Dissertations / Theses on the topic 'Laboratory information management system (LIMS)'
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Ademuyiwa, Toluwaleke. "Development of Open source Laboratory Information Management System (LIMS) For Human Biobanking." University of the Western Cape, 2018. http://hdl.handle.net/11394/6326.
Full textBiobanks are collections of biological samples and associated data for future use. The day to day activities in a biobank laboratory is underpinned by a laboratory information management system (LIMS). For example, the LIMS manages the execution of tests on biospecimens and track their movement and processing through the laboratory. There are a range of commercially available Biobank LIMS systems on the market but their costs are prohibitive in a resource limited setting. The cost of Commercial off-the-shelf software includes the initial cost of acquiring the system, as well as the cost of maintenance and support throughout the software's life cycle. The Bika LIMS system on the other hand is Free and open source software (FOSS) with decreased license cost, used routinely in non-medical laboratories. Ideally, if Bika LIMS could be customised to handle human biospecimens, then both biobanks and genetics laboratories could benefit. Central to any biobank functionality in Bika LIMS is the ability to import information from routine biomedical equipment. We identified two instruments that are key to human biobanking and are lacking in Bika LIMS namely BioDrop ?LITE and the Qubit Fluorometric instrument. Import interfaces for importing DNA/RNA concentration analyses from these instruments and management of the results with associated sample information would add value to the LIMS. The aim of the thesis was to customise Bika LIMS for utility in a biomedical laboratory. In collaboration with colleagues at Tygerberg medical school, the Bika LIMS software was customised to accommodate the DNA and RNA concentration analyses results for a pathology laboratory and the LIMS workflows customised for use at Tygerberg medical school. In this process the manual operations of Tygerberg medical school laboratory would migrate to the use of Bika LIMS. The analytical module in Bika LIMS was implemented using PYTHON, by using logic that allows importing of specific analyses. A template was created for the BioDrop ?LITE and Qubit Fluorometric instruments used for developing the interface for an analysis import form. The instruments generate results in CSV file format. A parser was created to read and parse the files uploaded from the import form, by splitting them into parts, extracting the data, and populating key-value pairs. The controller manages the submission of the form by initialising the parser that imports the specific file into the LIMS where it is managed by the configured Bika LIMS workflow.
Baldaniya, Hitesh D. "Laboratory information management system study & development of LIMS web platform application for CTCV - Coimbra." Master's thesis, Escola Superior de Tecnologia e Gestão de Oliveira do Hospital, 2018. http://hdl.handle.net/10400.26/31639.
Full textN/A
Bendou, Hocine. "Baobab LIMS: An open source biobank laboratory information management system for resource-limited settings." University of the Western Cape, 2019. http://hdl.handle.net/11394/6773.
Full textA laboratory information management system (LIMS) is central to the informatics infrastructure that underlies biobanking activities. To date, a wide range of commercial and open source LIMS are available. The decision to opt for one LIMS over another is often influenced by the needs of the biobank clients and researchers, as well as available financial resources. However, to find a LIMS that incorporates all possible requirements of a biobank may often be a complicated endeavour. The need to implement biobank standard operation procedures as well as stimulate the use of standards for biobank data representation motivated the development of Baobab LIMS, an open source LIMS for Biobanking. Baobab LIMS comprises modules for biospecimen kit assembly, shipping of biospecimen kits, storage management, analysis requests, reporting, and invoicing. Baobab LIMS is based on the Plone web-content management framework, a server-client-based system, whereby the end user is able to access the system securely through the internet on a standard web browser, thereby eliminating the need for standalone installations on all machines. The Baobab LIMS components were tested and evaluated in three human biobanks. The testing of the LIMS modules aided in the mapping of the biobanks requirements to the LIMS functionalities, and furthermore, it helped to reveal new user suggestions, such as the enhancement of the online documentation. The user suggestions are demonstrated to be important for both LIMS strengthen and biobank sustainability. Ultimately, the practical LIMS evaluations showed the ability of Boabab LIMS to be used in the management of human biobanks operations of relatively different biobanking workflows.
Voegele, Catherine. "Development of an integrated Information Technology System for management of laboratory data and next-generation sequencing workflows within a cancer genomics research platform." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10095/document.
Full textThe aim of my thesis work was to develop bioinformatics tools to improve the traditional scientific information management within a large research centre and especially within a genomics platform. Three tools have been developed: an electronic laboratory notebook, a laboratory information management system for genomics applications including next generation sequencing, as well as a sample management system for large biobanks. This work has been conducted in close collaboration with biologists, epidemiologists and IT specialists. It has also included the setup of interactions between the different tools to make an integrated IT system. The three tools have been rapidly adopted by all the scientists of the research centre and are now daily used for the tracking of all the laboratory’s activities but also more globally for the research centre’s other scientific activities. These tools are transposable in other research institutes
Mendes, João Zeferino Duarte. "Upgrade de interface web de sistema de gestão de Informação laboratorial (LIMS) : gestão de relacionamento com cliente, capital humano e conhecimento." Master's thesis, Instituto Superior de Economia e Gestão, 2014. http://hdl.handle.net/10400.5/10138.
Full textO presente projeto de tese tem como objetivo descrever e partilhar o projeto de upgrade da interface web de um Sistema de Gestão de Informação Laboratorial (LIMS) no âmbito da estratégia de Marketing implementada pela Sucursal em Portugal de um Laboratório Químico Ambiental, assim como a consequente Gestão de relacionamento com o Cliente, Gestão de Capital Humano e Conhecimento na utilização da mesma. Este trabalho teve por base um enquadramento teórico do setor de atividade e respetivo produto, assim como também da Gestão de relacionamento com o Cliente, Gestão de Capital Humano e Conhecimento. A descrição do projeto propriamente dito surge de seguida, desde a sua versão inicial até à versão final atual ainda existente, incluindo a descrição da implementação e operacionalização do respetivo upgrade. A nível de metodologia, foi efetuada uma revisão bibliográfica sobre o upgrade de um produto existente assim como sistemas LIMS, de forma a fundamentar os passos seguidos no projeto. Foi também consultada informação interna do Laboratório Químico Ambiental e revisitada a experiência vivida pelo autor deste trabalho durante o período de implementação e operacionalização deste projeto na Sucursal em Portugal. Tendo como foco os clientes existentes, tornou-se num produto crítico para a simplificação da gestão da informação no contacto entre o cliente e o Laboratório Químico Ambiental assim como para a sua fidelização, sendo também uma importante ferramenta de Marketing junto de potenciais clientes por diferenciação dos concorrentes.
This thesis project aims to describe and share the upgrade of a Laboratory Management Information System (LIMS) web interface, under the Marketing strategy implemented by the Portuguese office of an Environmental Chemistry Laboratory, as well corresponding Customer Relationship, Human Capital and Knowledge Management in loyalty using this same system. This work was based on a theoretical framework of the respective activity sector and product, followed as well by Customer Relationship, Human Capital and Knowledge Management. The description of the project arises then, since its initial release until the current final version that in fact still exists, including the description of the corresponding upgrade implementation and operation tasks. In terms of methodology, a literature review on the upgrade of an existing product and LIMS systems was carried out to support the steps of the project. Query internal information of the Environmental Chemistry Laboratory and this project author lived revisited experience during the period of implementation and operation in Portuguese branch was consulted as well. Focusing on existing Customers, this upgrade of the LIMS web interface became a critical product for information management simplifying during the contact between Customer and the Environmental Chemistry Laboratory provider as well as for their loyalty, and at the same time also treated as an important marketing tool near Prospects as differentiation from competitors.
Katungire, Tsitsi. "An exploratory study of factors affecting the availability of laboratory consumables at state-owned medical laboratories in Harare Province, Zimbabwe." University of the Western Cape, 2011. http://hdl.handle.net/11394/5367.
Full textThe Zimbabwean government recognizes the critical role laboratories play in ensuring the health of the nation. Well-resourced and functioning laboratories are the sine qua non of effective diagnosis, treatment and clinical monitoring of medical problems such as HIV/AIDS, tuberculosis and malaria. In Zimbabwe, frequent unavailability of essential laboratory reagents and consumables have been reported but less well-reported are the factors associated with these "stockouts" at medical laboratories. Applying qualitative research methodologies, this study sought to explore the bottlenecks to the availability of laboratory consumables at state-owned medical laboratories in Harare Province. Semi-structured interviews were used to elicit stakeholders' perspectives and experiences with regard to the availability of laboratory consumables. These were complemented by observation of procurement, supply and distribution processes and individual follow-up interviews in 7 facilities where medical laboratory scientists were purposively selected. Rigour was ensured through data-source triangulation, provision of thick descriptions of the setting, maintaining an audit trail and transcribing data verbatim. Data analysis identified recurring themes and key suggestions made by respondents. A complex web of economic, human resources and supply chain factors affect laboratory commodity availability in Harare. Salient factors negatively affecting commodity availability included inadequate funding, human resources, poor communication and coordination among stakeholders, lack of transport, long lead times and limited inventory management skills. A comprehensive approach to resolving the challenge is warranted through advocating for more funding, complementing donor efforts on staff retention, improved coordination and collaboration among stakeholders and re-designing the laboratory supply chain. Further research would assist in determining ways of efficiently utilizing the limited available resources.
Hedlund, Niclas. "Tyst kunskap och produktdatasystem vid medicinteknisk tillverkning : Pilotstudie av system för produktdatahantering och kartläggning av den tysta kunskapen vid Nationellt respirationscetrum, NRC." Thesis, Uppsala University, Department of Information Technology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-126753.
Full textThis thesis looks at two sides of the same coin: how to support the production and future development at a specialist medical technology department at Danderyd Hospital. The two sides are; a pilot study of a product management system (PDM) and an interview based study on the characteristics of the silent knowledge of the technicians. The department (National respiratory centre, NRC) is facing retirement of several key employees.
The technical study shows that the success of an implementation is largely dependent on the users’ prior knowledge and use of a 3D Computer aided design system (CAD).The system itself is shown to fulfill the Lifecycle requirement of tracking the products (mostly tracheostomy tubes) but without a CAD centered workflow, some substantial education and preferably some new recruits, an implementation of the PDM system will fail. The author recommends development of the current “low-tech” system of MS Excel and Access rather than redistribute the dependency from technician towards a complex, commercial software and its vendor.
The analysis of the technicians’ silent knowledge with the newly developed method, epithet for silent knowledge (ETK), shows that the longer employment time:
- the more differentiated technicians become in describing their work,
- practical knowledge are regarded higher and
- the social and collective problem solving factors of the work becomes more important.
Typically, it is shown that a new employee should preferably enjoy problem solving, being pragmatic and social as well as having some prior education or work experience in a CAD and/or a PDM system.
Zhu, Jianyong. "Automating Laboratory Operations by Intergrating Laboratory Information Management Systems (LIMS) with Analytical Instruments and Scientific Data Management System (SDMS)." Thesis, 2005. http://hdl.handle.net/1805/323.
Full textThe large volume of data generated by commercial and research laboratories, along with requirements mandated by regulatory agencies, have forced companies to use laboratory information management systems (LIMS) to improve efficiencies in tracking, managing samples, and precisely reporting test results. However, most general purpose LIMS do not provide an interface to automatically collect data from analytical instruments to store in a database. A scientific data management system (SDMS) provides a “Print-to-Database” technology, which facilitates the entry of reports generated by instruments directly into the SDMS database as Windows enhanced metafiles thus to minimize data entry errors. Unfortunately, SDMS does not allow performing further analysis. Many LIMS vendors provide plug-ins for single instrument but none of them provides a general purpose interface to extract the data from SDMS and store in LIMS. In this project, a general purpose middle layer named LabTechie is designed, built and tested for seamless integration between instruments, SDMS and LIMS. This project was conducted at American Institute of Technology (AIT) Laboratories, an analytical laboratory that specializes in trace chemical measurement of biological fluids. Data is generated from 20 analytical instruments, including gas chromatography/mass spectrometer (GC/MS), high performance liquid chromatography (HPLC), and liquid chromatography/mass spectrometer (LC/MS), and currently stored in NuGenesis SDMS iv (Waters, Milford, MA). This approach can be easily expanded to include additional instruments.
Lerch, Spencer. "Academic laboratory information management system: a tool for science and computer science students." Thesis, 2011. http://hdl.handle.net/1805/2607.
Full textProof of Concept - An Academic LIMS application: The aim of this project is the creation of an open-source, freeware LIMS application that can be used in an academic setting as a teaching tool for both chemistry and computer science students. The LIMS package will combine an application, developed using VB.NET, to manage the data with other open-source or freeware programs such as MySQL and WEKA. The numerous commercial chemical informatics applications available are useful tools to learn how to manage data from a user's standpoint. However, they are not readily available to the average student, nor do they offer a great understanding into how they were developed from a programmer's frame of mind. There is a great void here that, if filled can greatly help the academic community.
Witty, Derick. "Implementation of a Laboratory Information Management System To Manage Genomic Samples." Thesis, 2013. http://hdl.handle.net/1805/3521.
Full textA Laboratory Information Management Systems (LIMS) is designed to manage laboratory processes and data. It has the ability to extend the core functionality of the LIMS through configuration tools and add-on modules to support the implementation of complex laboratory workflows. The purpose of this project is to demonstrate how laboratory data and processes from a complex workflow can be implemented using a LIMS. Genomic samples have become an important part of the drug development process due to advances in molecular testing technology. This technology evaluates genomic material for disease markers and provides efficient, cost-effective, and accurate results for a growing number of clinical indications. The preparation of the genomic samples for evaluation requires a complex laboratory process called the precision aliquotting workflow. The precision aliquotting workflow processes genomic samples into precisely created aliquots for analysis. The workflow is defined by a set of aliquotting scheme attributes that are executed based on scheme specific rules logic. The aliquotting scheme defines the attributes of each aliquot based on the achieved sample recovery of the genomic sample. The scheme rules logic executes the creation of the aliquots based on the scheme definitions. LabWare LIMS is a Windows® based open architecture system that manages laboratory data and workflow processes. A LabWare LIMS model was developed to implement the precision aliquotting workflow using a combination of core functionality and configured code.
Lai, Shih-Chieh, and 賴仕杰. "Reagents and Consumables Management and Demand Forecasting Information System of Medical Laboratory." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/93951191435265548978.
Full text朝陽科技大學
資訊管理系碩士班
100
The purpose of medical examination is to help people finding the possible causes of diseases and then to assist doctors making judgment for cure. Thus medical examination is a crucial step among medical behaviors. To guarantee the quality of examination, inventory management of reagents and consumables is also a requiring groundwork, besides keeping the proper function of examining works. However, it is a big test for the staff to effectively manage reagents of various categories and complex packages. So far, the medical laboratory we cooperated in this study still has their materials purchased and managed by manpower, which is a method of time-consuming, labor-consuming and mistakable, and the instantaneous control of inventory is also impossible and therefore results in complicated management labor waste. Aiming at these problems, we designed an online management information system of reagents and consumables, replacing human labor with computers to do the complicated works of ordering, examining, importation, and exportation and checking of materials, and also through the managing of the bar-code system with bar-code reader and bar-code printer. The importations and exportations of reagents and consumables can be easily recorded and saved by utilizing bar-code. This will minimize the time of paper work, preventing the problems caused by human labor from happening. The system also provide alerts and warnings to reduce errors. complications. Furthermore, the demands of reagents and consumables vary with factors such seasons, geographic locations, different hospital groups and so on. Therefore, another task of this study is to assist purchasers to precisely forecast the consumptions. The laboratory we cooperated has no any forecasting system and purchasing is totally based on personal experience of purchasers. When newcomer is in charge of purchasing, the exceeding purchasing results in hoard and overdue reagents or the omission of the fluctuating usage of specific reagents results in deficiency and standstill of the work which are commonly situations appeared. Thus we developed a demand forecasting system for reagents and consumables, based on historical data of reagent order and consumption, combing the forecasting model developed by scholars Liao Yueh Hsiang et al. to calculate the demand of each reagent.
Woo, Yu-Te, and 胡裕德. "Planning and Implementation of the Management Information System for a Testing Laboratory." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/71262906574794785991.
Full text大同大學
資訊工程學系(所)
103
In recent years, production and manufacturing businesses are no longer dominant the market. Enterprises with service type business are also expanding rapidly. One example is the electromagnetic compatibility test service for consumer products. Regulation requires that all the consumer products need to pass the electromagnetic compatibility test before they can be send to the market. This results the establishment of the compatibility testing companies. The primary task of the testing laboratory is to perform the compatibility test. Therefore, a good supporting management information system is crucial if we want the engineers focusing mainly on performing the test. The requirements of the client are collected by the sales representatives and all the requirements as well as other supplement information are entered into the information system. The engineers retrieve the working lists from the information system and filled the testing results back to the system. In the mean time, the managers can monitor the status of all the processes. Our job is to work with the testing company to integrate their original management information system and add new functionalities to build a more comprehensive information system. A backup mechanism and backup system are also developed and installed to improve the system availability.
Wang, Yi-hui, and 王義輝. "Design and Implementation of Laboratory Information Management System: Take an Example for Environmental Protection Bureau Kaohsiung County Government." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/67108549645432970450.
Full text嘉南藥理科技大學
環境工程與科學系碩士班
95
Environmental testing belongs to basic engineering in the environment protection system. The essence of environmental testing is problem-based. It can handle the serious environmental problems, including enforcing and redacting the policy of environmental protection. (e.g. establishment of the Environmental Law, environment quality monitoring, environment impact assessment, censorship of the Environment Law, environment improve assessment, and identification of Public nuisance disputes, etc.) These all depend on objective, exactness and justice of environmental testing. At presently, Environmental Protection Administration (EPA) stipulates that the function of environmental testing is to manage public or private testing organization, supervise the environmental analysis departments of various local county and city governments, establish the testing methods for environmental testing technique and standard, check on data quality for EPA’s commissioned project, support EPA’s case or Environmental Law, and analyze trace toxic material, etc. Therefore, all government organizations have Technique Support Sections or Laboratory Offices to analyze air, water, waste, toxic material and soil information, which play an important role in the environmental analysis departments. Because all the testing works be done in the laboratories, we can by Laboratory Information Management System (LIMS) to avoid mistakes, simplify environmental testing work, and practice quality control systems. The LIMS use computer to dispose of diffusion data. It not only can raise the accuracy of the date but also the laboratory’s quality assurance/quality control (QA/QC) program, shorten work time and reduce personnel expense to increased testing efficiency so that the testing data possess justice force.
Meng-Hsin, Lee, and 李孟信. "Development of a Laboratory Information Management System for Integrating of Diagnosis Proteomics and Patient Clinical Data in Hepatocellular carcinoma." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/92666817363680109349.
Full text臺北醫學大學
醫學資訊研究所
92
Hepatocellular carcinoma (HCC or hepatoma) is the leading (20%) and the second (19%) cause for the mortality of male and female HCC population in Taiwan. There are increasing interests for researchers to identify novel biomarkers for HCC for the early detection and the developments of efficient therapy. An integrated-application system for the analysis of HCC data which features convenient storage and retrieving, and capable of analyzing complex information including clinical data, two-dimensional protein gel images, and specific protein was established in the study. This research take advantage of dynamic page, web Servers and database management system, developing a web-based laboratory information management system(LIMS) for integrating diagnosis proteomics and patient clinical data in HCC. The system also equipped with a powerful analytical application which can easily query for interesting protein spots and link these data to clinical information. Its web-based system further facilitates data sharing with international experts through internet easily and effectively. The three major functions that our system provide as follows: 1. LIMS (laboratory information management system): this system is equipped for the collection of proteomic data including two-dimensional protein gel images, information for specific protein spots of interesting, annotation of proteomic information, and the integration of patient’s clinical data. 2. Reference area: a web-based software tool was designed to quickly link to relevant data clinical data and protein databases. This is a research-driven approach to application. 3. Query management: a query form in which a user can specify the variety of parameters defined in the database to search the target data. Those query parameters include pathological section information (sample ID, source), Protein information (access number, protein name, molecular weight, pI), patient information (age, gender, cancer stage) clinical data (GOT, GPT, ALP, LDH, TBIL, DBIL), and others such as the parameters of an experiment protocol, date, operators. In conclusion, the system provide integrated data including patient’s pathological section data, patient data, clinical data, proteomic data and experimental protocols to facilitate researchers to investigate disease relationships with proteins. The LIMS also present the data combining proteomic experiment data and clinical data in a biological level, which is more meaningful to the researches.
Cassim, Naseem. "Developing a laboratory based CCMT programme status reporting system in the Ekurhuleni Health District." Diss., 2013. http://hdl.handle.net/10500/13676.
Full textHealth Studies
M.A. (Public Health with specialisation in Medical Informatics)