Relevant bibliographies by topics / Lasentec FBRM

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  1. Journal articles
  2. Dissertations / Theses
  3. Conference papers

Academic literature on the topic 'Lasentec FBRM'

Author: Grafiati
Published: 4 June 2021
Last updated: 12 February 2022

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Journal articles on the topic "Lasentec FBRM"

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Worlitschek, Jörg, and Marco Mazzotti. "Choice of the Focal Point Position Using Lasentec FBRM." Particle & Particle Systems Characterization 20, no. 1 (February 2003): 12–17. http://dx.doi.org/10.1002/ppsc.200390000.

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Adlington, Neil K., Simon N. Black, and David L. Adshead. "How To Use the Lasentec FBRM Probe on Manufacturing Scale." Organic Process Research & Development 17, no. 3 (February 21, 2013): 557–67. http://dx.doi.org/10.1021/op300326b.

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Sathe, Dhananjay, Kamlesh Sawant, Harish Mondkar, Tushar Naik, and Manoj Deshpande. "Monitoring Temperature Effect on the Polymorphic Transformation of Acitretin Using FBRM−Lasentec." Organic Process Research & Development 14, no. 6 (November 19, 2010): 1373–78. http://dx.doi.org/10.1021/op100177s.

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Barrett, P., and B. Glennon. "Characterizing the Metastable Zone Width and Solubility Curve Using Lasentec FBRM and PVM." Chemical Engineering Research and Design 80, no. 7 (October 2002): 799–805. http://dx.doi.org/10.1205/026387602320776876.

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Mitchell, Niall A., Patrick J. Frawley, and Clifford T. Ó’Ciardhá. "Nucleation kinetics of paracetamol–ethanol solutions from induction time experiments using Lasentec FBRM®." Journal of Crystal Growth 321, no. 1 (April 2011): 91–99. http://dx.doi.org/10.1016/j.jcrysgro.2011.02.027.

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Schirg, P., and P. Wissler. "Verfolgung und Optimierung der Kühlungskristallisation von Vitamin C mit einer Lasentec FBRM In-line-Partikelmesssonde." Chemie Ingenieur Technik 72, no. 9 (September 2000): 941. http://dx.doi.org/10.1002/1522-2640(200009)72:9<941::aid-cite9410>3.0.co;2-x.

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Schirg, Peter, and Patrick Wissler. "Verfolgung und Optimierung der Kühlungskristallisation von Vitamin C mit einer Lasentec FBRM In-line-Partikelmesssonde." Chemie Ingenieur Technik 73, no. 4 (April 2001): 377–81. http://dx.doi.org/10.1002/1522-2640(200104)73:4<377::aid-cite377>3.0.co;2-w.

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Zidan, Ahmed S., Ziyaur Rahman, and Mansoor A. Khan. "Online Monitoring of PLGA Microparticles Formation Using Lasentec Focused Beam Reflectance (FBRM) and Particle Video Microscope (PVM)." AAPS Journal 12, no. 3 (March 30, 2010): 254–62. http://dx.doi.org/10.1208/s12248-010-9184-2.

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Choi, Y. C., and E. Morgenroth. "Monitoring biofilm detachment under dynamic changes in shear stress using laser-based particle size analysis and mass fractionation." Water Science and Technology 47, no. 5 (March 1, 2003): 69–76. http://dx.doi.org/10.2166/wst.2003.0284.

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Biofilm detachment under a dynamic change in shear stress was monitored using Focused Beam Reflectance Measurements (FBRM, LASENTEC®) and mass fractionation. An annular reactor was used to grow biofilm with glucose as substrate. Changing the rotational speed on the inner cylinder of the annular reactor from 150 RPM to 420 RPM induced a step increase in shear stress. It was observed that the rate of detachment increased rapidly after increasing shear stress and then returned to the previous level. Erosion was the dominant process of detachment under steady state operation, whereas sloughing was dominant following the sudden increase in shear stress. After reaching steady state detachment under high shear conditions, the rotational speed was decreased for a 12-hour period. During this brief period of lower shear, the biofilm adjusted to this new condition. When the shear stress was increased again, another sharp increase in effluent solids concentration was observed. A decrease in density indicates that the biofilm became more vulnerable to shear stress after being subjected to this short period of low shear.
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Kougoulos, E., A. G. Jones, and M. W. Wood-Kaczmar. "Modelling particle disruption of an organic fine chemical compound using Lasentec focussed beam reflectance monitoring (FBRM) in agitated suspensions." Powder Technology 155, no. 2 (July 2005): 153–58. http://dx.doi.org/10.1016/j.powtec.2005.05.033.

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Dissertations / Theses on the topic "Lasentec FBRM"

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Novák, David. "Studium polymorfie a optimalizace krystalizace farmaceuticky aktivních látek." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2008. http://www.nusl.cz/ntk/nusl-216442.

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Active pharmaceutical ingredients (APIs) are frequently delivered to the patient in the solid-state as part of an approved dosage form (tablets, capsules, etc.). Understanding and controlling the solid-state chemistry of APIs is therefore an important aspect of the drug development process. APIs can exist in a variety of distinct solid forms, including polymorphs, solvates, hydrates, co-crystals and amorphous solids. Each form displays unique physicochemical properties that can profoundly influence the bioavailability, manufacturability, stability and other performance characteristics of the drug. Most APIs are purified and isolated by crystallisation from an appropriate solvent during the final step in synthetic process. The main objective of a crystallisation process is to produce crystals with desired properties such as particle size distribution (PSD), shape and purity. All pharmaceutical dosage forms must be produced in uniform units, and good content of uniformity is only possible when the size of the active component is carefully controlled. For on-line control of crystallisations of Quetiapine Fumarate to achieve desired PSD and no changed physicochemical purity was used the Lasentec Focus Beam Reflectance Measurement (FBRM) system.
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Mendez, del Rio Jose R. "Solubility and phase transitions in batch and laminar-flow tubular crystallizers." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/4876.

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The research addressed in this thesis focuses on monitoring and characterization of pharmaceutical compounds by laser backscattering. In particular, this study covers two topics: (1) the determination of naproxen sodium solubility in water, and its phase transition; and (2) comparisons of batch and laminar flow tubular crystallizers for the production of paracetamol (acetaminophen) and D-mannitol. Using a Lasentec™ Focused Beam Reflectance Measurement (FBRM) device, the solubility of naproxen sodium in aqueous solutions was determined over a temperature range from 15.2 to 39.7 ℃ With the determination of the solubilities of two pseudopolymorphs, anhydrous and dihydrated naproxen sodium, the phase transition point between these two forms of the pharmaceutical compound was determined to occur at 30.3 ℃ Enthalpy of solution and metastable zone widths were also determined for the experimental conditions. Crystallizations of paracetamol and D-mannitol were performed in a batch crystallizer and in a laminar flow tubular crystallizer (LFTC) system. In the latter system, supersaturation was generated rapidly in the solution being transported through a temperature-controlled tube and recovered in a batch vessel where product crystals were grown to equilibration. Because of the rapid rate at which supersaturation was generated in the LFTC, the resulting crystals were of smaller mean size than those obtained from batch crystallizations. The total time required for crystallization was significantly less with the LFTC than with the batch unit. Additionally, the rapid cooling in the LFTC led to the formation of two different polymorphs of paracetamol, Forms I and II.
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Conference papers on the topic "Lasentec FBRM"

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Daymo, Eric A., Tom D. Hylton, and Thomas H. May. "Acceptance testing of the Lasentec focused beam reflectance measurement (FBRM) monitor for slurry transfer applications at Hanford and Oak Ridge." In Photonics East (ISAM, VVDC, IEMB), edited by David E. Robertson. SPIE, 1999. http://dx.doi.org/10.1117/12.339060.

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