoangiogenezu tumora ne pogađajući ove procese kod zdravih ćelija. Uvođenje novih lekova je izrazito dug, složen i skup proces istraživanja. Korišćenjem principa otkrivanja antikancerskog efekta kod već registrovanih lekova za druge indikacije, direktno se utiče na skraćivanje vremena i troškova istraživanja. Eksperimentalno je ispitana efikasnost antitumorskog delovanja mebendazola, metformina, itrakonazola, diklofenaka, nitroglicerina i deoksiholne kiseline na fibrosarkom hrčka izazvan BHK21/C13 tumorskom ćelijskom linijom praćenjem veličine i histologije lečenih tumora. Eksperimentalno je ispitana mogućnost primene deoksiholne kiseline, nitroglicerina, kofeina i itrakonazola kao adjuvansa u kombinaciji sa pojedinim ispitivanim lekovima (metformin, itrakonazol, diklofenak) za lečenje fibrosarkoma hrčka. Kako je ispitivanje vršeno na mladuncima imladim hrčkovima i kako su sarkomi najčešći u dečijem uzrastu, definisanje potencijalne antikancerske uloge ispitivanih lekova se odnosi prvenstveno na njihovu primenu u pedijatriji. Pokazano je da metformin, kombinacije metformina sa kofeinom, metformina sa itrakonazolom i metformina sa nitroglicerinom deluju u pogledu svih ispitivanih parametara tumora antitumorski na fibrosarkom hrčka. Kofein, itrakonazol i nitroglicerin pojačavaju antitumorsko dejstvo metformina na fibrosarkom hrčka. Tokom svih eksperimenata realizovanih u okviru ove disertacije, pokazalo se da nije bilo delotvornog tretmana, koji ne sadrži metformin.
Many drugs registered for various other indications can act selectively to tumor receptors, signaling pathways, metabolic processes, bioenergetic factors, enzymes, proteins, genes that regulate proliferation, apoptosis, and neoangiogenesis of the tumor without affecting these processes in the healthy cells. The introduction of new drugs is a very long, complex and expensive process of research. Using the principle of detecting the anticancer effect in already registered drugs for other indications, directly affects the reduction of time and cost of research. The efficacy of mebendazole, metformin, itraconazole, diclofenac, nitroglycerin and deoxycholic acid antitumor activity on hamster fibrosarcinoma induced experimentally by the BHK21/C13 tumor cell line was tested by monitoring the size and histology of the treated tumors. The possibility of using deoxycholic acid, nitroglycerin, caffeine and itraconazole as an adjuvant in combination with investigated drugs (metformin, itraconazole, diclofenac) for the treatment of hamster fibrosarcoma has been experimentally tested. As the examination was carried out on young cubs and young hamsters and that sarcomas are the most common in childhood, defining the potential anti-cancer role of the investigated drugs relates primarily to their application in pediatrics. Metformin, combinations of metformin with caffeine, metformin with itraconazole and metformin with nitroglycerin have shown antitumor action on the hamster fibrosarcoma in terms of all tested tumor parameters. Caffeine, itraconazole and nitroglycerin increase the antitumor effect of metformin on the hamster fibrosarcoma. During all the experiments carried out within this dissertation, there has been no effective treatment, which does not contain metformin.
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Karlsson, Johannes, and Sara Weiberth. "Koffeinets ergogena effekter på power i överkropp." Thesis, Högskolan Dalarna, Idrotts- och hälsovetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:du-22619.

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Koffein har sedan 1962 fram och tillbaka varit dopingklassat men är sedan 2004 ett tillåtet ergogent preparat inom idrotten. Flera studier har visat positiva resultat i uthållighetsidrotter och på maximal styrkeförmåga. Syftet med denna studie var att se om koffein har någon ergogen effekt på power i överkroppsmuskulaturen. I denna studie användes en dubbel-blindad, randomiserad cross-over design. En slumpmässig indelning inför det första testtillfället avgjorde ifall deltagarna började studien med koffein- eller placebosupplementering och bytte sedan supplementering inför testtillfälle två. Som supplementeringsmetod användes koffein i tuggummiform på grund av att det ger ett snabbare upptag. Power mättes genom testet sittande stöt med en kula på 5 kg. Resultatet visar på en mycket svag (ES=0,13) positiv förbättring av stötlängderna mellan interventionerna. En av anledningarna till det triviala resultatet tros kunna bero på att det urval som användes ej bestod av en homogengrupp vad gäller träningsbakgrund och prestationsnivå. På grund av detta är det svårt att dra några slutsatser om koffeinet har eller inte har några ergogena effekter på power i överkroppen.
Since 1962 Caffeine has been off and on the doping classification list, since 2004, it has been permitted as an ergogenic agent in sport. Several studies have shown positive ergogenic effects in endurance sports and in maximum strength capacity. The purpose of this study was to determine if caffeine has any ergogenic effect on power in the upper body. In this study, a double-blind, randomized cross-over design was used. Participants were randomly selected to start the intervention with either caffeine or placebo supplementation and then have the alternative supplementation before a second test, held after a 48 hour washout period. A supplementation method Caffeinated chewing gum was used as a supplementation method due to its faster uptake by the body. The distance that a 5 kg shot put could be launched from a sitting position was used as a measure of upper body power. The results showed a 1,7 % but trivial (ES = 0.13) difference in shot put lengths between the interventions, in favour of the caffeine 3 intervention. One of the reasons for the lack of a clear ergogenic effect is believed to be due to the non-homogenous group, in terms of training background, level of performance and the resulting low level of within-participant reliability. Because of this it is difficult to draw any conclusions regarding caffeine and its ergogenic effects on power in the upper body.
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10

Nilsson, Mikaela Nilsson. "Koffeins påverkan på tårproduktionen." Thesis, Linnéuniversitetet, Institutionen för medicin och optometri (MEO), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-35491.

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Syfte: Syftet med arbetet var att undersöka om ett intag av koffein kan påverka tårproduktionen med hjälp av Schirmer 1 test. Metod: I det här arbetet deltog 30 personer i åldrarna18 – 28 år (medelåldern var 22,3 ± 2,1 år) som var uppdelade i två grupper med 15 personer i varje grupp. Den ena gruppen fick 200 ml vatten och 300 mg koffein och den andra fick bara 200 ml vatten. Alla deltagares tårproduktion mättes fyra gånger, en gång före intag, efter intag mättes tårproduktionen efter både 30, 60 och 90 minuter. Tårproduktionen mättes med hjälp av Schirmer 1 test, vilket är en pappersfilters remsa med en graderad mm-skala som hängs fast i deltagarens undre ögonlock, där den absorberar ögats tårar. Resultat: Det fanns ingen statistisk signifikant skillnad (p > 0,05) efter koffeinintag, men det fanns det efter vattenintag på höger öga där tårproduktionen minskning var statistiskt signifikant mellan första och sista mätningen (p = 0,011). Slutsats: Det fanns ingen statistisk signifikant skillnad (p > 0,05) efter koffeinintag. Vilket innebär att en normal dos med koffein inte kan ge upphov till torra ögon.
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11

Fridh, Mikael, and Simon Krüger. "Kaffe och energidryck : Den sociala utvecklingen och konsumtionen av koffein." Thesis, Örebro universitet, Restaurang- och hotellhögskolan, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-33319.

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Kaffet började ursprungligen konsumeras för koffeinets effekter, vidare utvecklades kaffet och blev en social dryck. Kaffe spreds runt hela världen och koffeinet användes som tillsatts i energidryck och andra livsmedel. Syftet är att undersöka utvecklingen av koffeinets konsumtionsmönster och sociala roll i kaffe och energidryck. Arbetet är en litteraturstudie baserad på fyra vetenskapliga artiklar som samlats in genom två olika databaser. Urvalet av artiklar skedde med hjälp av förbestämda kriterier. Resultatet visar att koffein i dryck ger njutningsfyllda effekter men även bieffekter finns. Koffeinet har utvecklats som tillsatts i bland annat energidryck samt läsk och konsumtion av energidryck kopplas till problembeteenden. Detta livsmedel konsumeras ibland med alkohol och det finns konsekvenser med denna konsumtion. Kaffet har utvecklats till en social dryck och det går koppla denna dryck samt te till olika livsstilar. I diskussionen påvisas det att kaffe och te har en stors ocial roll i samhället. Energidryck och läskedryck visar sig inte ha någon förankring som en social dryck. Vidare talas det om konsumtionen av kaffe, energidryck, te och läskedryck. Konsumtionen av koffeinhaltiga drycker ökar men huruvida kaffet kommer ha en central roll  bland de sociala dryckerna i framtiden är osäkert.
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12

Angelin, Mathias, and Anton Hallor. "Kan koffein innan träning förbättra den aeroba prestationen över tid?" Thesis, Örebro universitet, Institutionen för hälsovetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-59405.

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Introduktion : För att prestera väl inom en uthållighetsbaserad idrott krävs en hög aerob förmåga. För att öka den aeroba prestationen krävs träning, vilket har varit känt länge. Att maximera effekten av träningen är av stort intresse hos de allra flesta idrottare. Forskare studerar hela tiden nya tekniker för att försöka optimera ökningar i den aeroba prestationen. Koffein ökar akut tiden till utmattning vid given belastning, men frågan kvarstår om koffein även skulle kunna öka den aeroba prestationen över tid. Syfte : Att undersöka den långvariga effekten vid intag av 5mg/kg kroppsvikt koffein innan högintensiva intervallpass över tid på den aeroba prestationen hos motionslöpare. Metod: En randomiserad mellangrupps-studie med 5mg/kg kroppsvikt koffein och placebo. 16 deltagare (3 kvinnor och 13 män; medelvärde ± SD, 42 ± 8 år, VO2max: 47,6 ± 6,6 ml/kg/min) deltog i studien. Pre- och post-tester gjordes för VO2max och 3km löpning. Intervention bestod av två högintensiva löp-pass per vecka med intag av antingen koffein eller placebo 30–60 minuter innan träning. Borgskalan (6–20) användes som mått på ansträngning under intervaller. För att beräkna skillnader mellan grupper användes oparat t-test mellan grupper samt parat t-test inom grupp. Signifikansnivån sattes till P <0,05. Resultat : Ingen signifikant skillnad i delta(Δ) uppmättes mellan Δkoffein och Δplacebo i någon av mätningarna. Signifikant förbättring i tid på 3km löpning (P <0,05) för båda grupper, signifikant förbättring i VO2max för placebogrupp. Slutsats : Intag av 5mg/kg kroppsvikt koffein 30–60 minuter innan 2 högintensiva intervallpass/vecka har ej ytterligare effekt på den aeroba prestationen jämfört med placebo över en sex veckor lång intervention.
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13

Seidel, Bettina [Verfasser]. "Der Einfluss von Koffein auf False Memories nach Schlafdeprivation / Bettina Seidel." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2011. http://d-nb.info/1017188572/34.

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14

Johansson, Gisela. "Effekten av koffein på fysiologiska variabler vid upprepade Wingatetester vid armcykling." Thesis, Mittuniversitetet, Avdelningen för hälsovetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-25333.

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15

Dziallas, Peter [Verfasser]. "Prüfung der immunmodulatorischen Wirkung von Coffea praeparata und Koffein / Peter Dziallas." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2015. http://d-nb.info/1073847608/34.

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16

Nezirevic, Ersed. "Koffein och muskulär uthållighet : En studie om koffeinets roll för prestationsförmågan." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-65813.

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Koffein är en populär substans som konsumeras i stora mängder världen över och dess prestationshöjande effekt har studerats i många studier genom åren. Framför allt ses en effekt vid uthållighetstest på 30-60 min vid intag av 3-6 mg/kg koffein. I denna studie med 10 måttligt tränade individer med oregelbundna konsumtionsvanor av koffein var syftet att undersöka om muskulär uthållighet kan öka efter koffeinkonsumtion. Studien bestod av ett cykeltest och ett efterföljande benpresstest på 65 % av maximal ansträngning där varje individ genomförde ett placebotest och ett koffeintest. Studiens dos av 200 mg koffein motsvarade för samtliga testpersoner en låg dos som understeg 3 mg/kg kroppsvikt. Konsumtion av koffein resulterade i en signifikant minskning av pulsen efter koffeinkonsumtion med ett p-värde på 0,045. Vid koffeinintag var medelpulsen 77,9 ± 6,6 och 82,2 ± 7,2 vid intag av placebo där det i genomsnitt var en pulsminskning på 5,2 % och 4,3 slag mindre/minut av koffein. Den upplevda ansträngningen skattades också lägre vid intag av koffein men skillnaden mellan koffein och placebo var inte signifikant (p=0,18). Den upplevda ansträngningen skattades till 14,4 ± 1,9 med koffein och 16 ± 2,5 med placebo. I benpresstestet genomförde koffeingruppen 1,9 repetitioner fler än i placebogruppen med ett medelvärde på 21,5 ± 6,5 och 19,6 ± 6,4. Skillnaden mellan koffein och placebo var dock inte signifikant med ett p-värde på 0,317. Studien visar att koffein i låga doser kan påverka ansträngningsgraden men en signifikant ökning av den muskulära uthålligheten med ett benpresstest uteblev.
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17

Aoki, Takashi. "Kofun chikuzō no kenkyū funkyū kara mita kofun no chiikisei /." Tōkyō : Rokuichi Shobō, 2003. http://books.google.com/books?id=pk9YAAAAMAAJ.

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18

Vesna, Zeljković. "Дејство метформина и нитроглицерина са 2-деокси-Д-глукозом и кофеином на одабраним ћелијским културама." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=110867&source=NDLTD&language=en.

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У овој дисертацији испитивана су антитуморска дејства антихипергликемијског лека метформина, вазодилататорног лека нитроглицерина, и комбинација ових лекова са дијагностичким средством 2-деокси-D-глукозом и/или радио и хемио сензибилизатором кофеином на хуманим културама аденокарцинома плућа (A549), колоректалног карцинома (HT29), аденокарцинома цервикса (HeLa), као и на контролној ћелијској култури нормалних фибробласта плућа (МRC 5). In vitro испитивање утицаја метформина, нитроглицерина, 2-деокси-D-глукозе и кофеина на проли- ферацију ћелија карцинома грлића материце (HeLa), ћелијској култури аденокарциномa плућа (A549) и ћелијској линији карцинома дебелог црева (HT29). Ћелије у експоненцијалној фази раста третиране су растућим концентрацијама метформина, нитроглицерина и 2-деокси-D-глукозе и утврдила се дозна зависност цитотоксичног ефекта. Метформин, кофеин и 2-деокси-D-глукоза су утицали на смањење процента преживљавања туморских ћелија, док је применом нитроглицерина овај ефекат изостао, иако у експериментима код истовремене примене нитроглицерина и кофеина постоји пад процента преживелих ћелија. Најпотентнији ефекат је постигнут код истовремене примене метформина и кофеина, док је разлог за одсуство снажног цитотоксичног ефекта метформина и 2-деокси-D-глукозе код комбиноване примене молекуларни механизам деловања појединачних супстанци. Снажан пролиферативни ефекат је евидентиран применом метформина и кофена на здравим фибробластима плућа.
U ovoj disertaciji ispitivana su antitumorska dejstva antihiperglikemijskog leka metformina, vazodilatatornog leka nitroglicerina, i kombinacija ovih lekova sa dijagnostičkim sredstvom 2-deoksi-D-glukozom i/ili radio i hemio senzibilizatorom kofeinom na humanim kulturama adenokarcinoma pluća (A549), kolorektalnog karcinoma (HT29), adenokarcinoma cerviksa (HeLa), kao i na kontrolnoj ćelijskoj kulturi normalnih fibroblasta pluća (MRC 5). In vitro ispitivanje uticaja metformina, nitroglicerina, 2-deoksi-D-glukoze i kofeina na proli- feraciju ćelija karcinoma grlića materice (HeLa), ćelijskoj kulturi adenokarcinoma pluća (A549) i ćelijskoj liniji karcinoma debelog creva (HT29). Ćelije u eksponencijalnoj fazi rasta tretirane su rastućim koncentracijama metformina, nitroglicerina i 2-deoksi-D-glukoze i utvrdila se dozna zavisnost citotoksičnog efekta. Metformin, kofein i 2-deoksi-D-glukoza su uticali na smanjenje procenta preživljavanja tumorskih ćelija, dok je primenom nitroglicerina ovaj efekat izostao, iako u eksperimentima kod istovremene primene nitroglicerina i kofeina postoji pad procenta preživelih ćelija. Najpotentniji efekat je postignut kod istovremene primene metformina i kofeina, dok je razlog za odsustvo snažnog citotoksičnog efekta metformina i 2-deoksi-D-glukoze kod kombinovane primene molekularni mehanizam delovanja pojedinačnih supstanci. Snažan proliferativni efekat je evidentiran primenom metformina i kofena na zdravim fibroblastima pluća.
In this dissertation, the anti-cancer effects of an antihyperglycaemic agent of metformin, a vasodilator drug nitroglycerin, and a combination of these drugs with a 2-deoxy-D-glucose diagnostic agent and / or radio and hemio sensitizer with caffeine on human cultures of adenocarcinoma of the lungs (A549), colorectal carcinoma (HT29), cervix adenocarcinoma (HeLa), as well as on the control cell culture of normal fibroblasts of the lungs (MRC 5). An in vitro study of the effects of metformin, nitroglycerin, 2-deoxy-D-glucose and caffeine on the proliferation of cervical cancer cells (HeLa), cell culture of the lung adenocarcinoma (A549), and colon cancer of the colon (HT29). The cells at the exponential growth stage were treated with rising concentrations of metformin, nitroglycerin and 2-deoxy-D-glucose, and the cytotoxic effect was determined. Metformin, caffeine, and 2-deoxy-D-glucose reduced the number of tumor cells, while nitroglycerin did not it could be concluded. Although there is a decrease in survival in experiments with the simultaneous administration of nitroglycerin and caffeine, the most effective effect is achieved in the simultaneous use of metformin and caffeine, while the reason for the absence of a potent cytotoxic effect of metformin and -deoxy-D-glucose is the molecular mechanism of the action of individual substances. The most significant effect was achieved with the simultaneous administration of metformin and caffeine to the cell culture of lung adenocarcinoma. A potent proliferative effect was recorded using metformin and 2-deoxy-Dglucose on healthy lung fibroblasts.
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Muombwa, Mohamed Ameir. "Kofia in Zanzibar." Universitätsbibliothek Leipzig, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-95265.

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There are many different traditional costumes in the world. In Zanzibar, a Swahili man is said to be fully attired when he puts on an embroidered cap, locally known as kofia ya viua or just kofia, robe (kanzu) with a coat, and sandals taking a Swahili name of makubadhi. The Kofia is round-shaped with a flat top, adorned with embroidered designs all over For convenience of simplicity in classification kofia are divided into two main groups, simple designed and complex-designed caps.
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Muombwa, Mohamed Ameir. "Kofia in Zanzibar." Swahili Forum; 2 (1995), S. 132-137, 1995. https://ul.qucosa.de/id/qucosa%3A11622.

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There are many different traditional costumes in the world. In Zanzibar, a Swahili man is said to be fully attired when he puts on an embroidered cap, locally known as kofia ya viua or just kofia, robe (kanzu) with a coat, and sandals taking a Swahili name of makubadhi. The Kofia is round-shaped with a flat top, adorned with embroidered designs all over For convenience of simplicity in classification kofia are divided into two main groups, simple designed and complex-designed caps.
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21

Klinthage, Jakob. "Koffeins påverkan på osmolariteten i tårfilmen." Thesis, Linnéuniversitetet, Institutionen för medicin och optometri (MEO), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-35953.

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Purpose: The purpose of this study was to investigate if there was a difference in the tear film’s osmolarity before and after drinking coffee. ' Method: All subjects in this study were asked to fill in a questionnaire to diagnose factors in their subjective symptoms, the questionnaire TERTC-DEQ. The subjects with a total graduated points of over 17 were not allowed to participate in the further measurements. In the study there was a total amount of 38 subjects, were 5 participated twice for both measurements, coffee and water. The measurements were done by TearLab to bring the the osmolarity values, of coffee and water, the before and after measurements, to be compared with each column. Each subject was measured before the drinks was served, 200 milliliters of water or 200 milliliters of coffee. 45 minutes after the first measurement, after the intake of one of the liquids, then the second measurement was occured with TearLab.  All of these values and measurements was later compared to each columns of coffee or water. Results: There was no significant difference between neither the coffee or water results (p>0,05). Though there was a little quotable difference between the before and after measurement values of coffee, but not significant. Conclusion: There was no significant difference related to coffe drinking and tear osmolarity. There is no contribution to the tear film’s osmolarity and it will not work as a factor into the dry eyes diagnosis.
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22

Hedman, Alexander. "Har kombinationen av koffein, beta-alanin, kreatin och L-arginin någon prestationshöjande effekt på styrketränande individer? : Med en randomiserad, dubbelblind samt placebokontrollerad studiedesign." Thesis, Linnéuniversitetet, Institutionen för idrottsvetenskap (ID), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-37777.

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Bakgrund: Idag finns det en stor marknad som enbart fokuserar sig på kostillskott, vars uppgift är att få styrketränande människor att prestera maximalt. Många sätter idag sin tro på de preparat som säljs i kostillskottsbutiker, detta medför att försäljningen av kosttillskott under de senaste åren har ökat explosionsartat runt om i världen, inte minst i Sverige. Syfte: Syftet med denna studie är att undersöka friska, fysiskt aktiva mäns styrka, muskulära uthållighet och deras mentala tillstånd vid konsumtion av prestationshöjande preparat (PWO) med ingredienserna koffein, beta-alanin, kreatin, och L-arginin. Metod: Denna studie använde en randomiserad, dubbelblind, placebokontrollerad studiedesign där 18 fullt friska, fysiskt aktiva män deltog. Testpersonerna utförde styrketester, uthållighetstester samt tester gällande deras mentala tillstånd vid intag av PWO och placebo (PL). Testresultaten analyserades sedan i SPSS.  Resultat: Bänkpressen samt uthållighetstestet påvisade ingen signifikant skillnad (p=0,362), (p=0,195). Styrketestet i knäböj visade däremot en signifikant skillnad mellan PWO och PL (Placebo) där deltagarana presterade bättre efter PWO (p=0,007). Den mentala energinivån visade ingen signifikant skillnad mellan PWO och PL (P=0,340). PWO visade dock på en signifikant förbättring av trötthetsnivå, (P=0,002), vakenhetsnivå (P=0,003) och fokuseringsnivå (P=0,002). Diskussion: Om nu PWO till förstone är anpassat och framför allt används av personer med en tydlig träningsinriktning i egenskap av att öka styrka. Prestationsökningen är något som är viktigt för inte bara personer som tränar utan även för dem som antigen rehab-tränar eller för dem som, av olika anledningar, ordineras träning av läkare. Frågan är om PWO kan användas på annat sätt än enbart för gymintresserade personer? Slutsats: PWO har en effekt att den möjliggör en förbättring av träningsresultaten på friska styrketränande individer 24 år ± 4 år
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23

Faxe, Borgryd Emma. "Har energidryck någon kognitiv effekt i kombination med alkohol? : Med fokus på komponeneten koffein." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-35381.

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Background: Energy drinks have been found in everyday-stores since 1997 and their popularity have increased over time. Consumtion of energy drinks takes place because of their ability to increase concentration and to decrease fatigue but also because of the popularity the drinks have got. Target groups for these stimulating beverages are adolescents and young adults. Energy drinks contain caffeine, taurine, glucuronolacton, carbohydrates and B-vitamins and voices have been raised about the eligibility for young people to ingest large quantities of these kinds of substances. Because of the properties of these substances it has become popular to mix energy drinks and alcoholic beverages to make up for the negative effects of alcohol and to be able to drink larger quantaties. Aim: The aim of this literature work was to investigate cognitive effects of the combination of caffeine in terms of energy drinks and alcohol and to determine if these effects could be harmful. Method: This literature work is based on five scientific articles retrieved from PubMed. Inclusion criteria for selection of the articles were examination of the effects of a combined use of alkohol and energy drinks. Results: A combination of energy drinks and alcohol can give a larger intake of alcohol and/or an overestimate of a persons abilities (for example to drive). Some effects can be seen in the perception of alcohol effects by simultaneous intake of alcohol and energy drinks because of the effect of caffeine. Discussion: There are many factors that can have an influence when it comes to effects of a combination of energy drinks and alcohol. Caffeine (in energy drinks) can have some impact on the perception of alcohol effects but also use of tobacco, contraceptives and energy states in the body can make a difference. Expectations that some substances could have an influence (placebo effect) might as well give an effect.
Bakgrund: Energidryck har funnits i dagligvaruhandeln sedan 1997 och populariteten har ökat kraftigt de senaste åren. Konsumtion av energidryck sker framförallt för att öka koncentrationsförmågan och motverka trötthet men också av popularitet. Målgruppen för dessa stimulerande drycker är i första hand ungdomar och unga vuxna. Energidryck innehåller koffein, taurin, glukuronolakton, kolhydrater samt B-vitaminer och röster har höjts huruvida det är lämpligt för unga att inta stora mängder av dessa substanser. P.g.a av produkternas egenskaper har det blivit populärt att blanda energidryck med alkoholhaltig dryck för att på så vis motverka alkoholens negativa effekter och kunna dricka mer. Syfte: Syftet med denna litteraturstudie var att undersöka vilka kognitiva effekter en kombination av koffein i form av energidryck och alkohol har och om dessa eventuella effekter kan vara skadliga. Metod: Undersökningen är en litteraturstudie baserad på vetenskapliga artiklar. Studierna i detta arbete hämtades från PubMed. Fem studier, varav fyra randomiserade kliniska prövningar och en enkätundersökning, valdes ut för granskning. Resultat: Energidryck i kombination med alkohol kan ge ett större alkoholintag och/eller en överskattning av sin förmåga (vid t.ex bilkörning). En viss effekt kan ses på upplevelsen av alkohol vid samtidigt intag av energidryck då koffein kan minska en del av alkoholens effekter. Diskussion: Många faktorer kan samverka i hur stor effekt en kombination av energidryck och alkohol har. Koffein (i form av energidryck) kan ha en viss inverkan på upplevelsen av alkohol men även tobaksbruk, preventivmedel och hur energitillståndet i kroppen är har betydelse. Förväntningar att en substans ska ha en effekt (placeboeffekten) kan också inverka.
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Livaniou, Rebecca. "Finns det ett samband mellan koffein och ångest hos unga vuxna? : En kvantitativ tvärsnittsstudie." Thesis, Gymnastik- och idrottshögskolan, GIH, Institutionen för fysisk aktivitet och hälsa, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-6650.

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Syfte och frågeställningar Syftet med studien är att undersöka sambandet mellan koffein och ångest hos 18-29 åringar. Den primära frågeställningen är om det finns ett samband mellan koffeinkonsumtion och ångest hos unga vuxna. Vidare även om det finns ett samband mellan koffeinkonsumtion och ångest i relation till kroppsvikt hos både män och kvinnor. I samband med detta är hypotesen att högre koffeinkonsumtion hänger ihop med högre ångestnivåer hos män och kvinnor. Metod Studien är en kvantitativ tvärsnittsstudie. En enkätundersökning utfördes online och 245 individer deltog. Av totalt 245 deltagare var 18% i åldrarna 18–21 år, 44,9% mellan 22–25 år och 37,1% mellan 26–29 år. Könsfördelningen var relativt jämnt fördelad då 42% var män och 58% var kvinnor. Studien hade inget bortfall. Enkätundersökningen bestod av tre kategorier; allmänna frågor, koffeinkonsumtionsfrågor samt ångestfrågor. De allmänna frågorna bestod av ålder, längd, vikt och kön. Koffein konsumtionsfrågorna baserades på en redan validerad enkät vid namn Diet and Behavior Scale (DABS) och som översattes till svenska (Richards et al., 2015). Ångestfrågorna baserades på en annan redan validerad enkät vid namn Generalized Anxiety Disorder – 7 questionnaire (GAD-7) (Sidik et al., 2012). Jag använde mig av en version som var översatt till svenska (Psykatristöd, u.å). Resultat Av totalt 245 deltagare hade 51 personer medel till hög grad av ångest. Dock hittades inget samband, samtidigt som resultatet var icke signifikant. Slutsats Eventuella orsaker till att studien inte visar ett samband kan vara att majoriteten av deltagarna skapat en koffeintolerans då många var regelbundna i sitt intag. Deltagarna kan även ha konsumerat en för låg dos för att kunna påvisa ångest. Då reaktionerna efter koffeinkonsumtion kan se olika ut från person till person är det svårt att generalisera för en hel grupp. Valet av studiedesign är inte heller det bästa med tanke på att en enskild personskoffeinkonsumtionsmönster och kroppsreaktion ser olika ut.För att få mer tydliga och specifika svar på sambandet mellan koffein och ångest skulle framtida forskning eventuellt behöva utföras experimentellt, då detta är ett ämne som är svårt att studera för en hel grupp.
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Oskarsson, Johanna. "Effekten av kombinerat koffein- och rödbetsjuiceintag på submaximalt och maximalt fysiskt arbete vid löpning." Thesis, Mittuniversitetet, Avdelningen för hälsovetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-27982.

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Matoušková, Petra. "Využití různých technik enkapsulace k řízenému uvolňování aktivních látek v potravinářských a kosmetických přípravcích." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2015. http://www.nusl.cz/ntk/nusl-234522.

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The presented doctoral thesis is focused on preparation, characterization and application of organic micro- and nanoparticles as transport systems for active components and some their complex natural sources. Active component were packed into liposomes and polysaccharide particles. As active components were used caffeine, some drugs – clotrimazole and ibuprofen, further antioxidants and vitamins. Antimicrobial herbs and spices extract, antimicrobial peptides lysozyme, nisin and other antimicrobial ingredients were encapsulated too. Encapsulation of selected hydrolytic enzymes was tested, too. Particles were also used for encapsulation of probiotic strains Bifidobacterium breve and Lactobacillus acidophilus and prebiotic components. These prebiotics were co-encapsulated into capsules with probiotic cells. Natural extracts were encapsulated e.g. extracts of guarana, ginseng, goji, green barley, propolis, black, green and white tea, coffee, fruit and vegetable extracts. The efficiency of encapsulation was determined by HPLC/PDA and by spectrophotometry. Long-term stability of particles and amount of released component in model/real foods, in model cosmetic conditions and in a model physiological environment were monitored too. Size of prepared liposomes and polysaccharide particles was determined by dynamic light scattering and by light microscopy and electron microscopy, respectively. Stability of the particles was measured using a zeta potential. Also, analytical centrifugation was used to measurement of sedimentation velocity and stability of the prepared particles. The antimicrobial activity were tested using two Gram-positive (Bacillus subtilis, Micrococcus luteus), two Gram-negative (Escherichia coli, Serratia marcescens) bacteria and one fungal strains (Candida glabrata). For determining the antimicrobial properties of active component and prepared particles two the most widely used methods were used - agar diffusion method and broth dilution method. The viability of probiotic strains were performed using flow cytometry and fluorescence microscopy. Encapsulation of active component was successful in all types of particles. Liposome showed a very good long-term stability mainly in water conditions with neutral pH and polysaccharide particles were stable in acidic conditions. Prepared particles showed a very good stability in model stomach environment, while in model intestines environments particles were disintegrated and active component were released. Prepared particles with encapsulated caffeine as well as other tested antioxidants and vitamins could be used to modern types of energy drinks, food supplements and also for some cosmetics applications. Encapsulated antimicrobial components could be used for food application as well as for cosmetics and pharmaceutical application like antimicrobial wound formulation. Encapsulated enzymes can be used for controlled release of proteases in wound healing, as delivery systems in digestive tract and as a part of pharmaceutical preparative and food supplements for enzyme therapy. The study revealed that encapsulation of probiotics and also co-encapsulation of probiotics with prebiotics exhibited longer stability of particles and survival bacterial cells. So, prepared particles are suitable for use to food product with beneficial effects on the human body.
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Hohlbein, Wolf [Verfasser], and Simon [Akademischer Betreuer] Rothenfußer. "Der Einfluss von Koffein auf die Interferonfreisetzung durch virale Stimuli / Wolf Hohlbein ; Betreuer: Simon Rothenfußer." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1200353730/34.

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Weichelt, Ulrike [Verfasser]. "Zur Wirkung des Xanthins Koffein auf den unreifen Organismus im Modell der neonatalen Ratte / Ulrike Weichelt." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2014. http://d-nb.info/1057869902/34.

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Kosmeas, Nikos. "Rasche und einfache Methode zur simultanen quantitativen Bestimmung von Paracetamol, Koffein, Phenobarbital und Propyphenazon in Plasma /." [S.l : s.n.], 1988. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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Didiodato, David Ray. "Nietzsche on "Life": An Examination of the Metaphors and their Significance." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20223.

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In this thesis Didiodato addresses a central theme in Nietzsche’s thought: namely, “life”. Nietzsche uses this term in a number of ways throughout his writings in many metaphorical, aphoristic, and often seemingly contradictory ways. This thesis attempts to flesh out what Nietzsche means by “life” by examining each of the particular ways Nietzsche uses the term in isolation. Ultimately, Didiodato argues that “life” is used in several fundamentally different ways which demonstrates Nietzsche’s criticism of metaphysical descriptions, while at the same time speaking to his emphasis on perspectivism. The thesis closes with a reflection on Nietzsche’s notion of the “affirmation of life” wherein this thesis argues that the diversity of accounts of life Nietzsche provides can find something of a unity.
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Gerdes, Anna [Verfasser], and Sebastian [Akademischer Betreuer] Hoffmann. "Einfluss von Koffein auf die laparoskopische manuelle Geschicklichkeit : eine prospektive randomisierte Doppelblindstudie / Anna Gerdes. Betreuer: Sebastian Hoffmann." Marburg : Philipps-Universität Marburg, 2015. http://d-nb.info/1068315156/34.

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Tonon, Matthias Emanuel [Verfasser], and Axel [Akademischer Betreuer] Steiger. "Die Wirkung von Ghrelin, Koffein, Methylphenidat und Modafinil als kognitive Enhancer / Matthias Emanuel Tonon ; Betreuer: Axel Steiger." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1190563525/34.

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Radžius, Linas. "Kofino kreivės parametrų ir mechaninių charakteristikų ryšio tyrimas būdingame intervale." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130821_151939-96251.

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Atlikta literatūros apžvalga parodė, kad tyrimų, nagrinėjant medžiagas būdingame intervale kambario ir aukštesnėje temperatūroje nebuvo atlikta. Todėl šiame darbe, nustatyti analizuojamų duomenų sklaidos intervalai: legiruotiems konstrukciniams plienams bei legiruotų konstrukcinių plienų suvirinimo siūlių medžiagoms (kambario ir aukštesnėje temperatūroje). Atliktas deformavimo, nuovargio parametrų ir modifikuoto plastiškumo kriterijaus reikšmių pasiskirstymo pagal normalųjį dėsnį hipotezių tikrinimas, kuris parodė, kad dauguma nuovargio nuo modifikuoto plastiškumo kriterijaus duomenų yra pasiskirstę pagal normalųjį dėsnį. Pasiūlyti analitinių priklausomybių koeficientai tarp suirimo kreivės parametrų ir modifikuoto plastiškumo kriterijaus. Gauti koreliacinės analizės duomenys patvirtino medžiagų atmetimo (būdingo intervalo nustatymo) tikslingumą. Tai reiškia, kad darbe nustatytos analitinės priklausomybės gali būti taikomos įrenginių konstrukcijų preliminariam ilgalaikiškumui bei patikimumui apskaičiuoti.
Performed literature review showed that any studies of examining materials in intrinsic range at room and elevated temperature haven’t been performed. That’s why, in this paper, analyzed data setted diffusion ranges-alloyed for structural steels and alloy structural steels weld (at room and elevated temperatures). Performed deformation, fatigue parameters and modified plasticity criteria value distribution by the normal law hypothesis testing, which showed that most of the fatigue plasticity criteria from modified data is distributed according to the normal principle. Offered analytical dependency ratios between the disintegrate curve parameters and modified plasticity criteria. Counted correlation analysis appropriate rejection of materials (in typical range). This means that in paper setted analytical relationships can be used for equipment preliminary calculation of durability and reliability.
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Martinsson, Matilda. "Koffeins påverkan på resultatet av ett 3000m-test : Orienteringselevers koffeinkonsumtion." Thesis, Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-6157.

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Syfte och frågeställningar: Studiens syfte var att undersöka hur prestation på 3000m, uppskattad ansträngningsnivå, medel- och maxpuls påverkades efter intag av 3mg koffein/kg. Studien undersökte även testpersonernas koffeinkonsumtion kopplat till träning och tävling. Metod: Tolv elever från orienteringsgymnasier sprang två 3000m-test med cirka en veckas mellanrum. Den ena gången sprang de med 3mg koffein/kg och den andra med placebo. Testpersonerna svarade på en enkät om sin koffeinkonsumtion till vardags och i träning- och tävlingssammanhang samt uppskattade sin ansträngning vid de båda tillfällena med Borgskalan. För att se om någon signifikant skillnad förekom inom gruppen gjordes ett t-test med Microsoft Excel (version 2016). Signifikansnivån sattes till P ≤ 0,05 och all data presenterades som medelvärden tillsammans med standardavvikelse (n=12). Resultat: Efter intag av koffein förbättrades den fysiska prestationen på 3000m signifikant (P=0,0052). Deltagarnas medelvärde förbättrades med 18,5 s. Den självskattade ansträngningen var statistiskt signifikant högre efter intag av koffein (P=0,012). Ingen statistiskt signifikant skillnad sågs på vare sig medel- eller maxpuls.Ingen av försökspersonerna använde systematiskt koffein i träning- och tävlingssammanhang för att förbättra den fysiska prestationen. En av deltagarna intog mer än 1000mg koffein under en vecka. Tre av deltagarna intog aldrig koffein, varken i träning- eller tävlingssammanhang eller i vardagen. Slutsats: Intag av 3mg koffein/kg ökar fysisk prestationsförmåga på 3000m hos orienteringsgymnasieelever. Deras självskattade ansträngningsnivå är högre efter intag av 3mg koffein/kg jämfört med placebo på ett 3000m-lopp. Resultatet kan ha påverkats av flera faktorer, framförallt yttre omständigheter, så som väder och dagsform.
Aim: The aim of this study was to investigate how 3000 m performance, self-assessed exertion, average heart rate and maximum heart rate was affected by a caffeine intake of 3mg/kg. The study also covered test subjects caffeine consumption when training and competing. Method: Twelve orienteering high school students ran two 3000 m tests circa one week apart. One experiment after 3mg/kg caffeine intake and the other occation on placebo. The test subjects also did a survey regarding caffeine consumption in everyday life, training and competition. The Borgskala was used for self-assessed exertion. Significance was assessed using a t-test in Microsoft Excel (2016 version). Significance level was set to P ≤ 0.05 and data was presented as mean ± standard error of the mean (n=12). Results: 3000 m performance was significantly increased after caffeine intake (P=0.0052). Self-assessed exertion was significantly higher after caffeine intake (P=0.012). No significant change in mean or maximum heartrate was observed. None of the test subjects used caffeine systematic to increase physical performance. One of the test subjects used more than 1000mg caffeine per average week. Three of the test subjects never used caffeine in either training, competition or everyday life. Conclusion: 3mg/kg caffeine increase 3000 m physical performance in orienteering high school students. Self-assessed exertion is higher after 3mg/kg caffeine intake compared to placebo when orienteering high school students run 3000 m. The Results may have been affected by several factors, especially extrinsic factors, like weather and incentive.
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Schmidbauer, Stephan [Verfasser], and Karin [Akademischer Betreuer] Meißner. "Effekte einer klassischen Konditionierung mit Koffein auf den Blutdruck und andere autonome Parameter / Stephan Schmidbauer ; Betreuer: Karin Meißner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1155097351/34.

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Nairn-Tallén, William, and Johan Gard. "Ungdomars konsumtion av koffeinhaltiga drycker - en enkätstudie." Thesis, Umeå universitet, Institutionen för kost- och måltidsvetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-172129.

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SammanfattningBakgrund: Energidryck och andra drycker innehållande koffein är vanligt förekommande hos tonåringar i Sverige och andra delar av världen. Mängden koffein varierar beroende på vilken produkt som konsumeras. Det finns gränsvärden där drycker måste förses med varningstext om innehållet överstiger en viss koffeinhalt. Den rekommenderade gränsen för ett säkert dagligt intag av koffein för unga är 3 mg/kg kroppsvikt.Syfte: Syftet var att undersöka konsumtion av koffein hos elever i årskurs 9 samt undersöka om intag av koffein kan kopplas samman med upplevelsen av sömn och stress. Studien syftar också till att ta reda på varför ungdomar konsumerar koffeinhaltiga drycker som energidryck.Metod: Studien genomfördes med en webbaserad enkät på elever i årskurs 9 under lektionstid. Data bearbetades i programmet IBM SPSS Statistics version 26 och analyserades med hjälp av Chi-två, T-test eller Spearman`s sambandstest. Resultat: En majoritet av respondenterna konsumerade drycker innehållande koffein. Respondenternas upplevda antal sömntimmar var lägre än rådande rekommendationer för sömn bland åldersgruppen och en majoritet av respondenterna upplevde sig stressade. Sömn och stress gick inte entydigt att koppla samman med koffeinkonsumtion i undersökningsgruppen. Det fanns ett samband mellan hur många enheter koffeinhaltig dryck som konsumerades och antal sömntimmar, ju fler konsumerade enheter desto färre upplevda sömntimmar. Den främsta anledningen till att respondenterna valde att konsumera energidryck uppgavs vara smaken. Smaken var även den främsta anledningen att låta bli.Slutsats: Ungdomar känner sig stressade och sover för lite. En hög konsumtion av koffein kan förvärra känslor som oro och stress samt påverka sömn negativt. Vuxna som verkar kring barn och unga bör ha en ökad medvetenhet kring koffein, hur konsumtionen ser ut bland tonåringar och möjliga negativa konsekvenser av ett utbrett nyttjande.
AbstractBackground: Energy drinks and other caffeinated beverages are a common occurrence with teenagers in Sweden and other parts of the world. The amount of caffeine varies depending of what kind of beverage is consumed, when the amount exceeds a threshold it needs to be a warning sign. The recommended daily intake of caffeine for teenagers is 3 mg/kg bodyweight.Objective: The study intended to examine consumption of caffeinated beverages as well as the main reason of caffeinated beverage of 9th grade students in Swedish elementary school. Furthermore, the purpose is to examine the correlation between high caffeine consumption, sleeping patterns and stress levels.Method: The study was implemented through a web-based survey that the students had to answer during their school day. The data were processed by using the program IBM SPSS Statistics version 26, later on to be analyzed using a Chi-square test, T-test and Spearman´s rank correlation coefficient.Results: Most of the respondents consumed beverages containing caffeine on a regular basis. Said respondents also had lower perceived sleep quality measured in number of hours, as well as higher amounts of perceived stress. However, the study did not find any direct correlation between consumption of caffeinated beverages and sleep quality or stress. What the study did find was a correlation between the number of hours the respondents slept and the number of caffeinated beverages that they consumed. The main reason for general energy drink consumption was found to be preference of taste. The same reason was also found to be the main contributing factor why some chose not to drink any caffeinated beverages at all.Conclusion: Teenagers have problems with both stress and sleep. In addition, high consumption of caffeine can aggravate these problems. Finally, adults need an increased awareness about caffeine and the negative effects the consumption of caffeine has on teenagers.
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Olsson, Erik. "Låga doser av koffeins påverkan på skjutprestation och stillahållningsförmåga hos luftgevärsskyttar." Thesis, Mittuniversitetet, Avdelningen för hälsovetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-34178.

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Persson, Josefine. "Natrium bikarbonats och koffeins påverkan på prestationen under upprepade sprinter hos kvinnliga basketspelare." Thesis, Mittuniversitetet, Avdelningen för hälsovetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-32707.

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Soubrier, Virginie. "Koffi Kwahulé : une voix afro-européenne sur la scène contemporaine." Paris 4, 2009. http://www.theses.fr/2009PA040141.

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Auteur dramatique, romancier et nouvelliste, Koffi Kwahulé est né en Côte d’Ivoire en 1956. Il appartient à la génération d’auteurs de la Post-Indépendance apparue sur la scène contemporaine au début des années quatre vingt dix. Revendiquant son appartenance à la diaspora noire, toutes ses pièces écrites entre 1991 et 2005 sont une exploration de la condition diasporique. Elles constituent la période jazz de son théâtre, période au cours de laquelle son écriture est inspirée par une écoute obsessionnelle des musiques de John Coltrane, Thelonius Monk, Ornette Coleman et d’autres génies de l’improvisation. L’utopie poétique de l’auteur afro-européen - effacer la séparation entre le drame et la musique - remet en question la notion même de drame, et le fait entrer en dialogue avec les autres écritures contemporaines. Mais cette écriture-jazz engage aussi le politique. Avec une radicalité puisée dans la mémoire de l’histoire noire, son théâtre-jazz interroge les conditions de possibilité d’un avenir commun
The playwright, novelist, and short story writer Koffi Kwahule was born in Ivory Coast in 1956. He belongs to a generation of Post-Independence authors that appeared on the contemporary scene in the early nineties. Claiming to be part of the black diaspora, all of his plays written between 1991 and 2005 explore the diasporic condition. These plays represent the "jazz period" of his theatrical writing, a period during which his work was inspired by obsessively listening to the music of John Coltrane, Thelonious Monk, Ornette Coleman, and other geniuses of improvisation. The poetic utopia of the Afro-European writer - to erase the divide between drama and music - questions the notion of drama itself and encourages a dialogue between other contemporary texts. But this form of « written jazz » also takes a political stance. With a radicalness drawn from memories of black history, Kwahule’s jazz theatre examines the conditions necessary for a future common to us all
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Strube, Jakob [Verfasser], Jürgen [Akademischer Betreuer] Brockmöller, Heike [Akademischer Betreuer] Bickeböller, and Frank [Akademischer Betreuer] Konietschke. "Studie zu erblichen Einflüssen auf die Pharmakokinetik von Midazolam und Koffein / Jakob Strube. Gutachter: Jürgen Brockmöller ; Heike Bickeböller ; Frank onietschke. Betreuer: Jürgen Brockmöller." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1070686085/34.

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Gajewska, Agnieszka [Verfasser], and Paul [Akademischer Betreuer] Pauli. "Einfluss von ADORA2A Rezeptorgen Polymorphismus und Koffein auf emotionale und frühe Informationsverarbeitungsprozesse - Ein mehrstufiges Modell für die Pathogenese der Panikstörung / Agnieszka Gajewska. Betreuer: Paul Pauli." Würzburg : Universitätsbibliothek der Universität Würzburg, 2013. http://d-nb.info/103375188X/34.

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Helm, Katharina [Verfasser], Jürgen R. [Akademischer Betreuer] Reichenbach, Ralf [Akademischer Betreuer] Schlösser, and Johannes [Akademischer Betreuer] Bernarding. "MRT-Untersuchungen zum Einfluss von Koffein auf die zerebrale Physiologie mit Hilfe der suszeptibilitätsgewichteten Bildgebung (SWI) / Katharina Helm. Gutachter: Jürgen, R. Reichenbach ; Ralf Schlösser ; Johannes Bernarding." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2011. http://d-nb.info/1016683626/34.

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Cummings, Ashlee Mae. "The Shelter of Philosophy: Repression and Confrontation of the Traumatic Experience in the Works of Sarah Kofman." Oxford, Ohio : Miami University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1248976254.

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44

Homenya, Patrick Kofi [Verfasser]. "Röntgenspektroskopische Untersuchung stimuli-responsiver Koordinationsverbindungen / Patrick Kofi Homenya." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover (TIB), 2014. http://d-nb.info/1065277520/34.

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45

Coronado, Villalobos Carlos Hugo [UNESP]. "Álgebra de Espinores e novos espinores em Física." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/150120.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Na presente tese abordaremos quatro tópicos importantes: espinores, covariantes bilineares, classificação de Lounesto e o teorema da inversão. Apresentamos a construção de covariantes bilineares para o espinor Elko e mostraremos a necessidade da deformação dos elementos da base da álgebra de Clifford com a finalidade de que as identidades de Fierz-Pauli-Kofink sejam satisfeitas. Estudamos também os ingredientes principais da classificação de espinores elaborada por Lounesto. Por último, construiremos três novas classes de espinores via o teorema da inversão a partir da premissa que o covariante bilinear $J_{\mu}$ seja nulo. Como consequência desta consideração esses novos espinores não possuem a dinâmica de Dirac, haja visto que $J_{\mu}$ na teoria de Dirac representa a corrente conservada. O surgimento de apenas três novas classes de espinores é uma consequência direta da imposição de que as identidades de Fierz-Pauli-Kofink sejam satisfeitas.
The present thesis covers four important topics: spinors, bilinear covariants, Lounesto's classification and the inversion theorem. We show and explicit the construction of bilinear covariants for the Elko spinors and the necessity of deformation of the Clifford algebra basis elements in order to satisfy the Fierz-Pauli-Kofink identities. We also study the main ingredients of the classification of spinors elaborated by Lounesto. Finally, we construct three new classes of spinors via the inversion theorem from the premise that the bilinear covariant $J_{\mu}$ is null. As a consequence, these new spinors do not have usual dynamics of Dirac, have seen that $J_{\mu}$ in Dirac's theory represents the conserved current. The emergence of only three new classes of spinors is a direct consequence of the requeriment that Fierz-Pauli-Kofink's identities must hold.
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46

Siepmann, Martin, and Wilhelm Kirch. "Effects of Caffeine on Topographic Quantitative EEG." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134674.

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Despite the widespread use of caffeine as a central nervous stimulant, the central pharmacodynamic properties of the drug have not yet been conclusively evaluated in humans. The present study was undertaken to assess the acute effects of caffeine on measures of topographical quantitative electroencephalogram (EEG) in normal subjects. Ten healthy male volunteers (mean age ± SD 25 ± 4 years) received placebo and 200 mg of caffeine as powder with oral water solution (caffeine amount = 2 cups of coffee) under randomized, double-blind crossover conditions on two different occasions. Before administration and 30 min afterwards, a 17-channel quantitative EEG was recorded during relaxation with eyes open and closed (15 min each). Caffeine caused a significant reduction of total EEG power at fronto-parieto-occipital and central electrode positions of both hemispheres when the subjects kept their eyes open. Absolute power of the slow and fast alpha and slow beta activities was diminished in various regions of the brain (p < 0.05). The effect was more pronounced with the subjects keeping their eyes open than with eyes closed. It can be concluded that quantitative EEG is a sensitive method to assess the effects of psychostimulants on the human brain. Therefore, in pharmaco-EEG studies, environmental factors such as caffeine have to be excluded
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich
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47

Kofer, Juliane Verfasser], and Roland [Akademischer Betreuer] [Lauster. "Human IgG+ Plasma Cells in Patients with Systemic Lupus Erythematosus / Juliane Kofer. Betreuer: Roland Lauster." Berlin : Universitätsbibliothek der Technischen Universität Berlin, 2011. http://d-nb.info/101494628X/34.

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48

Le, Guen Fanny. "Belles de Jazz. Voix et violence des figures féminines dans le théâtre de Koffi Kwahulé." Thesis, Paris 4, 2012. http://www.theses.fr/2012PA040221.

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Koffi Kwahulé est l'héritier d'une culture littéraire, artistique et théâtrale ivoirienne.Exilé en France depuis trente ans, son écriture s'élabore dans une tensiontransatlantique et se veut constitutive d'une mythologie contemporaine, féminine etnoire. L'ambition rhapsodique de cette dramaturgie est de déconstruire, à travers lavoix et la violence de puissantes figures féminines héritées des personnagesarchétypiques du Théâtre Ivoirien, tant le drame classique que les représentationshistoriques et culturelles qui gangrènent les relations internationales. Les figuresféminines en Belles de jazz donnent le tempo à cette dramaturgie qui comme le ThéâtreNoir nord-américain du milieu du siècle dernier, développe une rhétorique du jazz aucoeur de la mythologie de l'auteur
Koffi Kwahulé inherited from the Ivorian literary, artistic and theatrical culture.However, as he has been living in exile in France for thirty years, a transatlantictension pervades his writing and thus creates a contemporary black femininemythology. The voices and violence of powerful female figures that mirror archetypesin Ivorian Theatre, create a rhapsody dimension in this dramaturgy, which is aimed atdeconstructing the classical drama and the historical and cultural representations thatcorrupt international relations. Female figures in Belles de Jazz give the dramaturgyits tempo and make it develop into a jazz rhetorics deeply rooted into the author's ownmythology, similar to mid-twentieth century Afro American theatre
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Lim, Young Joon. "Strategic Communications of the United Nations: Case Studies of the Department of Public Information under Secretary-General Kofi Annan, 1997-2006." Ohio University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1369839088.

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50

Faupel, Annekathrin. "Charakterisierung des Bakterienspektrums der Kartoffel und dessen Potenzial zur biologischen Bekämpfung des Wurzelgallennematoden Meloidogyne incognita (Kofoid & White) Chitwood." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=97070898X.

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