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Journal articles on the topic 'Lamellar bone tissue'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Gupta, H. S., U. Stachewicz, W. Wagermaier, P. Roschger, H. D. Wagner, and P. Fratzl. "Mechanical modulation at the lamellar level in osteonal bone." Journal of Materials Research 21, no. 8 (2006): 1913–21. http://dx.doi.org/10.1557/jmr.2006.0234.

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The secondary osteon is the fundamental building block of compact cortical bone at the tissue level. Light and scanning electron microscopy have shown that the osteon consists of a laminated cylindrical composite of mineralized collagen fibril lamellae ∼5–7 μm thick. Using scanning nanoindentation and quantitative backscattered electron imaging on secondary osteons from the human femoral midshaft, we found that the indentation modulus shows a periodic variation between ∼24 GPa and ∼27 GPa within a single lamella. The average lamellar value remains nearly constant across the osteon and increase

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Donnelly, Eve, Rebecca M. Williams, Seth A. Downs, Michelle E. Dickinson, Shefford P. Baker, and Marjolein C. H. van der Meulen. "Quasistatic and dynamic nanomechanical properties of cancellous bone tissue relate to collagen content and organization." Journal of Materials Research 21, no. 8 (2006): 2106–17. http://dx.doi.org/10.1557/jmr.2006.0259.

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Cancellous bone plays a crucial structural role in the skeleton, yet little is known about the microstructure-mechanical property relationships of the tissue at the microscale. Cancellous tissue is characterized by a microstructure consisting of layers interspaced with transition zones with different proportions of collagen and mineral. In this study, the quasistatic and dynamic mechanical properties of lamellar and interlamellar tissue in human vertebrae were assessed with nanoindentation, and the collagen content and organization were characterized with second harmonic generation microscopy.

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Martínez-Reina, Javier, Javier García-Rodríguez, Juan Mora-Macías, Jaime Domínguez, and Esther Reina-Romo. "Comparison of the volumetric composition of lamellar bone and the woven bone of calluses." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 232, no. 7 (2018): 682–89. http://dx.doi.org/10.1177/0954411918784085.

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Woven tissue is mainly present in the bone callus, formed very rapidly either after a fracture or in distraction processes. This high formation speed is probably responsible for its disorganized microstructure and this, in turn, for its low stiffness. Nonetheless, the singular volumetric composition of this tissue may also play a key role in its mechanical properties. The volumetric composition of woven tissue extracted from the bone transport callus of sheep was investigated and compared with that of the lamellar tissue extracted from the cortical shell of the same bone. Significant differenc

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4

Carnelli, Davide, Pasquale Vena, Ming Dao, Christine Ortiz, and Roberto Contro. "Orientation and size-dependent mechanical modulation within individual secondary osteons in cortical bone tissue." Journal of The Royal Society Interface 10, no. 81 (2013): 20120953. http://dx.doi.org/10.1098/rsif.2012.0953.

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Anisotropy is one of the most peculiar aspects of cortical bone mechanics; however, its anisotropic mechanical behaviour should be treated only with strict relationship to the length scale of investigation. In this study, we focus on quantifying the orientation and size dependence of the spatial mechanical modulation in individual secondary osteons of bovine cortical bone using nanoindentation. Tests were performed on the same osteonal structure in the axial (along the long bone axis) and transverse (normal to the long bone axis) directions along arrays going radially out from the Haversian ca

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5

García, F., J. Camón, M. C. Manzanares, and J. Franch. "Backscattered Electron Imaging of the Calcified Tissues Present in Bone Healing." Veterinary and Comparative Orthopaedics and Traumatology 11, no. 02 (1998): 105–11. http://dx.doi.org/10.1055/s-0038-1632619.

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SummaryThe aspect of calcified tissues involved in fracture healing was studied by means of backscattered electron imaging. Bilateral transverse midshaft osteotomies were performed in the tibiae of 16 dogs. The osteotomies were reduced by means of a type II external skeletal fixator, and the clinical and radiographic course was assessed weekly until the moment of euthanasia, one, two, four and eight weeks after the operations. The osteotomized areas were removed and their structure examined in the scanning electron microscope, using backscattered electron images, to determine the general aspec

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Scarano, Antonio, Vito Crincoli, Adriana Di Benedetto, et al. "Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular “Critical Size” Defect." Stem Cells International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/9082869.

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Introduction. Adding stem cells to biodegradable scaffolds to enhance bone regeneration is a valuable option. Different kinds of stem cells with osteoblastic activity were tested, such as bone marrow stromal stem cells (BMSSCs). Aim. To assess a correct protocol for osteogenic stem cell differentiation, so BMSSCs were seeded on a bone porcine block (BPB). Materials and Methods. Bone marrow from six minipigs was extracted from tibiae and humeri and treated to isolate BMSSCs. After seeding on BPB, critical-size defects were created on each mandible of the minipigs and implanted with BPB and BPB/

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7

Klein, Nicole, Alexandra Houssaye, James M. Neenan, and Torsten M. Scheyer. "Long bone histology and microanatomy of Placodontia (Diapsida: Sauropterygia)." Contributions to Zoology 84, no. 1 (2015): 59—S15. http://dx.doi.org/10.1163/18759866-08401005.

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Placodontia, an enigmatic group of durophagous and in part heavily armoured animals, were members of Sauropterygia, the most diverse and successful group of Mesozoic marine reptiles. Microanatomy and histology of long bones of several armoured and non-armoured Placodontia were studied, covering most of their taxonomic breadth, to elucidate the paleoecology, physiology, and lifestyle of its members. Results reveal an unexpected and not phylogenetically or stratigraphically related disparity of microanatomical and histological features for the group. The non-armoured Paraplacodus and the heavily

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Borkhunova, Elena N. "The structure and locis minus resistentia of bone-tendon joints of the horse's finger flexors." Veterinariya, Zootekhniya i Biotekhnologiya 6, no. 103 (2022): 6–17. http://dx.doi.org/10.36871/vet.zoo.bio.202206001.

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We studied the peculiarities of the structure and functions of bone tendon compounds (enthusis). The subject of the study is a horse. Subject of investigation – places of attachment of tendons of superficial finger flexor, deep finger flexor. Light microscopy, polarization microscopy and biomechanics were used. The general patterns of the structure of enthesis that belong to the fibrous cartilage and fibrous types are established. In the enthesis of the fibrous cartilage type there are zones of tendon, fibrous cartilage, mineralized fibrous cartilage, lamellar bone tissue. Areas of tendon, ret

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9

Johnson, Kenneth A. "Histologic features of the healing of bone graft donor sites in dogs." American Journal of Veterinary Research 49, no. 6 (1988): 885–88. https://doi.org/10.2460/ajvr.1988.49.06.885.

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SUMMARY Healing of cancellous bone graft donor sites in the proximal tibial metaphysis of 12 healthy adult dogs was studied histologically. Cancellous bone was curetted from the metaphysis of the proximal end of the tibia, via a 1-cm diameter circular opening in the medial cortex. A hematoma and fibrovascular tissue filled the bone defect at 2 weeks. At 4 and 8 weeks, endosteal callus, composed initially of cartilage and woven bone and later of lamellar bone, filled the marrow cavity. At 12 weeks, the normal structural arrangement of lamellar bone and hematopoietic marrow was reestablished in

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10

Nosouhian, Saeid, Amin Davoudi, Mansour Rismanchian, Sayed Mohammad Razavi, and Hamidreza Sadeghiyan. "Comparing Three Different Three-dimensional Scaffolds for Bone Tissue Engineering: An in vivo Study." Journal of Contemporary Dental Practice 16, no. 1 (2015): 25–30. http://dx.doi.org/10.5005/jp-journals-10024-1630.

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ABSTRACT Introduction Three-dimensional Scaffold structure of synthetic biomaterials with their interconnected spaces seem to be a safe and effective option in supporting bone regeneration. The aim of this animal study was to compare the effectiveness of three different biocompatible scaffolds: bioglass (BG), demineralized bone matrix (DBM) and forstrite (FR). Materials and methods Four healthy dogs were anesthetized and the first to fourth premolars were extracted atraumatically in each quadrant. After healing, linear incision was prepared from molar to anterior segment and 4 defects in each

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Rubnikovich, S. P., I. S. Khomich, and Yu L. Denisova. "Morphological changes in the bone tissue around dental implants after low-frequency low-intensity ultrasound applications." Proceedings of the National Academy of Sciences of Belarus, Medical series 17, no. 1 (2020): 20–27. http://dx.doi.org/10.29235/1814-6023-2020-17-1-20-27.

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The article presents the results of a histological study of morphological changes in bone tissue around established dental implants after exposure to low-intensity, low-frequency ultrasound during dental implantation. Histological studies of tibia bone blocks were conducted in three groups of laboratory animals around installed dental implants, which were subjected to different modes of ultrasonic exposure. In the course of studies, it was found that the processes of osseointegration of dental implants in animals of all groups occurred without staging. In the early stages, granulation tissue w

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Rubnikovich, S. P., and I. S. Khomich. "Evaluation of histological changes in peri-implant bone tissue after ultrasound application at early healing stages." Stomatologist. Minsk, no. 3(30) (September 2018): 38–42. http://dx.doi.org/10.32993/stomatologist.2018.3(30).1.

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The aim was to study the nature of the morphological changes over time in the bone tissue around the implants under the influence of low-intensity pulsed ultrasound in the experiment. Materials and methods. Experimental studies were carried out on rabbits of the chinchilla breed, with dental implants installed in the tibia – two experimental groups with ultrasound and one control group. The animals were withdrawn from the experiment at 1, 2, 4 and 8 weeks and histological examination of the sections of peri-implant tissues was carried out. Results. The processes of osseointegration of dental i

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Tien, Lee W., Eun Seok Gil, Sang-Hyug Park, Biman B. Mandal, and David L. Kaplan. "Patterned Silk Film Scaffolds for Aligned Lamellar Bone Tissue Engineering." Macromolecular Bioscience 12, no. 12 (2012): 1671–79. http://dx.doi.org/10.1002/mabi.201200193.

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14

Degidi, Marco, Antonio Scarano, Maurizio Piattelli, and Adriano Piattelli. "Histologic Evaluation of an Immediately Loaded Titanium Implant Retrieved from a Human After 6 Months in Function." Journal of Oral Implantology 30, no. 5 (2004): 289–96. http://dx.doi.org/10.1563/0695.1.

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Abstract Clinical and histologic studies have demonstrated that immediate loading can be successfully used in implant dentistry. Many factors are thought to be of importance in obtaining mineralized tissues at the interface. This study describes the implant interface of an immediately loaded implant with a conical implant-abutment connection that had been inserted in the posterior mandible for 6 months. Histology showed that mineralized tissue was present at about 74% ± 6% of the implant interface. No gaps, fibrous tissue, or inflammatory infiltrate were present at the interface. The bone adja

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15

Hoffler, C. Edward, X. Edward Guo, Philippe K. Zysset, and Steven A. Goldstein. "An Application of Nanoindentation Technique to Measure Bone Tissue Lamellae Properties." Journal of Biomechanical Engineering 127, no. 7 (2005): 1046–53. http://dx.doi.org/10.1115/1.2073671.

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Measuring the microscopic mechanical properties of bone tissue is important in support of understanding the etiology and pathogenesis of many bone diseases. Knowledge about these properties provides a context for estimating the local mechanical environment of bone related cells that coordinate the adaptation to loads experienced at the whole organ level. The objective of this study was to determine the effects of experimental testing parameters on nanoindentation measures of lamellar-level bone mechanical properties. Specifically, we examined the effect of specimen preparation condition, inden

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16

Battistella, Elisa, Silvia Mele, S. Pietronave, et al. "Transformed Cuttlefish Bone Scaffolds for Bone Tissue Engineering." Advanced Materials Research 89-91 (January 2010): 47–52. http://dx.doi.org/10.4028/www.scientific.net/amr.89-91.47.

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Nature is full of many interesting things to work with, but many natural resources are also protected. In this view the recycling of aquaculture and fishery residues may lead to the manufacture of new devices and the isolation of new molecules with potential application in medicine. The aim of the present study was to explore the possibility to transform the cuttlefish bone into an hydroxyapatite scaffold suitable for bone tissue engineering application. The mixture of different lamellar porous structure of cuttlefish bone from the species Sepia Officinalis was selected and characterized, acco

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17

Popkov, A. V., N. A. Kononovich, E. N. Gorbach, S. I. Tverdokhlebov, Y. M. Irianov, and D. A. Popkov. "Bone Healing by Using Ilizarov External Fixation Combined with Flexible Intramedullary Nailing versus Ilizarov External Fixation Alone in the Repair of Tibial Shaft Fractures: Experimental Study." Scientific World Journal 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/239791.

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Purpose. Our research was aimed at studying the radiographic and histological outcomes of using flexible intramedullary nailing (FIN) combined with Ilizarov external fixation (IEF) versus Ilizarov external fixation alone on a canine model of an open tibial shaft fracture.Materials and Methods. Transverse diaphyseal tibial fractures were modelled in twenty dogs. Fractures in the dogs of group 1 (n=10) were stabilized with the Ilizarov apparatus while it was combined with FIN in group 2 (n=10).Results. On day 14, a bone tissue envelope started developing round the FIN wires. Histologically, we r

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Dedivitis, Rogério Aparecido, Márcio Abrahão, Manoel de Jesus Simões, Osvaldo Alves Mora, and Onivaldo Cervantes. "Aging histological changes in the cartilages of the cricoarytenoid joint." Acta Cirurgica Brasileira 19, no. 2 (2004): 136–40. http://dx.doi.org/10.1590/s0102-86502004000200010.

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PURPOSE: Analysis of ossification, bone marrow formation, perichondrium thickness, muscle fibers, collagen fibers and elastic fibers quantities of cricoid and arytenoid cartilages. Design: Correlation morphologic study. METHODS: Twenty-four cricoarytenoid joints were obtained from Caucasian male fresh cadavers divided into three groups with eight specimens in each: group I - adolescents, from 15 to 20; group II - adults, from 25 to 35; and group III - elderly, from 60 to 75. The specimens were stained with H-E; trichrome; Picrosirius; and elastic stain. Histometry was performed for quantitativ

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Zumbo, A., S. Casella, A. Di Rosa, S. Scianò, F. Fazio, and G. Piccione. "Levels of serum osteocalcin and some electrolytes in foal during the first six months of life (Brief Report)." Archives Animal Breeding 53, no. 2 (2010): 239–41. http://dx.doi.org/10.5194/aab-53-239-2010.

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Abstract. Bone is a dynamic tissue characterized by continuous bone formation and bone resorption. The transformation of the primordial part of the long bones (the cartilaginous matrix during the embryonal period) into the definitive bone (lamellar bone tissue) is completed after puberty. Osteocalcin, also called the vitamin k-dependent protein of bone and synthesized predominantly by osteoblasts and in lower way by odontoblasts, is incorporated into the extracellular matrix of bone (LEPAGE et al. 2001) and it may function as a useful indicator of the equine bone growth rate which decreases co

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Wingender, Brian, Yongliang Ni, Yifan Zhang, Curtis Taylor, and Laurie Gower. "Hierarchical Characterization and Nanomechanical Assessment of Biomimetic Scaffolds Mimicking Lamellar Bone via Atomic Force Microscopy Cantilever-Based Nanoindentation." Materials 11, no. 7 (2018): 1257. http://dx.doi.org/10.3390/ma11071257.

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The hierarchical structure of bone and intrinsic material properties of its two primary constituents, carbonated apatite and fibrillar collagen, when being synergistically organized into an interpenetrating hard-soft composite, contribute to its excellent mechanical properties. Lamellar bone is the predominant structural motif in mammalian hard tissues; therefore, we believe the fabrication of a collagen/apatite composite with a hierarchical structure that emulates bone, consisting of a dense lamellar microstructure and a mineralized collagen fibril nanostructure, is an important first step to

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Jakobsen, Thomas, Søren Kold, Jørgen Baas, Kjeld Søballe, and Ole Rahbek. "Sheep Hip Arthroplasty Model of Failed Implant Osseointegration." Open Orthopaedics Journal 9, no. 1 (2015): 525–29. http://dx.doi.org/10.2174/1874325001509010525.

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Early secure stability of an implant is important for long-term survival. We examined whether micromotion of implants consistently would induce bone resorption and formation of a fibrous membrane and thereby prevent osseointegration.One micromotion implant was inserted into one of the medial femoral condyles in ten sheep. The micromotion device consists of an anchor bearing a PMMA implant and a PE plug. During each gait cycle the PE plug will make the PMMA implant axially piston 0.5 mm. After 12 weeks of observation the bone specimens were harvested and a post-mortem control implant was insert

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Beltrán, Víctor, Benjamín Weber, Ricardo Lillo, et al. "Histomorphometric Analysis of Osseointegrated Grade V Titanium Mini Transitional Implants in Edentulous Mandible by Backscattered Scanning Electron Microscopy (BS-SEM)." Metals 11, no. 1 (2020): 2. http://dx.doi.org/10.3390/met11010002.

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The purpose of this study is to assess the use of grade V titanium mini transitional implants (MTIs) immediately loaded by a temporary overdenture. For this, a histomorphometric analysis of the bone area fraction occupancy (BAFO) was performed by backscattered scanning electron microscopy (BS-SEM). Four female patients were submitted to surgery in which two MTIs were installed and immediately loaded with a temporary acrylic prosthesis. During the same surgery, two regular diameter implants were placed inside the bone and maintained without mechanical load. After 8 months, the MTIs were extract

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23

Franch, J., J. Pastor, B. Franch, I. Durall, and M. C. Manzanares. "Back-Scattered Electron Imaging of a Non-Vertebral Case of Hypervitaminosis a in a Cat." Journal of Feline Medicine and Surgery 2, no. 1 (2000): 49–56. http://dx.doi.org/10.1053/jfms.2000.0065.

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We describe a clinical case of hypervitaminosis A in a cat. The main lesions were bony fusions of both the hip and stifle joints, without spinal involvement. A post-mortem study using back-scattered scanning electron microscopy (BEI-SEM) revealed that exostoses had formed around the joints without articular surface involvement. The more recently formed areas of bony proliferation were composed mainly of chondroid tissue surrounded by different degrees of woven bone. As the bony reaction occurred, remodelling of the trabeculae was observed which lead to progressive substitution of chondroid tis

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Fernández-Iglesias, Ángela, Rocío Fuente, Helena Gil-Peña, Laura Alonso-Durán, Fernando Santos, and José Manuel López. "The Formation of the Epiphyseal Bone Plate Occurs via Combined Endochondral and Intramembranous-Like Ossification." International Journal of Molecular Sciences 22, no. 2 (2021): 900. http://dx.doi.org/10.3390/ijms22020900.

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The formation of the epiphyseal bone plate, the flat bony structure that provides strength and firmness to the growth plate cartilage, was studied in the present study by using light, confocal, and scanning electron microscopy. Results obtained evidenced that this bone tissue is generated by the replacement of the lower portion of the epiphyseal cartilage. However, this process differs considerably from the usual bone tissue formation through endochondral ossification. Osteoblasts deposit bone matrix on remnants of mineralized cartilage matrix that serve as a scaffold, but also on non-minerali

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Brkovic, Bozidar, Milan Radulovic, and Vesna Danilovic. "Preimplant preparation of the extraction alveolus with the deproteinized bovine bone and calcium-sulphate." Vojnosanitetski pregled 63, no. 2 (2006): 181–85. http://dx.doi.org/10.2298/vsp0602181b.

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Background. Different materials are used to prevent the resorption of alveolar bone. The aim of this report was to show the radiographical and histological results prior to implant insertion, when a deproteinized bovine bone mineral (BioOss) and calcium-sulphate were placed into the extraction socket immediately after the tooth removal. Case report. A 22-year-old woman was scheduled for the removal of the second lower molar when the extraction socket was filled with BioOss covered with calcium-sulphate as a resorbable membrane. Primary closure of the surgical site was performed. Radiography wa

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Kolb, Christian, Torsten M. Scheyer, Kristof Veitschegger, et al. "Mammalian bone palaeohistology: a survey and new data with emphasis on island forms." PeerJ 3 (October 22, 2015): e1358. http://dx.doi.org/10.7717/peerj.1358.

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The interest in mammalian palaeohistology has increased dramatically in the last two decades. Starting in 1849 via descriptive approaches, it has been demonstrated that bone tissue and vascularisation types correlate with several biological variables such as ontogenetic stage, growth rate, and ecology. Mammalian bone displays a large variety of bone tissues and vascularisation patterns reaching from lamellar or parallel-fibred to fibrolamellar or woven-fibred bone, depending on taxon and individual age. Here we systematically review the knowledge and methods on cynodont and mammalian bone micr

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Rogoleva Gjurovski, Sonja, and Verica Toneva Stojmenova. "THE BENEFITS OF USING THE SOCKET SHIELD TECHNIQUE IN PARTIAL EXTRACTION THERAPY: AN ARTICLE REVIEW." MEDIS – International Journal of Medical Sciences and Research 1, no. 1 (2022): 21–24. http://dx.doi.org/10.35120/medisij010121r.

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The technique with socket shield is used like not total extraction therapy which is based on preserving segment from one of the sides on the root from the tooth that is going to be extracted. The main use of this technique is in cases for implant placement that is combined with grafting bone. The goal of this technique is to preserve as much as possible tissue from the periodontal ligament and also to spare the gingival tissue from unnecessary damaging during the therapy. Indications for this technique are : 1. To support and to preserve buccofacial bone part of extraction socket in cases that

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Rajashree Pradhan, Sajeeb Mondal, Bidisha Chakraborty, and Madhumita Paul. "Heterotopic Ossification at Uncommon Sites: A Case Series of 4 Rare Cases." Indian Journal of Public Health Research & Development 15, no. 2 (2024): 80–83. http://dx.doi.org/10.37506/r4ard424.

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Heterotopic ossification (HO) is a condition of formation of mature lamellar bone in the extra skeletal soft tissue where bone does not usually exist. It is most commonly seen in muscle tissue and central nervous system following trauma. In this case series, we have reported 4 rare cases of heterotopic bone formations at uncommon sites. One case of HO in clear cell renal cell carcinoma, one case of HO in tendoachilles, one case of HO in intramuscular vascular malformation and one case HO in abdominal incision scar. HO is a rare entity. In most of the cases exact etiology is unknown. Further st

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Cheng, Guoping, Liang Chen, Huanhuan Feng, Bo Jiang, and Yi Ding. "Preliminary Study on Fish Scale Collagen Lamellar Matrix as Artificial Cornea." Membranes 11, no. 10 (2021): 737. http://dx.doi.org/10.3390/membranes11100737.

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To construct a novel artificial cornea biomaterial, a method to prepare collagen lamellar matrix was developed in this study using grass carp scales as raw materials. The relationship between the structure of fish scale collagen lamellar matrix and the optical and mechanical properties was analyzed, and co-culture of it and rat bone marrow mesenchymal stem cells (BMSCs) was performed to preliminarily analyze the cellular compatibility of fish scale collagen lamellar matrix. The results show that the grass carp scales could be divided into base region, lateral region and parietal region accordi

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Gopalakrishnan, Gopakumar, William E. Blevins, and William G. Van Alstine. "Osteocartilaginous Metaplasia in the Right Atrial Myocardium of Healthy Adult Sheep." Journal of Veterinary Diagnostic Investigation 19, no. 5 (2007): 518–24. http://dx.doi.org/10.1177/104063870701900509.

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Among 172 hearts from clinically normal adult sheep aged 1.5 to 7 years evaluated for the presence of cartilage and/or bone in the right atrial myocardium, 3.49% (6/172) had palpable evidence of osteocartilaginous foci. An additional 8% prevalence was estimated based on radiographs of hearts that contained ≤1 mm foci of nonpalpable, radiographically dense bone. Microscopically, the nodules in the atria were characterized by mature lamellar bone enclosing adipose tissue, with occasional new bone formation by endochondral ossification. No degenerative changes were evident in the affected atrial

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Aliyev, Ali, Ömer Ekin, Ozan Bitik, et al. "A Novel Method of Neo-osseous Flap Prefabrication: Induction of Free Calvarial Periosteum with Bioactive Glass." Journal of Reconstructive Microsurgery 34, no. 05 (2017): 307–14. http://dx.doi.org/10.1055/s-0037-1598254.

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Background Reconstruction of craniofacial bone defects is a primary focus of craniofacial surgery. Although autogenous bone grafts remain as the gold standard, alloplastic materials have also gained widespread popularity due to their off-the-shelf availability, ease of use, and durability. In addition to replacing the missing bone, some of these alloplastic materials have also been found to induce new bone formation. Objectives In this study, the phenomenon of neo-osseous induction with bioactive glass was investigated for different implant-soft tissue configurations. Materials and Methods Thi

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Cerrito, Paola, Bin Hu, Justin Z. Goldstein, Rachel Kalisher, Shara E. Bailey, and Timothy G. Bromage. "Elemental composition of primary lamellar bone differs between parous and nulliparous rhesus macaque females." PLOS ONE 17, no. 11 (2022): e0276866. http://dx.doi.org/10.1371/journal.pone.0276866.

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Extracting life history information from mineralized hard tissues of extant and extinct species is an ongoing challenge in evolutionary and conservation studies. Primary lamellar bone is a mineralized tissue with multidien periodicity that begins deposition prenatally and continues until adulthood albeit with concurrent resorption, thus maintaining a record spanning several years of an individual’s life. Here, we use field-emission scanning electron microscopy and energy-dispersive X-ray analysis to measure the relative concentrations of calcium, phosphorous, oxygen, magnesium and sodium in th

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Рогожников, Алексей, and A. Rogoznikov. "RESULTS OF THE PILOT STUDIES DIRECTED ON THE ASSESSMENT OF BIOLOGICAL PROPERTIES OF THE MODIFIED ZIRCONIUM DIOXIDE GRANULES." Actual problems in dentistry 11, no. 3 (2015): 49–56. http://dx.doi.org/10.18481/2077-7566-2015-11-3-4-49-56.

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Materials for production of dentures and implantation systems have to possess a complex of characteristics among which lack of toxicity in relation to tissues of the patient and bioinertness is obligatory. The purpose of work was development of ceramics on the basis of zirconium dioxide with a further assessment of parameters of acute toxicity, and also research of influence on regeneration of a bone tissue. For the solution of objectives the ceramics on the basis of zirconium dioxide stabilized the 15th pier was developed and received. % cerium dioxide. By results of experiment of an assessme

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Gorustovich, A., M. B. Guglielmotti, J. M. Porto López, and R. L. Cabrini. "Increased Osteogenesis Elicited by Boron-Modified Bioactive Glass Particles in the SiO₂-CaO-P₂O₅-Na₂O System: A Histomorphometric Study in Rats." Key Engineering Materials 284-286 (April 2005): 913–16. http://dx.doi.org/10.4028/www.scientific.net/kem.284-286.913.

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The effect of boron-containing bioactive glass (BG) particles in the SiO2-CaO-P2O5-Na2O system on the bone formation was studied by histologic, histomorphometric and microchemical evaluation. Wistar rats were used throughout. Under anesthesia, 45S5 BG particles were placed inside the medullary compartment of the tibia (Control), while in the contralateral tibia (Experimental) 45S5.2B BG particles were implanted. The animals were sacrificed 15 days postimplantation. The tibiae were resected, radiographed, and embedded in methyl methacrylate resin. Sections were stained with toluidine blue and a

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Peltola, Matti, Kalle Aitasalo, Teemu Tirri, Jami Rekola, and A. Puntala. "Long-Term Tissue Reactions of Three Biomaterials in Craniofacial Surgery." Key Engineering Materials 361-363 (November 2007): 1343–46. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.1343.

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Successful craniofacial reconstruction needs both a well-known and a reliable reconstruction material. However, there is often a lack of long-term knowledge of the tissue reactions and healing process in the human body. In this study, frontal sinus obliterations with bovine bone natural hydroxyapatite derivative (BHA), synthetic bioactive glass S53P4 (BAG) and hydroxyapatite cement (HAC) were investigated with clinical, histologic, scanning electron microscopic (SEM) and energy dispersive x-ray analysis (EDXA) 27, 12 and 3 years postoperatively. The aim was to determine the long-term clinical

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Musleh, Alaa, Zainab Hashim, and Haider Jaafar. "Effect of 8-Week Exercise Program on Bone Biomarker Osteocalcin and Bone Histomorphometry Features in Male Rats." Iraqi Journal of Medical Sciences 18, no. 2 (2020): 145–54. http://dx.doi.org/10.22578/ijms.18.2.9.

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Background: The anabolic effect of physical exercise on osseous tissue is related to mechanical effort, leading to the osteogenic response by causing dynamic changes, which stimulate osteocytes through fluid shifts in their canalicular network. They produce signaling molecules that regulate bone formation and absorption by osteoblast and osteoclasts. Objective: To study the effect of 8-week exercise training programs on the histomorphometry of male rat femur bone including weight, length, thickness and the bone formation biomarker (osteocalcin). Methods: The study was done in the labs of Colle

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Nadyrov, E. A., V. I. Nikolaev, S. I. Kirilenko, et al. "Morphological and radiological characteristics of experimental bone tissue regeneration." Health and Ecology Issues, no. 3 (October 1, 2021): 94–104. http://dx.doi.org/10.51523/2708-6011.2021-18-3-12.

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Objective. To study the dynamics of reparative bone tissue regeneration in experimental animals using a native transplantation autosmix (NTA).Materials and methods. Male Wistar rats weighing 180–200 g and aged 6–7 months were used. Bone tissue defects were modelled using a cutter with a diameter of 2 mm (experimental group). A similar defect of the middle third of the right tibia was formed in the control group animals without flling the defects with bone tissue. The animals were removed from the experiment on days 3, 7, 14, 30 and 60 of the experiment (per 6 animals for each observation perio

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Wawrzyniak, Agata, and Krzysztof Balawender. "Structural and Metabolic Changes in Bone." Animals 12, no. 15 (2022): 1946. http://dx.doi.org/10.3390/ani12151946.

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As an essential component of the skeleton, bone tissue provides solid support for the body and protects vital organs. Bone tissue is a reservoir of calcium, phosphate, and other ions that can be released or stored in a controlled manner to provide constant concentration in body fluids. Normally, bone development or osteogenesis occurs through two ossification processes (intra-articular and intra-chondral), but the first produces woven bone, which is quickly replaced by stronger lamellar bone. Contrary to commonly held misconceptions, bone is a relatively dynamic organ that undergoes significan

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Huseynov, Agil N., Vladislav A. Malanchuk, Mykhailo S. Myroshnychenko, and Olga V. Zaytseva. "EXPERIMENTAL AND MORPHOLOGICAL ASSESSMENT OF THE INFLUENCE OF HYDROXYAPATITE-CONTAINING OSTEOTROPIC MATERIAL AND ELECTRICAL STIMULATION ON REPARATIVE OSTEOGENESIS OF THE LOWER JAW." Polski Merkuriusz Lekarski 51, no. 4 (2023): 358–66. http://dx.doi.org/10.36740/merkur202304110.

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Aim: The aim of the study was to reveal the peculiarities of reparative osteogenesis in experimental lower jaw defect under the conditions of hydroxyapatite-containing osteotropic material application and electrical stimulation. Materials and Methods: An experiment was conducted on 48 mature male rats of the WAG population. All animals were divided into 4 groups (12 animals in each group). Group 1 included rats that were not subjected to any manipulations. Group 2 included rats that were modeled with a perforated defect of the lower jaw body. Group 3 included rats that were modeled with a perf

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Boiko, Andrii A., Vladislav A. Malanchuk, and Mykhailo S. Myroshnychenko. "Reparative osteogenesis in mandible in cases of filling a bone defect with hydroxyapatite-containing osteotropic material and injecting the surrounding soft tissues with thymalin: experimental and morphological study." Wiadomości Lekarskie 77, no. 1 (2024): 68–76. http://dx.doi.org/10.36740/wlek202401110.

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Aim of the study was to identify the morphological features of reparative osteogenesis in the lower jaw bone of rats in cases of filling a bone defect with hydroxyapatite-containing osteotropic material (bone graft “Biomin GT”) and injecting the surrounding soft tissues with thymalin. Materials and Methods: An experiment was conducted on 48 mature rats of the WAG population weighing 160-180 grams which were divided into four groups. Group 1 included 12 rats with a simulated holey defect in the lower jaw. Group 2 included 12 rats with a simulated holey defect in the lower jaw followed by its cl

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Borkhunova, Elena N., Maria A. Kuznetsova, and Mikhail D. Kachalin. "Use of the MMSC secretome to stimulate reparative osteogenesis: an experimental study." Veterinariya, Zootekhniya i Biotekhnologiya 5, no. 126 (2024): 65–75. http://dx.doi.org/10.36871/vet.zoo.bio.202405007.

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The article is devoted to the study of the effect obtained by using a regenerative medicine drug (secretome of multipotent mesenchymal stromal cells) to stimulate reparative regeneration of a long tubular bone after a fracture. The presented materials are a fragment of comprehensive studies on the mechanisms of reparative regeneration of bone tissue under the conditions of the use of cellular products. The work was carried out on outbred white rats, in which the state of the bone regenerate was studied on the 30th and 120th days after injury. After the fracture, the animals were kept under nor

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Nikolić, Marija, Jelena Popović, Jovanka Gašić, and Radomir Barac. "The effect of zinc oxide based sealer on bone defects healing." Stomatoloski glasnik Srbije 63, no. 4 (2016): 159–66. http://dx.doi.org/10.1515/sdj-2016-0016.

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Summary Introduction Obturation as the final phase of endodontic treatment aims to provide complete hermetic filling along the entire length of the canal system from the coronal opening to the apical end. The aim of this study was to evaluate histological response of bone tissue on the implantaton of zinc oxide based material in artificially prepared defect in the mandible of rats. Material and method For the experiment, sixteen male Wistar rats were used. Using sterile steel burs a defect was made in mandible, between the midline and mental foramen. Zinc oxide based sealer was implanted in th

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Tairov, Umar. "STUDY OF VASCULARIZATION AND REPARATIVE REGENERATION OF LAMELLAR BONE TISSUE WITH SIMULATED DEFECTS OF MAXILLA (experimental research)." Actual problems in dentistry 18, no. 3 (2022): 119–26. http://dx.doi.org/10.18481/2077-7566-2022-18-3-119-126.

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Subject. Regeneration is one of the most relevant problems of medicine and biology. As it was before and as it is now, the field of investigation, which is connected with regeneration exploring, is a range of heated debates. There is a direct correlation between regeneration of bones and local metabolism, mineralization and early vascularization, which supplies nourishment and oxygenation of cell structure of the regenerate. Owing to these factors, the bone has only its mechanic properties. This prerequisite has made a lot of investigators to pay attention for vascular-regeneration complex in

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Huseynov, Agil N., Vladislav A. Malanchuk, Mykhailo S. Myroshnychenko, Olena V. Markovska, and Liliia P. Sukharieva. "MORPHOLOGICAL CHARACTERISTICS OF REPARATIVE OSTEOGENESIS IN THE RATS LOWER JAW UNDER THE CONDITIONS OF USING ELECTRICAL STIMULATION." Polski Merkuriusz Lekarski 51, no. 6 (2023): 592–97. http://dx.doi.org/10.36740/merkur202306102.

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Aim: The purpose of the study was to identify the morphological features of reparative osteogenesis in the rats lower jaw under the conditions of using electrical stimulation. Materials and Methods: An experiment was conducted on 24 mature male rats of the WAG population. Two groups were formed. Group 1 included 12 rats that were modeled with a perforated defect of the lower jaw body. Group 2 included 12 animals that were modeled with a perforated defect similar to group 1. In animals, a microdevice for electrical action was implanted subcutaneously in the neck area on the side of the simulate

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Leenstra, Thomas S., Jaap C. Maltha, Anne Marie Kuijpers-Jagtman, and Paul H. M. Spauwen. "Wound Healing in Beagle Dogs after Palatal Repair without Denudation of Bone." Cleft Palate-Craniofacial Journal 32, no. 5 (1995): 363–70. http://dx.doi.org/10.1597/1545-1569_1995_032_0363_whibda_2.3.co_2.

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The connection of scar tissue to palatal bone by Sharpey's fibers, after cleft palate surgery, might lead to maxillary growth inhibition. The aim of this study, in beagle dogs, was to investigate the possibility of preventing the development of Sharpey's fibers by means of a modified surgical technique. In group 1, palatal repair according to von Langenbeck, was simulated. In group 2, palatal surgery was performed using a new partially split flap technique. The palates were histologically evaluated 12 weeks after surgery and compared with a control group. In group 1, the scar tissue was firmly

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Tasic, Desanka, Milorad Pavlovic, Dragan Stankovic, Irena Dimov, Goran Stanojevic, and Dragan Dimov. "Ossifying chondrolipoma of the tongue." Vojnosanitetski pregled 69, no. 11 (2012): 1009–12. http://dx.doi.org/10.2298/vsp1211009t.

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Introduction. Chondrolipomas and osteolipomas are uncommon variants of lipomatous tumors. Case report. We presented a 60-year-old woman with ossifying chondrolipoma of the tongue. Clinical examination revealed a firm nodular mass, located in the midline of the posterior region on the dorsal surface of the tongue. Histologically, the lesion was well-delimited showing areas of mature adipocytes arranged in lobules and separated by fibrous connective tissue septa, islands of mature cartilaginous tissue and osseous metaplasia. Trabeculae of lamellar bone within a fibro-fatty background were visibl

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Korenkov, O. "Regeneration of experimental long bone defect after implantation in its cavity of osteoplastic material “Calc-i-oss®”." Journal of Morphological Sciences 33, no. 02 (2016): 099–102. http://dx.doi.org/10.4322/jms.090215.

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Abstract Introduction: There is a significant divergence of data on the rate of resorption and replacement by the bone tissue of osteoplastic materials based on β-tricalcium phosphate in cancellous bone. At the same time in literature missing morphometric and electron microscopic features of bone tissue of the regenerate of compact substance of bone in these conditions. This study was aimed at the assessment of the healing of compact bone tissue defect after implantation of osteoplastic material “Calc-i-oss®” with the definition of the dynamics of resorption and morphological characteristics o

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Reshetnyak, V. V., V. V. Burdeyniy, V. V. Pronin, and Ye A. Iskaliev. "Reparative histogenesis of bone tissue in femoral fractures in rats using biocomposite material along with immunocorrection." Veterinary Science Today, no. 3 (August 17, 2021): 248–53. http://dx.doi.org/10.29326/2304-196x-2021-3-38-248-253.

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The paper studies the effect of the RVI biocomposite material belonging to the group of osteoplastic biocomposite materials, the RV-2 immunomodulator – a synthetic dipeptide inducing an immunocorrective effect, and combinations of these drugs on the reparative histogenesis of bone tissue in femoral fractures in rats. It was found that the remodeling of the primary bone callus into the secondary one in the fracture of the studied animals was of a diverse nature. This process was the most pronounced in the group where the components were used in complex, i.e. the bone defect was filled with RVI

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LECUONA, Agustina, Julia Brenda DESOJO, and Ignacio Alejandro CERDA. "New information on the anatomy and histology of Gracilisuchus stipanicicorum (Archosauria: Pseudosuchia) from the Chañares Formation (early Carnian), Argentina." Comptes Rendus Palevol 19, no. 3 (2020): 40–62. https://doi.org/10.5852/cr-palevol2020v19a3.

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<em>Gracilisuchus stipanicicorum</em> Romer, 1972 is a basal suchian from the Late Triassic Chañares Formation (Argentina), nested in the recently erected Gracilisuchidae, along with <em>Turfanosuchus dabanensis</em> Young, 1973 and <em>Yonghesuchus sangbiensis</em> Wu<em> et al., </em>2001 from China. The six known specimens of <em>Gracilisuchus</em> Romer, 1972 preserve most of the skeleton, lacking only most of the shoulder girdle and forelimb. Our latest fieldwork has recovered two specimens that preserve previously unknown elements, including the humerus, radius, and ulna, as

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Riabenko, Таtiana V., Oleksii V. Korenkov, Serhii M. Dmytruk, et al. "MORPHOLOGICAL FEATURES OF TUBULAR BONES REPARATIVE REGENERATION UNDER THE INFLUENCE OF ANTITUMOR CHEMOTHERAPEUTICS." Wiadomości Lekarskie 75, no. 3 (2022): 570–76. http://dx.doi.org/10.36740/wlek202203102.

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The aim: Determination of morphological features of reparative regeneration of diaphysis defect of long tubular bones under the influence of antitumor chemotherapeutics in a model experiment. Materials and methods: 96 white nonlinear rats after application of the perforated defect of the femur were administered the appropriate antitumor drug (doxorubicin, 5-fluorouracil, methotrexate) three times with an interval of 21 days. Morphological features of bone tissue formation and remodeling in the regenerate area were studied using histological and morphometric methods. Results: The inhibitory eff

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