Relevant bibliographies by topics / Large signal response

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Large signal response'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Large signal response"

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Ludge, Kathy, Roland Aust, Gerrit Fiol, et al. "Large-Signal Response of Semiconductor Quantum-Dot Lasers." IEEE Journal of Quantum Electronics 46, no. 12 (2010): 1755–62. http://dx.doi.org/10.1109/jqe.2010.2066959.

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Pennington, P. N., and R. F. Ormondroyd. "Large-signal modulation response of monolithic active integrated-optic waveguides." IEE Proceedings J Optoelectronics 137, no. 1 (1990): 11. http://dx.doi.org/10.1049/ip-j.1990.0004.

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Torres Pereira, J. M. "Large-signal modulation response of 1.3 ?m InGaAsP MQW lasers." Microwave and Optical Technology Letters 30, no. 6 (2001): 375–78. http://dx.doi.org/10.1002/mop.1319.

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Senseman, David M. "Correspondence between visually evoked voltage-sensitive dye signals and synaptic activity recorded in cortical pyramidal cells with intracellular microelectrodes." Visual Neuroscience 13, no. 5 (1996): 963–77. http://dx.doi.org/10.1017/s0952523800009196.

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AbstractFast, multiple-site optical recording of voltage-sensitive dye (VSD) signals and intracellular microelectrode recordings were combined to characterize visually evoked neuronal responses in the visual cortex of the pond turtle, Pseudemys scripta. By using an in vitro, eye-brain preparation stained with the merocyanine oxazolone voltage-sensitive dye, NK-2495 or a close analog, NK-2761, large VSD signals relatively free of vibrational noise could be recorded in single trials following a stroboscopic light flash to the contralateral eye. VSD signals recorded from the same cortical locatio
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Wang, Lin Ze, Wen Li Zhao, and Bei Bei Xia. "Comparative Research on Stochastic Resonance of Piecewise-Linear Model and Bi-Stable Model." Applied Mechanics and Materials 44-47 (December 2010): 2701–6. http://dx.doi.org/10.4028/www.scientific.net/amm.44-47.2701.

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A new piecewise-linear stochastic resonance model was proposed in this paper. Using numerical simulation, the model was compared with nonlinear one-dimensional continuous bi-stable system on response to period signals under both noisy and non-noisy circumstances. Comparing with contrasting model, there is no output response saturation phenomenon, and the output will increase greatly with the increasing of input signal. To input signal with noise, there is larger applicability to noise intense, especially to weak signal with large additive noise, still there is stochastic resonance. It is super
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Wang, Xiao, Xiao-Hong Zhu, Yi Zhang, and Wei Chen. "Large Enhancement of Perfusion Contribution on fMRI Signal." Journal of Cerebral Blood Flow & Metabolism 32, no. 5 (2012): 907–18. http://dx.doi.org/10.1038/jcbfm.2012.26.

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The perfusion contribution to the total functional magnetic resonance imaging (fMRI) signal was investigated using a rat model with mild hypercapnia at 9.4 T, and human subjects with visual stimulation at 4 T. It was found that the total fMRI signal change could be approximated as a linear superposition of ‘true’ blood oxygenation level-dependent (BOLD; T2/T2*) effect and the blood flow-related ( T1) effect. The latter effect was significantly enhanced by using short repetition time and large radiofrequency pulse flip angle and became comparable to the ‘true’ BOLD signal in response to a mild
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Sherlock, Nevin P., and Richard J. Meyer. "Large signal response and harmonic distortion in piezoelectrics for SONAR transducers." Journal of Electroceramics 28, no. 2-3 (2012): 202–7. http://dx.doi.org/10.1007/s10832-012-9708-5.

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Yu, Wen Wen, Hao Tian, Hai Qi Zheng, and Dong Gen Chen. "Tower Modal Parameters Identification Based on Polymax Method." Applied Mechanics and Materials 229-231 (November 2012): 1823–26. http://dx.doi.org/10.4028/www.scientific.net/amm.229-231.1823.

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Based on the background of a high tower structure under environment random excitation, large-scale complex system parameter identification based on Polymax method is presented in this paper. Firstly,the system of testing environment excitation response signal for large tower is designed.Secondly,the obtained signal is analysed and intercepted,then the ideal signals are selectted from each experiment. Lastly, the intercepted signal is identified for some parameters based on polymax method.The obtained result shows that the former is effective.
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Ouslimani, A., G. Vernet, P. Crozat, and R. Adde. "Large-signal model of picosecond FETs and measurement of the step response." IEEE Transactions on Microwave Theory and Techniques 37, no. 9 (1989): 1460–65. http://dx.doi.org/10.1109/22.32231.

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Gutin, Alexey, Trond Ytterdal, Valentin Kachorovskii, Andrey Muraviev, and Michael Shur. "THz SPICE for Modeling Detectors and Nonquadratic Response at Large Input Signal." IEEE Sensors Journal 13, no. 1 (2013): 55–62. http://dx.doi.org/10.1109/jsen.2012.2224105.

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Dissertations / Theses on the topic "Large signal response"

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Clerjaud, Lilian. "Méthode d’hétérodynage pour la caractérisation de propriétés thermophysiques par thermographie infrarouge dans une large gamme spatiale et temporelle." Thesis, Bordeaux 1, 2010. http://www.theses.fr/2010BOR14040/document.

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De nos jours, l’apport de la miniaturisation a permis d’innombrables progrès scientifiques et techniques : de la microélectronique à la microfluidique et dernièrement les nanotechnologies. Autant de domaines où les enjeux économiques de suivi de qualité ou d’optimisation de production peuvent nécessiter une étape de caractérisation des propriétés intrinsèques des constituants. Parmi ces propriétés, les données thermophysiques permettent notamment de définir la capacité à stocker ou diffuser la chaleur (conductivité, effusivité ou conductivité thermique par exemple). Une manière d’estimer ces p
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Chadha, Ankit. "Tapped-Inductor Buck DC-DC Converter." Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1578488939749599.

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Cardoso, Adilson Silva. "Design and characterization of BiCMOS mixed-signal circuits and devices for extreme environment applications." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53099.

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State-of-the-art SiGe BiCMOS technologies leverage the maturity of deep-submicron silicon CMOS processing with bandgap-engineered SiGe HBTs in a single platform that is suitable for a wide variety of high performance and highly-integrated applications (e.g., system-on-chip (SOC), system-in-package (SiP)). Due to their bandgap-engineered base, SiGe HBTs are also naturally suited for cryogenic electronics and have the potential to replace the costly de facto technologies of choice (e.g., Gallium-Arsenide (GaAs) and Indium-Phosphide (InP)) in many cryogenic applications such as radio astronomy. T
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Wibbeler, Jürgen. "Frequenzselektive Vibrationssensoren mit spannungsgesteuerter Resonanzabstimmung in Oberflächenmikromechanik." Doctoral thesis, Universitätsbibliothek Chemnitz, 2003. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200301366.

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Basic resonator structures for frequency-selective capacitive vibration sensors which exploit their mechanical resonance peak for spectral selectivity are developed and analyzed. As an important capability, the stuctures offer voltage-controlled frequency tuning realized by electrostatic principles. Direct electrostatic tuning based on displacement-dependent electrostatic forces as well as tuning by stress-stiffening based on constant electrostatic forces are discussed. The sensor structures are designed for fabrication using common silicon surface microtechnologies. Experimental tests of both
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Abdelaziz, Sherif Lotfy Abdel Motaleb. "Study and Evaluation of Traffic Responsive Control on a Large Arterial Network." Thesis, Virginia Tech, 2008. http://hdl.handle.net/10919/34298.

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Traffic responsive mode of operation with its two mechanisms, threshold-based and pattern matching, is considered one of the effective and efficient signal control modes. This operation mode is underutilized due to its cumbersome configuration procedure. The research presented in this thesis aims to give some guidelines regarding traffic responsive and issues that might improve the system performance. Four different issues related to traffic responsive are considered: The first issue is the generation of different traffic scenarios that drive the design of the system. This point is not limite
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Wibbeler, Jürgen. "Frequenzselektive Vibrationssensoren mit spannungsgesteuerter Resonanzabstimmung in Oberflächenmikromechanik." Doctoral thesis, 2002. https://monarch.qucosa.de/id/qucosa%3A18071.

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Basic resonator structures for frequency-selective capacitive vibration sensors which exploit their mechanical resonance peak for spectral selectivity are developed and analyzed. As an important capability, the stuctures offer voltage-controlled frequency tuning realized by electrostatic principles. Direct electrostatic tuning based on displacement-dependent electrostatic forces as well as tuning by stress-stiffening based on constant electrostatic forces are discussed. The sensor structures are designed for fabrication using common silicon surface microtechnologies. Experimental tests of bot
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Books on the topic "Large signal response"

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Wigmans, Richard. Calibrating a Calorimeter System. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198786351.003.0006.

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One of the most important aspects of operating a calorimeter is the calibration, i.e. determining the relationship between the deposited energy and the resulting signal. Segmenting the calorimeter into two or more longitudinal segments creates extremely complicated problems in this context. This is because the sampling fraction and the calorimeter response tend to change as the shower develops, in an energy dependent way. In this chapter, a large variety of methods that have been proposed and/or tried to deal with these problems are described. Almost all these methods have undesirable side eff
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Frost, William, and Jian-young Wu. Voltage-Sensitive Dye Imaging. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199939800.003.0008.

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Voltage sensitive dye imaging (VSD) can be used to record neural activity in hundreds of locations in preparations ranging from mammalian cortex to invertebrate ganglia. Because fast VSDs respond to membrane potential changes with microsecond temporal resolution, these are better suited than calcium indicators for recording rapid neural signals. Here we describe methods for using a 464- element photodiode array and fast VSDs to record signals ranging from large scale network activity in brain slices and in vivo mammalian preparations, to action potentials in over 100 individual neurons in inve
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Beninger, Richard J. Neuroanatomy and dopamine systems. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198824091.003.0011.

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Neuroanatomy and dopamine systems explains how sensory signals ascend the central nervous system via a series of nuclei; axons detecting specific elements converge onto higher-order neurons that respond to particular stimulus features. Assemblies of feature-detection cells in the cerebral cortex detect complex stimuli such as faces. These cell assemblies project to motor nuclei of the dorsal and ventral striatum where they terminate on dendritic spines of efferent medium spiny neurons. Dopaminergic projections from ventral mesencephalic nuclei terminate on the same spines. Individual corticost
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Lopes da Silva, Fernando H., and Eric Halgren. Neurocognitive Processes. Edited by Donald L. Schomer and Fernando H. Lopes da Silva. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228484.003.0048.

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Transmembrane neuronal currents that embody cognition in the cortex produce magnetoencephalographic and electroencephalographic signals. Frequency-domain analysis reveals standard rhythms with consistent topography, frequency, and cognitive correlates. Time-domain analysis reveals average event-related potentials and field (ERP/ERF) components with consistent topography, latency, and cognitive correlates. Standard rhythms and ERP/ERF components underlie perceiving stimuli; evaluating whether stimuli match predictions, and taking appropriate action when they do not; encoding stimuli to permit s
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Seth, Anil K. Consciousness. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0037.

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Consciousness is perhaps the most familiar aspect of our existence, yet we still do not know its biological basis. This chapter outlines a biomimetic approach to consciousness science, identifying three principles linking properties of conscious experience to potential biological mechanisms. First, conscious experiences generate large quantities of information in virtue of being simultaneously integrated and differentiated. Second, the brain continuously generates predictions about the world and self, which account for the specific content of conscious scenes. Third, the conscious self depends
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Troisi, Alfonso. Deception. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199393404.003.0006.

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For a long time, biological studies of communication have been based on the postulate that communication has evolved to ensure the transmission of veridical information between conspecifics. Ethological studies of a variety of animal species have demonstrated that transmission of false information is a relevant component of intraspecific signals and that the adaptive benefit of deceiving others was a driving force in the evolution of communication. In primate species, evolving a larger neocortex was a viable evolutionary strategy to respond to environmental challenges that demand enhanced capa
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Holmes, Jonathan, and Philipp Hoelzmann. The Late Pleistocene-Holocene African Humid Period as Evident in Lakes. Oxford University Press, 2017. http://dx.doi.org/10.1093/acrefore/9780190228620.013.531.

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From the end of the last glacial stage until the mid-Holocene, large areas of arid and semi-arid North Africa were much wetter than present, during the interval that is known as the African Humid Period (AHP). During this time, large areas were characterized by a marked increase in precipitation, an expansion of lakes, river systems, and wetlands, and the spread of grassland, shrub land, and woodland vegetation into areas that are currently much drier. Simulations with climate models indicate that the AHP was the result of orbitally forced increase in northern hemisphere summer insolation, whi
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Spevetz, Antoinette, and Joseph E. Parrillo. Diagnosis and management of shock in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0150.

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Sepsis is triggered by an infection and treatment of sepsis requires timely identification of the patient, and rapid treatment with antibiotics, source control, and fluids. In the absence of a true biomarker for sepsis, the clinician needs to recognize which patients are at risk, as well as the common signs and symptoms of infection. The site of infection, the patient’s phenotype, and the location of the patient will help drive decisions about initial antibiotic therapy. Patients with sepsis should be treated to ensure adequate cardiac output and organ perfusion, which usually requires infusio
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Sepúlveda, Jovanny, ed. Investigación en pedagogía y educación: Reflexiones, retos y proposiciones. CUA - Medellin, 2020. http://dx.doi.org/10.52441/edu202005.

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Escribir este preliminar, es para quien lo hace una especie de defensa, y como bien plantea su definición, el prólogo a veces es ajeno a la esencia del texto mismo, puede ser un valor añadido. En este caso, más que el valor complemento, lo que pretendo dejar es la clave para entrar en la esencia del trabajo que usted tiene en sus manos. Y lo hago de esta manera porque no hay duda que en un mundo como el presente se hace necesario crecer como humanos, social y comunitariamente tenemos mucho por hacer, pero especialmente en el campo de la pedagogía, y en la educación, seguimos teniendo mucho por
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Alexander, D. J., N. Phin, and M. Zuckerman. Influenza. Edited by I. H. Brown. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0037.

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Influenza is a highly infectious, acute illness which has affected humans and animals since ancient times. Influenza viruses form the Orthomyxoviridae family and are grouped into types A, B, and C on the basis of the antigenic nature of the internal nucleocapsid or the matrix protein. Infl uenza A viruses infect a large variety of animal species, including humans, pigs, horses, sea mammals, and birds, occasionally producing devastating pandemics in humans, such as in 1918 when it has been estimated that between 50–100 million deaths occurred worldwide.There are two important viral surface glyc
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Book chapters on the topic "Large signal response"

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Kosina, H., M. Nedjalkov, and S. Selberherr. "Monte Carlo Analysis of the Small-Signal Response of Charge Carriers." In Large-Scale Scientific Computing. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/3-540-45346-6_17.

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Burt, J. A., K. Yang, J. J. Caldwell, R. N. Halthore, and J. E. Allen. "Methane Vibrational Rates from Deconvoluting a Large Data Set with Varying Pressure, Buffer Gases, Temperature, Signal-to-Noise Ratio, and Instrumental Response." In Photoacoustic and Photothermal Phenomena III. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-540-47269-8_70.

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Eremin, Sergey. "Immunochemical methods for detection of organophosphorus compounds." In ORGANOPHOSPHORUS NEUROTOXINS. Publishing Center RIOR, 2020. http://dx.doi.org/10.29039/33_219-230.

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Organophosphorus compounds (OP) are found in environmental objects and food products. Due to their high toxicity and inhibition of cholinesterase activity, it is necessary to control residual amounts of OP. The most common methods for determining OP are gas and liquid chromatography with various detection methods. However, chromatographic analysis is lengthy, requires complex sample preparation and expensive equipment, which limits its use for screening a large number of samples and continuous monitoring of the content of OP. To detect the OP, it is necessary to use High Throughput Screening methods, using simple, fast and inexpensive analysis methods. Currently, immunochemical methods are increasingly used to determine OP. These methods are based on the recognition of the analyte (antigen) by specific receptors (antibodies) with the formation of the antigen-antibody complex and the measurement of the analytical signal generated by the immunochemical test system in response to complex formation, which leads to high sensitivity and specificity of the analysis.
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M., Suchetha, and Jagannath M. "Biosignal Denoising Techniques." In Handbook of Research on Information Security in Biomedical Signal Processing. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-5152-2.ch002.

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The main aim of ECG signal enhancement is to separate the required signal components from the unwanted artifacts. Adaptive filter-based ECG enhancement helps in detecting time varying potentials and also helps to track the dynamic variations of the signals. LMS-based adaptive recurrent filter is used to obtain the impulse response of normal QRS complexes. It is also used for arrhythmia detection in ambulatory ECG recordings. Adaptive filters self-modify its frequency response to change the behavior in time. This property of adaptive filter allows it to adapt its response to change in the input signal characteristics. A major problem in adaptive filtering is the computational complexity of adaptive algorithm when the unknown system has a long impulse response and therefore requires a large number of taps. The wavelet transform is a time-scale representation method with a basis function called mother wavelet. In wavelet transform, the input signal is subsequently decomposed into subbands. Wavelet transform thresholding in the subband gives better performance of denoising.
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Zhang, Chuang, Longlong He, Suzhen Liu, and Qingxin Yang. "Simulation and Experimental Study of Closed Crack Detection by Ultrasonic Nonlinearity Under Electromagnetic Loading." In Studies in Applied Electromagnetics and Mechanics. IOS Press, 2020. http://dx.doi.org/10.3233/saem200017.

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The reliability of micro-damage detection of metal materials plays a crucial role in the safe and reliable operation of large equipment. In recent years, nonlinear ultrasonic nondestructive testing technology has achieved good development in closed cracks detection, but the problem of nonlinear ultrasonic detection of closed cracks is weak response signal and vulnerable to external interference. This paper realizes the modulation of the ultrasonic wave by electromagnetic loading at the closed cracks, which can effectively enrich the frequency components of nonlinear ultrasonic and magnify the amplitude. This lays a foundation for further research on nonlinear ultrasonic detection of closed cracks under electromagnetic loading.
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Afifi, Walaa Abd el aal, Hesham Ahmed Hefny, Nagy Ramadan Darwish, and Imane Fahmy. "Relative Position Estimation in Vehicle Ad-Hoc Network." In IoT and Cloud Computing Advancements in Vehicular Ad-Hoc Networks. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-2570-8.ch003.

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Position is a vital element for ITS applications. Its accuracy helps to deliver services quickly to drivers to increase their satisfaction. GPS is a well-known position system but it suffers from multipath effect and non-line of sight in tunnel environments. Relative Position or sometimes called cooperative localization is an alternative position estimation. It utilizes different forms of v2x communication to exchange position, distance, direction, and velocity parameters. It will benefit in collecting a large amount of data to increase the accuracy of position estimation. However, the dependency of radio range communication methods has drawbacks such as poor-received signal, multipath, lose packets, delay, and overhead communication that will have inverse impact on position accuracy. In addition, safety applications require fewer seconds to make quick response. This chapter provides the latest related papers, the state art of radio range, the well-known localization algorithms, and current challenges and future direction.
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Kumar, Prabhat, and Amritesh Kumar. "Analysis and Design of a Parallel Switched-Inductor DC-DC Converter." In Computational Methodologies for Electrical and Electronics Engineers. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-3327-7.ch008.

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This chapter proposes a switched inductor configuration-based non-isolated DC-DC converter with high voltage gain. The proposed converter has two output capacitors instead of a single output capacitor for voltage boosting capabilities. Enhancement of the output voltage with the addition of more number of switched inductor cells is also possible in this configuration. The most advantageous factor of this proposed converter is the use of low-voltage semiconductor devices as they don't require large heat sinks. The converter operation in the steady state is fully analyzed. In addition to that, for the purpose of stability analysis, the small signal model for the proposed converter has also been developed. The frequency response using the small-scale transfer function of the converter has also been done by employing MATLAB. A suitable controller with suitable parameters has also been designed to improve the overall stability of the DC-DC converter in consideration. The results obtained after simulation verifies the feasibility of the converter.
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Hanahan, Donald J. "Phospholipid(s) Associations in Cellular Structures." In A Guide to Phospholipid Chemistry. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780195079814.003.0005.

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In the preceding chapter, the intent was to provide the reader with a broad perspective on the chemical characteristics of cellular phospholipids. At the same time, emphasis was placed on the potential usefulness of this information in dissecting the importance of phospholipids in cellular events, such as signal transduction. There is no doubt that the large number of observations reported on the close relationship of phospholipids to the transduction process has stimulated a widespread (and gratifying) interest in these compounds. Certainly it is very clear now that stimulus-induced activation of cells leads to the turnover of specific membrane phospholipids. The following diagram reemphasizes several, but not all, possible reaction pathways that can be invoked during an agonist (stimulus)–induced activation of a cell and gives the possible sequelae: In each of the above reactions, the substrates phosphatidylcholine and phosphatidylinositol bisphosphate normally are considered biologically inactive in membranes. Then, subsequent to activation of cellular phospholipases by a stimulus, biologically active products are formed from these compounds. Thus, inositol bisphosphate triggers the release of calcium ions from intracellular stores, diacylglycerol is implicated in the translocation and activation of protein kinase C, arachidonic acid can be converted to biologically active prostaglandins, and phosphatidic acid can be an agonist in its own right. The major point to be stressed here is that phospholipid turnover is intimately associated with the signal transduction pathway in cells. Hence an understanding of the chemistry of these phospholipids is of major relevance to delineating the complicated process of signal transduction. While investigation of the behavior of phospholipids in this pathway in platelets has been a consuming interest of this author, the main thrust in this book will be simply to acquaint the reader with the chemistry of phospholipids of major importance in signal transduction and also to discuss other phospholipids found in mammalian membranes. Inasmuch as most investigations on stimulus response in cells utilize quite small numbers of cells—for example, a typical experiment on human platelets might use 1 x 109 cells, which would yield ∼50 μg of total lipid—this poses a challenge to an investigator to be able to isolate and identify these lipids.
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Funder, John W. "Hormones and receptors: fundamental considerations." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.1022.

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The original endocrine physiologists viewed hormones as responses to homoeostatic challenge, any signal a call to arms; the word is thus derived from the classical Greek ωρμαειν‎—‘to arouse’. In the twenty-first century a hormone is a molecule—small or large, protein or lipid—secreted in a regulated fashion from one organ and acting on another. The definition is firmly based on the anatomy of the seventeenth century, the histology of the nineteenth, and the physiology of the twentieth. It has been shaped by convention and clinical specialization: gut hormones are the marches between endocrinology and gastroenterology, and the adrenal medulla the territory of the cardiovascular physician. It has been refined by concepts of paracrine—where the secretion of one cell type in a tissue acts on another cell type in the same tissue—and autocrine, where a particular cell type both secretes and responds to a particular signal. Inherent in the concepts of paracrine and autocrine are that the signal is not secreted into blood or lymph, to be distributed more or less throughout the body, but is made locally to act locally. A very good example of a signalling system with both paracrine and autocrine activities is the neuronal synapse. Inherent in the concept of the signal is that of a receptor: a signal without a receptor is the sound of one hand clapping. Inherent in the concept of a receptor are two functions: that of being able to discriminate between different signals, and to propagate the signal by activating cell membrane or intracellular signal transduction pathways. Discrimination by a receptor between different circulating potential signals is, in the first instance, a function of the likelihood of a particular signal being able to interact with the receptor, for a period of time sufficient to alter the confirmation of the receptor and thus to trigger propagation. This interaction is commonly referred to as binding, and thus the circulating hormone as a ligand (that which is bound). If the structures of ligand and receptors are such that the initial interaction is followed by formation of strong intermolecular bonds between the two, lessening the possibility of dissociation and the receptor returning to an unliganded state, the receptor is said to have high affinity for the ligand (and vice versa). If the binding is followed by propagation of the ‘appropriate’ signal the ligand is classified as an agonist, or active hormone; if a molecule occupies the binding site on the receptor but does not so alter its structure as to propagate a signal, it is classified as a hormone antagonist (and often, by extension, a receptor antagonist). In the past couple of decades, the concepts of ‘agonist’ and ‘antagonist’ have needed to be refined, as noted subsequently in this chapter.
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Benarroch, Eduardo E. "Intracellular Signaling." In Neuroscience for Clinicians, edited by Eduardo E. Benarroch. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190948894.003.0003.

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Interactions between cells in the nervous system are bidirectional and involve a large number of chemical signals. These interactions occur via receptors located at presynaptic terminals, postsynaptic processes, or at a distance. Activation of membrane receptors by neurotransmitters, growth factors, cytokines, or other extracellular signals triggers downstream intracellular signaling pathways that affect a wide range of cellular functions. The final common mechanism is regulation of the state of phosphorylation of multiple crucial proteins in membranes, cytosol, cytoskeleton, and nucleus. The coupling between extracellular signals and these intracellular responses depends on transduction pathways that include G proteins that function as molecular switches; second messenger molecules such as cyclic nucleotides and phosphatidylinositol metabolites; intracellular calcium transients; and activation of protein kinases and phosphatases. Alterations of these fundamental cellular mechanisms provide the bases for a large number of disorders of the nervous system as well as potential therapeutic targets.
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Conference papers on the topic "Large signal response"

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Qingshui Li, X. Wang, and I. Batarseh. "Large signal compensation network design for VRM transient response improvement." In 31st Annual Conference of IEEE Industrial Electronics Society, 2005. IECON 2005. IEEE, 2005. http://dx.doi.org/10.1109/iecon.2005.1569065.

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Hickman, Austin, Reet Chaudhuri, Neil Moser, et al. "Large Signal Response of AlN/GaN/AlN HEMTs at 30 GHz." In 2021 Device Research Conference (DRC). IEEE, 2021. http://dx.doi.org/10.1109/drc52342.2021.9467196.

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Ouslimani, A., G. Vem, and R. Adde. "Step Response and very Large-Signal Modeling of FETS at Picosecond Scales." In 19th European Microwave Conference, 1989. IEEE, 1989. http://dx.doi.org/10.1109/euma.1989.333993.

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Hyuk-Kee Sung, E. K. Lau, M. C. Wu, D. Tishinin, Liou KY, and W. T. Tsang. "Large-signal analog modulation response of monolithic optical injection-locked DFB lasers." In 2005 Conference on Lasers and Electro-Optics (CLEO). IEEE, 2005. http://dx.doi.org/10.1109/cleo.2005.202012.

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Kaatuzian, Hassan, and Hamid Pahlevaninezhad. "Transient response analysis of semiconductor lasers at high frequency large signal pulse modulation." In Southeastcon 2008. IEEE, 2008. http://dx.doi.org/10.1109/secon.2008.4494332.

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Barmuta, Pawe, Gustavo Avolio, Francesco Ferranti, Arkadiusz Lewandowski, and Dominique Schreurs. "Large-signal modeling of on-wafer microwave transistors based on response surface methodology." In 2015 IEEE MTT-S International Microwave Symposium (IMS2015). IEEE, 2015. http://dx.doi.org/10.1109/mwsym.2015.7167029.

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Mohammadi, Mehdi, and Martin Ordonez. "Fast transient response of series resonant converter using an average large signal model." In 2015 IEEE Energy Conversion Congress and Exposition. IEEE, 2015. http://dx.doi.org/10.1109/ecce.2015.7309687.

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Watanabe, Kazufumi, Koji Kotani, Akinobu Teramoto, Shigetoshi Sugawa, and Tadahiro Ohmi. "A Large-Signal MOSFET Model Based on Transient Carrier Response for RF Circuits." In 2004 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 2004. http://dx.doi.org/10.7567/ssdm.2004.a-10-2.

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Rolain, Yves, Wendy Van Moer, Rik Pintelon, and Johan Schoukens. "Measuring the Response of a Voltage Controlled Oscillator using the Large-Signal Network Analyser." In 2007 IEEE Instrumentation & Measurement Technology Conference IMTC 2007. IEEE, 2007. http://dx.doi.org/10.1109/imtc.2007.379388.

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Deng, H., D. L. Huffaker, J. Shin, and D. G. Deppe. "Dependence of Large Signal Response on the Transverse Mode Structure in Vertical-Cavity Lasers." In Ultrafast Electronics and Optoelectronics. OSA, 1995. http://dx.doi.org/10.1364/ueo.1995.utue13.

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Reports on the topic "Large signal response"

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Vera, Cesar Allan, Ma Lourdes Brusola-Vera, Maria Rosario Felizco, and Janice Ian Manlutac. Local Humanitarian Leadership: The View from Local Actors. Oxfam, 2021. http://dx.doi.org/10.21201/2021.7574.

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The global call for localization and locally led emergency response acknowledges the reality that the humanitarian system is currently organized around international actors. More than the limited access to direct funding, the core issue is the power imbalance between local and international actors. In the Philippines, national and local networks of humanitarian, faith-based, developmental organizations and private sector foundations have been conducting and leading small- and large-scale disaster responses for decades. However, the discourse and struggle for localization have grown in recent y
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Kuznetsov, Victor, Vladislav Litvinenko, Egor Bykov, and Vadim Lukin. A program for determining the area of the object entering the IR sensor grid, as well as determining the dynamic characteristics. Science and Innovation Center Publishing House, 2021. http://dx.doi.org/10.12731/bykov.0415.15042021.

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Currently, to evaluate the dynamic characteristics of objects, quite a large number of devices are used in the form of chronographs, which consist of various optical, thermal and laser sensors. Among the problems of these devices, the following can be distinguished: the lack of recording of the received data; the inaccessibility of taking into account the trajectory of the object flying in the sensor area, as well as taking into consideration the trajectory of the object during the approach to the device frame. The signal received from the infrared sensors is recorded in a separate document in
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Vargas-Herrera, Hernando, Juan Jose Ospina-Tejeiro, Carlos Alfonso Huertas-Campos, et al. Monetary Policy Report - April de 2021. Banco de la República de Colombia, 2021. http://dx.doi.org/10.32468/inf-pol-mont-eng.tr2-2021.

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1.1 Macroeconomic summary Economic recovery has consistently outperformed the technical staff’s expectations following a steep decline in activity in the second quarter of 2020. At the same time, total and core inflation rates have fallen and remain at low levels, suggesting that a significant element of the reactivation of Colombia’s economy has been related to recovery in potential GDP. This would support the technical staff’s diagnosis of weak aggregate demand and ample excess capacity. The most recently available data on 2020 growth suggests a contraction in economic activity of 6.8%, lowe
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