To see the other types of publications on this topic, follow the link: Lagging.
Dissertations / Theses on the topic 'Lagging'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 47 dissertations / theses for your research on the topic 'Lagging.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
1
Holl, Adelheid. "Transport infrastructure in lagging European regions." Thesis, University of Sheffield, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369853.
Full text
2
Chiu, Kwong-Shing Kevin. "Temperature dependent properties and microvoid in thermal lagging /." free to MU campus, to others for purchase, 1999. http://wwwlib.umi.com/cr/mo/fullcit?p9962510.
Full text
3
Kemp, Harriet. "Lagging strand replication creates evolutionary hotspots throughout the genome." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/17896.
Full textAbstract:
The rate of DNA mutation is known to fluctuate across the genome but the patterns of mutation rate variation and molecular causes are poorly defined. It is important to understand these patterns of mutation as they influence where deleterious mutations are likely to arise and how rapidly sequences are likely to accumulate change between species, a measure often used as a proxy for functional constraint. In this work I investigate the relationship between DNA replication and apparent mutation hotspots adjacent to transcription factor binding sites. In eukaryotes both DNA strands are replicated simultaneously, the leading strand as a continuous stretch and the lagging strand as a series of discrete Okazaki fragments that are subsequently ligated together. Some transcription factors are able to bind the DNA lagging strand during replication and act as a partial barrier to DNA polymerase, resulting in the accumulation of Okazaki fragment junctions adjacent to these sites. I find that mutation rate is correlated genome wide with Okazaki junction frequency, suggesting that Okazaki junction processing may be error-prone. We present a mechanistic hypothesis to explain this locally elevated mutation rate and propose a role for lagging strand replication and its error-prone Pol α tract retention in the formation of these hotspots. I test this hypothesis using Okazaki fragment sequencing data from the yeast Saccharomyces cerevisiae to identify peaks in Okazaki junctions. When these peaks are aligned and orientated, so that the direction of lagging strand replication is uniform, I find a peak in substitution rate immediately downstream of Okazaki junctions, precisely where Pol α tract retention is predicted to occur. Novel binding motifs are identified within the underlying DNA of these junctions that can be assigned to known strong and fast-binding transcription factors, previously implicated in the phasing of nucleosomes, such as Reb1. I show that mutation hotspots adjacent to transcription factor binding sites are a conserved feature of eukaryotic genomes. In the human genome I predict sites of preferential Pol α retention using DNase I hypersensitivity footprint data. We observe that those footprints predicted as germline-specific manifest an elevated mutation signature. I propose that the rapid binding of some transcription factors to DNA following replication is required for nucleosome positioning or other important functions, however this incurs a cost in terms of locally elevated mutation rate adjacent to and within the sequence specific binding site. As a consequence these binding sites are biologically important mutational hotspots whose functional significance has been systematically underestimated by standard measures of sequence constraint.
4
Cao, Xiaopeng. "A PARALLEL APPROACH TOWARDS CORRELATION MEASUREMENT GENE PAIRS WITH TIME-LAGGING EXPRESSION BEHAVIORS." Available to subscribers only, 2009. http://proquest.umi.com/pqdweb?did=1967969531&sid=1&Fmt=2&clientId=1509&RQT=309&VName=PQD.
Full text
5
D'Amanda, Kevin J. "Computer aided design of soldier pile and lagging retaining walls with tieback anchors." Thesis, Springfield, Virginia: Available from National Technical Information Service, 1991. http://hdl.handle.net/10945/28054.
Full text
6
Kopainsky, Birgit [Verfasser]. "A system dynamics analysis of socio-economic development in lagging Swiss regions / Birgit Kopainsky." Aachen : Shaker, 2005. http://d-nb.info/1181612284/34.
Full text
7
Hinerman, Jennifer M. "The Study of Protein-Protein Interactions Involved in Lagging Strand DNA Replication and Repair." Connect to full text in OhioLINK ETD Center, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1216824884.
Full textAbstract:
Thesis (Ph. D.)--University of Toledo, 2008.Typescript. "Submitted as partial fulfillment of the requirements for the Doctor of Philosophy in Chemistry." Includes bibliographical references (leaves 245-252).
8
Jakobsson, Catrin, Daniel Edvardsen, and Ola Henriksson. "Foreign Exchange Risk Management Practices : A Study of Swedish Medium- and Large-sized Companies." Thesis, Jönköping University, JIBS, Business Administration, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-11499.
Full textAbstract:
Purpose: The purpose of the thesis is to describe which foreign exchange risk techniques that are used by medium- and large-sized Swedish companies within the Jönköping region, and how they as well as a bank evaluate the techniques in the current recession.
Background: The reason why companies decide to expand their operations abroad is to take advantage from imperfections in other national markets. The fluctuations in currencies and exchange rates can have a huge effect on a company’s cash flows when doing business abroad. Therefore, when companies manage their foreign exchange risk, they have to be familiar with all the methods and tools available in order to pick the ones that best suit their needs.
Method: We sent out a questionnaire and got it answered by eight companies within the Jönköping region regarding their strategy when managing foreign exchange risk. We have also interviewed a financial adviser, working at Handelsbanken, regarding the techniques offered to companies. A “foreign currency table” located in Linköping, was also contacted. They are in charge of creating recommendations and products sold by Handelsbanken.
Conclusion: Hedging is the most frequently used tool by the companies in our study. Leading and lagging strategies are used quite often, while swaps and invoice currency is used less frequently by them. Exposure netting and cash pooling does not seem to be used at all. We believe that companies generally should seek more information on new techniques introduced in the market and be open to new possibilities and solutions for managing currency risk. Most of the companies in our sample, according to us, are too comfortable in their choice of techniques.
Syfte: Syftet med denna uppsats är att beskriva vilka valutarisk tekniker som används av medelstora och stora företag inom Jönköpings området, samt hur dessa företag och en bank utvärderar teknikerna i den rådande lågkonjunkturen.
Bakgrund: Anledningen till varför företag väljer att expandera utomlands är för att ta nytta av fördelar som uppstår i andra marknader. Fluktuationer i valutor och valutakurser kan ha stor effekt på företagens kassaflöden när handel utomlands utförs. När företag hanterar sin valutarisk måste de vara familjära med de olika metoder som finns tillgängliga, för att få reda på vilka av dessa som bäst tillgodoser deras behov.
Metod: Åtta företag inom Jönköpings regionen, svarade på ett formulär, angående deras strategi när det kommer till hantering av valutarisk. Vi har även intervjuat en företags rådgivare på Handelsbanken, angående teknikerna som de erbjuder företagen. Valutabordet i Linköping har också blivit kontaktat. De har till uppgift att ta fram rekommendationer och produkter som säljs av Handelsbanken.
Slutsats: Hedging är den teknik som används mest av företagen i vår undersökning. Leading och lagging används rätt så ofta, medan swaps och invoice currency används mer sällan av dem. Exposure netting och cash pooling tycks inte användas alls. Vi anser att företag generellt ska eftersöka mer information om nya tekniker som introduceras på marknaden samt vara öppna för nya möjligheter och lösningar till att hantera valutarisk. De flesta av de undersökta företagen anser vi i dagsläget är för bekväma i sina val av tekniker.
9
Dresdner, C. Jorge D. "The structuralist theory of inflation and structural inflation in Chile, 1950-1972 the lagging food hypothesis revisited /." Uppsala : Stockholm : Academiae Ubsaliensis ; Distributor, Almqvist & Wiksell, 1990. http://catalog.hathitrust.org/api/volumes/oclc/23613795.html.
Full text
10
Rannou, Olivier. "Identification and biochemical characterization of a lagging-strand specific replication sub-complex with the helicaseprimase- polymerase enzymes." Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604301.
Full textAbstract:
DNA replication is the most fundamental process in all living species. Faithful replication and regulation are crucial for genome stability. Replisomes are protein assemblies that replicate DNA: they unwind double stranded DNA, synthesize RNA primers on the leading strand and lagging strand, and synthesize new DNA. The replisome of the low G + C content Gram-positive bacteria such as Bacillus subtilis contains two different DNA polymerases: a processive high-fidelity replicative polymerase PolC on the leading and lagging strand, and an error-prone DnaE on the lagging strand, which extends RNA primers before hand-off to Pole. We found that DnaE interacts with the helicase DnaCBs and the primase DnaG, and that these proteins form a complex in vitro. These interactions, which position DnaE in the lagging strand half of the replisome as expected from previous studies, are analysed in more detail here. We show that protein-protein interactions within binary complexes and ternary complexes formed by DnaE, DnaG and DnaCBs are functionally relevant. DnaE partially inhibits the helicase and the primase activities, while DnaCBs and DnaG stimulate each other's activities. Neither the helicase nor the primase had any effect on DnaE polymerase activity; but, they improved its fidelity, likely via allosteric effects induced by direct proteinprotein interactions that lower the efficiency of nucleotide mis-incorporation in the catalytic site of DnaE. These regulations within the replisome lagging strand subunit might participate in the synchronization of synthesis of the lagging-strand synthesis with the leading-strand, and improve the fidelity of lagging strand synthesis. This, and the possible roles of DnaE in other events related to DNA synthesis related events are discussed here.
11
Nykvist, Marcus, and Eric Månsson. "The Stock Market as a Leading Macroeconomic Indicator." Thesis, Linnéuniversitetet, Institutionen för ekonomistyrning och logistik (ELO), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-106644.
Full textAbstract:
This article goes on to explain and seek if there is any predictive power in the stock markets toward GDP. Put in other words, this study examines whether or not the stock market can be seen as a leading indicator toward GDP for the ten biggest economies measured by GDP in the year 2020. What can be concluded from the results discussed in the analysis section is that the best predictability is when the stock market leads GDP with three to five quarters. In earlier studies on the same topic, the same results can be concluded. However, these previous studies have all shown an extended predictive period between one and five quarters, compared to our results which showed three to five quarters. One note worth mentioning is that we obtained contradictory results depending on if the tests were implemented for each country individually through time series data analysis, or collectively through panel data analysis. Our conclusion was drawn with the panel data analysis as the underlying truth, as it is viewed as more efficient and informative while also being a more suitable tool for studying the dynamics of change.
12
Arif, Safin. "Utveckling av Key Performance Indicators genom underhållstrategi för processindustrin." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-46693.
Full textAbstract:
Följande avhandlingsarbete har utförts som en fallstudie på BillerudKorsnäs tillsammans med en litteraturstudie som har gett upphov till den teoretiska referensram som grundläggande lagt grunden för mätstrukturen Key Performance Indicators (KPI) utformad för underhållsorganisationen. Vidare har datainsamling i form av intern och extern benchmarking tillsammans med dokumentstudier, semistrukturerade intervjuer och strukturerade observationer genomförts för att få en fullständig redogörelse för den aktuella situationen i enlighet med riktlinjerna för examensarbete på högskolenivå. Examensarbetet täcker ämnet för underhållsteknik och syftar till att kartlägga underhållsstrategin för att kunna utforma en Key Performance Indikator (KPI: s) mätstruktur för BillerudKorsnäs. Examensarbetet ger därefter upphov till analysavsnittet som med stöd av den teoretiska referensramen redogör för det förbättringsförslag och framtida rekommendationer att belysa för ett underhåll och driftsäkerhet i världsklass. Studien framställer underhållsverksamheten med utgångspunkt från svensk standard och en ledande och eftersläpande mätetalsstruktur som vetenskapligt underlag. Detta har resulterat i en tydligt definierat underhållsstrategi med nyckeltalsprestationer för en underhållsorganisation där underhållstrategin är kopplad till företagets vision och strategi. Frågeställningen som är kopplad till problemformuleringen genomsyrar arbetet och handlar om att redogöra för hur man kan anknyta till underhållstrategin och redogöra för vilka KPI:er som skall redovisas, för att skapa en effektiv och produktiv underhållsverksamhet som arbetar i enlighet med de mål man satt upp på BillerudKorsnäs- Sulfatfabrik. Resultatet från det bedrivna arbetet visar att KPI-strukturen inte är i enlighet med den underhållstrategi BillerudKorsnäs på koncernnivå fastställt, vidare så påvisar nyckeltalen inte ett effektmätetal relevant för underhållsverksamheten och fabriksledningen. Genom förbättringsförslaget som föreslås tas en ny KPI-struktur fram som ger en mätbarhet till underhållsverksamheten och är kopplad till BillerudKorsnäs vision och strategi för ”Bästa arbetsätt” inom underhåll och driftsäkerhet i världsklass.The following thesis work has been carried out as a case study at BillerudKorsnäs together with a literature study which has given rise to the theoretical frame of reference which fundamentally laid the foundation for the Key Performance Indicators (KPI’s) measurement structure designed for the company. Furthermore, data collection in the form of internal and external benchmarking together with document studies, semi-structured interviews and structured observations has been carried out in order to get a complete view of the current situation as possible in accordance with the guidelines for scientific research approach. The research covers the subject area of maintenance technology and aims to map the maintenance strategy to be able to design a (KPI’s) measurement structure for BillerudKorsnäs maintenance organization. The thesis then gives rise to the analysis section which, with the support of the theoretical frame of reference, describes the improvement proposals and future recommendations to elucidate world-class maintenance and reliability. The study presents maintenance operations based on Swedish standards and “leading and lagging” measurement structure as a scientific basis. This has resulted in a defined metric structure with key performance measures for a maintenance organization where the maintenance strategy is connected to the company's vision and strategy. The question linked to the problem formulation permeates the research and is about explaining how to link to the maintenance strategy and describing which KPIs are to be reported, in order to create an efficient and productive maintenance organization that functions in accordance to the maintenance goals set on BillerudKorsnäs- Sulfatfabrik. The results of the conducted research show that the KPI- structure has not been established in accordance with BillerudKorsnäs' maintenance strategy at a cooperation level, furthermore, the key figures do not show an effect metric relevant to the maintenance operations and the factory management. The proposed improvement proposal proposes a new KPI- structure that provides measurability to the industrial maintenance operation and is symmetrical with BillerudKorsnäs vision and strategy for "Best working methods" in world-class maintenance and reliability.
13
Steinert, Martin. "UMTS - the lagging adoption of a network system innovation : a hypothesis generating empirical study, exploring which factors influence European companies' usage and investment behaviour towards packet switched mobile data services /." Friburg/Switzerland : IIMT University Press, 2006. http://aleph.unisg.ch/hsgscan/hm00192755.pdf.
Full text
14
Enehag, Ellenor. "Helping our students with behavioral challenges by using the ALSUP/CPS and SNAP models." Thesis, Malmö universitet, Fakulteten för lärande och samhälle (LS), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-28830.
Full textAbstract:
This paper presents a study of the ALSUP/CPS (The Assessment of Lagging Skills andUnsolved Problems/Collaborative & Proactive Solutions) work primarily conducted on astudent who was facing the difficulty of changing from one mind set to the current lesson.The objective of the study is to investigate and compare the outcomes of the ALSUP/CPSwork by interviewing the student, 3 teachers and the school psychologist. The outcomes ofstudent interview were compared to outcomes that emerged from the teachers interviews andthe school psychologist. The patterns that emerged showed both positive and negative results.The analysis revealed patterns that were significant to both the student and the teachers. Thestudent noticed that his behaviour changed in class which was also highlighted by all threeteachers. It also showed that the student was able to recognize his behaviour and therebymake suggestions for improvement. The ALSUP/CPS model emerged as an evidence-basedtool that is effective in investigating and gauging the student potential to recognize andovercome difficulties. The SNAP (Special Needs Assessment Profile) model underscored thefact that it would be a good and supportive tool to use for identifying the academic difficultiesthat a student may be facing; therefore, both the ALSUP/CPS and SNAP would complementeach other in the areas of behavioural and academic difficulties.
15
Almeida, Alex Garcia de. "Identificação de indicadores globais para o monitoramento da segurança de processos de plataformas de produção de petróleo e gás natural: estudo de caso da indústria brasileira." Universidade do Estado do Rio de Janeiro, 2013. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=5942.
Full textAbstract:
Este trabalho verificou o tema de segurança de processos no segmento de plataformas de produção de petróleo e gás no mar de forma a propor um modelo de indicadores globais a fim de facilitar a identificação de fragilidades no gerenciamento de riscos de processos da indústria de produção de petróleo e gás natural no mar. O resultado esperado é o fornecimento de dados para a otimização de recursos regulatórios na busca da melhoria da segurança operacional. Para tal, buscando conhecer a postura das empresas no cumprimento da necessidade regulamentar da implementação de um Sistema de Gestão de Segurança de Processos (SGSP), foram identificadas as principais práticas preventivas para a o gerenciamento de riscos. Por conseguinte, mensurou-se o esforço na implementação deste SGSP como correlação direta para a prevenção de acidentes (foco preventivo). Já a análise dos resultados deste gerenciamento de riscos (foco reativo) foi obtido através incidentes operacionais classificados de acordo com sua respectiva importância/impacto, dentro de linhas de corte pré-estabelecidas. Assim, o indicador Global preventivo (IGPRV) e o Indicador Global reativo (IGRTV) foram elaborados agregando diferentes indicadores específicos de cada segmento para simplificar a análise e incluir a articulação de conceitos de segurança de processos à atuação regulatória. Os indicadores globais propostos quantificam conceitos subjetivos e complexos para o estabelecimento de metas e permitem aferir o desempenho das ações e projetos da regulação da indústria. Também permitem a identificação e a disseminação das melhores práticas de gerenciamento de riscos, comparando-as em diferente níveis de gerenciamento. Na análise dos resultados, pôde-se perceber que a utilização dos indicadores globais propostos pode responder com sucesso às necessidades regulatórias identificadas
16
Juglaret, Frédéric. "Indicateurs et tableaux de bord pour la prévention des risques en santé-sécurité au travail." Phd thesis, Ecole Nationale Supérieure des Mines de Paris, 2012. http://pastel.archives-ouvertes.fr/pastel-00819109.
Full textAbstract:
S'il est acquis depuis de nombreuses années que la gestion de la Santé-sécurité au travail (SST) s'effectue par le biais de Systèmes de Management (SMS), la question de la mesure de la performance et du pilotage de ces derniers reste d'actualité. Traditionnellement, la mesure de la performance de ces SMS est fondée sur l'utilisation d'indicateurs de résultats : fréquence et gravité des arrêts de travail et des maladies professionnelles. Ce type d'indicateurs " traditionnels " " a posteriori " présente plusieurs contraintes et limites. Ils sont construits à partir de résultats antérieurs et ne permettent pas, entre autre, de corriger les situations déviantes jamais survenues auparavant. Une transposition du concept de Tableau de Bord " prospectif " appliqué au domaine de la gestion de la SST permet de répondre en partie aux lacunes identifiées avec l'utilisation des seuls indicateurs SST " traditionnels " Un cas pratique de Tableau de Bord " prospectif " en SST appliqué à deux principaux processus de gestion de la Santé-Sécurité (maîtrise des conformités réglementaires et des risques professionnels) est décrit dans le cadre d'une expérimentation conduite avec entreprise du domaine de l'aéronautique.
17
Zheng, Li. "Improving performance measurement of engineering projects : methods to develop indicators." Thesis, Toulouse, INSA, 2018. http://www.theses.fr/2018ISAT0006.
Full textAbstract:
La mesure de la performance est l’une des nombreuses activités de la gestion de projet, elle contribue à assurer le succès du projet. Pour atteindre ce but, les entreprises ont besoin de déterminer un système de mesures de la performance. Ces mesures fournissent au chef de projet l’état de santé du projet et l’aide à évaluer s’il a atteint ou va atteindre ses objectifs. Néanmoins, avec la complexité croissante des projets et la nécessité économique absolue d’atteindre les objectifs, les chefs de projets ne peuvent plus se contenter de superviser les coûts et le planning pour évaluer la performance du projet. Ils ont besoin de considérer par exemple d’autres indicateurs comme la satisfaction des exigences du client, la maturité de la technologie, etc. De plus, ils ont besoin d’avoir une évaluation précise des valeurs de ces indicateurs tout au long du projet et pas uniquement à la fin, pour monitorer au mieux le projet afin qu’il atteigne ses objectifs. Pour satisfaire ces nouveaux besoins, les objectifs de cette thèse sont d’étendre le nombre d’indicateurs génériques et de diversifier le type des indicateurs, ainsi que de proposer une méthode pour concevoir des indicateurs spécifiques à un projet. Pour cela, nous procédons par l’intégration de bonnes pratiques pour la mesure de performance issues de plusieurs domaines de l’ingénierie, et illustrons nos propositions sur des cas pratiques. Ce rapport introduit la notion de performance et caractérise les systèmes de mesure de performance, en mettant notamment en évidence un emploi non cohérent de la terminologie selon les sources. Il identifie plusieurs limitations des systèmes de mesure de performance actuels et souligne notamment le besoin d’étendre le nombre et le type des indicateurs, et de construire des indicateurs de performance spécifiques et pertinents pour chaque projet. Une étude bibliographique sur la mesure de la performance dans les domaines de l’ingénierie, notamment en ingénierie système, montre que la mesure de performance est particulièrement bien développée dans cette dernière discipline, avec une offre de 18 indicateurs génériques avancés permettant une grande proactivité. La thèse propose de ce fait d’adapter ces indicateurs au management de projets, résultant en la définition d’un ensemble d’indicateurs étendu et diversifié pour la mesure de performance. Par ailleurs, l’étude des normes et guides en ingénierie système et logicielle (Practical Software and System Measurement, ISO/IEC 15939) nous amène à identifier d’autres besoins, comme la création dynamique d’indicateurs ad hoc qu’il est nécessaire de définir en cours de projet afin évaluer certains risques spécifiques, et soulève de nouvelles difficultés, comme la collecte et la manipulation des données pour la construction des indicateurs. Pour y répondre, ce rapport propose donc également une méthode guidant la construction dynamique d’indicateurs spécifiques. Celle-ci, illustrée dans le mémoire sur un cas concret de projet, a été validée par un panel d’expertsPerformance measurement is essential to ensure the success of a project. To this goal, companies need to determine a system of performance measures, classically including cost and schedule measures, which provide the project manager with the project health status and help her or him to evaluate the project successes and failures. However, with the increasing complexity of projects and the absolute necessity to reach the project objectives, project managers cannot only rely on such information about cost and schedule to evaluate the project performance; they need to consider, for instance, other indicators such as the satisfaction of customer requirements, the technology maturity, etc. Moreover, they need to have a precise evaluation of these indicators values while the project is in progress, in order to monitor it at best so that it reaches its goals, and not only after the project ends, to only conclude on the project success or failure without any mean to react. Considering these two issues, the objectives of the thesis thus are to extend the number, scope and type of current project performance indicators with a proposal of complementary indicators, and to propose a method for designing project-specific indicators, in order to improve project performance measurement. To define supplementary indicators and elaborate such a method, we proceed by integrating good measurement practices from different engineering disciplines and illustrate our proposal on use cases. The thesis first introduces the notion of performance and characterizes performance measurement systems (PMSs); such systems offer a wide panel of models for organizational performance measurement. Focusing on PMSs, we provide some insights for project performance measurement. More precisely, we identify several issues highlighted in literature, relative to the limitations of current project performance measurement such as the need to balance lagging indicators (to control) with leading indicators (to monitor), and the need to construct performance indicators that are relevant to project-specific information needs. We then focus on project performance measurement and reviews literature in this domain. It highlights the issue of the unbalanced use of leading and lagging indicators. To bring a solution to the issue, we review literature of performance measurement in engineering disciplines, with a focus on systems engineering practices, especially a panel of 18 generic leading indicators that are currently engineered in guidance. A method has been proposed to adapt the set of systems engineering leading indicators to project management, thus resulting in developing the set of indicators to measure project performance. Moreover, focusing on standards and guides on measurement in systems and software engineering led us to identify other issues in project performance measurement, such as the difficulties to define indicators dynamically for a project, and how to collect and combine data in order to construct these indicators. We finally consider the methodological difficulties about designing relevant performance indicators. More precisely, we identify 3 issues: different opinions among researchers about the sources from where the indicators will be derived; the problem in relation to the transformation from data to indicators; and the association of data collection, analysis and report with project management processes. To solve these issues, we analyze good practices from the Practical Software and Systems Measurement, the ISO/IEC 15939 norm and the Project Management Body of Knowledge that proved to be able to address the identified issues respectively. This work results in a method integrating these practices to address the 3 identified issues in project performance measurement. The method is illustrated on a real project context. Evaluation of the method has been conducted in workshop of project managers, which confirmed the interest for the proposal
18
Okonkwo, C. T. "The geology and geochemistry of the metasedimentary rocks of the Loch Laggan - Upper Strathspey area, Inverness-shire." Thesis, Keele University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355609.
Full text
19
Laggies, Sandra [Verfasser], and Gerhard [Akademischer Betreuer] Gross. "Ein eingeschränktes therapeutisches Potential mesenchymaler Stammzellen für die Kollagen-induzierte Arthritis in DBA/1-Mäusen / Sandra Laggies ; Betreuer: Gerhard Gross." Braunschweig : Technische Universität Braunschweig, 2012. http://d-nb.info/1175824518/34.
Full text
20
Laggies, Sandra Michaela [Verfasser], and Gerhard [Akademischer Betreuer] Gross. "Ein eingeschränktes therapeutisches Potential mesenchymaler Stammzellen für die Kollagen-induzierte Arthritis in DBA/1-Mäusen / Sandra Laggies ; Betreuer: Gerhard Gross." Braunschweig : Technische Universität Braunschweig, 2012. http://nbn-resolving.de/urn:nbn:de:gbv:084-12050211488.
Full text
21
Chen, Liang-Jhang, and 陳良彰. "Numerical Analysis for the Thermal Lagging Behavior." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/47139675794755574019.
Full textAbstract:
碩士國立成功大學
工程科學系碩博士班
95
Under the micro-scale condition of space and time, this paper is to study the time-lagging effect caused by the thermal lagging behavior and its heat transfer effects in three mathematical models, which are the diffusion, CV wave and dual-phase-lag models. The first one is the Fourier’s heat conduction equation and the others are the hyperbolic equations. The CV wave model is more than the diffusion one by one term of second order time derivative and the dual-phase-lag model is more than the CV one by one term of second order time-and-space mixed derivative. These two extra terms make the numerical calculation oscillate and diverge easily. In the one-dimensional simulation analysis, two physical models are applied. In the first one, the high and low temperature boundaries are used and the model is expressed in the dimensionless form. In the second one, the heat-insulated boundaries and laser heat source are utilized. Several numerical methods are used to simulate these two physical models and the computing results are compared with the exact ones. From the analysis results, it can be found that the implicit method (centered difference for the derivatives of space and time) is the best one for the first physical model without any stability problems. For the second model, the explicit method is the best one, but it needs to take the stability criterion into account.
22
Huang, Chong-Ming, and 黃崇銘. "The leading and lagging relationship between CB return and stock return." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/qn4t9k.
Full textAbstract:
碩士國立中山大學
財務管理學系研究所
96
Due to the characteristics of convertible bond, the issuing volumes are smaller than stocks and the investors are mostly institutional investors. Therefore, the turnover and the market liquidity of convertible bond are lower than those of stock market. The past literature indicate that the reaction of corporate bond to the fundamental information falls behind the stock, therefore, the price change of corporate bond always lag behind that of stock market. Moreover, the extra right of convertible bond compare to corporate bond is the convertible option in exchange for stocks, that also causes the relation between the stocks and the convertible is much closer than the normal corporate bond. The motivation of this study is to take advantage of the co-movement relation between these two markets to discover the profit opportunities of investment strategy. As a result, the purpose of this study is to investigate the prediction of the convertible bond and the reaction of the market information. Firstly, I try to verify momentum effect or overreaction effect in convertible bond is significant. Second, I apply the VAR model and Granger model to analyze the return relationship between convertible bonds and stocks, and to formulate our strategies by predicting the return of convertible bond from the lagged return of stocks. At the end, I analyze the performance of strategy in order to discover the best timing of buying convertible bonds for investors. Our empirical study exhibits there has no momentum effect in Taiwan convertible bonds market. Conversely, we discover the presence of overreaction effect but it is insignificant. Moreover, it’s effective to predict the return of convertible bond by using the stocks return, otherwise it’s not. Finally, the strategy of using the stock return in predicting the return of convertible bond can earn abnormal return without considering the transaction cost. On the contrary, the performance of using the return of convertible bond in predicting the stock return is insignificant. Our results demonstrate that we can refer to the past literature about “the reaction of corporate bond to the fundamental information of companies falls behind the stock” to invest in convertible bond profitably. In conclusion, investors can follow our empirical framework and result to forecast the price trend of the convertible bond by referring the stock price.
23
Arora, Rashmi Umesh. "Uttar Pradesh - lagging state of India: economic development and role of banks." 2007. http://hdl.handle.net/2292/2386.
Full textAbstract:
The present study challenges the negative and static stance of the recent literature on Uttar Pradesh, the most populous state of India, and espouses a balanced and moderate approach. The existing literature focuses only on human development and ignores the underlying social, political and economic changes taking place in the state. It ignores the decline in credit to the state. The present study synthesises and amalgamates various streams of literature on the state to fill the gap. It uses bank credit and its role in UP’s economic development as a tool to explore the changes and structural and regional shifts in the state. It examines bank credit to various regions, districts, occupations, rural and urban populations, large and small borrowers and gender in UP. This study explores credit in a multi-dimensional framework as a route to growth, development, inequality, globalisation, urbanisation, and empowerment. The study further explores the relationship between bank credit and the state’s human development. As a critique of the existing literature, the study examines whether UP is really lagging behind other states of India. Through a twin indicator approach, broadly grouped into income and non-income, the study shows that the state does lag on income front. The non-income indicators analysis, however, shows that a number of other states including high-income states are lagging. The study eschews the watertight categorisation of east and west UP as pursued in the existing literature, and adopts a broader regional classification. This showed that, although gradual, change has occurred in UP. The overall findings of the study suggest that structural and non-structural constraints characterise the development of the state. The multiple roles of credit have generated growth, helped in poverty reduction, but also influenced regional inequality and rural-urban inequalities, and widened the gap between small and large borrowers in the state. The empowerment of women through credit from commercial banks remains a distant goal as women receive less than 20 per cent of the total credit. Another significant finding of the study is that the income and non-income factors are strongly correlated, for instance, the strong negative relationship between income and the Human Poverty Index. The study, therefore, underlines the need for increased economic growth to achieve better economic and human development outcomes.
24
Nel, E. L., C. M. Rogerson, and L. Marais. "Restructuring manufacturing in South Africa's lagging regions : the case of the Free State." 2006. http://eprints.ru.ac.za/356/1/restructuring.pdf.
Full textAbstract:
The manufacturing economy of the Free State reflects both historical dependence on locally available raw materials and high-levels of state intervention, in terms of support for import substitution and Homeland development. In the contemporary era, deindustrialization, the uncertain future of the clothing / textile industries and limited growth over the last ten years, suggests that, in terms of manufacturing, the Free State is a 'lagging' region. While there has been significant expansion in the number of small firms, this is not matched by employment growth and does not compensate for the loss of many large firms and economic downscaling in the Goldfields. Key sectors such as petro-chemicals and gold jewellery present certain opportunities for future growth.
25
Randolph, Robert Winston. "A task based exposure assessment of airborne asbestos fibres during boiler de-lagging." Thesis, 2009. http://hdl.handle.net/10539/6063.
Full textAbstract:
ABSTRACT
Asbestos has been extensively used to insulate boilers and associated heated pipe work
throughout the world. Managing human health risks posed by asbestos during the
removal of lagging poses many challenges. For this reason, acquiring a better
understanding of factors that lead work tasks to produce high airborne fibre
concentrations is important for the development of improved control methods.
Aim: The aim of this study was to link observed work tasks and work practices with
measured airborne concentrations of fibres in order to identify those factors contributing
to high airborne concentrations generated during boiler de-lagging. The investigation was
based on a study of two employees working on a boiler de-lagging contract lasting
twenty-one days and resulting in a total of 79 measurements of airborne asbestos fibres.
The primary form of asbestos dust control for the duration of the contract was the
application of non-amended water.
Objectives: To definitively identify the presence and type of asbestos lagging as well as
quantify airborne fibre concentrations for two work tasks i.e. Stripping (removing
lagging) and Bagging (placing removed lagging into bags as well as cleaning spills), in
order to demonstrate how they may influence airborne fibre concentrations.
Methodology: The type of asbestos was confirmed by Scanning Electron Microscopy.
Phase Contrast Microscopy (PCM) was selected as the primary measure of airborne
asbestos fibres. A Work Practice Checklist was developed to link observed daily Work
Tasks and Work Practices with the concurrent airborne fibre concentrations. The
geometric mean was a useful measure of central tendency for the data since it was highly
skewed to the right (positively skewed). However, for public health purposes the
arithmetic mean was also considered because it provides some idea of health risk where
the human respiratory system is assumed to accumulate fibres linearly with
concentration.
Results: Bulk sample analysis confirmed the presence of both chrysotile and amosite
asbestos lagging. Work Practices such as Wetting, Stripping and Bagging asbestos, were
undertaken in a relatively uncontrolled manner during the first three days of the project
resulting in mean airborne fibre concentrations of 1.171 f/ml for the Stripper, ranging
from 0.612 to 1.236 f/ml and 0.315 f/ml for the Bagger, ranging from 0.107 to 0.631f/ml.
These means were 4.5 times and 2.3 times respectively, greater than the means calculated
for the entire project. The overall mean fibre concentration was approximately five times
greater for personal samples, 0.198 f/ml (± 1.647) than for the concurrent static samples,
0.039 f/ml (± 0.129).
The analysis of log transformed data revealed several strong tendencies for airborne fibre
concentrations when related to Work Tasks and Work Practices. The difference between
stripping asbestos in small manageable as opposed to larger unmanageable pieces was
highly significant (p < 0.001). Smaller manageable pieces resulted in much lowerconcentrations. The manner with which asbestos was bagged was also highly significant
(p < 0.001). Bagging in an uncontrolled manner resulted in much higher airborne
concentrations. Surprisingly, the degree of wetting was not as important as expected:
working dry did not generate significantly more fibres than working with saturated
insulation but did generate significantly more fibres (p < 0.005) than working with
partially wet insulation (which lead to the highest concentrations). A limitation to
interpreting the Wetting work practice was the low number of samples taken within the
dry category (n = 5).
The difference in mean sample concentrations between personal and static samples for
this study demonstrates the importance of spatial and temporal proximity as a
determinant for airborne fibre concentrations. It also showed clear associations between
what can be described as rushed, reckless Work Practices, and the resulting high levels of
airborne fibre concentrations (exceeding the OEL). Within the context of this project,
these findings demonstrate the utmost importance of providing the appropriate training
and supervision of employees, not only for protecting themselves against airborne
asbestos fibres, but for removing asbestos in manner that results in the generation of the
least amount of airborne fibres possible
26
Yang, Chiao-Kai, and 楊喬凱. "Constructing a Default Rate Forecasting Model with Leading and Lagging Effects of Economic Indicators." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/10221073957568281917.
Full textAbstract:
碩士國立交通大學
工業工程與管理學系
100
In recent years, facing the world financial crisis, Taiwan's banks are also affected. Banks face many default corporate borrowers. Therefore, accurately forecasting the default rate of banks and financial institutions will reduce financial risk. The existing literature has proposed using economic indicators to construct the default rate forecasting model. However, some economic indicators have leading or lagging effect, and they will affect the accuracy of the forecasting model of default rate. Therefore, the main purpose of this study is to consider the leading and lagging effects of the economic indicators, using correlation analysis and Vector Autoregression(VAR) method to analyze the leading and lagging effects of economic indicators, and then using the stepwise regression, and Group method of the Data Handling (GMDH) to construct the default rate forecasting model. Finally, this study utilizes a real case to verify that the proposed method has higher accuracy rate than that of a prediction model without not considering the leading and lagging effect of economic indicators .
27
Wang, Mengtian. "Normalization of Process Safety Metrics." Thesis, 2012. http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11490.
Full textAbstract:
This study is aimed at exploring new process safety metrics for measuring the process safety performance in processing industries. Following a series of catastrophic incidents such as the Bhopal chemical tragedy (1984) and Phillips 66 explosion (1989), process safety became a more important subject than ever. These incidents triggered the development and promulgation of the Process Safety Management (PSM) standard in 1992. While PSM enables management to optimize their process safety programs and organizational risks, there is an emerging need to evaluate the process safety implementation across an organization through measurements. Thus, the process safety metric is applied as a powerful tool that measures safety activities, status, and performance within PSM.
In this study, process safety lagging metrics were introduced to describe the contribution of process related parameters in determining the safety performance of an organization. Lagging metrics take process safety incidents as the numerator and divide it by different process-related denominators. Currently a process lagging metric (uses work hours as denominator) introduced by the Center for Chemical Process Safety (CCPS) has been used to evaluate the safety performance in processing industries. However, this lagging metric doesn't include enough process safety information. Therefore, modified denominators are proposed in this study and compared with the existing time-based denominator to validate the effectiveness and applicability of the new metrics. Each proposed metric was validated using available industry data. Statistical unitization method has converted incident rates of different ranges for the convenience of comparison. Trend line analysis was the key indication for determining the appropriateness of new metrics. Results showed that some proposed process-related metrics have the potential as alternatives, along with the time-based metric, to evaluate process safety performance within organizations.
28
"A comparative analysis of the regulation of demutualised stock exchanges : is South Africa lagging behind." Thesis, 2015. http://hdl.handle.net/10210/14018.
Full text
29
WANG, GUO-YI, and 王國易. "Implementation of a Hybrid Phase-Shift Full-Bridge DC-DC Converter with ZVZCS on Lagging Leg." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/xhvd6n.
Full textAbstract:
碩士國立虎尾科技大學
電機工程系碩士班
107
The traditional phase-shifted full-bridge converter (PSFB) uses phase-shift control to achieve zero-voltage switching (ZVS) of the switch. It has been widely used in the high power conversion applications due to its high stability and simple structure. PSFB converter has following disadvantages, such as: the limited ZVS range of the lagging leg, secondary side ringing phenomenon, circulating current loss, duty cycle loss and other defects. The converter cannot be operated efficiently at light load condition. To overcome these shortcomings, this thesis proposes a hybrid phase-shift full-bridge converter which uses a shared switch to combine a PSFB converter with a half-bridge (HB) LLC resonant converter to ensure the switches in the lagging leg operating at fully ZVS condition. The output of the PSFB converter and the HB LLC resonant converter are connected in series and the converter output voltage can be adjusted by adjusting the phase shift angle. In addition, an auxiliary resonant circuit is used to the secondary side of the full-bridge converter. The advantages are summarized as follows: (1) During freewheeling period, the primary current is reset to zero, reducing the circulating current loss and the switches in the lagging leg can achieve zero-current switching (ZCS); (2) The secondary side ringing phenomenon is improved by the clamping of the resonant circuit; (3) The efficiency of energy transfer can be improved by the freewheeling period circuit loop. The proposed hybrid phase-shift full-bridge converter operation principle will be analyzed to design suitable circuit parameters. Finally, a 1000W hybrid phase-shift full-bridge converter experimental prototype was developed to verify the principle of operation and parameter design. The experimental results show that the efficiency can be above 90% when the output power range from 200 to 1000W. The maximum efficiency can achieve 96.24% at 720W condition.
30
Ming-Chun, Ou, and 歐明俊. "The Effectiveness of Shadowing and Lagging Training-Focus on Chinese-speaking Japanese Language Learners' Pronunciation Instruction-." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/34075910064208804162.
Full textAbstract:
碩士東吳大學
日本語文學系
102
This paper aims to provide a more effective Japanese teaching method to solve the difficulties of second-language teaching and learning of Japanese pronunciation instruction for teacher and student. In this paper, the chapter 1 to chapter 3 shows that from view of cognitive and brain science, how shadowing and lagging be used to Japanese pronunciation instruction, and bring some success. In chapter 4, it is showed the experimental design and related summary to verify my assumption: it will take a good influence to Japanese pronunciation instruction by using of shadowing and lagging. About analysis of experimental results, it could be divided into qualitative analysis and quantitative analysis. In chapter 5, the result of qualitative analysis shows the differences between the experimental and control groups by statistical methods ANOVA. In chapter 6, the quantitative study uses speech analysis software “praat” to show the spectrogram of experimental and control groups, and to observe the longitudinal changing between groups. The results show students in the experimental group in which each user accepted a six-month exercise of shadowing and lagging, took significant improvements in Japanese pronunciation instruction. It means that shadowing and lagging are complementary to each other, and bring better results of second-language learning.
31
Arora, Rashmi, and Kifle Asfaw Wondemu. "Do public sector banks promote regional growth? Evidence from an emerging economy." 2018. http://hdl.handle.net/10454/15140.
Full textAbstract:
YesA large literature exists on the relationship between financial development and economic growth. The role of government and public banks in building this relationship has however, remained contentious. In this study in a sub-national level of analysis in the context of large emerging economy, India we raise the question what is the relative impact of public banks in economic growth in the lagging regions vis-à-vis leading regions? Do they matter more than the private and foreign banks? To address these problems, we apply dynamic GMM panel estimator on an unbalanced panel dataset drawn from 25 Indian states covering period 1996/97 to 2008/09. Although our study is in the Indian context, it is relevant for developing countries for mainly two reasons: government ownership of banks has been widely prevalent in developing countries and in many large countries in a federation set-up inter-state differences may exist with multiple ownership of the financial sector.
The full-text of this article will be released for public view at the end of the publisher embargo on 26 Mar 2020.
32
Li, Tai-Ying, and 李泰穎. "Using PySpark and Distributed Computing to Solve the Lagging Problem of Stored Procedure with Standalone and Massive Computing." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/4pcvuw.
Full textAbstract:
碩士臺北市立大學
資訊科學系碩士在職專班
105
Due to the basic features of ACID theory and Script program, the Relational Database Management System and the Structured Query Language limit the Stored Procedure which can only run in the Relational Database Management System environment with standalone mode for data processing. In terms of time, even calling or using any computing resources of other servers or databases, it still has to wait for the previous transaction to be completed before processing the next transaction. However, in the wake of data is getting more and more extensive in quality, quantity, type and demand, especially when the Stored Procedures are required to cope with a large amount of data that consumes a lot of CPU and memory work such as reporting calculations, the resulted lagging problem has affected the normal function or operation of other applications or systems owned by other databases within the same database server. Even if performing hardware and software upgrades, index using, table partition, table compression, off-peak time operation settings or other database performance tuning actions, over the long term accumulating of data, the performance of the improvement is also quite limited. All that the Spark open source cluster framework is living for fast running and genericization purposes. Based on the features of the Spark packs, such as work scheduling, memory management, fault tolerance and file system, are providing the key technologies of the best solution to integrate the advantages of the Relational Database and the Big Data Architecture. This study, using the PySpark library and the Distributed Computing, put forward specific and effectively feasible solutions to solve the encountered lagging problem of the Stored Procedure with standalone and massive computing.
33
Lin, Ye-Chen, and 林曄辰. "The analytical model for drawdown due to constant-rate pumping test in a leaky aquifer: considering lagging effect." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/aa3x75.
Full textAbstract:
博士國立交通大學
環境工程系所
106
This study proposes a generalized Darcy’s law with considering phase lags in both the water flux and drawdown gradient to develop a lagging flow model for describing drawdown induced by constant-rate pumping (CRP) in a leaky confined aquifer. The present model has a mathematical formulation similar to the dual-porosity model. The Laplace-domain solution of the model with the effect of wellbore storage is derived by the Laplace transform method. The time-domain solution for the case of neglecting the wellbore storage and well radius is developed by the use of Laplace transform and Weber transform. The results of sensitivity analysis based on the solution indicate that the drawdown is very sensitive to the change in each of the transmissivity and storativity. Also, a study for the lagging effect on the drawdown indicates that its influence is significant associated with the lag times. The present solution is also employed to analyze a data set taken from a CRP test conducted in a fractured aquifer in South Dakota, USA. The results show the prediction of this new solution with considering the phase lags has very good fit to the field data, especially at early pumping time. In addition, the phase lags seem to have a scale effect as indicated in the results. In other words, the lagging behavior is positively correlated with the observed distance in the Madison aquifer.
34
Jian-JyunChiu and 邱建鈞. "Thermal Lagging Behavior With The Effect Of Latent Heat By Using Hybird Laplace Transfer And Curve-Fitting Methods." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/85077406971392249828.
Full textAbstract:
碩士國立成功大學
工程科學系碩博士班
101
Technology development advances rapidly day by day. To solve micro-scale heat transfer problems encountered in engineering applications is necessarily based on the macroscopic Fourier heat transfer phenomena. With the basis, the microscopic non-Fourier heat transfer problems would be analyzed effectively and therefore the actual heat transfer problems in engineering could be studied. The main purpose of this paper is using the hybrid Laplace transform method with curve fitting techniques to analyze the non-Fourier heat transfer problems. If the heat transfer process involves phase-change, the temperature recovery method is applied to handle the effect of latent-heat release. ∂θ(δ,0)/∂β is the main reason causing the numerical oscillating results in solving CV wave models by using the hybrid Laplace transform method and the time marching scheme. In the study, the oscillating problem is solved by developing a curve-fitting formula to calculate ∂θ(δ,0)/∂β, which is derived from the modified time-marching method of the previous works. The developed method is called the curve-fitting time marching scheme. Afterwards, the CV model with the release of latent heat could be analyzed numerically. ∂^2 θ(δ,0)/∂δ^2 is the primary cause leading to the unstable numerical results in solving dual-phase models. Similarly, a curve-fitting formula is obtained to calculate ∂^2 θ(δ,0)/∂δ^2, which could help to solve the dual-phase model effectively. Subsequently, the dual-phase model with phase change could be investigated numerically.
35
Intania, Rifa, and Rifa Intania. "Optimized System Dynamics Model of A Local Fashion Brand in Indonesia by Combining Leading and Lagging Indicators: An Initial Study." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/5598q6.
Full textAbstract:
碩士國立臺灣科技大學
工業管理系
106
Nowadays fierce competition pushes any company to make decision faster and more accurate since any market changes can be more unpredictable. There then rises need to realize leading indicators of company performance to quickly evaluate the ongoing or planned strategies in a company; since it will give the managers to manage some decisions more accurately, fit, and reliable to the actual competition condition. This study proposes two new metrics as the leading indicators of company performance, namely advertising ‘reach’ and endorsement ‘likes’; and utilize best combination of marketing-mix elements to generate the highest profit for the company, with the profit being the lagging indicator of company performance. By using system dynamic approach and genetic algorithm to generate the highest profit of the company, this study will capture and utilize leading and lagging indicators that could be used to evaluate the performance of a company. This study uses the data from a small fashion company in Bandung, Indonesia. The result of the simulation that the higher the effectiveness of advertising and endorsement programs, the more they benefit the company in terms of Sales Volume and Number of Customers; while the higher the number of ‘reach’ and ‘likes’ will result in the bigger number of people aware of the existence of the brand.
36
Chen, Ko-Wen, and 陳科文. "Selection of Underlying Index for Stock Sub-index Future and Discussion of Leading-Lagging Correlation of Stock Sub-index in Taiwan." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/99882181183599953578.
Full text
37
Lin, Chen-Chun, and 林貞君. "A Study of Leading-Lagging Relationship between Propert y and Iron&Steel Industries: Evidence from Stock Returns and Operating Performance." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/81220907429036622557.
Full textAbstract:
碩士國立成功大學
高階管理碩士在職專班
94
This article investigates the leading-lagging relationship between the property and iron & steel industries. This study tries to predict the trend of lagging property industry by examining that of leading iron & steel industry for purpose of the improvement of management decision as well as investment related analysis. Empirically, we use value-weighted stock index returns and the financial ratio to test the between-industry relationship and also expect that the relationship between these industries we concern would change with specific macroeconomic index. Our results show that the property industry index return is the leading indicator of the iron & steel industry consistent with the arguments the prosperous property industry could subsequently promote the iron & steel industry boom. When operating performance used, we find the similar result that the property industry performance is positively correlated with that of lagged iron & steel industry. Besides, the results indicate that the leading-lagging relationships between the two industries discussed above would decline with some macroeconomic indicators.
38
Kennedy, HEATHER. "An Investigation of Neutral Hydrogen in Three Edge-on Spiral Galaxies." Thesis, 2009. http://hdl.handle.net/1974/5134.
Full textAbstract:
We present the results of a new and high sensitivity study of the neutral hydrogen (HI) gas in three early type edge-on spiral galaxies, NGC 4157, NGC 3600 and NGC 2683. All three galaxies reveal HI disks that extend nearly or more than twice the length of the optical disk, which ubiquitously reveal asymmetries and warps. We model each galaxy using a three-dimensional kinematic model to derive the empirical parameters of the density distribution functions and rotation curves. A Gaussian function is unanimously found to best represent the density distribution in the plane of the galaxies. We also find that there is in fact a thick HI disk extending into the halo of two of three of these galaxies with scale heights on kpc. scales. This gas suggests the existence of two separate widespread components: a thin, high intensity disk component, normally rotating, and a vast, low intensity halo component, rotating at slower velocities with respect to the disk. This vertical velocity gradient is perhaps our most significant finding in addition to the discovery of the two new HI halos. We also find an unevenly distributed small-scale component of the gas in the form of shell-like and filamentary structures that extend from the disk into the halo. In all three systems we find unique kinematic and structural peculiarities including an HI disk extending four times the optical disk, a declining rotation curve, a companion, expanding bubbles, disk warps, etc. Several physical parameters are derived such as neutral hydrogen and dynamic masses, systemic velocities, HI radii, HI halo masses, etc. All of our findings are investigated and discussed in depth for each of the three galaxies.Thesis (Master, Physics, Engineering Physics and Astronomy) -- Queen's University, 2009-09-03 19:47:31.786
39
Ononye, Onyekachi Ebelechukwu. "Defining the Role of Lysine Acetylation in Regulating the Fidelity of DNA Synthesis." Thesis, 2020. http://hdl.handle.net/1805/24762.
Full textAbstract:
Indiana University-Purdue University Indianapolis (IUPUI)Accurate DNA replication is vital for maintaining genomic stability. Consequently, the machinery required to drive this process is designed to ensure the meticulous maintenance of information. However, random misincorporation of errors reduce the fidelity of the DNA and lead to pre-mature aging and age-related disorders such as cancer and neurodegenerative diseases. Some of the incorporated errors are the result of the error prone DNA polymerase alpha (Pol α), which initiates synthesis on both the leading and lagging strand. Lagging strand synthesis acquires an increased number of polymerase α tracks because of the number of Okazaki fragments synthesized per round of the cell cycle (~50 million in mammalian cells). The accumulation of these errors invariably reduces the fidelity of the genome. Previous work has shown that these pol α tracks can be removed by two redundant pathways referred to as the short and long flap pathway. The long flap pathway utilizes a complex network of proteins to remove more of the misincorporated nucleotides than the short flap pathway which mediates the removal of shorter flaps. Lysine acetylation has been reported to modulate the function of the nucleases implicated in flap processing. The cleavage activity of the long flap pathway nuclease, Dna2, is stimulated by lysine acetylation while conversely lysine acetylation of the short flap pathway nuclease, FEN1, inhibits its activity. The major protein players implicated during Okazaki fragment processing (OFP) are known, however, the choice of the processing pathway and its regulation by lysine acetylation of its main players is yet unknown. This dissertation identifies three main findings: 1) Saccharomyces cerevisiae helicase, petite integration frequency (Pif1) is lysine acetylated by Esa1 and deacetylated by Rpd3 regulating its viability and biochemical properties including helicase, binding and ATPase activity ii) the single stranded DNA binding protein, human replication protein A (RPA) is modified by p300 and this modification stimulates its primary binding function and iii) lysine acetylated human RPA directs OFP towards the long flap pathway even for a subset of short flaps.
40
Assunção, Eduardo Alexandre Cardoso de. "Indicadores de desempenho de segurança no contexto organizacional." Master's thesis, 2020. http://hdl.handle.net/1822/71175.
Full textAbstract:
Dissertação de mestrado integrado em PsicologiaA literatura recente tem vindo a desafiar à criação e validação de instrumentos de medida claros, estandardizados e universais para medidas de desempenho e clima de segurança. O presente projeto teve como principal objetivo contribuir para o estudo do clima de segurança organizacional e de leading e lagging indicators, no contexto português, através da adaptação e criação de ferramentas de investigação que sejam fiáveis e válidas. Participaram 267 trabalhadores operários da indústria transformadora e construção civil, setores mais afetados por acidentes mortais em Portugal. De um modo geral, os resultados ao nível das propriedades psicométricas dos instrumentos utilizados foram consistentes com as versões originais e a análise da relação entre as diferentes variáveis consistente com a literatura recente na área.
The recent literature has been asking for the creation and validation of clear, standardized and universal measure instruments of safety climate and performance. The present project had as the main objective to contribute to the study of safety climate, leading and lagging indicators, on the Portuguese context, trough the adaptation and creation of valid and reliable research tools. The sample was composed by 267 blue-collar workers from construction and manufacturing industry (most punished sectors by mortal accidents in Portugal). In general, the results in terms of the psychometric properties of the instruments used were consistent with the original versions and the analysis of the relationship between the different variables consistent with recent literature in the area.
41
NOVÁKOVÁ, Ilona. "Devizová expozice a devizové riziko." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-156528.
Full textAbstract:
Thesis "Foreign exchange exposure and currency risk" deals with managing foreign currency exposure and foreign exchange risks when doing business in The Czech Republic. It defines foreign exchange risk, different types of foreign exchange exposures and the possibility of its ensuring, as well as internal and external methods of reducing foreign exchange exposure and foreign exchange risk. The practical part is devoted to a particular solution, respectively to the management of foreign exchange exposure and foreign currency risk in ABC, s.r.o. company.
42
Prem, Katherine. "Risk Measures Constituting Risk Metrics for Decision Making in the Chemical Process Industry." Thesis, 2010. http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8678.
Full textAbstract:
The occurrence of catastrophic incidents in the process industry leave a marked legacy of resulting in staggering economic and societal losses incurred by the company, the government and the society. The work described herein is a novel approach proposed to help predict and mitigate potential catastrophes from occurring and for understanding the stakes at risk for better risk informed decision making.
The methodology includes societal impact as risk measures along with tangible asset damage monetization. Predicting incidents as leading metrics is pivotal to improving plant processes and, for individual and societal safety in the vicinity of the plant (portfolio). From this study it can be concluded that the comprehensive judgments of all the risks and losses should entail the analysis of the overall results of all possible incident scenarios. Value-at-Risk (VaR) is most suitable as an overall measure for many scenarios and for large number of portfolio assets. FN-curves and F$-curves can be correlated and this is very beneficial for understanding the trends of historical incidents in the U.S. chemical process industry.
Analyzing historical databases can provide valuable information on the incident occurrences and their consequences as lagging metrics (or lagging indicators) for the mitigation of the portfolio risks. From this study it can be concluded that there is a strong statistical relationship between the different consequence tiers of the safety pyramid and Heinrich‘s safety pyramid is comparable to data mined from the HSEES database. Furthermore, any chemical plant operation is robust only when a strategic balance is struck between optimal plant operations and, maintaining health, safety and sustaining environment.
The balance emerges from choosing the best option amidst several conflicting parameters. Strategies for normative decision making should be utilized for making choices under uncertainty. Hence, decision theory is utilized here for laying the framework for choice making of optimum portfolio option among several competing portfolios. For understanding the strategic interactions of the different contributing representative sets that play a key role in determining the most preferred action for optimum production and safety, the concepts of game theory are utilized and framework has been provided as novel application to chemical process industry.
43
Antwi, Albert. "Profit risk models for South African banking sector." Diss., 2016. http://hdl.handle.net/11602/767.
Full text
44
Πέτρου, Αναστασία. "Οικονομικά θέματα ανάπτυξης του αγροτικού τουρισμού σε μειονεκτικές περιοχές." 2005. http://nemertes.lis.upatras.gr/jspui/handle/10889/286.
Full textAbstract:
Εξετάζεται η ζήτηση για αγροτικό τουρισμό με τη χρήση ενός οικονομικού-οικονομετρικού μοντέλου. Αναγνωρίζεται η ιδιαίτερη φύση του αγροτικού τουρισμού σαν ένα ετερογενές προϊόν-υπηρεσία, ενώ παράλληλα δίνεται έμφαση στο ρόλο της πληροφόρησης των καταναλωτών και στην πόιότητα της ταξιδιωτικής εμπειρίας. Επίσης, αναλύεται η σημασία των τοπικών προϊόντων διατροφής, ως μέρος της ταξιδιωτικής εμπειρίας σε μια περιοχή. Με βάση τα αποτελέσματα προτείνονται βασικοί άξονες για την ανάπτυξη του αγροτικού τουρισμού, ως βασικού μοχλού για την τοπική και περιφερειακή ανάπτυξη σε μειονεκτικές περιοχές.The demand for rural tourism is analysed using a proper economic and econometric model. Rural tourism is conceptualised as a heterogeneous product-service, while at the same time analysis focus on the role of consumers.
45
BLECHOVÁ, Pavlína. "Devizová expozice a devizové riziko u výrobního podniku." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-188164.
Full textAbstract:
Graduation theses named "Exchange exposition and exchange risk of production company" is focused on problems of management of exchange position and exchange risk in production company, which is under legislative The Czech Republic. Firstly the theses define basic terms, types of exchange operations, kinds of exchange exposition, internal and external methods of assuring of exchange risk. The practical part is focused on concrete solution of exchange position and ensuring exchange risk in the company Alfa CZ spol. s r. o..
46
Vázquez, de Castro Diez Cayetana. "Causes and consequences of chromosome segregation errors in the mouse preimplantation embryo." Thesis, 2018. http://hdl.handle.net/1866/21198.
Full textAbstract:
La division cellulaire est un processus biologique universel nécessaire à la reproduction, au développement, à la survie cellulaire ainsi qu’à la réparation des tissus. Une ségrégation chromosomique exacte pendant la mitose est essentielle pour une répartition égale des chromosomes répliqués entre les cellules filles. Des erreurs dans la ségrégation des chromosomes mènent à une condition appelée aneuploïdie, définie par un nombre inadéquat de chromosomes dans une cellule. L’aneuploïdie est associée à une altération de la santé cellulaire, la tumorigénèse, des malformations congénitales et l'infertilité. Contre toute attente, les embryons préimplantatoires de mammifères, dont les humains, consistent souvent en un mélange de cellules euploïdes et de cellules aneuploïdes. Ce mosaïcisme est inexorablement causé par des erreurs dans la ségrégation des chromosomes au cours des divisions mitotiques suivant la fécondation et est associé à un potentiel de développement réduit lors des traitements de fertilité. Malgré sa découverte il y a 25 ans, les mécanismes qui sous-tendent l’apparition de l'aneuploïdie mosaïque dans les embryons préimplantatoires sont toujours méconnus.
Pour explorer les causes et les conséquences des erreurs de ségrégation chromosomique, des approches d'imagerie de fine pointe ont été utilisées sur des embryons préimplantatoires murins. L'analyse de la dynamique de la ségrégation des chromosomes via l’imagerie de cellules vivantes a permis d’identifier les chromosomes retardataires, lors de l’anaphase, comme la forme la plus répandue des erreurs de ségrégation. Ces chromosomes retardataires entraînent fréquemment une encapsulation de chromosome unique dans une structure appelée micronoyau. D'autres expériences d'imagerie par immunofluorescence sur des cellules vivantes ou fixées ont révélé que les chromosomes des micronoyaux subissent des dommages importants à l'ADN et sont mal répartis de manière récurrente lors des divisions cellulaires subséquentes dans la phase préimplantatoire. D’autres approches ont aussi permis d’examiner l'efficacité du mécanisme de contrôle de l’assemblage du fuseau mitotique, (SAC pour Spindle Assembly Checkpoint). Les résultats obtenus attestent que le SAC fonctionne, cependant la signalisation liée au SAC n’est pas efficace et ne permet pas de différer l'anaphase, malgré la présence de chromosomes retardataires et ce indépendamment de la taille des cellules. Les résultats présentés révèlent aussi qu’une inhibition partielle d’une cible du SAC, le complexe de promotion de l'anaphase (APC/C), cause une mitose prolongée et une réduction des erreurs de ségrégation. En outre, les études présentées démontrent que la fonction déficiente du SAC pendant le développement préimplantatoire est la cause principale d’une forte incidence de chromosomes retardataires qui entraînent une mauvaise ségrégation chromosomique répétée et qui causent une aneuploïdie mosaïque dans l’embryon. De plus, ce travail fournit la preuve que la modulation pharmacologique de la signalisation SAC-APC/C permet d’éviter les erreurs de ségrégation des chromosomes dans les embryons précoces.
En conclusion, ces résultats apportent de nouvelles perspectives sur les causes et la nature des erreurs de ségrégation chromosomique dans les embryons. De plus, ce travail apporte de nouvelles explications mécanistiques sur l'apparition du mosaïcisme dans les embryons ce qui aura des implications importantes dans la détection et la prévention thérapeutique potentielle de l'aneuploïdie mosaïque dans les embryons préimplantatoires.Cell division is a universal biological process necessary for reproduction, development, cell survival and the maintenance and repair of tissues. Accurate chromosome segregation during mitosis is essential to ensure replicated chromosomes are partitioned equally into daughter cells. Errors in chromosome segregation often result in cells with abnormal numbers of chromosomes, a condition termed aneuploidy, which is associated with impaired cellular health, tumorigenesis, congenital defects and infertility. Counterintuitively, preimplantation embryos from many mammalian species, including humans, often consist of a mixture euploid and aneuploid cells. Such mosaic aneuploidy in embryos is inexorably caused by errors in chromosome segregation during mitotic divisions following fertilization and has been associated with reduced developmental potential in fertility treatments. However, ever since its discovery 25 years ago, how and why mosaic aneuploidy arises in the preimplantation embryo has remained elusive. To explore the causes and consequences of embryonic chromosome segregation errors, advanced imaging approaches were employed in the mouse preimplantation embryo. Live cell imaging analysis of chromosome segregation dynamics identified lagging anaphase chromosomes as the most prevalent form of chromosome mis-segregation in embryos. Lagging chromosomes frequently result in the encapsulation of single chromosomes into micronuclei, which occur in embryos in vitro and in vivo. Further live imaging and immunofluorescence experiments revealed chromosomes within micronuclei are subject to extensive DNA damage and centromeric identity loss, failing to assemble functional kinetochores and being recurrently mis-segregated during ensuing cell divisions in preimplantation development. To uncover the underlying causes for the increased propensity for chromosome mis-segregation in embryos, live imaging and loss-of-function approaches were used to examine the effectiveness of the mitotic safeguard mechanism, the Spindle Assembly Checkpoint (SAC). These studies demonstrated that the SAC normally functions to prevent segregation errors during preimplantation development but SAC signaling at misaligned chromosomes fails to delay anaphase. Moreover, SAC failure in embryos is most evident during mid-preimplantation development, independent of cell size. Partial inhibition of SAC target, the Anaphase Promoting Complex (APC/C), extended mitosis and reduced chromosome segregation errors in embryos. These studies have uncovered deficient SAC function during preimplantation development as a major cause for the high incidence of lagging chromosomes in embryos, which result in repeated mis-segregation of single chromosomes in a manner that necessarily causes mosaic aneuploidy. Additionally, this work provides proof-of-principle demonstration that pharmacological modulation of SAC-APC/C signalling can avert chromosome segregation errors in the early embryo. Altogether, these findings present new insights into the causes and nature of chromosome mis-segregation in embryos, providing novel mechanistic explanations for the occurrence of mosaicism that will have substantial implications for the detection and potential therapeutic prevention of aneuploidy in preimplantation embryos.
47
FRČKOVÁ, Karolína. "Analýza čtenářské úrovně žáků 1. - 3. ročníků se zaměřením na genetickou metodu čtení." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-394524.
Full textAbstract:
The diploma thesis deals with the teaching of the first reading focused on the Genetic method. It is divided into theoretical and research part. The theoretical part contains an overview of currently used methods of teaching reading. The Genetic method is described from the historical and present point of view. Also included are an overview of available textbooks for teaching this method. Also it deals with the basic features of reading performance, with the reading level of pupils through diagnostic examinations and with working with lagging readers. The research part deals with the analysis of reading level of pupils of the 1st - 3rd year of the Genetic method. The analysis was performed using diagnostic examinations, which were recorded and subsequently analyzed on the basis of basic reading characters. The research is focused primarily on mistakes against the qualities of reading, which are detailed and compared.