To see the other types of publications on this topic, follow the link: KVV.
Dissertations / Theses on the topic 'KVV'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'KVV.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
1
Bydén, William, and David Fridlund. "Carbon Negative Heat and Power with Biochar Production : An Economic Analysis of a Combined Pyrolysis and CHP plant." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-279608.
Full textAbstract:
On the fourth of November 2016, The Paris Agreement entered into force, stating that nations worldwide should pursue efforts to limit the global temperature increase to 1,5 °C. Since then, the Intergovernmental Panel on Climate Change has specified that carbon dioxide removal, such as biochar sequestration, is necessary to achieve this goal. Biochar is a solid and porous material, rich in carbon, produced when biomass undergoes a process called pyrolysis and can, if buried in soil, sequester carbon for hundreds or even thousands of years while at the same time acting as a soil amendment. When biomass is pyrolyzed to produce biochar, a pyrolysis gas is also produced, which can be used to generate both heat and electricity. This thesis investigates if constructing and operating a plant, called a combined pyrolysis and CHP plant, which combines biochar production with heat and electricity generation, could be economically feasible and thus be an effective method for carbon dioxide removal. The findings show that constructing and operating a combined pyrolysis and CHP plant can be economically feasible. However, the economic feasibility is greatly affected by the price of biochar as a soil amendment product. The biochar market is also an undeveloped market, making price estimates of biochar far from accurate. Another factor that could significantly affect the economic feasibility of the plant is the fraction of carbon in biochar, which can be accounted for as sequestered. A higher fraction means that significantly more governmental support can be given to provide financing of the plant as well as potential revenue from carbon credits could increase. The capital cost of constructing the plant is also a factor with high uncertainty, which has a substantial effect on the economic feasibility. From this thesis, it is concluded that more research regarding the biochar market, as well as the capital costs of constructing the plant, is needed. More research could further ascertain whether or not the plant could be economically feasible and thus, an effective method for carbon dioxide removal.Den fjärde november 2016 trädde Parisavtalet i kraft vilket uppgav att länder över hela världen ska sträva efter att begränsa den globala temperaturökningen till 1,5 grader Celsius. I enlighet med detta mål har FN:s mellanstatliga klimatpanel, IPCC, specificerat att koldioxidavlägsnande åtgärder, såsom kolinlagring genom produktion av biokol, är nödvändigt. Biokol är ett fast och poröst material, rikt på kol, som produceras när biomassa genomgår en process som kallas pyrolys. Om biokol blandas ner i jord kan det binda kol i hundratals eller tusentals år samtidigt som det fungerar som jordförbättrare. När biomassa pyrolyseras produceras också en pyrolysgas som kan användas för att generera värme och elektricitet. Det här examensarbetet undersöker om det kan vara ekonomiskt genomförbart att bygga och driva en anläggning, benämnd en kombinerad pyrolys- och kraftvärmeanläggning, som kombinerar biokolsproduktion med värme- och elproduktion för att avlägsna koldioxid från atmosfären. Resultaten från arbetet visar att det kan vara ekonomiskt genomförbart att bygga och driva en kombinerad pyrolys- och kraftvärmeanläggning. Den ekonomiska genomförbarheten påverkas dock i hög grad av priset på biokol som jordförbättringsprodukt. Marknaden för biokol är dessutom outvecklad vilket gör att priset för biokol osäkert. En annan faktor som i hög grad skulle kunna påverka den ekonomiska genomförbarheten för anläggningen är andelen kol i biokol som kan anses vara lagrad. En högre andel innebär att betydligt mer statligt stöd kan ges för att finansiera anläggningen samt att potentiella intäkter från kolkrediter kan öka. Kapitalkostnaderna för att bygga anläggningen är också en faktor med hög osäkerhet som har stor effekt på den ekonomiska genomförbarheten. Från detta examensarbete dras slutsatsen att mer forskning kring biokolsmarknaden samt kring kapitalkostnaderna för att bygga anläggningen behövs. Detta behövs för att ytterligare fastställa den ekonomiska genomförbarheten hos en sådan anläggning för att avlägsna koldioxid från atmosfären.
2
El, Haou Saïd. "Régulation des canaux potassiques cardiaques par la protéine d'accrochage SAP97." Paris 6, 2009. http://www.theses.fr/2009PA066258.
Full textAbstract:
Les canaux ioniques sont des protéines enchâssées dans la membrane cellulaire responsables de l’activité électrique, notamment au niveau cardiaque. Ces canaux sont constitués du pore canalaire mais également de nombreuses protéines partenaires. Parmi ces protéines partenaires les protéines MAGUK (Membrane Associated Guanlytate Kinase) apparaissent comme étant des éléments essentiels au bon fonctionnement des canaux ioniques cardiaques. Dans cette étude, nous avons examiné le rôle de la protéine MAGUK appelée SAP97 (Synapse Associated Protein) sur divers canaux potassiques cardiaques responsables de la repolarisation du myocarde. Nos résultats ont montré que la SAP97 régule l’expression membranaire de ces canaux dans les myocytes cardiaques. De plus, nous avons montré que la SAP97 participe à la formation d’un complexe tripartite entre les canaux Kv4 et la CaMKII. L’ensemble de ces travaux a permis de montrer les protéines MAGUK joueraient un rôle majeur dans l’organisation de complexes permettant l’organisation et le couplage de l’activité électrique avec la signalisation intracellulaire.
3
Yeung, Shuk Yin. "Pharmacological study of fluoxetine and BDS toxins on central Kv1 and Kv3 channel subfamily members." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415328.
Full text
4
Tur, Jared. "Cardiovascular regulation by Kvβ1.1 subunit." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6596.
Full textAbstract:
Heterologous expression systems such as COS-7 cells have demonstrated the profound effects of KCNAB1-3 or Kvβ1-3 proteins on voltage gated potassium channels (Kv) channels. Indeed, in the presence of these β-subunits transiently expressed Kv channels are often modulated in multiple ways. Kv channel membrane expression is often increased in the presence of β-subunits. In addition, non-inactivating Kv currents suddenly become fast-inactivating and fast-inactivating channels become even faster. While much research has demonstrated the profound effects the β-subunits in particular the Kvβ1 subunit have on transiently expressed Kv currents little to date is known of the physiological role it may play. One study demonstrated that by “knocking out” Kvβ1 cardiomyocyte current changes were noted including a decrease in the Ito,f current. While this novel finding demonstrated a key cardiac physiological role of the Kvβ1 subunit it left many unanswered questions as to determine the cardiovascular regulation the Kvβ1 subunit provides. Indeed, cardiac arrhythmias and other electrical abnormalities within the heart such as long QT present patients with many unfortunate unknowns. Many of these incidences occur often abruptly with cardiac electrical abnormalities. Genetic research has begun to shine light on key cardiovascular genes in particular those coding for ion channels and auxiliary subunits or β-subunits. Kv channels and their β-subunits have gained particular notoriety in their key responsibility in restoring the resting membrane potential known as the repolarization phase. Indeed genetic manipulation and physiological examination of Kv channels and recently their β-subunits has demonstrated profound physiological results including prolonged QT durations within mice altered functional activity during physiological cycles such as estrus. While initial findings of Kvβ1 have demonstrated profound cellular and cardiomyocyte current alterations much still remains unknown. Therefore, this work hypothesizes that the Kvβ1 subunit provides a profound cardiovascular role in regulation and redox sensing at the physiological and pathophysiological level in both males and females. This work identifies a sex-based difference in cardiovascular regulation by Kvβ1 as well as demonstrated a profound redox sensing ability during altered metabolic states seen in pathophysiological conditions.
5
Sparrenbom, Charlotte Jönsson. "Constraining the southern part of the Greenland Ice Sheet since the Last Glacial Maximum from relative sea-level changes, cosmogenic dates and glacial-isostatic adjustment models." Lund : Department of Geology, GeoBiosphere Science Centre, Lund University, 2006. http://www.geol.lu.se/kvg/avhandlingar/cs_kappa.pdf.
Full text
6
Andersson, Carl Fredrik. "50 kVA eller 100 kVA : En teknisk och ekonomisk jämförelse av distributionstransformatorer." Thesis, Högskolan Väst, Institutionen för ingenjörsvetenskap, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-2730.
Full textAbstract:
Rapporten utreder om distributionstransformatorer med märkeffekten 50 kVA i Vattenfall Eldistribution AB:s elnät kan avskaffas till förmån för märkeffekten 100 kVA. Transformatorer med märkeffekten 50 kVA förekommer vid nedtransformering av spänningen från 22 kV och 11 kV till hushållens huvudspänning 0,4 kV. 50 kVA-transformatorer skiljer inte särskilt mycket från transformatorer med den högre märkeffekten i fråga om storlek och pris, och de bedöms kunna bytas ut utan större praktiska svårigheter. Fördelen med 100 kVA är att de elektriska belastningsförlusterna blir lägre i och med den högre märkeffekten. Dessutom innebär ett byte vissa elkvalitetsförbättringar. Nackdelarna med 100 kVA är att de elektriska tomgångsförlusterna är högre och att inköpspriset är högre än för 50 kVA. I övrigt kan kostnaderna likställas för de två alternativen. Endast kostnader för aktiva effektförluster berördes i rapporten då de ekonomiska kostnaderna för reaktiva effektförluster kunde försummas för de aktuella transformatorerna. För att nå ett svar på frågan om det kan vara lönsamt att avskaffa 50 kVA-transformatorerna studerades fem verkliga fall i Vattenfalls svenska elnät. Dessutom studerades eventuella elkvalitetsvinster med ett byte. Svaret blev att inte för något av de fem studerade fallen var det lönsamt med ett byte till 100 kVA-transformator. Rörande elkvalitetsaspekten blev svaret att ett byte visserligen innebär en skillnad men att andra faktorer oftast har större betydelse. Rapportens rekommendation blev att behålla 50 kVA-transformatorn i distributionsnätet.
7
Rauber, Daniel Walter. "Die Freizügigkeit nach KVG /." [S.l.] : [s.n.], 1985. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
Full text
8
Marschall, Felix [Verfasser]. "Entwicklung eines Röntgenmikroskops für Photonenenergien von 15 keV bis 30 keV / Felix Marschall." Karlsruhe : KIT Scientific Publishing, 2014. http://www.ksp.kit.edu.
Full text
9
Meurs, Renée Helene van. "De odyssee van klassieke culturele vorming (KCV) de implementatie van KCV nader beschouwd /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn//.
Full text
10
Kwon, Soonsik. "Low regularity problems of the fifth-order KdV and the modified KdV equations." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1619605911&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Full text
11
Dag, Huseyin. "A Class Of Super Integrable Korteweg-de Vries Systems." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/4/1079854/index.pdf.
Full textAbstract:
In this thesis, we investigate the integrability of a class of multicomponent
super integrable Korteweg-de Vries (KdV) systems in (1 + 1) dimensions in the
context of recursion operator formalism. Integrability conditions are obtained
for the system with arbitrary number of components. In particular, from these
conditions we construct two new subclasses of multicomponent super integrable
KdV systems.
12
Fogaça, David Augaitis. "Ondas na matéria nuclear." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-05102009-084141/.
Full textAbstract:
Assumindo que a matéria nuclear seja um fluido perfeito, estudamos a propagação de perturbações na densidade bariônica. A equação de estado é obtida através de um modelo relativístico em campo médio, o qual é uma variante do modelo não-linear de Walecka. A expansão das equações de Euler e da continuidade na hidrodinâmica relativística em torno das configurações de equilíbrio nos levam a equações diferenciais para a perturbação na densidade. Resolvemos tais equações numericamente para perturbações lineares e esféricas mediante pulsos iniciais. Para perturbações lineares econtramos soluções solitônicas de pulsos isolados e soluções com vários solitons seguidas de ``radiação\'\'. Dependendo da equação de estado um forte amortecimento pode ocorrer. Consideramos também a evolução de perturbações em um meio sem efeitos dissipativos. Nesse caso observamos a formação e quebra de ondas de choque. Depois estudamos todo o formalismo na matéria nuclear em temperatura finita. Nossos resultados podem ser relevantes para análise de dados do RHIC. Eles sugerem que ondas de choque formadas na fase de plasma de quarks e gluons podem sobreviver e se propagar na fase hadrônica. Também estudamos a equação de onda não-linear para perturbações na densidade bariônica e densidade de energia no plasma de quarks e gluons (QGP). Sob certas condições solitons podem existir no QGP. Finalmente discutimos métodos alternativos de soluções de equações di-ferenciais não-lineares.Assuming that nuclear matter can be treated as a perfect fluid, we study the propagation of perturbations in the baryon density. The equation of state is derived from a relativistic mean field model, which is a variant of the non-linear Walecka model. The expansion of the Euler and continuity equations of relativistic hydrodynamics around equilibrium configurations leads to differential equations for the density perturbation. We solve them numerically for linear and spherical perturbations and follow the propagation of the initial pulses. For linear perturbations we find single soliton solutions and solutions with one or more solitons followed by ``radiation\'\'. Depending on the equation of state a strong damping may occur. We consider also the evolution of perturbations in a medium without dispersive effects. In this case we observe the formation and breaking of shock waves. We study all these equations also for matter at finite temperature. Our results may be relevant for the analysis of RHIC data. They suggest that the shock waves formed in the quark gluon plasma phase may survive and propagate in the hadronic phase. We also study the non-linear wave equation for pertubations in baryon density and energy density in quark-gluon-plasma (QGP). Under certains conditions solitons may exist in QGP. Finally we discuss alternatives methods for solving non-linear differential equations.
13
Fogaça, David Augaitis. "Solitons em colisões núcleon-núcleo." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-24032009-003904/.
Full textAbstract:
Supondo que o núcleo possa ser tratado como um fluido perfeito, nós estudamos as condições para a formação de solitons de Korteweg-de Vries (KdV) na matéria nuclear. A existência de solitons de KdV depende da equação de estado nuclear que, por sua vez, depende da teoria microcóspica subjacente da interação núcleon-núcleon e das aproximações feitas durante os cálculos. No nosso trabalho, nós retomamos estudos sobre solitons no núcleo feitos no passado e substituímos a equação de estado usada anteriormente por outra mais moderna e mais realista, baseada no modelo de Walecka e suas variantes. Nossa análise mostra que solitons de KdV podem ser formados no interior do núcleo com largura em torno de um a dois fermis.Assuming that the nucleus can be treated as a perfect fluid we study the conditions for the formation and propagation of Korteweg-de Vries (KdV) solitons in nuclear matter. The existence of these solitons depends on the nuclear equation of state, which, in its turn, depends on the underlying microscopic theory of the nucleon-nucleon interaction and also on the approximations used in the calculations. In this work we reexamine early works on nuclear solitons, replacing the old equations of state by others, more modern and more realistic, base on QHD and on its variants. Our analysis shows that KdV solitons may indeed be formed in the nucleus with a width around one and two fermis.
14
Eid, Basma. "The pharmacology & therapeutic potential of Kv7 channels in the pulmonary circulation." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/the-pharmacology--therapeutic-potential-of-kv7-channels-in-the-pulmonary-circulation(6a9bb4a3-eb2a-4135-91b2-ca598f041f86).html.
Full textAbstract:
Pulmonary arterial tone is regulated in part by the membrane potential (Em) of pulmonary artery smooth muscle cells (PASMCs). The Kv7 family of K+ channels was recently implicated in regulating Em in rat PASMCs and expression of KCNQ1, KCNQ4 and KCNQ5 mRNA, which encode Kv7 channels, was reported. Kv7 activators were beneficial in two-independent mouse models of pulmonary hypertension (PH), which provides further evidence for their role in regulating pulmonary tone. The goals of this study were to: 1) Elucidate the role of Kv7 channels and Em in the hypertensive pulmonary circulation and 2) Study the effects and mechanism of action of a novel Kv7 modulator, zinc pyrithione (ZnPy) on the pulmonary circulation. PH was induced in male Wistar rats by administering a single 60 µg/kg intraperitoneal injection of monocrotaline (MCT). The effects of Kv7 modulators on hypertensive and control pulmonary arteries (PA) were compared using small-vessel myography. The vasoconstrictor effect of the Kv7 blocker, XE991, was enhanced in MCT PA. The Kv7 activators retigabine and ZnPy showed enhanced efficacy in relaxing MCT PA and suppressed raised intrinsic tone identified in MCT PA relative to control PA. The effects of MCT in responses to Kv7 modulators were pulmonary specific as they were not seen in mesenteric arteries from the same animals. Real-time PCR studies revealed that PA from MCT and control rats showed a similar expression of KCNQ1, KCNQ4 and KCNQ5 mRNA transcripts. I propose that the enhanced effects of Kv7 modulators on PA from MCT rats were due to disease-induced depolarization of PASMCs, which raised intrinsic tone and increased Kv7 channel activation at rest. This is the first evidence that Kv7 channels are functional in this model of PH and may serve as potential drug targets. The effects of ZnPy on PASMCs were studied by patch-clamp electrophysiology. ZnPy consistently hyperpolarized PASMCs and significantly increased the K+ current elicited by a voltage-step from -80 to +40 mV. ZnPy also increased the non-inactivating current recorded at 0 mV in some cells. The effects of ZnPy on Em and K+ currents were inhibited by 10 mM tetraethylammonium (TEA) and 1 µM paxilline but not by 50 nM iberiotoxin. XE991 (10µM) inhibited the ZnPy-induced hyperpolarization without altering its effects on K+ currents, suggesting that the current recorded was not responsible for its effect on Em. When tested on intact vessels, ZnPy consistently produced vasodilation. Its effects were unaffected by TEA, paxilline and iberiotoxin; however, XE991 (100 nM) had an inhibitory effect. The results suggest that ZnPy hyperpolarizes PASMCs by activating a TEA, paxilline and XE991 sensitive, but iberiotoxin insensitive channel, most likely a Kv7 channel. Its ability to dilate PA depended on pharmacologically distinct mechanisms, which are unlikely to involve Kv7 channels.
15
Pavlou, Petro. "KVA in Black Scholes Pricing." Master's thesis, Faculty of Commerce, 2019. http://hdl.handle.net/11427/30880.
Full textAbstract:
The post 2007-financial crisis era has led to renewed zeal in quantifying market incompleteness when pricing contingent claims. This quantification exercise is necessary in maintaining a stable and sustainable banking operation and thus the XVAs have emerged as the metrics for market incompleteness. This dissertation focuses solely on the capital valuation adjustment (KVA) and aims to use the definition of KVA as set out by Albanese et al. (2016) in an investigation of different numerical techniques for calculating KVA. A single equity forward is considered first, followed by an equity option and then portfolios of options on two underlying assets, with the dissertation ending by considering a practical example on discrete delta and vega-delta hedging an index option. The numerical approaches explored are the binomial tree method and a combination of the crude and quasi-Monte Carlo method.
16
Antonsen, Carolina. "Surface scattering using KeV ions." Thesis, University of Ottawa (Canada), 1989. http://hdl.handle.net/10393/5393.
Full text
17
Kourrich, Saïd. "Rôle des canaux Kv1. 1 et Kv1. 3 au cours des processus mnésiques chez le rat." Aix-Marseille 1, 2001. http://www.theses.fr/2001AIX11037.
Full textAbstract:
Les expériences rapportées dans ce mémoire avaient pour but d'étudier le rôle des canaux KV1. 1 et KV1. 3 au cours des processus d'apprentissage et de mémoire. Dans la première approche (comportementale), l'effet du blocage de ces canaux par la KTX (10 ng) (en injection icv) a été évalué dans différents protocoles mettant en jeu préférentiellement deux types de mémoire dans une tâche de discrimination olfactive : la mémoire procédurale et la mémoire de référence. Dans les deux types de mémoire étudiée, le blocage de ces canaux par la KTX facilitait l'apprentissage et non la consolidation des informations. Cette toxine facilitait également le rappel à long-terme d'une association odeur-renforcement. Une expérience contrôle en open-field a montré que le blocage des canaux KV1. 1 et KV1. 3 par la KTX n'affectait pas les processus d'attention. La deuxième approche (électrophysiologique) avait pour but d'explorer les éventuels phénomènes de plasticité pouvant sous-tendre la facilitation de l'apprentissage induit par la KTX. Une première expérience, "in vitro" sur tranche d'hippocampe, a montré que la KTX (100 nM) induisait une facilitation synaptique de longue durée vraisemblablement par un mécanisme pré-synaptique au niveau des synapses fibres moussues-CA3. Ce résultat a été ensuite confirmé par une expérience réalisée "in vivo" chez le rat éveillé libre de ses mouvements avec une dose de 10 ng en icv. La troisième approche (histochimique) avait pour but d'observer une éventuelle implication de ces canaux au cours des processus mnésiques. La technique d'hybridation in situ a montré une diminution de l'expression des ARNm KV1. 1 au niveau de l'hippocampe ventral (GD, CA3 et CA1) lorsque les rats étaient sacrifiés 1 heure après la seconde séance d'apprentissage d'une association odeur-renforcement. D'autres variations ont été observées, mais ne semblaient pas être spécifiques du conditionnement.
18
Cao, Bo. "Supernova Bound on keV Sterile Neutrinos." Thesis, KTH, Teoretisk fysik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-140201.
Full text
19
McCarthy, Oscar Daniel. "Dispersionless integrable systems of KdV type." Thesis, University of Hull, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395435.
Full text
20
Hesse, Mario, Oliver Lück, Matthias Redlich, and Oliver Rottmann. "Empirischer Vergleich von KBV und ÖPP." Universitätsbibliothek Leipzig, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-223012.
Full textAbstract:
Seit einigen Jahren erfolgt in Deutschland eine verstärkte Einbindung von privatwirtschaftlichen Akteuren bei der Bereitstellung öffentlicher Leistungen. Insbesondere im Bereich der Infrastrukturbereitstellung haben sich Öffentlich-Private-Partnerschaften als eine alternative Beschaffungsvariante etabliert. Diese Vertrags-ÖPP sind in den Kontext einer allgemeinen Privatisierungskritik geraten, vor allem wird die Wirtschaftlichkeit dieser Variante bzw. deren Berechnung diskutiert. Vor diesem Hintergrund liegt das Ziel der Studie darin, die geringe empirische Datenlage zum Status quo der Umsetzungspraxis zu vergrößern, die Beschaffungsalternativen konventionelle Beschaffungsvariante (KBV) und ÖPP komparativ gegenüberzustellen und dabei auch auf Aspekte einzugehen, die im Erfahrungsbericht der Rechnungshöfe nicht behandelt werden, da dieser ausschließlich die Wirtschaftlichkeit von ÖPP fokussiert. Der Untersuchungsgegenstand
fokussiert nur kommunale ÖPP-Projekte die einen Lebenszyklusansatz verfolgen, folglich Infrastruktureinrichtungen wie Schulen, Kindertagestätten und Verwaltungsgebäude. Allen diesen Projekten ist inhärent, dass während der Vertragslaufzeit kein öffentliches Eigentum veräußert wird, die Aufgabenverantwortung folglich stets bei der öffentlichen Hand verbleibt und somit auch keine Privatisierung öffentlichen Eigentums erfolgt. Die Studie zeigt, dass bei vielen KBV-Projekten die Betriebskosten in den anfänglich zu erstellenden Wirtschaftlichkeitsvergleichen keine oder nur eine untergeordnete Rolle spielen, während bei ÖPP in der Regel von Anfang an der gesamte Lebenszyklus der Infrastruktureinrichtung betrachtet wird, da der Großteil der Gesamtkosten der Infrastrukturmaßnahme während der Betriebsphase anfällt. (Kostensparende) Synergieeffekte bleiben deshalb bei den KBV vielfach ungenutzt. Die Nutzung von ABC-Ausschreibungen löst dieses Problem nur bedingt, da durch sie Aufwand und Transaktionskosten enorm gesteigert werden. Die Betrachtung unterschiedlicher Wertschöpfungsstufen (Planung, Bau, Finanzierung, Betrieb, Verwertung) stellt den entscheidenden Punkt für die Wirtschaftlichkeit von ÖPP-Projekten im Vergleich zur KBV dar, da die private Seite veranlasst ist, die Bauleistungen betriebsoptimierend zu planen und durchzuführen. Ferner zeigt die Studie, dass die von den Rechnungshöfen angemahnte Verfahrenstransparenz eine Herausforderung bei allen öffentlichen Beschaffungsvarianten darstellt und das Fehlanreize, die durch die Prinzipal-Agent-Problematik entstehen, ebenfalls kein singuläres Defizit des ÖPP-Ansatzes sind. Dem Vorwurf, dass ÖPP-Projekte dazu genutzt würden, Schulden in öffentlichen Haushalten zu verschleiern und Kosten möglichst intransparent darzustellen, wird mit der schrittweisen bundesweiten Umstellung der Kommunen auf doppische Haushaltsführung weitestgehend der Boden entzogen, da ÖPP-Projekte mit Forfaitierung sogar Transparenzvorteile gegenüber den KBV aufweisen. Ziel der Studie ist nicht, die ÖPP als „Königsweg“ der öffentlichen Beschaffung darzustellen, sondern den Versuch zu unternehmen, einen kritischen Blick auf die Beschaffungsvariante selbst und die an ihr geäußerte Kritik zu werfen. Es gilt: Vor dem Hintergrund der langfristigen Bindung des privaten Partners und der damit verbundenen Verantwortungs- und Risikoteilung ist es nach wie vor möglich, dass wirtschaftlichere und bedarfsgerechtere Lösungen als bei der KBV gefunden werden.
21
Chandolias, Pavlos. "Diesel from wood biomass : Screening LCA of a proposed KDV-plant in Jämtland, Sweden." Thesis, Mittuniversitetet, Avdelningen för ekoteknik och hållbart byggande, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-25508.
Full textAbstract:
The KDV-process uses catalytic depolymerisation to convert biomass into diesel oil. The environmental performance of KDV-diesel in a proposed KDV-plant located in the County of Jämtland, Sweden, was assessed using Life Cycle Assessment (LCA) methodology. The functional unit of the study was one litre of KDV-diesel and the environmental impact categories that were considered were Global Warming Potential (GWP), Eutrophication Potential (EP) and Acidification Potential (AP). The acquisition of wood biomass significantly affected the life cycle performance of KDV-diesel production in all three impact categories. When benchmarked against conventional diesel oil, KDV-diesel contributed significantly less to GWP, since there are no fossil carbon dioxide (CO2) emissions from the use phase, but it contributed more to EP and AP due to slightly higher emissions in the production phases. This conclusion holds true for five investigated electricity-supply scenarios for the production of KDV-diesel. Each scenario utilised a different source for electricity production: wind power; hydro power; nuclear power; coal power; and using part of the produced KDV-diesel for on-site electricity production. Another scenario analysis compared an alternative use of the wood biomass and assumed that the same amount of wood biomass was used to generate bio-electricity, instead of being converted into KDV-diesel. The scenario analysis indicated that whether wood biomass should be used for KDV-diesel production or for bio-electricity production depends on the type of electricity that is used throughout the life cycle of KDV-diesel.KDV-processen använder katalytisk depolymerisering för att omvandla biomassa till dieselolja. Miljöprestanda för KDV-diesel från en föreslagen KDV-anläggning i Jämtland län, Sverige, har studerats med livscykelanalys (LCA) metodik. Studiens funktionella enhet var en liter av KDV-diesel och de studerade miljöpåverkanskategorierna var Klimatpåverkan (GWP), Övergödning (EP) och Försurning (AP). Skogsbruket påverkade signifikant livscykelprestanda för KDV-dieselproduktion från trädbiomassa i de tre studerade miljöpåverkanskategorierna. Kontrasterad mot konventionell dieselolja bidrog KDV-diesel betydligt mindre till GWP eftersom det inte finns några utsläpp av fossil koldioxid (CO2) under användningsfasen, men bidrog samtidigt mer till EP och AP på grund av något högre utsläpp i produktionsfasen. Denna slutsats gäller för fem olika elförsörjning scenarier för produktion av KDV-diesel som studerats. Varje scenario använde olika typ av elproduktion: vindkraft; vattenkraft; kärnkraft; kolkraft; samt att använda en del av den producerade KDV-diesel för egen elproduktion. En annan scenarioanalys studerade alternativ användning av trädbiomassan och antog att samma mängd träbiomassa användes för att generera bio-elektricitet istället för KDV-diesel. Scenarioanalysen visade att utfallet för ifall träbiomassan borde användas för produktion av KDV-diesel eller bio-electricitet beror på typen av elproduktion som används för KDV-diesels livscykel.
Η διαδικασία KDV χρησιμοποιεί καταλυτικό αποπολυμερισμό για τη μετατροπή βιομάζας σε καύσιμο ντίζελ. Οι περιβαλλοντικές επιδόσεις του KDV-ντίζελ σε μια προτεινόμενη μονάδα KDV που βρίσκεται στην περιφέρεια Γιέμτλαντ της Σουηδίας, αξιολογήθηκαν με τη μέθοδο Αξιολόγησης του Κύκλου Ζωής (LCA). Η λειτουργική μονάδα της μελέτης ήταν ένα λίτρο KDV-ντίζελ και οι κατηγορίες περιβαλλοντικών επιπτώσεων που εξετάστηκαν ήταν το Δυναμικό Θέρμανσης του Πλανήτη (GWP), το Δυναμικό Ευτροφισμού (EP) και το Δυναμικό Οξίνισης (AP). Η απόκτηση της βιομάζας ξύλου επηρέασε σημαντικά την απόδοση του κύκλου ζωής της παραγωγής KDV-ντίζελ και στις τρεις κατηγορίες περιβαλλοντικών επιπτώσεων. Σε σύγκριση με το συμβατικό πετρέλαιο ντίζελ, το KDV-ντίζελ συνέβαλε σημαντικά λιγότερο στο GWP, δεδομένου ότι δεν υπάρχουν εκπομπές διοξειδίου του άνθρακα (CO2) ορυκτής προέλευσης κατά τη φάση της χρήσης, αλλά συνέβαλε περισσότερο στο EP και στο AP λόγω ελαφρώς υψηλότερων εκπομπών στις φάσεις της παραγωγής. Το συμπέρασμα αυτό ισχύει για πέντε σενάρια παροχής ηλεκτρισμού για την παραγωγή του KDV-ντίζελ που μελετήθηκαν. Σε κάθε σενάριο χρησιμοποιήθηκε μια διαφορετική πηγή ενέργειας για την παραγωγή ηλεκτρισμού: αιολική ενέργεια, υδροηλεκτρική ενέργεια, πυρηνική ενέργεια, ηλεκτροπαραγωγή με καύση άνθρακα και χρήση μέρους του παραγόμενου KDV-ντίζελ για επιτόπια παραγωγή ηλεκτρισμού. Μια διαφορετική ανάλυση σεναρίου συνέκρινε μια εναλλακτική χρήση της βιομάζας ξύλου, υποθέτοντας ότι η ίδια ποσότητα βιομάζας ξύλου χρησιμοποιήθηκε για την παραγωγή βιο-ηλεκτρισμού, αντί να μετατραπεί σε KDV-ντίζελ. Η ανάλυση σεναρίου κατέδειξε ότι η χρήση της βιομάζας ξύλου για την παραγωγή KDV-ντίζελ ή για την παραγωγή βιο-ηλεκτρισμού εξαρτάται από την πηγή ενέργειας που χρησιμοποιείται για την παραγωγή ηλεκτρισμού καθ’όλη τη διάρκεια του κύκλου ζωής του KDV-ντίζελ.
22
Rose, Andrew. "Numerical simulations of the stochastic KDV equation /." Electronic version (PDF), 2006. http://dl.uncw.edu/etd/2006/rosea/andrewrose.pdf.
Full text
23
Ter-Braak, Floris. "Perturbed KdV equations and their integrability properties." Thesis, Durham University, 2018. http://etheses.dur.ac.uk/12550/.
Full textAbstract:
In this thesis we investigate the integrability properties of the regularized long-wave (RLW) equation and modified regularized long-wave (mRLW) equation as perturbations of the integrable Korteweg-de Vries (KdV) equation. We study various properties of numerical mRLW three-soliton scattering and compare these with the corresponding RLW soliton solutions. We find that the numerical mRLW solitons behave much like integrable solitons in the sense that the only result of the three-soliton interaction is the phase shift each soliton experiences, which is approximately equal to the sum of pairwise phase shifts. Furthermore, we investigate the so-called quasi-integrability properties of these RLW and mRLW simulations. Using both analytical and numerical methods, we argue that these models possess an infinite amount of asymptotically conserved charges, i.e., quasi-conserved charges, which are observed in multi-soliton interactions. Finally, we also simulate numerical RLW and mRLW solutions in the presence of additional perturbing terms. This allows us to study soliton-radiation interactions and we find that for certain perturbations, these interactions preserve the quasi-conservation laws to a certain extend.
24
Yvernault, Jean-Baptiste. "Etude des perturbations hamiltonienne[s] de KdV." Paris 6, 2002. http://www.theses.fr/2002PA066564.
Full text
25
Jezbera, Lukáš. "KMV model v podmínkách českého kapitálového trhu." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-75355.
Full textAbstract:
The thesis is focused on the options of quantifying credit risk by using the concept of the KMV model. The introduction outlines the basic approaches to measuring credit risk. In the following chapters is specified the nature of KMV model with the focus on its application in the Czech capital market. Self-calibration of the KMV model is made in this part. The analytical part related to the quantification of credit risk using the KMV model is implemented on selected companies which are traded on the Prague Stock Exchange. The results obtained are consequently confronted with the official rating degrees of agency Moody's.
26
SILVA, Luís Eduardo Tenório. "Análise do impacto do isolamento em ambientes virtuais." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/20267.
Full textAbstract:
Submitted by Luiza Maria Pereira de Oliveira (luiza.oliveira@ufpe.br) on 2017-08-04T14:28:42Z
No. of bitstreams: 2
license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5)
DISSERTAÇÃO Luiz Eduardo Tenório Silva.pdf: 1078029 bytes, checksum: 3ffaed1682082ec2d37b84b496c3cd81 (MD5)Made available in DSpace on 2017-08-04T14:28:42Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Luiz Eduardo Tenório Silva.pdf: 1078029 bytes, checksum: 3ffaed1682082ec2d37b84b496c3cd81 (MD5) Previous issue date: 2016-03-07
CNPq
O surgimento da virtualização permitiu uma mudança na maneira de pensar em prestação de serviço pela Internet, permitindo assim o surgimento de grandes conceitos como a computação em nuvem. Com o passar do tempo, novas tecnologias que permitem virtualizar recursos foram surgindo e trouxe a tona questões de desempenho, isolamento, entre outras. Analisar o impacto causado pelo mau comportamento das abstrações virtuais pode permitir ao administrador da nuvem tomar uma ação na escolha de uma tecnologia específica de virtualização para minimizar os impactos causados a todo ambiente. Hodiernamente, o isolamento é uma preocupação que remete pesquisas e estudos do seu impacto na qualidade dos serviços prestados em um ambiente virtualizado. Indagar sobre a possibilidade de detecção para tomada de ações com a finalidade de minimizar os impactos decorrentes de interferências devido a um mau isolamento é uma das atividades que vêm sendo estudadas com o passar dos anos. O surgimento de diversas técnicas de virtualização trouxe também preocupações de qual é adequada a qual caso. Alguns dessas técnicas vêm sofrendo melhorias únicas nesses últimos anos, principalmente no que diz respeito ao isolamento e controle de recursos. Nesse contexto, essa dissertação propõe uma estratégia adaptada da literatura (procurando unir técnicas distintas) para observar possíveis indícios de quebra do isolamento de ambientes virtuais e organizar os serviços de determinada natureza na melhor técnica de virtualização, verificando também os resultados apresentados por cada técnica de virtualização existente. Para tanto, é adotada uma metodologia que favorece a concepção dos diversos cenários possíveis a partir de um número de infraestruturas virtuais, ofertando serviços web e utilizando diferentes técnicas de virtualização, observando principalmente os recursos utilizados pelas infraestruturas virtuais e a qualidade do serviço prestado. Concluímos que dependendo do tipo de recurso observado as estratégias de isolamento de uma técnica de virtualização podem ser ou não eficazes.
The rise of virtualization has enabled a shift in thinking in service delivery over the Internet, thus allowing the emergence of major concepts such as cloud computing. Over time, new technologies that enable virtualization resources have emerged and brought up performance issues, performance, insulation, etc. Analyze the impact of the bad behavior of virtual abstractions can enable the cloud administrator take an action in choosing a specific virtualization technology to minimize impacts to the whole environment. Nowadays, isolation is a concern that brings research and studies its impact on the quality of services in a virtualized environment. Investigate about the possibility of detection for taking actions in order to minimize the impacts of interference due to poor isolation, it is one of the activities that have been studied over the years. The emergence of various virtualization techniques also brought concerns the kind which is suitable case. Some of these techniques have improved in recent years, especially with regard to isolation and control features. In this context, this work proposes an adapted strategy literature (seeking to unite different techniques) to observe possible break indications isolation of virtual environments and organize the particular nature services in the best virtualization technique, also checking the results presented for each technique existing virtualization. Therefore, a methodology that favors the design of the various possible scenarios constructed from a number of virtual infrastructures offering web services and using different virtualization techniques is adopted, especially noting the resources used by the virtual infrastructure and the quality of service. We conclude that depending on the type of resource noted the isolation strategies of a virtualization technique can be effective or not.
27
G, Glebov S., and Kiselev O. M. "The forced KdV equation and passage through resonance." Universität Potsdam, 2005. http://opus.kobv.de/ubp/volltexte/2009/2997/.
Full textAbstract:
We construct a special asymptotic solution for the forced KdV equation. In the frame of the shallow water model this kind of the external driving force is related to the atmospheric disturbance. The perturbation slowly passes through a resonance and it leads to the solution exchange. The detailed asymptotic description of the process is presented.
28
Pérez, Verdaguer Mireia. "Deciphering the interaction between Kvl.3 and Caveolin." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/291827.
Full textAbstract:
The voltage-dependent K+ channel Kv1.3 participates in many physiological events like proliferation and activation of immunitary cells, membrane repolarization in sensory neurons, vascular smooth muscle tone, insulin resistance and obesity. In most cases, Kv1.3 concentrates in specific membrane microdomains called lipid rafts. These domains act as platforms where signaling pathways converge. Caveolae are a specialized form of lipid rafts with an omega shaped structure build up by the structural protein caveolin. These omega shaped structures are present in multiple cell lines and highly abundant in adipocytes where they account for up to 30 % of the plasma membrane surface, where they participate in lipid transport, lipotoxicity protection, mechanic stress protection and cell signaling. Evidence indicates that Kv1.3 functionality relays not only on expression but also on localization at the plasma membrane. The importance of this spatial regulation is manifest when an altered Kv1.3 distribution is related with the appearance of disease. Therefore, the mechanisms that govern Kv1.3 function are of considerable interest. In this study we characterized the relationship between Kv1.3 and caveolins. Thus Kv1.3 interacted mainly with caveolin 1. In addition, we analyzed the presence of putative caveolin-binding domain in Kv1.3 that could explain their interaction. To that end, we performed structure-function studies by using a repertoire of Kv1.3 mutants and stable HEK-293 cell lines with or without caveolins, characterized putative interactions and analyzed membrane dynamics by single molecule tracking. Thus, a CBD appeared in the Nt of the Kv1.3 (close to the T1 domain). This motive was not only involved in Kv1.3-caveolin interaction but also in Kv1.3 forward trafficking. Thus the Kv1.3mutCBD remained trapped in intracellular Golgi-like structures. Even so, the channel remained functional despite some biophysical properties alterations. Moreover, the channel suffered palmitoylation like Kv1.5 but, unlike Kv1.5 it was not the mail lipid raft targeting signal as it was caveolin. 2 palmitoilation sites would be involved in Kv1.3 palmitoylation. C51/52, C267 and C515.
The role of Kv1.3 in adipocytes raises an important debate as it has been proposed that Kv1.3 could be a pharmacological target in obesity. What is more, Kv1.3 (-/-) mice presented a lean phenotype that could suggest the importance of the Kv1.3 in preadipocytes proliferation and differentiation. We have characterized the presence of Kv1.3 in rat, mice and human adipocytes and before and after adipogenesis induction of 3T3-L1 cell line. the adipogenesis induced caveolin 1 expression and a parallel Kv1.3 increase. Since adipogenesis induced both Kv1.3 and caveolin 1 expression and so the appearance of caveolae, we further analyzed the specific localization of Kv1.3. Our results indicate that adipogenesis triggers a relocalization of Kv1.3 in newly synthesized caveolae. Because most of insulin-dependent adipocyte signaling is located in these structures the presence of the channel in caveolae seemed to be important for adipocytes physiology. What is more, the caveolin expression disruption relocated Kv1.3 out of lipid raft caveolae structures. As Kv1.3 is considered an important pharmacological target for different autoimmunitary diseases and obesity, it is important to bring light to the Kv1.3 interactions with other partners that can regulate channel surface distribution and function.El canal de potassi dependent de voltatge Kv1.3 està involucrat en múltiples funcions cel·lulars. Així, el Kv1.3 participa en la fisiologia cel·lular de leucòcits, neurones sensorials, el to de la musculatura llisa vascular, resistència a insulina i obesitat. Part del Kv1.3, que es localitza majoritàriament a la membrana plasmàtica, es distribueix en microdominis lípid raft. Aquests lípid rafts actuen com a plataformes de senyalització on múltiples molècules de senyalització convergeixen per coordinar la resposta cel·lular. Un tipus especialitzat d’aquests microdominis són les caveoles. Estructures amb forma d’omega gràcies a la presència de la proteïna estructural caveolina. Són presents en diversos tipus cel·lulars i especialment abundants en adipòcits on poden suposar fins un 30% de la superfície cel·lular. En aquesta tesi hem estudiat la interacció entre el Kv1.3 i la caveolina en el sistema d’expressió heteròleg HEK 293. Així, ambdues proteïnes interaccionen a través d’un motiu CBD present al Nt del Kv1.3. La disrupció d’aquest domini aboleix la interacció entre ambdues proteïnes i, més enllà, altera el trànsit del canal a través de la ruta secretora. Així, el Kv1.3mutCBD tot i mantenir la capacitat de tetrameritzar queda retingut en estructures intracel3lulars tipus Golgi presumiblement degut a un defecte de N-glicosilació. La interacció entre el Kv1.3 i caveolina va poder ser confirmada en adipòcits. més encara, la depleció de caveolina en adipòcits 3T3-L1 deslocalitza el canal de les caveoles. Més enllà d’intervenir en la localització del canal, la caveolina també canvia l’activitat electrofisiològica del canal. Així, en absència de caveolina el canal presenta una menor densitat de corrent i la seva presència canvia lleugerament les propietats biofísiques del canal, fent més ràpides l’activació i inactivació.
29
Oliveras, Martínez Anna. "Cardiovascular Kv7 channels in health and in disease." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/385848.
Full textAbstract:
Voltage-gated K+ channels, Kv channels, are the most diverse group of K+ channels. They have several key functions in cardiovascular and nervous system; setting the resting membrane potential and controlling the repolarization of the action potential. In non-excitable cells they also play crucial role in water and ion transport across the epithelia or cell volume regulation. Such extraordinary heterogeneity in functions is closely related with a remarkable genetic and structural heterogeneity of Kv channels.
Among Kv channels, the Kv7 family comprises 5 members, Kv7.1-Kv7.5. Like other Kvs, Kv7 channels are tetramers of 4 α subunits. The topological arrangement of every α subunit consists in 6 transmembrane segments: S1-S4 form the voltage sensing domain and the S5-S6 region the ion-selective pore. Kv7 channels use to assemble as homotetramers, but most of the members of the family are also able to form heterotetrameric channels. Heterotetramerization is one of most important mechanisms to achieve the vast functional diversity that they display. Moreover, Kv7 channel function is also influenced by regulatory subunits, the KCNE family. They regulate various gating parameters, current density, channel assembly, ER retention, sorting into different traffic pathways, subcellular localization, regulation of the post-translational modifications or sensibility to pharmacological agents.
In the cardiovascular system, both Kv7.1 and Kv7.5 play a pivotal role. In cardiac myocytes, Kv7.1 homotetramers combine with KCNE1 β subunit to form functional channels. They are the molecular correlate of the IKs current, a slow delayed-rectifier K+ current involved in the repolarization of the cardiac action potential and an important determinant of the duration of the QT interval of the electrocardiogram. Mutation in either, Kv7.1 and KCNE1 result in long QT or short QT syndromes, which can lead to fatal severe arrhythmias. Kv7 have been also recognized to be key regulators of the vascular physiology, setting the resting membrane potential in vascular smooth muscle myocytes and therefore controlling the vascular smooth muscle tone. In particular, Kv7.1, Kv7.4 and Kv7.5 had been detected in numbers of veins and arteries, but the specific contribution of every subunit to physiological relevant K+ currents is still under debate.
Within this scenario, the proposed objectives for the currently discussed PhD dissertation were focused on further study the heteroligomerization process of the Kv7 channel family, either by heterotetramerization or by interaction with β regulatory subunits. In the one hand corroborate the functional assembly of Kv7.1-Kv7.5 heterotetramers in vascular smooth muscle. On the other hand, we were also committed to explore the molecular pathological mechanisms of Kv7.1 mutations linked to cardiac channelopathies as well as dissect the traffic and assembly process of the Kv7.1-KCNE1 complex.
We had been able to prove that Kv7.1-Kv7.5 form heterotetrameric channels in vascular smooth muscle cells. Moreover, upon heterotetramer assembly the special distribution of those channels within plasma membrane microdomains is rearrange and Kv7.1 shifted out of lipid raft structures. In addition, we had studied 2 different mutations in Kv7.1, F279I and D242N, responsible for short QT and long QT syndromes, respectively. Those mutations uncover 2 Kv7.1 residues important for KCNE1 interaction: F279 physically interacts with KCNE1 and D242 is involved in the KCNE1-dependent modulation of the voltage-dependent gating mechanism of the Kv7.1 channel. Furthermore, our results revealed that Kv7.1 and KCNE1 are not assembled in the very first stages of the biosynthetic pathway. On its own, KCNE1 traffics through the classical secretion pathway to the cell surface, in contrast, Kv7.1 takes an unconventional pathway. Upon co-assembly, Kv7.1 redirects KCNE1 to the unconventional pathway that lead to the concentration of both subunits in the endoplasmatic reticulum-plasma membrane junctions, where complexes are assembled.Els canals de potassi dependents de voltatge Kv7.1 i Kv7.5 juguen un paper molt important en la fisiologia del sistema cardiovascular. Aquest canals iònics estan formats per la tetramerització de 4 subunitats α. La heterotetramerizació és un dels mecanisme principals que dona lloc a la immensa diversitat funcional que mostra aquesta família. A més a més, la seva funció també es veu influenciada per la interacció amb subunitats β reguladores de la família KCNE. Tot i ser petits pèptids, els KCNEs poden modular un gran ventall de característiques de la biologia i electrofisiologia de les corrents generades per la família Kv7. En els cardiomiòcits, Kv7.1 interacciona amb KCNE1 per donar lloc el corrent IKs, una important corrent de K+ determinant per la repolarització del potencial d’acció cardíac i per la durada del interval QT de l’electrocardiograma. Mutacions tant en Kv7.1 com en KCNE1 donen lloc a les síndromes de QT llarg i QT curt, totes dues relacionades amb perilloses arítmies i mort sobtada. Kv7.1 juntament amb Kv7.4 i Kv7.5 també participen en el control del to de la musculatura llisa vascular, tot i que el paper específic de cada subunitat en les corrents detectades en aquest teixit encara genera una gran controvèrsia. En la present tesi doctoral demostrem l’existència d’heterotetramers Kv7.1-Kv7.5 en els miòcits de la musculatura llisa vascular. Aquesta nova interacció provoca el desplaçament de Kv7.1 fora dels microdominis de membrana tipus lipid raft. També hem estudiat els mecanismes patològics moleculars de dos mutacions en Kv7.1, F279I i D242N, responsables de les síndromes del QT curt i el QT llarg, respectivament. Aquestes dues mutacions han posat de manifest 2 residus en Kv7.1 importants per la interacció amb KCNE1: F279 participa en la interacció física amb KCNE1 i D242 en la regulació per KCNE1 del mecanisme, depenent de voltatge, d’obertura del canal. Per últim, hem comprovat que Kv7.1 i KCNE1 trafiquen per diferents vies secretores i que la formació dels complexes Kv7.1-KCNE1 té lloc a les unions reticle endoplasmatic-membrana plasmàtica.
30
Zabalza, de Torres Victor. "The keV-TeV connection in gamma-ray binaries." Doctoral thesis, Universitat de Barcelona, 2011. http://hdl.handle.net/10803/33649.
Full textAbstract:
Gamma-ray binaries are systems that comprise a young, massive star and a compact object that can be either a young pulsar or a black hole. They emit radiation from radio up to tens of TeV and show flux variability along the whole electromagnetic spectrum. For three of the four detected gamma-ray binaries, the nature of the compact object is unknown. In this thesis we present a study of gamma-ray binaries through three approaches that involve the simultaneous study of these sources in X-rays and very high energy (VHE) gamma-rays.
We present the discovery of correlated X-ray and VHE gamma-ray emission from LS I +61 303. The correlations indicates that the emission from these two bands could be originated in the same parent particle population, and we explore this idea through the calculation of a radiative model. This model allows us to significantly constrain the physical properties of the non-thermal emitter in LS I +61 303.
For those systems where the compact object is a young pulsar, the interaction between the stellar and pulsar winds will give rise to strong shocks. The shocked pulsar wind is the candidate location for non-thermal emission from these systems. The shocked stellar wind should give rise to a thermal X-ray spectrum, but no such features have been detected in the X-ray spectrum of gamma-ray binaries. We present a model of the thermal emission of the shocked stellar wind and use it to constrain the pulsar properties. We have applied this method to two X-ray observations of LS 5039 and have successfully constrained the pulsar spin-down luminosity.
Finally, we present a search for VHE emission from Scorpius X-1 through a simultaneous X-ray and VHE gamma-ray campaign. The X-ray observations allowed us to select black-hole states where non-thermal X-ray emission has been detected. We did not find significant VHE emission in any of the black hole states, but the upper limits derived will prove useful in future modelling of the non-thermal emitter in the source.Les binàries de raigs gamma són sistemes binaries formats per una estrella jove i massiva i un objecte compacte, que pot ser un púlsar jove o un forat negre, que emeten radiació fins a desenes de TeV i mostren variabilitat orbital en totes les bandes d'emissió, des de radio fins a raigs gamma. En el cas de tres de les quatre binàries de raigs gamma detectades avui dia, se'n desconeix la natura de l'objecte compacte. En aquesta tesi presentem un estudi de les binàries de raigs gamma mitjançant tres treballs complementaris que involucren l'estudi simultani d'aquestes fonts en raigs X i raigs gamma de molt alta energia. En primer lloc presentem el descobriment d'emissió en raigs X i raigs gamma de molt alta energia correlades en el temps al sistema LS I +61 303. Aquesta correlació ens indica que l'emissió en les dues bandes pot provenir d'una única població d'electrons, i ho confirmem mitjançant la realització d'un model teòric de radiació que ens permet restringir significativament les propietats físiques de l'emissor no tèrmic de la font. En cas que la font energètica dels sistemes sigui un púlsar, la interacció entre els vents de l'estrella i el púlsar dona lloc a una regió d'interacció on el vent xocat del púlsar accelera partícules i emet des de radio fins a raigs gamma. A l'espectre de raigs X, però, no es detecta l'emissió tèrmica del vent xocat de l'estrella, que s'escalfa fins a desenes de milers de graus. Això ens ha permès estudiar la forma de la regió d'interacció, determinada principalment per la potència del púlsar, i fer un càlcul teòric de l'emissió en raigs X tèrmics. Hem aplicat aquest model al sistema LS 5039 i hem pogut determinar la potència del púlsar, fet important per a la modelització de l'emissió no tèrmica de la font. Finalment, presentem la cerca d'emissió de raigs gamma provinent de sistemes binaris fins ara no detectats. Una campanya simultània en raigs X i raigs gamma ens va permetre seleccionar les dades de molt alta energia del microquàsar Sco X-1 en funció de l'estat d'acreció sobre l'objecte compacte. Tot i no detectar la font en raigs gamma, els límits superiors obtinguts permeten restringir les propietats físiques de Sco X-1 rellevants per a l'emissió en molt alta energia.
31
Locklear, Jay Edward. "Secondary ion emission under keV carbon cluster bombardment." Diss., Texas A&M University, 2006. http://hdl.handle.net/1969.1/4273.
Full textAbstract:
Secondary ion mass spectrometry (SIMS) is a surface analysis technique capable of providing isotopic and molecular information. SIMS uses keV projectiles to impinge upon a sample resulting in secondary ion emission from nanometric dimensions. It is well documented that secondary ion emission is enhanced using cluster projectiles compared to atomic projectiles. Previous studies of enhanced secondary ion yields with cluster projectiles have led to the present study dealing with the scope of C60 as a projectile for SIMS. The secondary ion yields (i.e., the number of secondary ions detected per projectile impact) from impacts of 10-26 keV C24H12+, C60+, gramicidin S+ and C60F40+ projectiles were examined to compare the effectiveness of the projectiles. The [M-H]- secondary ion yields from several organic samples varied inversely with the molecular weight. Multiple ion emission decreases monotonically as a function of the number of secondary ions emitted per impact and varies with impact energy such that higher energies produce more multiple ion emission. The emission of CN- from biological samples as a function of carbon-based projectile characteristics was examined to explore the possibility of using CN- as a molecular identifier. CN- emission was found to be the product of both direct and recombination/rearrangement emission. Re-emitted projectile atoms in the form F- were found under C60F40+ bombardment. Two forms of re-emitted F- were found: One form in which F atoms retained a portion of the initial kinetic energy, and a second in which the F atoms deposited most of the initial kinetic energy into the surface before being ejected. The [M-H]- secondary ion yield of gramicidin S was increased ~ 15 times by embedding the analyte in a matrix of sinapic acid. These results show the optimum carbon based projectile for a given sample is dependent upon the signal to be monitored from the surface. The results also show CN- has potential as a molecular identifier. Additionally, the detection of re-emitted F- confirms prior predictions of re-emitted projectile atoms.
32
Williams, Scott Charles. "Absolute bremsstrahlung yields 53 keV electrons on gold /." Fort Worth, Tex. : Texas Christian University, 2007. http://etd.tcu.edu/etdfiles/available/etd-07022007-104158/unrestricted/williams.pdf.
Full text
33
SASANK, HYDERKHAN. "Performance analysis of TCP in KVM virtualized environment." Thesis, Blekinge Tekniska Högskola, Institutionen för kommunikationssystem, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-10793.
Full textAbstract:
The requirement of high quality services is increasing day by day. So, in order to meet up with this requirement new technologies are being developed one of them being virtualization. The main agenda of introducing virtualization is that though virtualization needs more powerful devices to run the hypervisor, the technique also helps to increase consolidation which makes efficient use of resources like increase in the CPU utilization. The virtualization technique helps us to run more VM’s (Virtual Machine) on the same platform i.e. on the same hypervisor. In virtualization as number of VM’s share the CPU will there be any effect on the performance of TCP with the performance influencing factors of virtualization. While TCP being the most widely used protocol and most reliable protocol can performance of TCP vary if different TCP congestion control mechanism are used in the virtualized environment are the main aims of this research. In this study, we investigate the performance influencing factor of TCP in the virtualized environment and whether those influencing factors have any role to play with the performance of the TCP. Also which TCP congestion control mechanism is best suitable in order to download files when virtualization is used will be investigated by setting up a client-server test bed. The different TCP congestion control mechanism which have been used are CUBIC, BIC, Highspeed, Vegas, Veno, Yeah, Westwood, LP, Scalable, Reno, Hybla. Total download time has been compared in order to know which congestion control algorithm performs better in the virtualized environment. The method that has been used to carry out the research is by experimentation. That is by changing the RAM sizes and CPU cores which are the performance influencing factors in virtualization and then analyzing the total download time while downloading a file by changing the TCP congestion control mechanisms by running a single guest VM. Apart from changing only congestion control mechanisms the other network parameters which effect the performance of the TCP such as Delay have been injected while downloading the file, to match up with the real time scenarios. Results collected include average download time of a file by changing the different memory sizes and different CPU cores. Average Download time for different TCP congestion controls mechanisms with inclusion of the parameter that effects the total download time such as Delay. From the results we got we can see that there is a slight influence on the performance of TCP by the performance influencing factors memory sizes and CPU cores allotted to the VM in the KVM virtualized environment and of all the TCP congestion control algorithms having TCP – BIC and TCP- YEAH performs the best in the KVM virtualized environment. The performance of TCP – LP is the least in the KVM virtualized environment.
34
Papakosta, Marianthi. "Structural and functional analysis of KVI K+ channels." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289870.
Full text
35
Geyikli, Turabi. "Finite element studies of the modified KdV equation." Thesis, Bangor University, 1994. https://research.bangor.ac.uk/portal/en/theses/finite-element-studies-of-the-modified-kdv-equation(3b972b37-ca65-466f-ad66-d3d313f76ec1).html.
Full textAbstract:
The main aim of this study is the construction of new efficient and accurate numerical algorithms based on the B-spline finite element method, for solution of the Korteweg-de Vries (KdV) and Modified Korteweg-de Vries (MKdV) equations. In the following chapters; the theoretical background to the KdV and MKdV equations is discussed, and existing numerical methods are described. Numerical solutions to the KdV and MKdV equations are obtained using the Galerkin and modified Petrov-Galerkin method with quadratic B-spline finite elements over which the non-linear term is locally linearised. The numerical algorithms have been validated by studying the motion, interaction and development of solitons. We have demonstrated that these algorithms can faithfully represent the amplitude of a single soliton over many time steps and the interaction of two solitons. A new numerical solution for the MKdV - equation is obtained using a "lumped" Galerkin method with quadratic 13- spline finite elements. The motion, interaction and generation of solitary waves are studied using the method. An unconditionally stable numerical algorithm is implemented for the solution of the MKdV equation using a collocation method with quartic 13- spline finite elements. The algorithm is validated through a single soliton simulation. In further numerical experiments forced boundary conditions u= Uo are applied at the end x=0 and the generated states of solitary waves are studied. The solitary wave states generated by applying a positive impulse followed immediately by an equal negative impulse is dependent on the period of forcing. The solitary waves generated by these various forcing functions possess many of the attributes of free solitons.
36
Oladipo, Adewale. "Désorption stimulée induite par des agrégats d'hydrogène (E ≤ 120 keV-u) et des ions lourds (E ≤ 400 keV-u) : applications analytiques." Lyon 1, 1988. http://www.theses.fr/1988LYO10032.
Full text
37
Pasumarthy, Sarat Chandra. "Live Migration of Virtual Machines in the Cloud : An Investigation by Measurements." Thesis, Blekinge Tekniska Högskola, Institutionen för kommunikationssystem, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-10770.
Full textAbstract:
Cloud computing has grown in prevalence from recent years due to its concept of computing as a service, thereby, allowing users to offload the infrastructure management costs and tasks to a cloud provider. Cloud providers leverage server virtualization technology for efficient resource utilization, faster provisioning times, reduced energy consumption, etc. Cloud computing inherits a key feature of server virtualization which is the live migration of virtual machines (VMs). This technique allows transferring of a VM from one host to another with minimal service interruption. However, live migration is a complex process and with a cloud management software used by cloud providers for management, there could be a significant influence on the migration process. This thesis work aims to investigate the complex process of live migration performed by the hypervisor as well as the additional steps involved when a cloud management software or platform is present and form a timeline of these collection of steps or phases. The work also aims to investigate the performance of these phases, in terms of time, when migrating VMs with different sizes and workloads. For this thesis, the Kernel-based Virtual Machine (KVM) hypervisor and the OpenStack cloud software have been considered. The methodology employed is experimental and quantitative. The essence of this work is investigation by network passive measurements. To elaborate, this thesis work performs migrations on physical test-beds and uses measurements to investigate and evaluate the migration process performed by the KVM hypervisor as well as the OpenStack platform deployed on KVM hypervisors. Experiments are designed and conducted based on the objectives to be met. The results of the work primarily include the timeline of the migration phases of both the KVM hypervisor and the OpenStack platform. Results also include the time taken by each migration phase as well as the total migration time and the VM downtime. The results indicate that the total migration time, downtime and few of the phases increase with increase in CPU load and VM size. However, some of the phases do not portray any such trend. It has also been observed that the transfer stage alone does not contribute and influence the total time but every phase of the process has significant influence on the migration process. The conclusions from this work is that although a cloud management software aids in managing the infrastructure, it has notable impact on the migration process carried out by the hypervisor. Moreover, the migration phases and their proportions not only depend on the VM but on the physical environment as well. This thesis work focuses solely on the time factor of each phase. Further evaluation of each phase with respect to its resource utilization can provide better insight into probable optimization opportunities.
38
Harshini, Nekkanti. "Measuring And Modeling Of Open vSwitch Performance : Implementation in Docker." Thesis, Blekinge Tekniska Högskola, Institutionen för kommunikationssystem, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-13479.
Full textAbstract:
Network virtualization has become an important aspect of the Telecom industry. The need forefficient, scalable and reliable virtualized network functions is paramount to modern networking.Open vSwitch is such virtual switch that attempts to extend the usage of virtual switches to industrygrade performance levels on heterogeneous platforms.The aim of the thesis is to give an insight into the working of Open vSwitch. To evaluate theperformance of Open vSwitch in various virtualization scenarios such as KVM (second companionthesis)[1] and Docker. To investigate different scheduling techniques offered by the Open vSwitchsoftware and supported by the Linux kernel such as FIFO, SFQ, CODEL, FQCODEL, HTB andHFSC. To differentiate the performance of Open vSwitch in these scenarios and scheduling capacitiesand determine the best scenario for optimum performance.The methodology of the thesis involved a physical model of the system used for real-timeexperimentation as well as quantitative analysis. Quantitative analysis of obtained results paved theway for unbiased conclusions. Experimental analysis was required to measure metrics such asthroughput, latency and jitter in order to grade the performance of Open vSwitch in the particularvirtualization scenario.The results of the thesis must be considered in context with a second companion thesis[1]. Both thethesis aim at measuring the performance of Open v-Switch but the virtualization scenarios (Dockerand KVM) which are chosen are different, However, this thesis outline the performance of Open vSwitch and linux bridge in docker scenario. Various scheduling techniques were measured fornetwork performance metrics across both Docker and KVM (second companion thesis) and it wasobserved that Docker performed better in terms of throughput, latency and jitter. In Docker scenarioamongst the scheduling algorithms measured, it has almost same throughput in all schedulingalgorithms and latency shows slight variation and FIFO has least latency, as it is a simplest algorithmand consists of default qdisk. Finally jitter also shows variation on all scheduling algorithms.The conclusion of the thesis is that the virtualization layer on which Open vSwitch operates is one ofthe main factors in determining the switching performance. The KVM scenario and Docker scenarioeach have different virtualization techniques that incur different overheads that in turn lead to differentmeasurements. This difference occurs in different packet scheduling techniques. Docker performsbetter than KVM for both bridges. In the Docker scenario Linux bridge performs better than that ofOpen vSwitch, throughput is almost constant and FIFO has a least latency amongst all schedulingalgorithms and jitter shows more variation in all scheduling algorithms.
39
Pothuraju, Rohit. "Measuring and Modeling of Open vSwitch Performance : Implementation in KVM environment." Thesis, Blekinge Tekniska Högskola, Institutionen för kommunikationssystem, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-13519.
Full textAbstract:
Network virtualization has become an important aspect of the Telecom industry. The need for efficient, scalable and reliable virtualized network functions is paramount to modern networking. Open vSwitch is a virtual switch that attempts to extend the usage of virtual switches to industry grade performance levels on heterogeneous platforms.The aim of the thesis is to give an insight into the working of Open vSwitch. To evaluate the performance of Open vSwitch in various virtualization scenarios such as KVM and Docker (from second companion thesis)[1]. To investigate different scheduling techniques offered by the Open vSwitch software and supported by the Linux kernel such as FIFO, SFQ, CODEL, FQCODEL, HTB and HFSC. To differentiate the performance of Open vSwitch in these scenarios and scheduling capacities and determine the best scenario for optimum performance.The methodology of the thesis involved a physical model of the system used for real-time experimentation as well as quantitative analysis. Quantitative analysis of obtained results paved the way for unbiased conclusions. Experimental analysis was required to measure metrics such as throughput, latency and jitter in order to grade the performance of Open vSwitch in the particular virtualization scenario.The result of this thesis must be considered in context with a second companion thesis[1]. Both the theses aim at measuring and modeling performance of Open vSwitch in NFV. However, the results of this thesis outline the performance of Open vSwitch and Linux bridge in KVM virtualization scenario. Various scheduling techniques were measured for network performance metrics and it was observed that Docker performed better in terms of throughput, latency and jitter. In the KVM scenario, from the throughput test it was observed that all algorithms perform similarly in terms of throughput, for both Open vSwitch and Linux bridges. In the round trip latency tests, it was seen that FIFO has the least round trip latency, CODEL and FQCODEL had the highest latencies. HTB and HFSC perform similarly in the latency test. In the jitter tests, it was seen that HTB and HFSC had highest average jitter measurements in UDP Stream test. CODEL and FQCODEL had the least jitter results for both Open vSwitch and Linux bridges.The conclusion of the thesis is that the virtualization layer on which Open vSwitch operates is one of the main factors in determining the switching performance. Docker performs better than KVM for both bridges. In the KVM scenario, irrespective of the scheduling algorithm considered, Open vSwitch performed better than Linux bridge. HTB had highest throughput and FIFO had least round trip latency. CODEL and FQCODEL are efficient scheduling algorithms with low jitter measurements.
40
Paula, Daniela Rezende de. "Análise da inadimplência no mercado de financiamento de automóveis no Brasil: uma proposta de adaptação do modelo KMV." Universidade Presbiteriana Mackenzie, 2010. http://tede.mackenzie.br/jspui/handle/tede/984.
Full textAbstract:
Made available in DSpace on 2016-03-15T19:33:04Z (GMT). No. of bitstreams: 1
Daniela Rezende de Paula.pdf: 383337 bytes, checksum: 2c7c9d004a174c0b9a286928d37a9eef (MD5)
Previous issue date: 2010-03-01Fundo Mackenzie de Pesquisa
Sales of new cars in Brazil have increased significantly in the last decade, with average growth of 10% per year. Government incentives, such as tax reduction, were used as a forcing agent for the segment during the crisis period between 2008 and 2009. With the continuation of strong market, funding also increase . The objective of this research is to test, based on a study Securato (2003), who adapted the KMV model to study the probability of default for private companies, which is the default risk associated with the financing of vehicles, using as variables the relationship between debt and payment to the contractor for the good and the devaluation of the prices of passenger cars and light commercial market. The adaptation of the KMV model, however, showed no predictive ability for the market of auto finance.
As vendas de veículos novos no Brasil vêm aumentando significativamente na última década, com crescimento médio de 10% ao ano. Incentivos governamentais, como a redução da carga tributária, foram usados como agentes impulsionares para o segmento durante o período de crise entre 2008 e 2009. Com a manutenção do mercado aquecido, os financiamentos também cresceram. O objetivo desta pesquisa é testar, baseando-se em um estudo de Securato (2003), que adaptou o modelo KMV para estudar a probabilidade de inadimplência em empresas de capital fechado, qual é o risco de inadimplência associado ao financiamento de veículos, usando como variáveis a relação entre dívida contratada e pagamento à vista do bem e a desvalorização dos preços dos veículos de passeio e comerciais leves no mercado. A adaptação do modelo KMV, entretanto, não mostrou capacidade preditiva para o mercado de financiamento de automóveis.
41
Van, Graan J. S. "Procurement of grapes for KWV from South African suppliers." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/6440.
Full text
42
Chavez, Fuentes Jorge Richard. "Teoria quase-linear de Kato e a KdV transicional." reponame:Repositório Institucional da UFSC, 1998. http://repositorio.ufsc.br/xmlui/handle/123456789/77695.
Full textAbstract:
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias Fisicas e MatematicasMade available in DSpace on 2012-10-17T06:39:50Z (GMT). No. of bitstreams: 0Bitstream added on 2016-01-09T00:26:54Z : No. of bitstreams: 1 110182.pdf: 1957841 bytes, checksum: 9673937d339074a6f9aec61c16d5f03f (MD5)
Neste trabalho desenvolvemos a teoria linear e quase-linear de T. Kato e fazemos uma aplicação à equação de Korteweg-de Vries transicional (t-KdV), mostramos que o problema de Cauchy associado a esta equação tem solução única local nos espaços de Sobolev usuais.
43
Outadi, Siavash, and Jana Trchalikova. "Performance comparison of KVM and XEN for telecommunication services." Thesis, Blekinge Tekniska Högskola, Institutionen för datalogi och datorsystemteknik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-2552.
Full textAbstract:
High stability of telecommunication services has a positive e ect on customer satisfaction and thus helps to maintain competitiveness of the product in telecommunication market. Since live migration provides a minimal down- time of virtual machines, it is deployed by telecommunication companies to ensure high availability of services and to prevent service interruptions. The main objective of this research is to assess the performance of various hypervisors in terms of live migration and determine which of them best meets the criteria given by a telecommunication company. Response time and CPU utilization of telecommunication services are measured in non- virtualized and virtualized environments to better understand the impacts of virtualization on the services. Two hypervisors, i.e. KVM and XEN, are used to grasp their characteristic behaviour of handling the services. Furthermore, performance of live migration is assessed for both hypervisors using miscellaneous test cases to identify which one has the best overall performance in terms of downtime and total migration time.
44
Lee, Chun-Te. "Multi-soliton solution of the two-mode KdV equation." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531973.
Full text
45
Aboukhder, Omar M. "Performance enhancement of the Surrey 400 keV ion implanter." Thesis, University of Surrey, 1990. http://epubs.surrey.ac.uk/843011/.
Full textAbstract:
Performance enhancement of the Surrey 400 keV ion implanter has been successfully implemented by upgrading the ion optics and installing a computerised telemetry system. Ion optics improvements include redesigning the mass analyser system and designing and installing a double electrostatic quadrupole lens. Telemetry enhancements entailed designing and installing an "intelligent" multiplexer system within the high voltage terminal and connecting this system to computers at earth potential using only two (Down- and Up-link) fibre optic lines. This new system solved the problem of frequent failures caused by current discharges. Other telemetry improvements included: upgrading all data acquisition and conversion head units especially those monitoring the critical parameters; standardising the design of voltage-to-frequency (V/F) head units and installing these as boxed modules; and, increasing the number of telemetry channels (from 15 to 22) to monitor the (original 15 plus the seven newly developed) sub-systems within the high voltage terminal. Upgrading of the machine optics and electronics not only remedied several of the shortcomings of the original machine, but also worked to produce an equipment with better operational characteristics. Currently, the implanter is capable of resolving ion species with masses up to 241 amu, which enables selected isotopes from across the periodic table to be ion implanted. Ray tracing simulations show that the machine now has a much-improved beam transport efficiency with a smaller and more symmetric beam spot at the target. Experiments using 100 keV Ar+ showed that the beam spot is 5mm x 3mm as against 35mm x 20mm in the old system. At the same time, the implanter has a reliable telemetry system which efficiently links together all of its sub-systems within the high voltage terminal. Performance measurements showed that there has been a significant improvement in channel accuracies (from 1% to at least 0.3%) as well as an increase in its measurement speed, being at least five times faster. The best indicator of implanter reliability, however, is that since the commissioning of both optics and electronics improvements in 1988, there has been no reported telemetry breakdown. This not only provides substantial savings in machine maintenance and repairs, but, also increased the productivity of the implanter. These improvements in hardware have made the machine more amenable to and worthy of computer control. To ensure tighter control and to enhance the reliability of the implanter, a distributed computer control system for the automatic control of the whole implanter has also been designed. Within this control configuration, three types of applications software have been developed, tested and subsequently implemented to control the Beam Generation and Analysis sub-systems. These Assembly code programmes provide the operator with real-time information which enable him to conduct fault diagnosis, parameter calibration, and, on a day to day basis, perform the setting up and control of the implanter. In the future, the software can be expanded and integrated into the final algorithm needed to implement the closed-loop computer control of the implanter. Full automation will further enhance the implanter's performance and reliability. In summary, major improvements have been made to the 400 kV high current implanter at the University of Surrey. This has greatly enhanced the purity of the beam at the target and the reliability of the machine. As a result, this project serves to enhance the quality of research in the field of ion implantation technology within the Department. It also contributes to ongoing research in the development of implanter telemetry and control systems.
46
Zápařková, Kateřina. "Analýza chovu plemene Shagya-arab v České republice." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-250188.
Full textAbstract:
The aim of this thesis was the first part of their work to process data on the number of foals born, import and export, trends in breeds of horses Shagya Arabian (Sh-a) and data horse's active Sh-a in the Czech Republic for the year 2014. The data were processed in Microsoft Office Excel 2007 and have created graphs. However, the number of foals born, it was found that most of them were born in 2009 and 2002. Import greatly outweighed exports, but in recent years also began to flourish and export. States Shagya-Arabians in the Czech Republic since 1994, continues to grow. In 2014, the Czech Republic 283 broodmares, 176 geldings, 142 mares, 133 stallions and 31 sire. In the second part of their work was the aim statistically evaluate data mares entered in the Stud book. This program was used Unistat 5.5. First, the statistical effect was studied by GLM and positive results have been used multiple comparisons by Tukey-B. It was found that on the basic colour has a highly significant influence line and family. Were examined influences on 4 basic body measurements (withers high tape, withers high rod, chest circumference, circumference of the cannon bone), where it was found that withers high tape, withers high rod, and chest circumference have a statistically significant effect of a family and line. The overall gain points is statistically highly significant influence lines and the number of ox 4th generation.
47
Vardanyan, Vitya Andranic [Verfasser]. "Structural requirements and role of oxidoreductase features for Kvβ-mediated [Kv-beta-mediated] potassium channel inactivation / vorgelegt von Vitya Andranic Vardanyan." 2004. http://d-nb.info/972150544/34.
Full text
48
TangYing-Jie and 唐英傑. "A Programmable KTV System." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/55712244877144171724.
Full textAbstract:
碩士崑山科技大學
電子工程研究所
93
Since the appearance of Karaoke television (KTV) it is even more relaxing and pleasing for people -with the help of a TV screen and a stereo- to start singing songs. That is why KTV became the splendid, cannot-take-the-hands-off product in the life of modern people. This thesis puts forward an analysis of constructing and designing a programmable KTV system , that enables users to compile KTV by themselves; creating a unique personal KTV. In order to proof and verify the feasibility of the above mentioned proposition, this thesis takes the TM5320DSC25 by Texas Instrument Inc. as a hardware platform, researches and shows how to create KTV machines, group MP3s, JPEG and other multimedia decoding programs to obtain integrated multimedia broadcasting functions. Furthermore a USB mass storage transmission standard is written, that enables this system to carry out transfers between personal computers. In order to let Chinese conveniently use this system, the author creates this system in Chinese, besides it can be used as a linked up user’s interface, that is capable of displaying KTV subtitles. Concerning the integrated multimedia capabilities, this thesis defines KTV subtitles and its speed of being displayed according to the music data files. Further so called “KTV defining files” define all needed music, background and music data files, so that subtitles, background and music, these three different kinds of media, can be run simultaneously. Without any editing software the user is enabled to create a personalized KTV all by himself.
49
Chuang, Kangway V. "A Total Synthesis of (+)-Ryanodol." Thesis, 2016. https://thesis.library.caltech.edu/9865/1/KVC-Thesis.pdf.
Full textAbstract:
Highly oxygenated, architecturally complex terpenoids constitute a biologically important class of natural products, yet their development into medicinally relevant analogs and effective biological probes are obstructed by their synthetic accessibility. Ryanodine is a unique diterpenoid that exhibits high affinity to a class of intracellular calcium ion channels bearing its name: ryanodine receptors. Structure-activity relationship studies have demonstrated how peripheral structural modifications affect binding affinity and selectivity among receptor isoforms, but to date have been limited to analogs prepared via chemical derivatization of natural material due to the intractability of total chemical synthesis.
This thesis details synthetic efforts culminating in a total synthesis of ryanodol that proceeds in only 15-steps from commercially available (–)-pulegone. Early stage oxygen atom incorporation is strategically implemented to facilitate key, stereoselective carbon-carbon bond formation. In particular, a rhodium-catalyzed, intramolecular Pauson–Khand reaction is utilized to rapidly assemble the tetracyclic ABCD-ring system that constitutes the anhydroryanodol core. A novel, selenium-dioxide mediated oxidation to install three oxidation states and three oxygen atoms was discovered, enabling the rapid oxidative functionalization of the ryanodol A-ring. The modular route described herein allows for the preparation of synthetic structural analogs not readily accessible via chemical degradation, and is anticipated to enable rapid construction and evaluation of biologically active ryanodine analogs.
50
Chen, Shin-hong, and 陳信宏. "The Fault Tolerant KVM implementation." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/4bp5q3.
Full textAbstract:
碩士國立中央大學
軟體工程研究所
102
With the extensive use of virtualization technology, a single physical machine is no longer just set up as a single server. Instead, single physical machine is virtualized into several virtual machines to host multiple servers. So the manufacturers of server want to install virtualization solution on their products as a turnkey solution to increase the added value of products. However, virtualization will derive a single point of failure problem that is a physical machine failure affects all virtual machines running on it. This decreases the availability of virtualization. It can improve lots of value for the server product as long as the manufacturers of server use high-availability virtual machine as their turnkey solutions. So we can see the importance of high-availability virtual machine. Currently there is only VMware which has commercial high-availability virtual machine product. The manufacturers of server need to pay expensive royalties to VMware to get authorization. Here we implement a highly available virtual machines in KVM virtual machine open source project that achieves comparable performance of VMware, so the manufacturers of server looking for these high-availability virtual machine turnkey solution has a choice of a low-cost highly available virtual machine solution.