Log in

Relevant bibliographies by topics / Lactone reduction / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Lactone reduction.

Dissertations / Theses on the topic 'Lactone reduction'

Author: Grafiati

Published: 4 June 2021

Last updated: 17 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 18 dissertations / theses for your research on the topic 'Lactone reduction.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Collins, Karl Daniel. "The development and application of radical and anionic cyclisations mediated by samarium(II) diodide and protic co-solvents." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/the-development-and-application-of-radical-and-anionic-cyclisations-mediated-by-samariumii-diodide-and-protic-cosolvents(0e807a8c-d40f-45bb-8d83-26e79ebe9388).html.

Full text

Abstract:

The development of selective SmI2-H2O-mediated mono-reductions of cyclic-1,3-diesters to the corresponding 3-hydroxy acids is described. The reaction proceeds with complete selectivity for cyclic-1,3-diesters over acyclic esters. Sequential one-pot conjugate reduction-ester reduction of alkylidene cyclic-1,3-diesters is also reported. Furthermore, we describe the exploitation of the unusual ketyl radical intermediates formed via single electron reduction of the ester carbonyl in unprecedented 5-exo-trig cyclisations providing access to highly substituted, stereo-defined, cyclopentanols and cyc

APA, Harvard, Vancouver, ISO, and other styles

2

Hutt, Jean. "Synthese d'analogues de la vitamine d::(3) : synthese chirale de composes polyhydroxyles." Université Louis Pasteur (Strasbourg) (1971-2008), 1986. http://www.theses.fr/1986STR13326.

Full text

Abstract:

La transformation de la cfarvone en quatre diastereoisomeres precurseurs du cycle a des dihydrovitamines et dihydrotachysterols est decrite dans la premiere partie. Par couplage d'un acetylure derive des cycles c/d de la vitamine d::(3) avec la cetone precurseur du cycle a, puis sa formation du systeme dienique a l'aide de titane a basse valence nous avons obtenu des dihydrotachysterols majoritairement. D'un autre cote, l'utilisation de sulfoxydes optiquement actifs dans l'intention de creer des centres hydroxyles chiraux et son application a la synthese du fragment polyhydroxyle de l'amphoter

APA, Harvard, Vancouver, ISO, and other styles

3

Parmar, Dixit. "Reductive cyclisations of lactones using SmI2 and H2O." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/reductive-cyclisations-of-lactones-using-smi2-and-h2o(533c0430-fd14-4a24-93f2-18a7fb27232f).html.

Full text

Abstract:

Carbonyl reduction is a fundamental transformation that underpins synthetic chemistry. The re-routing of carbonyl reduction through less-conventional intermediates allows new selectivity and reactivity to be found in the resulting reaction space. We have shown for the first time that the unusual radical anions formed by electron transfer to the ester carbonyl group can be exploited in additions to alkenes. We have demonstrated that the reductive cyclisations of lactones, triggered by electron-transfer from SmI2-H2O, allow for highly decorated cyclopentane and cycloheptane ring systems to be co

APA, Harvard, Vancouver, ISO, and other styles

4

Fernandez, Anne-Marie. "Préparation de γ-butyrolactones γ-alkylées optiquement pures à partir de l'acide L-tartrique. Application à la synthèse totale de la L-bioptérine". Rouen, 1996. http://www.theses.fr/1996ROUES025.

Full text

Abstract:

Une nouvelle méthode pour la préparation de gamma-butyrolactones optiquement pures est proposée. Une stratégie de synthèse donnant accès à deux types de chirons carbonylés (cétones et aldéhyde) a permis le développement de deux réactions hautement stéréosélectives créant ainsi un troisième centre stéréogénique : la réduction des cétones, (2R, 3R)-2,3-dipivaloxy-4-oxo alcanoates de méthyle par le borohydure de sodium dans le méthanol mène aux alcools correspondants (4R), avec des ee>98%, précurseurs des (2R,3S,4R)-2,3-dipivaloxy-4-alkylbutyrolactones. L'addition d'organomagnésiens sur l'aldéhyd

APA, Harvard, Vancouver, ISO, and other styles

5

Anderson, Scott Cameron. "Blood lactate reduction at three recovery intensities following severe rowing excercise." Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/26348.

Full text

Abstract:

The purpose of this study was to observe the differences in rates of blood lactate reduction (BLR) at three recovery intensities (40% VO₂max, 60% V02max, and combined recovery ) when subjects are highly trained and aerobically fit. Eight well-trained oarsmen (age = 23.2 yr, Ht = 189.6 cm, Wt = 85.3 kg, VO₂max = 5.2 1 / min or 61.6 ml / kg min⁻¹) were tested in one pre-experimental procedure and three experimental treatments. The pre-experimental procedure involved the determination of VO₂max, and the loads at which 40 -, 50 -, and 60% VO₂max occurred from a progressive load VO₂max. The th

APA, Harvard, Vancouver, ISO, and other styles

6

Yalavac, Irem. "Assessing the scope of reductive cyclisations of lactones using SmI2-H2O." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/assessing-the-scope-of-reductive-cyclisations-of-lactones-using-smi2h2o(7a7988bd-609c-4ab2-b541-6106bb7a3fb7).html.

Full text

Abstract:

This report firstly describes the 5-exo-dig,6-exo-trig cascade cyclisation of 6-membered allenyl lactones for the formation of highly decorated 7,6-fused bicycles using the SmI2-H2O reducing system. Preliminary studies showed that 5-exo-dig,5-exo-trig cascade reactions successfully yield 7,5-fused bicycles. However, performance of 6-exo-trig reactions of this type with SmI2 has little literature precedent and was not known to proceed with SmI2 in combination with H2O.In order to investigate the cascade cyclisations, cis and trans allenyl lactones with alkene or alkyne chains tethered at the 2-

APA, Harvard, Vancouver, ISO, and other styles

7

Hateley, Martin John. "Studies in the dehydrogenase catalysed reduction of 2-ketocarboxylic acids." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299531.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

SAKELLARIOU, FARGUES REINE. "Reactivite chimique et photochimique d'alpha -enones dans les milieux organises." Toulouse 3, 1986. http://www.theses.fr/1986TOU30044.

Full text

Abstract:

Dans une premiere partie on determine les zones monophasiques des diagrammes des phases pseudoternaires de plusieurs microemulsions. Dans l'une d'elles l'isophorone remplace l'huile. Ensuite les chapitres ii et iii sont consacres aux reactions de photocycloaddition (a+a, a+b) d'alpha -enones (isophorone, coumarine, dimethylthymine). On montre que les phenomenes observes sont lies aux differentes localisations possibles des substrats, aux mecanismes de reaction et aux structures des milieux. En conclusion, la localisation des reactifs a l'interface permet la combinaison des effets de concentrat

APA, Harvard, Vancouver, ISO, and other styles

9

Duffy, Lorna A. "From spirocyclisations to ring-size selective reductions : the effect of co-solvent on the chemistry of SMI₂." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496693.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Nlooto, Manimbulu. "Effect of stavudine dosage reduction on the incidence of symptomatic hyperlactataemia/lactic acidosis in adults female HIV/AIDS infected patients treated at Dr George Mukhari Hospital." Thesis, University of Limpopo (Medunsa Campus), 2010. http://hdl.handle.net/10386/216.

Full text

Abstract:

Theses (Msc.(Med.)(Pharmacy))--University of Limpopo, 2010.<br>With the availability of Highly Active Antiretroviral Therapy (HAART), one of the limitations of treatment safety is the occurrence of adverse events associated with antiretroviral agents. The aim of this study was to establish whether stavudine dosage reduction prevents toxicity from developing and minimizes the incidence of symptomatic hyperlactataemia/lactic acidosis (LA) in adults female HIV/AIDS infected patients. This retrospective study covered adult patients treated at the adult ARV clinic, Dr George Mukhari Hospital

APA, Harvard, Vancouver, ISO, and other styles

11

Tshibangu, Israel. "Investigating the cause of reduction of lactate production in Panc-1 cell lines when subjected to digitoxin." Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-20116.

Full text

Abstract:

Pancreatic ductal adenocarcinoma (PDAC) yet remains one of the top 10 most prevalent and top five most common cause of cancer-related deaths solely in the United States. Its metastatic deviation from most cancer types rends it one of the most subtle yet perturbating disease. Hope lies within the traces of reproducibly mutated genes which are said to be found in nearly 95% of all PDAC. This study aimed to examine how digitoxin affects glycolysis and gene expression in Panc-1 cell lines. Panc-1 cells were cultured and treated with various concentrations of digitoxin for 24h-48h depending on the

APA, Harvard, Vancouver, ISO, and other styles

12

Kissell, Sarah M. "Comparing the Effect of Carbon Sources, Lactate and Whey, on Biological Reductive Dechlorination of TCE in Laboratory Flow Through Columns." DigitalCommons@USU, 2017. https://digitalcommons.usu.edu/etd/5394.

Full text

Abstract:

Trichloroethylene (TCE) is a chlorinated solvent most commonly used as an industrial degreaser for cleaning mechanical equipment. Historic improper management and disposal of TCE has resulted in contaminated soil and groundwater across the United States, including Hill Air Force Base in Utah. The abundance of TCE in the environment presents a public health risk because it is categorized as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC). The purpose of this study was to improve the bioremediation techniques of biostimulation and bioaugmentation. A continuous flow

APA, Harvard, Vancouver, ISO, and other styles

13

Belotti, Damien. "Cyclisation photoreductrice de cetones insaturees, applications : syntheses totales de l'hirsutene et de l'actinidine." Reims, 1988. http://www.theses.fr/1988REIMS006.

Full text

Abstract:

L'irradiation de cetones delta ,epsilon -insaturees en presence de donneurs d'electrons tels que l'hmpt et la triethylamine donne une cyclisation photoreductrice menant a des cyclopentanols. Generalisation de cette reaction a des cetoamides : obtention d'aza-3 bicyclo(4. 3. 0) nonanes

APA, Harvard, Vancouver, ISO, and other styles

14

Goran, Benedeković. "Enantiodivergentna totalna sinteza odabranih stiril laktona i preliminarno ispitivanje njihove citotoksičnosti." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2012. http://dx.doi.org/10.2298/NS20121011BENEDEKOVIC.

Full text

Abstract:

U radu je ostvarena enantiodivergentna totalna sinteza oba enantiomera goniofufurona, 7-epi-goniofufurona i krasalaktona C polazeći iz D-glukoze. Ključne faze u sintezi 7-epi-(+)-goniofufurona bile su stereoselektivna adicija fenilmagnezijum bromida na aldehidnu grupu pogodno za&scaron;tićene dialdoze, i stereospecifično formiranje furano-laktonskog prstena ciklokondenzacijom odabranog hemiacetalnog derivata sa Meldrum-ovom kiselinom. Sinteza (+)-goniofufurona i (+)-krasalaktona C zahtevala je inverziju konfiguracije na C-5u zajedničkom intermedijeru, koja je efikasno ostvarena u uslovima Mits

APA, Harvard, Vancouver, ISO, and other styles

15

Wang, I.-Hsuan, and 王宜瑄. "Samarium diiodide-mediated reductive cyclization in spiranes and tricyclic lactones synthesis." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/34859101199502689565.

Full text

Abstract:

碩士<br>國立中正大學<br>化學暨生物化學研究所<br>100<br>This thesis describes a methodology to access spiro compounds in a rapid and efficient manner. The ring size of the spiro compounds were controlled by altering the length of the side chain, and afforded various spirocyclic compounds. The ,-unsaturated ester-aldehydes which were prepared from cycloalkenes via a four-step sequence -carbomethoxylation, triflation, replacement and hydrolysis, were subjected to samarium diiodide-mediated and obtained various spirocyclic and tricycliclactone compounds in good yields.

APA, Harvard, Vancouver, ISO, and other styles

16

Wang, Chun-Chih, and 王俊智. "Cobalt-Catalyzed Highly Regio- and Stereoselective Reductive Ene-Ene and Ene-Yne Coupling Reactions: Application in the Synthesis of Lactones, Lactams and Macrocyclic Lactones." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/32656386242429095336.

Full text

Abstract:

博士<br>國立清華大學<br>化學系<br>92<br>In this work, we report two cobalt-catalyzed olefins dimerization modes: (a) reductive dimerization of conjugated alkenes to yield directly the saturated linear diesters, dinitrile, and disulfone 2a-2g, offering a more convenient method to the synthesis of adipic acid and, (b) cobalt-catalyzed head-to-tail dimerization of vinylarenes 4a-4l in good yields. On the other hand, we have recently developed a reaction mode of cobalt-catalyzed tail-to-tail reductive dimerization of conjugated alkenes. This provides an efficient and mild route for the corresponding saturate

APA, Harvard, Vancouver, ISO, and other styles

17

Liu, Yi-Chang, та 劉易昌. "Preparation of [(MMPEP)Al(μ-OR)]2 and its Application in the Ring-Opening Polymerization of ε-caprolactone and L-Lactide and MPV Reduction of Aldehydes and Ketones". Thesis, 2001. http://ndltd.ncl.edu.tw/handle/17482309843980083728.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Stejskal, Vojtěch. "Kombinovaná metoda - Sanace podzemních vod za využití kombinace laktátu sodného a nanoželeza." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-332378.

Full text

Abstract:

Vojtěch Stejskal - Diplomová práce 2014 - Přírodovědecká fakulta UK v Praze 4 ABSTRACT The thesis describes pilot applications of combined method - combination of sodium lactate and nanoparticles of zero-valent iron and their synergic effect. Two applications of combined method are described onto two geologically different sites - in Rožmitál pod Třemšínem and Spolchemie in Ústí nad Labem. First site is contaminated by polychlorinated biphenyls; contamination is situated in hydraulically well conducted porous media formed by weathered granodiorite. Main contaminants of Spolchemie site are tric

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!