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Journal articles on the topic 'L- Valine and L- Phenylalanine'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Shu, Jingyi, Xinli Zhou, Jixuan Hao, et al. "Terahertz Sensing of L-Valine and L-Phenylalanine Solutions." Sensors 24, no. 12 (2024): 3798. http://dx.doi.org/10.3390/s24123798.

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To detect and differentiate two essential amino acids (L-Valine and L-Phenylalanine) in the human body, a novel asymmetrically folded dual-aperture metal ring terahertz metasurface sensor was designed. A solvent mixture of water and glycerol with a volume ratio of 2:8 was proposed to reduce the absorption of terahertz waves by reducing the water content. A sample chamber with a controlled liquid thickness of 15 μm was fabricated. And a terahertz time-domain spectroscopy (THz-TDS) system, which is capable of horizontally positioning the samples, was assembled. The results of the sensing test re

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2

Nair, K. S., R. G. Schwartz, and S. Welle. "Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans." American Journal of Physiology-Endocrinology and Metabolism 263, no. 5 (1992): E928—E934. http://dx.doi.org/10.1152/ajpendo.1992.263.5.e928.

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Leucine has been proposed as an in vivo regulator of protein metabolism, although the evidence for this in humans remains inconclusive. To test this hypothesis, we infused either L-leucine (154 +/- 1 mumol.kg-1 x h-1) or saline intravenously in six healthy men in two separate studies. L-Leucine infusion increased plasma concentrations of leucine and alpha-ketoisocaproate from 112 +/- 6 and 38 +/- 3 mumol/l to 480 +/- 27 (P < 0.001) and 94 +/- 13 mumol/l (P < 0.001), respectively, without any significant change in circulating insulin or C peptide levels. Leucine infusion decreased plasma

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Treon, Steven P., Mark Hansen, Andrew R. Branagan та ін. "Polymorphisms in FcγRIIIA (CD16) Receptor Expression Are Associated With Clinical Response to Rituximab in Waldenström’s Macroglobulinemia". Journal of Clinical Oncology 23, № 3 (2005): 474–81. http://dx.doi.org/10.1200/jco.2005.06.059.

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Purpose Rituximab is an important therapeutic for Waldenström’s macroglobulinemia (WM). Polymorphisms in FcγRIIIA (CD16) receptor expression modulate human immunoglobulin G1 binding and antibody-dependent cell-mediated cytotoxicity, and may therefore influence responses to rituximab. Patients and Methods Sequence analysis of the entire coding region of FcγRIIIA was undertaken in 58 patients with WM whose outcomes after rituximab were known. Results Variations in five codons of FcγRIIIA were identified. Two were commonly observed (FcγRIIIA-48 and FcγRIIIA-158) and predicted for amino acid polym

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4

Nigg, Herbert N., Rhonda A. Schumann, Jing J. Yang, and Suzanne Fraser. "Consumption of Amino Acid Solutions by Anastrepha suspensa Loew (Diptera: Tephritidae)." Journal of Entomological Science 42, no. 3 (2007): 368–74. http://dx.doi.org/10.18474/0749-8004-42.3.368.

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The consumption of amino acids by Anastrepha suspensa Loew (Caribbean fruit fly) was quantified by measuring individual fly consumption. For no-choice tests, there were no differences in consumption between 0.2 M sucrose and 0.2 M sucrose plus L-alanine, L-glycine, L-histidine, L-phenylalanine, or L-serine solutions. There was increased consumption of 0.05 M L-lysine by 6-d males and of 0.03 M L-valine solutions by 6-d females compared to sucrose alone. Choice tests showed higher consumption of 0.2 M sucrose plus L-lysine, L-valine, and L-glycine, particularly by 6-d-old flies. There was a 3–8

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5

Cortez-Espinosa, Nancy, Judit A. Aviña-Verduzco, Enrique Ramírez-Chávez, Jorge Molina-Torres, and Patricia Ríos-Chávez. "Valine and Phenylalanine as Precursors in the Biosynthesis of Alkamides in Acmella Radicans." Natural Product Communications 6, no. 6 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600625.

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Acmella radicans (Asteraceae) produces at least seven alkamides, most with either an isobutyl- or phenylethyl group as the amine moiety. These moieties suggest that the amino acids valine and phenylalanine are the biosynthetic precursors of these alkamides. On the basis of labeled feeding experiments using either L-[2H8]valine or L-[2H8]phenylalanine we present evidence for the involvement of these two amino acids in the biosynthesis of (2 E,6 Z,8 E)- N-isobutyl-2,6,8-decatrienamide (affinin) (1), (2 Z,4 E)- N-(2-phenylethyl)-2,4-octadienamide (2), (2 E)- N-(2-phenylethyl)-nona-2-en-6,8-diynam

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6

Sobolevsky, Tim G., Alexander I. Revelsky, Igor A. Revelsky, Barbara Miller, and Vincent Oriedo. "Electron Ionization Mass Spectra of N(O,S)-Isobutoxycarbonyl Isobutyl Esters of Amino Acids." European Journal of Mass Spectrometry 8, no. 6 (2002): 447–49. http://dx.doi.org/10.1255/ejms.522.

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Mass spectra of N(O,S)-isobutoxycarbonyl isobutyl esters of 17 amino acids (L-alanine, glycine, L-valine, L-norvaline, L-leucine, L-isoleucine, L-norleucine, L-proline, L-asparagine, L-methionine, L-threonine, L-serine, L-phenylalanine, L-lysine, L-tryptophan, L-tyrosine and L-cystine) were obtained in the electron ionization mode. These derivatives were found suitable for the analysis of amino acids in aqueous media allowing proper identification and quantitation from the mass spectral characteristics.

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7

Ponikwar, Walter, Peter Mayer та Wolfgang Beck. "Metallkomplexe mit biologisch wichtigen Liganden, CXLVI [1]. Bis(allyl)-N,O-α-Aminocarboxylat-Rhodium-Komplexe / Metal Complexes of Biologically Important Ligands, CXLVI [1]. Bis(allyl)-N,O-α-Aminocarboxylate-Rhodium Complexes". Zeitschrift für Naturforschung B 57, № 7 (2002): 810–18. http://dx.doi.org/10.1515/znb-2002-0714.

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The reactions of [(η3-C3H5)2Rh-μ-Cl]2 with the anions of α-amino acids (glycine, L-alanine, L-valine, L-isoleucine, L-proline, L-phenylalanine, L-phenylglycine, L-thyrosine) afford the N,O-chelates (η3-C3H5)2Rh(α-amino carboxylate). For complex (η3-C3H5)2Rh(glycinate) dynamic behaviour in solution could be observed by 1H NMR. The structure of (η3-C3H5)2Rh(L-prolinate) was determined by X-ray diffraction.

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8

PETER, George J., Iain G. DAVIDSON, Aamir AHMED, Lynn McILROY, Alexander R. FORRESTER, and Peter M. TAYLOR. "Multiple components of arginine and phenylalanine transport induced in neutral and basic amino acid transporter-cRNA-injected Xenopus oocytes." Biochemical Journal 318, no. 3 (1996): 915–22. http://dx.doi.org/10.1042/bj3180915.

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The induced uptakes of l-[3H]phenylalanine and l-[3H]arginine in oocytes injected with clonal NBAT (neutral and basic amino acid transporter) cRNA show differential inactivation by pre-treatment with N-ethylmaleimide (NEM), revealing at least two distinct transport processes. NEM-resistant arginine transport is inhibited by leucine and phenylalanine but not by alanine or valine; mutual competitive inhibition of NEM-resistant uptake of arginine and phenylalanine indicates that the two amino acids share a single transporter. NEM-senstive arginine transport is inhibited by leucine, phenylalanine,

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9

Darvas, Zsuzsa, Y. Nozawa, and G. Csaba. "Dissimilar effects of L and D amino acids on the growth of Tetrahymena." Bioscience Reports 7, no. 10 (1987): 757–60. http://dx.doi.org/10.1007/bf01116747.

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Of the L and D configurations of four amino acids (phenylalanine, valine, tryptophan, tyrosine) tested for influence on the growth rate of Tetrahymena, only L-tyrosine was able to induce imprinting in Tetrahymena pyriformis Zeuthen. D-valine stimulated the division of T.pyriformis NT-1, but failed to induce imprinting. The experiments have substantiated the selectivity of the amino acid receptors of Y.pyriformis, and the extraordinary imprinting potential of tyrosine as well, as judged by its influence on the growth rate.

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10

Vasudevan, Paranthaman, and Devaraj Jayaraman. "Synthesis and Characterization of NLO Material L-Valine L-Valinium Perchlorate Monohydrate for Photonics Applications." Photonics Letters of Poland 12, no. 3 (2020): 76. http://dx.doi.org/10.4302/plp.v12i3.1004.

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L-valine L-valinium perchlorate monohydrate single crystal has been synthesized by slow evaporation technique at room temperature. The crystal structure and space group of the crystal were confirmed by single crystal X-ray diffractometer. Optical behavior of the crystal was analyzed by using UV-visible spectrophotometer. Thermal stability was discussed by using thermo gravimetric analysis. Mechanical strength of the grown crystal was studied using Vickers microhardness tester. Nonlinear optical property was explored to confirm the second harmonic generation efficiency of the grown crystal. The

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11

Görbitz, Carl Henrik. "Hydrophobic dipeptides: the final piece in the puzzle." Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 74, no. 3 (2018): 311–18. http://dx.doi.org/10.1107/s2052520618007151.

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The crystal structure of L-valyl-L-leucine acetonitrile solvate presented here adds to 24 previously reported structures of dipeptides constructed from the five nonpolar amino acids L-alanine, L-valine, L-isoleucine, L-leucine and L-phenylalanine. It thus constitutes the final piece in the 5 × 5 puzzle of hydrophobic dipeptide structures. This opportunity is taken to review the crystal packing arrangements and hydrogen-bonding preferences of a rather unique group of substances, with updated information on the various hydrogen-bonding patterns and the associated peptide conformations.

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12

Ohlendorf, Birgit, Sven Simon, Jutta Wiese, and Johannes F. Imhoff. "Szentiamide, an N-formylated Cyclic Depsipeptide from Xenorhabdus szentirmaii DSM 16338T." Natural Product Communications 6, no. 9 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600909.

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Szentiamide (1) a new cyclic hexadepsipeptide was isolated from the culture broth of the entomopathogenic bacterium Xenorhabdus szentirmaii DSM 16338T. The structure was elucidated by analysis of one- and two-dimensional NMR spectra and high resolution mass spectrometry. The amino acids were determined to be D-leucine, L-threonine, D-phenylalanine, D-valine, L-tyrosine and L-tryptophane after hydrolysis and derivatization with D-FDVA [ Nα-(2,4-dinitro-5-fluorophenyl)-D-valinamide].

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13

Pareddy, D. R., and R. I. Greyson. "Effects of amino acids on the development of spikelets in cultured tassels of Zea mays." Canadian Journal of Botany 67, no. 5 (1989): 1331–35. http://dx.doi.org/10.1139/b89-177.

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The effects of amino acids on spikelet development in in vitro cultured tassels of Zea mays inbred line Oh43 were studied. Single amino acids had differential effects on growth and differentiation of cultured tassels. While a few amino acids (arginine, lysine, valine, and proline) were stimulatory, most of the amino acids were either ineffective (serine, leucine, glycine, threonine, methionine, phenylalanine, histidine, aspartic acid, and tyrosine) or inhibitory (isoleucine, asparagine, tryptophan, glutamic acid, and alanine), at a concentration of 30 mg/L, to the development of "normal" spike

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14

Shail Pande, Shakti K. Prabhuji ,., and Atul K. Srivastava. "CERTAIN AMINO ACIDS ARE POTENT FISH-FUNGICIDES." Journal Of Advanced Zoology 41, no. 01 (2021): 27–31. http://dx.doi.org/10.17762/jaz.v41i01.16.

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The potential fungicidal abilities of L-cysteine, L-valine, L-phenylalanine, L-methionine, L-alanine and L-isoleucine have been tested in vitro on five fish pathogenic watermoulds, four of Saprolegniaceae, viz., Achlya orion Coker & Couch, Aphanomyces laevis deBary, Dictyuchus sterile Coker, Saprolegnia diclina Humphrey; and one Blastocladiaceae, viz., Allomyces arbuscula Butler. The lowest concentration having fungicidal ability has been found to be 0.25%. Tolerance tests have also been conducted using Colisa lalius Hamilton and Channa punctata Bloch as test fishes and 0.25% has been reco

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15

White, J. F. "Primary culture of salamander intestinal epithelial cells from nests: whole cell Na+ currents induced by valine." American Journal of Physiology-Gastrointestinal and Liver Physiology 267, no. 1 (1994): G59—G66. http://dx.doi.org/10.1152/ajpgi.1994.267.1.g59.

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Methods are described for isolating the cell nests, subepithelial clusters of germinative cells, from salamander intestinal mucosa and for growing the nests in culture into polarized monolayers of intestinal epithelial cells. Cells were viable in culture for up to 3 wk. The capacity of the monolayer cells to engage in membrane transport was evaluated using the patch-clamp technique in the whole cell mode. L-Valine (25 mM) induced an inward current in small intestinal cells of 25.8 +/- 5.7 pA and depolarized the cell membrane 14.5 +/- 1.6 mV. L-Alanine and L-phenylalanine were similarly effecti

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16

Huang, Qin, Hou-Jin Li, Chang-Bai Huang, Zi-Han Wang, Wen-Jian Lan, and Lai-You Wang. "Alkaloids From the Marine Fungus Lecanicillium fusisporum Using an Amino Acid-Directed Strategy." Natural Product Communications 16, no. 10 (2021): 1934578X2110460. http://dx.doi.org/10.1177/1934578x211046072.

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An amino acid-directed strategy has been developed to explore the potential of marine fungi to produce alkaloids. The marine fungus Lecanicillium fusisporum was cultured in glucose-peptone-yeast (GPY) medium to which were added L-tryptophan, L-phenylalanine, L-threonine, D, L-methionine, L-serine, L-lysine and L-valine. A new indole alkaloid, lecasporinoid (1), along with five known alkaloids (2−6) were discovered from the culture broth. The planar structure of lecasporinoid (1) was determined by HR-ESIMS, and 1D and 2D NMR spectroscopic data. The absolute configuration was established by opti

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17

Zhao, Xinyi, Hongge Jia, Qingji Wang, et al. "The oxidative coupling between benzaldehyde derivatives and phenylacetylene catalyzed by rhodium complexes via C-H bond activation." Heterocyclic Communications 26, no. 1 (2020): 20–25. http://dx.doi.org/10.1515/hc-2020-0004.

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AbstractThis paper reports the use of rhodium (Rh) catalysts for the oxidative coupling reaction between phenylacetylene and benzaldehyde derivatives via C-H bond activation. These reactions were catalyzed by Rh(l-amino acid)(cod) (the l-amino acid is l-phenylalanine, l-valine or l-proline; cod is 1,5-cyclooctadiene) to obtain chromones in 12.7–88.3% yield. These new Rh catalysts have excellent activity for the coupling reaction between phenylacetylene and different benzaldehyde derivatives. It was found that the electronic effects of the benzaldehyde derivative substituent affected the reacti

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18

Sechin, Evgeniy Nikolaevich, Oleg Anatolyevich Marakaev, and Gavriil Borisovich Gavrilov. "AMINO ACID COMPOSITION OF VEGETATIVE ORGANS DACTYLORHIZA MACULATA (L.) SOÓ (ORCHIDACEAE)." chemistry of plant raw material, no. 2 (January 23, 2019): 135–43. http://dx.doi.org/10.14258/jcprm.2019024364.

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Amino acid composition of aboveground and underground vegetative organs of Dactylorhiza maculata (L.) Soó (Orchidaceae), one of the representatives of the tuberoid species of orchids growing under the natural conditions of the center of European Russia, was detected using the method of zone capillary electrophoresis. The presence of 15 amino acids in the plant material, nine of them are «essential» (lysine, phenylalanine, histidine, leucine, isoleucine, methionine, valine, threonine, tryptophan) was established. The highest total amino acid content is characteristic of the leaves, the smallest

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Tanaka, Mikiei, Yasuo Mukohata, and Seiji Yuasa. "Utilization of D-amino acids by Halobacterium halobium R1mR." Canadian Journal of Microbiology 35, no. 4 (1989): 508–11. http://dx.doi.org/10.1139/m89-078.

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Halobacterium halobium R1mR required L-amino acids such as methionine, leucine, valine, isoleucine, arginine, and lysine for growth. They also grew, with a lag phase of 15 to 20 days, when phenylalanine or tyrosine was omitted from the medium. This represents the first evidence that halophilic bacteria can grow on either D-methionine, D-phenylalanine, D-tyrosine, or D-leucine, each of which was substituted for the opposite enantiomer in the medium.Key words: halobacteria, D-amino acid.

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McNurlan, M. A., P. Essen, S. D. Heys, V. Buchan, P. J. Garlick, and J. Wernerman. "Measurement of protein synthesis in human skeletal muscle: further investigation of the flooding technique." Clinical Science 81, s25 (1991): 557–64. http://dx.doi.org/10.1042/cs0810557.

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1. The rate of protein synthesis in quadriceps muscle of healthy subjects estimated from the incorporation of l-[1-13C]leucine given by continuous infusion was 1.1%/day. The estimate of protein synthesis from the incorporation of a flooding amount of labelled leucine was 1.8%/day (sd 0.65). The possibility that the higher rate obtained with the flooding technique arose from stimulation of protein synthesis by the large amount of leucine is unlikely. 2. The same rate of protein synthesis (1.7%/day, sd 0.3) was obtained with a flooding amount (0.05 g/kg) of a different amino acid, l-[1-13C]pheny

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21

Valls, Adriana, Jose J. Andreu, Eva Falomir, et al. "Imidazole and Imidazolium Antibacterial Drugs Derived from Amino Acids." Pharmaceuticals 13, no. 12 (2020): 482. http://dx.doi.org/10.3390/ph13120482.

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The antibacterial activity of imidazole and imidazolium salts is highly dependent upon their lipophilicity, which can be tuned through the introduction of different hydrophobic substituents on the nitrogen atoms of the imidazole or imidazolium ring of the molecule. Taking this into consideration, we have synthesized and characterized a series of imidazole and imidazolium salts derived from L-valine and L-phenylalanine containing different hydrophobic groups and tested their antibacterial activity against two model bacterial strains, Gram-negative E. coli and Gram-positive B. subtilis. Importan

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22

Nallini, A., K. Saraboji, M. N. Ponnuswamy, and S. B. Katti. "Structure and conformation of n- (t-butoxycarbonyl)-l-valine-l-phenylalanine-methyl ester (Boc-Val-Phe-OMe)." Crystal Research and Technology 39, no. 2 (2004): 179–84. http://dx.doi.org/10.1002/crat.200310168.

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23

Lippi, Ilaria, Francesca Perondi, Alessio Pierini, et al. "Essential and Non-Essential Amino Acids in Dogs at Different Stages of Chronic Kidney Disease." Veterinary Sciences 9, no. 7 (2022): 331. http://dx.doi.org/10.3390/vetsci9070331.

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Abnormalities of serum amino acid profile, mostly characterized by a reduction in essential amino acids (EAAs) and an increase in non-essential amino acids (NEAAs), have been documented in human chronic kidney diseases (CKD). Amino acid disorders have been associated with CKD complications, such as metabolic acidosis and malnutrition. The aim of the present study was to evaluate EAAs and NEAAs in dogs affected by CKD at different IRIS stages, with particular reference to calcium–phosphate abnormalities, metabolic acidosis, and protein-energy wasting syndrome (PEW). Serum EAAs (L-histidine, L-i

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Marcovecchio, M. Loredana, Barry Widmer, David B. Dunger, and R. Neil Dalton. "Effect of acute variations of insulin and glucose on plasma concentrations of asymmetric dimethylarginine in young people with Type 1 diabetes." Clinical Science 115, no. 12 (2008): 361–69. http://dx.doi.org/10.1042/cs20080079.

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ADMA (asymmetric dimethylarginine), an endogenous inhibitor of nitric oxide synthase, is considered a major risk factor for cardiovascular disease and progression of renal disease. In the present study we aim to investigate the effect of acute variations in plasma glucose and insulin on plasma ADMA levels in young people with T1D (Type 1 diabetes). Fifteen young patients (ten males) with T1D, median age 18.3 (13.2–24.4) years, HbA1c (glycated haemoglobin) 9% (6.4–13.6%), underwent an overnight (18:00–08:00 hours) variable insulin infusion for euglycaemia, followed by a hyperinsulinaemic–euglyc

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Marienhagen, Jan, Nicole Kennerknecht, Hermann Sahm, and Lothar Eggeling. "Functional Analysis of All Aminotransferase Proteins Inferred from the Genome Sequence of Corynebacterium glutamicum." Journal of Bacteriology 187, no. 22 (2005): 7639–46. http://dx.doi.org/10.1128/jb.187.22.7639-7646.2005.

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ABSTRACT Twenty putative aminotransferase (AT) proteins of Corynebacterium glutamicum, or rather pyridoxal-5′-phosphate (PLP)-dependent enzymes, were isolated and assayed among others with l-glutamate, l-aspartate, and l-alanine as amino donors and a number of 2-oxo-acids as amino acceptors. One outstanding AT identified is AlaT, which has a broad amino donor specificity utilizing (in the order of preference) l-glutamate > 2-aminobutyrate > l-aspartate with pyruvate as acceptor. Another AT is AvtA, which utilizes l-alanine to aminate 2-oxo-isovalerate, the l-valine precursor, and 2-oxo-b

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Lodwig, Siegfried N., та Clifford J. Unkefer. "Stereoselective synthesis of stable isotope-labeled L-α-amino acids: Electrophilic amination of Oppolzer's acyl sultams in the synthesis of L-[15N]alanine, L-[15N]valine, L-[15N]leucine, L-[15N]phenylalanine and L-[1-13C, 15N]valine". Journal of Labelled Compounds and Radiopharmaceuticals 38, № 3 (1996): 239–48. http://dx.doi.org/10.1002/(sici)1099-1344(199603)38:3<239::aid-jlcr831>3.0.co;2-e.

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Skibniewska, K. A., J. Zakrzewski, J. Kłobukowski, et al. "Nutritional value of the protein of consumer carp Cyprinus carpio L." Czech Journal of Food Sciences 31, No. 4 (2013): 313–17. http://dx.doi.org/10.17221/337/2012-cjfs.

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The nutritional value of the protein of carp from breeding technologies currently employed in Poland (semi-extensive, low-intensive and high-intensive ones) was evaluated. The total protein content was from 16.9% to 18.6% and did not diverge from the content of this nutrient in other fish species. The protein of the studied carps was characterised by a high content of exogenous amino acids, considerably exceeding their amount compared to the standard protein, irrespective of the area of breeding or the production intensity level. The dominant amino acids were histidine, methionine, and cystein

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Facchin, Gianella, María H. Torre, Eduardo Kremer, Oscar E. Piro, Eduardo E. Castellano, and Enrique J. Baran. "Structural and Spectroscopic Characterization of Two New Cu(II)-Dipeptide Complexes." Zeitschrift für Naturforschung B 55, no. 12 (2000): 1157–62. http://dx.doi.org/10.1515/znb-2000-1209.

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Two new Cu(II) complexes of stoichiometry [Cu(L-dipept)], containing as ligands the dipeptides L-alanine-L-valine and L-alanine-L-phenylalanine were prepared. They were characterized by single crystal X-ray diffractometry, and infrared and electronic spectroscopy. Both crystallize in the orthorhombic space group P212121 with Z = 4. The Cu(II) ion has essentially the same elongated pyramidal coordination, being equatorially cis coordinated by a N2O2 arrangement of ligand atoms and axially by a carbonyl oxygen atom. The compounds show rather similar polymeric structures that differ from each oth

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29

Fairushina, A. I., S. F. Petrova, and L. A. Baltina. "Selective Synthesis of Amino Acid Conjugates of Glycyrrhizic Acid Using N-Oxyphthalimide and N,N′-Dicyclohexylcarbodiimide." Žurnal obŝej himii 94, no. 7 (2024): 815–22. https://doi.org/10.31857/s0044460x24070035.

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A selective synthesis of amino acid conjugates of glycyrrhizic acid containing amino acid residues in the carbohydrate part of the glycoside was proposed using N-oxyphthalimide (HOPt) and N,N′-dicyclohexylcarbodiimide (DCC), tert-butyl and benzyl/4-nitrobenzyl esters of L-amino acids with yields of 55–60%. Free conjugates of glycyrrhizic acid with valine, isoleucine, methionine, phenylalanine, leucine, tyrosine and glutamic acid were obtained by deblocking the ester groups.

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Sun, Luning, Huiwen Jiao, Beibei Gao, et al. "Hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry method for the simultaneous determination of l -valine, l -l eucine, l -isoleucine, l -phenylalanine, and l -tyrosine in human serum." Journal of Separation Science 38, no. 22 (2015): 3876–83. http://dx.doi.org/10.1002/jssc.201500512.

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Kanazawa, Hitoshi, and Yuji Ohashi. "Polymerization of N-Carboxy Anhydrides of L- and DL- Valine, and L- and DL- Phenylalanine in the Solid State." Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals 277, no. 1 (1996): 45–54. http://dx.doi.org/10.1080/10587259608046002.

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Deng, Chaoyang, Yang Yue, Hefei Zhang, et al. "Serum Metabolomics and Ionomics Analysis of Hoof-Deformed Cows Based on LC-MS/MS and ICP-OES/MS." Animals 13, no. 9 (2023): 1440. http://dx.doi.org/10.3390/ani13091440.

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In order to explore the metabolic and ionic changes of hoof-deformed cows, the serum samples of 10 healthy cows (group C) and 10 hoof-deformed cows (group T) were analyzed by LC-MS/MS and ICP-OES/MS. The pathway enrichment of differential metabolites was analyzed by screening and identifying differential metabolites and ions and using a bioinformatics method. The integration of metabolomics and ionics was analyzed with ggplot2 software in R language, and verified by MRM target metabolomics. The results showed that 127 metabolites were screened by metabolomics, of which 81 were up-regulated (p

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Ott, Linda G., Jack J. Schmidt, A. Byron Young, et al. "Comparison of Administration of Two Standard Intravenous Amino Acid Formulas to Severely Brain-Injured Patients." Drug Intelligence & Clinical Pharmacy 22, no. 10 (1988): 763–68. http://dx.doi.org/10.1177/106002808802201004.

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Twenty severely brain-injured patients with Glasgow Coma Scale scores of 4–9 were prospectively randomized to receive one of two standard amino acid formulas, starting with the first day of hospital admission up to day 14 postinjury. Formula 2 (patient group 2) had 54 percent more leucine, 53 percent more isoleucine, 74 percent more valine, 28 percent less phenylalanine, 31 percent less methionine, 111 percent more proline, 38 percent less alanine, and 38 percent less glycine than formula 1 (patient group 1). Groups 1 and 2 received statistically equal overall mean parenteral nutrition calorie

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Cui, Mengni, Alessia Trimigno, Josue L. Castro-Mejía, et al. "Human Fecal Metabolome Reflects Differences in Body Mass Index, Physical Fitness, and Blood Lipoproteins in Healthy Older Adults." Metabolites 11, no. 11 (2021): 717. http://dx.doi.org/10.3390/metabo11110717.

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This study investigated how body mass index (BMI), physical fitness, and blood plasma lipoprotein levels are related to the fecal metabolome in older adults. The fecal metabolome data were acquired using proton nuclear magnetic resonance spectroscopy and gas chromatography–mass spectrometry on 163 healthy older adults (65–80 years old, 80 females and 83 males). Overweight and obese subjects (BMI ≥ 27) showed higher levels of fecal amino acids (AAs) (valine, alanine, and phenylalanine) compared to normal-weight subjects (BMI ≤ 23.5). Adults classified in the high-fitness group displayed slightl

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Miroslaw, Barbara, Oleg M. Demchuk, Roman Luboradzki, and Katarzyna Tyszczuk-Rotko. "Low-Molecular-Weight Organogelators Based on N-dodecanoyl-L-amino Acids—Energy Frameworks and Supramolecular Synthons." Materials 16, no. 2 (2023): 702. http://dx.doi.org/10.3390/ma16020702.

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Lauric acid was used to synthesize the low-molecular-weight organogelators (LMOGs), derivatives of two endogenous (L)-alanine, (L)-leucine, and three exogenous (L)-valine, (L)-phenylalanine, and (L)-proline amino acids. The nature of processes responsible for the gel formation both in polar and in apolar solvents of such compounds is still under investigation. Knowing that the organization of surfactant molecules affects the properties of nano scale materials and gels, we decided to elucidate this problem using crystallographic diffraction and energy frameworks analysis. The single crystals of

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Maune, Matthew W., and Ralph S. Tanner. "Description of Anaerobaculum hydrogeniformans sp. nov., an anaerobe that produces hydrogen from glucose, and emended description of the genus Anaerobaculum." International Journal of Systematic and Evolutionary Microbiology 62, Pt_4 (2012): 832–38. http://dx.doi.org/10.1099/ijs.0.024349-0.

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A novel anaerobic, moderately thermophilic, NaCl-requiring fermentative bacterium, strain OS1T, was isolated from oil production water collected from Alaska, USA. Cells were Gram-negative, non-motile, non-spore-forming rods (1.7–2.7 × 0.4–0.5 µm). The G+C content of the genomic DNA of strain OS1T was 46.6 mol%. The optimum temperature, pH and NaCl concentration for growth of strain OS1T were 55 °C, pH 7 and 10 g l−1, respectively. The bacterium fermented d-fructose, d-glucose, maltose, d-mannose, α-ketoglutarate, l-glutamate, malonate, pyruvate, l-tartrate, l-asparagine, Casamino acids, l-cyst

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Deng, Chunhui, and Yonghui Deng. "Diagnosis of maple syrup urine disease by determination of l-valine, l-isoleucine, l-leucine and l-phenylalanine in neonatal blood spots by gas chromatography–mass spectrometry." Journal of Chromatography B 792, no. 2 (2003): 261–68. http://dx.doi.org/10.1016/s1570-0232(03)00270-8.

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Yang, Yulong, Qi Yu, Ruonan Zhou, et al. "Occurrence of Free Amino Acids in the Source Waters of Zhejiang Province, China, and Their Removal and Transformation in Drinking Water Systems." Water 12, no. 1 (2019): 73. http://dx.doi.org/10.3390/w12010073.

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Free amino acids (FAAs) are key components of the global nitrogen cycle and important disinfection byproduct (DBP) precursors. The knowledge gap of FAA occurrence in source and engineered water is discussed in this paper. Solid phase extraction and post column derivatization was combined with gas chromatography–mass spectrometry to simultaneously detect μg/L concentrations of FAAs. This method efficiently detects alanine (Ala), threonine (Thr), serine (Ser), valine (Val), leucine (Leu), isoleucine (Ile), proline (Pro), aspartic (Asp), phenylalanine (Phe), and glutamic acid (Glu) with good line

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Koshovyi, Oleh, Ain Raal, Igor Kireyev, et al. "Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts." Plants 10, no. 2 (2021): 230. http://dx.doi.org/10.3390/plants10020230.

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The prospect of creating a new medicine with psychotropic activity is shown as a result of studying the chemical composition and pharmacological activity of modified dry extracts of motherwort (Leonurus cardiaca L.) tincture. The most promising substances were the dry extracts, modified by adding small amounts of arginine, valine, phenylalanine, glycine, lysine, and alanine. A total of 15 main phenolic substances were found in the extracts, and eight of them were identified. There were also 10 hydroxycinnamic acids in these extracts, three of which were identified (chlorogenic, caffeic, and ro

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FU, Shan-Lin, and Roger T. DEAN. "Structural characterization of the products of hydroxyl-radical damage to leucine and their detection on proteins." Biochemical Journal 324, no. 1 (1997): 41–48. http://dx.doi.org/10.1042/bj3240041.

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We have previously reported the formation of valine hydroperoxides and aldehydes from hydroxyl-radical attack on free valine and protein molecules. We have also demonstrated that the major degradation products of valine hydroperoxides by several biochemical and cellular systems are the corresponding hydroxides, and therefore proposed that hydroxyvalines may serve as useful in vivo markers for studying protein oxidation. Here we have undertaken the structural elucidation of the oxidation products of leucine, another amino acid which is very susceptible to peroxidation. Hydroxyl-radical (HO•) at

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Voronina, Oksana A. "The level of copper in the milk of breeding cows in winter and spring." Veterinariya, Zootekhniya i Biotekhnologiya 12/1, no. 107 (2022): 112–16. http://dx.doi.org/10.36871/vet.zoo.bio.202212114.

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As an essential test for all forms of life on earth, copper (Cu) is of great interest and a vast field for research. The inclusion of Cu in the functioning of a group of substances is carried out through amino acids. The scope of action of copper-containing proteins is quite wide. They are involved in the accumulation of blood cells and the functioning of the immune system, include increased lipid content, contraction of the cardiovascular system and body growth. The purpose of this work is to follow the dynamics of the Cu content in milk at the time of the season change and to establish the s

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Sloun, Bart van, Gijs H. Goossens, Balazs Erdos, Michael Lenz, Natal van Riel, and Ilja C. W. Arts. "The Impact of Amino Acids on Postprandial Glucose and Insulin Kinetics in Humans: A Quantitative Overview." Nutrients 12, no. 10 (2020): 3211. http://dx.doi.org/10.3390/nu12103211.

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Different amino acids (AAs) may exert distinct effects on postprandial glucose and insulin concentrations. A quantitative comparison of the effects of AAs on glucose and insulin kinetics in humans is currently lacking. PubMed was queried to identify intervention studies reporting glucose and insulin concentrations after acute ingestion and/or intravenous infusion of AAs in healthy adults and those living with obesity and/or type 2 diabetes (T2DM). The systematic literature search identified 55 studies that examined the effects of l-leucine, l-isoleucine, l-alanine, l-glutamine, l-arginine, l-l

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Darvish, M., S. A. Ebrahimi, and P. Ghadam. "Development of Micellar Electro Kinetic Chromatography for the Separation and Quantitation of L-valine, L-leucine, L-isoleucin and L-phenylalanine in Human Plasma and Comparison with HPLC." Pakistan Journal of Biological Sciences 10, no. 15 (2007): 2436–41. http://dx.doi.org/10.3923/pjbs.2007.2436.2441.

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Sotelo, C. G., J. M. Franco, S. P. Aubourg, and J. M. Gallardo. "Changes in free amino acids of hake (Merluccius merluccius L.) muscle during frozen storage/Cambios producidos en los aminoácidos libres del músculo de merluza (Merluccius merluccius L.) durante su conservación en estado congelado." Food Science and Technology International 1, no. 1 (1995): 19–24. http://dx.doi.org/10.1177/108201329500100103.

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The effect of storage at subzero temperatures (-5°C, -12°C, and -20°C) on hake ( Merluccius merluccius L.) muscle free-amino acid fraction was evaluated. A significant increase in free aspartic acid, serine, threonine, arginine, β-alanine, tyrosine, methionine, valine, phenylalanine, isoleucine, leucine, and lysine was found at -5°C, whereas at -12°C, a significant decrease in free glutamic acid, glycine, methyl-histidine, β-alanine, taurine, alanine, and leucine was the most noticeable. No changes in the free amino acid fraction were observed at -20°C. Activity of different kind of enzymes, a

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45

M., Sivasankaran Nair, and Theodore David Manickam S. "Schiff base complex formation by cobalt(II) and nickel(II) with 2-pyridine-carboxaldehyde and some bidentate amino acids." Journal of Indian Chemical Society Vol. 76, Oct 1999 (1999): 472–74. https://doi.org/10.5281/zenodo.5860750.

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Department of Chemistry, Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli-627 012, India Department of Chemistry, St. John's College, Tirunelveli-627 002, India <em>Manuscript received 10 February 1999. revised 10 May 1999, accepted 23 June 1999</em> MAB, MA<sub>2</sub>B and MA<sub>2</sub>B<sub>2</sub> types of Schiff base complexes have been detected in the Co<sup>II</sup>- and Ni<sup>II</sup>-2-pyridinecarboxaldehyde (A)-L-valine, -L-phenylalanine and -DL-tryptophan (B) systems. Both the stability constant and absorption maximum values indicate that these complexes can be re

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46

Broge, J. M., and D. L. Leussing. "Mechanism of the reversed-phase high-performance liquid chromatographic separation of D- and L-valine using copper(II) and L-aspartyl-L-phenylalanine methyl ester." Analytical Chemistry 58, no. 11 (1986): 2237–41. http://dx.doi.org/10.1021/ac00124a026.

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Воронов (Voronov), Иван (Ivan) Васильевич (Vasil'evich). "AMINO-ACID COMPOSITION OF ATRIPLEX PATULA L. AND AMARANTHUS RETROFLEXUS L. (AMARANTHACE-AE) GROWING IN CENTRAL YAKUTIA." chemistry of plant raw material, no. 3 (February 15, 2018): 69–74. http://dx.doi.org/10.14258/jcprm.2018033610.

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The research goal is comparative study the amino acid composition of seeds and leaves of Atriplex patula L. and Amaranthus retroflexus L. from the flora of Central Yakutia (the Republic of Sakha (Yakutia). Leaves and seeds of A. patula and A. retroflexus were sampled in August 2016 in the fruiting phase. Biochemical and amino acid composition, the content of crude protein, fat, calcium and phosphorus of the abovementioned plants was studied at the premises of the State budgetary institution of the Republic of Sakha (Yakutia) "Yakut Republican Veterinary Testing Laboratory". From 14 studied ami

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Ahmad, Homsi, and Kasideh Amer. "Synthesis of some N-phthalimide derivatives and Evaluation their Biological Activity." Pharmaceutical and Chemical Journal 2, no. 3 (2015): 33–41. https://doi.org/10.5281/zenodo.13730096.

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In this research six of N-phthalimides of amino acids (<strong>IIIa-f)</strong> have been synthesized, as a first step, through cyclocondensation of o-phthalic acid with amino acids (glycine, L-alanine, L-valine, L-leucine, L-phenylalanine, L-aspartic) in the presence of glacial acetic acid in bath oil (170-180 <sup>o</sup>C), the results of this step were compared with the results of traditional method. In the second step, (<strong>IIIa-b) </strong>were refluxed with <em>o</em>-phenylene diamine (I<strong>Va</strong>) in the present of (HCl, 4N) for 2 h to give <em>N</em>-(1<em>H</em>-benzimi

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Slominski, A., G. Moellmann, E. Kuklinska, A. Bomirski, and J. Pawelek. "Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, L-tyrosine and L-dopa." Journal of Cell Science 89, no. 3 (1988): 287–96. http://dx.doi.org/10.1242/jcs.89.3.287.

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We describe results demonstrating the positive regulation of melanogenesis by two substrates of the melanogenic pathway. We have found that L-tyrosine and L-dihydroxyphenylalanine (L-dopa), whose metabolic fates are affected by the activity of that pathway, can also act as its regulators. In living pigment cells, tyrosinase (EC 1.14.18.1), a crucial and rate-limiting enzyme of melanogenesis, acts in subcellular organelles known as melanosomes. Melanin is laid down only in these organelles. We demonstrate that supplementing Ham's F-10 medium with additional L-tyrosine or L-dopa during the cultu

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Dr., Yasmin Akhtar. "INTERACTION STUDIES OF AMINO ACIDS IN AQUEOUS SODIUM BROMIDE SOLUTIONS AT DIFFERENT TEMPERATURE." International Journal of Research - Granthaalayah 5, no. 10 (2017): 160–67. https://doi.org/10.5281/zenodo.1040272.

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Densities, ultrasonic velocities and viscosities of L- Valine and L- Phenylalanine in aqueous sodium bromide (0.00, 0.025 and 0.05) m solutions have been determined experimentally at 308 and 313 K. The results obtained from density ultrasonic velocity and viscosity measurement have been used to calculate the apparent molal volume, ф<sub>v</sub>, apparent molal, adiabatic compressibility ф <sub>Ks</sub>, partial molal volume ф<sup>0</sup><sub>v</sub> at infinite dilution, partial molal adiabatic compressibility ф<sup>0</sup><sub>Ks</sub> at infinite dilution, transfer volume ∆ф<sub>(tr)</sub>,

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