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1

Dr., Somi Ahmed*, Atul Maharjan Dr., Bishal Maharjan Dr., Tauqeer Alam Ansari Dr., and Aditya Yadav Dr. "DONISLECEL (LANTIDRA) FOR BRITTLE TYPE 1 DIABETES MELLITUS - A NARRATIVE REVIEW." World Journal of Pharmaceutical Science and Research 3, no. 4 (2024): 316–25. https://doi.org/10.5281/zenodo.13625575.

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Donislecel (Lantidra) is an excellent stem cell therapy currently in use for the management of brittle type 1 diabetes mellitus. We explored the evolving landscape of Type 1 Diabetes treatment, focusing on Donislecel (Lantidra), the first FDA-approved allogeneic cellular therapy.  Integrating innovative therapies like Donislecel with existing treatment options can lay the foundation for enhancing the standard of life for individuals with Type 1 Diabetes. We analyzed four databases, namely Pubmed, Science Direct, Researchgate, and Google Scholar by searching the following keywords: (&
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Mozhyna, T. L., and Н. V. Belyaeva. "The realities of modern cell therapy: obtaining and transplanting pancreatic cells." Herald of Pancreatic Club 66, no. 1 (2025): 62–70. https://doi.org/10.33149/vkp.2025.01.04.

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Diabetes mellitus (DM) is recognized as a serious challenge for the global healthcare system due to the rapid increase in its prevalence, DM-associated morbidity, disability, and mortality. The mainstay of treatment for type 1 diabetes is the administration of exogenous insulin. Therefore, recent research has focused on cell therapy, which involves administering autologous (own cells) or allogeneic (donor) cellular material to patients. Cell therapy for diabetes involves using stem (mesenchymal, embryonic) and non-stem (bone marrow cells) cells, which helps restore immune tolerance and preserv
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Cuéllar Rodríguez, Santiago. "Novel Drugs Recently Authorized by EMA and FDA (Q3, 2023)." Anales de la Real Academia Nacional de Farmacia 89, no. 89(03) (2023): 395–406. http://dx.doi.org/10.53519/analesranf.2023.89.03.11.

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EMA (EUROPEAN MEDICINES AGENCY): (A) TRACTO ALIMENTARIO Y METABOLISMO: Diabetes mellitus tipo 1: Donislecel (Lantidra®; FDA). Enfermedad CHAPLE: Pozelimab (Veopoz®; FDA). (D) DERMATOLOGÍA: Blefaritis por Demodex: Lotilaner (Xdemvy®; FDA). (J) ANTIINFECCIOSOS SISTÉMICOS: Ántrax: Vacuna Ántrax (Cyfendus®; FDA). (L) AGENTES ANTINEOPLÁSICOS E INMUNOMODULADORES: Cáncer de esófago: Tislelizumab (Tevimbra®; EMA). Leucemia mieloide aguda: Quizartinib (Vanflyta®; FDA). Mieloma múltiple: Talquetamab (Talvey®; EMA/FDA) y Elranatamab (Elrexfio®; FDA). Mielofibrosis: Momelotinib (Ojjaara®; FDA).Miastenia g
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Munawaroh, Siti, and Sri Yuni Wulandari. "Analisis Strategi Penanganan Keluhan dan Kepuasan Konsumen pada Toko Lantikya Store Jombang." Bisman (Bisnis dan Manajemen): The Journal of Business and Management 6, no. 2 (2023): 409–18. http://dx.doi.org/10.36815/bisman.v6i2.2799.

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Complaint is a feedback or feedback given by consumers for the service they have received. Complaints given by consumers usually arise from dissatisfaction with the services provided by company or agency employees. Satisfaction is someone's pleasure or disappointment that occurs after a comparison of product performance is set based on expected performance. Lantikya store is a store engaged in the sale of office stationery items (ATK), galleries, accessories, baby shops, children's toys, and many more. Lantikya Store often finds consumer complaints in the form of unsatisfactory service and emp
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Fatmawati, Heni Nurlia, and Wisnu Mahendri. "Descriptive Analysis of Brand Loyalty, Reputation, and Equity at Lantikya Store." INCOME: Innovation of Economics and Management 4, no. 3 (2025): 112–17. https://doi.org/10.32764/income.v4i3.6008.

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This study aims to quantitatively describe the profile of customer loyalty, brand reputation, and brand equity at Lantikya Store Jombang. Amidst fierce competition in the retail business, a deep understanding of the actual condition of these key marketing variables is essential for formulating effective strategies. Using a descriptive research design with a quantitative approach, data was collected through questionnaires from 110 Lantikya Store customers selected using a probability sampling technique. Data analysis focused on descriptive statistics, including frequency, percentage, and mean v
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Viti, Robert M. "Etienne Lantier and family: Two-timing inL'Assommoir andGerminal." Neophilologus 75, no. 2 (1991): 200–206. http://dx.doi.org/10.1007/pl00020479.

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Viti, Robert M. "Etienne Lantier and family: Two-timing inL'Assommoir andGerminal." Neophilologus 75, no. 2 (1991): 200–206. http://dx.doi.org/10.1007/bf02398473.

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Victoriano, Arturo. "La reestructuración del conservadurismo victoriano: a propósito del ocaso de la nación dominicana." Revista ECOS UASD 11, no. 9 (2003): 179–82. http://dx.doi.org/10.51274/ecos.v11i9.pp179-182.

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El pensamiento conservador dominicano tiene una continuidad, se pueden trazar sus líneas y se puede seguir su devenir histórico. Desde el ataque de Bobadilla y Santana a la empresa liberal duartiana hasta nuestros días de reivindicación de Joaquín Balaguer y su doctrina política. Dentro de estas líneas, la vertiente histórica ha sido de primordial. El nuestro es un pueblo que gusta de la historia (cada año el inefable José Rafael Lantigua registra los libros dominicanos más vendidos y los de historia suelen estar a la cabeza, pero ese afán del escaso público lector dominicano por la historia,
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Ziyamukhamedova, Shahnoza. ""CONSIDERATIONS ON THE STUDY OF THE AFFIXES -LAN, -LASH, -LAT, -LANTIR, -LASHTIR USED IN THE NEW CONSTITUTION OF UZBEKISTAN IN LEGAL EDUCATION "." Jurisprudence 5, no. 1 (2025): 129–35. https://doi.org/10.51788/tsul.jurisprudence.5.1./lufn6495.

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"The article examines issues related to homonymy in compound affixes and affix systems in the Uzbek language, analyzing their grouping, semantic relations, and semantic-structural features. Special attention is also paid to the issues of systematization and ordering of homoaffixes. In the study, the new Constitution of Uzbekistan was studied from a linguistic point of view, and the use of homoaffixes, in particular, the affixes -lan, -lash, -lat, -lantir, and -lashtir in legal education was investigated. The verb is distinguished by its complexity and controversial aspects. Therefore, linguist
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Silva, Felipe Santana e., Gerllany Silva e. Silva, Ana Carla Marques da Costa, Francidalma Soares Sousa Carvalho Filha, Francisco Cesino de ]Medeiros Júnior, and Joseneide Teixeira Câmara. "Cuidados de enfermagem a pacientes oncológicos: revisão integrativa." Research, Society and Development 8, no. 6 (2019): e35861037. http://dx.doi.org/10.33448/rsd-v8i6.1037.

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Objetivo: identificar os cuidados de enfermagem à pacientes oncológicos. Metodologia: estudo do tipo revisão integrativa, utilizou-se dos seguintes descritores: enfermagem oncológica, oncologia, cuidados de enfermagem para busca dos artigos, as bases de dados selecionadas foram: Scientific Electronic Library Online (SciELO), Biblioteca Virtual em Saúde (BVS), Sistema Regional de Informação em Linha para Revistas Científicas da América Latina, Caribe, Espanha e Portugal (LANTIDEX). Resultados: após análise dos dados afirma-se que os principais tipos de cuidados de enfermagem são: realização do
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Litvak, Lily. "La Colina de los cipreses." SIGLO DIECINUEVE (Literatura hispánica), no. 21 (April 9, 2015): 213–47. http://dx.doi.org/10.37677/sigloxix.vi21.76.

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Durante el fin del siglo XIX se otorgó gran importancia al conocimiento del arte. Los escritores del cambio del siglo XIX al XX exhibían su cultura a través de sus obras literarias, comolo hace por ejemplo Rubén Darío en las “transposiciones pictóricas” que incluyó en la sección titulada “En Chile” de Azul. También ilustran ese interés las numerosas novelas donde el protagonista es un artista; Émile Zola personificó a Cézanne como Claude Lantier en l’Oeuvre, Sorolla se perfila en el Renovales de La maja desnuda de Blasco Ibáñez, Gustave Moreau había encarnado en numerosos personajes en Jean Sa
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Jones, Nathan P., Irina Chindea, Daniel Weisz Argomedo, and John Sullivan. "A Social Network Analysis of Mexico’s Dark Network Alliance Structure." Journal of Strategic Security 15, no. 4 (2022): 76–105. http://dx.doi.org/10.5038/1944-0472.15.4.2046.

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This article assesses Mexico’s organized crime alliance and subgroup network structures. Through social network analysis (SNA) of data from Lantia Consultores, a consulting firm in Mexico that specializes in the analysis of public policies, it demonstrates differential alliance structures within Mexico’s bipolar illicit network system. The Cártel de Jalisco Nueva Generación’s (CJNG) alliance structure is top-down and hierarchical, while the Sinaloa Cartel is denser, particularly in the broader Tierra Caliente region. Additionally, our analysis found a sparse overall network with many isolates
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Morel, Pierre. "À propos de Germinal d'Émile Zola: le personnage d'Étienne Lantier et la représentation du leader." Les Lettres Romanes 43, no. 3 (1989): 187–94. http://dx.doi.org/10.1484/j.llr.4.00445.

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Cuvardic García, Dorde. "El topos simbolista de la ciudad muerta en la tradición literaria europea y española." Revista de Filología y Lingüística de la Universidad de Costa Rica 39, no. 2 (2014): 27. http://dx.doi.org/10.15517/rfl.v39i2.15011.

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En este artículo se realiza un exhaustivo recorrido por la representación de la ciudad muerta en la literatura europea y española fin de siglo, con especial interés en Rodenbach, en el caso belga, y en Azorín, en el español. Primero, se emprende una introducción por este topos, por el estado la cuestión crítico existente y por las razones de su eclosión en la literatura europea fin de siglo. En segundo lugar, se identifican las más importantes manifestaciones de este topos en la literatura europea, con especial incidencia en Brujas la muerta (1892), de Georges Rodenbach, que inició su auge en
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Pasquel Tibán, Marjorie Micaela. "La danza andina y la expresión corporal en jóvenes adultos." MENTOR revista de investigación educativa y deportiva 4, no. 10 (2024): 775–94. https://doi.org/10.56200/mried.v4i10.9181.

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La danza andina fue valorada como pieza fundamental para la vida espiritual, social y cultural, que juega un papel fundamental como una herramienta para comunicar emociones y conectar con la cosmovisión andina, esta práctica fue perdiendo interés entre los jóvenes adultos, poniendo en riesgo su patrimonio cultural. El objetivo de esta investigación fue el análisis de los postulados teóricos sobre los autores que brinda la danza andina en el trabajo de la expresión corporal para promover su práctica y valoración. La metodología que se utilizo fue una revisión sistemática de 23 fuentes bibliográ
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Медведь, А. Н. "WOOD AND EARTH FORTIFICATIONS IN 16th-CENTURY ITALY -ESTABLISHMENT OF THE TRADITION)." Краткие сообщения Института археологии (КСИА), no. 267 (October 4, 2022): 396–409. http://dx.doi.org/10.25681/iaras.0130-2620.267.396-409.

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Статья посвящена истории развития древо-земляной фортификации в Европе второй половины XVI в. Рассматриваются два трактата, посвященные созданию древо-земляных укреплений, - Дж. Лантьери «Duo libri del modo di fare le fortificazioni di terra» (1550-е гг.) и Г. Галилея «Breve Instruzione all’architettura militare» (1590-е гг.). Анализируются особенности создания укреплений, изложенные в этих трактатах, сравниваются технологические приемы, описанные авторами. Проводится сравнение с более ранними итальянскими произведениями на аналогичную тематику. Делается вывод о том, что во второй половине XVI
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Mohamed, Mouafik, Ninich Oumaima, Ouajdi Mohamed, Aoujdad Jalila, El Antry Salwa, and El Aboudi Ahmed. "Ecophysiology of Four Mediterranean Forest Species." Annals of Biomedical Science and Engineering 7, no. 1 (2023): 064–68. http://dx.doi.org/10.29328/journal.abse.1001026.

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Forеst dеgradation has bеcomе incrеasingly pronouncеd in rеcеnt timеs due to shifts in climatе pattеrns and prolongеd drought pеriods. This invеstigation aims to cultivatе high-quality vеgеtation and gain insights into thеir еcophysiological rеsponsеs undеr conditions of watеr strеss. Spеcifically, wе conductеd еxpеrimеnts on 6-month-old individuals from two dеciduous spеciеs (Quеrcus subеr and Cеratonia siliqua) and two conifеrs (Tеtraclinis articulata and Cеdrus at-lantica), subjеcting thеm to watеr strеss conditions. Wе mеasurеd and analyzеd both thе basic (Ψb) and minimum (Ψm) lеaf watеr p
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18

Jones, Edward Corredera. "David M. Lantigua, Infidels and Empires in a New World Order: Early Modern Spanish Contributions to International Legal Thought." Grotiana 43, no. 1 (2022): 301–5. http://dx.doi.org/10.1163/18760759-43010016.

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Núñez-Troconis, José. "Papel del virus del papiloma humano en el desarrollo del cáncer del cuello uterino." Investigación Clínica 64, no. 2 (2023): 233–54. http://dx.doi.org/10.54817/ic.v64n2a09.

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Abstract. The present narrative review was conducted to investigate and to compile information about the physiopathology of the Human Papilloma Virus (HPV) and the viral mechanisms of infection of the host’s cells, as well as how the virus survives the host’s innate immunological mechanisms and the mechanisms to produce cervical benign and malignant lesions. Literature searches were performed electronically in PubMed, Medline, ISI, DOAJ, Spring-er, Embase. Web of Knowledge, DOAJ, y Google Scholar, Hinari, JAMA Network, Oxford Academic and Research Life for original articles written in English
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Canning, Joseph. "Infidels and Empires in a New World Order: Early Modern Spanish Contributions to International Legal Thought by David M. Lantigua (review)." Thomist: A Speculative Quarterly Review 87, no. 3 (2023): 510–14. http://dx.doi.org/10.1353/tho.2023.a900235.

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Núñez-Troconis, José, Daniel Carvallo, and Elizabeth Martínez-Núñez. "Primary Dysmenorrhea: pathophysiology." Investigación Clínica 62, no. 4 (2021): 378–406. http://dx.doi.org/10.22209/ic.v62n4a08.

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The present study was conducted to investigate and analyze the recent and relevant studies about primary dysmenorrhea and its pathophysiology. Literature searches were performed electronically in PubMed, Medline, ISI, DOAJ, Springer, Embase. Web of Knowledge, DOAJ, Google Scholar and the Cochrane Library for original articles written in English and in Scielo, Lantidex, Imbiomed-L, Redalyc and Google Scholar for original articles written in Spanish. The searches included the key words (Mesh): menstruation, menstrual period, menstrual cycle, dysmenorrhea, primary dysmenorrhea, inflammatory subst
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Tenório, Fernando Guilherme. "Administração e a questão social: entre o “robinsonismo” e o “étiennismo”." Organizações & Sociedade 23, no. 78 (2016): 460–86. http://dx.doi.org/10.1590/1984-92307867.

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Resumo Nas últimas décadas de hegemonia liberal econômica ou, como alguns desejam denominar, neoliberal, o determinismo de mercado se sobressai à sociedade. Tal leitura de mundo – o mercado não como um enclave da sociedade, mas desejando substituí-la – tem influenciado, sobremaneira, as instituições de ensino superior (IES), notadamente aquelas dedicadas às ciências sociais aplicadas, como é o caso da Administração. Desejando sair do marasmo predominante nos textos acadêmicos, recorremos à estética desde os romances Robinson Crusoé e Germinal, para inferir que as teses centrais dessas ficções
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O’Donovan, Oliver. "Book Review: Infidels and Empires in a New World Order: Early Modern Spanish Contributions to International Legal Thought by David M. Lantigua." Studies in Christian Ethics 35, no. 2 (2022): 397–401. http://dx.doi.org/10.1177/09539468221080656l.

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Betancourth, López Cristhian Fernando, Cruz Patricia Millán, and de Stouvenel Aida Rodríguez. "Caracterización de Plukenetia volubilis (sacha inchi) como alimento funcional en comparación con otras semillas oleaginosas tradicionales." Business Innova Sciences 5, no. 2 (2024): 64–87. https://doi.org/10.5281/zenodo.13750050.

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El Plukenetia volubilis L., conocido como sacha inchi, es una planta amazónica originaria de Perú que florece y fructifica continuamente semillas oleaginosas con alto contenido en ácidos grasos poliinsaturados con las cuales se produce aceite vegetal. Este contiene ácidos grasos monoinsaturados (omega-9) y poliinsaturados (omega-6), así como pequeñas cantidades de omega-3 en comparación con otros cultivos oleaginosos. El objetivo fue caracterizar el Plukenetia volubilis (sacha inchi) como alimento funcional en comparación con otras semill
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Lantika, Suci, Sulaiman Juned, and Sahrul Nazar. "PENCIPTAAN TEATER MERETAS ADAB BERANGKAT DARI TRADISI MELANGUN SUKU ANAK DALAM." Gorga : Jurnal Seni Rupa 10, no. 2 (2021): 268. http://dx.doi.org/10.24114/gr.v10i2.27137.

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The work of Meretas Adab is an achievement of the process of creating a theater based on research on the tradition of Melangun from Anak Dalam tribe. The form approach chosen in this creation process is a contemporary theatrical form. The formulation of the problem in question from this creation is how to realize the creation of a contemporary theater of Meretas Adab departing from the Melangun tradition. The theories used are contemporary theater theory, proscenium stage conventions and cultural arts exploration. The directing method used consisted of research, script preparation, selecting a
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Lévy, Ghyslain. "Éthique, inconscient et questions contemporaines , Monique Lauret (sous la direction de), avec textes de J. Cabassut, S. Camacho, B. Dollé-Monglond, D.-R. Dufour, M. Lantier, M. Lauret, J. Rouzel, M.-J. Sauret, M. Vaquié, L’Harmattan, 2022." Le Coq-héron N° 258, no. 3 (2024): 154–57. http://dx.doi.org/10.3917/cohe.258.0154.

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RIOS, PETER, JAMES J. MCGARRIGLE, GIOVANNA LAMONICA, et al. "35-OR: Lantidra, First FDA-Approved Cellular Therapy to Treat Type 1 Diabetes." Diabetes 73, Supplement_1 (2024). http://dx.doi.org/10.2337/db24-35-or.

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Despite intensive insulin therapy and frequent blood sugar monitoring, a subset of patients with type 1 diabetes (T1D) still suffer from debilitating symptoms, including severe hypoglycemia and hypoglycemia unawareness, and are left susceptible to the secondary complications of T1D. For T1D patients unable to achieve target hemoglobin A1c (HbA1c) despite intensive diabetes management and education, Lantidra is a treatment option to restore glycemic control, eliminate hypoglycemia episodes, and reduce or eliminate exogenous insulin injections. Lantidra is an FDA-approved allogeneic cellular the
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B. Bharambe, Shital, and Shailesh Jawarkar. "Lantidra: Cell Therapy for Treatment of Type 1 Diabetes Mellitus." Asian Journal of Pharmaceutical Research, September 20, 2024, 331–35. http://dx.doi.org/10.52711/2231-5691.2024.00052.

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The more recent cell treatment for type 1 Diabetes is called lantidra. Lantidra has recently received approval to treat type 1 Diabetes mellitus. The first allogeneic (deceased donor) pancreatic islet cell therapy, lantidra (donislecel), was approved by the FDA Centre for Biologics Evaluation and Research (CBER) on June 28, 2023. It is intended to treat adults with type 1 diabetes who, despite current management, do not achieve target glycosylated hemoglobin levels due to recurrent episodes of severe hypoglycemia. The editorial’s goal is to draw attention to the growing impact of type 1 diabet
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"Donislecel (Lantidra) for Type 1 Diabetes." Medical Letter on Drugs and Therapeutics 66, no. 1700 (2024): 63–64. http://dx.doi.org/10.58347/tml.2024.1700d.

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The FDA has approved donislecel-jujn (Lantidra – CellTrans), an allogeneic pancreatic islet cellular therapy, for use in conjunction with immunosuppression for treatment of adults with type 1 diabetes who are unable to approach target HbA1c because of current repeated episodes of severe hypoglycemia despite intensive diabetes management and education. Donislecel is the first cell-based treatment to be approved in the US for type 1 diabetes.
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Mbaye, El Hadji Arona, Evan A. Scott, and Jacqueline A. Burke. "From Edmonton to Lantidra and beyond: immunoengineering islet transplantation to cure type 1 diabetes." Frontiers in Transplantation 4 (March 20, 2025). https://doi.org/10.3389/frtra.2025.1514956.

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Type 1 diabetes (T1D) is characterized by the autoimmune destruction of insulin-producing β cells within pancreatic islets, the specialized endocrine cell clusters of the pancreas. Islet transplantation has emerged as a β cell replacement therapy, involving the infusion of cadaveric islets into a patient's liver through the portal vein. This procedure offers individuals with T1D the potential to restore glucose control, reducing or even eliminating the need for exogenous insulin therapy. However, it does not address the underlying autoimmune condition responsible for T1D. The need for systemic
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Wang, Yong, James McGarrigle, Jenny Cook, et al. "The future of islet transplantation beyond the BLA approval: challenges and opportunities." Frontiers in Transplantation 4 (March 7, 2025). https://doi.org/10.3389/frtra.2025.1522409.

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This opinion paper explores the path forward for islet transplantation as a cell therapy for type 1 diabetes, following the Biologics License Application (BLA) approval. The authors review key challenges and opportunities that lie ahead. After a brief overview of the history of human islet transplantation, the paper examines the FDA's regulatory stance on isolated islet cells and the requirements for obtaining a BLA. The authors discuss the significance of this approval and the critical steps necessary to broaden patient access, such as scaling up production, clinical integration, reimbursemen
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Ajmal, Nida, Maislin C. Bogart, Palwasha Khan, Ibiagbani M. Max-Harry, Amber M. Healy, and Craig S. Nunemaker. "Identifying Promising Immunomodulators for Type 1 Diabetes (T1D) and Islet Transplantation." Journal of Diabetes Research 2024, no. 1 (2024). https://doi.org/10.1155/jdr/5151171.

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Type 1 diabetes (T1D) is an autoimmune chronic disorder that damages beta cells in the pancreatic islets of Langerhans and results in hyperglycemia due to the loss of insulin. Exogenous insulin therapy can save lives but does not stop disease progression. Thus, an effective therapy may require beta cell restoration and suppression of the autoimmune response. However, currently, there are no treatment options available that can reverse T1D. Within the National Clinical Trial (NCT) database, a majority of over 3000 trials to treat T1D are devoted to insulin therapy. This review focuses on nonins
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Iqbal, Amna, and Ayesha Sheikh. "Donislecel (Lantidra); first stem cell therapy, a cutting-edge therapeutic option for type 1 diabetes, but would it be beneficial in the riskiest region of the world?" International Journal of Surgery: Global Health 6, no. 5 (2023). http://dx.doi.org/10.1097/gh9.0000000000000259.

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Rodrigues Júnior, Oswaldo Martins. "O Uso de Prótese Peniana Maleável no Tratamento da Disfunção Erétil." Revista Brasileira de Sexualidade Humana 1, no. 1 (2021). http://dx.doi.org/10.35919/rbsh.v1i1.927.

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KRAUSS, D. J.; LANTIGA, L. J.; CAREY, M. P.; MEISLER, A. W.; KELLY, C. M. O uso de prótese peniana maleável no tratamento da disfunção erétil: um estudo prospectivo do ajustamento pós-operatório. The Journal of Urology 142: 988-91, 1989.
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"Author commentary on Marten A. Lantinga et al." Endoscopy 53, no. 02 (2021): v9. http://dx.doi.org/10.1055/a-1287-4904.

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Kaounas, Vasıleıos. "New records for the Mycobiota of Greece." Anatolian Journal of Botany, April 24, 2024. http://dx.doi.org/10.30616/ajb.1455074.

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The Arachnopeziza obtusipila Grelet, Chaetothiersia cupressicola Valencia, Van Vooren & M. Vega, Chondrogaster pachysporus Maire, Ciboria brunneorufa Bres., Kallistoskypha incarnata (Duvernoy & Maire) Pfister, Agnello, Lantieri & LoBuglio, Lambertella palmeri Raitv. & R. Galán, Perilachnea fallax M. Carbone, Valencia, Tello & Van Vooren and Perilachnea humarioides Valencia, M. Vega & Van Vooren, eight rare fungi, are reported for the first time in Greece. This paper provides the descriptions of the recorded collections, accompanied by images of their macroscopical and m
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Uhde, Jan. "La bête humaine DVD." Kinema: A Journal for Film and Audiovisual Media, April 10, 2006. http://dx.doi.org/10.15353/kinema.vi.1148.

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The phenomenal growth of the DVD medium is seen by many as an excellent opportunity to bring important films of the present and past to audiences worldwide. Among the anxiously awaited issues, long overdue, has been Jean Renoir's 1938 masterpiece La bête humaine, adopted from the eponymous novel by Emile Zola. Set in the closely-knit community of Le Havre's cheminots, or railwaymen, this major work of the French pre-war poetic realism focuses on the gentle engineer Lantier (Jean Gabin) and his tragic struggle with hereditary insanity. The past haunts other characters of the story as well, espe
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Kristanti, Beni Tiyas, Achmad Junaidi, and Eka Prakarsa Mandyartha. "IMPLEMENTASI K-MEANS CLUSTERING DALAM SEGMENTASI PELANGGAN BERDASARKAN USIA, PENDAPATAN, DAN MODEL RFM (STUDI KASUS: LANTIKYA STORE JOMBANG)." Jurnal Informatika dan Teknik Elektro Terapan 12, no. 3 (2024). http://dx.doi.org/10.23960/jitet.v12i3.4677.

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Lantikya Store Jombang merupakan salah satu toko retail di Kabupaten Jombang yang belum menerapkan strategi pemasaran yang memberikan pelayanan yang berbeda berdasarkan karakteristik dan tipe pelanggan. Segmentasi pelanggan adalah proses membagi pelanggan kedalam kelompok berdasarkan karakteristik atau perilaku yang berbeda untuk menunjukkan tingkat keragaman di antara pelanggan. Karakteristik dan perilaku pelanggan dilihat berdasarkan usia, pendapatan, rencency (terakhir melakukan transaksi), frequency (jumlah kedatangan), dan monetery (jumlah uang yang dikeluarkan) atau disebut dengan RFM (R
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Domingo, Rafael. "Rethinking the School of Salamanca." Journal of Law and Religion, July 4, 2022, 1–9. http://dx.doi.org/10.1017/jlr.2022.28.

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Abstract Reviewed: The School of Salamanca: A Case of Global Knowledge Production. Edited by Thomas Duve, José Luis Egío, and Christiane Birr. Leiden: Brill, 2021. Pp. 430. $172.00 (cloth); Open Access (digital). ISBN: 9789004449732. ¿Qué es la Escuela de Salamanca? [What is the School of Salamanca?] Edited by Simona Langella and Rafael Ramis-Barceló. Madrid, Porto: Sindéresis, 2021. Pp. 402. €30.00 (paper). ISBN: 9788418206610. A Companion to the Spanish Scholastics. Edited by Harald E. Braun, Erik De Bom, and Paolo Astorri. Leiden: Brill, 2022. Pp. 628. $275.00 (cloth); $283.00 (digital). IS
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DUCROT, C. "Chapitre 3 : Lutte contre les EST animales. Les moyens mis en oeuvre." INRAE Productions Animales 17, HS (2004). http://dx.doi.org/10.20870/productions-animales.2004.17.hs.3631.

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Les connaissances acquises sur les ESST au cours des années passées ouvrent des perspectives dans la lutte contre ces maladies, tant pour soigner les malades atteints de la Maladie de Creutzfeldt-Jakob que pour maîtriser et prévenir les risques liés à ces agents pour la population humaine et les espèces animales.La question du diagnostic des ESST animales au laboratoire est discutée dans l’article de Lantier et al., ainsi que les développements en cours pour permettre le diagnostic avant la mort et la distinction des souches d’ESST les unes des autres avec des outils biochimiques.
 L’arti
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Gluais Dagorn, Pascale, Bjoern Buchholz, Hester Bange, Laura Blockken, David E. Moller, and Sophie Hallakou-Bozec. "MO019: Preclinical Efficacy of Direct AMPK Activation with a Novel Small Molecule–PXL770–For the Treatment of Autosomal Dominant Polycystic Kidney Disease." Nephrology Dialysis Transplantation 37, Supplement_3 (2022). http://dx.doi.org/10.1093/ndt/gfac061.014.

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Abstract BACKGROUND AND AIMS Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease. It is caused by mutations in the PKD1 gene, and to a lesser extent PKD2. In this context, accumulating evidence has suggested a potential role of reduced AMP-activated protein kinase (AMPK) signaling in modulating cyst growth. We assessed the potential effects of PXL770, a clinical stage direct allosteric AMPK activator in conventional ADPKD models—3D cyst growth/swelling in vitro and efficacy in an ADPKD mouse model. METHOD In vitro, PXL770 (0.5–50 µM) was tested in 3
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