Dissertations / Theses: 'L-Met'

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Zhang, Shuai. "Physiological and Biochemical Aspects of Methionine Isomers and Precursors in Broilers." Diss., Virginia Tech, 2016. http://hdl.handle.net/10919/71816.

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Methionine (Met) is an essential amino acid for animals and also the first limiting amino acid in a broiler diet. The dietary supplemental Met sources include the natural isoform L-methionine (L-Met), the synthetic form DL-methionine (DL-Met) and the synthetic Met precursor DL-2-hydroxy-4 (methylthio)-butanoic acid (DL-HMTBA). The objective of this dissertation was to determine the effect of different dietary Met source supplementation and Met deficiency on a series of physiological and biochemical aspects, including growth performance, global DNA methylation and methyltransferase activity, blood antioxidant profile (e.g., acute phase protein, leukocyte count), intestinal nutrient transporter gene expression, Met converting enzyme gene expression and activity, oxidative stress markers, and a potential pathway related to amino acid signaling. To achieve this goal, male Cobb-500 broilers were raised from day of hatch (d0) to d35 post-hatch and fed a diet deficient in methionine and cysteine (Met + Cys) (control) or the same diet supplemented with 0.22% DL-Met, 0.22% L-Met or 0.31% DL-HMTBA (to provide 0.22% DL-Met equivalent) to meet Met + Cys requirements. Tissues (liver, breast muscle, duodenum, jejunum and ileum) and blood samples were collected at various ages from d0 to d35 for analysis. Met supplementation significantly improved body weight gain and feed efficiency compared to the Met deficient group, but no differences were observed among DL-Met, L-Met and DL-HMTBA for growth performance parameters (P > 0.05). Met supplementation had no effect on red blood cell packed cell volume, white blood cell differential count, hepatic total DNA methylation, DNA methyltransferase and Met oxidase activity, and had limited effects on activation of p70S6K, a key amino acid signaling protein (P > 0.05). Although dietary Met sources did not change oxidative status of the treated chickens, both L-Met and DL-Met but not DL-HMTBA supplementation decreased the level of acute phase protein serum amyloid A compared to the control group (P > 0.05). The effect of Met supplementation on gene expression of nutrient transporters and Met converting enzymes were complex and dynamic. Most of the target genes demonstrated tissue- and development-dependent expression patterns, with few significant treatment effects observed. L-Met and DL-Met but not DL-HMTBA supplementation enhanced the neutral amino acid transporters ATB0,+ and B0AT gene expression in various small intestinal segments. All three Met sources increased monocarboxylic acid transporter (MCT1) gene expression in the jejunum. DL-HMTBA and L-Met fed chickens showed greater hepatic L-HMTBA oxidase (HAO1) gene expression. DL-Met increased glutamic-oxaloacetic transaminase 2 (GOT2) gene expression in the duodenum. An in vitro study with tissue explants, however, did not demonstrate a similar gene expression pattern as that in the in vivo study. Lastly, RNA sequencing results illustrated that Met deficiency could lead to many differentially expressed genes but different supplemental Met sources had no influence on hepatic gene expression profiles. In conclusion, as common dietary supplemental Met sources, L-Met, DL-Met and DL-HMTBA exhibited similarity in impacting intestinal amino acid/peptide/monocarboxylic acid transporter gene expression and Met converting enzyme activity. The regulatory roles of Met as an antioxidant and nutrient signaling in cell metabolism were not affected by different dietary supplemental Met sources.
Ph. D.

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Lima, Analwik Tatielle Pereira de. "Alimento como met?fora, met?fora como alimento : a arte de nutrir uma educa??o complexa." Universidade Federal do Rio Grande do Norte, 2008. http://repositorio.ufrn.br:8080/jspui/handle/123456789/14301.

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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
Cette narrative fait le parcours d une recherche et de ses reflexions ici annonc? comme une odiss?e gastronomique et une g?ografie gourmante , dont les elements interpretatifs rendent possible concevoir qu une lecture de la m?taphore et de la st?thique alimentaire puissent contribuer pour penser une ?ducation sensible, complexe, une education guid?e par une experimentation esth?tique de la condition humaine, qui provoque les sens, qui permettent ?voquer et r?cuperer les connaissances et les savoirs pertinents, et qui confirme l indissociabilit? du sujet dans ses plusieurs poles : nature et culture, ?motion et raison. Comme contribution epist?mologique, la dissertation, cherche ?tendre la compr?hension d ?tudes qui abordent le Corp, l Aliment, la M?taphore, l Esth?tique et l ?ducation, en d?clanchant des relations entre les espaces acad?micien et cotidien, en exp?rimentant d autres formes de sentir, penser et d ?tre dans le monde. Pouss?e par une raison gourmande, et comme dans un rituel de pr?paration d aliment, j opte par les r?lations transversales des savoirs ; je construis un dialogue entre les auteurs de domaine de connaissances multiples, comme la Filosophie, l Antropologie, l ?tologie et l ?ducation, en travaillant une reconstruction de concepts. Pour la t?che de cette odiss?e gastronomique, je d?couvre l approche entre un programme, comme m?thode, et un livre de recettes culinaires herm?tiques. J ai choisi de construir des estrat?gies m?todologiques qui indiquent les chemins sur les quelles l imagination, la cr?ativit? et la r?invention, non seulement puissent mais doivent servir comme des ?piceries qui empr?gne d odeurs, de saveurs et de couleurs la connaissance, sans laisser de c?t? la rigueur, principe in?gociable dans une science ouverte. J ai choisi, pour m accompagner dans cet ?tude, des sages, des scientistes et des po?tes, entre eux je fais remarquer Michel Onfray, Boris Cyrulnik, Merleau-Ponty, Edgar Morin e Concei??o Almeida. Avec eux, j ai d?ssin? des cartes, go?t? des g?ographies, des terres, des ciels. J ai fr?quenter des histoires et des personnages concrets et imaginaires; j ai convoqu? des souvenirs acumul?s pendant l enfance, avec ses trames, ses textures, ses saveurs, ses parfuns, ses couleurs, ses images, ses gestes, ses mots et ses silences, o? le corp devient un m?diateur d acc?s ? la connaissance. Comme artifice compl?mentaire pour suivre la route, je parie sur le rapport fondamental entre le corp, l aliment, la m?taphore, l esth?tique et l ?ducation, je m utilise du Cin?ma, en cherchant d apprendre dans cet art, une ?xistentialit? humaine par le rapport entre la vie, l aliment et les personnages. Finalement, je reaffirme l importance de nourir des affections par une formation et une mani?re de penser capables de conect? des connaissances d univers dinstingu?s, et qui contribuent pour une conscience de la condition humaine et l apprentissage d une ?ducation de la vie et pour la vie
Esta narrativa descreve o percurso de uma pesquisa e as reflex?es dela decorrentes aqui anunciadas como uma odiss?ia gastron?mica e uma geografia gulosa , cujos elementos interpretativos tornem poss?vel conceber que uma leitura da met?fora e da est?tica alimentar possam contribuir para se pensar uma educa??o sens?vel, complexa, uma educa??o guiada por uma experimenta??o est?tica da condi??o humana, que aciona os sentidos, permitindo evocar e rememorar conhecimentos e saberes pertinentes, e que reitera a indissociabilidade do sujeito em seus v?rios p?los constituintes: natureza e cultura, emo??o e raz?o. Como contribui??o epistemol?gica, a disserta??o, busca ampliar a compreens?o de estudos que abordam o Corpo, o Alimento, a Met?fora, a Est?tica e a Educa??o, acionando inter-rela??es, entre os espa?os acad?mico e cotidiano, experimentando outras formas de sentir, pensar e estar no mundo. Impulsionada por uma raz?o gulosa, e como num ritual de prepara??o do alimento, escolho transversalizar saberes; construo um di?logo entre autores de ?reas de conhecimentos m?ltiplos, como a Filosofia, a Antropologia, a Etologia e a Educa??o, operando uma ressignifica??o de conceitos. Para a empreitada dessa odiss?ia gastron?mica, descubro a aproxima??o entre um programa enquanto m?todo e um livro de receitas culin?rias herm?ticas. Optei por construir estrat?gias metodol?gicas que indicassem caminhos nos quais a imagina??o, a criatividade e a reinven??o possam e devam servir como especiarias, impregnando de odores, sabores e cores o conhecimento, sem abrir m?o do rigor, princ?pio inegoci?vel a uma ci?ncia aberta. Escolhi para me acompanhar s?bios, cientistas e poetas, entre os quais destaco Michel Onfray, Boris Cyrulnik, Merleau-Ponty, Edgar Morin e Concei??o Almeida. Com eles, desenhei mapas, provei geografias, terras, c?us. Convivi com hist?rias e personagens concretos e imagin?rios; convoquei lembran?as acumuladas na inf?ncia, com suas tramas, texturas, sabores, aromas, cores, imagens, gestos, palavras e sil?ncios, em que o corpo torna-se um mediador de acesso ao conhecimento. Como artif?cio complementar para prosseguir viagem, apostando na rela??o fundamental entre corpo, alimento, met?fora, est?tica e educa??o, recorro ao cinema, buscando apreender nessa arte uma existencialidade humana por meio da rela??o entre vida, alimento e personagens. Por fim, reafirmo a import?ncia de nutrir afetos atrav?s de uma forma??o e de um modo de pensar capazes de solidarizar conhecimentos separados, e que contribuam para uma consci?ncia da condi??o humana e para o aprendizado de uma educa??o da vida e para a vida

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Schenker, Teresa [Verfasser], Konrad L. [Akademischer Betreuer] Streetz, and Christoph [Akademischer Betreuer] Wruck. "Die Expression von MET im Rahmen chronischer Lebererkrankungen / Teresa Schenker ; Konrad L. Streetz, Christoph Wruck." Aachen : Universitätsbibliothek der RWTH Aachen, 2018. http://d-nb.info/117181853X/34.

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Stöber, Barbara. "Charakterisierung des Transportes der Aminosäuren L-[Methyl-3H]-Methionin (Met) und O-(2-[18F]fluorethyl)-L-Tyrosin (FET) in humane Lymphozyten, Makrophagen und Kolonkarzinomzellen." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973390352.

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Backes, Karin Lilian Hagemann. "Mar de poeta : a met?fora do oceano nas l?ricas de Cec?lia Meireles e Sophia Andresen." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2009. http://tede2.pucrs.br/tede2/handle/tede/1914.

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Nosso objetivo ? analisar o oceano como met?fora nas l?ricas de Cec?lia Meireles (1901-1964) e Sophia Breyner Andresen (1919-2004), a partir do texto do fil?sofo Paul Ricoeur, A met?fora viva. A proposta de Ricoeur ? demonstrar que a compet?ncia metaf?rica est? incompleta sem o apoio psicol?gico da imagina??o e do sentimento, em que a imagem ? tomada como o ?ltimo momento de uma teoria sem?ntica. Sua teoria da compet?ncia metaf?rica ser? utilizada para comprovar como cada poeta emprega essa figura de linguagem para atingir determinados prop?sitos em suas l?ricas, com base em influ?ncias comuns. Cec?lia est? orientada na dire??o do m?stico e busca a transcend?ncia, enquanto Sophia, por conta da cultura grega de raiz cl?ssica, ? m?tica e imanente. As met?foras do mar, nas duas obras, se prestam como um meio po?tico privilegiado desses posicionamentos.

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Bicicgo, Cleber. "Ler o pol?tico no modo como se l? as met?foras de leitura no discurso da cr?tica liter?ria." Universidade Federal da Fronteira Sul, 2014. https://localhost:443/handle/prefix/90.

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A partir do conceito de met?fora e da no??o de efeito metaf?rico fundamentados no trabalho do franc?s Michel P?cheux, esta disserta??o prop?e analisar as met?foras de leitura no discurso da Cr?tica Liter?ria, para compreender o funcionamento do pol?tico-ideol?gico no discurso metaf?rico. A disputa ideol?gica na produ??o do conhecimento, segundo P?cheux, est? na materialidade das met?foras que uma ci?ncia usa para ?compreender e se fazer compreender?. Questionando, ent?o, as met?foras de leitura, como est?o formuladas no discurso da Cr?tica Liter?ria, o presente estudo leva a considerar que a constitui??o hist?rico-discursiva das met?foras n?o possui uma origem, e sim diferentes formas de funcionamento, conjunturalmente tomadas pela disputa entre diferentes concep??es de leitura. A partir desse entendimento, surgem duas considera??es: a primeira ? que n?o existe uma mem?ria homog?nea que estaria na ?origem? da met?fora; a segunda ? que a met?fora ? produzida conforme o contexto de produ??o, podendo se deslocar para dentro de diferentes forma??es discursivas. O funcionamento do discurso metaf?rico marca um posicionamento pol?tico-ideol?gico, cujo resultado aponta para a rela??o entre uma pr?tica cient?fica e uma pr?tica pol?tica, materializadas nas met?foras de leitura. Trata-se, dessa maneira, de um estudo que problematiza o discurso metaf?rico a partir do posicionamento pol?tico-ideol?gico que o sujeito cr?tico liter?rio assume ao interpretar. Esta pesquisa traz uma contribui??o importante para os estudos sobre a met?fora, na perspectiva da An?lise de Discurso, al?m de subsidiar a pr?pria Cr?tica Liter?ria, na compreens?o do processo hist?rico que marca as met?foras que ela usa para compreender o funcionamento dos sentidos numa obra liter?ria.
From the concept of metaphor and metaphorical effect?snotion based on Michel P?cheux?swork, this dissertation proposes to examine the metaphors of reading on the discourse of literary criticism to understand the functioning of the political-ideological discourse in metaphorical discourse. The ideological struggle in the production of knowledge, according to P?cheux, is the materiality of metaphor that a science uses ?to understand and be understood?.So, questioning the metaphors of reading, as they are formulated in the discourse of literary criticism, this study leads to the conclusion that historical and discursive constitution of metaphors does not have a source, but different ways of working, conjuncturally taken by the dispute between different conceptions of reading. Based on this understanding, two considerations arise: the first is that there is no homogeneous memory that would be the ?origin? of metaphor; the second is that the metaphor is produced according to the context of production and can move within different discursive formations. The functioning of metaphoric discourse marks a political-ideological stance which the results points to the relationship between scientific practice and political practice, embodied in the metaphors of reading. It is, thus, a study that discusses the metaphoric discourse from the political-ideological stance that the literary critic subject assumes when he interprets. This research makes an important contribution to studies on metaphor, from the perspective of discourse analysis, in addition to supporting the literary criticism itself on understanding the historical process that marks the metaphors it uses to understand the functioning of the senses in a literary work.

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Zimmer, Stephan. "Charged Higgs Boson Studies in the Channel pp→a1h±→4b+l+MET in the Next-to MSSM (NMSSM) with the ATLAS Experiment." Thesis, Uppsala universitet, Högenergifysik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-119324.

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Next-to-minimal super-symmetric extensions of the Standard Model (SM) predict the existence of several non-SM like Higgs bosons. The process pp→a1h±→4b+W involves the production and the decay of a spin-0 charged Higgs boson and a CP-odd Higgs boson a1 which can have a sizable cross section in the NMSSM. The invariant masses of these intermediate bosons can be reconstructed from the four momenta of the final state particles using mass minimization algorithms. This thesis presents a cut-based analysis of two mass scenarios and specialized algorithms that are capable of recovering the signal in a large background arising from Standard Model processes such as ttbar. The analysis is tested with a realistic ATLAS detector simulation investigating trigger efficiencies and probing several jet reconstruction algorithms.

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Berger, Evelin [Verfasser], and Lothar [Akademischer Betreuer] Jänsch. "Time-resolved characterization of the HGF/Met response and the influence of L. monocytogenes InlB on the physiological phosphoproteome / Evelin Berger ; Betreuer: Lothar Jänsch." Braunschweig : Technische Universität Braunschweig, 2013. http://d-nb.info/1175822671/34.

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Truter, Leani. "Obesiteit se verband met motoriese en fisieke ontwikkeling en die effek van 'n multidissiplinêre fisieke aktiwiteitsintervensie daarop by 10– tot 12–jarige kinders / Truter L." Thesis, North-West University, 2011. http://hdl.handle.net/10394/7300.

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The increasing prevalence of childhood obesity worldwide is viewed as a global epidemic (World Health Organization, 2010). It is associated with a variety of health problems as well as physical– (cardio–respiratory endurance, flexibility, muscular strength, muscular endurance, and body composition), and motor proficiency (fine manual control, manual coordination, body coordination, and strength–and–agility) (Asayama et al., 2003:644; Okely et al., 2004:242; Tokmakidis et al., 2006:870). As far as the South African context is concerned, there is little research examining these relationships and the effect of physical intervention there upon, in nine– to 12–year old children. The first and second objectives of this study were to determine whether obesity would influence the physical– and/or the motor proficiency of nine– to 12–year–old South African children. The third and fourth objectives of this study were to determine the effect of a multidisciplinary intervention on the physical– and the motor proficiency of nine– to 12–year–old obese children. For objectives one and two, a cross–sectional study was performed on 280 children (128 boys and 152 girls), with an average age of 10.6 years (±1.05). Anthropometric–, physical– and motor measurements were obtained by the 'Fitnessgram' (Meredith & Welk, 1999) and the 'Bruininks–Oseretsky Test of Motor Proficiency–II' (Bruininks & Bruininks, 2005). Body mass index (BMI) cut–off points were used to classify the children as normal, overweight, or obese (Cole et al., 2000). The data was analysed with regard to the above–mentioned objectives with the Statistica computer program, by means of descriptive statistics, Spearman rank correlations, and variance analyses. The results show that the physical fitness variables, cardio–respiratory endurance and muscular strength, particularly leg muscular strength, showed significant decreases with an increase in BMI. A progressive, but insignificant, decrease was found in muscular endurance with an increase in BMI, while flexibility showed the weakest relationship to BMI. The motor variables strength–and–agility weakened significantly with an increase in BMI, while fine manual control, manual coordination, and body coordination showed the weakest relationships to BMI. Variance analysis showed further significant relationships among BMI, cardio–respiratory endurance, muscular strength, and running speed–and–agility (p<0.05). It can be concluded that health–promoting physical fitness and the motor proficiency of young South African children are negatively influenced by obesity and intervention strategies are recommended to promote the quality of life of such children. For objectives three and four, an availability random sample of 37 experimental subjects, with an average age of 11 years (±0.99) was taken, where 20 subjects (seven boys and 13 girls) took part in a multidisciplinary intervention programme, and 17 subjects (six boys and 11 girls) formed part of a control group. Body composition, physical–, and motor proficiency were analysed by the 'Fitnessgram' (Meredith & Welk, 1999) and the 'Bruininks–Oseretsky Test of Motor Proficiency–II' (Bruininks & Bruininks, 2005) during baseline measurements, on completion of the intervention programme, and after a follow–up period of three months. The results, which were analysed with a repeated–measures analysis, Bonferroni–post–hoc analysis, and dependent and independent t–tests, show that the intervention programme brought about a significant change in all the body composition variables, excluding body height. Flexibility, muscular strength, and abdominal muscular endurance, as well as one of the four fine manual control test items (folding paper), two of the 12 body coordination test items (tapping feet and fingers - opposite sides synchronised, and standing on one leg on a line - eyes closed), and six of the seven strength and agility test items (shuttle run, stepping sideways over a balance beam, one–legged stationary hops, one–legged side hops, two–legged side hops, and sit–ups), showed significant differences from the control group on completion of the intervention programme. The results indicate that the intervention brought about differences in body composition and physical– and motor proficiency and also showed a sustainable effect over a period of three months on body fat percentage, subscapular skinfold and leg muscular strength. From this, it can be deduced that young obese children need sustained guidance to be able to maintain the lifestyle adaptations that are required by obesity interventions. It can be concluded that the physical– and motor proficiency of children is negatively influenced by obesity, that a multidisciplinary intervention programme improves the body composition profile of obese children and has a positive effect on the physical– and the motor proficiency of obese nine– to 12–year old South African children, although the effect is not sustainable without ongoing, controlled intervention.
Thesis (Ph.D. (Kinderkinetics))--North-West University, Potchefstroom Campus, 2012.

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Oliveira, Alzir. "O latim, uma l?ngua morta?: uma met?fora em an?lise: o olhar da ling??stica aplicada e suas implica??es para o ensino." Universidade Federal do Rio Grande do Norte, 2008. http://repositorio.ufrn.br:8080/jspui/handle/123456789/16286.

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The focus of this research is the teaching of the Latin language. Due to the fact that its teaching has been facing a growing crisis in the last four decades, which currently persists, we ponder about external and internal causes of its decline, aiming at pointing out an alternative that enable us to find a way out of this situation. So, our research questions mainly concern how the teaching of Latin is viewed amongst the academic society, also investigating if it has kept up with the development of the scientific reflection about human language and the new approaches on language teaching. Furthermore, we analyse the contribution that the study of Latin can provide to the academic formation of language teachers and try to identify the areas of knowledge that can contribute to a reshaping of its teaching. Based on these guidelines, we have established as the goals of this research: 1) to reflect about the current situation of the teaching of Latin and the causes of its decline; 2) to determine its social representation among teachers and students of the Language Courses, as a way of defining the role it fulfills in the academic formation of teachers; 3) to accomplish an exploratory study of some handbooks that show alternative proposals on how to teach Latin, in order to detect their adequacy to current times and to the goals of the academic study of languages; 4) to offer an alternative proposal on how to teach Latin that takes into account the principles of Applied Linguistics, considering the socio-historical and cultural aspects of the language, enabling it to meet the requirements set by modern times. This research is divided into two parts. The first part presents the theoretical framework. We map the studies about Latin teaching inside and outside Brazil and argue against the concept of Latin being a dead language, presenting arguments set on changing this view. Then we describe and comment the notions of literacy, genre and culture, which helped us understand the reasons for the decline of the teaching of Latin and to point out suitable ways to overcome the crisis. The second part is dedicated to reflecting on the literacy practices in Latin teaching. We began by examining the answers to the questionnaires given to students and teachers about the view of Latin in the Language Courses; then we reflect on the teaching-learning of Latin as an academic literacy practice followed by an analysis of the didactic material used in teaching Latin. Finally, we suggest an approach of the familiar letter genre in ancient Rome as a means of teaching Latin in a contextualized way
O foco deste trabalho ? o ensino da l?ngua latina. Partindo da constata??o de que esse ensino vem enfrentando, desde as ?ltimas quatro d?cadas, uma situa??o crescente de crise, que perdura nos dias atuais, refletimos sobre as causas externas e internas do seu decl?nio, com o objetivo de apontar alguma alternativa para a sa?da da crise em que se encontra. Assim, nossas quest?es de pesquisa se preocupam, antes de mais nada, em verificar como o ensino do latim ? visto no meio acad?mico, investigando ainda se este ensino tem acompanhado os progressos da reflex?o cient?fica sobre o fen?meno da linguagem humana e sobre as novas abordagens do ensino de l?nguas. Al?m disso, discutimos acerca da contribui??o que o estudo do latim pode oferecer para a forma??o acad?mica em Letras e procuramos identificar os campos do saber que podem contribuir para um redimensionamento do seu ensino. Em raz?o dessas quest?es, estabelecemos como objetivos do trabalho 1) Refletir sobre a situa??o atual do ensino do latim e sobre as causas do seu decl?nio; 2) Identificar sua representa??o social no meio acad?mico discente e docente do Curso de Letras, como forma de contribuir para a defini??o do papel que lhe cabe na forma??o docente; 3) Fazer um estudo explorat?rio de alguns comp?ndios que apresentam propostas alternativas de didatiza??o do latim, com o intento de verificar sua adequa??o ? nossa realidade e aos objetivos da forma??o em Letras; 4) Apresentar uma proposta alternativa de ensino do latim que leve em conta as contribui??es da Ling??stica Aplicada e que, contemplando os aspectos s?cio-hist?ricos e culturais da l?ngua, seja capaz de atender as exig?ncias da modernidade e da sua inser??o no curr?culo de Letras. O trabalho est? dividido em duas partes. A primeira constitui o quadro te?rico. Nela procedemos a um mapeamento introdut?rio dos estudos sobre o ensino do latim no Brasil, com uma breve incurs?o no panorama europeu e norte americano. Em seguida, tecemos considera??es sobre a concep??o do latim como l?ngua morta, apresentando argumentos para uma revis?o desta met?fora. Finalizamos com a apresenta??o dos conceitos de letramento, g?nero e cultura, que fundamentam teoricamente a nossa proposta de abordagem do ensino do latim. A segunda parte ? destinada ? reflex?o sobre as pr?ticas de letramento no ensino do latim. Come?amos examinando as respostas aos question?rios aplicados a alunos e professores, com o intuito de detectar as representa??es acerca do latim no meio acad?mico de Letras, refletimos sobre o ensino-aprendizagem do latim como uma pr?tica de letramento acad?mico, detendo-nos a seguir na an?lise de materiais utilizados para a didatiza??o do latim. Por fim, sugerimos uma abordagem do g?nero carta familiar em Roma como instrumento de ensino do latim de uma forma contextualizada

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Santos, Acassio Rocha. "Estudo de clusters met?licos de alum?nio-s?dio, alum?niopot?ssio, alum?nio-l?tio e s?dio-l?tio pelas abordagens de algoritmos gen?ticos, c?lculos qu?nticos e an?lise topol?gica." PROGRAMA DE P?S-GRADUA??O EM QU?MICA, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/23542.

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O estudo te?rico de clusters met?licos tem despertado um interesse consider?vel, devido ? possibilidade de criar novas ligas de materiais em nanoescala, as chamadas "nanoligas". Pesquisas sobre nanoligas desempenham papel significativo na Ci?ncia de Materiais, pois, entre seus objetivos mais importantes, est?o o de prever a estabilidade das estruturas, seus modos de crescimento, bem como o de auxiliar a interpreta??o de medidas espectrosc?picas e outras medi??es experimentais. Nesse contexto, um grande n?mero de m?todos foi relatado nos ?ltimos anos para a otimiza??o do m?nimo global de grupos at?micos e moleculares, sendo um dos mais utilizados atualmente o do Algoritmo Gen?tico (doravante, GA), o qual baseia-se em princ?pios relacionados a processos evolutivos, em operadores inspirados na Teoria da Evolu??o e na Gen?tica, isto ?, na recombina??o, muta??o e sele??o natural. Particularmente, o GA com a implementa??o do potencial Gupta tem se mostrado eficiente na busca de solu??es ??timas? em problemas de otimiza??o de clusters met?licos. Esta disserta??o ? composta por cap?tulos de introdu??o, de metodologia, de abordagem te?rica (Cap. 1, 2 e 3); e tamb?m por cap?tulos que cont?m artigos sobre o tema proposto (Cap. 4, 5 e 6). No primeiro artigo (Cap. 4), analisaram-se clusters bimet?licos AlxNay (x+y?55) por meio da aplica??o do GA com a implementa??o do potencial Gupta. Com base tamb?m na aplica??o do GA, no segundo cap?tulo (Cap. 5) foram estudados clusters de AlxLiy e AlxKy (x+y ? 55). Em ambos os trabalhos, para elevar a efici?ncia do GA, introduziu-se mais dois operadores: o Aniquilador e o Hist?ria. Ao serem comparadas as estruturas obtidas por meio do GA com potencial Gupta para clusters de alum?nio puro, l?tio puro e alum?nio-l?tio com resultados recentes da literatura, verificou-se que para os sistemas Al2, Al3, Al6, Al8, Al9, Li5, Li6, Li7, Al1Li5, Al1Li7 e Al1Li8 as geometrias obtidas foram muito semelhantes ?quelas resultantes de c?lculos de funcional de densidade e ab initio[como CCSD(T)]. No terceiro artigo (Cap. 6), analisou-se um novo algoritmo gen?tico qu?ntico (Q-GA) para pequenos sistemas de clusters NaxLiy com (x+y ? 10). Constatou-se que o Q-GA apresenta maior efici?ncia na busca do m?nimo global em rela??o ao GA com o potencial Gupta. Isso porque o primeiro utiliza m?todo qu?ntico, enquanto o segundo usa um m?todo cl?ssico. Por ser mais preciso, o Q-GA possui uma abrang?ncia menor. Neste artigo, al?m de c?lculos ab inito, tamb?m foram realizados c?lculos topol?gicos a partir da Teoria Qu?ntica de ?tomos em Mol?culas (QTAIM) para as estruturas Na1Li5, Na2Li4, Na3Li3, Na4Li2 e Na5Li1, obtidas pelo Q-GA. Nessas estruturas, chama a aten??o o fato de n?o haver caminho de liga??o envolvendo diretamente os metais, sendo unidos por pseudo?tomos, com exce??o do Na5Li1. Algumas intera??es at?micas n?o foram indicadas pelo caminho de liga??o e sua an?lise foi feita pelo ?ndice de deslocaliza??o (DI). No sistema Na1Li5, os pares at?micos Na1-Li2 e Na1-Li6 t?m as intera??es mais fortes (e equivalentes ? do sistema NaLi) de todos os pares Na-Li de todos clusters NaxLiy(x+y=6); ao mesmo tempo, os outros pares Na-Li t?m intera??es dez vezes mais fracas do que aquelas do sistema NaLi. As intera??es Na-Na dos clusters Na4Li2 e Na5Li1 s?o as mais fortes quando comparadas com sistemas puros. Por fim, verificou-se que a f?rmula do grau de degeneresc?ncia do ?ndice de aromaticidade D3BIA e a carga at?mica indicaram que os ?tomos de l?tio mais pr?ximo ao ?tomo de s?dio transferem carga para esse ?ltimo.
The theoretical study of metal clusters has drawn considerable interest due to the possibility of creating new alloys from materials in nanoscale, the so-called "nanoalloys". Research on nanoalloys has had an important role in materials science, since, among some of its most relevant objectives, we may find the prediction of stability in structures, their manners of growth and further assistance in the interpretation of spectroscopic and other experimental measures. In this context, several methods have been reported in the last few years towards the global minimum optimization of atomic and molecular groups, where the Genetic Algorithm (henceforth GA) is currently considered one of the most used methods, whilst based on principles related to evolutionary processes as well as operators inspired by the Theory of Evolution and Genetics, i. e., by recombination, mutation and natural selection. The GA method in particular, and altogether with the implementation of the Gupta potential, has become efficient in the search for ?optimal? solutions for optimization problems in metallic clusters. The present dissertation is composed of chapters consisting of introduction, methodology and theoretical considerations (Chap. 1, 2 and 3), as well as of chapters containing articles on the proposed subject (Chap. 4, 5 and 6). In the first article (Chap. 4), we may find the analysis of AlxNay (x + y ? 55) bimetallic clusters through the Genetic Algorithm method with the implementation of the Gupta potential. Also based on the GA application, in the following chapter (Chap. 5) we may find a study regarding AlxLiy e AlxKy (x+y ? 55) clusters. In both works, in order to improve GA efficiency, two additional operators have been introduced: Annihilator and History. By being compared to structures obtained by means of GA with Gupta potential for pure aluminum, pure lithium and aluminum-lithium clusters in recent results from literature, it has been verified that, regarding systems Al2, Al3, Al6, Al8, Al9, Li5, Li6, Li7, Al1Li5, Al1Li7 e Al1Li8, the obtained geometries were very similar to those resulting from density functional and ab initio calculations [such as CCSD(T)]. In the third chapter (Chap. 6), we analyzed a new quantum genetic algorithm (QGA) for small cluster systems NaxLiy with (x+y ? 10). It has been observed that Q-GA presents an improved efficiency towards a global minimum regarding the GA with the Gupta potential. That has been the case since the former uses the quantum method, while the latter uses a classic method. More specifically, the Q-GA has a narrower scope. In this article, besides ab initio calculations, topological calculations were performed as well, grounded on the Quantum Theory of Atoms in Molecules (QTAIM) for the structures Na1Li5, Na2Li4, Na3Li3, Na4Li2 e Na5Li1 obtained by the Q-GA. In these structures, it is evident that there is no bonding path between the metals, since they are bonded by pseudo atoms, with the exception of the Na5Li1. Some of the atomic interactions have not been suggested by the bonding path, being their analysis performed according to the delocalization index (DI). In the Na5Li1 system, the atomic pairs Na1-Li2 and Na1-Li6 have the strongest interactions (equivalent to the NaLi system) of all Na-Li pairs in all of the NaxLiy (x+y=6) clusters; concurrently, other Na-Li pairs bear interactions ten times weaker than those from the NaLi system. The Na-Na interactions from the clusters Na4Li2 e Na5Li1 are stronger when compared to pure systems. Finally, it has been verified that the degree of degeneracy formula of the aromaticity index D3BIA and the atomic charge suggest that the lithium atoms that are closer to the sodium atom transfer charge to the latter.

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Maciel, Thais Aline Oliveira. "Estudo da influ?ncia de linf?citos TCD-8 e das c?lulas NK em casos de carcinoma epiderm?ide de l?bio inferior sem met?stase e com met?stase e sua rela??o com a progress?o da les?o." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17133.

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The presence of inflammatory cells within the tumor microenvironment plays a dual role that may contribute both to the progression and for inhibition of tumor growth. Recent studies suggest that the quality, not the quantity, of the inflammatory infiltrate is the most important determinant for prognosis. Therefore, TCD8 cells and natural killer cells are the main effector cells in combating cancer. The aim of this study was to assess, through the immunohistochemical study, the expression of TCD8 lymphocytes and NK cells in epidermoid carcinoma (EC) of the lower lip. The sample consisted of 32 specimens of EC of the lower lip, of which 16 had regional lymph node metastasis, and the 16 remaining, free of metastases. The total number of positive cells at the front of invasion were evaluated quantitatively and the results were related to clinical TNM staging, histological grade of malignancy and prognostic factors. It was observed for the group with metastasis, prevalence of stages III and IV (p<0.0001). Most patients with metastasis, had a high grade of malignancy (p=0.006). Most cases classified as high grade of malignancy had stages III and IV (p=0.032). Of the total sample, there were three cases of recurrence and five with death, however these variables were not statistically significant when associated with clinicopathological parameters. The immunostaining of CD8 and CD57, respectively, showed no statistically significant association with any of the clinicopathological parameters studied, metastasis (p=0.346, p=0.622), TNM classification (p=0.146, p=0.576), histological grade of malignancy (p=0.936, p=936), recurrence (p=0.075, p=0.075) and death (p=0.897, p=0.856). Believing in the function of the immunological system against malignant cells, it is concluded that the TD8 lymphocytes and NK cells, would be acting in the control of the progression of malignant neoplasms, but not in isolated manner
A presen?a de c?lulas inflamat?rias dentro do microambiente tumoral exerce um papel dual podendo contribuir tanto para a progress?o como para a inibi??o do crescimento do tumor. Estudos recentes sugerem que a qualidade, e n?o a quantidade, do infiltrado inflamat?rio ? o determinante mais importante para o progn?stico. Portanto, as c?lulas TCD8 e as c?lulas natural killer (NK), s?o as principais c?lulas efetoras no combate do c?ncer. O objetivo desse trabalho foi avaliar, atrav?s do estudo imunoistoqu?mico, a express?o dos linf?citos TCD8 e das c?lulas NK em carcinoma epiderm?ide (CE) de l?bio inferior e sua rela??o com a progress?o da les?o. A amostra foi composta por 32 esp?cimes de CE de l?bio inferior, dos quais 16 apresentavam met?stase linfonodal regional, e os 16 restantes, livres de met?stase. O total de c?lulas positivas no front de invas?o foram avaliados de forma quantitativa e os resultados obtidos foram relacionados com estadiamento cl?nico TNM, grada??o histopatol?gica de malignidade e fatores progn?sticos. Observou-se para o grupo com met?stases, preval?ncia dos est?gios III e IV (p<0,0001). A maioria dos casos com met?stase, apresentava alto grau de malignidade (p=0,006). A maioria dos casos classificados como de alto grau de malignidade apresentava est?gios III e IV (p=0,032). Do total da amostra, houve tr?s casos com recidiva e cinco com ?bito, no entanto essas vari?veis n?o apresentaram diferen?a estatisticamente significativa quando associadas a par?metros clinico-patol?gicos. A imunoexpress?o do CD8 e do CD57, respectivamente, n?o apresentaram associa??o estatisticamente significativa com nenhum dos par?metros cl?nico patol?gicos estudados, met?stases (p=0,346; p=0,622); estadiamento cl?nico TNM (p=0,146; p=0,576) grada??o histopatol?gica de malignidade (p=0,936; p=936); recidiva (p=0,075; p=0,075) e ?bito (p=0,897; p=0,856). Acreditando na fun??o que o sistema imunol?gico possui frente a c?lulas malignas, conclui-se que os linf?citos TCD8 e as c?lulas NK, estariam atuando no controle da progress?o de neoplasias malignas, mas n?o de forma isolada

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Mottin, L?via Pretto. "An?lise da produ??o metaf?rica no Brazilian English Learner Corpus." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2012. http://tede2.pucrs.br/tede2/handle/tede/2078.

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This study brings together theoretical assumptions from Corpus Linguistics and metaphor theories and aims at verifying variation in metaphor production by Brazilian English learners following a corpus-based approach. The corpus used for the investigation was the Brazilian English Leaner Corpus (BELC) (PACHECO, 2010), which is composed of four proficiency levels: (i) Beginner, (ii) Pre-Intermediate, (iii) Intermediate, and (iv) Advanced; and three types of task: (i) task 1 (descriptive text with personal information in 1st person), (ii) task 2 (descriptive text with personal information in 3rd person), and (iii) task 3 (narrative text about a trip). The corpus was manually annotated based on the procedures established by Cameron (2003) and by the Pragglejaz Group (2007). The metaphor frequency was later calculated using the software WordSmith tools (SCOTT, 2012), more specifically, the Concord tool. The research was organized in the following stages: (i) manual annotation of metaphor occurrences; (ii) extraction of metaphor frequency in the whole corpus and in its subcorpora; (iii) comparison of frequencies of use of linguistic metaphors in the three proficiency levels subcorpora; (iv) comparison of frequencies of use of linguistic metaphors in the four textual types subcorpora; (v) comparison of frequencies of use of linguistic metaphors in the twelve individual subcorpora. The significance levels of the frequency variations were calculated with the statistical test Log Likelihood. The results show that metaphor production increases at each proficiency level and varies according to the different text types: texts containing personal information in 3rd person tend to present higher frequency of metaphorical items when compared to personal narratives in 1st person, what corroborates findings from previous studies (BERBER SARDINHA, 2012).
Este trabalho re?ne referenciais te?ricos da Lingu?stica de Corpus e de correntes te?ricas da met?fora e tem o objetivo de verificar a varia??o na produ??o de met?foras por aprendizes brasileiros de ingl?s, atrav?s de uma abordagem baseada em corpus. O corpus utilizado na investiga??o foi o Brazilian English Leaner Corpus (BELC) (PACHECO, 2010), o qual ? composto por quatro n?veis de profici?ncia: (i) Beginner, (ii) Pre-Intermediate, (iii) Intermediate e (iv) Advanced; e tr?s tarefas: (i) tarefa 1 texto descritivo com informa??es pessoais em 1? pessoa, (ii) tarefa 2 texto descritivo com informa??es pessoais em 3? pessoa e (iii) tarefa 3 texto narrativo sobre uma viagem. O corpus foi anotado manualmente, com base nos procedimentos de Cameron (2003) e do Grupo Pragglejaz (2007). A frequ?ncia de met?foras foi extra?da com a ferramenta Concord do WordSmith Tools (SCOTT, 2012). A pesquisa foi organizada nas seguintes fases: (i) anota??o manual de met?foras no corpus; (ii) extra??o da frequ?ncia de met?foras no BELC e em seus subcorpora; (iii) compara??o das frequ?ncias de uso de met?foras lingu?sticas nos quatro subcorpora de n?veis de profici?ncia; (iv) compara??o das frequ?ncias de uso de met?foras lingu?sticas nos tr?s subcorpora de tipos textuais; (v) compara??o das frequ?ncias de uso de met?foras lingu?sticas nos doze subcorpora individuais. Os n?veis de signific?ncia das varia??es de frequ?ncia foram calculados com o teste estat?stico Log Likelihood. Os resultados mostram que a produ??o de met?foras aumenta em cada n?vel de profici?ncia e varia de acordo com tipos textuais diferentes: textos com informa??es pessoais em 3? pessoa tendem a apresentar frequ?ncia mais alta de itens metaf?ricos em compara??o com narrativas pessoais em 1? pessoa, o que corrobora resultados de estudos anteriores (BERBER SARDINHA, 2012).

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Zimmer, Stephan. "Charged Higgs Boson Studies in the Channel pp→a₁h^±→4b+l+MET in the Next-to MSSM (NMSSM) with the ATLAS Experiment." Thesis, Uppsala University, High Energy Physics, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-119324.

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Next-to-minimal super-symmetric extensions of the Standard Model (SM) predict the existence of several non-SM like Higgs bosons. The process pp→a₁h^±→4b+W involves the production and the decay of a spin-0 charged Higgs boson and a CP-odd Higgs boson a₁ which can have a sizable cross section in the NMSSM. The invariant masses of these intermediate bosons can be reconstructed from the four momenta of the final state particles using mass minimization algorithms. This thesis presents a cut-based analysis of two mass scenarios and specialized algorithms that are capable of recovering the signal in a large background arising from Standard Model processes such as ttbar. The analysis is tested with a realistic ATLAS detector simulation investigating trigger efficiencies and probing several jet reconstruction algorithms.

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Bedu, Clémence. "Quand une citadelle technique se (sou)met à l'épreuve de l'"impératif délibératif" : récit et analyse pragmatique d'une procédure de type "mini public" dans le domaine de l'eau potable." Strasbourg, 2010. https://tel.archives-ouvertes.fr/tel-00593368.

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Les procédures participatives et délibératives fondées sur le recours au citoyen profane connaissent un regain d’intérêt dans les démocraties actuelles, caractérisées par la remise en cause de la délégation de la décision à l’Elu et à l’Expert et par la montée en puissance des politiques de l’usager dans l’action publique locale. Ces expériences de « démocratisation de la démocratie » sont étudiées par un champ académique prolifique. A partir de l’analyse d’un projet de démocratisation de la vie d’un service d’eau potable d’une communauté urbaine mené dans le cadre d’une recherche-action, ce travail concentre l’attention sur certains angles délaissés dans la littérature : comment un projet de participation citoyenne est-il reçu et vécu en interne par une organisation qui le convoque ? Comment des citoyens profanes s’y prennent-ils pour penser et produire un avis dans le cadre d’une procédure de type « mini-public », et qu’est-ce qui contingente la trajectoire de cette production collective ? Comment une telle initiative de participation citoyenne impacte-t-elle ses protagonistes et le système d’action publique locale en l’absence de controverse et de « prise » de participation ? Pour décrire cette entreprise située de mise à l’épreuve de l’hypothèse de la démocratie technique, nous développons une approche inductive inspirée de la sociologie pragmatique. On s’efforcera de contribuer sur un plan théorique d’une part, à la description de l’activité délibérative, sur un plan opérationnel d’autre part, aux conditions d’efficacité et de prise au sérieux des démarches participatives de type « mini-public » au niveau local
Participative and deliberative procedures founded upon reliance on the average citizen are seeing an increasing relevance within today’s democracies, characterized by their challenging of the delegation of decision-making to the Representative and the Expert, and by the User’s rising political power in local politics. These instances of "democratising democratcy” have been studied extensively in the academic world. By starting with an analysis of a scheme to democratize drinking water provision within an urban community, conducted within the framework of action research, this study focuses on a few neglected points of view in academic writing: how is a participatory project for citizens received and experienced within an organization that originally requested their participation? How do regular citizens go about thinking and producing a collective report within a “mini-public” framework, and what influences the trajectory of this collective product? How does this initiative in citizen participation impact its protagonists and the local political system, in the absence of controversy? In order to test the hypothesis of technical democracy in detail, an inductive approach has been developed, inspired by pragmatic sociology. On the one hand this work will endeavor to contribute theoretically, by describing deliberative activity, and on the other, operationally, provided that local “mini-public” participative approaches are treated with seriousness and efficiency

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Silveira, Ericka Janine Dantas da. "Perfil imuno-histoqu?mico do infiltrado inflamat?rio no front de invas?o em carcicomas epiderm?ides de l?ngua e l?bio inferior." Universidade Federal do Rio Grande do Norte, 2007. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17168.

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The progression of the oral squamous cells carcinomas (OSCCs) seems to suffer influence from related factors to the host, as local and systemic immunologic response, which are essential to the antineoplasic defenses. The purpose of this study was evaluate the local immunity in 30 tongue and 20 lower lip SCC by immunohistochemistry method, utilizing antibodies anti-CD3, CD4, -CD8, -CD25 e -ζ(zeta), which immunoexpressions were compared considering the anatomical localization, the intensity of the inflammatory infiltrate into the front of invasion and metastases. The CD4/CD8+ ratio was calculated for each case and associate with the mentioned variable, being the intensity of the inflammatory infiltrated also compared with the anatomical localization and metastase and for this the cases had been grouped in two categories: (n = 10) absent/scarce inflammatory infiltrate; and (n = 40) moderate/intense infiltrate. Fisher?s exact test was performed (α= 0.05) and it was not observed any significant correlation between these groups with anatomical sites and metastases. With regard to the immunoexpression, the CD3+, CD4+, CD8+ and CD25+ cells count was higher in the lower lip SCCs while the anti-ζimmunomarcation was more evident in the non metastatic cases. Through the statistical analyses, it was verified that the CD3 exhibited positive-significant correlation with the inflammatory infiltrate (p = 0.023). Furthermore, antibodies against CD8 and CD25 cells were also significantly correlated with the inflammatory infiltrate (p = 0.002 and 0.030, respectively) and with the anatomical site (p = 0.004 and p = 0.004) mainly in the lower lip SCCs. CD4/CD8 ratio did not show significant association with metastase nor with anatomical localization. We conclude that the inflammatory infiltrated of the Bryne s (1998) system did not constitute an indicator of aggressiveness in the tongue and lower lip SCCs analyzed and that clinical behavior of the SCCs studied was related in part to the immunohistochemical profile of infiltrated the inflammatory present in tumoral invasion front
A progress?o dos carcinomas epiderm?ides orais (CEOs) parece sofrer influ?ncia de fatores relacionados ao hospedeiro, como a resposta imunol?gica local e sist?mica, as quais parecem ser essenciais para a defesa anti-neopl?sica. O presente estudo teve por objetivo analisar a imunidade local em 30 casos de CEs de l?ngua e 20 de l?bio inferior, atrav?s do m?todo da imuno-histoqu?mica, utilizando os anticorpos anti-CD3, -CD4, -CD8, -CD25 e -ζ(zeta), comparando a imunomarca??o em ambas as localiza??es, com a intensidade de infiltrado inflamat?rio no front de invas?o e com presen?a ou n?o de met?stase. A raz?o de c?lulas CD4/CD8+ foi calculada para cada caso e associada com as vari?veis mencionadas, sendo a intensidade do infiltrado inflamat?rio comparada tamb?m com a localiza??o anat?mica e met?stase e para isso os casos foram agrupados em duas categorias (infiltrado escasso ou ausente E/A e infiltrado intenso ou moderado I/M), sendo encontrado 10 casos na categoria E/A e 40 na categoria I/M. Aplicado o teste exato de Fisher n?o verificamos associa??o significativa destes grupos com o s?tio anat?mico ou com met?stase. Em rela??o ? imunomarca??o, a contagem das c?lulas CD3+, CD4+, CD8+ e CD25+ foi maior nos CEs de l?bio inferior e sem met?stase, enquanto que o anti-ζfoi mais expresso apenas nos casos sem met?stase. Atrav?s da an?lise estat?stica verificou-se que os anticorpos anti-CD3, anti-CD8 e anti-CD25 exibiram associa??o significativa positiva com o infiltrado inflamat?rio (p=0.023, p=0.002 e p=0.030, respectivamente); e os anticorpos anti-CD8 a anti-CD25 estiveram associados de forma positiva com a localiza??o anat?mica, ambos com valores de p=0.004, estando estes mais presentes nos CEs de l?bio inferior. A raz?o CD4/CD8 n?o exibiu associa??o significativa com met?stase nem com localiza??o anat?mica. Conclu?mos que o padr?o infiltrado inflamat?rio da grada??o histol?gica de malignidade de Bryne (1998) n?o constituiu um indicador de agressividade nos CEs de l?ngua e l?bio inferior analisados, e que o comportamento cl?nico dos CEs estudados esteve relacionado em parte ao perfil imuno-histoqu?mico do infiltrado inflamat?rio presente no front de invas?o tumoral

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Ma, Ying [Verfasser], Nediljko [Akademischer Betreuer] Budisa, Nediljko [Gutachter] Budisa, and Elke [Gutachter] Dittmann. "Metabolic engineering of O-acetyl-L-homoserine sulfhydrylase and Met-biosynthetic pathway in Escherichia coli : residue-specific chemoselective conjugation on azide functionalized proteins / Ying Ma ; Gutachter: Nediljko Budisa, Elke Dittmann ; Betreuer: Nediljko Budisa." Berlin : Technische Universität Berlin, 2017. http://d-nb.info/1156014034/34.

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Santoro, Alessia. "How I Met Your Mother: l'umorismo nel doppiaggio." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/7460/.

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Il presente lavoro ha come obiettivo quello di fornire informazioni generiche sul doppiaggio, comprendenti la sua nascita, il suo sviluppo e le tecniche adottare da traduttori, dialoghisti e adattatori che si occupano della traduzione audiovisiva. Partendo da questi aspetti generici, l’analisi si focalizzerà sulla traduzione per il doppiaggio, in particolare per quanto concerne gli aspetti umoristici e comici di serie televisive e film, prendendo come esempio più specifico la sitcom americana “How I Met Your Mother”. Lo studio si concentrerà su un confronto tra la versione originale americana in lingua inglese e la versione doppiata in italiano, individuando problemi legati alla traduzione, rese adeguate e, in alcuni casi, inadeguate. Nello specifico, nel primo capitolo si definiranno le fasi che hanno caratterizzato la storia del doppiaggio, dalla sua nascita al suo stato attuale. Successivamente si esporranno le tecniche di doppiaggio e le difficoltà che i traduttori inevitabilmente incontrano durante il processo di adattamento audiovisivo. Nel secondo capitolo, invece, si forniranno le definizioni di comicità e umorismo secondo diversi autori e fonti autorevoli, concentrandosi soprattutto sulle problematiche derivanti dalla non universalità dell’umorismo. Nella seconda parte del capitolo si analizzeranno più a fondo le tecniche del doppiaggio legate al mondo dell’umorismo e della comicità e le numerose problematiche derivanti dalla presenza di battute di spirito, giochi di parole e barzellette nella versione originale. Nel terzo e ultimo capitolo lo studio si focalizzerà sulla sitcom americana “How I Met Your Mother”, fornendone una breve trama e presentazione dei personaggi. L’analisi diverrà successivamente più dettagliata e riguarderà alcune espressioni comiche ricorrenti e dialoghi tratti dalla settima e ottava stagione della serie televisiva in questione, concentrandosi in particolare su quelle scene in cui entra in gioco l’umorismo e la loro resa nella lingua di arrivo, in questo caso l’italiano.

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Rodriguez, Jorge J. "The rape of the author how Charles Mee (re)defines authorship and its manifestation in his play Big Love /." Diss., Connect to the thesis, 2007. http://hdl.handle.net/10066/1024.

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Serra, Carlotta. "How the episode (hasn't quite) met its title: Analisi e proposta di traduzione dei titoli degli episodi della serie televisiva americana "How I met your mother"." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/7404/.

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Questo elaborato si concentra sulla serie televisiva americana How I met your mother e sulla traduzione italiana dei titoli degli episodi che la compongono. In particolare, si prederanno in esame quelle proposte traduttive che non rispettano appieno le regole che governano la tipologia testuale del titolo, e verranno proposte soluzioni alternative. In seguito, si analizzeranno alcuni dei titoli appartenenti alla stagione inedita in Italia, per i quali si proporranno delle traduzioni appropriate. Al fine di rendere più concreta questa analisi, una parte della tesi verrà anche dedicata agli aspetti teorici indicati da Maurizio Viezzi riguardo alla tipologia testuale del titolo. Inoltre, si parlerà anche delle varie funzioni individuate dalla studiosa di traduzione Christiane Nord che dovrebbero generalmente regolamentare la traduzione di questo tipo di testo.

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21

Nascimento, George Jo?o Ferreira do. "Associa??o entre polimorfismos funcionais nos genes da MMP-7 e MMP-9 e o perfil clinicopatol?gico do carcinoma epiderm?ide de l?ngua." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17145.

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Made available in DSpace on 2014-12-17T15:32:28Z (GMT). No. of bitstreams: 1 Tese_GeorgeJFN.pdf: 2720479 bytes, checksum: 6d72db8b12a0e5f743d69a67430d66b7 (MD5) Previous issue date: 2010-02-18
Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico
Matrix metalloproteinase-7 (MMP-7) and -9 (MMP-9) modulate important functions strictly related to the development, invasion and metastasis of several human cancers among them the squamous cell carcinoma of the tongue (SCCT). However, individual genetic factors such as the functional single nucleotide polymorphisms (SNPs) influence the pattern of protein expression of these MMPs and thus may be related to the variability observed in the clinical behavior of patients with SCCT. In this context, the present cross-sectional study aimed to evaluate the association between the frequency of the functional SNPs MMP-7 -181 A/G and MMP-9 -1562 C/T and the clinical (age, gender and metastasis) and pathological (malignancy histological grading and immunohistochemistry expression) features of SCCT cases. Genotyping of these SNPs were performed by PCR-RFLP on DNA samples from 71 cases of SCCT and 60 individuals without cancer who constitute the control group. Among the results of this research, it was observed that the frequency of the polymorphic alleles MMP-7 -181 G and MMP-9 -1562 T in SCCT patients was 28% and 12%, respectively, and the frequency of the heterozygotes A/G (PR = 2.00; p < 0.001) and C/T (PR = 1.54; p = 0.014) were significantly higher in the patient group than in the controls. The prevalence of patients carrying the combination of SNPs studied was significantly associated with SCCT cases (PR = 2.00; p = 0.011) and metastasis (PR = 2.00; p < 0.001). Furthermore, with the frequency of SNPs analyzed, the age, gender, histological grading and immunoreactivity of MMP-7 and MMP-9 formed clinical and pathological parameters relevant to the identification of population subgroups more related to the development of SCCT and metastasis. Based on these results, it is suggested that the protein expression levels of MMP-7 and -9 substantially influence the balance between their pro- and anticancer biological functions and hence the clinicopathological profile of the squamous cell carcinoma of the tongue
As metaloproteinases da matriz extracelular-7 (MMP-7) e -9 (MMP-9) modulam importantes fun??es relacionadas ao desenvolvimento, invas?o e met?stase de diversos c?nceres humanos, dentre os quais o carcinoma epiderm?ide de l?ngua (CEL). Entretanto, fatores gen?ticos individuais, tais como polimorfismos de nucleot?deo ?nico (SNPs) funcionais, influenciam no padr?o de express?o proteica dessas MMPs, podendo estar relacionados ? variabilidade no comportamento cl?nico tumoral observado em pacientes com CEL. Neste contexto, o presente trabalho objetivou, atrav?s de an?lise em sec??o transversal, estudar a associa??o entre a frequ?ncia dos SNPs funcionais MMP-7 -181 A/G e MMP-9 -1562 C/T e as caracter?sticas cl?nicas (idade, sexo e met?stase) e patol?gicas (grada??o histol?gica e express?o imuno-histoqu?mica) em uma s?rie de casos de CEL. A genotipagem dos referidos SNPs foi executada por PCR-RFLP em amostras de DNA de 71 casos de CEL e de 60 indiv?duos sem c?ncer, que constitu?ram o grupo controle. Dentre os resultados da presente pesquisa, evidenciou-se que a frequ?ncia dos alelos polim?rficos MMP-7 -181 G e MMP-9 -1562 T nos pacientes com CEL foi de 28% e 12%, respectivamente, sendo as frequ?ncias dos heterozigotos A/G (RP = 2.00; p < 0.001) e C/T (RP = 1.54; p = 0.014) significativamente maiores neste grupo de pacientes que no grupo controle. A preval?ncia dos pacientes portadores da combina??o dos SNPs estudados associou-se significativamente aos casos de CEL (RP = 2.00; p = 0.011) e ? met?stase (RP = 2.00; p < 0.001). Ademais, junto ? frequ?ncia dos SNPs analisados, a idade, sexo, grada??o histol?gica e imunoexpress?o da MMP-7 e -9 constitu?ram par?metros clinicopatol?gicos relevantes para a identifica??o de subgrupos populacionais mais predispostos ao desenvolvimento do CEL e met?stase. Frente a estes resultados, sugere-se que os n?veis de express?o da MMP-7 e -9 influenciam consideravelmente no balan?o entre suas fun??es pr? e antineopl?sicas e, consequentemente, no perfil clinicopatol?gico do carcinoma epiderm?ide de l?ngua.

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Soulas, Romain. "Effet de la cristallographie sur les premiers stades de l'oxydation des aciers austénitiques 316 L." Phd thesis, Université de Grenoble, 2012. http://tel.archives-ouvertes.fr/tel-00875564.

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Les conduites primaires des centrales nucléaires REP (304L et 316L) sont protégées contre la corrosion par une couche d'oxyde. Ces conduites, qui forment une barrière entre le milieu primaire et l'extérieur, subissent des phénomènes liés à la corrosion sous contrainte (assisté ou non par irradiation) pouvant entrainer des dommages. L'objectif de cette étude est de comprendre les phénomènes régissant les stades initiaux de formation des couches d'oxydes sur ces alliages en tenant compte de l'orientation cristallographique des grains sous-jacents. En utilisant des techniques de caractérisation avancées comme GIXRD, spectroscopie Raman, XPS, MEB et MET (BF, HRTEM, Astar, EELS et HREELS), sur les toutes premières étapes de l'oxydation, une séquence d'oxydation a été proposée pour l'alliage 316L.

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Juniel, Aude-Léa. "L' applicabilité des normes outre-mer." Montpellier 1, 2009. http://www.theses.fr/2009MON10042.

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De, Roubaix J. A. M. (John Addey Malcolm). "n Postmoderne uitdaging aan die 'paradigmale biomediese etiek model' met verwysing na kompleksiteitsteorie." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/52965.

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Thesis (MPhil)--University of Stellenbosch, 2002.
ENGLISH ABSTRACT: Introduction From the postmodern ethical perspective [the postmodernist would say Jrom the ethical perspective], there is something suspicious and inherently unethical in a system of ethics supported by a comprehensive, cohesive and universal metanarrative, a set of fixed and unbending ethical rules and laws, without the ready possibility of revision [Cilliers, 1998, pp.114, 137-140; Cilliers, 2001, p. 3; Cilliers, 1995, p.125]. Based on the ideas of especially Winkler [1993, pp. 343-365] I have concluded that contemporary mainstream biomedical ethics, represented and directed by the work of Beauchamp and Childress [1994] are caught in such a crush. The primary objective of this assignment is to evaluate the 'principles' of biomedical ethics [respect Jar autonomy, beneficence, non-maleficence and justice] which were developed in their water-shed publication [Principles of Biomedical Ethics, Oxford University Press, first published in 1979, and now in a fifth edition, 2002] against a background of postmodern ethics. Methodology and conclusions I have argued that Beauchamp and Childress' conception of principlism is a contextual legalistic-philosophical response to the contemporary American situation, developed primarily from legal decisions [often litigation]. It may be regarded as acceptable practice guidelines, but represents a system of ethics without morality. I have given a concise rendering of Winkler's notion of context-based bioethics with the criticism that this also does not guarantee morality. Following that, there is a description of postmodern society in terms of complexity theory. I have indicated how the characteristics of complexity can be developed and applied contextually in bioethics. The postmodern moral society is the locus where morality develops in a non-controllable agonistic interactive process within which the postmodern moral agent unintentionally finds himself. The postmodern ethical position is not an unethical, come-as-you-may anything-goes position; it simply is not predictable, controllable, universal, rational [in a Kantian context] and eternal. Modernity, it can be argued exhibits a far greater degree of relativism. The postmodern ethical position represents a return to morality in ethics, morality of a very personal, face-to-face responsibility from which we as participants of society cannot hide. From a postmodern ethical perspective, an analysis of principlism and its underlying principles exhibits the characteristics of modernity: eternal moral rules which as such cannot be presented as morality. I have acknowleged Beauchamp and Childress' attempts at adding morality to their conception [in the 4th edition] by means of employing character ethics. They have nevertheless not made any radical changes in the format of their presentation and maintain the central and primary role of principles. I have also argued the limitations of the postmodern approach in terms of enclaves of strictly controlled modernity and artificial witholding of information in medicine which limit the free flow of information essential to the postmodern approach. My conception of complexity and the postmodern approach do not pretend to be a panacea for biomedical ethics. It attempts to redefine the meaning of morality in bioethics and questions the unbridled application of this conception of principIism. Finally I have discussed the burning issue of justice in the practice of medicine from the postmodern perspective. Do I as a person have a right to health care; what are the moral issues of dealing with 'life's lotteries'; what is the state's responsibility in health care, and: what are my personal responsibilities in health care? In contradistinction to libertarian concepts, the postmodern approach clearly argues in favour of the acceptance by the state of its role in health care [a responsibility abrogated in many societies, none more so than contemporary South-African society].
AFRIKAANSE OPSOMMING: Inleiding Daar IS uit die perspektief van die postmoderne etiese standpunt [die postmodernis sou sê, uit die etiese perspektiej], iets verdags, iets inherent oneties aan 'n sisteem van etiek wat 'n enkele goed omskrewe, kohese en omvattende universele metanarratief voorhou, 'n stel vaste en onbuigsame etiese reëls en wette voorskryf en afdwing sonder om konteks en gevolge te oorweeg, en sonder die geredelike moontlikheid van revisie [Cilliers, 1998, pp.114, 137-140; Cilliers, 2001, p. 3; Cilliers, 1995, p.125]. Dit is, n.a.v. die denke van veral Winkler [1993, pp. 343-365] my oortuiging dat die hoofstroom-denke in biomediese etiek in so 'n drukgang vasgevang is, en verteenwoordig word en gerig is deur die denke van Beauchamp en Childress [1994]. Hierdie werkstuk gaan in hoofsaak daarom om Beauchamp en Childress se toepassing van die beginsels van biomediese etiek soos sedert 1979 in hul waterskeidingsboek 'Principles of Biomedical Ethics' [Vierde uitgawe, Oxford University Press, 1994; daar is nou ook 'n vyfde, 2002] uiteengesit, ontwikkel, bespreek en gepropageer [respek vir outonomie, weldadigheid, non-kwaadwilligheid en geregtigheid] teen die agtergrond van 'n postmoderne etiese beskouing te evalueer. Metodologie en gevolgtrekkings Ek het in hierdie werkstuk aangetoon dat Beauchamp en Childress se weergawe van prinsiplisme 'n kontekstuele wetlik-filosofiese reaksie op die kontemporêre Amerikaanse situasie is, hoofsaaklik uit regsaksie [dikwels litigasie] voortvloei, as goeie praktyksriglyne beredeneer kan word maar etiek sonder moraliteit verteenwoordig. Ek het 'n kort uiteensetting van Winkler se weergawe van 'n konteks-gebaseerde benadering gegee, maar aangetoon dat ook dit nie moraliteit waarborg nie. Daarop het ek 'n beskrywing van die postmoderne samelewing n.a.v. kompleksiteitsteorie gegee, en aangetoon hoe die eienskappe van kompleksiteit kontekstueelontwikkel kan word om in bioetiek toegepas te word. Die postmoderne gepostuleerde morele gemeenskap is die lokus waar moraliteit ontstaan deur 'n onbeheerbare agonistiese proses van interaktiewe wisselwerking waarby die postmoderne morele agent homself onwillekeurig betrokke vind. Die postmoderne etiese posisie is nie onetiese, lukraak, doen-soos-jy-wil relativisme nie; dit is bloot nie 'n voorspelbare, ewige, beheerbare, universele en [Kantiaans-] rasionele sisteem nie; moderniteit is [was?] in effek veel meer relativisties. Die postmoderne etiese standpunt verteenwoordig in my interpretasie 'n terugkeer tot moraliteit in etiek, moraliteit van 'n persoonlike, ingrypende, verantwoordelike aangesigtot- aangesig aard waaraan ons nie kan ontkom nie. Vanuit 'n postmoderne etiese perspektief het ek 'n analise van prinsiplisme en die individuele beginsels gemaak, en aangetoon dat hulle die eienskappe van die 'ewige morele reëls' van moderniteit openbaar en nie sonder meer as morele beredenering voorgehou kan word nie. Ek het erkenning gegee aan Beauchamp en Childress se eie pogings om dit te besweer deur karakteretiek as 'n essensiële tot hul formule toe te voeg, maar die kritiek uitgespreek dat hulle desnieteenstaande hierdie belangrike erkenning, nie bereid is om die formaat van hul aanbieding [ook in die jongste vyfde uitgawe, 2002] radikaal te wysig nie. Hulle oorbeklemtoon die beginsels steeds as sentraal en primêr. Terselfdertyd het ek die beperkings van die postmoderne benadering uitgelig, veral in terme van enklawes van streng-beheerde moderniteit in geneeskunde en 'n kunsmatige weerhouding van die vrye vloei van informasie wat kompleksiteit en die postmoderne situasie kenmerk. My konsepsie hou nie kompleksiteit en 'n postmoderne benadering voor as 'n panakeia vir biomediese etiek nie; dit dien eerder om die betekenis van moraliteit in bioetiek te herdefinieer en die kontemporêre algemene en ongekwalifseerde toepassing van hierdie weergawe van prinsiplisme te bevraagteken. Laastens het ek die brandende vraag van geregtigheid in die praktyk van geneeskunde vanuit 'n postmoderne perspektief bespreek, veral of ek as persoon kan aanspraak maak op 'n reg tot gesondheidsorg, die morele implikasies van 'life's lotteries', die staat se verantwoordelikheid in gesondheidsorg en les bes, persoonlike verantwoordelikheid in gesondheidsorg. Dit is duidelik dat 'n postmoderne benadering tot bioetiek, in teenstelling met libertêre konsepsies, die staat se rol in gesondheidsorg onderskryf ['n rol wat die staat byna universeel, en veral in Suid-Afrika, verwaarloos].

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Cardoso, Karen Franco de Godoi [UNESP]. "Qualidade do mel Apis mellifera L. produzido na região do Pólo Cuesta, Estado de São Paulo." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/104982.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Universidade Estadual Paulista (UNESP)
O objetivo deste trabalho foi caracterizar a qualidade higiênico-sanitária do mel produzido na região do Pólo Cuesta do Estado de São Paulo, por meio da enumeração do Número Mais Provável de Coliformes Totais e Termotolerantes, contagem de bolores e leveduras e atividade de água. Foram coletadas 37 amostras de méis de diferentes floradas produzidas por abelhas Apis mellifera L. em apiários distribuídos na região. As amostras de mel foram coletadas no momento do beneficiamento, acondicionadas em embalagens plásticas do apiário e armazenadas à temperatura ambiente. Todas as análises foram realizadas segundo as recomendações do Ministério da Agricultura, Pecuária e Abastecimento no Laboratório de Microbiologia de Alimentos do Instituto de Biociências da UNESP de Botucatu. Todas as amostras revelaram-se negativas quanto à presença de coliformes totais e termotolerantes e 34 (91,9%) apresentaram contaminação por bolores e leveduras, variando entre 102 até 105 UFC/g. Quanto a atividade de água, os menores valores foram observados na florada de laranja com média de 0,575±0,01 Aa, diferindo significativamente das floradas de eucalipto (0,629±0,02 Aa) e silvestre (0,614±0,02 Aa). Conclui-se que a qualidade microbiológica do mel produzido na região do Pólo Cuesta do Estado de São Paulo apresenta-se satisfatória
The objective of this study was to characterize the hygienic quality of the honey produced in the Pólo Cuesta region of São Paulo state by enumerating the Most Probable Number of Total Coliforms and Thermotolerants, by counting yeasts and molds, and by water activity. Thirty-seven samples of honey of flowerings produced by Apis mellifera L. bees in apiaries spread throughout the region were collected. The 28 honey samples were collected at processing, kept in plastic packages of the apiary, and stored in room temperature. All the analyses were carried out according to the recommendations of the Ministry of Agriculture, Livestock and Supply in the Laboratory of Food Microbiology of the Bioscience Institute at UNESP - Botucatu. All the samples proved negative as to the presence of total coliforms and thermotolerants and 34 (91.9%) of them presented some contamination by yeasts and molds ranging from 102 to 105 UFC/g. As to water activity, the lowest values were observed in the orange flowering with an average of 0.575±0.01 Aa, which is significantly different from the eucalyptus flowering (0.629±0.02 Aa) and from the sylvestral one (0.614±0.02 Aa). It is concluded that the microbiological quality of the honey produced in the Pólo Cuesta region of São Paulo state proves satisfactory

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Pluhař, Tomáš. "Návrh repliky letounu L-40 "Meta Sokol" - křídlo." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2008. http://www.nusl.cz/ntk/nusl-227918.

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This diploma thesis targets in concept of wing, aileron, flap and main undercarriage of the ultralight replication of the plane L-40 called Meta Sokol. The thesis developed from cooperation with two other members of the team – Alice Lipková (aerodynamics, power) and Miroslav Růžička (fuselage, tail unit and rear gear). The first part of this diploma thesis is concerned with load and concept of structure of the wing. At first the flight envelope is specified, then charakteristics of shearing force, bending moment and torsion moment are determined spanwise. The concept and subsequent strength verification of structure of the wing is also solved. The same process is claimed to concept of the aileron and the flap. The second part of this diploma thesis is dealt with main landing gear, its support, structure, springing and the principle of retraction. The final passage is devoted to load of the undercarriage.

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Růžička, Miroslav. "Návrh repliky letounu L-40 "Meta Sokol" - trup." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2008. http://www.nusl.cz/ntk/nusl-227921.

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This diploma thesis deals with the design of all-metal construction of fuselage of the replica L-40 Meta Sokol aircraft on the basis of CS-VLA regulation. As far as the aircraft is concerned, the thesis establishes the load of tail surfaces, landing gear and engine bed. Futhermore, it designs the construction of fuselage, tail landing gear, including the system of its retraction, wing-fuselage connection, engine bed and the primary design of cockpit. In the end, the thesis focuses on the fuselage production technology.

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Ciuchendea-Dobrei, Mihaela Andreea [Verfasser], Anca-Ligia [Akademischer Betreuer] Grosu, Michael [Akademischer Betreuer] Molls, and Andreas K. [Akademischer Betreuer] Buck. "Radiochirurgie und stereotaktisch fraktionierte Strahlentherapie am Linearbeschleuniger bei Patienten mit Meningeomen : Wertigkeit der L-[Methyl-11 C] Methionin (MET)-PET-Untersuchung als Ergänzung zu morphologischen bildgebenden Verfahren wie CT und MRT bei der Erstellung der Therapieplanung und Definition des Zielvolumens der Schädelbasismeningeome / Mihaela-Andreea Ciuchendea-Dobrei. Gutachter: Andreas K. Buck. Betreuer: Anca-Ligia Grosu ; Michael Molls." München : Universitätsbibliothek der TU München, 2011. http://d-nb.info/1019589698/34.

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Andersson, Hans. "Kunst lämnar huvudstaden : Ett möte med L. Dobyčins författarskap." Thesis, Stockholm University, Department of Slavic Languages, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-41826.

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Omarjee, Ismaël. "L' outre-mer franc̜ais et le droit social communautaire /." Paris : Librairie Générale de Droit et de Jurisprudence, 2000. http://www.gbv.de/dms/spk/sbb/recht/toc/323773028.pdf.

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Enochsson, Arvid. "Tolkning och rendering av L-system med beräknings-shaders." Thesis, Högskolan i Skövde, Institutionen för informationsteknologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-18762.

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I detta arbete utförs en jämförelse av exekveringstid för tolkning och rendering av Lindenmayersystem (L-system), utfört av samma algoritm på CPU’n (eng. central processingunit) och GPU’n (eng. graphics processing unit). Undersökningen fokuserar på exekveringstid och dess utveckling vid olika typer av L-system, längder samt upplösning. Algoritmen implementerades i spelmotorn Unity både på CPU’n via C# och på GPU’n medhjälp av beräknings-shaders. Experimenten bestod av två L-system. Ett med förgreningaroch ett utan. Båda L-systemen testades med olika upplösningar och längder, varpå exekveringstid avlästes. Experimentens resultat påvisar stor fördel hos CPU-lösningen gällande exekveringstid. Bristen på GPU-anpassad kod, exempelvis kod utan förgreningar och med bra minneshantering, leder till att GPU’n presterar sämre. Arbetet avslutas med förslag på vidareforskning. Förslagen innefattar utökad testning på olika hårdvara, en mer kontrollerad testmiljö samt implementering av algoritmen i faktisk spelproduktion.

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Sena, Suzara Rayanne de Castro. "Equil?brio l?quido-l?quido para o sistema biodiesel de ?leo de semente de mel?o (Cucumis melo l.) + metanol + glicerina." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br:8080/jspui/handle/123456789/15860.

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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
Rio Grande do Norte, northeast state from Brazil, it is the greatest producer and exporter of yellow melon, well known as Spanish melon. Despite the consumption of this fruit to be mainly its pulp, melon seeds are an important source of lipids considered an industrial residue it has been discharge product. The use of oilseeds in order to produce biodiesel establishes an important raw material and the increase of its production promotes the national development of the agriculture. In this background, the aim of this work has been to use oil from seeds of yellow melon to produce biodiesel and to accomplish a study of the phase equilibrium of the system evolving biodiesel, methanol and glycerin. The biodiesel was obtained by oil transesterification through methylic route with molar ratio 1:9.7 (oil:alcohol) and with a mass of NaOH of 0.5% from the oil mass; the reaction time was 73 minutes at 55 ?C. A yield of 84.94% in biodiesel was achieved. The equilibria data present a well-characterized behavior with a great region of two phases. The tie lines indicate that methanol has a best solubility in the phase that is rich in glycerin. Consistency of the experimental data was made based on Othmer-Tobias and Hand correlations which values above 0.99 were found to correlation coefficients, this fact confers a good thermodynamic consistency to the experimental data. NRTL and UNIQUAC models were employed to predict liquid-liquid equilibrium of this system. It was observed a better concordance of the results when NRTL was applied (standard deviation 1.25%) although the UNIQUAC model has presented a quite satisfactory result either (standard deviation 2.70%). The NRTL and UNIQUAC models were also used to evaluate the effect of temperature in the range of 328 K to 358 K, in which a little change in solubility with respect to the data obtained at 298 K was observed, thus being considered negligible the effect of temperature
O Rio Grande do Norte, estado da regi?o Nordeste do Brasil, corresponde ao maior produtor e exportador do mel?o amarelo, tamb?m conhecido como mel?o espanhol. Apesar do consumo dessa fruta ser basicamente a polpa, a semente do mel?o ? uma importante fonte de lip?dios, sendo considerada res?duo industrial tem sido produto de descarte. O uso de sementes oleaginosas como fonte para a produ??o de biodiesel constitui-se numa importante mat?ria-prima e o incentivo da sua produ??o contribui para o desenvolvimento agr?rio da na??o. Nesse sentido, o objetivo desse trabalho foi utilizar ?leo de semente de mel?o amarelo para produzir biodiesel e realizar um estudo de equil?brio de fases do sistema envolvendo biodiesel, metanol e glicerina. O biodiesel foi obtido pela transesterifica??o do ?leo atrav?s da rota met?lica na raz?o molar 1:9,7 (?leo:?lcool), usando uma massa de NaOH de 0,5% da massa de ?leo; o tempo de rea??o foi de 73 minutos a 328 K. Obteve-se uma taxa de convers?o de 84,94 % em biodiesel. Os dados de equil?brio apresentaram um comportamento bem caracterizado, com uma grande regi?o de duas fases. As linhas de amarra??o indicaram o metanol com uma solubilidade maior na fase rica em glicerina. A consist?ncia dos dados experimentais foi feita com base nas correla??es de Othmer-Tobias e Hand em que foram obtidos valores acima de 0,99 para os ?ndices de correla??o, conferindo uma boa consist?ncia termodin?mica aos dados experimentais. Os modelos NRTL e UNIQUAC foram utilizados para predizer o equil?brio l?quido-l?quido desse sistema, sendo observado uma melhor concord?ncia nos resultados quando NRTL foi empregado (desvio m?dio de 1,25%), embora o modelo UNIQUAC tamb?m tenha apresentado resultado bastante satisfat?rio (desvio m?dio de 2,70%). Os modelos NRTL e UNIQUAC ainda foram utilizados para avaliar o efeito da temperatura no intervalo de 328 K e 358 K, em que foi observada pouca varia??o na solubilidade em rela??o aos dados obtidos a 298 K, sendo assim considerado desprez?vel o efeito da temperatura

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33

Albino, Ivone Braga. "Constru??o de sentidos em l?ngua brasileira de sinais (libras): uma an?lise contrastiva entre falantes surdos e falantes ouvintes." PROGRAMA DE P?S-GRADUA??O EM ESTUDOS DA LINGUAGEM, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/24925.

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Esta tese tem como objetivo investigar o modo como surdos falantes de L?ngua Brasileira de Sinais (Libras) constroem sentidos, tomando por base a Lingu?stica Cognitiva e, dentro desse campo, a Teoria Neural da Linguagem. Em conson?ncia com os pressupostos te?ricos, utilizamos as no??es de categoriza??o (LAKOFF, 1987; DUQUE, 2001, 2002); de corporalidade (LAKOFF e JOHNSON, 1999; DUQUE e COSTA, 2011, 2012; BERGEN, 2008); e de narrativa (DUQUE, 2012; LAKOFF, 2008). Al?m disso, apresentamos categorias anal?ticas como esquemas-I (LAKOFF, 1987; JOHNSON, 1987); esquemas-X (FELDMAN, 2006); frames (FILLMORE, 1976, 1982; DUQUE, 2015); met?foras conceptuais e meton?mia (LAKOFF e JOHNSON, 1999, 1980, 2002; GIBBS, 1994, 1999, 2005) em Libras. A tese defendida ? a de que a constru??o de sentidos em narrativas por falantes surdos de Libras est? atrelada a processos cognitivos relacionados a a??es e percep??es no mundo. Desse modo, a linguagem n?o est? dissociada de processos criadores, que refletem, portanto, os processos gerais do pensamento elaborados pelos indiv?duos quando criam seus significados e os adaptam a contextos diferentes de intera??o com outros indiv?duos. O corpus utilizado na pesquisa ? constitu?do por v?deos de falantes surdos de Libras (grupo experimental) e de falantes ouvintes de Libras (grupo de controle); o estudo ? de natureza qualitativa, pautado na metodologia emp?rica quase-experimental (MONTERO; LEON, 2007). As an?lises de dados apontam para a exist?ncia de padr?es referentes ao modo particular a partir do qual os surdos falantes de Libras compreendem suas rela??es com o mundo e conceitos espec?ficos, cognitivamente constru?dos, utilizando a l?ngua visuomotora. A ativa??o de circuitos neurais corrobora as hip?teses de que os surdos falantes de Libras exploram mais o campo visual; agregam outros aspectos perceptuais relacionados ? forma e ao movimento dos objetos (ordena??o espacial, foco e aten??o); os indexadores lingu?sticos (sinais) acionam esquemas-I e esquemas-X, frames; e o pr?prio sinal tem base metaf?rica e/ou meton?mica. A vertente de an?lise cr?tica acerca do modo como ocorrem cognitivamente os sinais em seus falantes sugere que, no ensino de Libras, sejam considerados os mecanismos de ativa??o de processos cognitivos durante a sinaliza??o da l?ngua, cujas experi?ncias se efetivam em ambiente n?o-auditivo.
This thesis aims to investigate how deaf Brazilian Language Signals? (Libras) speakers construct meanings, basing on Cognitive Linguistic, particularly Language Neural Theory. According to the theoretical assumptions, this study uses categorization notions (LAKOFF, 1987; DUQUE, 2001, 2002); corporality (LAKOFF; JOHNSON, 1999; DUQUE; COSTA, 2011, 2012; BERGEN, 2008); and narrative (DUQUE, 2012; LAKOFF, 2008). In addition to this, it presents analytical categories as schemes-I (LAKOFF, 1987; JOHNSON, 1987); schemes-X (FELDMAN, 2006); frames (FILLMORE, 1976, 1982; DUQUE, 2015); Libras conceptual metaphors and metonymy (LAKOFF; JOHNSON, 1999, 1980, 2002; GIBBS, 1994, 1999, 2005). This thesis confirms sense meaning in narratives of the deaf Libras? speakers links cognitive processes related to actions and perceptions in the world. In this sense, language is not apart from creator?s processes that reflect general thinking individual processes when they create their meanings and they adapt different interaction contexts with other subjects. This research has as corpus videos with deaf Libras? speakers (experimental group) and deaf Libras? listeners (control group), this study has a qualitative nature, with empirical methodology quasi-experimental (MONTERO; LEON, 2007). Data analyses point to the existence of models related to a particular way that deaf Libras? speakers understand their relationships with the world and with specific concepts, cognitively built, using visual motor language. Neural circuity activation collaborates to the hypothesis that deaf Libras? speakers explore visual field; they add other conceptual aspects related to the form and movement of the objects (spatial order, focus and attention); linguistic index (signals) that activate schemes-I and schemes-X, frames, and the signal that has a metaphorical and/or metonymical base. The critical analyze about the occurrences of cognitive signal by the speakers suggests Libras teaching must considerate cognitive processes activation mechanisms during language signalization, whose experiences appear in a not hearing space.

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34

MELO, Zilmar Fernandes Nóbrega. "Características físico-químicas de méis de abelha (Apis mellifera L.) em diferentes condições de armazenamento." Universidade Federal de Campina Grande, 2002. http://dspace.sti.ufcg.edu.br:8080/jspui/handle/riufcg/901.

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Estudou-se o armazenamento de méis de abelhas africanizadas (Apis mellifera L.) coletados no brejo e cariri do estado da Paraíba. Utilizou-se, quanto à florada, dois tipos de mel de abelha (mel de florada silvestre e mel de florada de baraúna), armazenados sob 3 diferentes condições de embalagens (El - recipiente de polietileno opaco e exposto à luz e temperatura ambiente; E2 - recipiente de polietileno exposto à temperatura ambiente e ao abrigo da luz; E3 - recipiente em vidro translúcido exposto à temperatura e luz ambiente), ao longo de 180 dias, tendo sido estes submetidos a análises físico-químicas mensalmente, com a finalidade de observar as possíveis alterações nas características físico-químicas (°Brix, Umidade, Cinzas, Hidroximetilfurfural-HMF, Açúcares redutores, Sacarose aparente, Atividade diastásica e pH), objetivando verificar a eficiência destas embalagens no índice de qualidade dos méis. As análises físico-químicas dos méis foram feitas seguindo o recomendado pela Instrução Normativa do Ministério da Agricultura e do Abastecimento (Brasil, 2000). Os valores médios encontrados, ao longo do Armazenamento, para o °Brix do mel silvestre ficaram no intervalo de variação de 78,03 a 78,42 °Brix e o da florada de baraúna de 81,31 a 81,63 °Brix e não houve diferença significativa entre as embalagens ao longo do armazenamento. Os níveis de Umidade (%) para os méis silvestres e de baraúna foram 19,48 a 20,48 % e 16,25 a 16,70 %, respectivamente. Os valores Cinzas e de Sólidos Insolúveis não apresentara diferenças significativas no tempo e/ou nas embalagens. Os níveis no índice de HMF ficaram no intervalo de variação de 4,57 a 10,17 mg/kg de mel e 1,08 a 7,12 mg/kg, no mel Silvestre e no mel de baraúna, respectivamente. Pelas análises estatísticas, verificou-se, para os dois méis, diferença significativa a 1% de probabilidade e que as médias diferem entre si. Houve para o HMF, diferença significativa entre as embalagens e a E2 foi a mais eficiente no controle do aumento deste índice nos dois méis estudados. Os valores médios de Açúcares Redutores ficaram entre 74,09 e 76,41 % no mel Sivestre e entre 62,51 e 64,80 % para o mel de baraúna. Os valores de Sacarose Aparente ficaram entre 2,18 a 3,01 % para o mel silvestre e entre 2,40 e 2,89 % no mel de baraúna. Os méis sofreram pequena variação no tempo e as embalagens não influenciaram sobre a sacarose, nos dois méis. A Atividade Diastásica (DN) no mel Sivestre ficou no intervalo de variação de 13,37 a 18,71 DN e 9,14 a 13,25 DN no mel de baraúna. As análises estatísticas para os dois méis foram significativas ao nível de 1% de probabilidade e no teste de Tukey, as médias diferiram entre si, e a embalagem E2, nos dois méis analisados, mostrou-se mais eficiente na desaceleração do índice de Diástase em relação a El e E3. Quanto ao pH, o mel Sivestre foi mais ácido (3,42 a 3,55) do que o mel de baraúna (3,85 a 4,15). Todas as amostras encontram-se dentro dos padrões exigidos pelo Ministério da Agricultura e do Abastecimento. Do resultado final, concluiu-se que houve maior eficiência na embalagem E2, que contribuiu para a desaceleração do ritmo no índice de diástase. Observou-se que o índice de acidez livre aumentou ao longo do armazenamento.
The storage of african bees honeys (Aipis mellifera L.) which were collected from slough and cariri in Paraíba state was studied. Considering the bloomed, two kinds of bee honey (wild bloomed honey and baraúna bloomed honey) were used and storaged under three different conditions of packages ( Ei - opaque polyethylene container, that was under environment light and temperature; E2 - polyethylene container that was under environment temperature but it wasn't under light environment; E3 - translucent glass container which was exposed to environment temperature and light). These honeys stayed 180 days in packages and their physiochemical characteristics were analysed monthly to observe the possible alterations of them ( 0 Brix, Humidity, Ashes, Hydroximethylfurfurol - HMF, Reducers Sugar, Apparent Saccharose, Diastasic Activity and pH) to verify the efficiency of these packages in the honeys qualities index. The physiochemical analyses of the honeys were done according to the Normative Instruction of the Agriculture and Provisioning Ministry (Brazil, 2000). During the storage time, the médium found values to the 0 Brix of the wild bloomed honey were between 78.03 and 78.42 0 Brix and the ones of the baraúna bloomed honey were between 81.31 and 81.63 0 Brix and there wasn't significant difference among the packages during the storage period. The Humidity rates (%) were between 19.48 and 20.48% to the wild honey and between 16.25 and 16.70 to the baraúna honey. There were no significant differences of the Ashes and Insoluble Solids values on their time and packages. The rates in the HMF index varied from 4.57 to 10.17 mg/Kg of honey and from 1.08 to 7.12 mg/Kg, to the wild and baraúna honeys, respectively. According to the statistics analyses, a significant difference of 1% of probability for both honeys was verified, besides the averages are different among them. To the HMF, there was a significant difference among the packages and the E2 was the most efficient to the control of the increase of this index in both studied honeys. The médium values of the Reducers Sugar were between 74.09 and 76.41% to the wild honey and they were between 62.51 and 64.80% to the baraúna honey. The Apparent Saccharose values were between 2.18 and 3.01% to the wild honey and they were between 2.40 and 2.89 to de baraúna honey. The honeys had a little time variation and the packages had no influence on the saccharose, in both honeys. The Diastasic Activity (DN) on the Wild honey varied from 13.37 to 18.71 DN and the variation of the baraúna honey was from 9.14 to 13.25 DN. The statistics analyses were significative at 1% of probability and at the Tukey test for both honeys, the averages were diferent among them and the E2 package was more efficient than the Ei and E3 to the unacceleration of the diástase index for both honeys. Analysing the pH, the wild honey was more acid (3.42 to 3.55) than the baraúna honey (3.85 to 4.15). Ali the samples are according to the Agriculture and Provision Ministry patterns. According to the final result, it's conclued that there was a bigger efficiency of the E2 package and it contributed to the rhythm unaceleration in the distasic index. It was observed that the free acidity index increased during the storage period.

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35

Lipková, Alica. "Návrh repliky letounu L-40 "Meta Sokol" - základní rozměry - technologie." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2008. http://www.nusl.cz/ntk/nusl-227920.

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The object of the diploma thesis is a preparation of fundamentals for realization for replica of the aircraft L-40 „Meta Sokol“ matching the requirements of Certification Specification for Very Light Aeroplanes (CS-VLA). The preamble of the work deals with the changes made on the original aircraft necessary to satisfy the criterias of the above-mentioned specification. One of the main contents of the first part of the thesis is the definition of replica’s basic dimensions and preparation of aerostatic fundamentals, including longitudinal stability control. As next a suitable engine is chosen and calculation of corresponding performances is made. A detailed weight analysis and a determination of centre of gravity position (c.g. position), important for solving the stability of an airplane, is also presented. Finally, a brief description of the manufacturing process of individual components and also factors influencing the technology are discussed.

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36

Lima, H?rik Dantas de. "Estudo de um comp?sito Nb-15%pCu obtidos por moagem de alta energia e sinterizados por fase l?quida." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br/handle/123456789/19594.

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Existe uma grande dificuldade na forma??o de um comp?sito do metal refrat?rio de ni?bio com o cobre. Isto se deve ao fato de que o sistema Nb-Cu ? quase mutuamente imisc?vel, podendo ser desprezada a solubilidade entre eles. Estas propriedades dificultam ou impedem a obten??o de estruturas homog?neas e de alta densidade, convencionalmente preparadas. Este trabalho tem por objetivo analisar a utiliza??o do processo de moagem de alta energia (MAE) para transpor estas dificuldades naturais, no que se refere ? densifica??o dos corpos sinterizados. A MAE e a prensagem foram utilizadas na prepara??o dos p?s, para a obten??o de uma fina e homog?nea distribui??o do tamanho dos gr?os. Quatro cargas de p?s de Nb e Cu contendo 15% em massa de Cu foram ent?o mo?dos por MAE em um moinho de bolas tipo planet?rio, sob diferentes per?odos e velocidades de moagem. Os resultados obtidos pela MAE foram analisados atrav?s da microscopia eletr?nica de varredura (MEV), de acordo com os par?metros de tempo e velocidade de moagem. As amostras foram compactadas sob press?o de 200 MPa, em seguida foram sinterizadas por fase l?quida em um forno ? v?cuo nas temperaturas de 1100?C/60 min e 1200?C/60 min. Depois foi utilizada a t?cnica de caracteriza??o de difra??o de raios-X para a identifica??o das fases. As microestruturas das amostras sinterizadas foram observadas e avaliadas atrav?s de microscopia eletr?nica de varredura (MEV). Ensaios de Microdureza Vickers foram realizados, obtendo maiores valores para os corpos sinterizados nos maiores tempos de moagem dos p?s e para as maiores velocidades de moagem. Foi verificado que a sinteriza??o por fase l?quida das amostras que foram processadas por MAE, produziu no final uma estrutura homog?nea e densificada em 77,4% em rela??o ao valor da densidade te?rica do comp?sito
There is great difficulty in forming a composite refractory metal niobium with copper. This is due to the fact that Nb-Cu system is almost mutually immiscible and may be neglected solubility between them. These properties hinder or prevent obtaining homogeneous and high-density structures, conventionally prepared. This study aims to analyze the use of high-energy milling process (MAE) to implement these natural difficulties, with regard to the densification of the sintered bodies. The MAE and the press were used in the preparation of powders, to obtain a fine and homogeneous distribution of the grain size. Four loads Nb and Cu powders containing 15% by weight of Cu were then milled for MAE in a planetary type ball mill under various milling times and speeds. The results obtained by MAE were analyzed by scanning electron microscopy (SEM), according to the parameters of time and grinding speed. The samples were compacted under pressure of 200 MPa, were then sintered in liquid phase in a vacuum furnace at temperatures of 1100 ? C / 60 min and 1200 ? C / 60 min. Then it was used to characterize diffraction of X-rays to identify the phases. The microstructures of the sintered samples were observed and evaluated using scanning electron microscopy (SEM). Vickers Microhardness tests were performed, obtaining higher values for the sintered bodies in the largest of the post milling times and the larger grinding speeds. It was found that the liquid phase sintering of the samples that were processed by MAE produced at the end of a homogeneous and densified structure in 77,4% relative to the value of the theoretical density of the composite

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37

Teixeira, Cristiane Cardoso Correia. "Desenvolvimento tecnológico de fitoterápico a partir de rizomas de Curcuma longa L. e avaliação das atividades antioxidante, anti-inflamatória e antitumoral." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-11012010-204508/.

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Este trabalho visou obter extratos secos padronizados de Curcuma longa L., e sua otimização visando o aumento da solubilidade dos curcuminóides e melhoria nas suas atividades biológicas. No estudo de extração, os curcuminóides foram extraídas utilizando dois solventes, etanol e solução etanólica alcalina e dois processos microondas e ultrassom seguindo planejamentos fatoriais completos 24, e com pH do solvente, teor de etanol, tempo de extração, potência do microondas ou temperatura no ultrassom, e proporção massa da droga pela massa do solvente como variáveis independentes. Os extratos foram caracterizados quanto ao rendimento de sólidos totais, teor de curcuminóides totais, rendimento de curcuminóides totais, teor de curcumina, rendimento de curcumina e atividade antioxidante por difenil-picril-hidrazila. A condição de extração com melhor resultado foi o ultrassom a 20 ºC, solvente etanol 96 ºGL, 1 parte de planta para 7 de solvente, pH 10 e duração de 5 min., pois, nesta condição, obteve-se maior teor de curcumina e maior atividade antioxidante. O estudo visando aumento da solubilidade da curcumina constou da preparação de dispersões sólidas pelos métodos de spray drying e hot melt coating. Ambos os métodos foram estudados com os polímeros hidrofílicos Gelucire® 44:14 e 50:13, e aplicando-se planejamento fatorial tipo Box-Behnken. As dispersões sólidas particuladas foram avaliadas pela morfologia, densidade aparente e de compactação, fator de Hausner, índice de Carr, ângulo de repouso, umidade residual, atividade de água, calorimetria diferencial de varredura, termogravimetria, difração de raio-X, espectrometria de infravermelho, solubilidade em água e teste de dissolução. A maior solubilidade foi obtida com secagem no spray drying a 40 ºC, proporção Gelucire®44/14:curcumina 1:1 e proporção 1:5 de Aerosil:dispersão (DS16). No hot melt coating, a melhor solubilidade foi obtida com maior quantidade de Gelucire 50/13 e menor de Lactose (DS 3). Dispersões sólidas particuladas foram preparadas também com o Gelucire® 50/13 por spray drying (DS 17). Considerando-se os fatores solubilidade e teor de curcumina nas partículas, a dispersão DS 17 foi escolhida como a mais adequada para os ensaios biológicos posteriores. A mesma condição de preparo da DS17 foi usada para produzir dispersões sólidas com o extrato obtido por ultrassom (DSE). Nesta dispersão a solubilidade dos curcuminóides demonstrou ser 330 vezes maior do que o extrato seco nas mesmas condições porém sem a adição de carreador. No ensaio de avaliação da atividade antitumoral in vitro, foram avaliadas a citotoxicidade da curcumina pura, DS 17, DS 3 e a DSE, em diferentes linhagens tumorais, leucemia T (jurkat), melanona (C8161), adenocarcinoma coloretal (HT29), carcinoma hepatocelular (HepG2) e de célula não tumoral (PBMC). A curcumina apresentou atividade citotóxica para células tumorais e esta não foi afetada pelo processo de produção da dispersão sólida. Além disso, a DS do extrato apresentou maior citotoxicidade, o que pode ser devido ao sinergismo de outros compostos. O extrato também foi mais seletivo para células tumorais que a curcumina e as dispersões. O estudo de atividade anti-inflamatória in vivo usando o modelo de edema de pata, demonstrou que a dispersão DS 17 apresentou maior atividade do que a curcumina na mesma dose, indicando que o aumento da solubilidade possibilita uma maior absorção e consequentemente maior biodisponibilidade.
The aim of this work was to obtain standardized dried extracts of Curcuma longa L. and to develop pre-formulations and capsules with improved curcuminoids solubility and higher biological activities. In the extraction study, the powdered roots of Curcuma longa L. were extracted using ethanol and an aqueous alkaline ethanol solution by microwave and ultrasound assisted methods, together with the application of 24 full factorial designs of experiments to better understand the effects of solvent pH, ethanol concentration, microwave power, ultrasound temperature and ratio of drug to solvent (w/w) on the extract. The extracts were characterized by solids yield, curcuminoid content and yield, curcumin content and yield and antioxidant activity by the diphenylpycril hydrazil method. The best extraction resulted from the ultrasound assisted using ethanol 96 oGL at pH 10, 20oC, 1:7 drug to solvent ratio (w/w), during 5 minutes. This condition was chosen because it resulted in the best yields and antioxidant activities. The work developed to improve curcumin and curcuminoid solubilities was based on the preparation of solid dispersions by spray drying and hot melt coating using the hydrophilic carriers Gelucire® 44:14 and 50:13. Applying Box-Behnken designs the effect of process conditions on microparticulate solid dispersions properties, like morphology, bulk and tapped densities, Hausner factor, Carr index, angle of repose, moisture content, water activity, differential scanning calorimetry, thermogravimetric analysis, X-ray powder diffraction, infrared spectrometry, curcuminoid solubility in water and dissolution rate. The highest improvement in drug solubility was obtained by dispersion prepared by spray drying at 40oC, Gelucire® 44:14/curcumin 1:1 ratio, and adding 16,7% Aerosil (DS16). On the other hand, the hot melt granules with best solubility were prepared with higher Gelucire® 50:13 and lower substrate (lactose) contents (DS3). Additional solid dispersion, DS17, was prepared by spray-drying in the same conditions applied to DS16 but using Gelucire® 50:13 as carrier. Considering the aspects drug solubility and content in solid dispersions, DS17 showed the best performance and the same set of conditions used for its preparation was also applied to produce a solid dispersion containing the raw extract obtained by ultrasound extraction. This solid dispersion increased curcumin solubility by a 330-fold factor. In the in vitro antitumor assays pure curcumin, DS3, DS17 and DSE cytotoxicities were evaluated in several tumor cell lines, leukemia T (jurkat), melanona (C8161), adenocarcinoma coloretal (HT29), hepatic carcinoma (HepG2) and in one non tumor (PBMC). The antitumor activities were not influenced by the thermal processes and the extract presented higher cytotoxicity and better selectivity to tumor cells. The in vivo antinflammatory study was performed by the rat paw edema method and showed that solid dispersion DS17 resulted in antinflammatory effect higher than pure curcumin and indomethacin at some doses. The results are an indicative that the increase in drug solubility may incur in an increase oral bioavailability and that the process proposed herein are adequate for preparation of pre-formulations containing less soluble herbal drugs.

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Farris, Charles Adron. "Charles Mee's Hotel Cassiopeia a directorial composition in search of the 'inner life' /." Oxford, Ohio : Miami University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1247861560.

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39

Inácio, Estela Maris. "Impactos da deriva do herbicida 2,4-D em culturas sensíveis." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/11/11136/tde-30092016-105412/.

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O herbicida 2,4-D é utilizado principalmente para o controle de plantas daninhas em condições de pós-emergência em culturas em que o herbicida é seletivo, bem como no manejo da vegetação em pré-plantio; no entanto, devido a suas características físico-químicas, pode ocasionar danos às culturas vizinhas sensíveis, através dos fenômenos de deriva da molécula durante as pulverizações. Sendo assim, é de fundamental importância o conhecimento técnico dos impactos causados pela deriva do herbicida 2,4-D em culturas sensíveis. No entanto, as informações existentes na literatura para dar suporte às possíveis liberações futuras de culturas resistentes a este herbicida são escassas. Os experimentos foram conduzidos em casa-de-vegetação e laboratório da Escola Superior de Agricultura \"Luiz de Queiroz\" - Universidade de São Paulo - ESALQ/USP. Os objetivos da presente pesquisa foram: (i) avaliar a influência do herbicida 2,4-D no desenvolvimento das culturas do algodão e soja em, diferentes estádios fenológicos, (ii) avaliar os possíveis danos causados pela deriva do herbicida 2,4-D no crescimento e desenvolvimento das culturas de algodão e soja, em diferentes estádios fenológicos, e (iii) observar através da microscopia eletrônica de varredura possíveis alterações nas estruturas foliares das plantas de algodão e soja após o contato com o herbicida. Curvas de doseresposta foram obtidas a partir de experimentos conduzidos em casa-de-vegetação. Para isso, foram conduzidos dois ensaios, sendo os tratamentos com o herbicida aplicado quando as plantas atingiram os estágios fenológicos: V2 (segundo nó vegetativo); R1 (início da floração para a cultura de soja), F1 (início da floração da cultura de algodão); e R6 (vagens da soja com enchimento pleno e folhas verdes) e C1 (algodão no final do florescimento efetivo e frutificação plena). No primeiro experimento os tratamentos utilizados foram: 0D (testemunha), 0,25D, 0,5D, 1D, 2D e 4D, sendo D a dose recomendada do 2,4-D, e no segundo experimento as doses utilizadas foram: 0D, 1D, 0,1D, 0,01D, 0,001D, 0,0001D. Utilizando as mesmas plantas da primeira etapa da pesquisa foram feitas amostragens das folhas para a caracterização foliar através de microscopia eletrônica de varredura. O 2,4-D comprometeu significativamente o crescimento e desenvolvimento das plantas de soja em todos os estádios fenológicos, com fitotoxicidade superiores a 65%. Resultados semelhantes foram obtidos na cultura do algodão, onde o menor nível de dano foi de 42,5% relativa à aplicação do herbicida no estádio fenológico R6 na dose de 0,25D. Observando os tratamentos nas subdoses do herbicida, na soja, verificou se que a maior porcentagem de fitotoxicidade foi obtida na dose de 0,1D, em todos os estádios fenológicos, os níveis de dano foram superiores a 50% na última avaliação. Em relação à cultura do algodão resultados semelhantes foram obtidos, com exceção do estádio fenológico R6, quando todos os estádios apresentaram porcentagem de fitotoxicidade superior a 40%. Em relação às características foliares do algodão e soja após aplicações de 2,4-D através da análise das características foliares em microscópio eletrônico de varredura, após a aplicação do herbicida, observou-se que o produto promoveu alterações nas estruturas foliares de algodão e soja em todas as doses estudadas.
The herbicide 2,4-D is used to control weeds in post-emergence conditions in crops which it is selective, as well in pre-planting vegetation management, however, due to its physical-chemical characteristics it may cause damage to susceptible neighbor crops, by the drift of the molecule during the spray. Therefore, it is of fundamental importance the technical knowledge of the impacts caused by the drift of the molecule during the application. The experiments were conducted in greenhouse and in the laboratory of the College of Agriculture \"Luiz de Queiroz\". So the objectives of this study were (i) to evaluate the possible damage caused by 2,4-D in the initial development of cotton and soybean crops (ii) to evaluate the possible damage caused by 2,4-D drift in the initial development of cotton and soybean crops and (iii) to observe by electron microscopy scanning possible changes in leaf structure of plants cotton and soybeans after contact with the herbicide. Dose-response curves were obtained from experiments conducted in the greenhouse. For that, it was conducted two trials, being the treatments with the herbicide sprayed when the plants reached the following phenological stages: V2 (second vegetative node); R1 (beginning of flowering for soybeans) and F1 (beginning of flowering in cotton); and R6 (soybean pods with full filling and green leaves) and C1 (cotton at the end of effective flowering and fruiting full). In the first experiment the doses were related to the effect of doses (0D, 0.25D, 0.5D, 1D, 2D, 4D), where D is the recommended dose of the herbicide 2,4-D, and in the second experiment evaluated the effect of underdoses (0D, 1D, 0.1D, 0.01D, 0.001D and 0.0001D). Using the same plants of the first and second step of the research it was sampled leaves for the foliar characterization by scanning electron microscopy. The 2,4-D affected significantly the growth and development of the soybean plants in all phenological stages, with phytotoxicity superior to 65%. Similar results were obtained in cotton, where the lower level of damage was 42.5% on the application of the herbicide on growth stage R6 with the 0.25D dose. Regarding to the application of doses of the herbicide 2,4-D on soybeans, it was observed that the highest percentage of phytotoxicity to the crop was at the dose of 0.1D; in all growth stages the damage levels were above 50% in the last evaluation. Regarding to the cotton crop, similar results were obtained, except for the R6 growth stage, every stage showed higher percentage of phytotoxicity than 40%. Regarding to the characteristics of the cotton and soybean leaves following 2,4-D application, it was found that the product caused alterations in leaf structure of the plants in all doses.

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40

Alexandre, Paula. "Développement des plaques du toit et du plancher dans le cerveau moyen : rôle de l' organisateur isthmique." Paris 6, 2005. http://www.theses.fr/2005PA066077.

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41

Elofsson, Johan, and Sven Arne Karlsson. "Kreditbedömning med kassaflödesanalys : En studie av Länsförsäkringar Älvsborg/L Finans AB." Thesis, Mälardalens högskola, Akademin för hållbar samhälls- och teknikutveckling, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-14867.

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Bakgrund Bankers kreditgivning till företag föregås av en noggrann granskning och kontroll av företagets status. För att sänka riskerna till en acceptabel nivå används olika bedömningsverktyg. Kreditbedömingen skiljer sig dock mellan olika banker. Vissa tar in mer information och gör en grundligare riskanalys, medan andra går mer på magkänsla. Kassaflödesanalysen är ett verktyg som vissa kreditgivare använder sig av. Analysen är ett komplement till resultat- och balansräkningen. Länsförsäkringar Älvsborgs (LF) är en relativt ny aktör på kreditmarknaden. De vill utöka sin kreditverksamhet och effektivisera kreditbedömningsprocessen. Syfte Syftet med rapporten är att undersöka hur kreditvärderingsarbetet hos LF kan förbättras och effektiviseras. Effektiviseringen avser primärt total handläggningstid för ett kreditärende och sekundärt personalens arbetstid för ett ärende. Undersökningen syftar också till att se hur kassaflödesanalys kan inkluderas i kreditbedömningsprocessen. Metod Undersökningen är en kvalitativ studie, som med hjälp av intervjuer och litteraturinsamling av olika dokument skapar en empirisk bas. Kvalitativa undersökningar försöker förklara sambandet mellan teori och bakomliggande sociala faktorer för en frågeställning. Slutsatser Kreditrisken vid utlåning minskar om kassaflödesanalys införs som standardiserad arbetsmetod vid handläggning av kreditärenden hos LF. De kan också effektivisera den totala handläggningstiden, när beslutsfattandet delegeras ut i organisationen. Färre kreditärenden behöver handläggas av högre instanser inom LF, vilket leder till minskad total arbetsinsats och högre effektivitet. Handläggarnas arbetstid för respektive kreditärende ökar. Viss tidseffektivisering uppnås dock när beslutsunderlaget blir tydligt och handläggaren inte behöver sitta och fundera på sitt beslut, eller lägga tid på att redogöra för beslutsunderlaget hos högre instans. Kassaflödesanalysen bör vara integrerad i det befintliga KB (kreditberedning) systemet för att handläggningen skall fungera effektivt. LF bör också genomföra en ordentlig utbildningsinsats i samband med systemändringen.

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42

Nord, Niklas, and Robin Sundqvist. "Brandskydd av bok (Fagus sylvatica L.) impregnerat med fenolharts och ammoniumdivätefosfat." Thesis, Linnéuniversitetet, Institutionen för skog och träteknik (SOT), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-104991.

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Trä är ett biologiskt material som anses vara både förnyelsebart och hållbart byggnadsmaterial vilket har gjort att det har blivit populärare att bygga i trä. En av de största utmaningarna med att använda trä som konstruktionsmaterial i större byggnader och höghus är brandsäkerheten. I det här examensarbetet har provbitar av bok (Fagus sylvatica L.) vakuumimpregnerats med fenolformaldehydharts (PF) och olika nivåer av ammoniumdivätefosfat (ADF). Provbitarna användes sedan för att testa träets dess mekaniska styrka, hygroskopiska förmåga samt brandegenskaper. Resultaten från studien visar att vakuumimpregnering med kemikalierna ammoniumdivätefosfat (ADF) och fenolformaldehydharts (PF) i trä ger ett virke som är starkare, mer formstabilt och som har ett bättre brandskydd jämfört med obehandlat trä.

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43

Franco, Fernando Alves de Lima. "Caracterização da região genômica META 1 de Leishmania (Leishmania) amazonensis e comparação com a região ortóloga de L. (L.) major." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-03122008-102437/.

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A caracterização de sequências codificadoras presentes nas vizinhanças do gene META 1 permitiu a identificação de alguns genes expressos preferencialmente em estágios infectivos de L. (L.) amazonensis. Um dos genes presentes é regulado de forma distinta, observando-se maior abundância do RNA em formas amastigotas. Este gene foi denominado LaLRR17 por codificar uma proteína contendo em sua região central 6 repetições ricas em leucina (LRR). As LRR são motivos presentes em diversas famílias de proteínas e são responsáveis pela formação de uma estrutura capaz de estabelecer interações protéicas. A região central da proteína LRR17 apresentou similaridade com a porção carboxi-terminal da proteína NOD 3 humana. A proteína LRR17 foi localizada no citosol de macrófagos infectados com L. (L.) amazonensis. Para caracterizar a função da proteína LRR17 foram obtidas linhagens de L. (L.) amazonensis expressoras do gene LmjLRR17. Essas linhagens mutantes foram mais infectivas em macrófagos in vitro quando comparadas com a linhagem selvagem. Avaliamos também o papel das proteínas NOD 1 e NOD 2 na infecção por L. (L.) amazonensis e L. (L.) major para estabelecer a possível relação da proteína LRR17 na interação com essas vias de defesa celular do macrófago.
The characterization of coding sequences in the vicinity of the META 1 gene allowed the identification of some genes preferentially expressed in L. (L.) amazonensis infective stages. One of the identified transcripts presents a distinct pattern of expression with higher levels of mRNA in amastigotes. This gene was named LaLRR17 since it encodes a 72 kDa protein with 6 leucine-rich repeats (LRR) in its central region. Leucine-rich repeats (LRR) are present in several families of proteins and are responsible for the formation of a structure capable of establishing protein interactions. The central region of the LRR17 protein showed similarity with the carboxyl-terminal portion of the NOD 3 human protein. The LaLRR17 protein is secreted to the cytoplasm of L. (L.) amazonensis-infected macrophages. To characterize the function of the LRR17 protein we obtained strains of L. (L.) amazonensis expressing the LmjLRR17 gene. These mutant strains were more infective to macrophages in vitro when compared with the wild type strain. We also evaluated the role of NOD 1 and NOD 2 proteins in infections with L. (L.) amazonensis and L. (L.) major to investigate a possible role of the LRR17 protein in the interaction with these defense pathways in macrophages.

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44

Benini, Gabriella. "Studio di celle solari innovative basate su "multiple electron-hole generation"." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8936/.

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L’aumento dei consumi energetici e la sempre maggiore attenzione posta al tema ambientale fanno delle energie alternative una valida alternativa alle fonti , quali carbone e petrolio,che presentano una elevata generazione di gas serra . Tra le varie fonti alternative di energia un ruolo preponderante è stato assunto dal solare fotovoltaico, che dagli anni ’80 ad oggi ha conosciuto un rapido sviluppo sia in termini di ricerca che di utilizzo su larga scala. Negli ultimi anni tutti gli studi si stanno concentrando su un nuovo tipo di fotovoltaico, quello di terza generazione , il cui scopo è quello di ottenere dispositivi che possano garantire elevate efficienze in modo tale che la tecnologia fotovoltaica sia in grado di affermarsi definitivamente nel settore dell’energia. Il presente lavoro di tesi analizza il processo di conversione fotovoltaica ed il principio di funzionamento delle celle solari . I limiti termodinamici per l'efficienza di conversione di celle solari a singola giunzione sono stati discussi nella tesi. E' presentata nella tesi una rassegna delle principali strategie per il superamento dei limiti termodinamici per l'efficienza di una cella solare a singola giunzione . Sono stati analizzati : •il processo di rilassamento intrabanda dei nanocristalli ; •la generazione multipla di eccitoni (MEG) •il processo di Generazione di eccitoni multipli in nanocristalli di silicio colloidali (MEG in Si NCs). Tali risultati rivestono un particolare interesse per lo sviluppo di celle solari innovative , ad alta efficienza di conversione , utilizzando un materiale facilmente reperibile ed economico come appunto è il Silicio.

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McAlister, Judith Emma. "A realistic evaluation of transition programmes in two secondary schools in a small multi-cultural city in the Midlands : how are the needs of vulnerable young people met during the transition from primary to secondary school?" Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3921/.

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Background: The transition from primary to secondary school marks a potentially problematic experience for young people who have special educational needs, for those who are socially marginalised or thought to be vulnerable for a range of alternative reasons (Jindal-Snape and Miller, 2008). The research literature has primarily concentrated on the effects of transition on young people, without exploring what works for whom and in what ways. Purpose of the Research: The aim of the research thesis is to explore how two individual transition programmes meet the needs of vulnerable young people prior to, during and after the transfer to secondary school. The research will ask: “What are the contextual factors and the mechanisms by which transition programmes lead to successful transition outcomes for vulnerable young people?” Methodology: The research will utilise a mixed methods design comprising a comparative Realistic Evaluation methodology (Pawson and Tilley, 1997). Data related to students’ and staff views of the transition process was obtained through focus group and semi-structured interview methods, and outcome data, measuring the degree of successful transition for participants, was conducted using two standardised questionnaires: the School Children’s Happiness Inventory (Ivens, 2007) and the Psychological Sense of School Membership Scale (Goodenow, 1993). The psychological mechanisms which were triggered by the transition programmes were extracted using a Realistic Evaluation approach, and a series of seven Programme Theories was developed. The thesis concludes with a consideration of the limitations of the study before outlining implications for transition practice in schools and for Educational Psychology practice.

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46

Santos, Maurício Fernandes dos. "TERMINAÇÃO DE CORDEIROS AO PÉ DA MÃE EM PASTAGEM CULTIVADA DE AZEVÉM (Lolium multiflorum L.) + TREVO VERMELHO (Trifolium pratense L.) COM E SEM O EMPREGO DA ALIMENTAÇÃO PRIVATIVA AO CORDEIRO." Universidade Federal de Santa Maria, 2007. http://repositorio.ufsm.br/handle/1/10689.

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The experiment objectified the termination of lambs to the foot of the mother in pasture cultivated of ryegrass and red clover with and without creep-feeding to the lamb. Evaluations in the performance, characteristics of carcass, production of commercial cuts and production of the components had been carried through not-carcass in the lambs kept to the foot of the mother and submitted to the alimentary treatments: PAST = pasture cultivated of ryegrass and red clover; APT = pasture cultivated of ryegrass and red clover + creep-feeding to the lamb during all the period of use of the grass; AP42 = pasture cultivated of ryegrass and red clover + creep-feeding to the lamb from 42 days after beginning of the use of the grass. For all the evaluated parameters of the grass, did not have interaction (P>0.05) between treatment and period, did not have difference between treatments (P>0.05) for the parameters evaluated in the grass. Animals that had received creep-feeding had presented greater (P<0.05) profit of daily average weight and lesser (P<0.05) number of days to reach the weight established of slaughter in relation to that they had only remained in pasture. The components carcass had not differed (P>0.05) in the alimentary treatments. The weight of slaughter of 28 kg was only reached in 43, 71 and 86% of the animals of treatments PAST, AP42 and APT, respectively. The job of creep-feeding better does not provide to quality and nor carcass yield, for the lambs slaughtered with 28kg. In handling pastures of similar form, the creep-feeding promotes additive effect on the efficiency of termination of the animals.
O experimento objetivou a terminação de cordeiros ao pé da mãe em pastagem cultivada de azevém e trevo vermelho com e sem a alimentação privativa ao cordeiro. Foram realizadas avaliações no desempenho, características de carcaça, produção de cortes comerciais e produção dos componentes não-carcaça nos cordeiros mantidos ao pé da mãe e submetidos aos tratamentos alimentares: PAST = pastagem consorciada de azevém e trevo vermelho.; APT = pastagem consorciada de azevém e trevo vermelho + alimentação privativa ao cordeiro durante todo o ciclo de uso do pasto; AP42 = pastagem consorciada de azevém e trevo vermelho + alimentação privativa ao cordeiro a partir de 42 dias após inicio da utilização do pasto. Para todos os parâmetros avaliados do pasto, não houve interação (P>0,05) entre tratamento e período, não houve diferença entre tratamentos (P>0,05) para os parâmetros avaliados no pasto. Animais que receberam alimentação privativa apresentaram maior (P<0,05) ganho de peso médio diário e menor (P<0,05) número de dias para atingir o peso estabelecido de abate em relação a aqueles que somente permaneceram em pastagem. Os componentes não carcaça não diferiram (P>0,05) nos tratamentos alimentares. O peso de abate de 28 kg foi atingido somente em 43, 71 e 86 % dos animais dos tratamentos PAST, AP42 e APT, respectivamente. O emprego da alimentação privativa não proporciona melhor qualidade e nem rendimento na carcaça, para cordeiros abatidos aos 28kg. Em pastagens manejadas de forma similar, a alimentação privativa promove efeito aditivo sobre a eficiência de terminação dos animais.

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Panafieu, Jean-Baptiste de. "L'Alimentation hivernale du Merlan, Merlangius merlangus L. 1758, en Mer du Nord." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb37597128d.

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Fidele, Mickaël Poeaheiau. "L' évolution statutaire des collectivités d'outre-mer : l'exemple de la Polynésie française." Aix-Marseille 3, 2009. http://www.theses.fr/2009AIX32027.

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Les collectivités d'outre-mer (COM) sont les seules collectivités locales capables de voir leur statut évoluer selon leurs intérêts propres. Lorsque leur évolution statutaire est une finalité, elle peut les conduire dans deux directions opposées : l'assimilation, auquel cas, elles se transformeront en département d'outre-mer (DOM), ou l'indépendance, qui les conduira au statut d'Etat. Lorsque l'évolution statutaire des COM est un moyen, elle se concrétise par une autonomie qui, elle-même, vise deux objectifs : d'une part, accéder à l'égalité des droits avec la métropole, et d'autre part, atteindre le développement. L'autonomie polynésienne est intéressante dans la mesure où elle brouille les logiques de l'évolution statutaire. En effet, parce que les deux objectifs précités sont loin d’être atteints en Polynésie, l'autonomie est en quelque sorte devenue une finalité. S'ensuit une surenchère statutaire qui a débuté en 1957 et qui s'est interrompue en 2004. Néanmoins, l'autonomie ne correspondant pas à un projet de société, il était inévitable qu'une finalité plus authentique s'y substitue, à savoir l'indépendance. Le projet de thèse se propose d'aborder successivement les trois logiques de l'évolution statutaire suivies par la Polynésie française : l'égalité des droits (décentralisation des fonctions de l’Etat providence), le développement économique, social et culturel (transfert de compétences matérielles) et l'indépendance (formation d’un embryon de citoyenneté infranationale, renforcement du pouvoir normatif local)
The overseas countries (COM) are the only local authorities able to see their status evolve according to their specificities. When their statutory evolution is an objective, it can lead them into two opposite directions: the assimilation, in which case, they will be transformed into French overseas department (DOM), or the independence, which will lead them to the status of State. When the statutory evolution of the COM is a means, it leads to autonomy which, itself, aims at two objectives : on one hand, reach the equality of the rights with the metropolis, and on the other hand, reach the development. The autonomy of the French Polynesia is interesting because it blurs the logics of the statutory evolution. Indeed, the two objectives quoted previously, are far from being reached in the archipelago, the autonomy became in a sense an aim. A statutory overbid follows which began in 1957 and finished in 2004. Nevertheless, the autonomy not corresponding to a project of society, it was inevitable that a more authentic end substitutes itself for it, namely the independence. The project of thesis suggests approaching successively three logics of the statutory evolution followed by the French Polynesia : the equality of the rights (the decentralization of the welfare state’s functions), the economic, social and cultural development (the transfer of the material competences) and the independence (the acknowledgement of a local citizenship, the reinforcement of the local standard power)

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Schepker, Kristy Lee. "Complex Thermal Histories of L Melt Breccias NWA 5964 and NWA 6580." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/1835.

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To constrain the thermal histories of two complex L chondrite melt breccia samples (NWA 5964 and NWA 6580) we compare textures and chemical compositions of metal and sulfide to L melt rock (NWA 6454 and NWA 6579) and strongly shocked (shock stage S6) (NWA 4860) samples. The inferred thermal histories can be used to evaluate formation settings on the L chondrite parent body. The L melt samples probably formed as different melt units within warm but largely unmelted material relatively close to the surface of the parent body, and the same is true for the S6 sample, except it experienced less melting. The breccia samples likely formed deeper, below different impact craters, by the injection of shock melt into a cooler chondritic basement. Carbide grains in the melt breccias could have formed by a contact metamorphic process caused by heating of the chondritic basement in proximity to the melt. Within the melt regions of the various samples, inferred cooling rates are on the order of 1-10 °C/sec, whereas in the chondritic portions of the melt breccias, the inferred cooling rates are many orders of magnitude slower, ~1-100 °C/My. The complex intergrowths of metal and FeS (hereafter referred to as dendritic grains) within the melt are recording cooling rates above the metal-sulfide eutectic, while the metal grains outside of the melt regions are recording cooling rates at much lower temperatures. It is likely the melt regions in the breccias cooled substantially prior to coming to rest against the chondritic basement, and thereafter the melt-chondrite rocks cooled more slowly.

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Franchini, Mattia. "Analisi delle tecniche di elettrofilatura e possibili implementazioni metodologiche." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/14786/.

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L’interesse nel campo della produzione delle nanofibre, tramite la tecnica elettrofilatura, è sempre maggiore. Allo scopo di capire le potenzialità e lo stato dell’arte della tecnica, si è effettuata un’analisi su alcuni studi pubblicati, per verificare il livello raggiunto, i limiti e, come applicare con maggiore efficacia la medesima, che ad oggi assume un ruolo sempre più di rilievo nella fabbricazione delle nanofibre. Il motivo, per il quale la tecnica si è sviluppata, va ricercato nella sua vasta gamma di polimeri sintetici e biopolimeri, utilizzabili per la produzione di nanofibre, sempre più variegate . In questo elaborato si cerca di capire come ridurne i costi, per una produzione a livello industriale e come, ottenere delle fibre sempre più adatte all’applicazione sul corpo umano. Si indaga anche sulla possibilità di usare gli scaffold come mezzi su cui far prolificare colonie di cellule trapiantabili.

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Dissertations / Theses on the topic 'L-Met'

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