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Journal articles on the topic 'Lab Notebook'

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1

Kim, Dong-Jin, Kuk-Tae Park, and Denise Pentland. "Correlations between Chemistry Lab Notebooks Scores and Academic Achievement Scores of Gifted Science Students and Their Perceptions on Chemistry Lab and the Lab Notebooks." INTERNATIONAL JOURNAL OF RESEARCH IN EDUCATION METHODOLOGY 6, no. 2 (2015): 875–86. http://dx.doi.org/10.24297/ijrem.v6i2.3883.

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The purpose of this study is to analyze chemistry laboratory notebooks completed by gifted science students and their observations on chemistry experiments and the laboratory notebooks, focusing on the correlations among the students’ mid-term academic achievement (MAA) scores, the holistic grading scale (HGS) and lab note rubric (LNR) scores for their chemistry laboratory notebooks. Through an e-mail questionnaire, the gifted science students, now attending universities, gave their opinion on the value of the chemistry experiments and the laboratory notebooks they wrote in their high school
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McCartney, M. "Follow scientists, not the lab notebook." Science 346, no. 6212 (2014): 961. http://dx.doi.org/10.1126/science.346.6212.961-g.

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Ghannam, Rami. "Do You Call That a Lab Notebook?" IEEE Potentials 39, no. 5 (2020): 21–24. http://dx.doi.org/10.1109/mpot.2020.2968798.

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Yeston, J. "Beyond blank slates in the lab notebook." Science 351, no. 6279 (2016): 1277–78. http://dx.doi.org/10.1126/science.351.6279.1277-e.

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Saito, Shigeyoshi. "4. How to Keep a Lab Notebook." Japanese Journal of Radiological Technology 75, no. 8 (2019): 825–31. http://dx.doi.org/10.6009/jjrt.2019_jsrt_75.8.825.

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Goddard, Nigel H., Rory Macneil, and Jonathan Ritchie. "eCAT: Online electronic lab notebook for scientific research." Automated Experimentation 1, no. 1 (2009): 4. http://dx.doi.org/10.1186/1759-4499-1-4.

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Rees, Ian, Ed Langley, Wah Chiu, and Steven J. Ludtke. "EMEN2: An Object Oriented Database and Electronic Lab Notebook." Microscopy and Microanalysis 19, no. 1 (2013): 1–10. http://dx.doi.org/10.1017/s1431927612014043.

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AbstractTransmission electron microscopy and associated methods, such as single particle analysis, two-dimensional crystallography, helical reconstruction, and tomography, are highly data-intensive experimental sciences, which also have substantial variability in experimental technique. Object-oriented databases present an attractive alternative to traditional relational databases for situations where the experiments themselves are continually evolving. We present EMEN2, an easy to use object-oriented database with a highly flexible infrastructure originally targeted for transmission electron
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Uieda, Leonardo, Vanderlei C. Oliveira, and Valéria C. F. Barbosa. "Geophysical tutorial: Euler deconvolution of potential-field data." Leading Edge 33, no. 4 (2014): 448–50. http://dx.doi.org/10.1190/tle33040448.1.

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In this tutorial, we will talk about a widely used method of interpretation for potential-field data called Euler de-convolution. Our goal is to demonstrate its usefulness and, most important, to call attention to some pitfalls encountered in interpretation of the results. The code and synthetic data required to reproduce our results and figures can be found in the accompanying IPython notebooks ( ipython.org/notebook ) at dx.doi.org/10.6084/m9.figshare.923450 or github.com/pinga-lab/paper-tle-euler-tutorial . The note-books also expand the analysis presented here. We encourage you to download
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Marecki, Piotr. "Between Provocation and Experiment. Technical Reports and the Ecology of Scholarly Communication in the Humanities." Kultura i Edukacja 110, no. 4 (2015): 169–81. http://dx.doi.org/10.15804/kie.2015.04.10.

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The aim of this paper is to describe a genre that is gaining importance in contemporary humanities, and especially in its areas devoted to digital media – the technical report. Technical reports are discussed as part of the larger trend of open notebook science. This form of communication draws from experiences worked out in the field of technology, computer science and science. In this understanding technical reports are a genre of gray literature, a form dedicated to communicating results of research projects conducted by laboratories. The case study discussed in this text is devoted to a se
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Claar, Danielle C., Armand Kuris, Katie L. Leslie, Rachel L. Welicky, Maureen A. Williams, and Chelsea L. Wood. "Parasite Biodiversity: Fish Dissection and Assays for Parasites." Lessons in Conservation 11 (2021): 58–67. https://doi.org/10.5531/cbc.linc.11.1.6.

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This exercise is a wet lab that involves dissecting an easy (and disturbing) source of live parasite material: fresh fish from your local seafood market. Students will search for both ectoparasites (on the outside of the host) and endoparasites (inside the tissues of the host). They will create a lab notebook entry, and they will also discuss observations of parasites within their fish and patterns among other fish dissected in the class.
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Shimamoto, Tetsuo. "Encouragement of the Electronic Lab-Notebook for the Organic Chemist." Journal of Synthetic Organic Chemistry, Japan 75, no. 8 (2017): 866–71. http://dx.doi.org/10.5059/yukigoseikyokaishi.75.866.

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Coles, Simon, Graham Tizzard, and Jan Kuras. "Opening up the Lab Notebook: Publishing Experimental & Supplementary Information." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C1690. http://dx.doi.org/10.1107/s2053273314083090.

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Supplementary Information supporting publications is not uniform across journals, is generally not 100% representative of the work undertaken, is not structured or comprehensive and therefore is often not fully considered in review. In chemistry articles where characterisation techniques are applied widely, crystallography is the exception in that there are universally agreed processes and protocols for presenting the scientific findings and the supporting data. Crystallography can therefore lead the way! Our approach to solving the broader problem of availability of supporting information is
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Arnstein, Larry, Stefan Sigdursson, and Bob Franza. "Ubiquitous Computing in the Biology Laboratory." JALA: Journal of the Association for Laboratory Automation 6, no. 1 (2001): 66–67. http://dx.doi.org/10.1016/s1535-5535-04-00119-4.

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Our objective is to eliminate the digital divide that persists between the physical and information spaces of wet-lab based enterprises by embedding computational resources into the shared laboratory environment. Our first challenge is to enable individual lab workers to contribute to a fine-grained formal representation of ongoing lab activities — to build the database by doing the work, without having to stop and write things down in a notebook or to enter information into a computer. By eliminating the redundancy of doing the work and then recording it, accuracy and completeness will be imp
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Rahn, Jennifer, Dana Willner, James Deverick, Peter Kemper, and Margaret Saha. "Incorporating Computer Programming & Data Science into a Guided Inquiry-Based Undergraduate Ecology Lab." American Biology Teacher 81, no. 9 (2019): 649–57. http://dx.doi.org/10.1525/abt.2019.81.9.649.

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The biological sciences are becoming increasingly reliant on computer science and associated technologies to quickly and efficiently analyze and interpret complex data sets. Introducing students to data analysis techniques is a critical part of their development as well-rounded, scientifically literate citizens. As part of a collaborative effort between the Biology and Computer Science departments at William & Mary, we sought to develop laboratory exercises that would introduce basic ideas of data analysis while also exposing students to Python, a commonly used computer programming languag
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Gubler, Hanspeter, Nicholas Clare, Laurent Galafassi, Uwe Geissler, Michel Girod, and Guy Herr. "Helios: History and Anatomy of a Successful In-House Enterprise High-Throughput Screening and Profiling Data Analysis System." SLAS DISCOVERY: Advancing the Science of Drug Discovery 23, no. 5 (2018): 474–88. http://dx.doi.org/10.1177/2472555217752140.

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We describe the main characteristics of the Novartis Helios data analysis software system (Novartis, Basel, Switzerland) for plate-based screening and profiling assays, which was designed and built about 11 years ago. It has been in productive use for more than 10 years and is one of the important standard software applications running for a large user community at all Novartis Institutes for BioMedical Research sites globally. A high degree of automation is reached by embedding the data analysis capabilities into a software ecosystem that deals with the management of samples, plates, and resu
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Walsh, Emily, and Ilseung Cho. "Using Evernote as an Electronic Lab Notebook in a Translational Science Laboratory." Journal of Laboratory Automation 18, no. 3 (2012): 229–34. http://dx.doi.org/10.1177/2211068212471834.

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Figueiredo, Ludmilla, Cédric Scherer, and Juliano Sarmento Cabral. "A simple kit to use computational notebooks for more openness, reproducibility, and productivity in research." PLOS Computational Biology 18, no. 9 (2022): e1010356. http://dx.doi.org/10.1371/journal.pcbi.1010356.

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The ubiquitous use of computational work for data generation, processing, and modeling increased the importance of digital documentation in improving research quality and impact. Computational notebooks are files that contain descriptive text, as well as code and its outputs, in a single, dynamic, and visually appealing file that is easier to understand by nonspecialists. Traditionally used by data scientists when producing reports and informing decision-making, the use of this tool in research publication is not common, despite its potential to increase research impact and quality. For a sing
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Olson, Heidi, Greg Matthias, and Kevin Mason. "The Biology of Evaluating Skin-Care Products." American Biology Teacher 83, no. 8 (2021): 532–36. http://dx.doi.org/10.1525/abt.2021.83.8.532.

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The goal of this inquiry activity is to evaluate a variety of skin-care products on simulated skin cells using Orbeez, a brand of superabsorbent polymers. These small beads can quickly absorb water but will dry out in the air, thus perfectly representing our own skin cells. This property makes Orbeez an acceptable model for human skin, and test material for evaluating various skin-care products. Students will observe the quantitative changes that happened to the mass of the samples to determine the percent change. They will also observe the qualitative changes that happened throughout the lab
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Ludtke, Steven J., Laurie Nason, Haili Tu, Liwei Peng, and Wah Chiu. "Object Oriented Database and Electronic Notebook for Transmission Electron Microscopy." Microscopy and Microanalysis 9, no. 6 (2003): 556–65. http://dx.doi.org/10.1017/s1431927603030575.

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As high-resolution biological transmission electron microscopy (TEM) has increased in popularity over recent years, the volume of data and number of projects underway has risen dramatically. A robust tool for effective data management is essential to efficiently process large data sets and extract maximum information from the available data. We present the Electron Microscopy Electronic Notebook (EMEN), a portable, object-oriented, web-based tool for TEM data archival and project management. EMEN has several unique features. First, the database is logically organized and annotated so multiple
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Strasser, C. A., and S. E. Hampton. "The fractured lab notebook: undergraduates and ecological data management training in the United States." Ecosphere 3, no. 12 (2012): art116. http://dx.doi.org/10.1890/es12-00139.1.

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Babaian, Caryn. "Time Travel and the Naturalist's Notebook: Vladimir Nabokov Meets the TimeTree of Life." American Biology Teacher 80, no. 9 (2018): 650–58. http://dx.doi.org/10.1525/abt.2018.80.9.650.

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Combining the TimeTree of Life database with the skill set of a naturalist, transitional changes, speciation, and evolutionary concepts emerge as a process in which students create and are fully engaged in a narrative & theme-based lesson plan/lab that merges with a scientific drawing experience that shadows the life of the naturalist and author Vladimir Nabokov. The interdisciplinary story and science of Nabokov offer a glimpse into applied arts as an exploratory scientific practice that encourages creativity and evolutionary thinking.
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Tsalaportas, Panagiotis G., Vasileios M. Kapinas, and George K. Karagiannidis. "Solar Lab Notebook (SLN): An Ultra-Portable Web-Based System for Heliophysics and High-Security Labs." IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing 8, no. 8 (2015): 4141–50. http://dx.doi.org/10.1109/jstars.2015.2444332.

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Feldhoff, Kim, Tim Opatz, Hajo Wiemer, Martin Zinner, and Steffen Ihlenfeldt. "Benchmarking and Lessons Learned from Using SharePoint as an Electronic Lab Notebook in Engineering Joint Research Projects." Data 10, no. 7 (2025): 92. https://doi.org/10.3390/data10070092.

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The adoption of Electronic Lab Notebooks (ELNs) significantly enhances research operations by enabling the streamlined capture, storage, and dissemination of data. This promotes collaboration and ensures organised and efficient access to critical research information. Microsoft SharePoint® (SP) is an established, widely used, web-based platform with advanced collaboration capabilities. This study investigates whether SP can meet the needs of engineering research projects, particularly in a collaborative environment. The paper outlines the process of adapting SP into an ELN tool and evaluates i
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Doody, Sara, and Natasha Artemeva. "“Everything Is in the Lab Book”: Multimodal Writing, Activity, and Genre Analysis of Symbolic Mediation in Medical Physics." Written Communication 39, no. 1 (2021): 3–43. http://dx.doi.org/10.1177/07410883211051634.

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Writing and genre scholarship has become increasingly attuned to how various nontextual features of written genres contribute to the kinds of social actions that the genres perform and to the activities that they mediate. Even though scholars have proposed different ways to account for nontextual features of genres, such attempts often remain undertheorized. By bringing together Writing, Activity, and Genre Research, and Multimodal Interaction Analysis, the authors propose a conceptual framework for multimodal activity-based analysis of genres, or Multimodal Writing, Activity, and Genre (MWAG)
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Akram, G., and Y. Jasmy. "Lab VIEW-based Planar Multilayered Model for Estimation of the Absorbed Energy Inside Biological Tissues [EM Programmer's Notebook]." IEEE Antennas and Propagation Magazine 50, no. 2 (2008): 152–58. http://dx.doi.org/10.1109/map.2008.4562280.

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Schmieg, Barbara, Nico Brandt, Vera J. Schnepp, et al. "Structured Data Storage for Data-Driven Process Optimisation in Bioprinting." Applied Sciences 12, no. 15 (2022): 7728. http://dx.doi.org/10.3390/app12157728.

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Bioprinting is a method to fabricate 3D models that mimic tissue. Future fields of application might be in pharmaceutical or medical context. As the number of applicants might vary between only one patient to manufacturing tissue for high-throughput drug screening, designing a process will necessitate a high degree of flexibility, robustness, as well as comprehensive monitoring. To enable quality by design process optimisation for future application, establishing systematic data storage routines suitable for automated analytical tools is highly desirable as a first step. This manuscript introd
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Ghiandoni, Gian Marco, Michael J. Bodkin, Beining Chen, et al. "Development and Application of a Data-Driven Reaction Classification Model: Comparison of an Electronic Lab Notebook and Medicinal Chemistry Literature." Journal of Chemical Information and Modeling 59, no. 10 (2019): 4167–87. http://dx.doi.org/10.1021/acs.jcim.9b00537.

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Lundy, Philip Alan, and Nicholas W. Lukacs. "CSI Ann Arbor: A Middle School WebQuest Look at PCR Technology (34.2)." Journal of Immunology 178, no. 1_Supplement (2007): S1. http://dx.doi.org/10.4049/jimmunol.178.supp.34.2.

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Abstract A WebQuest is a journey of understanding using information found on the Internet. Students are placed in a situation and guided through their quest, finishing with an individual or group project. At the Middle School level students are being introduced to the concepts of genetics and DNA. This curriculum is designed as an extension to a student’s understanding of DNA and an introduction to the polymerase chain reaction (PCR), an essential technology used in immunological research. Every piece of DNA contains areas called introns that seem to provide no genetic information. In 1984, Dr
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Geneve, Robert L. "Using Interactive Multimedia to Enhance Student Access to Information on Plant Anatomy and Cell Biology." HortScience 32, no. 3 (1997): 432B—432. http://dx.doi.org/10.21273/hortsci.32.3.432b.

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An interactive multimedia presentation was developed using authoring software (Authorware from Macromedia) to provide information on plant anatomy and cell biology. Our current course in growth and development of horticultural crops has limited time and lab facilities available for these subjects, yet a good foundation in this area is important to understanding growth and development. This software uses a variety of techniques, including color digital images, illustrations, cartoon animation, and video, to teach aspects of cell biology and different plant cell types. In addition, a review sess
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Smith, Chase, Matthew Todd, Luc Patiny, et al. "SCINDR - The SCience INtroDuction Robot that will Connect Open Scientists." Research Ideas and Outcomes 2 (July 27, 2016): e9995. https://doi.org/10.3897/rio.2.e9995.

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This project will develop a way to connect, in real time, globally disparate researchers who are doing similar science so that they can work better and faster towards the development of new medicines. The scientific literature already fulfills the role of notifying researchers about work that has been done, and social media has recently evolved to alert researchers to what is being done. While these new communication technologies simplify the collaborative process between widely distributed researchers, there still exists a major gap in efficient real time alerting and updating. We aim to auto
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Hemani, Yousuf, Kilian Koch, Oscar Mendo-Diaz, Anusch Bachhofner, Simone Baffelli, and Davide Bleiner. "The openBIS Digital Platform for Instrumentation and Data Workflow in the Analytical Laboratory." CHIMIA 79, no. 1-2 (2025): 36–45. https://doi.org/10.2533/chimia.2025.36.

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The management of scientific data plays a key role in all research areas and has increased in importance. Providing researchers with customizable data management tools is crucial for effectively managing data according to the FAIR principles. These principles have been defined by Wilkinson et al. in 2016, which describe how scientific data should be managed.[1] To support the specific needs of researchers at Empa, openBIS[2] was chosen as a FAIR compliant data management platform. OpenBIS is an Electronic Laboratory Notebook (ELN) and Laboratory Information Management System (LIMS) developed a
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Holtgrewe, Manuel, Oliver Stolpe, Mikko Nieminen, et al. "VarFish: comprehensive DNA variant analysis for diagnostics and research." Nucleic Acids Research 48, W1 (2020): W162—W169. http://dx.doi.org/10.1093/nar/gkaa241.

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Abstract VarFish is a user-friendly web application for the quality control, filtering, prioritization, analysis, and user-based annotation of DNA variant data with a focus on rare disease genetics. It is capable of processing variant call files with single or multiple samples. The variants are automatically annotated with population frequencies, molecular impact, and presence in databases such as ClinVar. Further, it provides support for pathogenicity scores including CADD, MutationTaster, and phenotypic similarity scores. Users can filter variants based on these annotations and presumed inhe
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Chatterjea, Devavani, and Grace Linder. "Building a toolkit: An undergraduate teaching laboratory sequence in immunology (50.1)." Journal of Immunology 188, no. 1_Supplement (2012): 50.1. http://dx.doi.org/10.4049/jimmunol.188.supp.50.1.

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Abstract We have designed a laboratory curriculum in immunology where students build and use a toolkit of basic techniques. In the first 10 weeks, students learn how to isolate human and mouse immune cells, label cells with antibodies, perform magnetic enrichment, flow cytometry analysis, T cell proliferation, and ELISA assays. We emphasize keen observation, excellent record keeping, and protocol development. We ensure that each team has at least two opportunities to perform each new technique. Students survey the published literature and formulate a novel question about effects of a dietary s
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Sanei, Arghavan, and Jinghui Cheng. "Characterizing Usability Issue Discussions in Open Source Software Projects." Proceedings of the ACM on Human-Computer Interaction 8, CSCW1 (2024): 1–26. http://dx.doi.org/10.1145/3637307.

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Usability is a crucial factor but one of the most neglected concerns in open source software (OSS). While far from an ideal approach, a common practice that OSS communities adopt to collaboratively address usability is through discussions on issue tracking systems (ITSs). However, there is little knowledge about the extent to which OSS community members engage in usability issue discussions, the aspects of usability they frequently target, and the characteristics of their collaboration around usability issue discussions. This knowledge is important for providing practical recommendations and r
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Yeole, Gaurav, Saniya Sahdev, Matthew Collins, et al. "A Pipeline for Processing Specimen Images in iDigBio - Applying and Generalizing an Examination of Mercury Use in Preparing Herbarium Specimens." Biodiversity Information Science and Standards 1 (August 15, 2017): e20326. https://doi.org/10.3897/tdwgproceedings.1.20326.

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iDigBio currently references over 22 million media files, and stores approximately 120 terabytes worth of those media files co-located with our computing infrastructure (Matsunaga et al. 2013). Using these images for scientific research is a logistical and technical challenge. Transferring large numbers of images requires programming skill, bandwidth, and storage space. While simple image transformations such as resizing and generating histograms are approachable on desktops and laptops, the neural networks commonly used for learning from images require server-based graphical processing units
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Koschate, Miriam, Elahe Naserian, Luke Dickens, Avelie Stuart, Alessandra Russo, and Mark Levine. "ASIA: Automated Social Identity Assessment using linguistic style." Behavior Research Methods 53, no. 4 (2021): 1762–81. http://dx.doi.org/10.3758/s13428-020-01511-3.

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AbstractThe various group and category memberships that we hold are at the heart of who we are. They have been shown to affect our thoughts, emotions, behavior, and social relations in a variety of social contexts, and have more recently been linked to our mental and physical well-being. Questions remain, however, over the dynamics between different group memberships and the ways in which we cognitively and emotionally acquire these. In particular, current assessment methods are missing that can be applied to naturally occurring data, such as online interactions, to better understand the dynam
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Breddels, Maarten A., and Jovan Veljanoski. "Vaex: big data exploration in the era of Gaia." Astronomy & Astrophysics 618 (October 2018): A13. http://dx.doi.org/10.1051/0004-6361/201732493.

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We present a new Python library, called vaex, intended to handle extremely large tabular datasets such as astronomical catalogues like the Gaia catalogue, N-body simulations, or other datasets which can be structured in rows and columns. Fast computations of statistics on regular N-dimensional grids allows analysis and visualization in the order of a billion rows per second, for a high-end desktop computer. We use streaming algorithms, memory mapped files, and a zero memory copy policy to allow exploration of datasets larger than memory, for example out-of-core algorithms. Vaex allows arbitrar
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"E-Lab Notebook." Chemical & Engineering News Archive 79, no. 14 (2001): obc. http://dx.doi.org/10.1021/cen-v079n014.obc.

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"E-Lab Notebook." Chemical & Engineering News 79, no. 44 (2001): obc. http://dx.doi.org/10.1021/cen-v079n044.obc.

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Foster, Erin D., Elizabeth C. Whipple, and Gabriel R. Rios. "Implementing an institution-wide electronic lab notebook initiative." Journal of the Medical Library Association 110, no. 2 (2022). http://dx.doi.org/10.5195/jmla.2022.1407.

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Background: To strengthen institutional research data management practices, the Indiana University School of Medicine (IUSM) licensed an electronic lab notebook (ELN) to improve the organization, security, and shareability of information and data generated by the school’s researchers. The Ruth Lilly Medical Library led implementation on behalf of the IUSM’s Office of Research Affairs. Case Presentation: This article describes the pilot and full-scale implementation of an ELN at IUSM. The initial pilot of the ELN in late 2018 involved fifteen research labs with access expanded in 2019 to all ac
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Foster, Erin D., Elizabeth C. Whipple, and Gabriel R. Rios. "Implementing an institution-wide electronic lab notebook initiative." Journal of the Medical Library Association 110, no. 2 (2022). http://dx.doi.org/10.5195/jmla.2022.1407.

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Background: To strengthen institutional research data management practices, the Indiana University School of Medicine (IUSM) licensed an electronic lab notebook (ELN) to improve the organization, security, and shareability of information and data generated by the school’s researchers. The Ruth Lilly Medical Library led implementation on behalf of the IUSM’s Office of Research Affairs. Case Presentation: This article describes the pilot and full-scale implementation of an ELN at IUSM. The initial pilot of the ELN in late 2018 involved fifteen research labs with access expanded in 2019 to all ac
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Johnson, Staci N. "Why Do I Need a Lab Notebook? Teaching Responsible Conduct of Research with CURE Lab Notebooks." CourseSource 10 (2023). http://dx.doi.org/10.24918/cs.2023.31.

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Pain, Elisabeth. "How to keep a lab notebook." Science, September 3, 2019. http://dx.doi.org/10.1126/science.caredit.aaz3678.

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Harding, Rachel, Mani Ravichandran, Cheryl Arrowsmith, and Aled Edwards. "HMGB1 expression and purification - 27th November 2017." November 27, 2017. https://doi.org/10.5281/zenodo.1116432.

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Zulauf, Bert, and Nina Knipprath. "Electronic Lab Notebooks - early research practice in teaching." November 13, 2019. https://doi.org/10.5281/zenodo.4787258.

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Anyone who has his academic background in a natural science subject is already familiar with it: the lab notebook. Even in times of digitization, the most common type of laboratory documentation can still be found on paper. But what happens to these books when they are full? When the researcher changes the workgroup? Or if there simply is no longer a contact person for this lab notebook? Deciphering handwriting is not always the easiest task for man and machine, much of the collected knowledge is lost, many experiments are made over and over again instead of focusing on innovation. All this ca
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Ball, Philip. "Computer gleans chemical insight from lab notebook failures." Nature, May 4, 2016. http://dx.doi.org/10.1038/nature.2016.19866.

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Shu-Yu, Chen, P. Feilen Lukas, Chávez-Gutiérrez Lucía, Steiner Harald та Zacharias Martin. "Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site". 20 травня 2023. https://doi.org/10.5281/zenodo.8000297.

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Raw data, initial PDB files, and Python&nbsp;codes used to generate the figures in the work &quot;&nbsp;<strong>Enzyme-substrate hybrid &beta;-sheet controls geometry and water access to the &gamma;-secretase active site &quot;&nbsp;</strong>in Communication Biology. To generate the figures, extract the data by &quot;tar -xzvf data.tar.gz&quot; and&nbsp;launch Jupyter notebook/lab in the directory &quot;./data/analysis&quot; and run all codes in&nbsp;notebooks &quot;Plot_restraint-free.ipynb&quot; and &quot;Plot_PMF.ipynb&quot;.&nbsp; All data were analyzed using cpptraj, pytraj, and MMPBSA.py
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Williams, E. P., and A. N. Bullock. "Purification of ACVR2, TGFBR1, TGFBR2 and BMPR2 for pull down with XIAP." June 12, 2018. https://doi.org/10.5281/zenodo.1287852.

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Williams, E. P., and A. N. Bullock. "Thermal melt analysis of compound binding." June 12, 2018. https://doi.org/10.5281/zenodo.1287854.

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50

"Turn on the Power of Our Electronic Lab Notebook." Chemical & Engineering News 88, no. 21 (2010): 17. http://dx.doi.org/10.1021/cen-v088n021.p017.

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