Academic literature on the topic 'Late-stage labeling'

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Journal articles on the topic "Late-stage labeling"

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Wang, Wei, Mélanie M. Lorion, Oscar Martinazzoli, and Lutz Ackermann. "BODIPY Peptide Labeling by Late‐Stage C(sp 3 )−H Activation." Angewandte Chemie 130, no. 33 (2018): 10714–18. http://dx.doi.org/10.1002/ange.201804654.

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Wang, Wei, Mélanie M. Lorion, Oscar Martinazzoli, and Lutz Ackermann. "BODIPY Peptide Labeling by Late‐Stage C(sp 3 )−H Activation." Angewandte Chemie International Edition 57, no. 33 (2018): 10554–58. http://dx.doi.org/10.1002/anie.201804654.

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Fulka, Helena, Milan Mrazek, Olga Tepla, and Josef Fulka. "DNA methylation pattern in human zygotes and developing embryos." Reproduction 128, no. 6 (2004): 703–8. http://dx.doi.org/10.1530/rep.1.00217.

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We report on observations of the global methylation/demethylation pattern of both pronuclei in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate that in about half of the zygotes examined the paternal chromatin was less methylated than the maternal chromatin. In the other half, both pronuclei exhibited the same intensity of labeling. The nuclei in developing embryos were intensively labeled for up to the four-cell stage; thereafter, a decline of labeling intensity was detected. Remethylation in some nuclei starts in late morulae. Surprisingly, and unlike th
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Del Vecchio, Antonio, Fabien Caillé, Arnaud Chevalier, et al. "Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2." Angewandte Chemie 130, no. 31 (2018): 9892–96. http://dx.doi.org/10.1002/ange.201804838.

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Del Vecchio, Antonio, Fabien Caillé, Arnaud Chevalier, et al. "Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2." Angewandte Chemie International Edition 57, no. 31 (2018): 9744–48. http://dx.doi.org/10.1002/anie.201804838.

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Reilly, Sean W., Frank Bennett, Patrick S. Fier, Sumei Ren, and Neil A. Strotman. "Late‐Stage 18 O Labeling of Primary Sulfonamides via a Degradation–Reconstruction Pathway." Chemistry – A European Journal 26, no. 19 (2020): 4251–55. http://dx.doi.org/10.1002/chem.202000484.

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Ricardo, Manuel G., Dayma Llanes, Ludger A. Wessjohann, and Daniel G. Rivera. "Introducing the Petasis Reaction for Late‐Stage Multicomponent Diversification, Labeling, and Stapling of Peptides." Angewandte Chemie International Edition 58, no. 9 (2019): 2700–2704. http://dx.doi.org/10.1002/anie.201812620.

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Ricardo, Manuel G., Dayma Llanes, Ludger A. Wessjohann, and Daniel G. Rivera. "Introducing the Petasis Reaction for Late‐Stage Multicomponent Diversification, Labeling, and Stapling of Peptides." Angewandte Chemie 131, no. 9 (2019): 2726–30. http://dx.doi.org/10.1002/ange.201812620.

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Asada-Kubota, M. "A monoclonal antibody specific for an epidermal cell antigen of Xenopus laevis: electron microscopic observations using a gold-labeling method." Journal of Histochemistry & Cytochemistry 36, no. 5 (1988): 515–21. http://dx.doi.org/10.1177/36.5.3356895.

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A monoclonal antibody (EPI-1), raised against the supernatant of a homogenate of Xenopus laevis larvae at the tailbud stage (stage 36/37), interacts specifically with a 250 KD epidermal antigen of Xenopus. An immunocytochemical gold-labeling technique was used to investigate changes in antigen distribution during epidermal development of Xenopus laevis. Specific immunolabeling was initially detected over the endoplasmic reticulum in the outer epithelial cells of the late gastrula stage (stage 12.5). After the early neurula stage (stage 13), immunolabeling appeared over moderately electron-dens
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Simorangkir, D. R., S. Ramaswamy, G. R. Marshall, R. Roslund, and T. M. Plant. "Sertoli cell differentiation in rhesus monkey (Macaca mulatta) is an early event in puberty and precedes attainment of the adult complement of undifferentiated spermatogonia." REPRODUCTION 143, no. 4 (2012): 513–22. http://dx.doi.org/10.1530/rep-11-0411.

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In primates, the time course of Sertoli cell proliferation and differentiation during puberty and its relationship with the expansion of undifferentiated type A spermatogonia that occurs at this critical stage of development are poorly defined. Mid and late juvenile and early and late pubertal male rhesus monkeys were studied. Testes were immersion fixed, embedded in paraffin, and sectioned at 5 μm. Sertoli cell number per testis, S-phase labeling (BrdU), and growth fraction (Ki67 labeling) were determined and correlated with corresponding parameters for undifferentiated type A spermatogonia (
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Dissertations / Theses on the topic "Late-stage labeling"

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Sardana, Malvika. "Development of New Late-Stage Labeling Methods with Labeled Carbon and Fluorine-18." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASF001.

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Le marquage isotopique est un outil précieux pour la découverte de nouveaux médicaments. Nous présentons dans cette thèse la conception et l’application de méthodes de marquage tardif de molécules bioactives avec du carbone et du fluor. Les réactions de carbonylation utilisant le monoxide de carbone sont connues pour être compatibles avec un marquage isotopique tardif des substances bioactives dans des conditions douces. La première partie de cette thèse décrit une réaction de photocarbonylation à partir d’iodures d’alkyles catalysée par le palladium sous lumière visible. Cette réaction polyva
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Wang, Wei. "Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://hdl.handle.net/21.11130/00-1735-0000-0005-14AE-1.

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Book chapters on the topic "Late-stage labeling"

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Edem, Patricia E., E. Johanna L. Steen, Andreas Kjær, and Matthias M. Herth. "Fluorine-18 Radiolabeling Strategies—Advantages and Disadvantages of Currently Applied Labeling Methods." In Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-812958-6.00002-1.

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