Log in

Relevant bibliographies by topics / Laser-assisted microdissection / Journal articles

To see the other types of publications on this topic, follow the link: Laser-assisted microdissection.

Journal articles on the topic 'Laser-assisted microdissection'

Author: Grafiati

Published: 7 July 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Laser-assisted microdissection.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Chimge, Nyam-Osor, Frank Ruddle, and Dashzeveg Bayarsaihan. "Laser-assisted microdissection (LAM) in developmental biology." Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 308B, no. 2 (2007): 113–18. http://dx.doi.org/10.1002/jez.b.21133.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Sirivatanauksorn, Yongyut, Rosybel Drury, Tatjana Crnogorac-Jur?evi?, Vorapan Sirivatanauksorn, and Nicholas R. Lemoine. "Laser-assisted microdissection: applications in molecular pathology." Journal of Pathology 189, no. 2 (1999): 150–54. http://dx.doi.org/10.1002/(sici)1096-9896(199910)189:2<150::aid-path451>3.0.co;2-g.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Cör, Andrej, N. Vogt, and B. Malfoy. "Microdissection Techniques for Cancer Analysis." Folia Biologica 48, no. 1 (2002): 3–8. https://doi.org/10.14712/fb2002048010003.

Full text

Abstract:

One difficulty in studying molecular changes of tumours has been the inability to isolate DNA and RNA from a homogeneous cell population. The combination of several new technologies should help overcome these hurdles. Microdissection is a technique for rapid and easy procurement of a pure cellular subpopulation away from its complex tissue milieu. Laser-assisted microdissection has recently been identified as a quick, simple and effective method by which microdissection of complex tissue specimens can be routinely performed for molecular analysis. With the advent of laser microdissection, cDNA

APA, Harvard, Vancouver, ISO, and other styles

4

Day, Robert C., Ueli Grossniklaus, and Richard C. Macknight. "Be more specific! Laser-assisted microdissection of plant cells." Trends in Plant Science 10, no. 8 (2005): 397–406. http://dx.doi.org/10.1016/j.tplants.2005.06.006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Blakey, Gregory L., and Zoltan G. Laszik. "Laser-assisted microdissection of the kidney: Fundamentals and applications." Histochemical Journal 35, no. 6 (2004): 581–87. http://dx.doi.org/10.1007/s10735-004-2195-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Pinzani, P., C. Orlando, and M. Pazzagli. "Laser-assisted microdissection for real-time PCR sample preparation." Molecular Aspects of Medicine 27, no. 2-3 (2006): 140–59. http://dx.doi.org/10.1016/j.mam.2005.12.006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Small, HJ, J. Sturve, JP Bignell, et al. "Laser-assisted microdissection: a new tool for aquatic molecular parasitology." Diseases of Aquatic Organisms 82 (November 20, 2008): 151–56. http://dx.doi.org/10.3354/dao01983.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Fink, Ludger, Stephanie Kohlhoff, Maria Magdalena Stein, et al. "cDNA Array Hybridization after Laser-Assisted Microdissection from Nonneoplastic Tissue." American Journal of Pathology 160, no. 1 (2002): 81–90. http://dx.doi.org/10.1016/s0002-9440(10)64352-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Prasad, Rachana, and Ajay Mallick. "Comparison of Microdissection Microlaryngeal Surgery with Carbon Dioxide Laser in Management of Benign and Premalignant Lesions of Larynx." Bengal Journal of Otolaryngology and Head Neck Surgery 26, no. 3 (2018): 190–96. http://dx.doi.org/10.47210/bjohns.2018.v26i3.208.

Full text

Abstract:

Introduction Dysphonia is caused by voice misuse and various environmental factors. It is manifested as varied pathological lesions of the vocal cords. Surgical excision of these lesions is mainly by conventional cold steel or laser assisted microsurgical techniques. Both modalities have seen extensive advancements and refinement in technologies in the recent past. In this study we have compared the microdissection microlaryngeal treatment and microspot superpulsed beam carbon dioxide (CO2) laser assisted surgical techniques for the management of benign and precancerous lesions of the vo

APA, Harvard, Vancouver, ISO, and other styles

10

Montag Ph.D., Markus, Katrin van der Ven M.D., Guy Delacrétaz Ph.D., Klaus Rink Ph.D., and Hans van der Ven M.D. "Laser-Assisted Microdissection of the Zona Pellucida Facilitates Polar Body Biopsy." Fertility and Sterility 69, no. 3 (1998): 539–42. http://dx.doi.org/10.1016/s0015-0282(97)00538-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Kuhn, Donald E., Sashwati Roy, Jared Radtke, Sudip Gupta, and Chandan K. Sen. "Laser microdissection and pressure-catapulting technique to study gene expression in the reoxygenated myocardium." American Journal of Physiology-Heart and Circulatory Physiology 290, no. 6 (2006): H2625—H2632. http://dx.doi.org/10.1152/ajpheart.01346.2005.

Full text

Abstract:

For focal events such as myocardial infarction, it is important to dissect infarction-induced biological responses as a function of space with respect to the infarct core. Laser microdissection pressure catapulting (LMPC) represents a recent variant of laser capture microdissection that enables robot-assisted rapid capture of catapulted tissue without direct user contact. This work represents the maiden effort to apply laser capture microdissection to study spatially resolved biological responses in myocardial infarction. Infarcted areas of the surviving ischemic-reperfused murine heart were i

APA, Harvard, Vancouver, ISO, and other styles

12

Mitchell, Natalie M., Surendra Dasari, Thomas E. Grys, and Douglas F. Lake. "Laser Capture Microdissection-Assisted Protein Biomarker Discovery from Coccidioides-Infected Lung Tissue." Journal of Fungi 6, no. 4 (2020): 365. http://dx.doi.org/10.3390/jof6040365.

Full text

Abstract:

Laser capture microdissection (LCM) coupled to label-free quantitative mass spectrometry is a viable strategy to identify biomarkers from infected tissues. In this study, LCM was employed to take a “snapshot” of proteins produced in vivo during Coccidiodies spp. infection in human lungs. Proteomic analysis of LCM lung sections revealed hundreds of hosts and Coccidioidal proteins. Twenty-seven highly abundant Coccidioides spp. proteins were identified which do not share significant sequence orthology with human proteins. Three of the 27 Coccidioidal proteins are also potential Coccidoides-speci

APA, Harvard, Vancouver, ISO, and other styles

13

Yao, Virginia J., Michael G. Ozawa, Martin Trepel, Wadih Arap, Donald M. McDonald, and Renata Pasqualini. "Targeting Pancreatic Islets with Phage Display Assisted by Laser Pressure Catapult Microdissection." American Journal of Pathology 166, no. 2 (2005): 625–36. http://dx.doi.org/10.1016/s0002-9440(10)62283-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Eberle, Franziska C., Jeffrey C. Hanson, J. Keith Killian, et al. "Immunoguided Laser Assisted Microdissection Techniques for DNA Methylation Analysis of Archival Tissue Specimens." Journal of Molecular Diagnostics 12, no. 4 (2010): 394–401. http://dx.doi.org/10.2353/jmoldx.2010.090200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

von der Hardt, Katharina, Michael Andreas Kandler, Ludger Fink, et al. "Laser-assisted microdissection and real-time PCR detect anti-inflammatory effect of perfluorocarbon." American Journal of Physiology-Lung Cellular and Molecular Physiology 285, no. 1 (2003): L55—L62. http://dx.doi.org/10.1152/ajplung.00198.2002.

Full text

Abstract:

The aim of this study was to identify cell types involved in the anti-inflammatory effect of ventilation with perfluorocarbon in vivo. Fifteen anesthetized, surfactant-depleted piglets received either aerosolized perfluorocarbon (Aerosol-PFC), partial liquid ventilation (rLV) at functional residual capacity (FRC) volume (FRC-PLV), or intermittent mandatory ventilation (control). After laser-assisted microdissection of different lung cell types, mRNA expression of IL-8 and ICAM-1 was determined using TaqMan real-time PCR normalized to hypoxanthine phosphoribosyltransferase (HPRT). IL-8 mRNA exp

APA, Harvard, Vancouver, ISO, and other styles

16

Gjerdrum, Lise Mette, Ilze Lielpetere, Lars Melholt Rasmussen, Knud Bendix, and Stephen Hamilton-Dutoit. "Laser-Assisted Microdissection of Membrane-Mounted Paraffin Sections for Polymerase Chain Reaction Analysis." Journal of Molecular Diagnostics 3, no. 3 (2001): 105–10. http://dx.doi.org/10.1016/s1525-1578(10)60659-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Kenngott, R., A. AL-Banaw, M. Vermehren, J. Wendl, and F. Sinowatz. "Application of Laser-Assisted Microdissection for Gene Expression Analysis of Mammalian Germ Cells." Anatomia, Histologia, Embryologia 39, no. 3 (2010): 219–26. http://dx.doi.org/10.1111/j.1439-0264.2010.00997.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Kwapiszewska, Grazyna, Jai Prakash Muyal, Björn Lengemann, et al. "Characterization of platelet-specific mRNA by real-time PCR after laser-assisted microdissection." Thrombosis and Haemostasis 90, no. 10 (2003): 749–56. http://dx.doi.org/10.1160/th03-02-0095.

Full text

Abstract:

SummaryCirculating anucleate platelets contain minute amounts of residual megakaryocytic-derived mRNA. To study cell type-specific gene expression in platelets, an accurate and sensitive method to detect and quantify platelet mRNA that excludes contamination with leukocyte RNA is mandatory. Applying laser-assisted microdissection and manipulation (LMM) we could isolate platelets from hemalaun-stained cytospins under permanent visual control and after laser-photolysis of nucleated blood cells. For mRNA quantification, the platelet-specific mRNAs were subsequently measured by real time RT-PCR. H

APA, Harvard, Vancouver, ISO, and other styles

19

Philipson, Thomas, Marissa Howard, Kevin Johnson, et al. "Abstract 3768: Optimization of digital pathology through laser capture microdissection with a 405 nm laser." Cancer Research 84, no. 6_Supplement (2024): 3768. http://dx.doi.org/10.1158/1538-7445.am2024-3768.

Full text

Abstract:

Abstract Tumor cellular heterogeneity is a complex problem in cancer molecular diagnostics and personalized therapy. The tumor is a product of the different types and interactions of host and immune cells. Investigators have created a variety of methods to procure separate subpopulations of the tumor microenvironment for individual analysis. One of the most successful methods of this is laser capture microdissection (LCM). This method captures specific subpopulations of cells under direct microscopic visualization. This LCM technology has successfully been used for over 20 years, revealing a v

APA, Harvard, Vancouver, ISO, and other styles

20

Huang, Haibo, Yifan Pan, Yan Pang, et al. "Piezoelectric Ultrasonic Biological Microdissection Device Based on a Novel Flexure Mechanism for Suppressing Vibration." Micromachines 12, no. 2 (2021): 196. http://dx.doi.org/10.3390/mi12020196.

Full text

Abstract:

Biological microdissection has a wide range of applications in the field of molecular pathology. The current laser-assisted dissection technology is expensive. As an economical microdissection method, piezoelectric ultrasonic microdissection has broad application prospects. However, the performance of the current piezoelectric ultrasonic microdissection technology is unsatisfactory. This paper aims to solve the problems of the low dissecting precision and excessive wear of the dissecting needle caused by the harmful lateral vibration of the present piezoelectric ultrasonic microdissection devi

APA, Harvard, Vancouver, ISO, and other styles

21

Klink, Vincent P., Giselle Thibaudeau, and Ronald Altig. "A Novel Sample Preparation Method That Enables Nucleic Acid Analysis from Ultrathin Sections." Microscopy and Microanalysis 19, no. 3 (2013): 635–41. http://dx.doi.org/10.1017/s1431927613000044.

Full text

Abstract:

AbstractThe ability to isolate and perform nucleic acid analyses of individual cells is critical to studying the development of various cell types and structures. We present a novel biological sample preparation method developed for laser capture microdissection-assisted nucleic acid analysis of ultrathin cell/tissue sections. We used cells of the mitotic bed of the tadpole teeth of Lithobates sphenocephalus (Southern Leopard Frog). Cells from the mitotic beds at the base of the developing teeth series were isolated and embedded in the methacrylate resin, Technovit® 9100®. Intact cells of the

APA, Harvard, Vancouver, ISO, and other styles

22

Hernández, Hernán Guillermo, Adrián Gabriel Sandoval-Hernández, Pablo Garrido-Gil, et al. "Alzheimer's disease DNA methylome of pyramidal layers in frontal cortex: laser-assisted microdissection study." Epigenomics 10, no. 11 (2018): 1365–82. http://dx.doi.org/10.2217/epi-2017-0160.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

POST, RORY J., ANDREAS KRUGER, and STELLA B. SOMIARI. "Laser-assisted microdissection of polytene chromosomes from Diptera for the development of molecular markers." Molecular Ecology Notes 6, no. 3 (2006): 634–37. http://dx.doi.org/10.1111/j.1471-8286.2006.01369.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

POST, R. J., J. L. CRAINEY, A. BIVAND, and A. RENZ. "Laser-assisted microdissection for the study of the ecology of parasites in their hosts." Molecular Ecology Resources 9, no. 2 (2009): 480–86. http://dx.doi.org/10.1111/j.1755-0998.2008.02437.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Brauns, Tilmann C., and Manfred Goos. "Micromanipulation of single cells from tissue imprints is an alternative to laser-assisted microdissection." Journal of Cutaneous Pathology 32, no. 7 (2005): 461–66. http://dx.doi.org/10.1111/j.0303-6987.2005.00269.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Giuffrè, Giuseppe, Annegret Müller, Thomas Brodegger, et al. "Microsatellite Analysis of Hereditary Nonpolyposis Colorectal Cancer-Associated Colorectal Adenomas by Laser-Assisted Microdissection." Journal of Molecular Diagnostics 7, no. 2 (2005): 160–70. http://dx.doi.org/10.1016/s1525-1578(10)60542-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Saal, Isabelle, Anne Gustin, Katia Rombaut, et al. "Laser-assisted microdissection applied to frozen surgical pathologic specimens - methodological aspects on RT-PCR." Journal of Experimental Therapeutics and Oncology 3, no. 6 (2003): 325–35. http://dx.doi.org/10.1111/j.1533-869x.2003.01106.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Alevizos, Ilias, Mamatha Mahadevappa, Xue Zhang, et al. "Oral cancer in vivo gene expression profiling assisted by laser capture microdissection and microarray analysis." Oncogene 20, no. 43 (2001): 6196–204. http://dx.doi.org/10.1038/sj.onc.1204685.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Burnet, Philip W. J., Sharon L. Eastwood, and Paul J. Harrison. "Laser-assisted microdissection: methods for the molecular analysis of psychiatric disorders at a cellular resolution." Biological Psychiatry 55, no. 2 (2004): 107–11. http://dx.doi.org/10.1016/s0006-3223(03)00642-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Nakanishi, Yoko, Gou Mizutani, Makoto Sano, Toshinori Oinuma, and Norimichi Nemoto. "Comparison of HER2 mRNA Amplification with Immunohistochemistry in Human Breast Cancer Using Laser Assisted Microdissection Technique." ACTA HISTOCHEMICA ET CYTOCHEMICA 37, no. 2 (2004): 73–79. http://dx.doi.org/10.1267/ahc.37.73.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Santi, Simonetta, and Wolfgang Schmidt. "Laser microdissection-assisted analysis of the functional fate of iron deficiency-induced root hairs in cucumber." Journal of Experimental Botany 59, no. 3 (2008): 697–704. http://dx.doi.org/10.1093/jxb/erm351.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Peiser, Christian, Marcello Trevisani, David A. Groneberg, et al. "Dopamine type 2 receptor expression and function in rodent sensory neurons projecting to the airways." American Journal of Physiology-Lung Cellular and Molecular Physiology 289, no. 1 (2005): L153—L158. http://dx.doi.org/10.1152/ajplung.00222.2004.

Full text

Abstract:

Agonists of the dopamine receptors have been demonstrated to have bronchodilatory properties in pathologically constricted airways. The mechanism by which these agonists induce bronchodilatation is thought to involve airway sensory nerves. In this study, the expression and function of dopamine D2 receptor were examined in sensory ganglia supplying the airways. Neuronal dopamine D2 receptor mRNA expression was demonstrated by single-cell RT-PCR following laser-assisted microdissection. The projection of the neurons to the airways was confirmed by retrograde neuronal labeling. In functional stud

APA, Harvard, Vancouver, ISO, and other styles

33

Iida, Yuko, Yasuhiro Gon, Yoko Nakanishi, et al. "Genomic analysis between idiopathic pulmonary fibrosis and associated lung cancer using laser‐assisted microdissection: A case report." Thoracic Cancer 12, no. 9 (2021): 1449–52. http://dx.doi.org/10.1111/1759-7714.13924.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Nagai-Okatani, Chiaki, Misugi Nagai, Takashi Sato, and Atsushi Kuno. "An Improved Method for Cell Type-Selective Glycomic Analysis of Tissue Sections Assisted by Fluorescence Laser Microdissection." International Journal of Molecular Sciences 20, no. 3 (2019): 700. http://dx.doi.org/10.3390/ijms20030700.

Full text

Abstract:

Lectin microarray (LMA) is a highly sensitive technology used to obtain the global glycomic profiles of endogenous glycoproteins in biological samples including formalin-fixed paraffin-embedded tissue sections. Here, we describe an effective method for cell type-selective glycomic profiling of tissue fragments collected by laser microdissection (LMD) under fluorescent histochemical visualization. We optimized each step of histochemical staining and confirmed the reliability and validity of glycomic profiling. Using the optimized procedure, glycomic profiles were obtained with 0.5 mm2 of staine

APA, Harvard, Vancouver, ISO, and other styles

35

Selmaj, Krzysztof, Zofia Pawłowska, Agata Walczak, Wiktor Koziołkiewicz, Cedric S. Raine, and Czesław S. Cierniewski. "Corpora amylacea from multiple sclerosis brain tissue consists of aggregated neuronal cells." Acta Biochimica Polonica 55, no. 1 (2008): 43–50. http://dx.doi.org/10.18388/abp.2008_3199.

Full text

Abstract:

In this report, we describe proteomic analysis of corpora amylacea collected by postmortem laser microdissection from multiple sclerosis (MS) brain lesions. Using low level protein loads (about 30 microg), a combination of two-dimensional electrophoresis with matrix-assisted laser desorption/ionization-time of flight mass spectrometry and database interrogations we identified 24 proteins of suspected neuronal origin. In addition to major cytoskeletal proteins like actin, tubulin, and vimentin, we identified a variety of proteins implicated specifically in cellular motility and plasticity (F-ac

APA, Harvard, Vancouver, ISO, and other styles

36

Kenngott, R., G. Palma, M. J. Wendl, M. Vermehren, and F. Sinowatz. "213 ANALYSIS OF STEROID HORMONE RECEPTOR GENE EXPRESSION IN THE BOVINE OVARY AFTER LASER-CAPTURE MICRODISSECTION." Reproduction, Fertility and Development 22, no. 1 (2010): 264. http://dx.doi.org/10.1071/rdv22n1ab213.

Full text

Abstract:

Developmental processes in complex organs like the ovary are difficult to study in terms of a biochemical and molecular biological analysis. Laser-assisted microdissection allows the efficient and precise capture of single cells or groups of cells of an organ within the context of time and space and permits their subsequent molecular characterization. Together with real-time PCR techniques, it is now feasible to study gene expression in defined cell populations of complex tissues, but it is essential to create standards optimized for fixation, preparation, and isolation of RNA, reverse transcr

APA, Harvard, Vancouver, ISO, and other styles

37

Schmid, Marc W., Anja Schmidt, Ulrich C. Klostermeier, Matthias Barann, Philip Rosenstiel, and Ueli Grossniklaus. "A Powerful Method for Transcriptional Profiling of Specific Cell Types in Eukaryotes: Laser-Assisted Microdissection and RNA Sequencing." PLoS ONE 7, no. 1 (2012): e29685. http://dx.doi.org/10.1371/journal.pone.0029685.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Kleeberger, Wolfram, Thomas Rothämel, Sabine Glöckner, Ulrich Lehmann, and Hans Kreipe. "Laser-Assisted Microdissection and Short Tandem Repeat PCR for the Investigation of Graft Chimerism after Solid Organ Transplantation." Pathobiology 68, no. 4-5 (2000): 196–201. http://dx.doi.org/10.1159/000055923.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

TIAN, XUE-FEI, XUE-GONG FAN, YAN ZHANG, YAN HUANG, HONG DAI, and RUO-SU YING. "Procuration and identification of bacteria in paraffin-embedded liver tissues of hepatocellular carcinoma by laser-assisted microdissection technique." APMIS 116, no. 1 (2008): 10–15. http://dx.doi.org/10.1111/j.1600-0463.2008.00739.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Tømmerås, Karin, Ingunn Bakke, Arne K. Sandvik, Erik Larsson, and Helge L. Waldum. "Rat parietal cells express CCK2 receptor mRNA: gene expression analysis of single cells isolated by laser-assisted microdissection." Biochemical and Biophysical Research Communications 297, no. 2 (2002): 335–40. http://dx.doi.org/10.1016/s0006-291x(02)02202-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Pinzani, P., C. Orlando, and M. Pazzagli. "Corrigendum to “Laser-assisted microdissection for real-time PCR sample preparation” [JMAM 27 (2–3) (2006) 140–159]." Molecular Aspects of Medicine 29, no. 3 (2008): 201. http://dx.doi.org/10.1016/j.mam.2006.11.001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Gautam, Vibhav, and Ananda K. Sarkar. "Laser Assisted Microdissection, an Efficient Technique to Understand Tissue Specific Gene Expression Patterns and Functional Genomics in Plants." Molecular Biotechnology 57, no. 4 (2014): 299–308. http://dx.doi.org/10.1007/s12033-014-9824-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Himmel, Lauren E., Troy A. Hackett, Jessica L. Moore, et al. "Beyond the H&E: Advanced Technologies for in situ Tissue Biomarker Imaging." ILAR Journal 59, no. 1 (2018): 51–65. http://dx.doi.org/10.1093/ilar/ily004.

Full text

Abstract:

AbstractFor decades, histopathology with routine hematoxylin and eosin staining has been and remains the gold standard for reaching a morphologic diagnosis in tissue samples from humans and veterinary species. However, within the past decade, there has been exponential growth in advanced techniques for in situ tissue biomarker imaging that bridge the divide between anatomic and molecular pathology. It is now possible to simultaneously observe localization and expression magnitude of multiple protein, nucleic acid, and molecular targets in tissue sections and apply machine learning to synthesiz

APA, Harvard, Vancouver, ISO, and other styles

44

Fede, Jacquelyn, Stephen Kogut, Anthony Heyward, et al. "21746 Antigen discovery in membranous glomerulopathy using laser capture microdissection and mass spectrometry." Journal of Clinical and Translational Science 5, s1 (2021): 1–2. http://dx.doi.org/10.1017/cts.2021.405.

Full text

Abstract:

ABSTRACT IMPACT: Identifying the causative antigen in membranous glomerulopathy cohorts enables the development of serum assays to detect and monitor disease progression without the need for invasive kidney biopsies. OBJECTIVES/GOALS: Primary membranous glomerulopathy is caused by the formation of autoantibody immune complexes which deposit in the glomerulus and obstruct kidney function. Causative antigens remain to be identified in roughly 20% of cases. Our goal is to identify the antigen in these cohorts, so that non-invasive assays can be developed for disease monitoring. METHODS/STUDY POPU

APA, Harvard, Vancouver, ISO, and other styles

45

Glöckner, Sabine, Ulrich Lehmann, Nadine Wilke, Wolfram Kleeberger, Florian Länger, and Hans Kreipe. "Detection of Gene Amplification in Intraductal and Infiltrating Breast Cancer by Laser-Assisted Microdissection and Quantitative Real-Time PCR." Pathobiology 68, no. 4-5 (2000): 173–79. http://dx.doi.org/10.1159/000055920.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Ruzicka, W. B., A. Zhubi, M. Veldic, D. R. Grayson, E. Costa, and A. Guidotti. "Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection." Molecular Psychiatry 12, no. 4 (2007): 385–97. http://dx.doi.org/10.1038/sj.mp.4001954.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

null, null. "P8-03: Exact quantification of gene amplification in archival tissue sections by laser-assisted microdissection and real-time PCR." Breast Cancer Research 2, Suppl 1 (2000): S41. http://dx.doi.org/10.1186/preaccept-158393212.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

O'Brien, Philippa M., David W. M. Millan, Jonathon A. Davis, and M. Saveria Campo. "In Situ Isolation of Immunoglobulin Sequences Expressed by Single Tumor-Infiltrating B Cells Using Laser-Assisted Microdissection." Molecular Biotechnology 29, no. 2 (2005): 101–10. http://dx.doi.org/10.1385/mb:29:2:101.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Aubele, Michaela, Horst Zitzelsberger, Ulrich Schenck, Axel Walch, Heinz H�fler, and Martin Werner. "Distinct cytogenetic alterations in squamous intraepithelial lesions of the cervix revealed by laser-assisted microdissection and comparative genomic hybridization." Cancer 84, no. 6 (1998): 375–79. http://dx.doi.org/10.1002/(sici)1097-0142(19981225)84:6<375::aid-cncr10>3.0.co;2-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Dou, Peng, Huan Yang, Miao Bao, et al. "Laser capture microdissection-assisted gas chromatography–triple-quadruple mass spectrometry for spatial metabolic profiling of esophageal squamous cell carcinoma." Journal of Pharmaceutical and Biomedical Analysis 265 (November 2025): 117036. https://doi.org/10.1016/j.jpba.2025.117036.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!