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Journal articles on the topic 'L^infinity Data'

Author: Grafiati

Published: 9 March 2023

Last updated: 10 March 2023

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1

Bamieh, B., M. A. Dahleh, and J. B. Pearson. "Minimization of the L/sup infinity /-induced norm for sampled-data systems." IEEE Transactions on Automatic Control 38, no. 5 (1993): 23. http://dx.doi.org/10.1109/9.277236.

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Sychev, M. A. "Characterization of homogeneous scalar variational problems solvable for all boundary data." Proceedings of the Royal Society of Edinburgh: Section A Mathematics 130, no. 3 (2000): 611–31. http://dx.doi.org/10.1017/s0308210500000330.

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It is known that the condition ‘either ∂L (F) ≠ Ø or there exist υ1,…,υq ∈ Rnsuch thatF ∈ int co {υ1,…,υq} characterizes solvability of the problem with f(·) = 〈F,·〉.We extend this result to the case of lower semicontinuous integrands L : Rn → R.We also show that validity of this condition for all F ∈ Rn is both a necessary and sufficient requirement for solvability of all minimization problems with sufficiently regular Ω and f. Moreover, the assumptions on Ω and f can be completely dropped if L has sufficiently fast growth at infinity.

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Karpińska, M., M. Wlazło, D. Ramjugernath, P. Naidoo, and U. Domańska. "Assessment of certain ionic liquids for separation of binary mixtures based on gamma infinity data measurements." RSC Advances 7, no. 12 (2017): 7092–107. http://dx.doi.org/10.1039/c6ra25208g.

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Limiting activity coefficients for 64 solutes in [BzMIM][NTf<sub>2</sub>] and [BzMIM][DCA], the gas–liquid partition coefficients, K<sub>L</sub>, thermodynamic functions and selectivity for hexane/hex-1-ene, cyclohexane/cyclohexene and ethylbenzene/styrene separation were presented.

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Gajic, Dejan, and Claude Warnick. "Quasinormal Modes in Extremal Reissner–Nordström Spacetimes." Communications in Mathematical Physics 385, no. 3 (2021): 1395–498. http://dx.doi.org/10.1007/s00220-021-04137-4.

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AbstractWe present a new framework for characterizing quasinormal modes (QNMs) or resonant states for the wave equation on asymptotically flat spacetimes, applied to the setting of extremal Reissner–Nordström black holes. We show that QNMs can be interpreted as honest eigenfunctions of generators of time translations acting on Hilbert spaces of initial data, corresponding to a suitable time slicing. The main difficulty that is present in the asymptotically flat setting, but is absent in the previously studied asymptotically de Sitter or anti de Sitter sub-extremal black hole spacetimes, is tha

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Arifin, Ajib Setyo, and Tomoaki Ohtsuki. "Capacity of Data Collection in Wireless Sensor Networks Based on Mutual Information and MMSE Estimation." ISRN Sensor Networks 2014 (February 17, 2014): 1–9. http://dx.doi.org/10.1155/2014/389451.

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We investigate the properties of data collection in wireless sensor networks, in terms of both capacity and power allocation strategy. We consider a scenario in which a number of sensors observe a target being estimated at fusion center (FC) using minimum mean-square error (MMSE) estimator. Based on the relationship between mutual information and MMSE (I-MMSE), the capacity of data collection in coherent and orthogonal multiple access channel (MAC) models is derived. Considering power constraint, the capacity is derived under two scenarios: equal power allocation and optimal power allocation o

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Jamali, A., and F. A. Castro. "TOPOLOGICAL 3D ELEVATION DATA INTERPOLATION OF ASTER GDEM BASED ON CONTINUOUS DEFORMATION." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-4/W10 (September 12, 2018): 71–77. http://dx.doi.org/10.5194/isprs-archives-xlii-4-w10-71-2018.

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<p><strong>Abstract.</strong> In Geographic Information Science, polynomial methods such as linear estimation and non-polynomial methods including Inverse Distance Weighting and Kriging have been used for elevation data interpolation. In this paper, 3D data interpolation using linear and non-linear homotopy continuation as well as advanced polynomial interpolation methods are researched. Continuous deformations that reconstruct straight lines or algebraic curves between any pair of 3D data are presented. The implemented topological mathematical algorithm for 3D elevation data

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LI, DONG, TONG LI, and KUN ZHAO. "ON A HYPERBOLIC–PARABOLIC SYSTEM MODELING CHEMOTAXIS." Mathematical Models and Methods in Applied Sciences 21, no. 08 (2011): 1631–50. http://dx.doi.org/10.1142/s0218202511005519.

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We investigate local/global existence, blowup criterion and long-time behavior of classical solutions for a hyperbolic–parabolic system derived from the Keller–Segel model describing chemotaxis. It is shown that local smooth solution blows up if and only if the accumulation of the L∞ norm of the solution reaches infinity within the lifespan. Our blowup criteria are consistent with the chemotaxis phenomenon that the movement of cells (bacteria) is driven by the gradient of the chemical concentration. Furthermore, we study the long-time dynamics when the initial data is sufficiently close to a c

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Chiarello, Felisia Angela, and Paola Goatin. "Global entropy weak solutions for general non-local traffic flow models with anisotropic kernel." ESAIM: Mathematical Modelling and Numerical Analysis 52, no. 1 (2018): 163–80. http://dx.doi.org/10.1051/m2an/2017066.

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We prove the well-posedness of entropy weak solutions for a class of scalar conservation laws with non-local flux arising in traffic modeling. We approximate the problem by a Lax-Friedrichs scheme and we provide L∞ and BV estimates for the sequence of approximate solutions. Stability with respect to the initial data is obtained from the entropy condition through the doubling of variable technique. The limit model as the kernel support tends to infinity is also studied.

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Hoang, Luan T., and Thinh T. Kieu. "Interior Estimates for Generalized Forchheimer Flows of Slightly Compressible Fluids." Advanced Nonlinear Studies 17, no. 4 (2017): 739–67. http://dx.doi.org/10.1515/ans-2016-6027.

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AbstractThe generalized Forchheimer flows are studied for slightly compressible fluids in porous media with time-dependent Dirichlet boundary data for the pressure. No restrictions are imposed on the degree of the Forchheimer polynomial. We derive, for all time, the interior {L^{\infty}}-estimates for the pressure, its gradient and time derivative, and the interior {L^{2}}-estimates for its Hessian. The De Giorgi and Ladyzhenskaya–Uraltseva iteration techniques are used taking into account the special structures of the equations for both pressure and its gradient. These are combined with the u

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Sulttan, Mohammed. "Impact of using Infinity-Norm with Initial Radius on Performance and Complexity of SD Algorithm in MIMO systems." INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY 15, no. 6 (2016): 6857–64. http://dx.doi.org/10.24297/ijct.v15i6.1614.

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Â In recent years, the iterative decoding techniques have played a role in improving the performance (e.g., bit error rate) and reducing the complexity of various digital communication systems. Techniques of Multiple-Input Multiple-Output (MIMO) are the main technology to enhance and achieve high-speed, high data rates, improved reliability and coverage in wireless communications. The modern wireless communications require a low complexity system for detection, since a high CPU processing involves more energy consumption and thus less flexibility in mobility terms. The sphere decoding (SD) tec

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Pfiffner, M., V. Gotta, E. Berger-Olah, M. Pfister, and P. Vonbach. "P78 Pharmacokinetics of intravenous and intranasal nalbuphine in infants." Archives of Disease in Childhood 104, no. 6 (2019): e49.2-e49. http://dx.doi.org/10.1136/archdischild-2019-esdppp.116.

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BackgroundNalbuphine is a mixed agonist-antagonist opioid analgesic agent frequently used in paediatrics, and licensed for parenteral use only. Intranasal delivery could be a safe, effective and non-invasive alternative, especially in infants in the acute setting. However, pharmacokinetic (PK) data for this route of administration is completely lacking. The aim of this study was to assess PK of nalbuphine in infants 1–3 months after single intravenous (0.05 mg/kg) and intranasal (0.1 mg/kg) application, respectively.MethodsWe conducted a prospective, single centre, open-label pharmacokinetic s

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Sychev, Mikhail A., Giulia Treu, and Giovanni Colombo. "Stable minimizers of functionals of the gradient." Proceedings of the Royal Society of Edinburgh: Section A Mathematics 150, no. 5 (2019): 2642–55. http://dx.doi.org/10.1017/prm.2019.38.

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AbstractLet Ω ⊂ ℝn be a bounded Lipschitz domain. Let $L: {\mathbb R}^n\rightarrow \bar {\mathbb R}= {\mathbb R}\cup \{+\infty \}$ be a continuous function with superlinear growth at infinity, and consider the functional $\mathcal {I}(u)=\int \nolimits _\Omega L(Du)$, u ∈ W1,1(Ω). We provide necessary and sufficient conditions on L under which, for all f ∈ W1,1(Ω) such that $\mathcal {I}(f) < +\infty $, the problem of minimizing $\mathcal {I}(u)$ with the boundary condition u|∂Ω = f has a solution which is stable, or – alternatively – is such that all of its solutions are stable. By stabili

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Tiganov, George, Magda-Ioana Nenciu, Cristian Sorin Danilov, and Victor Nicolae Nita. "Estimates of the Population Parameters and Exploitation Rate of Pontic Shad (Alosa Immaculata Bennett, 1835) in the Romanian Black Sea Coast." “Agriculture for Life, Life for Agriculture” Conference Proceedings 1, no. 1 (2018): 162–67. http://dx.doi.org/10.2478/alife-2018-0024.

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Abstract Sex ratio, morphometric characteristics, age and growth for Pontic shad from Romanian Black Sea Coast were examined. A total of 2.133 individuals were caught between March 2012 and September 2013. Female : male sex ratio was 0.62. According to the age reading, distribution varied form II to V year. The von Bertalanffy equation and growth performance index were determined by ESP software in Pontic shad. The asymptotic length (L∞ = L infinity) of Pontic shad generated by the ELEFAN I method, after introducing total length data for the two years of study, was 41.5. The natural mortality

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Wang, L. H., M. Schultz, S. Weller, M. L. Smiley, and M. R. Blum. "Pharmacokinetics and safety of multiple-dose valaciclovir in geriatric volunteers with and without concomitant diuretic therapy." Antimicrobial Agents and Chemotherapy 40, no. 1 (1996): 80–85. http://dx.doi.org/10.1128/aac.40.1.80.

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A randomized, double-blind study was conducted to evaluate the safety and pharmacokinetics of acyclovir following multiple-dose oral administration of valaciclovir (three times a day for 8 days) in geriatric volunteers (65 to 83 years of age). Pharmacokinetic evaluation was performed for three groups: normotensive subjects given 500-mg doses of valaciclovir (n = 11), normotensive subjects given, 1,000-mg doses of valaciclovir (n = 9), and thiazide diuretic-treated hypertensive subjects given 500-mg doses of valaciclovir (n = 9). Valaciclovir, the l-valyl ester of acylclovir, was rapidly absorb

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Elsheikh Abdelrahman, Abubaker, Fatima Abbas, and Selma Elsheikh Abdelrahman. "Crystallites Dimensions and Electrical Conductivity of Solid Carbon Pellets (SCPs) from Date Palm Leaves (Phoenix dactylifera L.)." Academic Journal of Research and Scientific Publishing 4, no. 45 (2023): 05–21. http://dx.doi.org/10.52132/ajrsp.en.2023.45.1.

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Solid carbon pellets (SCPs) were prepared from self-adhesive properties of date palm leaves (Phoenix dactylifera L.), primary pre-carbonized at low temperature, milled to fine grain, powdered, and pelletized as a grain pellet by applying of (5-21) metric tons of compression load, to carbonization at 1000 ºC. The SCPs produced were analyzed in terms of the volume shrinkage, carbon yield, crystallites dimensions and electrical conductivity of the solid carbon pellets as a function of compression load. The values of the electrical conductivity were further analyzed in terms of percolation theory

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Sawetri, Sevi, Subagdja Subagdja, and Dina Muthmainnah. "POPULATION DYNAMICS OF MALAYAN LEAF FISH (Pristolepisgrooti Blkr.) IN RANAU LAKE, SOUTH SUMATRA." Indonesian Fisheries Research Journal 24, no. 2 (2018): 125. http://dx.doi.org/10.15578/ifrj.24.2.2018.125-131.

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The Malayan leaf fish or locally named as kepor (Pristolepis grooti) is one of important biotic components in Ranau Lake ecosystems. This study aimed to estimate population dynamic and exploitation rate of kepor in Ranau Lake, South Sumatera. The population parameters are estimated based on length frequency data which were collected in March to October 2013. Growth parameters and fishing mortality rates were calculated using FiSAT software package. The results showed that kepor’s growth was negative allometric, which tended to gain length faster than weight. Kepor population was dominated (42%

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Davison, Andrew S., Brendan P. Norman, Hazel Sutherland, et al. "Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria." Metabolites 12, no. 6 (2022): 477. http://dx.doi.org/10.3390/metabo12060477.

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Background: Nitisinone-induced hypertyrosinaemia is well documented in Alkaptonuria (AKU), and there is uncertainty over whether it may contribute to a decline in cognitive function and/or mood by altering neurotransmitter metabolism. The aim of this work was to evaluate the impact of nitisinone on the cerebrospinal fluid (CSF) metabolome in a murine model of AKU, with a view to providing additional insight into metabolic changes that occur following treatment with nitisinone. Methods: 17 CSF samples were collected from BALB/c Hgd−/− mice (n = 8, treated with nitisinone—4 mg/L and n = 9, no tr

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Charão, Ruy Coimbra, Alessandra Piske, and Ryo Ikehata. "A dissipative logarithmic-Laplacian type of plate equation: Asymptotic profile and decay rates." Discrete & Continuous Dynamical Systems 42, no. 5 (2022): 2215. http://dx.doi.org/10.3934/dcds.2021189.

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<p style='text-indent:20px;'>We introduce a new model of the logarithmic type of wave like plate equation with a nonlocal logarithmic damping mechanism. We consider the Cauchy problem for this new model in <inline-formula><tex-math id="M1">\begin{document}$ {{\bf R}}^{n} $\end{document}</tex-math></inline-formula>, and study the asymptotic profile and optimal decay rates of solutions as <inline-formula><tex-math id="M2">\begin{document}$ t \to \infty $\end{document}</tex-math></inline-formula> in <inline-formula><tex-math id="M3"&g

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Madan, Mina, Tasnim Vira, Emmanouil Rampakakis, et al. "A Randomized Trial Assessing the Effectiveness of Ezetimibe in South Asian Canadians with Coronary Artery Disease or Diabetes: The INFINITY Study." Advances in Preventive Medicine 2012 (2012): 1–11. http://dx.doi.org/10.1155/2012/103728.

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Background. There is a paucity of data regarding the effectiveness and safety of lipid-lowering treatments among South-Asian patients.Methods. Sixty-four South-Asian Canadians with coronary artery disease or diabetes and persistent hypercholesterolemia on statin therapy, were randomized to ezetimibe 10 mg/day co-administered with statin therapy (EZE + Statin) or doubling their current statin dose (STAT2). Primary outcome was the proportion of patients achieving target LDL-C (<2.0 mmol/L) after 6 weeks. Secondary outcomes included the change in lipid profile and the incidence of treatment-em

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Dunbar, Joi, Jylle Nevejans, Charlotte McKee та ін. "Pharmacokinetics and Pharmacodynamics of IPI-145, a Potent Inhibitor of Phosphoinositide-3-Kinase-δ,γ, Following Single- and Multiple-Dose Administration in Healthy Subjects and Patients with Advanced Hematologic Malignancies". Blood 120, № 21 (2012): 4853. http://dx.doi.org/10.1182/blood.v120.21.4853.4853.

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Abstract Abstract 4853 Introduction: Phosphoinositide-3-kinases (PI3Ks) play pivotal roles in cell signaling and regulate a variety of cellular functions. PI3K-δ and PI3K-γ isoforms are necessary for adaptive and innate immunity and contribute to the development and maintenance of inflammatory and autoimmune diseases and hematologic malignancies. IPI-145 is a potent inhibitor of PI3K- δ,γ isoforms (Ki = 23 pM and 243 pM, respectively) in clinical development for patients with advanced hematologic malignancies and inflammatory/autoimmune disorders. The pharmacokinetics (PK) and pharmacodynamics

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Ben Abdallah, N., F. Méhats, and N. Vauchelet. "DIFFUSIVE TRANSPORT OF PARTIALLY QUANTIZED PARTICLES: EXISTENCE, UNIQUENESS AND LONG-TIME BEHAVIOUR." Proceedings of the Edinburgh Mathematical Society 49, no. 3 (2006): 513–49. http://dx.doi.org/10.1017/s0013091504000987.

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AbstractA self-consistent model for charged particles, accounting for quantum confinement, diffusive transport and electrostatic interaction is considered. The electrostatic potential is a solution of a three-dimensional Poisson equation with the particle density as the source term. This density is the product of a two-dimensional surface density and that of a one-dimensional mixed quantum state. The surface density is the solution of a drift–diffusion equation with an effective surface potential deduced from the fully three-dimensional one and which involves the diagonalization of a one-dimen

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Smith, E. B., F. M. Williams, and C. R. Fisher. "Effects of intrapopulation variability on von Bertalanffy growth parameter estimates from equal mark–recapture intervals." Canadian Journal of Fisheries and Aquatic Sciences 54, no. 9 (1997): 2025–32. http://dx.doi.org/10.1139/f97-110.

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The effects of intrapopulation variability on the parameter estimates of the von Bertalanffy growth equation have received discussion in the literature. Here we evaluated the effects of intrapopulation variability, using computer simulations, on four commonly used methods for estimating the von Bertalanffy growth parameters: the Ford-Walford plot, Ricker's method, Bayley's method, and Fabens' method. Intrapopulation variability in growth rates (k) and maximum sizes ( L infinity ) plus initial size distributions and measurement error, were tested for their effects on the accuracy of the paramet

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DIAS, KEALEY. "Enumerating combinatorial classes of the complex polynomial vector fields in ℂ". Ergodic Theory and Dynamical Systems 33, № 2 (2012): 416–40. http://dx.doi.org/10.1017/s0143385711000952.

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AbstractIn order to understand the parameter space Ξd of monic and centered complex polynomial vector fields in ℂ of degree d, decomposed by the combinatorial classes of the vector fields, it is interesting to know the number of loci in parameter space consisting of vector fields with the same combinatorial data (corresponding to topological classification with fixed separatrices at infinity). This paper answers questions posed by Adam L. Epstein and Tan Lei about the total number of combinatorial classes and the number of combinatorial classes corresponding to loci of a specific (real) dimens

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Stewart, C. F., S. D. Baker, R. L. Heideman, D. Jones, W. R. Crom, and C. B. Pratt. "Clinical pharmacodynamics of continuous infusion topotecan in children: systemic exposure predicts hematologic toxicity." Journal of Clinical Oncology 12, no. 9 (1994): 1946–54. http://dx.doi.org/10.1200/jco.1994.12.9.1946.

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PURPOSE Topotecan pharmacokinetics and pharmacodynamics were studied following a 72-hour continuous infusion in 20 children with cancer (median age, 8 years; range, 3.5 to 18). METHODS Serial plasma and urine samples were collected during the infusion and for up to 6 hours following the end of infusion. Topotecan (lactone) and total (lactone plus hydroxy acid) concentrations were determined by a sensitive and specific high-performance liquid chromatography (HPLC) assay with fluorescence detection. Using maximum a posteriori-Bayesian modeling, lactone and total plasma concentrations were descri

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Gonçalves, Sílvia. "THE MOVING BLOCKS BOOTSTRAP FOR PANEL LINEAR REGRESSION MODELS WITH INDIVIDUAL FIXED EFFECTS." Econometric Theory 27, no. 5 (2011): 1048–82. http://dx.doi.org/10.1017/s0266466610000630.

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In this paper we propose a bootstrap method for panel data linear regression models with individual fixed effects. The method consists of applying the standard moving blocks bootstrap of Künsch (1989, Annals of Statistics 17, 1217–1241) and Liu and Singh (1992, in R. LePage & L. Billiard (eds.), Exploring the Limits of the Bootstrap) to the vector containing all the individual observations at each point in time. We show that this bootstrap is robust to serial and cross-sectional dependence of unknown form under the assumption that n (the cross-sectional dimension) is an arbitrary nondecrea

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Ashton, A. C. L., and A. S. Fokas. "A novel method of solution for the fluid-loaded plate." Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 465, no. 2112 (2009): 3667–85. http://dx.doi.org/10.1098/rspa.2009.0170.

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We study the equations governing a fluid-loaded plate. We first reformulate these equations as a system of two equations, one of which is an explicit non-local equation for the wave height and the velocity potential on the free surface. We then concentrate on the linearized equations and show that the problems formulated either on the full or the half-line can be solved by employing the unified approach to boundary value problems introduced by one of the authors in the late 1990s. The problem on the full line was analysed by Crighton & Oswell (Crighton & Oswell 1991 Phil. Trans. R. Soc

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Kaul, S., L. N. Igwemezie, D. J. Stewart, et al. "Pharmacokinetics and bioequivalence of etoposide following intravenous administration of etoposide phosphate and etoposide in patients with solid tumors." Journal of Clinical Oncology 13, no. 11 (1995): 2835–41. http://dx.doi.org/10.1200/jco.1995.13.11.2835.

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PURPOSE To assess the pharmacokinetics and bioequivalence of etoposide following intravenous (i.v.) administration of etoposide phosphate (Etopophos; Bristol-Myers Squibb, Princeton, NJ), a prodrug of etoposide, and VePesid (Bristol-Myers Squibb). PATIENTS AND METHODS Forty-nine solid tumor patients were randomized to receive Etopophos or VePesid on day 1 of a day-1,3,5 schedule of treatment. The alternate drug was given on day 3 and repeated on day 5. The dose, 150 mg/m2 of etoposide equivalent, was administered by constant rate infusion over 3.5 hours. The plasma concentrations of etoposide

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Fu, Yingjia, and Ruth J. Williams. "Stability of a Subcritical Fluid Model for Fair Bandwidth Sharing with General File Size Distributions." Stochastic Systems 10, no. 3 (2020): 251–73. http://dx.doi.org/10.1287/stsy.2019.0058.

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This work concerns the asymptotic behavior of solutions to a (strictly) subcritical fluid model for a data communication network, where file sizes are generally distributed and the network operates under a fair bandwidth-sharing policy. Here we consider fair bandwidth-sharing policies that are a slight generalization of the [Formula: see text]-fair policies introduced by Mo and Walrand [Mo J, Walrand J (2000) Fair end-to-end window-based congestion control. IEEE/ACM Trans. Networks 8(5):556–567.]. Since the year 2000, it has been a standing problem to prove stability of the data communications

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Aida, Siti Nurul, and Agus Djoko Utomo. "STRIPED CATFISH (Pangasianodon hypophthalmus) (SAUVAGE, 1878) MOVEMENT AND GROWTH IN GAJAH MUNGKUR RESERVOIR, CENTRAL JAVA." Indonesian Fisheries Research Journal 21, no. 1 (2015): 27. http://dx.doi.org/10.15578/ifrj.21.1.2015.27-38.

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Movement is an essential mechanism by which mobile animals acquire the resources necessary for the successful completion of their life-cycles. Striped catfish (<em>Pangasianodon hypophthalmus</em>) contributed about 384 tonnes or approximately 40,04% to the total fish production in Gajah Mungkur reservoir. Diversion of Keduang River, one of Gajah Mungkur important inlets, could affect the the movement of this fish. The objective of this research were to analyze data related to the movement patterns and growth of <em>Pangasianodon hypophthalmus</em>. Field works were con

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Liu, Qingxia, Huiping Huang, Baohua Xu, et al. "Two Innovative Approaches to Optimize Vancomycin Dosing Using Estimated AUC after First Dose: Validation Using Data Generated from Population PK Model Coupled with Monte-Carlo Simulation and Comparison with the First-Order PK Equation Approach." Pharmaceutics 14, no. 5 (2022): 1004. http://dx.doi.org/10.3390/pharmaceutics14051004.

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The revised consensus guidelines for optimizing vancomycin doses suggest that maintaining the area under the concentration-time curve to minimal inhibitory concentration ratio (AUC/MIC) of 400–600 mg·h/L is the target pharmacokinetic/pharmacodynamic (PK/PD) index for efficacy. AUC-guided dosing approach uses a first-order pharmacokinetics (PK) equation to estimate AUC using two samples obtained at steady state and one-compartment model, which can cause inaccurate AUC estimation and fail to achieve the effective PK/PD target early in therapy (days 1 and 2). To achieve an efficacy target from th

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Moreno, Carol, Julio Delgado, John C. Byrd, et al. "Changes in Clinical Stage Identify Different Response Categories Among Patients in Iwcll PR: Analysis of CLL Patients on the Resonate Study." Blood 128, no. 22 (2016): 4384. http://dx.doi.org/10.1182/blood.v128.22.4384.4384.

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Abstract Background: In CLL/SLL, the iwCLL PR category is heterogeneous and complex to evaluate. Changes in clinical staging (Binet, Rai) have been proposed as a method to evaluate response in CLL (Montserrat, Cancer 1985; iwCLL, Ann Intern Med 1989). Ibrutinib (ibr), a first-in-class, once-daily inhibitor of Bruton's tyrosine kinase, is indicated by the FDA for the treatment of pts with CLL/SLL and allows for treatment without chemotherapy. Robust improvements in progression-free survival (PFS) and overall survival (OS) among ibr-treated pts in the phase 3 RESONATE trial demonstrated superior

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Broutin, Sophie, Francois Lemonnier, Aurélie Dupuy, et al. "Serum 2-Hydroxyglutarate in Angioimmunoblastic T Cell Lymphomas: A New Marker for IDH2 Mutation Detection and Monitoring." Blood 132, Supplement 1 (2018): 2898. http://dx.doi.org/10.1182/blood-2018-99-115893.

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Abstract Background: Angioimmunoblastic T cell lymphoma (AITL) is one of the most frequent peripheral T cell lymphoma, and has a poor prognosis. Neoplastic T cells originate from T follicular helper cells, and are admixed among a prominent microenvironment, making their identification sometimes difficult. IDH2 mutations are present in 20-30% AITL patients, where they often co-exist with TET2, DNMT3A and RHOA mutations. They affect almost exclusively the codon R172 of IDH2, providing to the IDH2 enzyme a neo-activity that converts α ketoglutarate (αKG) to D 2-hydroxyglutarate (2HG). D-2HG, the

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Hampel, Paul J., Kari G. Chaffee, Simonetto A. Douglas, et al. "Liver Dysfunction in Previously Untreated Chronic Lymphocytic Leukemia: Prevalence and Outcomes in a Large Cohort." Blood 128, no. 22 (2016): 5585. http://dx.doi.org/10.1182/blood.v128.22.5585.5585.

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Abstract INTRODUCTION: The prevalence of liver dysfunction in patients with previously untreated chronic lymphocytic leukemia (CLL) is unknown; knowledge of which may provide important context for emerging therapeutic options with possible hepatotoxicity. The impact of liver dysfunction on outcomes of CLL patients is not well described. METHODS: Between 09/1993 and 04/2016, previously untreated CLL patients seen in the Division of Hematology at Mayo Clinic at diagnosis (<12 months) and who had baseline assessment of at least one of the following liver function tests (LFTs): alkaline phospha

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Sharman, Jeff, Matthew Davids, Charles Michael Farber, et al. "Characteristics of Patients (Pts) with Chronic Lymphocytic Leukemia (CLL) Receiving Rituximab Monotherapy in the Connect® CLL Registry." Blood 128, no. 22 (2016): 5941. http://dx.doi.org/10.1182/blood.v128.22.5941.5941.

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Abstract Introduction: Rituximab (R) improves survival in CLL when added to intensive chemotherapy (such as fludarabine and cyclophosphamide [FCR]), and has been shown to improve progression-free survival when given as maintenance therapy following first- or second-line chemoimmunotherapy. However, early phase 2 studies demonstrated only modest activity of R monotherapy (R mono), particularly at standard dose, and its use as a single agent for pts with CLL has remained controversial. Here we describe the characteristics and outcomes of pts with CLL receiving R mono in a real-world setting. Met

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35

Hidayat, Thomas, Helman Nur Yusuf, Nurulludin Nurulludin, and Andina Ramadhani Putri Pane. "PARAMETER POPULASI KEPITING BAKAU (Scylla serrata) DI PERAIRAN PASAMAN BARAT." BAWAL Widya Riset Perikanan Tangkap 9, no. 3 (2018): 207. http://dx.doi.org/10.15578/bawal.9.3.2017.207-213.

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Pemanfaatan sumber daya kepiting bakau (Scylla serrata) di perairan Pasaman Barat sudah lama dilakukan oleh nelayan kecil dengan menggunakan bubu (tangkul) yang bersifat tidak selektif. Sebagai komoditi perikanan yang mempunyai nilai ekonomis penting di Indonesia, perlu dilakukan pengelolaan yang tepat agar ketersediaannya tetap berkelanjutan. Penelitian dilaksanakan bulan Januari - November 2016, dengan tujuan mengkaji beberapa parameter populasi sebagai bahan kebijakan pengelolaan kepiting bakau di perairan Pasaman Barat agar tetap lestari. Pengumpulan sampel dilakukan secara acak dari hasil

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36

Wagiyo, Karsono, Tirtadanu Tirtadanu, and Tri Ernawati. "PERIKANAN DAN DINAMIKA POPULASI RAJUNGAN (Portunus pelagicus Linnaeus, 1758) DI TELUK JAKARTA." Jurnal Penelitian Perikanan Indonesia 25, no. 2 (2019): 79. http://dx.doi.org/10.15578/jppi.25.2.2019.79-92.

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Teluk Jakarta merupakan salah satu daerah penangkapan dan habitat rajungan (Portunus pelagicus) di Indonesia. Permintaan pasar yang terus meningkat dan bersamaan dengan penurunan kualitas perairan mengakibatkan stok rajungan mengalami tekanan eksploitasi dan degradasi habitat. Agar pengelolaan sumberdaya rajungan di Teluk Jakarta tetap lestari, maka diperlukan penelitian mengenai perikanan dan dinamika populasi. Tujuan penelitian memperoleh data dan informasi mengenai daerah tangkapan, alat dan musim penangkapan, indeks kelimpahan, produksi dan komposisi, struktur ukuran, nisbah kelamin, kemat

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Mato, Anthony R., Brian T. Hill, Nicole Lamanna, et al. "Optimal Sequencing of Ibrutinib, Idelalisib, and Venetoclax in CLL: Results from a Large Multi-Center Study of 683 US-Patients." Blood 128, no. 22 (2016): 4400. http://dx.doi.org/10.1182/blood.v128.22.4400.4400.

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Abstract Introduction: Ibrutinib (Ibr), idelalisib (Ide), andvenetoclax (Ven), are all now approved for treating CLL patients in the US. However, in the absence of head-to-head comparator trials, there is limited guidance as to the optimal sequence of these therapies and to the best choice upon failure of first selected agent. To address these gaps in current literature, 9 large US cancer centers and the Connect CLL Registry collaborated to capture the experience of 683 CLLpts treated with kinase inhibitors (KIs) - focusing on optimal sequencing and patterns of failure. Patients and Methods: W

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Tadjuddah, Muslim, Budy Wiryawan, Ari Purbayanto, and Eko Sri Wiyono. "Parameter Biologi Ikan Kerapu (Epinephelus sp.) Hasil Tangkapan di Perairan Taman Nasional Wakatobi, Sulawesi Tenggara Indonesia (Biological Parameters of Grouper (Epinephelus sp.) Caught in Wakatobi National Park, Southeast Sulawesi, Indonesia)." Marine Fisheries : Journal of Marine Fisheries Technology and Management 4, no. 1 (2013): 11. http://dx.doi.org/10.29244/jmf.4.1.11-21.

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<p> </p><p class="MsoNormal" style="text-align: justify; text-indent: 1cm;"><span style="font-size: 10pt;" lang="sv" xml:lang="sv">Studi ini mengidentifikasi parameter ikan kerapu yang terdiri dari hubungan panjang-berat, tingkat kematangan gonad dan indeks kematangan gonad yang tertangkap dengan pancing hekaulu, bubu dan panah. Penelitian ini bertujuan </span><span style="font-size: 10pt;" lang="in" xml:lang="in">menganalisis karakteristik </span><span style="font-size: 10pt;" lang="sv" xml:lang="sv">parameter </span><span style="font-s

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Bendahmane, Mostafa, Moussa Chrif, and Said El Manouni. "Elliptic equations in weighted Sobolev spaces of infinite order with L 1 data." Mathematical Methods in the Applied Sciences 33, no. 1 (2009): 49–56. http://dx.doi.org/10.1002/mma.1149.

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SANTRA, S. B. "STUDY OF FINITE SIZE EFFECTS ON DIRECTED SPIRAL PERCOLATION." International Journal of Modern Physics B 17, no. 29 (2003): 5555–64. http://dx.doi.org/10.1142/s0217979203023252.

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Percolation under both directional and rotational constraints is studied numerically on the square lattice of different finite sizes L. The critical percolation threshold pc≈0.655 of the infinite network is determined by extrapolating the finite size data. The fractal dimension df of the infinite percolation clusters is found df≈1.72 from the finite size scaling, S∞~Ldf where S∞ is the mass of the infinite cluster. The critical exponents are estimated as a function of the system size L. It is seen that the results of smaller systems converge to that of the large systems. The results are then e

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Corcho, Adán J., and Lucas C. F. Ferreira. "Global existence for Schrödinger–Debye system for initial data with infinite ${L}^{2}$-norm." Quarterly of Applied Mathematics 73, no. 2 (2015): 253–64. http://dx.doi.org/10.1090/s0033-569x-2015-01371-4.

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Stamatovic, Biljana, and Goran Kilibarda. "Algorithm for Identification of Infinite Clusters Based on Minimal Finite Automaton." Mathematical Problems in Engineering 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/8251305.

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We propose a finite automaton based algorithm for identification of infinite clusters in a 2D rectangular lattice with L=X×Y cells. The algorithm counts infinite clusters and finds one path per infinite cluster in a single pass of the finite automaton. The finite automaton is minimal according to the number of states among all the automata that perform such task. The correctness and efficiency of the algorithm are demonstrated on a planar percolation problem. The algorithm has a computational complexity of O(L) and could be appropriate for efficient data flow implementation.

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O'Brien, Susan, Jeffrey A. Jones, Steven Coutre, et al. "Efficacy and Safety of Ibrutinib in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia with 17p Deletion: Results from the Phase II RESONATE™-17 Trial." Blood 124, no. 21 (2014): 327. http://dx.doi.org/10.1182/blood.v124.21.327.327.

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Abstract Background: Patients with chronic lymphocytic leukemia (CLL) with deletion of the short arm of chromosome 17 (del 17p) follow an aggressive clinical course and demonstrate a median survival of less than 2 years in the relapsed/refractory (R/R) setting. Ibrutinib (ImbruvicaTM), a first-in-class Bruton's tyrosine kinase (BTK) inhibitor, has been approved for previously treated patients with CLL and for patients with del 17p CLL. We report results from the primary analysis of the Phase II RESONATETM-17 (PCYC-1117-CA) study, designed to evaluate the efficacy and safety of single-agent ibr

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D'Auria, Bernardo, and Sidney I. Resnick. "The influence of dependence on data network models." Advances in Applied Probability 40, no. 1 (2008): 60–94. http://dx.doi.org/10.1239/aap/1208358887.

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Consider an infinite-source marked Poisson process to model end user inputs to a data network. At Poisson times, connections are initated. The connection is characterized by a triple (F, L, R) denoting the total quantity of transmitted data in a connection, the length or duration of the connection, and the transmission rate; the three quantities are related by F = LR. How critical is the dependence structure of the mark for network characteristics such as burstiness, distribution tails of cumulative input, and long-range dependence properties of traffic measured in consecutive time slots? In a

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D'Auria, Bernardo, and Sidney I. Resnick. "The influence of dependence on data network models." Advances in Applied Probability 40, no. 01 (2008): 60–94. http://dx.doi.org/10.1017/s000186780000238x.

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Consider an infinite-source marked Poisson process to model end user inputs to a data network. At Poisson times, connections are initated. The connection is characterized by a triple (F, L, R) denoting the total quantity of transmitted data in a connection, the length or duration of the connection, and the transmission rate; the three quantities are related by F = LR. How critical is the dependence structure of the mark for network characteristics such as burstiness, distribution tails of cumulative input, and long-range dependence properties of traffic measured in consecutive time slots? In a

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Brault, Marion, Maxime Annereau, Alina Danu, et al. "Outcomes of Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma Included in Phase I Clinical Trials." Blood 132, Supplement 1 (2018): 2992. http://dx.doi.org/10.1182/blood-2018-99-112919.

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Abstract INTRODUCTION The phase 1 selection for clinical trials of patients with relapsed or refractory Diffuse Large-B cell lymphoma (R/R DLBCL) with a potentially rapid tumor growth is a challenge. Prognostics' factors identification could help to better orient patients in appropriate clinical trials. This study is focused on DLBCL to evaluate their outcomes in phase I clinical trials. Our main objectives were to identify prognostic factors, attest the investigational drugs' safety and perform a preliminary assessment of drugs' efficacy. METHOD All consecutive patients with R/R DLBCL include

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Horvei, Paulina, Reona Sakemura, Michelle J. Cox, et al. "Targeting of CD19 By Tafasitamab Does Not Impair CD19 Directed Chimeric Antigen Receptor T Cell Activity in Vitro." Blood 134, Supplement_1 (2019): 2859. http://dx.doi.org/10.1182/blood-2019-130506.

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CD19 directed chimeric antigen receptor T cell (CART) therapy has shown remarkable activity in B cell lymphoma and acute lymphoblastic leukemia leading to the approval of two CART therapies. With the emergence of therapeutic anti-CD19 antibodies for the treatment of B cell malignancies, it remains to be elucidated whether such antibodies would interfere with the ability of CD19 targeting CARTs to exert their anti-tumor effect in a subsequent therapy. To address a part of this question, we investigated the potential for functional interference between the monoclonal anti-CD19 antibody tafasitam

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Archibald, William J., Timothy G. Call, Sara J. Achenbach, et al. "The Role of Imaging in Predicting Time to First Treatment and Overall Survival in Individuals with CLL-like High Count Monoclonal B-Cell Lymphocytosis." Blood 134, Supplement_1 (2019): 3037. http://dx.doi.org/10.1182/blood-2019-131154.

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Background: The 2008 International Working Group for CLL (IWCLL) criteria define MBL as a clonal B-cell disorder with a peripheral blood B-cell count of <5 x 109/L, in the absence of cytopenias(s), lymphadenopathy and/or organomegaly on physical examination, and no other concomitant lymphoproliferative disorder. In the presence of palpable lymphadenopathy and/or organomegaly, and a B-cell count of < 5 x 109/L, a diagnosis of small lymphocytic lymphoma (SLL) is established. A study by Gentile et al (Am J Hematol. 2013) reported that 29 out of 62 individuals with clinically identified MBL

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Ju, Hee Young, Ji Won Lee, Che Ry Hong, et al. "Pharmacokinetics of Fludarabine in Pediatric Hematopoietic Stem Cell Transplantation." Blood 124, no. 21 (2014): 2466. http://dx.doi.org/10.1182/blood.v124.21.2466.2466.

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Abstract Introduction: Fludarabine is a purine-analog which is effective for leukemic cells with lower toxicity. Thus it has been preferred for preparative regimens of hematopoietic stem cell transplantation (HSCT) recently. However, the pharmacokinetics of fludarabine in pediatric HSCT has not been studied before. This prospective study investigated the pharmacokinetics of fludarabine in children undergoing allogeneic HSCT, and attempted to establish the fludarabine administration in pediatric patients. Patients and Methods: Forty-three pediatric patients undergoing HSCT were enrolled to the

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Sharma, Ravinder, and Harsh Kumar. "Volumetric and Acoustic Studies of Interactions between L-Phenylalanine and 1-Hexyl-3-Methylimidazolium Bromide in Aqueous Solution." ECS Transactions 107, no. 1 (2022): 5227–33. http://dx.doi.org/10.1149/10701.5227ecst.

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Experimental density (ρ) and ultrasonic velocity (c) for phenylglycine in ( 0.01, 0.03, 0.05 and 0.05) mol.kg−1 aqueous solutions of 1-hexyl-3-methylimidazolium bromide at T = (313.15 and 318.15) K. Collected values for density and ultrasonic velocity were used to compute the apparent molar volumes (V f ), the apparent molar volumes at infinite dilution (), partial molar isentropic compression (K f ,s ) and partial molar isentropic compression at infinite dilution (). Also recorded data of these mixtures were utilized to calculate pair and triplet interaction coefficients. Such thermodynamic c

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