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Journal articles on the topic 'Large artery stiffness'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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1

Benetos, Athanase, Stéphane Laurent, Roland G. Asmar, and Patrick Lacolley. "Large artery stiffness in hypertension." Journal of Hypertension 15 (1997): S89—S97. http://dx.doi.org/10.1097/00004872-199715022-00009.

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2

Mitchell, Gary F. "Proteomics of Large Artery Stiffness." JACC: Basic to Translational Science 9, no. 10 (2024): 1192–94. http://dx.doi.org/10.1016/j.jacbts.2024.07.011.

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3

McEniery, C. M., and I. B. Wilkinson. "Large artery stiffness and inflammation." Journal of Human Hypertension 19, no. 7 (2005): 507–9. http://dx.doi.org/10.1038/sj.jhh.1001814.

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4

Blacher, J., Athanase Protogerou, and M. Safar. "Large Artery Stiffness and Antihypertensive Agents." Current Pharmaceutical Design 11, no. 25 (2005): 3317–26. http://dx.doi.org/10.2174/138161205774424654.

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5

Chirinos, Julio A. "Echocardiographic Assessment of Large Artery Stiffness." Journal of the American Society of Echocardiography 29, no. 11 (2016): 1117–21. http://dx.doi.org/10.1016/j.echo.2016.09.004.

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6

Chirinos, Julio A. "Large Artery Stiffness and New-Onset Diabetes." Circulation Research 127, no. 12 (2020): 1499–501. http://dx.doi.org/10.1161/circresaha.120.318317.

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7

Kingwell, Bronwyn A., Tanya L. Medley, Tamara K. Waddell, Timothy J. Cole, Anthony M. Dart, and Garry L. Jennings. "Large Artery Stiffness: Structural And Genetic Aspects." Clinical and Experimental Pharmacology and Physiology 28, no. 12 (2001): 1040–43. http://dx.doi.org/10.1046/j.1440-1681.2001.03580.x.

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8

Butlin, Mark, and Ahmad Qasem. "Large Artery Stiffness Assessment Using SphygmoCor Technology." Pulse 4, no. 4 (2016): 180–92. http://dx.doi.org/10.1159/000452448.

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9

Tan, Isabella, Bart Spronck, Hosen Kiat, et al. "Heart Rate Dependency of Large Artery Stiffness." Hypertension 68, no. 1 (2016): 236–42. http://dx.doi.org/10.1161/hypertensionaha.116.07462.

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10

Chirinos, Julio A., Patrick Segers, Timothy Hughes, and Raymond Townsend. "Large-Artery Stiffness in Health and Disease." Journal of the American College of Cardiology 74, no. 9 (2019): 1237–63. http://dx.doi.org/10.1016/j.jacc.2019.07.012.

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11

Wagenseil, Jessica E., and Robert P. Mecham. "Elastin in Large Artery Stiffness and Hypertension." Journal of Cardiovascular Translational Research 5, no. 3 (2012): 264–73. http://dx.doi.org/10.1007/s12265-012-9349-8.

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12

Wakeham, Denis J., Gary L. Pierce, and Kevin S. Heffernan. "Effect of Acute Resistance Exercise and Resistance Exercise Training on Central Pulsatile Hemodynamics and Large Artery Stiffness: Part II." Pulse 13, no. 1 (2025): 45–61. https://doi.org/10.1159/000543314.

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Background: In part one of this two-part series, we performed a detailed analysis of the hemodynamic signature produced during resistance exercise (RE) and discussed the subacute effects on short-term modulation of large artery stiffness and central pulsatile hemodynamics. In this second part of our two-part series, we consider the subacute recovery window as the driver of resistance exercise training (RET) adaptations. We then discuss the results of RET interventions and corroborate these findings against the information gleaned from cross-sectional studies in habitually strength-trained athl

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13

Alivon, Maureen, Julie Giroux, Marie Briet, François Goldwasser, Stéphane Laurent, and Pierre Boutouyrie. "Large artery stiffness and hypertension after antiangiogenic drugs." Journal of Hypertension 33, no. 6 (2015): 1310–17. http://dx.doi.org/10.1097/hjh.0000000000000550.

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14

MORCET, J. "Influence of heart rate on large artery stiffness." American Journal of Hypertension 12, no. 4 (1999): 174. http://dx.doi.org/10.1016/s0895-7061(99)80629-3.

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15

van den Meiracker, Anton H., and Francesco US Mattace-Raso. "Large artery stiffness and microalbuminuria: a causal relationship?" Journal of Hypertension 27, no. 7 (2009): 1355–57. http://dx.doi.org/10.1097/hjh.0b013e32832d2149.

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16

Alivon, M., K. T. Ong, H. Khettab, et al. "6.2 LARGE ARTERY STIFFNESS ASSESSMENT WITH ARTERIOGRAPH DEVICE." Artery Research 4, no. 4 (2010): 149. http://dx.doi.org/10.1016/j.artres.2010.10.179.

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17

Stróżecki, Paweł, Zbigniew Serafin, Andrzej Adamowicz, Mariusz Flisiński, Zbigniew Włodarczyk, and Jacek Manitius. "Coronary artery calcification and large artery stiffness in renal transplant recipients." Advances in Medical Sciences 60, no. 2 (2015): 240–45. http://dx.doi.org/10.1016/j.advms.2015.04.002.

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18

Nardone, Massimo, John S. Floras, and Philip J. Millar. "Sympathetic neural modulation of arterial stiffness in humans." American Journal of Physiology-Heart and Circulatory Physiology 319, no. 6 (2020): H1338—H1346. http://dx.doi.org/10.1152/ajpheart.00734.2020.

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Elevated large-artery stiffness is recognized as an independent predictor of cardiovascular and all-cause mortality. The mechanisms responsible for such stiffening are incompletely understood. Several recent cross-sectional and acute experimental studies have examined whether sympathetic outflow, quantified by microneurographic measures of muscle sympathetic nerve activity (MSNA), can modulate large-artery stiffness in humans. A major methodological challenge of this research has been the capacity to evaluate the independent neural contribution without influencing the dynamic blood pressure de

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19

Chan, William, and Anthony M. Dart. "Vascular stiffness and aging in HIV." Sexual Health 8, no. 4 (2011): 474. http://dx.doi.org/10.1071/sh10160.

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Large artery stiffening is a biological index of vascular aging. Vascular aging and atherosclerosis are two closely linked processes that develop in parallel and in synergy, sharing common aetiological determinants. Vascular stiffening increases left ventricular work and can lead to diminished coronary perfusion, and may therefore contribute to the development of cardiovascular disease. There is emerging evidence that large artery stiffness and vascular aging are accelerated in HIV infection because of the high prevalence of cardiovascular risk factors among HIV-infected patients. Moreover, th

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20

Korhonen, Päivi, Kari Syvänen, and Pertti Aarnio. "Surrogates of Large Artery versus Small Artery Stiffness and Ankle-Brachial Index." International Journal of Angiology 20, no. 03 (2011): 167–72. http://dx.doi.org/10.1055/s-0031-1284200.

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21

Kingwell, Bronwyn A., Tamara K. Waddell, Tanya L. Medley, James D. Cameron, and Anthony M. Dart. "Large artery stiffness predicts ischemic threshold in patients with coronary artery disease." Journal of the American College of Cardiology 40, no. 4 (2002): 773–79. http://dx.doi.org/10.1016/s0735-1097(02)02009-0.

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22

Ahimastos, Anna A., Melissa Formosa, Anthony M. Dart, and Bronwyn A. Kingwell. "Gender Differences in Large Artery Stiffness Pre- and Post Puberty." Journal of Clinical Endocrinology & Metabolism 88, no. 11 (2003): 5375–80. http://dx.doi.org/10.1210/jc.2003-030722.

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Abstract Age-related large artery stiffening is more pronounced in women compared with men and is an important cause of isolated systolic hypertension. This study aimed to investigate whether such gender differences are inherent or the result of sex steroid influences. Healthy children prepuberty [26 female (10.3 ± 0.1 yr), 32 male (10.3 ± 0.1 yr), mean age ± sd] and post puberty [30 female (15.9 ± 0.2 yr), 22 male (15.9 ± 0.4 yr)] were studied. Large artery stiffness was assessed globally via systemic arterial compliance and regionally via pulse wave velocity. Prepubertal males and females di

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23

Premužić, Vedran, Ana Jelaković, Lea Katalinić, et al. "Large artery stiffness and sexual dysfunction in hemodialysis patients." Cardiologia Croatica 12, no. 3 (2017): 74. http://dx.doi.org/10.15836/ccar2017.74.

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24

Kingwell, Bronwyn, A. M. Dart, J. D. Cameron, et al. "CHOLESTEROL AND LARGE ARTERY STIFFNESS IN A HYPERTENSIVE POPULATION." Journal of Hypertension 22, Suppl. 1 (2004): S168. http://dx.doi.org/10.1097/00004872-200402001-00715.

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25

Kotsis, Vasilios, and Stella Stabouli. "Arterial Stiffness, Vascular Aging, and Intracranial Large Artery Disease." American Journal of Hypertension 24, no. 3 (2011): 252. http://dx.doi.org/10.1038/ajh.2010.251.

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26

Wilkinson, Ian B., Stanley S. Franklin, and John R. Cockcroft. "Nitric Oxide and the Regulation of Large Artery Stiffness." Hypertension 44, no. 2 (2004): 112–16. http://dx.doi.org/10.1161/01.hyp.0000138068.03893.40.

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27

Vehkavaara, Satu, Jukka Westerbacka, Tiina Hakala-Ala-Pietilä, Antti Virkamäki, Outi Hovatta, and Hannele Yki-Järvinen. "Effect of Estrogen Replacement Therapy on Insulin Sensitivity of Glucose Metabolism and Preresistance and Resistance Vessel Function in Healthy Postmenopausal Women1." Journal of Clinical Endocrinology & Metabolism 85, no. 12 (2000): 4663–70. http://dx.doi.org/10.1210/jcem.85.12.7034.

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In the present study, we hypothesized that estradiol, via its ability to vasodilate in an endothelium-dependent manner, might enhance vascular effects of insulin. Basal and insulin-stimulated peripheral blood flow and resistance, arterial stiffness, and glucose metabolism were determined in 27 healthy postmenopausal women before and after 12 weeks of treatment with either transdermal or oral estradiol or corresponding placebo preparations. Whole body insulin sensitivity was determined using the euglycemic insulin clamp technique (rate of continuous insulin infusion 1 mU/kg·min), forearm blood

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28

Bank, Alan J. "Physiologic Aspects of Drug Therapy and Large Artery Elastic Properties." Vascular Medicine 2, no. 1 (1997): 44–50. http://dx.doi.org/10.1177/1358863x9700200107.

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Vasoactive drugs alter smooth muscle tone not only in arterial resistance vessels, but also in large conduit arteries. The resultant changes in smooth muscle tone alter both conduit vessel size and stiffness and hence influence pulsatile components of left ventricular afterload. The effects of smooth muscle relaxation and contraction on arterial elastic properties are complex and have not been fully characterized. Several recent studies have utilized a new intravascular ultrasound technique to study the effects of changes in smooth muscle tone on brachial artery elastic mechanics in normal hum

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29

Rey-García, Jimena, and Raymond R. Townsend. "Large Artery Stiffness: A Companion to the 2015 AHA Science Statement on Arterial Stiffness." Pulse 9, no. 1-2 (2021): 1–10. http://dx.doi.org/10.1159/000518613.

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Large artery stiffness (LAS) has proven to be an independent risk factor for cardiovascular disease and mortality. Nevertheless, the position of current hypertension guidelines regarding the usefulness of assessing LAS differs across different continents. In general, European Guidelines recognize pulse wave velocity (PWV) as a marker of target organ damage but do not recommend its systematic use in general population. Asian guidelines consider PWV as a recommended test at diagnosis of hypertension, in contrast to North American guidelines that do not state any position about its usefulness. Ho

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30

Wakeham, Denis J., Gary L. Pierce, and Kevin S. Heffernan. "Effect of Acute Resistance Exercise and Resistance Exercise Training on Central Pulsatile Hemodynamics and Large Artery Stiffness: Part I." Pulse 13, no. 1 (2025): 31–44. https://doi.org/10.1159/000543313.

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Background: Engaging in habitual resistance exercise training (RET; also known as strength training) causes systemic health effects beyond those caused by aerobic/endurance exercise training alone. Despite the resoundingly favorable effect of habitual RET on measures of cardiovascular disease risk, controversy still exists regarding the vascular health effects of this exercise modality largely because some studies find increases in large artery stiffness and central pulsatile hemodynamics with RET. In this two-part series, we examine the effect of acute resistance exercise (RE) and RET on larg

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31

Gupta, Shresth, Anurag Singh, and Abhishek Sharma. "Dynamic Large Artery Stiffness Index for Cuffless Blood Pressure Estimation." IEEE Sensors Letters 6, no. 3 (2022): 1–4. http://dx.doi.org/10.1109/lsens.2022.3157060.

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32

Iannarelli, Nathaniel J., Kylie S. Dempster, Aindriu R. R. Maguire, et al. "Serum MMP‐3 and its Association with Large Artery Stiffness." FASEB Journal 34, S1 (2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.01878.

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33

Wohlfahrt, Peter, Alena Krajcoviechova, Marie Jozifova, et al. "Large artery stiffness and carotid flow pulsatility in stroke survivors." Journal of Hypertension 32, no. 5 (2014): 1097–103. http://dx.doi.org/10.1097/hjh.0000000000000137.

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34

Blacher, Jacques, and Michel E. Safar. "Large-artery stiffness, hypertension and cardiovascular risk in older patients." Nature Clinical Practice Cardiovascular Medicine 2, no. 9 (2005): 450–55. http://dx.doi.org/10.1038/ncpcardio0307.

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35

Palombo, C., C. Morizzo, F. Vittone, et al. "Visceral Adiposity and Large Artery Stiffness in Healthy Obese Subjects." High Blood Pressure & Cardiovascular Prevention 12, no. 3 (2005): 176. http://dx.doi.org/10.2165/00151642-200512030-00109.

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36

Kingwell, Bronwyn A. "Large Artery Stiffness: Implications For Exercise Capacity And Cardiovascular Risk." Clinical and Experimental Pharmacology and Physiology 29, no. 3 (2002): 214–17. http://dx.doi.org/10.1046/j.1440-1681.2002.03622.x.

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37

Strauss, Michél, Wayne Smith, Wen Wei, Alexei Y. Bagrov, Olga V. Fedorova, and Aletta E. Schutte. "Large artery stiffness is associated with marinobufagenin in young adults." Journal of Hypertension 36, no. 12 (2018): 2333–39. http://dx.doi.org/10.1097/hjh.0000000000001866.

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38

Aoun, S., J. Blacher, ME Safar, and JJ Mourad. "Diabetes mellitus and renal failure: effects on large artery stiffness." Journal of Human Hypertension 15, no. 10 (2001): 693–700. http://dx.doi.org/10.1038/sj.jhh.1001253.

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39

Hickler, R. B. "Aortic and large artery stiffness: Current methodology and clinical correlations." Clinical Cardiology 13, no. 5 (1990): 317–22. http://dx.doi.org/10.1002/clc.4960130504.

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40

van den Bogaard, B., C. Spaan, K. Lieve, G. A. van Montfrans, and B. J. H. van den Born. "P8.08HEMODYNAMICS AND LARGE ARTERY STIFFNESS IN YOUNG PREHYPERTENSIVE MEDICAL STUDENTS." Artery Research 3, no. 4 (2009): 188. http://dx.doi.org/10.1016/j.artres.2009.10.114.

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41

MILLASSEAU, S. C., R. P. KELLY, J. M. RITTER, and P. J. CHOWIENCZYK. "Determination of age-related increases in large artery stiffness by digital pulse contour analysis." Clinical Science 103, no. 4 (2002): 371–77. http://dx.doi.org/10.1042/cs1030371.

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The stiffness of the aorta can be determined by measuring carotid–femoral pulse wave velocity (PWVcf). PWV may also influence the contour of the peripheral pulse, suggesting that contour analysis might be used to assess large artery stiffness. An index of large artery stiffness (SIDVP) derived from the digital volume pulse (DVP) measured by transmission of IR light (photoplethysmography) was examined. SIDVP was obtained from subject height and from the time delay between direct and reflected waves in the DVP. The timing of these components of the DVP is determined by PWV in the aorta and large

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42

Schillaci, Giuseppe, and Giacomo Pucci. "Is ambulatory arterial stiffness index a marker of large-artery stiffness? Evidence from intervention studies." Hypertension Research 38, no. 12 (2015): 799–801. http://dx.doi.org/10.1038/hr.2015.101.

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43

Halabi, Carmen M., Thomas J. Broekelmann, Russell H. Knutsen, Li Ye, Robert P. Mecham, and Beth A. Kozel. "Chronic antihypertensive treatment improves pulse pressure but not large artery mechanics in a mouse model of congenital vascular stiffness." American Journal of Physiology-Heart and Circulatory Physiology 309, no. 5 (2015): H1008—H1016. http://dx.doi.org/10.1152/ajpheart.00288.2015.

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Increased arterial stiffness is a common characteristic of humans with Williams-Beuren syndrome and mouse models of elastin insufficiency. Arterial stiffness is associated with multiple negative cardiovascular outcomes, including myocardial infarction, stroke, and sudden death. Therefore, identifying therapeutic interventions that improve arterial stiffness in response to changes in elastin levels is of vital importance. The goal of this study was to determine the effect of chronic pharmacologic therapy with different classes of antihypertensive medications on arterial stiffness in elastin ins

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44

Briet, Marie. "Mineralocorticoid Receptor, the Main Player in Aldosterone-Induced Large Artery Stiffness." Hypertension 63, no. 3 (2014): 442–43. http://dx.doi.org/10.1161/hypertensionaha.113.02581.

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45

Saito, M., H. Okayama, K. Nishimura, et al. "Possible link between large artery stiffness and coronary flow velocity reserve." Heart 94, no. 6 (2008): e20-e20. http://dx.doi.org/10.1136/hrt.2007.126128.

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46

Chirinos, Julio A., Mayank Sardana, Amer Ahmed Syed, et al. "Aldosterone, inactive matrix gla-protein, and large artery stiffness in hypertension." Journal of the American Society of Hypertension 12, no. 9 (2018): 681–89. http://dx.doi.org/10.1016/j.jash.2018.06.018.

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47

Seals, Douglas R., Christopher A. DeSouza, Anthony J. Donato, and Hirofumi Tanaka. "Habitual exercise and arterial aging." Journal of Applied Physiology 105, no. 4 (2008): 1323–32. http://dx.doi.org/10.1152/japplphysiol.90553.2008.

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Aging affects the function and structure of arteries and increases the risk of cardiovascular diseases (CVD). In healthy sedentary adults, aging is associated with increased stiffness (reduced compliance) of large elastic arteries; impaired vascular endothelial function, including reductions in endothelium-dependent dilation (EDD), release of tissue-type plasminogen activator (fibrinolytic capacity) and endothelial progenitor cell number and function; increased intima-media wall thickness (IMT); and peripheral vasoconstriction (decreased basal leg blood flow). Habitual physical activity/increa

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48

Yu, Shikai, and Carmel M. McEniery. "Central Versus Peripheral Artery Stiffening and Cardiovascular Risk." Arteriosclerosis, Thrombosis, and Vascular Biology 40, no. 5 (2020): 1028–33. http://dx.doi.org/10.1161/atvbaha.120.313128.

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The large elastic arteries fulfill an important role in buffering the cyclical changes in blood pressure, which result from intermittent ventricular ejection. With aging and accrual of cardiovascular risk factors, the elastic arteries stiffen, and this process holds a number of deleterious consequences for the cardiovascular system and major organs. Indeed, arterial stiffness is now recognized as an important, independent determinant of cardiovascular disease risk. Additional, important information concerning the mechanisms underlying arterial stiffening has come from longitudinal studies of a

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49

Obeid, Hasan, Catherine Fortier, Charles-Antoine Garneau, et al. "Radial-digital pulse wave velocity: a noninvasive method for assessing stiffness of small conduit arteries." American Journal of Physiology-Heart and Circulatory Physiology 320, no. 4 (2021): H1361—H1369. http://dx.doi.org/10.1152/ajpheart.00551.2020.

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Aortic stiffness, a cardiovascular risk factor and a marker of arterial aging, is assessed by pulse wave velocity (PWV) over this arterial segment. The interaction between the stiffness of various arterial segments is important in understanding the behavior of pressure and flow waves along the arterial tree. However, PWV assessment has been limited to large elastic vessels (aorta) or medium-sized arteries (i.e., brachial artery). In this paper, we provide a novel and noninvasive method of assessing the regional stiffness of small conduit arteries using the same piezoelectric sensors used for d

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50

Ferreira, Isabel, Marieke B. Snijder, Jos W. R. Twisk, et al. "Central Fat Mass Versus Peripheral Fat and Lean Mass: Opposite (Adverse Versus Favorable) Associations with Arterial Stiffness? The Amsterdam Growth and Health Longitudinal Study." Journal of Clinical Endocrinology & Metabolism 89, no. 6 (2004): 2632–39. http://dx.doi.org/10.1210/jc.2003-031619.

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Abstract Central and peripheral fatness seem to confer opposite (i.e. adverse vs. protective) effects on cardiovascular risk, but how this occurs is not clear. In addition, the role of peripheral lean mass needs to be elucidated. We therefore investigated, in 336 (175 women) 36-yr-old and apparently healthy adults, the relationship between trunk fat, peripheral fat, and peripheral lean mass on the one hand, and estimates of stiffness of three large arteries on the other. Body composition was assessed by dual-energy x-ray absorptiometry. Arterial properties were assessed by ultrasound imaging.

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