Relevant bibliographies by topics / L-PRF membranes

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'L-PRF membranes'

Author: Grafiati
Published: 4 September 2021
Last updated: 29 July 2025

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Journal articles on the topic "L-PRF membranes"

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Lara, Cesar, Alejandro Bezmalinovic, Claudio García-Herrera, Susana Ríos, Loreto M. Valenzuela, and Constanza E. Martínez. "Leukocyte- and Platelet-Rich Fibrin (L-PRF) Obtained from Smokers and Nonsmokers Shows a Similar Uniaxial Tensile Response In Vitro." Biomedicines 11, no. 12 (2023): 3286. http://dx.doi.org/10.3390/biomedicines11123286.

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We evaluated and compared the biomechanical properties of Leukocyte-and Platelet Rich Fibrin L-PRF clots and membranes derived from smoker and nonsmoker donors. Twenty venous-blood donors (aged 18 to 50 years) were included after signing informed consent forms. L-PRF clots were analyzed and then compressed to obtain L-PRF membranes. L-PRF clot and membrane samples were tested in quasi-static uniaxial tension and the stress–stretch response was registered and characterized. Furthermore, scanning electron microscope representative images were taken to see the fibrin structure from both groups. T
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Khorshidi, Hooman, Saeed Raoofi, Rafat Bagheri, and Hodasadat Banihashemi. "Comparison of the Mechanical Properties of Early Leukocyte- and Platelet-Rich Fibrin versus PRGF/Endoret Membranes." International Journal of Dentistry 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/1849207.

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Objectives. The mechanical properties of membranes are important factors in the success of treatment and clinical handling. The goal of this study was to compare the mechanical properties of early leukocyte- and platelet-rich fibrin (L-PRF) versus PRGF/Endoret membrane.Materials and Methods.In this experimental study, membranes were obtained from 10 healthy male volunteers. After obtaining 20 cc venous blood from each volunteer, 10 cc was used to prepare early L-PRF (group 1) and the rest was used to get a membrane by PRGF-Endoret system (group 2). Tensile loads were applied to specimens using
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Palmeira Esteves Schleinstein, Camilla, André Carlos de Freitas, Viviane Palmeira da Silva, Naiadja De Santana Cerqueira, Maria Cristina Teixeira Cangussu, and Luciana Maria Pedreira Ramalho. "CHARACTERIZATION OF PHYSICAL AND CELLULAR PROPERTIES OF MEMBRANES OF L-PRF PRODUCED BY DIFFERENT CENTRIFUGES/ CENTRIFUGATION PROTOCOLS." Brazilian Journal of Implantology and Health Sciences 6, no. 1 (2024): 1773–90. http://dx.doi.org/10.36557/2674-8169.2024v6n1p1773-1790.

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Leukocyte and platelet-rich fibrin (L-PRF), an essential source of cytokines and growth factors, has been widely used to regulate the healing process. The quality of the L-PRF obtained is dependent on technical factors and the centrifugation protocol used. Thus, the present study aimed to macro and microscopically evaluate the formation of the L-PRF membrane/clot in two centrifuge models and protocols recommended by manufacturers. Four blood samples from 8 healthy volunteers undergoing rehabilitation surgery with dental implants were used. In group 1 of the Montserrat centrifuge (model 80-2B 1
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Serafini, Giorgio, Marco Lollobrigida, Lorenzo Fortunato, et al. "Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation." Case Reports in Dentistry 2020 (June 12, 2020): 1–6. http://dx.doi.org/10.1155/2020/5073519.

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Leukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. This report describes a case of alveolar ridge preservation with L-PRF membranes. Postextractive alveolar healing was then assessed through a histologic and histomorphometric analysis. A patient requiring tooth extraction and subsequent implant rehabilitation was treated with simple extraction and socket filling with L-PRF membranes. Implant placement was performed at 3 months, and a bon
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Simões-Pedro, Mara, Pedro Maria B. P. S. Tróia, Nuno Bernardo Malta dos Santos, António M. G. Completo, Rogerio Moraes Castilho, and Gustavo Vicentis de Oliveira Fernandes. "Tensile Strength Essay Comparing Three Different Platelet-Rich Fibrin Membranes (L-PRF, A-PRF, and A-PRF+): A Mechanical and Structural In Vitro Evaluation." Polymers 14, no. 7 (2022): 1392. http://dx.doi.org/10.3390/polym14071392.

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Predictable outcomes intended by the application of PRF (platelet-rich fibrin) derivative membranes have created a lack of consideration for their consistency and functional integrity. This study aimed to compare the mechanical properties through tensile strength and analyze the structural organization among the membranes produced by L-PRF (leukocyte platelet-rich fibrin), A-PRF (advanced platelet-rich fibrin), and A-PRF+ (advanced platelet-rich fibrin plus) (original protocols) that varied in centrifugation speed and time. L-PRF (n = 12), A-PRF (n = 19), and A-PRF+ (n = 13) membranes were sub
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Aragosa, Federica, Gerardo Fatone, Chiara Caterino, et al. "Evaluation of the Effects of Autologous Leukocyte- and Platelet-Rich Fibrin Membranes for Treating Chronic Wounds: A Prospective Study." Animals 15, no. 1 (2025): 112. https://doi.org/10.3390/ani15010112.

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(1) Background: The aim of this prospective study was to evaluate the efficacy of topical application of leukocyte- and platelet-rich fibrin (L-PRF) membranes for treating chronic cutaneous wounds in dogs. (2) Methods: Chronic wounds unresponsive to conventional treatments were assessed on digital photographs and classified using the Bates-Jensen Wound Assessment Tool (BWAT). Each lesion was treated with L-PRF membranes. Epithelialization, granulation tissue formation, wound healing rate, and contraction were statistically analyzed during follow-up. (3) Results: All but one of the cases were t
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Francisco, Inês, Francisco Vale, Victor Martin, Maria Helena Fernandes, and Pedro Sousa Gomes. "From Blood to Bone—The Osteogenic Activity of L-PRF Membranes on the Ex Vivo Embryonic Chick Femur Development Model." Materials 14, no. 24 (2021): 7830. http://dx.doi.org/10.3390/ma14247830.

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(1) Background: To evaluate the effects of the direct and indirect contact of leukocyte and platelet-rich fibrin (L-PRF) on bone development, in an ex vivo embryonic chick femur model. (2) Methods: Both sections of L-PRF membranes (red and yellow portions) were evaluated with scanning electron microscopy and histochemical staining. The in vivo angiogenic activity was evaluated using a chorioallantoic membrane model. The osteogenic activity was assessed with an organotypic culture of embryonic chick femora through direct and indirect contact, and assessment was conducted by microtomographic and
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Perussolo, José Maurício, Mhárllon Rutyna Santos, Jeferson Luis de Oliveira Stroparo, et al. "Use of platelet- and leukocyte-rich fibrin (l-prf) in bisphosphonate-related osteonecrosis of the jaw (bronj) in rats - split-mouth study." Conjecturas 22, no. 8 (2022): 74–87. http://dx.doi.org/10.53660/conj-1125-s11.

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This study aimed to clinically evaluate the effect of platelet- and leukocyte-rich fibrin (L-PRF) membranes in preventing bisphosphonate-related osteonecrosis of the jaw (BRONJ) in rats. In this study, twelve Wistar rats (six males and six females) were used. A split-mouth study was performed; the right-side was used as treatment, with treatment of platelet- and leukocyte-rich fibrin membranes (L-PRF group, LPRFG), and the left-side received no intervention as control (control group, CG). The rats received intravenous Zolendronate (Zol) (80 ug/kg/week) injections during nine weeks to induce th
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Sousa, Leandro Lécio de Lima, Daiane Fermino Brunale, Gustavo Vicentis Oliveira Fernandes, Gabriela Giro, and Marcelo de Faveri. "A Comparison of the Dimensional Characteristics and Plasma Parameters of Different Centrifuges Used for the Preparation of Autologous Platelet Concentrates: A Randomized Correlational Study." Materials 18, no. 2 (2025): 414. https://doi.org/10.3390/ma18020414.

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Objective: The objective of this study was to evaluate autologous platelet-rich fibrin (PRF) membrane weights and measurements after production by different centrifuges. Moreover, the values obtained with blood cellular components were correlated. Methods: Twelve systemically healthy participants underwent dental implant surgery associated with PRF membranes as the graft biomaterial at the implant site. Prior to the surgical procedure, the chosen participants underwent blood count and coagulogram tests and presented on the surgical day. Nine tubes containing 10 mL of venous blood were collecte
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MOHAMMED, Jiyar. "Efficacy of Platelet Rich Fibrin on Angiogenesis." Journal of Duhok University 23, no. 1 (2020): 172–77. http://dx.doi.org/10.26682/csjuod.2020.23.1.18.

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In this experiment we used platelet-rich fibrin (L-PRF) with the protocol of its production, in this study we tried to investigate the angiogenetic efficacy of L-PRF on s soft tissue. Blood samples of 8 sheep were used to establish the protocol of the L-PRF formation to develop the work. The mucoperiosteal flaps were filled with autologous L-PRF in the mandible and maxillary jaws of the sheep. Samples taken from the surgical sites stained with haematoxylin and eosin for diagnosis of the sections, then immunohistological tests were confirmed on these sections. We noticed that after 14 days of m
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Dissertations / Theses on the topic "L-PRF membranes"

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Simões, Rodrigo de Oliveira. "Qualidade de café (Coffea arabica L.) pré-processado por via seca." Universidade Federal de Viçosa, 2009. http://locus.ufv.br/handle/123456789/3542.

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Made available in DSpace on 2015-03-26T13:23:24Z (GMT). No. of bitstreams: 1 texto completo.pdf: 2293485 bytes, checksum: a74ed7d0d350ed68a2888bbcca886ec0 (MD5) Previous issue date: 2009-02-16<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The maturity stage physiological of coffee fruit after their harvest may influence on the physiological quality of grains and the final quality of coffee drink, mainly because of their peculiarities. The objective of this study was to verify some aspects of pre-process of coffee in coconut, harvesting at different percentages of cherry
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Liu, Guodong. "Regulation of alternative pre-mRNA splicing by depolarization/CaMKIV." the American Society for Biochemistry and Molecular Biology, 2009. http://hdl.handle.net/1993/14168.

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Alternative pre-mRNA splicing is often controlled by cell signals (1-3). Membrane depolarization/calcium (Ca2+) signaling controls alternative splicing of a group of genes in neurons and endocrine cells (4-9), with important implications in memory formation or secretion of hormones and neurotransmitters (10-15). However, the underlying molecular basis remains largely unknown. In rat GH3 pituitary cells, BK potassium channels control cellular electrical firing, which is critical for the release of growth hormone and prolactin. Inclusion of the STREX exon of the Slo1 gene encoding the channel α
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Lopes, Michel Fernandes. "Reconstrução Maxilar com Aloenxertos Ósseos em bloco e membranas de L-PRF." Master's thesis, 2018. http://hdl.handle.net/10316/82701.

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Trabalho Final do Mestrado Integrado em Medicina Dentária apresentado à Faculdade de Medicina<br>Introduction: Implant-supported rehabilitation requires the existence of sufficient bone volume. The phenomenon of edentulous areas’ resorption may compromise the insertion of endosseous dental implants and disadvantage the biomechanics of prosthetic rehabilitation. In cases of decreased bone volume, reconstruction of maxillary bone defects is a crucial success factor in the patient's oral rehabilitation. Aim: This study aims to verify the applicability and efficacy of bone allografts in the recons
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Mateus, Dina do Carmo Batista. "Avaliação clínica da influência da aplicação da membrana de L-PRF na cicatrização após exodontia de terceiros molares inclusos e semi inclusos." Master's thesis, 2020. http://hdl.handle.net/10400.26/35039.

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Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz<br>O uso de agregados plaquetários tem crescido muito em diversas áreas da medicina, não sendo diferente na medicina dentária, onde o seu uso passou a ser muito frequentemente falado, aquando da sua utilização em cirurgias de elevação do seio maxilar. O L-PRF tem uma maior facilidade de obtenção em relação ao PRP, o que tem tornado o seu uso mais difundido. A grande vantagem em se utilizar concentrados de plaquetas está na presença de mediadores inflamatórios e células de defesas em grande concentração no leito c
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Knedlík, Tomáš. "Glutamátkarboxypeptidasa II jako cíl farmaceutického zásahu a molekulární adresa pro léčbu nádorových onemocnění." Doctoral thesis, 2018. http://www.nusl.cz/ntk/nusl-372828.

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Glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA), is a membrane metallopeptidase overexpressed on most prostate cancer cells. Additionally, GCPII also attracted neurologists' attention because it cleaves neurotransmitter N-acetyl-L-aspartyl-L-glutamate (NAAG). Since NAAG exhibits neuroprotective effects, GCPII may participate in a number of brain disorders, which were shown to be ameliorated by GCPII selective inhibitors. Therefore, GCPII has become a promising target for imaging and prostate cancer targeted therapy as well as therapy of neuronal d
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Books on the topic "L-PRF membranes"

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Endlich, Karlhans, and Rodger Loutzenhiser. Regulation of vasomotor tone in the afferent and efferent arterioles. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0208.

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Pre-glomerular vessels are regulated by membrane potential alterations affecting the activity of L-type voltage-activated Ca2+ channels; whereas voltage-independent mechanisms regulate the efferent arteriole, notably influenced by angiotensin II and therefore by angiotensin converting enzyme inhibitors, and by non-steroidal anti-inflammatory drugs.These properties underlie the physiologic control of glomerular capillary pressure, for example, by prostaglandin E2, during conditions of reduced renal perfusion and the stabilization of glomerular capillary pressure when the kidney is exposed to pr
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Book chapters on the topic "L-PRF membranes"

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Hermida-Nogueira, Lidia, Juan Blanco, and Ángel García. "Secretome Profile of Leukocyte-Platelet-Rich Fibrin (L-PRF) Membranes." In Methods in Molecular Biology. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2978-9_14.

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El-Ghazaly, G. A., and S. Nilsson. "Development of tapetum and orbicules of Catharanthus roseus (Apocynaceae)." In Pollen and Spores. Oxford University PressOxford, 1991. http://dx.doi.org/10.1093/oso/9780198577461.003.0017.

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Abstract The development of the tapetum and orbicules in Catharanthus roseus (L.) G. Don has been examined using transmission electron microscopy (TEM). Precursors of orbicules are formed as spheroidal vesicles within the tapetal cytoplasm and are associated with the endoplasmic reticulum. The pro-orbicules are extruded through the cell membrane of the tapetal cell and this coincides with the dissolution of the ta petal cell wall and the callosic wall of the microspores. The orbicules are developed by irregular deposition of sporopollenin on the pro-orbicules. A thin membranous layer is develo
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Belyaeva, Elena A. "Mechanism(s) of Membrane Permeability Transition in Liver Mitochondria of Lamprey, Lampetra fluviatilis L. during Pre-spawning Starvation." In Recent Developments in Medicine and Medical Research Vol. 16. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/rdmmr/v16/15318d.

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Dias, Janaína Nascimento, Mileyde Gordiano da Silva, Talita Pimentel Bessa, Cheila Maria Lins Bentes, and Marcos do Nascimento Bentes. "Capítulo 6 – HIV-AIDS, como tratar, o que fazer e o que não fazer durante o tratamento?" In Adole Saúde. Pontifícia Universidade Católica de São Paulo, 2025. https://doi.org/10.29327/5595655.1-6.

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A infecção pelo vírus do HIV pode ocorrer de diversas maneiras, tendo sua principal forma a via sexual por meio do sexo desprotegido. O vírus do HIV fica em um período de incubação por até 90 dias (que é o intervalo entre a data do primeiro contato com o patógeno até o início dos sinais e sintomas), calma aí, sei que você deve estar se perguntando o que é tudo isso, então vamos lá. O que é o HIV? O HIV (Vírus da Imunodeficiência Humana) é um vírus que ataca o sistema imunológico, que é como um “escudo” ou como também conhecidos “os soldadinhos” do sistema imunológico, são esses soldadinhos, os
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Conference papers on the topic "L-PRF membranes"

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Souza, Edgar Faccin de, Júlia Jessika de Freitas Luiz, Eduardo Moreschi, Monike Mayra da Silva Destefani, Polyane Mazucatto Queiroz, and Ana Regina Casaroto Moreschi. "Avaliação do infiltrado inflamatório de membranas de fibrina rica em plaquetas." In Avaliação do infiltrado inflamatório de membranas de fibrina rica em plaquetas. Editora Uningá, 2023. http://dx.doi.org/10.46311/ed.un.20221018125.

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O trabalho avaliou o número de leucócitos de membranas de fibrina rica em plaquetas e leucócitos (L-PRF) em diferentes tempos de armazenamento. As membranas foram obtidas de amostras de sangue de doadores voluntários e divididas em grupos (n=10): 0, 30 e 180 minutos. A contagem de leucócitos ocorreu com cortes microscópicos nos campos proximais ao coágulo, transição coágulo/fibrina e distais ao coágulo. Independente da área, não foi observada diferença significativa (p=0,9887) quanto ao número de leucócitos entre os tempos de armazenamento. A membrana de L-PRF apresentou constante contagem cel
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Emdadi, Arash, Mansour Zenouzi, and Gregory J. Kowalski. "Determining the Potential of Salinity Gradient Energy Source Using an Exergy Analysis." In ASME 2016 10th International Conference on Energy Sustainability collocated with the ASME 2016 Power Conference and the ASME 2016 14th International Conference on Fuel Cell Science, Engineering and Technology. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/es2016-59532.

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Mixing of fresh (river) water and salty water (seawater or saline brine) in a control fashion would produces an electrical energy known as salinity gradient energy (SGE). Two main conversion technologies of SGE are membrane-based processes; pressure retarded osmosis (PRO) and reverse electrodialysis (RED). In PRO, semipermeable membranes placed between the two streams of solutions allow the transport of water from low-pressure diluted solution to high-pressure concentrated solution. RED requires two alternating semipermeable membranes that allow the diffusion of the ions but not the flow of H2
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Gosselin, S. R., F. A. Simonen, and R. G. Carter. "Flaw Tolerance for Multiple Fatigue Cracks." In ASME 2005 Pressure Vessels and Piping Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/pvp2005-71141.

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Appendix L of Section XI provides for serviceability assessments of piping components that are subject to fatigue stresses. This appendix introduced a damage tolerance examination strategy to assure that components perform reliably throughout operating periods between inspections. Operating periods are based on fatigue crack growth analyses of postulated pre-existing cracks. Evidence from service experience shows that fatigue cracking occurrences at operating nuclear power plants often result from mechanisms that cause cracks to initiate and then grow at multiple locations on the inside surfac
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Rehse, K., U. Lukens, S. Leibring, V. Schein, and A. Kesselhut. "ANTITHROMBOTIC OLIGOAMINES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643439.

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We have found that oligoamines of the general formula R2−3X(R=-(CH2)m-NH-(CH2)n-Y) in which X and Y may be aliphatic, alicyc-lic, aromatic or even heterocyclic moieties are a new class of compounds which exhibit platelet aggregation inhibiting and anticoagulant activities in vitro and have antithrombotic properties in vivo. The compound RE 1492 (N,N’,N1’-Tris-4-phenylbutylbenzene-1,3,5-trimethanamine) is chosen as example to demonstrate these effects. In PRP the following IC50 of RE 1492 (inductor in brackets) were measured: 3 ¼mol/L (Collagen), 1 ¼mol/L (ADP, 2ndphase), 7.5 μmol/L (ADP, lstph
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Holmsen, Holm, Ole-Bjørn Tysnes, Adrie J. M. Verhoeven, Vidar M. Steen, Lindsey J. Moore, and Sissel Rongved. "INHIBITION BY NEOMYCIN OF AGONIST-INDUCED POLYPHOSPHOINOSITIDE METABOLISM AND RESPONSES IN HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644521.

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Signal processing in platelets seems to involve polyphosphoinositide (PPI) metabolism, although direct coupling between PPI metabolism and responses has not been proved. Neomycin binds tightly to PPIs and has been used to probe the involvement of PPI metabolism and responses in platelets. Neomycin(SO4)3 powerfully inhibited ADP- and adrenaline-induced aggregation of platelets in PRP. This was partly due to the sulphate anion; the chloride form was therefore prepared. Platelets were prelabelled in PRP with 32P-Pi. and transferred by gel filtration to a calcium-free Tyrode’s solution (GFP). Incr
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Vasiļjeva, Svetlana, Roberts Krumiņš, Gaļina Smirnova, et al. "Optimization of the production of sodium alginate derivatives." In 82nd International Scientific Conference of the University of Latvia. University of Latvia Press, 2024. https://doi.org/10.22364/iarb.2024.06.

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A natural polysaccharide sodium alginate, a salt of alginic acid, is widely used as a wetting and thickening agent in food, pharmaceuticals, cosmetics and other fields. Interest in the practical use of the derivatives of sodium alginate poses the problem of their convenient and cost-effective production. Two methods applied for the synthesis of uronic acids from sodium alginate were studied. The previously created method of Prof. A. Mirshafiey (Mirshafiey &amp; Lalander, 2024) has been tested in the laboratory. The method is based on the hydrolysis of sodium alginate with sulfuric acid followe
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Falcão, Iasmin Lima Da Costa, Kamila Almeida Freitas, Fernando Etros Martins Lessa, Márcio Roberto Pinho Pereira, and Silvia Fernandes Ribeiro Da Silva. "UTILIZAÇÃO DO TOCILIZUMAB NO TRATAMENTO DA COVID-19." In I Congresso Brasileiro de Imunologia On-line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/1005.

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INTRODUÇÃO: O Tocilizumab é utilizado para o tratamento de artrite reumatóide, artrite inflamatória juvenil e arterite de células gigantes. É um anticorpo monoclonal anti-receptor de interleucina-6 (IL-6), que age inibindo a ligação da citocina IL-6 aos seus receptores de membrana e solúveis, bloqueando a sua sinalização e reduzindo a reação inflamatória. Nas infecções graves por SARS-CoV-2 observa-se um estado hiper inflamatório com produção exacerbada de proteínas de fase aguda (proteína C reativa-PCR) e de citocinas pró-inflamatórias, como TNF-α, IL-1β, IL-6, IL-12 e IFN-γ, chamada de tempe
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Schleuning, W. D. "THE BIOCHEMISTRY AND CELL BIOLOGY OF SINGLE CHAIN UROKINASE TYPE PLASMINOGEN ACTIVATOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642956.

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Urokinase was discovered in the late nineteenth century, as an enzymatic principle in urine, that initiates the dissolution of blood clots. The basis of this phenomenon was recognized more than fifty years ago as the activation of plasminogen, the precursor of a tryptic protease, then known as profibrinolysin. Despite this long history, detailed data on the biochemistry of plasminogen activation have only become available recently. Urokinase (now designated urokinase-type plasminogen activator : u-PA) is synthesized and secreted as a single chain polypeptide (Mr-: 53,000) by many cell types. S
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Krishnamurthi, S., and V. V. Kakkar. "EXOGENOUSLY ADDED DIACYLGLYCEROL (DAG) AND ELEVATED INTRACELLULAR Ca2+ LEVELS CANNOT SUBSTITUTE FOR PROSTAGLANDIN END0PER0XIDES/ THROMBOXANE ki IN MEDIATING WEAK AGONIST-INDUCED PLATELET SECRETION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644507.

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We have compared the abilities of exogenously added U46619, the PG endoperoxide analogue and, sn-l-oleoyl 2-acetylglycerol (OAG) and sn-1,2-dioctanoylglycerol (diCg), the membrane-permeant DAG analogues, at restoring weak agonist-induced secretion in indomethacin (10μM)-treated platelets (I-PL) in the absence of endogenous PG/Tx synthesis. [14C]-5HT secretion from pre-loaded, washed human platelets was correlated with the levels of [Ca2+]i, using platelets loaded with quin 2. Concentrations of OAG (62-125μM) and diCg (15-30μM), which have previously been shown to be fully effective at activati
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