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1

Strong, W. L. "Lodgepole pine/Labrador tea type communities of western Canada." Canadian Journal of Botany 80, no. 2 (February 1, 2002): 151–65. http://dx.doi.org/10.1139/b01-147.

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Lodgepole pine/Labrador tea (Pinus contorta Dougl. ex Loud. var. latifolia/Ledum groenlandicum Oeder) relevés were classified and characterized based on data from archival sources (n = 428). Eleven forest communities were recognized and were distinguished by the relative dominance of Sphagnum, Cladina and Cladonia, Lycopodium, Vaccinium species, or feathermosses. Picea mariana (Mill.) BSP was the common secondary successional species. Most paired-community comparisons were nonoverlapping in ordination space, although intermingling sometimes occurred along interfaces. Lodgepole pine/Labrador tea stands occurred on upland sites within the boreal–cordilleran ecoclimatic transition zone along the eastern slopes of the Rocky Mountains from southwestern Alberta to the southern Yukon Territory. Nine communities had mesic to subhygric moisture and submesotrophic to mesotrophic nutrient regimes. The exceptions were a Pinus contorta/Ledum groenlandicum/Sphagnum (wetter sites) and a Pinus contorta/Ledum groenlandicum/Cladina mitis (drier sites) community. An inverse correlation occurred between latitudinal location and elevation of occurrence (r = –0.56, P < 0.001, n = 403) with a northward decline of 65 m/100 km. The concept of a "type community" is proposed for formally documenting the composition of plant communities and optimizing the comparability of different types. Eight of the recognized communities fulfilled the proposed criteria for a type community and two were considered provisional types.Key words: vegetation classification, Pinus contorta, Ledum groenlandicum, type community.
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2

Reichardt, P. B., J. P. Bryant, B. J. Anderson, D. Phillips, T. P. Clausen, M. Meyer, and K. Frisby. "Germacrone defends labrador tea from browsing by snowshoe hares." Journal of Chemical Ecology 16, no. 6 (June 1990): 1961–70. http://dx.doi.org/10.1007/bf01020508.

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3

Ben Lagha, Amel, Katy Vaillancourt, Patricia Maquera Huacho, and Daniel Grenier. "Effects of Labrador Tea, Peppermint, and Winter Savory Essential Oils on Fusobacterium nucleatum." Antibiotics 9, no. 11 (November 10, 2020): 794. http://dx.doi.org/10.3390/antibiotics9110794.

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Bad breath or halitosis is an oral condition caused by volatile sulfur compounds (VSC) produced by bacteria found in the dental and tongue biofilms. Fusobacterium nucleatum is a Gram-negative anaerobic bacterium that has been strongly associated with halitosis. In this study, essential oils (EO) from three plants, Labrador tea (Rhododendron groenlandicum [Oeder] Kron & Judd), peppermint (Mentha x piperita L.), and winter savory (Satureja montana L.), were investigated for their effects on growth, biofilm formation and killing, and VSC production by F. nucleatum. Moreover, their biocompatibility with oral keratinocytes was investigated. Using a broth microdilution assay, winter savory EO and to a lesser extent Labrador tea and peppermint EO showed antibacterial activity against F. nucleatum. A treatment of pre-formed biofilms of F. nucleatum with EO also significantly decreased bacterial viability as determined by a luminescence assay monitoring adenosine triphosphate production. The EO were found to permeabilize the bacterial cell membrane, suggesting that it represents the target of the tested EO. The three EO under investigation were able to dose-dependently reduce VSC production by F. nucleatum. Lastly, no significant loss of cell viability was observed when oral keratinocytes were treated with the EO at concentrations effective against F. nucleatum. This study supports the potential of Labrador tea, peppermint, and winter savory EO as promising agents to control halitosis and promote oral health.
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4

Hébert, François, and Nelson Thiffault. "The Biology of Canadian Weeds. 146. Rhododendron groenlandicum (Oeder) Kron and Judd." Canadian Journal of Plant Science 91, no. 4 (July 2011): 725–38. http://dx.doi.org/10.4141/cjps2010-012.

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Hébert, F. and Thiffault, N. 2011. The Biology of Canadian Weeds. 146. Rhododendron groenlandicum (Oeder) Kron and Judd. Can. J. Plant Sci. 91: 725–738. Rhododendron groenlandicum (Oeder) Kron and Judd, bog Labrador tea, is an evergreen shrub from the Ericacae family native to North America. Bog Labrador tea is associated with the later stages of forest successions in black spruce forest stands of the boreal ecosystems with cool climates, but responds aggressively to forest openings where it is already present. In general, bog Labrador tea is associated with nutrient-poor, acidic soils, with drainage ranging from moist to wet. Layering is the main regeneration strategy of the species; evidence suggests that this could be especially true following disturbances that open the forest canopy. Sexual reproduction maintains viability in undisturbed communities through wind or water dispersal. Rhododendron groenlandicum acclimates more rapidly relative to black spruce after perturbations through a higher rate of resource utilization when resources are available. The species is a highly competitive shrub for soil nutrients; it competes with regenerating conifers for soil nitrogen and phosphorus. It can also assimilate organic nitrogen from the soil through its mycorhizae. These characteristics may lead to the formation of ericaceous heaths that can stay unforested indefinitely. However, this species can be eradicated by herbicides (glyphosate) and heavy site scarification can limit its propagation.
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5

Гапоненко, Валентина Петровна, and Ольга Леонидовна Левашова. "Phytochemical study of phenolic compounds of labrador tea (Lédum palústre L.)." ScienceRise 11, no. 4 (16) (November 29, 2015): 14. http://dx.doi.org/10.15587/2313-8416.2015.54483.

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6

McGill, Colin M., Patrick L. Tomco, Regina M. Ondrasik, Kaitlyn C. Belknap, Gaelen K. Dwyer, Daniel J. Quinlan, Thomas A. Kircher, et al. "Therapeutic effect of Northern Labrador tea extracts for acute myeloid leukemia." Phytotherapy Research 32, no. 8 (April 27, 2018): 1636–41. http://dx.doi.org/10.1002/ptr.6091.

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7

Rapinski, Michel, Lina Musallam, John Thor Arnason, Pierre Haddad, and Alain Cuerrier. "Adipogenic Activity of Wild Populations ofRhododendron groenlandicum, a Medicinal Shrub from the James Bay Cree Traditional Pharmacopeia." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/492458.

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The traditional medicinal plant, Labrador tea (Rhododendron groenlandicum(Oeder) Kron & Judd; Ericaceae), present in the pharmacopoeia of the Cree of Eeyou Istchee, has shown glitazone-like activity in the 3T3-L1 adipogenesis bioassay. This activity has been attributed to phenolic compounds, which have been shown to vary in this plant as a function of insolation parameters. The goal of this study was to determine if these changes in phenolic content were pharmacologically significant. Leaves were harvested in 2006 throughout the James Bay region of Northern Quebec and ethanol extracts were testedin vitrousing the 3T3-L1 murine cell line adipogenesis bioassay. This traditional medicinal plant was found active in the assay. However, there was no detectable spatial pattern in the accumulation of intracellular triglycerides, suggesting that such patterns previously observed in the phenolic profile of Labrador tea were not pharmacologically significant. Nonetheless, a reduction in the adipogenic activity was observed and associated with higher concentrations of quercetin for which selected environmental variables did not appropriately explain its variation.
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8

Li, J., D. Percival, J. Hoyle, J. White, K. Head, and K. Pruski. "Phenology and yield of native fruits cloudberry/bakeapple (Rubus chamaemorus L.) and lingonberry/partridgeberry (Vaccinium vitis-idaea L.) grown in Southern Labrador, Canada." Canadian Journal of Plant Science 96, no. 3 (June 1, 2016): 329–38. http://dx.doi.org/10.1139/cjps-2015-0131.

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Plant habitat, growth, fruit yield and occurrence of pollinators in cloudberry and lingonberry fields/bogs were monitored and analyzed at three locations in southern Labrador: Lanse’au Clair (51°41’ N, 57°08’ W), Red Bay (51°43’ N, 56°26’ W), and Cartwright (53°42’ N, 57°0’ W) over the two growing seasons, 2011 and 2012. The length of the growing seasons was 100–120 d ( DFRA 2014 ) with 600–700 growing degree days (GDD) ( AAFC 2014 ). The 2012 season was warmer than 2011. The plants recorded in belt transects belong to six families: Rosaceae, Ericaceae, Pottiaceae, Juncaeae, Equisetaceae, and Sphagnaceae. In the Ericaeae family, Vaccinium vitis-idaea, Arctostaphylos alpina, Empetrum nigrum, and Vaccinium angustifolium were found. In both seasons, the cloudberry was the first to bloom, followed by wild blueberry, lingonberry, and Labrador tea. The fruit yields of cloudberry and partridgeberry in southern Labrador were higher than those recorded in Finland, Norway, and in the USA. Pollinators were present in large numbers. Most of the specimens were from three orders: Hymenoptera, Diptera, and Lepidoptera. Temperature, precipitation, wind, and sunlight affected plant growth and the occurrence of pollinators. To our knowledge this is the most comprehensive study of plant growth, yield, and pollinators’ activity in cloudberry/partridgeberry fields conducted in Southern Labrador, Canada.
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9

Nyade, Praise K., Derek H. C. Wilton, Henry P. Longerich, Gary M. Thompson, and Paul McNeill. "Use of surficial geochemical methods to locate areas of buried uranium mineralization in the Jacque’s Lake area of the Central Mineral Belt, Labrador, Canada." Canadian Journal of Earth Sciences 50, no. 11 (November 2013): 1134–46. http://dx.doi.org/10.1139/cjes-2013-0032.

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Surficial geochemical methods were applied to delineate zones of anomalous uranium and related element concentrations in areas overlain by an extensive blanket of glacial sediments and dense vegetation cover in the Jacque’s Lake area of the Central Mineral Belt, Labrador, Canada. The study involved sampling and analyses of vegetation including black spruce twigs and bark, Labrador tea shoots, and humus. Ash derived from the vegetation samples was analyzed using inductively coupled plasma – mass spectrometry (ICP–MS) following ignition at 450 °C, and humus was analyzed with delayed neutron counting (DNC) for a suite of 35 elements. B-horizon soil was analyzed using aqua regia digestion to investigate potential chemical signatures of bedrock mineralization at the surface. Uranium concentration in humus varied from 0.05 to 885 ppm. Zones exhibiting anomalous U responses were associated with areas proximal to anoxic peat and sphagnum bogs where mobile U species were sequestered. Uranium and pathfinder element (e.g., Pb, V, Sr, and Mo) concentrations were low in the <250 μm fraction of B-horizon soils. The soil geochemistry delineated bedrock U mineralization in areas with <15 cm of overburden and U concentration varied from 50 to 405 ppm. Biogeochemical signatures of the bedrock mineralization in black spruce twigs produced greater anomaly to background contrasts for U and pathfinder elements (e.g., Be, Ag, Pb, Ca, and Sb) and correlated more precisely with the detected radiometric U/Th anomaly than did those of soil and humus. Principal component analysis of spruce twig data discriminated three major components, including plant nutrients, ore-related elements, and a mobile species. Uranium concentration varied from below detection limit to 23 ppm U in black spruce bark and from below detection limit in ∼40% of samples to 18 ppm in Labrador tea stem.
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10

Dampc, Anna, and Maria Luczkiewicz. "Labrador tea - the aromatic beverage and spice: a review of origin, processing and safety." Journal of the Science of Food and Agriculture 95, no. 8 (September 29, 2014): 1577–83. http://dx.doi.org/10.1002/jsfa.6889.

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11

Ouchfoun, Meriem, Hoda M. Eid, Lina Musallam, Antoine Brault, Shilin Li, Diane Vallerand, John T. Arnason, and Pierre S. Haddad. "Labrador tea (Rhododendron groenlandicum) attenuates insulin resistance in a diet-induced obesity mouse model." European Journal of Nutrition 55, no. 3 (April 28, 2015): 941–54. http://dx.doi.org/10.1007/s00394-015-0908-z.

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12

Никифоров, Aleksandr Nikiforov, Никифорова, and Antonina Nikiforova. "ANALYSIS OF SPATIAL DISTRIBUTION OF MEDICINAL PLANTS USING GIS-TECHNOLOGIES ON THE EXAMPLE OF LISINSKY SCIENTIFIC-EXPERIMENTAL FORESTRY." Forestry Engineering Journal 7, no. 1 (August 15, 2017): 88–95. http://dx.doi.org/10.12737/25198.

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Harvesting of medicinal-plant raw materials is one of the most promising areas for Russian producers, the market of which is characterized as developing one. Research on spatial analysis and definition of biological stock of medicinal-plant raw materials is made on the example of Lisinsky scientific-experimental forestry. The following medicinal plants: lily of the valley (Convallária majalis L.), St. John's wort (Hypéricum perforátum L.), valerian (Valeriána officinális L.), wood sorrel (Óxalis acetosella L.), Labrador tea (Ledum palustre L.), stinging nettle (Urtíca dióica L.) are widespread on the territory of the forestry and have potential commercial value. Data on stocks and territorial location of the medicinal plants were obtained with the use of geoinformation technologies. Biological stocks of medicinal raw materials is defined by the regional table for average long-term yield based on the types of growing conditions, forest types and taxonomic characteristics of plants. If we consider the maximum yield of one specific type of forest, we can say that Labrador tea and stinging nettle has the greatest mass. In the result, it was determined that harvesting of medicinal plants in the territory of forestry is possible for all the considered types of medicinal plants, which will increase the volumes of harvesting and storage of valuable raw materials. Inventory information and location of medicinal plants will enable to optimize the choice of the routes for the priority procurement of raw materials. Using GIS technology the total biological stock of the types of medicinal plants in Lisinsky scientific-experimental forestry was determined. Spatial analysis allowed determining the areas with the highest yield of medicinal plants. Geographic information systems can be used as a tool for monitoring, inventory, protection and organization of the industrial harvesting of medicinal raw materials. The developed technology can be used to determine the yield of mushrooms and wild berries.
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13

Krasnov, Volodymyr, Oleksandr Orlov, Oleh Zhukovskyi, Mariia Korbut, Iryna Davydova, Viktoriia Melnyk, and Olha Zborovska. "Comparing the radioactive contamination of marsh Labrador tea (Ledum palustre L.) Over different periods since Chernobyl accident." Eastern-European Journal of Enterprise Technologies 5, no. 10 (107) (October 31, 2020): 35–43. http://dx.doi.org/10.15587/1729-4061.2020.211933.

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14

Rapinski, Michel, Rui Liu, Ammar Saleem, John Thor Arnason, and Alain Cuerrier. "Environmental trends in the variation of biologically active phenolic compounds in Labrador tea, Rhododendron groenlandicum, from northern Quebec, Canada." Botany 92, no. 11 (November 2014): 783–94. http://dx.doi.org/10.1139/cjb-2013-0308.

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The impact of several environmental factors on the production of phenolic compounds in a North American medicinal plant, Labrador tea (Rhododendron groenlandicum (Oeder) Kron & Judd), was studied. Leaves were harvested in 2006 and 2010 over a latitudinal gradient in northern Quebec, and known phenolic markers were quantified by HPLC-DAD. The concentration of selected compounds varied geographically where they were higher between the 51st and 53rd parallel of northern Quebec and lower in the peripheral northern and southern region. Major variations were observed in the following marker compounds: (+)-catechin, (–)-epicatechin, quercetin-3-galactoside, and an undetermined quercetin-glycoside. The variation in phenolic compounds was best explained by short-term changes in annual temperature range and long-term estimates of insolation parameters such as solar radiation and photoperiod in the month of June.
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15

Black, Paleah, Lijie Niu, Manisha Sachdeva, David Lean, Raymond Poon, Wayne J. Bowers, Hing Man Chan, John T. Arnason, and Guillaume Pelletier. "Modulation of the effects of methylmercury on rat neurodevelopment by co-exposure with Labrador Tea (Rhododendron tomentosum ssp. subarcticum)." Food and Chemical Toxicology 49, no. 9 (September 2011): 2336–42. http://dx.doi.org/10.1016/j.fct.2011.06.035.

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16

Massicotte, H. B., L. H. Melville, and R. L. Peterson. "Structural characteristics of root–fungal interactions for five ericaceous species in eastern Canada." Canadian Journal of Botany 83, no. 8 (August 1, 2005): 1057–64. http://dx.doi.org/10.1139/b05-046.

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A combination of light microscopy (including differential interference contrast) and laser scanning confocal microscopy was used to document the colonization patterns of epidermal cells and details of intracellular hyphal complexes of five native ericaceous hosts: Vaccinium oxycoccos L. (bog cranberry), Ledum groenlandicum Oeder. (Labrador tea), Vaccinium myrtilloides L. (velvet-leaf blueberry), Kalmia angustifolia L. (sheep laurel), and Gaultheria procumbens L. (wintergreen). Colonization patterns, hyphal complex morphology, and the structure of thick-walled epidermal cells varied considerably among hosts. Multiple hyphal connections were observed between adjacent epidermal cells, indicating that one fungal entry point may result in the colonization of more than one epidermal cell. Further field observations combined with fungal isolations from field-collected plants, identification, and reinoculation studies of other species in the large Ericaceae family are required to determine the full range of structural details in ericoid mycorrhizas.Key words: ericoid mycorrhizas, hair roots, intracellular hyphal complexes, confocal microscopy.
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17

Shotyk, William, Muhammad Babar Javed, and Tommy Noernberg. "Trace elements in Labrador Tea (Rhododendron groenlandicum): How predominant sources to the plants impact the chemical composition of hot water extracts." Environmental Research 183 (April 2020): 109272. http://dx.doi.org/10.1016/j.envres.2020.109272.

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18

Holloway, Patricia S., and Mia R. Peterburs. "Propagation of Twelve Alaska Native Plants by Summer Stem Cuttings." Journal of Environmental Horticulture 27, no. 4 (December 1, 2009): 207–10. http://dx.doi.org/10.24266/0738-2898-27.4.207.

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Abstract Twelve Alaska native plants were propagated from softwood and semi-hardwood stem cuttings collected from late June through August. Cuttings of new growth were treated with 0.3% indole-3-butyric acid powder and propagated in horticultural grade perlite and vermiculite (1:1 by vol) under intermittent mist with bottom heat [26C (79F)] in a greenhouse with a minimum night temperature of 15C (59F). After 6 weeks, cuttings were harvested and evaluated for rooting percentage and root quantity. Four species rooted poorly (&lt; 25%) regardless of collection date: Siberian alder (Alnus viridis ssp. fruticosa), silverberry (Elaeagnus commutata), Bebb willow (Salix bebbiana) and shrub birch (Betula glandulosa). Best rooting (&gt; 80%) occurred June 20 for: Beauverd spiraea (Spiraea stevenii), sweetgale (Myrica gale), and thinleaf alder (Alnus incana ssp. tenuifolia). Peak rooting for dwarf birch (Betula nana), feltleaf willow (Salix alaxensis), balsam poplar (Populus balsamifera), Labrador tea (Ledum groenlandicum) and littletree willow (Salix arbusculoides) was early to mid July. During peak rooting times, all successful species developed adequate root quantities for survival following transplanting.
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19

Black, Paleah, Ammar Saleem, Andrew Dunford, José Guerrero-Analco, Brendan Walshe-Roussel, Pierre Haddad, Alain Cuerrier, and John Arnason. "Seasonal Variation of Phenolic Constituents and Medicinal Activities of Northern Labrador Tea,Rhododendron tomentosumssp.subarcticum, an Inuit and Cree First Nations Traditional Medicine." Planta Medica 77, no. 14 (April 6, 2011): 1655–62. http://dx.doi.org/10.1055/s-0030-1270968.

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20

Hébert, François, Nelson Thiffault, Jean-Claude Ruel, and Alison D. Munson. "Comparative physiological responses of Rhododendron groenlandicum and regenerating Picea mariana following partial canopy removal in northeastern Quebec, Canada." Canadian Journal of Forest Research 40, no. 9 (September 2010): 1791–802. http://dx.doi.org/10.1139/x10-124.

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In boreal black spruce ( Picea mariana (Mill.) BSP) dominated stands, careful logging around advance regeneration contributes to protect the shrub layer while increasing light availability. Therefore, it may promote expansion of bog Labrador tea ( Rhododendron groenlandicum (Oeder) Kron & Judd), which can impair black spruce growth by direct competition for nutrients and by alteration of soil biochemical conditions. Such harvesting approaches may not be suited for irregular, uneven-aged black spruce stands in the context of ecosystem-based management. Our objectives were to evaluate the effects of different intensities of partial harvest on critical resource availability and to compare the physiological and morphological responses of black spruce and Rhododendron to different intensities of partial harvest treatments. Two years after harvest, photosynthesis rate of black spruce was unchanged and was lower than that of Rhododendron, which was 63% higher after harvest. Nitrogen and water use efficiency were, respectively, 171% and 42% higher in Rhododendron than in black spruce after logging. Following harvest, black spruce physiology appeared to be regulated by the atmospheric humidity deficit, but for Rhododendron, physiology was regulated by light availability. The high plasticity of Rhododendron leaf traits could be indicative of the future advantage of this species in these stands following canopy removal associated with harvest.
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21

Li, Shilin, Antoine Brault, Mayra Sanchez Villavicencio, and Pierre S. Haddad. "Rhododendron groenlandicum(Labrador tea), an antidiabetic plant from the traditional pharmacopoeia of the Canadian Eastern James Bay Cree, improves renal integrity in the diet-induced obese mouse model." Pharmaceutical Biology 54, no. 10 (February 26, 2016): 1998–2006. http://dx.doi.org/10.3109/13880209.2015.1137953.

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22

Eid, Hoda M., Meriem Ouchfoun, Ammar Saleem, Jose A. Guerrero-Analco, Brendan Walshe-Roussel, Lina Musallam, Michel Rapinski, et al. "A combination of (+)-catechin and (−)-epicatechin underlies the in vitro adipogenic action of Labrador tea (Rhododendron groenlandicum), an antidiabetic medicinal plant of the Eastern James Bay Cree pharmacopeia." Journal of Ethnopharmacology 178 (February 2016): 251–57. http://dx.doi.org/10.1016/j.jep.2015.12.021.

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23

Ali, Md Hossen, Jean-Marie Sobze, Thu Huong Pham, Muhammad Nadeem, Chen Liu, Lakshman Galagedara, Mumtaz Cheema, and Raymond Thomas. "Carbon Nanotubes Improved the Germination and Vigor of Plant Species from Peatland Ecosystem Via Remodeling the Membrane Lipidome." Nanomaterials 10, no. 9 (September 16, 2020): 1852. http://dx.doi.org/10.3390/nano10091852.

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Application of the nanopriming technique to alleviate seed dormancy has shown promising results in various agricultural crop species. However, there is a dearth of knowledge regarding its potential use in native peatland boreal forest species to alleviate seed dormancy and improve their propagation or vigor for forest reclamation activities. Herein, we demonstrate the use of nanopriming with carbon nanotubes (CNT) to alleviate seed dormancy, improved seed germination, and seedling vigor in two boreal peatland species. Bog birch (Betula pumila L.) and Labrador tea (Rhododendron groenlandicum L.) seeds with embryo or seed coat dormancy were nanoprimed with either 20 or 40 µg/mL CNT, cold stratified at 2–4 °C for 15 days, and allowed to germinate at room temperature. The emerged seedlings’ lipidome was assessed to decipher the role of lipid metabolism in alleviating seed dormancy. We observed significant (p < 0.05) improvement in seedling germination and seedling vigor in seeds primed with multiwalled carbon nanotubes functionalized with carboxylic acids. Phosphatidylcholine (PC 18:1/18:3), phosphatidylglycerol (PG 16:1/18:3), and lysophosphatidylcholine (LPC 18:3) molecular species (C18:3 enriched) were observed to be highly correlated with the increased seed germination percentages and the enhanced seedling vigor. Mechanistically, it appears that carbon nanoprimed seeds following stratification are effective in mediating seed dormancy by remodeling the seed membrane lipids (C18:3 enriched PC, PG, and LPC) in both peatland boreal forest species. The study results demonstrate that nanopriming may provide a solution to resolve seed dormancy issues by enhancing seed germination, propagation, and seedling vigor in non-resource boreal forest species ideally suited for forest reclamation following anthropogenic disturbances.
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24

Yamamoto, K. C. M., E. Y. T. Silva, K. N. Costa, M. S. Souza, M. L. M. Silva, V. B. Albuquerque, D. M. Pinheiro, D. G. Bernabé, and V. N. L. S. Oliva. "Avaliação fisiológica e comportamental de cães utilizados em terapia assistida por animais (TAA)." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 64, no. 3 (June 2012): 568–76. http://dx.doi.org/10.1590/s0102-09352012000300007.

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Realizou-se a observação comportamental de nove cães terapeutas (oito da raça Labrador Retriever e um Golden Retriever), dosaram-se cortisol sérico e salivar, aferiram-se a temperatura retal, a pressão arterial sistólica e as frequências cardíaca e respiratória nos seguintes momentos: M0 (média de três avaliações do cão em repouso) e em M1, M2 e M3 (imediatamente antes, imediatamente após e decorridas 24h das atividades de terapia assistida por animais - TAA), respectivamente. Não houve diferença significativa quanto às características estudadas (P>0,05), exceto pela temperatura, que foi mais elevada em M1 e M2 do que em M0 (P=0,009). A avaliação comportamental, realizada de maneira descritiva, não apresentou alteração negativa. Houve diferença significativa quanto à concentração de cortisol sérico entre os momentos M1 e M3 (P=0,071), e não ocorreu diferença da concentração do cortisol salivar entre os quatro momentos (P=0,746). As alterações observadas foram atribuídas à contenção e à manipulação dos animais e não desencadearam desconforto físico ou estresse dignos de nota em cães.
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25

Dechsri, Precharn, Loretta L. Jones, and Henry W. Heikkinen. "Effect of a labratory manual design incorporating visual information-processing aids on student learning and attitudes." Journal of Research in Science Teaching 34, no. 9 (November 1997): 891–904. http://dx.doi.org/10.1002/(sici)1098-2736(199711)34:9<891::aid-tea4>3.0.co;2-p.

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Sheik, Matthew L., Kitty L. LaBounty, Erika Mitchell, and Emily L. Gillespie. "Fourteen polymorphic microsatellite markers for the widespread Labrador tea ( Rhododendron groenlandicum )." Applications in Plant Sciences 7, no. 12 (December 2019). http://dx.doi.org/10.1002/aps3.11306.

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27

Singh, Bhuwanendra, Jitendra Gupta, Rohit Mohan, Reena Gupta, and Kanchan Pal. "Hypouricemic Significance of Ledum Palustre (Marsh Tea): A Review." Research Journal of Pharmacy and Technology, May 26, 2021, 2907–12. http://dx.doi.org/10.52711/0974-360x.2021.00510.

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The current review article is based on the facts to reveal the biological potentials of the genus ledum, and specie palustre. Although in the article all the species are well described with their distribution in all over the world and their pharmacological activities are also discussed. Rhododendron tomantosum is also known as Marsh Tea or northern Labrador tea, which is an evergreen shrub having the height of about 40 cm and the plant has about ten species in all over the world. Article has very informative aspect regarding Hypouricemic Significance of Ledum palustre (L. palustre), its chemical compounds extracted and analyzed by different spectroscopic and chromatographic techniques to report the active principles from the oil of the Rhododendron tomantosum fresh leaves. The main active compounds were found are given as (41.0–43.4%) ledol (23.3–26.7%) and ascaridole (15.1–4.5%). L. palustre has a very significant role in the gout and arthritis occurs due the presence of high amount of uric acid in the blood plasma. Various dosage forms are mentioned in the review article to explore the potentials of the drug. Hence according to literature if L. palustre is significantly capable to reduce the high level of the uric acid if give in the potency if 30 c (diluted 30 times)) and 1 M ((1000 dilutions) to the patients, and may be a good alternative to the allopurinol. So, this drug is frequently used in the homeopathic system of medicine to get the hypouricemic significance in the human beings.
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Fadaei, Sepideh, Shanjida Khan, Michelle Young, Ira Sherr, and Janusz J. Zwiazek. "Impact of soil stockpiling on ericoid mycorrhizal colonization and growth of velvetleaf blueberry ( Vaccinium myrtilloides ) and Labrador tea ( Ledum groenlandicum )." Restoration Ecology, November 16, 2020. http://dx.doi.org/10.1111/rec.13276.

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