Relevant bibliographies by topics / Lambda phage

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Lambda phage'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

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Journal articles on the topic "Lambda phage"

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Hecht, Michael H., and Robert T. Sauer. "Phage lambda repressor revertants." Journal of Molecular Biology 186, no. 1 (November 1985): 53–63. http://dx.doi.org/10.1016/0022-2836(85)90256-6.

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Poteete, A. R., and A. C. Fenton. "Efficient double-strand break-stimulated recombination promoted by the general recombination systems of phages lambda and P22." Genetics 134, no. 4 (August 1, 1993): 1013–21. http://dx.doi.org/10.1093/genetics/134.4.1013.

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Abstract To examine bacteriophage recombination in vivo, independent of such other processes as replication and packaging, substituted lambda phages bearing restriction site polymorphisms were employed in a direct physical assay. Bacteria were infected with two phage variants; DNA was extracted from the infected cells and cut with a restriction endonuclease. The production of a unique recombinant fragment was measured by Southern blotting and hybridization with a substitution sequence-specific probe. High frequency recombination was observed under the following conditions: the substituted lambda phages infected a wild-type host cell bearing a lambda repressor-expressing plasmid designed to shut down phage transcription and inhibit phage DNA replication as well. The same plasmid expressed the lambda red and gam genes. In addition, the host cell bore a second plasmid which expressed the EcoRI restriction-modification system. Both phage chromosomes possessed a single EcoRI site in the middle of the marked substitution sequence; however, as the site was modified in one of the parent phages, only the other partner was cut. Recombination was found to be dependent upon (1) red, (2) recA, (3) inactivation of the host recBCD function, either by Gam protein or by mutation and (4) double-strand breaks. The homologous recombination system of phage P22 could substitute for that of lambda.
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Ghaemi, Amir, Alijan Tabaraei, Pooria Gill, Hoorieh Soleimanja, and Ali Gorji. "Lambda Phage Nanoparticles for Targetomics." Biotechnology(Faisalabad) 11, no. 2 (February 15, 2012): 95–99. http://dx.doi.org/10.3923/biotech.2012.95.99.

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Murray, Noreen E. "The impact of phage lambda: from restriction to recombineering." Biochemical Society Transactions 34, no. 2 (March 20, 2006): 203–7. http://dx.doi.org/10.1042/bst0340203.

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Experiments using phage lambda provided early insights into important molecular mechanisms, including genetic recombination and the control of gene expression. Before recombinant DNA technology, the use of lambda, most particularly lambda transducing phages, illustrated the importance of cloning bacterial genes, already providing some insight into how to use cloned genes to advantage. Subsequently, lambda made significant contributions to recombinant DNA technology, including the early generation of genomic and cDNA libraries. More recently, lambda genes associated with recombination have enabled techniques referred to as ‘recombineering’ to be developed. These techniques permit the refined manipulation, including mutation, of foreign genes in Escherichia coli and their subsequent return to the donor organism.
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Blasche, Sonja, Stefan Wuchty, Seesandra V. Rajagopala, and Peter Uetz. "The Protein Interaction Network of Bacteriophage Lambda with Its Host, Escherichia coli." Journal of Virology 87, no. 23 (September 18, 2013): 12745–55. http://dx.doi.org/10.1128/jvi.02495-13.

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Although most of the 73 open reading frames (ORFs) in bacteriophage λ have been investigated intensively, the function of many genes in host-phage interactions remains poorly understood. Using yeast two-hybrid screens of all lambda ORFs for interactions with its hostEscherichia coli, we determined a raw data set of 631 host-phage interactions resulting in a set of 62 high-confidence interactions after multiple rounds of retesting. These links suggest novel regulatory interactions between theE. colitranscriptional network and lambda proteins. Targeted host proteins and genes required for lambda infection are enriched among highly connected proteins, suggesting that bacteriophages resemble interaction patterns of human viruses. Lambda tail proteins interact with both bacterial fimbrial proteins andE. coliproteins homologous to other phage proteins. Lambda appears to dramatically differ from other phages, such as T7, because of its unusually large number of modified and processed proteins, which reduces the number of host-virus interactions detectable by yeast two-hybrid screens.
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Wu, W. F., S. Christiansen, and M. Feiss. "Domains for protein-protein interactions at the N and C termini of the large subunit of bacteriophage lambda terminase." Genetics 119, no. 3 (July 1, 1988): 477–84. http://dx.doi.org/10.1093/genetics/119.3.477.

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Abstract The large subunit of phage lambda terminase, gpA, the gene product of the phage A gene, interacts with the small subunit, gpNul, to form functional terminase. Terminase binds to lambda DNA at cosB to form a binary complex. The terminase:DNA complex binds a prohead to form a ternary complex. Ternary complex formation involves an interaction of the prohead with gpA. The amino terminus of gpA contains a functional domain for interaction with gpNul, and the carboxy-terminal 38 amino acids of gpA contain a functional domain for prohead binding. This information about the structure of gpA was obtained through the use of hybrid phages resulting from recombination between lambda and the related phage 21. lambda and 21 encode terminases that are analogous in structural organization and have ca. 60% sequence identity. In spite of these similarities, lambda and 21 terminases differ in specificity for DNA binding, subunit assembly, and prohead binding. A lambda-21 hybrid phage produces a terminase in which one of the subunits is chimeric and had recombinant specificities. In the work reported here; a new hybrid, lambda-21 hybrid 67, is characterized. lambda-21 hybrid 67 is the result of a crossover between lambda and 21 in the large subunit genes, such that the DNA from the left chromosome end is from 21, including cosB phi 21, the 1 gene, and the first 48 codons for the 2 gene. The rest of the hybrid 67 chromosome is lambda DNA, including 593 codons of the A gene. The chimeric gp2/A of hybrid 67 binds gp1 to form functional terminase.(ABSTRACT TRUNCATED AT 250 WORDS)
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Stahl, F. W., C. E. Shurvinton, L. C. Thomason, S. Hill, and M. M. Stahl. "On the clustered exchanges of the RecBCD pathway operating on phage lambda." Genetics 139, no. 3 (March 1, 1995): 1107–21. http://dx.doi.org/10.1093/genetics/139.3.1107.

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Abstract Lytic cycle crosses of Red- Gam- phage lambda were conducted in rec+ Escherichia coli carrying one or another plasmid with homology to lambda. Lambda x lambda recombinants and lambda x plasmid recombinants were formed by RecBCD-mediated recombination. We showed previously that the act of recombining with a plasmid alters the disposition of selected lambda x lambda exchanges. This work reports that the relationships between the lambda x plasmid and the lambda x lambda exchanges is unaltered by the removal from one lambda parent of the homology shared with the plasmid. This result supports our view that a reciprocal exchange, allowing for cointegrate formation, is associated with but mechanistically separable from a (presumably) nonreciprocal lambda x lambda exchange. The nature of this relationship is independent of lambda's Rap function, which is shown to alter the ratio of cointegrate formation (splices) to marker pick-up (patches) in lambda x plasmid recombination mediated by the RecBCD pathway.
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Wróbel, B., S. Srutkowska, and G. Wegrzyn. "Biochemical and genetic analysis of lambdaW, the newly isolated lambdoid phage." Acta Biochimica Polonica 45, no. 1 (March 31, 1998): 251–59. http://dx.doi.org/10.18388/abp.1998_4308.

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Otherwise isogenic Escherichia coli CP78 (relA+) and CP79 (relA-) strains are commonly used in studies on the stringent control, the bacterial response to amino acid starvation. We found that these strains are lysogenic for a phage which is spontaneously induced with a low frequency, producing virions able to infect other E. coli strains. Genetic studies, restriction analysis of the phage DNA genome, and electron microscopy revealed that this phage is very similar to, but not identical with, bacteriophage lambda. We called the newly isolated phage lambdaW, and found that most of CP78/CP79 ancestor strains are lysogenic for this phage.
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Bustamante, C., J. Marko, E. Siggia, and S. Smith. "Entropic elasticity of lambda-phage DNA." Science 265, no. 5178 (September 9, 1994): 1599–600. http://dx.doi.org/10.1126/science.8079175.

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Stahl, F. W., M. S. Fox, D. Faulds, and M. M. Stahl. "Break-join recombination in phage lambda." Genetics 125, no. 3 (July 1, 1990): 463–74. http://dx.doi.org/10.1093/genetics/125.3.463.

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Abstract In phage lambda, when DNA replication is blocked, recombination mediated by the Red pathway occurs only near the double-chain break site, cos, that defines the termini of the virion chromosome. The recombinants initiated by cos contain newly synthesized DNA near cos, in amount corresponding to a few percent of the length of lambda. A restriction enzyme cut delivered to one parent far from cos results in elevated recombination near the restriction site. Recombinants induced by this cut have a similarly small amount of DNA synthesis in these replication-blocked crosses. When restriction cuts are introduced in the presence of normal amounts of all of the DNA replication enzymes, many of the resulting recombinants still enjoy, at most, a small amount of DNA synthesis associated with the exchange event. Thus, these experiments fail to support the previously considered possibility that Red-mediated recombination in lambda proceeds largely through a break-copy pathway.
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Dissertations / Theses on the topic "Lambda phage"

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Al-Kaabawi, Naer. "Structural study of phage lambda proteins." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/19904/.

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Lambda phage proteins Four tail proteins of the Lambda bacteriophage, Rap endonuclease, NinH, Ea31 and Ea10, have previously been expressed in E. coli. Here, the methods are reported that were used to optimize the expression, purification and crystallization of these proteins. The structure determination of Ea10 is described. No crystals have yet been obtained for the purified full-length Rap endonuclease. Therefore, two truncated versions of the Rap endonuclease, which removed the first 30 and 70 residues of the disordered N-terminus, were produced to potentially increase the chance of protein crystallization. Overexpression experiments for NinH and Ea31 proteins were carried out with a His- tag or an MBP-tag, respectively, for solubility reasons. Both proteins were purified and set up in many crystallization trials. Crystals were not observed. Although tag cleavage for these proteins was performed to increase possibilities of crystallization, It was difficult to obtain a suitable level of purified protein for setting up crystallization trials. Heavy-atom derivatized crystals were obtained for Ea10, from which its structure was solved by X-ray diffraction to 2.7 Å. It was found to form a dimeric structure with beta strands swapped between a beta sheet observed in each monomer. As yet, no strongly homologous structures have been found for Ea10 to help predict its main function. Structural comparisons for Ea10 via the Dali Server suggest a notable similarity with part of the Q-beta replicase core complex, indicating an association with RNA. Unpublished data from the laboratory of Dr. Gary Sharples (University of Durham, UK) suggests that it might have a DNA binding capability. However, assays described here have not been able to confirm this. Experiments are still ongoing to unravel the mystery of the Ea10 function. Structure determination for the full length DnaD protein of Bacillus subtilis, which is a 232 amino acid primosomal protein that binds to supercoiled forms of DNA and converts them to open forms without nicking, was attempted, involving the N- and C-terminal domains which have never been solved together. Both domain structures (N-terminal and C-terminal) were published independently using crystallography and NMR assay, respectively. High resolution crystals (1.6 Å) with different space groups were collected. These crystals were confirmed as the N-terminal domain hits. Despite the use of a protease inhibitor was used for the prevention of a protein cleavage, N-terminal crystals were formed. Protein-protein interaction assay with DnaA protein for stability increase has not given any progress.
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St-Pierre, François Ph D. Massachusetts Institute of Technology. "Determination of cell fate selection during phage lambda Infection." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/85701.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2009.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages. 109-121).
Bacteriophage lambda infection of Escherichia coli can result in distinct cell fate outcomes: for example, some cells lyse while others survive as lysogens. A quantitative molecular model of lambda infection supports the hypothesis that spontaneous differences in the timing of individual molecular events during lambda infection leads to variation in the selection of cell fates. Building from this analysis, the lambda lysis-lysogeny decision now serves as a paradigm for how intrinsic biomolecular noise can influence cellular behavior, drive developmental processes, and produce population heterogeneity. The aim of this thesis is to re-evaluate lambda as a paradigm for stochastic behavior by determining whether and to what extent variation in cell fate selection results from pre-existing cell-cell differences rather than chance events during infection. I find that physical differences among cells present prior to infection can control lambda developmental outcomes. Specifically, variation in cell volume at the time of infection can be used to predict cell fate: small cells tend to produce lysogens while larger cells favor lytic growth. I then present evidence that the apparent sensitivity to host volume is encoded by components of the lambda regulatory network acting upstream or at the level of CII, a critical regulator of the lambda lysis-lysogeny decision. I also detail the construction and evaluation of new strains, tools and methodology to size-fractionate populations of cells, to detect lambda infection and gene expression at the single cell level, and to enumerate individual phage particles. My results motivate further research to understand how and to what extent natural biological systems tolerate, buffer or correct for spontaneous molecular variation during development in order to produce deterministic behavior.
by François St-Pierre.
Ph. D.
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Sun, Yuting. "Confinement and adsorption of end-grafted lambda-phage DNAs under bio-adhesive membranes." Strasbourg, 2010. http://www.theses.fr/2010STRA6184.

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Ma thèse est une contribution à la compréhension du rôle joué par les macromolécules dans la formation d'un contact adhésif entre des membranes bio-fonctionnelles de phospholipides. Nous étudions l'étalement d'un bicouche de DOPC sur un tapis d'ADNs du phage lambda, greffés par leurs deux extrémités. Le processus d'étalement a pour résultat de râcler et d'agrafer les chaînes entre la membrane et le substrat. La forme finale d'un ADN agrafé dépend des deux paramètres que sont la tension interne de la chaîne et les forces appliquées par la bicouche. Nous montrons qu'en utilisant la relation force-extension bien connue pour une molécule d'ADN, nous pouvons révéler les forces mises en jeu durant la formation de la zone d'adhésion. Nous calculons également la distribution spatiale des monomères des segments d'ADN qui ne sont pas confinés sous la membrane, mais émergent de la zone d'adhésion, et fluctuent dans la limite des contraintes géométrique du système. Finalement nous contrôlons les conformations et la dynamique des ADN greffés en jouant sur la concentration d'AzoTAB, un agent compactant photosensible de l'ADN
My PhD is a contribution towards the understanding of the role played by bio-macromolecules in the formation of the adhesive contact between bio-functional phospholipid membranes. We study the spreading of a biotinylated DOPC bilayer on a carpet of double end-grafted λ-phage DNAs. The spreading process scrapes and staples the chains between the membrane and the substrate. The final stapled DNA shape is a function of both the internal chain tension and the forces applied by the bilayer. We show that by using the well known force extension relationship for a DNA molecule we can reveal the forces at play during the formation of the adhesion patch. We also compute the monomer distribution of the segments of the DNA chains that are not confined under the membrane but emerge from the membrane side and fluctuate within the geometric boundaries of the system. Finally we control the conformations and the dynamics of the tethered DNAs by using AzoTAB concentration, a photosensitive compacting agent of the DNA chains
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Martin, Christopher B. "Riboflavin photosensitized inactivation of lambda phage in PBS an action spectrum and mechanistic investigation /." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1087497359.

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Thesis (Ph. D.)--Ohio State University, 2004.
Title from first page of PDF file. Document formatted into pages; contains xviii, 167 p.; also includes graphics (some col.) Includes bibliographical references (p. 115-121). Available online via OhioLINK's ETD Center
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Harkki, Anu. "An extension of the host range of phage [lambda] Salmonella typhimurium as a model /." Espoo : Technical Research Centre of Finland, 1987. http://books.google.com/books?id=rCNrAAAAMAAJ.

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Ananthanpillai, Balaji. "Stochastic Simulation of the Phage Lambda System and the Bioluminescence System Using the Next Reaction Method." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1259080814.

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Tolun, Gokhan. "More than the Sum of Its Parts: Physical and Mechanistic Coupling in the Phage Lambda Red Recombinase." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/29.

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In many dsDNA viruses, a single-strand-annealing homologous recombination (SSA) reaction is catalyzed by a pair of proteins. In phage lambda, this system is called Red, and is composed of lambda exonuclease (Lambda-Exo, a 5' to 3' dsDNA exonuclease), and Red-Beta (a ssDNA binding protein and annealase). I examined the physical and mechanistic coupling of Lambda-Exo and Red-Beta and confirmed that these proteins form a complex with a 1:1 subunit stoichiometry. The size of this complex was shown to be close to one MDa, possibly composed of 12 Lambda-Exo and 12 Red-Beta monomers. Red-Beta decreased the extent of digestion of dsDNA by Lambda-Exo, possibly by preventing its rebinding. The processivity of Lambda-Exo was not affected by Red-Beta, but the dwell-time of Lambda-Exo was significantly increased by Red-Beta. These effects of Red-Beta on Lambda-Exo may have important roles in controlling the SSA reaction by preventing hyper-resection of DNA, and/or by stabilizing Lambda-Exo/DNA complexes. The previous observations that Red-Beta protects ssDNA from nucleases and that SSB inhibits Red-Beta assembly onto ssDNA were confirmed and strengthened by our results. We determined that Red-Beta inhibits SSB binding to nascent ssDNA generated by Lambda-Exo. This strongly suggests that generation of nascent ssDNA by Lambda-Exo is coupled to assembly of Red-Beta onto nascent ssDNA. We describe two models for this coupled assembly: Model One suggests that Lambda-Exo loads Red-Beta on nascent ssDNA providing a kinetic advantage over SSB, and Model Two proposes that the complex of Lambda-Exo and Red-Beta feeds ssDNA directly onto the dodecameric Red-Beta ring. It was suggested that Lambda-Exo forms a topological link with nascent ssDNA, thereby making digestion highly processive. We challenged this model by removing the nascent ssDNA with ExoI during a Lambda-Exo digestion reaction. We observed that the nascent ssDNA was a major contributor to the processivity of Lambda-Exo since removal of nascent ssDNA resulted in a drastic decrease in the processivity of Lambda-Exo. This is the first demonstration that DNA is a processivity factor, strengthening the view that processive DNA processing enzymes should be thought of as nucleoprotein complexes that must be kinetically treated as both substrate and enzyme.
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Werts, Catherine. "Contributions a l'etude de la proteine lamb d'escherichia coli k-12 et de la proteine j du phage lambda." Paris 6, 1994. http://www.theses.fr/1994PA066285.

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Mon travail experimental porte sur l'etude d'une proteine de membrane externe d'escherichia coli k-12, la proteine lamb, egalement appelee maltoporine. Lamb permet specifiquement la translocation au travers de la membrane externe des maltodextrines, ensuite prises en charge par les autres constituants du systeme maltose. Cette proteine homotrimerique possede vraisemblablement une structure comparable a celle des porines organisees en tonneaux b. En absence de donnees cristallographiques a haute resolution de la structure de lamb, nous nous sommes interesses au repliement de cette proteine dans la membrane, en utilisant comme approche, la comparaison de l'antigenicite, des fonctions et des sequences de maltoporines d'autres enterobacteries que e. Coli k-12. Les resultats fournissent des indications quant a l'organisation structurale et fonctionnelle de la proteine lamb. Par ailleurs, la proteine lamb constitue le recepteur membranaire d'e. Coli permettant l'infection par le phage lambda (). Les mecanismes d'adsorption a la surface de la bacterie puis d'injection de l'adn du phage sont tres peu connus. Le phage s'adsorberait sur le recepteur par l'intermediaire de la fibre terminale, constituee par la proteine j, ce qui permettrait ensuite l'ejection de l'adn. Nous nous sommes interesses a l'interaction entre les proteines lamb et j. Pour cela, nous avons selectionne et analyse une serie de phages mutants tres particuliers, capables d'utiliser en plus de la proteine lamb sauvage, des recepteurs lamb alteres, comportant des mutations qui conferent la resistance au phage lambda sauvage. Les resultats confirment que la proteine j est bien impliquee dans cette interaction mais soulevent des questions quant a la nature de cette interaction. Ce manuscrit comprend tout d'abord une revue bibliographique qui traite, d'une part, de l'etude de la topologie et de l'organisation fonctionnelle de la proteine lamb, et d'autre part, des premieres etapes de l'infection d'e. Coli par le phage lambda et de son interaction avec le recepteur lamb. Les resultats experimentaux presentes dans les articles, sont egalement inclus et discutes dans la revue. Les donnees bibliographiques concernant les recepteurs et les mechanismes impliques dans l'interaction entre e. Coli ou s. Typhimurium et d'autres phages que lambda, sont compilees en annexe de la these
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Henry, Matthew S. "Characterization of a lambdoid phage gene encoding a host cell attachment spike." Bowling Green, Ohio : Bowling Green State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1214189208.

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Vieu, Erwann. "Dissection du mécanisme de terminaison-antiterminaison au niveau du terminateur tR1 du phage lambda : application à l'étude des complexes ARN-protéine in vivo." Orléans, 2004. http://www.theses.fr/2004ORLE2075.

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Chez Escherichia coli la terminaison de la transcription peut intervenir selon deux mécanismes distincts : tout d'abord la terminaison intrinsèque qui correspond à une séquence ADN, codant pour une structure en tige boucle riche en GC suivie d'une répétition d'uridine sur l'ARN, induisant le relargage de l'ARN polymérase. Le second mécanisme est gouverné par un facteur de terminaison nommé Rho qui gouverne environ 50% des évènements de terminaison chez E. Coli. Au cours de ma thèse, je me suis interessé à ce deuxième mécanisme, et plus particulièrement à sa régulation in vivo (antiterminaison). Rho, sous la forme d'un anneau héxamèrique, se fixe à l'ARN naissant au niveau d'un site d'entrée (également appelé RUT), puis utilise son activité ATPase pour longer l'ARN et disssocier le complexe ternaire d'élongation stoppé au niveau d'un site de pause. Les terminateurs Rho-dépendants sont assez mal définis et peu d'entre eux ont été analysés en détail. Le terminateur tR1 du phage lambda (l) est le terminateur Rho-dépendant le plus étudié à la fois in vitro et in vivo. La terminaison Rho-dépendante au niveau de ce terminateur est gouvernée principalement par les séquences localisées en 5', codant deux régions du transcript nommées RUTA et RUTB. Ces deux régions sont séparées par le motif ARN BOXB qui n'est pas indispensable à l'action de Rho mais sert, dans le mécanisme d'antiterminaison, de site de fixation pour la protéine N du phage l. Grâce à un système minimal d'étude in vivo, nous avons montré que le motif BOXB possède une fonction double dans les mécanismes de terminaison/antiterminaison au niveau de ltR1 régulant l'expression temporale du génome du phage l. Sous la forme d'une tige boucle hautement structurée, BOXB agit comme un lien permettant de placer RUTA et RUTB l'un à coté de l'autre pour une interaction optimale avec Rho et une terminaison efficace. A l'inverse, la fixation de la protéine N sur BOXB induit l'antiterminaison au niveau de ltR1 en empèchant l'accès de Rho à l'ARN. Ce double rôle à été démontré in vivo en substituant au couple N/BOXB la "coat protein" du phage MS2 et son motif cible en tige boucle. En complément de ce travail, j'ai utilisé cette faculté d'un complexe ribonucléoprotéique de bloquer la terminaison Rho-dépendante, pour développer une nouvelle approche d'étude, in vivo, des complexes ARN-protéine.
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Books on the topic "Lambda phage"

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Ptashne, Mark. A genetic switch: Phage [lambda] and higher organisms. 2nd ed. Cambridge, Mass: Cell Press, 1992.

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Ptashne, Mark. A genetic switch: Gene control and phage(lambda). Cambridge, Ma: Cell, 1987.

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Ptashne, Mark. A genetic switch: Gene control and phage [lambda]. Cambridge, Mass: Cell Press, 1987.

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A genetic switch: Gene control and phage [lamda]. Palo Alta., Calif: Cell Press & Blackwell Scientific Publications, 1986.

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Ptashne, Mark. Genetic Switch: Phage Lambda Revisited. 3rd ed. Cold Spring Harbor Laboratory Press, 2004.

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Ptashne, Mark. A Genetic Switch: Gene Control and Phage. Blackwell Science Inc, 1986.

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Shinder, Gayle Ann. Studies on the binding of bacterial and lambda phage proteins to the "cos" site of bacteriophage lambda DNA. 1989.

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Mah, Thien-Fah. A structure/function analysis of the interaction of the E.coli NusA protein with RNA polymerase, the phage [lambda] N protein, and nut site RNA. 1999.

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Deruelle, Nathalie, and Jean-Philippe Uzan. The Lambda-CDM model of the hot Big Bang. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198786399.003.0059.

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This chapter introduces the Lambda-CDM (cold dark matter) model. In 1948, under the impetus of George Gamow, Robert Hermann, Ralph Alpher, and Hans Bethe in particular, relativistic cosmology entered the second phase of its history. In this phase, physical processes, in particular, nuclear and atomic processes, are taken into account. This provides two observational tests of the model: primordial nucleosynthesis, which explains the origin of light nuclei, and the existence of the cosmic microwave background, and it establishes the fact that the universe has a thermal history. Study of the large-scale structure of the universe then indicates the existence of dark matter and a nonzero cosmological constant. This model, known as the Λ‎CDM model, is the standard model of contemporary cosmology.
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Book chapters on the topic "Lambda phage"

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Weil, Clifford F., and Thomas E. Bureau. "Construction of a Genomic Library in Lambda Phage." In The Maize Handbook, 595–98. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2694-9_105.

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Matvienko, N. I., I. N. Troyanovskaya, L. A. Zheleznaya, and O. B. Yarchuk. "Host Vector System with the PR, Promoter of Phage Lambda." In Gene Manipulation and Expression, 225–39. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-011-6565-5_17.

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Mattiacio, Jonelle L., Matt Brewer, and Stephen Dewhurst. "Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform." In Methods in Molecular Biology, 245–53. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6869-5_14.

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Burmeister, Alita R., Rachel M. Sullivan, and Richard E. Lenski. "Fitness Costs and Benefits of Resistance to Phage Lambda in Experimentally Evolved Escherichia coli*." In Evolution in Action: Past, Present and Future, 123–43. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39831-6_11.

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Banik, Sebika K., Debika K. Banik, and Kalyan Bhuyan. "Phase Portraits of Higher Dimensional FRW Cosmology in $$R^pexp(\lambda R)$$ Gravity Filled with Non-perfect Fluid." In XXII DAE High Energy Physics Symposium, 333–36. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-73171-1_76.

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Popov, Andrey. "Non-Euclidean phase spaces. Discrete nets on the Lobachevsky plane and numerical integration algorithms for $$\Lambda^2$$ -equations." In Lobachevsky Geometry and Modern Nonlinear Problems, 259–90. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05669-2_6.

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Zyskind, Judith W., and Sanford I. Bernstein. "LAMBDA PHAGE MANIPULATIONS." In Recombinant DNA Laboratory Manual, 135–49. Elsevier, 1989. http://dx.doi.org/10.1016/b978-0-12-784400-8.50014-8.

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Zyskind, Judith W., and Sanford I. Bernstein. "LAMBDA PHAGE MANIPULATIONS." In Recombinant Dna Laboratory Manual, 135–49. Elsevier, 1992. http://dx.doi.org/10.1016/b978-0-12-784401-5.50014-9.

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"Lambda Phage (λ)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics, 1078–82. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_9186.

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"Stochastic Simulation of the Phage Lambda Gene Regulatory Circuitry." In Quantitative Biology, 317–58. CRC Press, 2012. http://dx.doi.org/10.1201/b12676-18.

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Conference papers on the topic "Lambda phage"

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Wei Tian, Hongyuan Zhu, Xue Lei, and Ping Ao. "Extrinsic vs. intrinsic noises in phage lambda genetic switch." In 2011 IEEE International Conference on Systems Biology (ISB). IEEE, 2011. http://dx.doi.org/10.1109/isb.2011.6033122.

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Frazier, D., Shu Wha Lin, J. Ware, Kenneth Smith, Howard Reisner, M. DeSerres, A. Wallmark, R. Ljung, I. M. Nilsson, and D. W. Stafford. "MAPPING OF 6 MONOCLONAL ANTIBODIES TO HUMAN FACTOR IX." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643565.

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In order to map the regions of human factor IX recognized by monoclonal antibodies we have inserted random fragments of the coding region of the cDNA for human factor IX into the lambda phage expression vector, lambda gtll. The resultant recombinant phage were screened with monoclonal antibodies, the immunoreactive phage were isolated, and the DNA of the inserted fragment was sequenced to determine which amino acids were immunoreactive. This data, coupled with data obtained from the use of specific fragments of human factor IX expressed in E. coli from a T7 phage promoter, has allowed us to map the location of several epitopes on the surface of the factor IX molecule. In those cases where the antibodies are specific for human factor IX, additional narrowing of the epitope is possible by comparing the amino acid sequence of human factor IX to the bovine molecule. Six monoclonal antibodies from 3 different laboratories have been mapped. The immunodominant epitopes appear to be the amino terminus of the activation peptide, the amino terminus of the heavy chain and the epidermal growth factor domains.
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Samaratunga, Dulip, Ruisheng Wang, and Ratneshwar Jha. "Lamb Wave Instantaneous Phase Based Method for Quantitative Level of Delamination Damage in Composite Structures." In ASME 2012 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/smasis2012-8216.

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In this study, we investigate the interactions of Lamb wave A0 mode with different sizes of delaminations in composites using finite element code Abaqus®. According to Lamb wave dispersion curves, the group velocity of A0 mode increases rapidly as the frequency-thickness increases in the relatively low frequency region. In the delamination region, the frequency-thickness product decreases compared to the healthy laminate since the damage causes ply separation at the lamina interface. In the current study this observation is investigated in detail using finite element simulations. The resulting phase delay is analyzed by Empirical Mode Decomposition (EMD) and instantaneous phase approach. Finite element simulations are performed using Abaqus® and signal processing is performed in joint time-frequency domain using Hilbert-Huang Transform (HHT) method. The unwrapped instantaneous phase difference is correlated with the extent of delamination (quantitative level of damage).
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Ashraf, Adnan, Najam Abbas Naqvi, and Zohaib Afzal. "Ambiguity Resolution in Carrier Phase Based Positioning Using Lambda Method." In 2019 Sixth International Conference on Aerospace Science and Engineering (ICASE). IEEE, 2019. http://dx.doi.org/10.1109/icase48783.2019.9059154.

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Giorgi, Gabriele, and Peter J. G. Teunissen. "Carrier phase GNSS attitude determination with the Multivariate Constrained LAMBDA method." In 2010 IEEE Aerospace Conference. IEEE, 2010. http://dx.doi.org/10.1109/aero.2010.5446910.

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Lyuboshitz, Valery V., and Vladimir L. Lyuboshitz. "Possible Effect of Mixed Phase and Deconfinement upon Spin Correlations in the \(\Lambda \bar{\Lambda }\) Pairs Generated in Relativistic Heavy-Ion Collisions." In Proceedings of the 14th International Conference on Meson-Nucleon Physics and the Structure of the Nucleon (MENU2016). Journal of the Physical Society of Japan, 2017. http://dx.doi.org/10.7566/jpscp.13.020025.

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Lyuboshitz, Valery V., and Vladimir Lvovich Lyuboshitz. "Possible effect of mixed phase and deconfinement upon spin correlations in the $\Lambda \bar{\Lambda}$ pairs generated in relativistic heavy-ion collisions." In XVII International Conference on Hadron Spectroscopy and Structure. Trieste, Italy: Sissa Medialab, 2018. http://dx.doi.org/10.22323/1.310.0226.

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Lyuboshitz, Valery V., and Vladimir Lvovich Lyuboshitz. "Possible effect of mixed phase and deconfinement upon spin correlations in the $\Lambda \bar{\Lambda}$ pairs generated in relativistic heavy-ion collisions." In The European Physical Society Conference on High Energy Physics. Trieste, Italy: Sissa Medialab, 2017. http://dx.doi.org/10.22323/1.314.0653.

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Lyuboshitz, Valery V., and Vladimir Lvovich Lyuboshitz. "Possible effect of mixed phase and deconfinement upon spin correlations in the $\Lambda \bar{\Lambda}$ pairs generated in relativistic heavy-ion collisions." In XXVII International Symposium on Lepton Photon Interactions at High Energies. Trieste, Italy: Sissa Medialab, 2016. http://dx.doi.org/10.22323/1.245.0059.

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Lyuboshitz, Valery V., and Vladimir Lvovich Lyuboshitz. "Possible effect of mixed phase and deconfinement upon spin correlations in the $\Lambda \bar{\Lambda}$ pairs generated in relativistic heavy-ion collisions." In 23rd International Spin Physics Symposium. Trieste, Italy: Sissa Medialab, 2019. http://dx.doi.org/10.22323/1.346.0034.

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Reports on the topic "Lambda phage"

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Simpson, W. A., and D. J. McGuire. Phase and group velocities for Lamb waves in DOP-26 iridium alloy sheet. Office of Scientific and Technical Information (OSTI), July 1994. http://dx.doi.org/10.2172/10171446.

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