Academic literature on the topic 'L-Tyrosine-L-Arginine'

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Journal articles on the topic "L-Tyrosine-L-Arginine"

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Parfenova, Helena, Alex Fedinec, and Charles W. Leffler. "Role of tyrosine phosphorylation in the regulation of cerebral vascular tone in newborn pig in vivo." American Journal of Physiology-Heart and Circulatory Physiology 276, no. 1 (1999): H185—H193. http://dx.doi.org/10.1152/ajpheart.1999.276.1.h185.

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The role of tyrosine phosphorylation was investigated using protein tyrosine phosphatase inhibitors in newborn pigs equipped with a cranial window in vivo. We tested the hypothesis that cyclooxygenase and nitric oxide (NO) synthase are physiological targets for tyrosine phosphorylation in cerebral circulation. Phenylarsine oxide dilated pial arterioles and increased prostacyclin and prostaglandin E2 in cortical periarachnoid fluid; these responses were inhibited by indomethacin. N ω-nitro-l-arginine methyl ester (l-NAME) and N ω-nitro-l-arginine (l-NNA) inhibited the vasodilation to phenylarsi
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Luk’yanova, V. A., T. S. Papina, A. A. Gimadeev, E. V. Sagadeev та V. P. Barabanov. "Standard formation enthalpies for α-amino acids: L-serine, L-arginine, and L-tyrosine". Moscow University Chemistry Bulletin 66, № 2 (2011): 88–91. http://dx.doi.org/10.3103/s002713141102009x.

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Eroglu, Evren C., Sule Tunug, Omer Faruk Geckil, Umran Kucukgoz Gulec, Mehmet Ali Vardar, and Semra Paydas. "Discovery of metabolomic biomarkers for discriminating platinum-sensitive and platinum-resistant ovarian cancer by using GC-MS." European Journal of Mass Spectrometry 27, no. 6 (2021): 235–48. http://dx.doi.org/10.1177/14690667211057996.

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This study aims to determine ovarian cancer (OC) patients with platinum resistance for alternative treatment protocols by using metabolomic methodologies. Urine and serum samples of platinum-resistant and platinum-sensitive OC were analyzed using GC-MS. After data processing of GC-MS raw data, multivariate analyses were performed to interpret complex data for biologically meaningful information and to identify the biomarkers that cause differences between two groups. The biomarkers were verified after univariate, multivariate, and ROC analysis. Finally, metabolomic pathways related to group se
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Avila, Marcela A., Stacy L. Sell, Yuji Kadoi, et al. "l-Arginine Decreases Fluid-Percussion Injury-Induced Neuronal Nitrotyrosine Immunoreactivity in Rats." Journal of Cerebral Blood Flow & Metabolism 28, no. 10 (2008): 1733–41. http://dx.doi.org/10.1038/jcbfm.2008.66.

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Peroxynitrite is a powerful oxidant capable of nitrating phenolic moieties, such as tyrosine or tyrosine residues in proteins and increases after traumatic brain injury (TBI). First, we tested the hypothesis that TBI increases nitrotyrosine (NT) immunoreactivity in the brain by measuring the number of NT-immunoreactive neurons in the cerebral cortex and hippocampus of rats subjected to parasagittal fluid-percussion TBI. Second, we tested the hypothesis that treatment with l-arginine, a substrate for nitric oxide synthase, further increases NT immunoreactivity over TBI alone. Rats were anesthet
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Žertová, Miroslava, Jiřina Slaninová, and Zdenko Procházka. "Comparison of the Potency of 8-L-Arginine, 8-D-Arginine and 8-D-Homoarginine Vasopressin Analogs with Substituted Phenylalanine in Position 2." Collection of Czechoslovak Chemical Communications 59, no. 6 (1994): 1439–50. http://dx.doi.org/10.1135/cccc19941439.

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An analysis of the uterotonic potencies of all analogs having substituted L- or D-tyrosine or -phenylalanine in position 2 and L-arginine, D-arginine or D-homoarginine in position 8 was made. The series of analogs already published was completed by the solid phase synthesis of ten new analogs having L- or D-Phe, L- or D-Phe(2-Et), L- or D-Phe(2,4,6-triMe) or D-Tyr(Me) in position 2 and either L- or D-arginine in position 8. All newly synthesized analogs were found to be uterotonic inhibitors. Deamination increases both the agonistic and antagonistic potency. In the case of phenylalanine analog
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Kitsiopoulou, Eudoxia, Apostolia A. Hatziefthimiou, Konstantinos I. Gourgoulianis, and Paschalis-Adam Molyvdas. "Resting Tension Affects eNOS Activity in a Calcium-Dependent Way in Airways." Mediators of Inflammation 2007 (2007): 1–6. http://dx.doi.org/10.1155/2007/24174.

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The alteration of resting tension (RT) from 0.5 g to 2.5 g increased significantly airway smooth muscle contractions induced by acetylcholine (ACh) in rabbit trachea. The decrease in extracellular calcium concentration[Ca2+]ofrom 2 mM to 0.2 mM reduced ACh-induced contractions only at 2.5 g RT with no effect at 0.5 g RT. The nonselective inhibitor of nitric oxide synthase (NOS),NG-nitro-L-arginine methyl ester (L-NAME) increased ACh-induced contractions at 2.5 g RT. The inhibitor of inducible NOS, S-methylsothiourea or neuronal NOS, 7-nitroindazole had no effect. At 2.5 g RT, the reduction of[
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Luiking, Yvette C., Marcella M. Hallemeesch, Marcel C. van de Poll, et al. "Reduced citrulline availability by OTC deficiency in mice is related to reduced nitric oxide production." American Journal of Physiology-Endocrinology and Metabolism 295, no. 6 (2008): E1315—E1322. http://dx.doi.org/10.1152/ajpendo.00055.2008.

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The amino acid arginine is the sole precursor for nitric oxide (NO) synthesis. We recently demonstrated that an acute reduction of circulating arginine does not compromise basal or LPS-inducible NO production in mice. In the present study, we investigated the importance of citrulline availability in ornithine transcarbamoylase-deficient spfash (OTCD) mice on NO production, using stable isotope techniques and C57BL6/J (wild-type) mice controls. Plasma amino acids and tracer-to-tracee ratios were measured by LC-MS. NO production was measured as the in vivo conversion of l-[guanidino-15N2]arginin
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Pareddy, D. R., and R. I. Greyson. "Effects of amino acids on the development of spikelets in cultured tassels of Zea mays." Canadian Journal of Botany 67, no. 5 (1989): 1331–35. http://dx.doi.org/10.1139/b89-177.

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The effects of amino acids on spikelet development in in vitro cultured tassels of Zea mays inbred line Oh43 were studied. Single amino acids had differential effects on growth and differentiation of cultured tassels. While a few amino acids (arginine, lysine, valine, and proline) were stimulatory, most of the amino acids were either ineffective (serine, leucine, glycine, threonine, methionine, phenylalanine, histidine, aspartic acid, and tyrosine) or inhibitory (isoleucine, asparagine, tryptophan, glutamic acid, and alanine), at a concentration of 30 mg/L, to the development of "normal" spike
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Seth, A., S. Basuroy, P. Sheth, and R. K. Rao. "l-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer." American Journal of Physiology-Gastrointestinal and Liver Physiology 287, no. 3 (2004): G510—G517. http://dx.doi.org/10.1152/ajpgi.00058.2004.

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Role of l-glutamine in the protection of intestinal epithelium from acetaldehyde-induced disruption of barrier function was evaluated in Caco-2 cell monolayer. l-Glutamine reduced the acetaldehyde-induced decrease in transepithelilal electrical resistance and increase in permeability to inulin and lipopolysaccharide in a time- and dose-dependent manner; d-glutamine, l-aspargine, l-arginine, l-lysine, or l-alanine produced no significant protection. The glutaminase inhibitor 6-diazo-5-oxo-l-norleucine failed to affect the l-glutamine-mediated protection of barrier function. l-Glutamine reduced
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FIROJ, KHAN, and KHAN FARID. "Studies of Coordination Compounds of Cadmium(II) and Zinc(II) with L-Amino Acids as Primary Ligands and Vitamin B6 (Pyridoxine) as Secondary Ligand : A Polarographic Approach." Journal of Indian Chemical Society Vol. 74, Mar 1997 (1997): 171·173. https://doi.org/10.5281/zenodo.5876760.

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Department of Chemistry, Dr. H. S. Gour University, Sagar-470 003 <em>Manuscript received 4 July 1994, revised 28 August 1995, accepted 23 September 1995</em> Polarographic technique has been used to determine the mixed ligand complex formation between Cd<sup>II</sup> and Zn<sup>II</sup> with L-tyrosine, L-arginine, L-methionlne, L-hydroxytryptopbane, L-tryptopbane, L-hydroxyproHne, L-prollne and L-histidine as primary Hgands and vitamin B<sub>6</sub> as a secondary ligands. Cd<sup>II</sup> and Zn<sup>II</sup> formed 1 : 1 : 1, 1 : 1 : 2 and 1 : 2 : 1 complexes. The stability trend of the comp
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Dissertations / Theses on the topic "L-Tyrosine-L-Arginine"

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Ferreira, Soraia Nunes. "Desenvolvimento de novos suportes cromatográficos para purificação do DNA plasmídeo." Master's thesis, 2014. http://hdl.handle.net/10400.6/6098.

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Nos últimos anos, a aplicação de DNA plasmídeo (pDNA) em terapia génica ou vacinas de DNA tem-se revelado uma ferramenta com potencial aplicação no tratamento de inúmeras doenças. Uma vez que esta abordagem recorre a vetores não-virais, é mais segura em termos de ativação de oncogenes e apresenta uma diminuição de reações do sistema imunitário. Deste modo, a indústria farmacêutica procura obter pDNA em maiores quantidades e isento de contaminantes (RNA, DNA genómico, endotoxinas, proteínas). Uma técnica que permite purificar o pDNA é a cromatografia de afinidade (AC). Esta metodologia baseia-s
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