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1

Lulé, Dorothée, Albert C. Ludolph, and Andrea Kübler. Psychological morbidity in amyotrophic lateral sclerosis: Depression, anxiety, hopelessness. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757726.003.0003.

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Amyotrophic lateral sclerosis is a devastating condition with progressive loss of movement, speech, and respiratory function, and no available cure. Following the development of clinical symptoms and after receiving a diagnosis, patients may develop psychological morbidity, such as depression, anxiety, and hopelessness. However, many patients adjust successfully in the course of the disease and maintain good psychological well-being, so that a decline in psychological well-being does not necessarily accompany loss of physical function. There are several major determinants of good psychological adjustment to chronic and terminal disease—intrinsic factors such as coping strategies and internal locus of control, and extrinsic factors such as high (perceived and actual) social support by families and multidisciplinary professional teams. Providing care with a holistic view of the patient is probably the most effective approach to supporting patients’ psychosocial adjustment to the disease and minimizing depression, anxiety, and hopelessness.
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2

Herreros, Ivan. Learning and control. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0026.

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This chapter discusses basic concepts from control theory and machine learning to facilitate a formal understanding of animal learning and motor control. It first distinguishes between feedback and feed-forward control strategies, and later introduces the classification of machine learning applications into supervised, unsupervised, and reinforcement learning problems. Next, it links these concepts with their counterparts in the domain of the psychology of animal learning, highlighting the analogies between supervised learning and classical conditioning, reinforcement learning and operant conditioning, and between unsupervised and perceptual learning. Additionally, it interprets innate and acquired actions from the standpoint of feedback vs anticipatory and adaptive control. Finally, it argues how this framework of translating knowledge between formal and biological disciplines can serve us to not only structure and advance our understanding of brain function but also enrich engineering solutions at the level of robot learning and control with insights coming from biology.
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3

Godfrey, Barry, Pam Cox, Heather Shore, and Zoe Alker. After Care. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198788492.003.0007.

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Chapter 7 focuses on the experiences of the small minority who—to our knowledge—went on to become persistent offenders and often to experience lasting social exclusion. This group could be described as life course persistent offenders although it should be noted that there are many challenges in comparing ‘persistence’ across time and space. Significantly, this chapter asks whether the early life experiences of these ‘persisters’ (as documented in official sources) are markedly different from those of ‘desisters’. It finds little evidence setting the two groups apart. Thus it seems that early high risk profiles are not always accurate predictors of persistent offending; and that desistance tends to follow where individuals are supported by strong informal social controls to make wise choices, even later in life.
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4

Koskenniemi, Martti. Carl Schmitt and International Law. Edited by Jens Meierhenrich and Oliver Simons. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199916931.013.020.

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Carl Schmitt always presented himself and was above all a jurist. His doctoral dissertation was based on an antiformal theory of law that was also in evidence in his acerbic critics of the League of Nations and the system of control over Germany established in the Treaty of Versailles. This chapter shows that the concrete-order thinking of his later years espoused a more conventional legal realism that has always constituted an important stream of international jurisprudence. Schmitt’s main postwar work, Nomos der Erde, puts forward an influential view of the history of international law as inextricably entangled with the imperial pretensions. This chapter argues that the much-cited book, together with Schmitt’s polemical concept of law and his critiques of the discriminatory concept of war, has proven a fruitful basis for much of today’s postcolonial jurisprudence.
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5

Vernon, Martin J. Advance care planning for an ageing population. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198802136.003.0005.

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Population ageing is driven by declining fertility and improved life expectancy. As people survive to later life with multiple long-term conditions, advance care planning ACP) is of increasing importance to those wishing to retain control over their end-of-life care. Understanding disability trajectories for people can assist with advance care planning, mindful that older people living with frailty have increased risk of acute and unexpected health decline. Routine frailty identification by severity in older people can prompt care planning in anticipation of health decline and imminent lost capacity to make important decisions. Recognizing potential professional and organizational barriers to advance carer planning for older people could also improve its uptake. Guided serious illness conversations could assist this process over time for older people and those important to them. In care homes and among people with dementia ACP is also likely to be beneficial.
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6

Nguyen, Kim-Phuong, and Chris D. Glover. Anesthetic Considerations for Scoliosis Repair. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0032.

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Scoliosis is an anatomical deformity caused by a lateral and rotational shift in the thoracolumbar spine. Surgical correction involves wide exposure of the spine for placement of stabilizing rods and can result in significant complications from excessive blood loss and neurologic impairments. These procedures require vigilance to acid-base status, hemodynamic fluctuations, coagulation, temperature maintenance, and neurologic monitoring from anesthesiologists. Other major anesthetic considerations discussed include maintaining the integrity of perfusion to the spinal cord, positioning concerns, optimal technique for neuromonitoring, and pain control in the perioperative period. This chapter presents a case study of a 14-year-old girl with adolescent idiopathic scoliosis who presents for posterior spinal instrumentation and fusion from T4-L4 with autologous bone graft.
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7

Guthrie, Graeme. Narrowing the Gap. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780190641184.003.0004.

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Manager-shareholder conflict arises due to low levels of managerial ownership and the resulting wide separation of ownership and control. However, strong boards of directors can make even small ownership stakes more effective at motivating executives to work in shareholders’ best interests by granting stock options, repurchasing shares, and issuing debt. Ultimately they can approve a leveraged buyout, although a strong board is needed to overcome the conflicts of interest involved in management-led buyouts. This chapter uses events at HCA, the for-profit hospital chain that undertook the world’s largest leveraged buyout followed a few years later by the largest private equity IPO, to explain how boards can narrow the gap between ownership and control. It uses a novel representation of a firm’s capital structure to analyze the techniques for boosting ownership-generated incentives at relatively low cost to shareholders.
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8

Guillery, Ray. Thalamic higher-order driver inputs as sensorimotor links. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198806738.003.0009.

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This chapter provides a closer look at the branching patterns of driver inputs to higher-order thalamic nuclei, and introduces their functional significance for discussion in later chapters. Their thalamic branches bring information for relay to higher cortical levels, including a copy of the information carried in the motor branches about anticipated cortical contributions to the control of actions and consequent changes in perceptions. In this way, the cortex can add to the control of an action when there is a mismatch between action and perception. Most of these branched axons that have so far been described come from early sensory areas and only a few from other, higher areas have been studied. These branching inputs are a part of the hierarchy of cortical areas that provide an opportunity for higher areas to monitor lower areas and, when needed, contribute to the motor control of the phylogenetically older brainstem and spinal centres. A far more extensive review of the branched thalamic driver inputs and their contributions to the control of actions than we have at present will be crucial for understanding the full complexity of the thalamic relay.
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9

Venner, Anne, and Patrick M. Fuller. An overview of sleep–wake circuitry. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198778240.003.0005.

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How and when we wake and sleep are under the control of incredibly complex neural circuitry, consisting of neuronal populations (or nodes), neurotransmitters, and pathways that form orchestrated wake- or sleep-promoting networks. When any aspect of this neural circuitry is impaired (e.g. disease) or altered by external factors (e.g. stress), sleep and wake can be disrupted, sometimes quite profoundly. As one example, selective loss of orexin neurons in the lateral hypothalamus results in the sleep disorder narcolepsy. While our understanding of how discrete circuit elements in the brain work together to regulate wake and sleep remains incomplete, the relatively recent development of genetically driven tools and techniques has enabled a far more detailed understanding of the functional and structural basis of this circuitry. In this chapter, we review the current state of our understanding of the brain circuitry regulating sleep and wake, including how disruption of discrete circuit elements underlies a myriad of sleep- and wake-disorders.
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10

Elwood, Mark. Introduction. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199682898.003.0001.

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This chapter shows the plan of the book. Later chapters will cover the definition of causation, study designs that can demonstrate causation, how results are presented, the interpretation of studies stressing the non-causal explanations of observation bias, confounding, and chance variation. Then come positive aspects of causation, the Bradford-Hill principles, systematic reviews and meta-analyses, and an overall scheme for assessing studies and diagnosing causation. Further chapters present appraisals of six published studies: randomised trials, cohort studies, and case-control studies. An appendix presents statistical methods with examples.
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11

Levy, David. Presentation and early clinical course. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198766452.003.0002.

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The clinical importance of taking care with diagnostic terms for Type 1 diabetes and the need to avoid obsolete and confusing names. Clinical features at presentation of Type 1 diabetes, and features that differentiate it from later-onset autoimmune diabetes (LADA). The persistently high rate of presentation in diabetic ketoacidosis and its likely neuropsychiatric consequences. Key features of complex cases of DKA and current management strategies. The controversy over which subcutaneous insulin regimens to use after resolution of DKA. Definitions of and factors associated with partial remission (‘honeymoon’). Establishing good glycaemic control shortly after diagnosis probably preserves C-peptide levels.
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12

Carabin, Hélène, Maria V. Johansen, Jennifer F. Friedman, Stephen T. McGarvey, Henry Madsen, Zhou Xiao-Nong, and Steven Riley. Zoonotic schistosomosis (schistosomiasis). Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0062.

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Asiatic schistosomiosis is a very old disease with Schistosoma japonicum eggs found in human remains > 2000 years old from Hunan and Hubei provinces in China (Mao and Shao 1982). The original description of Asiatic schistosomiosis was made by Fujii in 1847 (Sasa 1972). The life cycle was fi rst described by Kawanashi (1904) who noted trematode-like eggs in cat faeces. The same year, Katsurada recovered adult worms from a cat from Katayama, Japan (Okabe 1964). Fujinami and Nakamura (1909) first reported skin infection with S. japonicum cercariae of different mammals, and Miyairi and Suzuki (1914) discovered that Oncomelania hupensis served as intermediate host where miracidia developed into sporocysts and further into cercariae (Jordan 2000). The snail hosts of S. japonicum were discovered in China by Faust and Meleney (1923), The Philippines by Tubangui (1932) and in Indonesia by Carvey et al. (1973). In addition to the skin as the principal route of infection, Suda (1924) described oral infection and several authors described the intrauterine route of infection. (Okabe 1964; Sasa 1972).Following the understanding of the lifecyle, control measures including wearing closely woven clothing, composting of faeces with urine for at least 14 days, replacing cattle with horses, killing of rodents especially rats, killing of snails by lime, copper sulphate or salt water, were proven to have some efficacy. In Japan, an effective integrated control programme started after Second World War with the last human case being reported in 1978 (Jordan 2000 ). The National Schistosomiosis Control Programme in China started in 1955 and at that time more than 10 million people were infected with S. japonicum (Wu 2002). Emetine and antimony potassium tartrate were among the first drugs with proven efficacy against schistosomiosis in humans. Later antimony and finally praziquantel and artemether have been introduced as highly effective drugs with only minor adverse effects (Wu 2002).
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13

Ing, Michael. The Vulnerability of Integrity in Early Confucian Thought. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780190679118.001.0001.

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The Vulnerability of Integrity in Early Confucian Thought is about the necessity, and even value, of vulnerability in human experience. In this book, Michael Ing brings early Chinese texts into dialogue with questions about the ways in which meaningful things are vulnerable to powers beyond our control; and more specifically, how relationships with meaningful others might compel tragic actions.Vulnerability is often understood as an undesirable state; and as such, invulnerability is preferred over vulnerability. While recognizing the need for adopting strategies of reducing vulnerability in various situations, The Vulnerability of Integrity demonstrates that vulnerability is far more enduring in human experience, and that it enables values such as morality, trust, and maturity. Vulnerability also highlights the need for care (care for oneself and for others). The possibility of tragic loss stresses the difficulty of offering and receiving care; and thereby fosters compassion for others as we strive to care for each other.This book is structured to explore the plurality of Confucian thought as it relates to the vulnerability of integrity. The first two chapters describe traditional and contemporary views that argue for the invulnerability of integrity in early Confucian thought. The remaining five chapters investigate alternative views. In particular these later chapters give attention to neglected voices in the tradition, which argue that our concern for others can, and even should, lead to us compromise our integrity. In these cases we are compelled to do something transgressive for the sake of others; and in these situations our integrity is jeopardized in the transgressive act.
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14

Anderson, James A. Programming. Oxford University Press, 2018. http://dx.doi.org/10.1093/acprof:oso/9780199357789.003.0014.

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The author makes several suggestions for how to control the direction taken by an active cognitive process. He proposes a neural/cognitive programming mechanism: traveling waves on cortex. Evidence for traveling waves exists, and interactions of such waves have useful properties. One example is due to Pitts and McCulloch: Why are squares of different sizes seen as examples of squares? If excitation propagates from the corners of a square, waves meet at the diagonals. Squares of different sizes then have a common diagonal representation. Later models include “grassfire models” and “medial axis” models. Experiments suggests that response exists at a “medial axis” halfway between bounding contours, and in this approach “Identity” and “Symmetry” become the same computation. Traveling waves in audition can be used to give the pattern-dependent frequency independent responses seen in some kinds of speech perception.
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15

Bross, Kristina. “Why should you be so furious?”. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190665135.003.0005.

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Chapter 4 focuses on the representation of Anglo-Dutch relations from Asia to America in the seventeenth century. The chapter analyzes the representation of an incident in 1623 on the spice island Amboyna when Dutch traders tortured (with waterboarding) and killed their English rivals in the East Indies. Decades later, New England writers returning to this incident, treating it as news, invoked anti-English violence half a world away to lay claim to a global English identity. The chapter compares visual representation of the Amboyna incident with John Underhill’s “figure” of the Mystic Fort massacre in New England, arguing that these representations of violence are key elements of colonial fantasies that made (and make) real atrocities possible. The coda discusses Stephen Bradwell’s 1633 first-aid manual, partly inspired by the Amboyna incident, which maintains that properly trained, authorized metropolitan authorities can control the potential dangers of the remedies torture and tobacco.
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16

Menon, Vinod. Arithmetic in the Child and Adult Brain. Edited by Roi Cohen Kadosh and Ann Dowker. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199642342.013.041.

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This review examines brain and cognitive processes involved in arithmetic. I take a distinctly developmental perspective because neither the cognitive nor the brain processes involved in arithmetic can be adequately understood outside the framework of how developmental processes unfold. I review four basic neurocognitive processes involved in arithmetic, highlighting (1) the role of core dorsal parietal and ventral temporal-occipital cortex systems that form basic building blocks from which number form and quantity representations are constructed in the brain; (2) procedural and working memory systems anchored in the basal ganglia and frontoparietal circuits, which create short-term representations that allow manipulation of multiple discrete quantities over several seconds; (3) episodic and semantic memory systems anchored in the medial and lateral temporal cortex that play an important role in long-term memory formation and generalization beyond individual problem attributes; and (4) prefrontal cortex control processes that guide allocation of attention resources and retrieval of facts from memory in the service of goal-directed problem solving. Next I examine arithmetic in the developing brain, first focusing on studies comparing arithmetic in children and adults, and then on studies examining development in children during critical stages of skill acquisition. I highlight neurodevelopmental models that go beyond parietal cortex regions involved in number processing, and demonstrate that brain systems and circuits in the developing child brain are clearly not the same as those seen in more mature adult brains sculpted by years of learning. The implications of these findings for a more comprehensive view of the neural basis of arithmetic in both children and adults are discussed.
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17

Conversi, Daniele. Cultural Homogenization, Ethnic Cleansing, and Genocide. Oxford University Press, 2017. http://dx.doi.org/10.1093/acrefore/9780190846626.013.139.

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Cultural homogenization is understood as a state-led policy aimed at cultural standardization and the overlap between state and culture. Homogeneity, however, is an ideological construct, presupposing the existence of a unified, organic community. It does not describe an actual phenomenon. Genocide and ethnic cleansing, meanwhile, can be described as a form of “social engineering” and radical homogenization. Together, these concepts can be seen as part of a continuum when considered as part of the process of state-building, where the goal has often been to forge cohesive, unified communities of citizens under governmental control. Homogenizing attempts can be traced as far back as ancient and medieval times, depending on how historians choose to approach the subject. Ideally, however, the history of systematic cultural homogenization begins at the French Revolution. With the French Revolution, the physical elimination of ideological-cultural opponents was pursued, together with a broader drive to “nationalize” the masses. This mobilizing-homogenizing thrust was widely shared by the usually fractious French revolutionary elites. Homogenization later peaked during the twentieth century, when state nationalism and its attendant politics emerged, resulting in a more coordinated, systematic approach toward cultural standardization. Nowadays, there are numerous methods to achieving homogenization, from interstate wars to forced migration and even to the more subtle shifts in the socio-political climate brought about by neoliberal globalization.
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18

Peretti, Daniel. Superman in Myth and Folklore. University Press of Mississippi, 2017. http://dx.doi.org/10.14325/mississippi/9781496814586.001.0001.

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Many artists draw upon folklore to craft films, music, literature, and other elements of popular culture. This book examines how the opposite phenomenon occurs: the use of popular culture in the expressive culture called folklore. Superman is an ideal focus for such as study because of his ubiquity. Though Superman is under the control of a corporation, fans nonetheless have developed a sense of ownership of him, often because of an affinity they feel toward him. Early chapters of this book explore the varieties of this affinity as experienced by individuals and as understood through interviews. Later chapters delve into specific events, such as the Superman Celebration in Illinois, and other modes of expression such as humor, personal narrative, and myth. Superman in Myth and Folklore explores the idea that a fictional character can be foundationally important in morality through fieldwork and interviews. In other words, fans use Superman to think through complex issues in their personal lives, and this book explores how. Despite the focus on fieldwork, there is some attention to the extant literature on Superman, ranging from educational works on science to psychology and history. There is also attention to the mythical aspects of Superman, with analyses of the character through several theories such as structuralism and functionalism. By examining jokes, festival, costuming, and narrative, this book explores the impact a fictional character can have.
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19

O’Connell, Sue. Lyme borreliosis. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0009.

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Lyme borreliosis is the most common vector-borne bacterial infection in the temperate northern hemisphere. In the United States of America over 35,000 confirmed or probable cases were reported by state health departments to the Centers for Disease Control and Prevention (CDC) in 2008. It is likely that well over 100,000 cases occur in Europe each year. Lyme borreliosis is caused by several genospecies of Borrelia burgdorferi sensu lato, which are transmitted by ticks of the Ixodes ricinus complex. The infection occurs most commonly in forested, woodland and heathland habitats that support the lifecycles of Ixodes ticks and the small mammals and birds that are reservoir-competent hosts for B burgorferi. The most common presenting feature of Lyme borreliosis is erythema migrans, a slowly spreading rash. The spirochaetes can disseminate through the bloodstream and lymphatics to other organs and tissues and cause later manifestations, most commonly affecting the nervous and musculoskeletal systems. The infection responds to appropriate antibiotic treatment at any stage of disease, with excellent outcomes in most cases, but patients with severe tissue damage from previously untreated late stage disease may recover incompletely. A small proportion of patients can have persistent non-specific symptoms following treatment, without evidence of continuing active infection. This has been termed “post-Lyme syndrome” and appears to be similar to other post-infection syndromes. Prevention relies mainly on personal protection measures against tick bites.
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Kendrisic, Mirjana, and Borislava Pujic. Endocrine and autoimmune disorders. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0047.

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Advanced maternal age and increasing numbers of women of childbearing age with endocrine and autoimmune disorders have become the challenge for both anaesthetists and obstetricians. Genetic studies have provided new insight into underlying causes of endocrine disorders and prenatal prediction of inheritance. The expression of endocrine disease may influence the interpretation of diagnostic laboratory testing during pregnancy. Better understanding of the pathophysiological mechanisms enables new therapeutic approaches which can compromise pregnancy outcome. Although only a small number of drugs have been shown through clinical studies to be safe for use in pregnancy, intensive therapy for chronic disease is usually needed. Thus, anaesthetic management of women with endocrine disorders in pregnancy has become more complex. The most frequently encountered endocrine disorders during pregnancy include gestational diabetes mellitus and thyroid and adrenal disorders. Gestational diabetes has become increasingly common in pregnant women. Not only does it influence pregnancy outcome, but it also carries a risk for mother and offspring of developing type 2 diabetes later in life. Intensive glucose control may prevent maternal and fetal complications and improve long-term outcome. Pregnancy itself has been found to influence the course of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. However, autoimmune diseases may have adverse consequences for maternal, fetal, and neonatal health. There is a relative paucity of literature concerning anaesthetic management of autoimmune diseases. Early recognition and immediate treatment of the common complications have been the key elements to achieving the ultimate goal—good pregnancy outcome.
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Miller, Nicholas R. Social Choice Theory and Legislative Institutions. Oxford University Press, 2016. http://dx.doi.org/10.1093/acrefore/9780190228637.013.1.

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This is an advance summary of a forthcoming article in the Oxford Research Encyclopedia of Politics. Please check back later for the full article.Narrowly understood, social choice theory is a specialized branch of applied logic and mathematics that analyzes abstract objects called preference aggregation functions, social welfare functions, and social choice functions. But more broadly, social choice theory identifies, analyzes, and evaluates rules that may be used to make collective decisions. So understood, social choice is a subfield of the social sciences that examines what may be called “voting rules” of various sorts. While social choice theory typically assumes a finite set of alternatives over which voter preferences are unrestricted, the spatial model of social choice assumes that policy alternatives can be represented by points in a space of one or more dimensions, and that voters have preferences that are plausibly shaped by this spatial structure.Social choice theory has considerable relevance for the study of legislative (as well as electoral) institutions. The concepts and tools of social choice theory make possible formal descriptions of legislative institutions such as bicameralism, parliamentary voting procedures, effects of decision rules (e.g., supramajority vs. simple majority rule and executive veto rules), sincere vs. strategic voting by legislators, agenda control, and other parliamentary maneuvers. Spatial models of social choice further enrich this analysis and raise additional questions regarding policy stability and change. Spatial models are used increasingly to guide empirical research on legislative institutions and processes.
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22

Pipitone, Nicolò, Annibale Versari, and Carlo Salvarani. Large-vessel vasculitis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0133.

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Large-vessel vasculitis includes giant cell arteritis (GCA) and Takayasu's arteritis (TAK). GCA affects patients aged over 50, mainly of white European ethnicity. GCA occurs together with polymyalgia rheumatica (PMR) more frequently than expected by chance. In both conditions, females are affected two to three times more often than males. GCA mainly involves large- and medium-sized arteries, particularly the branches of the proximal aorta including the temporal arteries. Vasculitic involvement results in the typical manifestations of GCA including temporal headache, jaw claudication, and visual loss. A systemic inflammatory response and a marked response to glucocorticoids is characteristic of GCA. GCA usually remits within 6 months to 2 years from disease onset. However, some patients have a chronic-relapsing course and may require long-standing treatment. Mortality is not increased, but there is significant morbidity mainly related to chronic glucocorticoid use and cranial ischaemic events, especially visual loss. The diagnosis of GCA rests on the characteristic clinical features and raised inflammatory markers, but temporal artery biopsy remains the gold standard to support the clinical suspicion. Imaging techniques are also used to demonstrate large-vessel involvement in GCA. Glucocorticoids are the mainstay of treatment for GCA, but other therapeutic approaches have been proposed and novel ones are being developed. TAK mainly involves the aorta and its main branches. Women are particularly affected with a female:male ratio of 9:1. In most patients, age of onset is between 20 and 30 years. Early manifestations of TAK are non-specific and include constitutional and musculoskeletal symptoms. Later on, vascular complications become manifest. Most patients develop vessel stenoses, particularly in the branches of the aortic artery, leading to manifestations of vascular hypoperfusion. Aneurysms occur in a minority of cases. There are no specific laboratory tests to diagnose TAK, although most patients have raised inflammatory markers, therefore, imaging techniques are required to secure the diagnosis. Glucocorticoids are the mainstay of treatment of TAK. However, many patients have an insufficient response to glucocorticoids alone, or relapse when they are tapered or discontinued. Immunosuppressive agents and, in refractory cases, biological drugs can often attain disease control and prevent vascular complications. Revascularization procedures are required in patients with severe established stenoses or occlusions.
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23

Pipitone, Nicolò, Annibale Versari, and Carlo Salvarani. Large-vessel vasculitis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642489.003.0133_update_003.

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Large-vessel vasculitis includes giant cell arteritis (GCA) and Takayasu’s arteritis (TAK). GCA affects patients aged over 50, mainly of white European ethnicity. GCA occurs together with polymyalgia rheumatica (PMR) more frequently than expected by chance. In both conditions, females are affected two to three times more often than males. GCA mainly involves large- and medium-sized arteries, particularly the branches of the proximal aorta including the temporal arteries. Vasculitic involvement results in the typical manifestations of GCA including temporal headache, jaw claudication, and visual loss. A systemic inflammatory response and a marked response to glucocorticoids is characteristic of GCA. GCA usually remits within 6 months to 2 years from disease onset. However, some patients have a chronic-relapsing course and may require longstanding treatment. Mortality is not increased, but there is significant morbidity mainly related to chronic glucocorticoid use and cranial ischaemic events, especially visual loss. The diagnosis of GCA rests on the characteristic clinical features and raised inflammatory markers, but temporal artery biopsy remains the gold standard to support the clinical suspicion. Imaging techniques are also used to demonstrate large-vessel involvement in GCA. Glucocorticoids are the mainstay of treatment for GCA, but other therapeutic approaches have been proposed and novel ones are being developed. TAK mainly involves the aorta and its main branches. Women are particularly affected with a female:male ratio of 9:1. In most patients, age of onset is between 20 and 30 years. Early manifestations of TAK are non-specific and include constitutional and musculoskeletal symptoms. Later on, vascular complications become manifest. Most patients develop vessel stenoses, particularly in the branches of the aortic artery, leading to manifestations of vascular hypoperfusion. Aneurysms occur in a minority of cases. There are no specific laboratory tests to diagnose TAK, although most patients have raised inflammatory markers, therefore, imaging techniques are required to secure the diagnosis. Glucocorticoids are the mainstay of treatment of TAK. However, many patients have an insufficient response to glucocorticoids alone, or relapse when they are tapered or discontinued. Immunosuppressive agents and, in refractory cases, biological drugs can often attain disease control and prevent vascular complications. Revascularization procedures are required in patients with severe established stenoses or occlusions.
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24

Johansen, Bruce, and Adebowale Akande, eds. Nationalism: Past as Prologue. Nova Science Publishers, Inc., 2021. http://dx.doi.org/10.52305/aief3847.

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Abstract:
Nationalism: Past as Prologue began as a single volume being compiled by Ad Akande, a scholar from South Africa, who proposed it to me as co-author about two years ago. The original idea was to examine how the damaging roots of nationalism have been corroding political systems around the world, and creating dangerous obstacles for necessary international cooperation. Since I (Bruce E. Johansen) has written profusely about climate change (global warming, a.k.a. infrared forcing), I suggested a concerted effort in that direction. This is a worldwide existential threat that affects every living thing on Earth. It often compounds upon itself, so delays in reducing emissions of fossil fuels are shortening the amount of time remaining to eliminate the use of fossil fuels to preserve a livable planet. Nationalism often impedes solutions to this problem (among many others), as nations place their singular needs above the common good. Our initial proposal got around, and abstracts on many subjects arrived. Within a few weeks, we had enough good material for a 100,000-word book. The book then fattened to two moderate volumes and then to four two very hefty tomes. We tried several different titles as good submissions swelled. We also discovered that our best contributors were experts in their fields, which ranged the world. We settled on three stand-alone books:” 1/ nationalism and racial justice. Our first volume grew as the growth of Black Lives Matter following the brutal killing of George Floyd ignited protests over police brutality and other issues during 2020, following the police assassination of Floyd in Minneapolis. It is estimated that more people took part in protests of police brutality during the summer of 2020 than any other series of marches in United States history. This includes upheavals during the 1960s over racial issues and against the war in Southeast Asia (notably Vietnam). We choose a volume on racism because it is one of nationalism’s main motive forces. This volume provides a worldwide array of work on nationalism’s growth in various countries, usually by authors residing in them, or in the United States with ethnic ties to the nation being examined, often recent immigrants to the United States from them. Our roster of contributors comprises a small United Nations of insightful, well-written research and commentary from Indonesia, New Zealand, Australia, China, India, South Africa, France, Portugal, Estonia, Hungary, Russia, Poland, Kazakhstan, Georgia, and the United States. Volume 2 (this one) describes and analyzes nationalism, by country, around the world, except for the United States; and 3/material directly related to President Donald Trump, and the United States. The first volume is under consideration at the Texas A & M University Press. The other two are under contract to Nova Science Publishers (which includes social sciences). These three volumes may be used individually or as a set. Environmental material is taken up in appropriate places in each of the three books. * * * * * What became the United States of America has been strongly nationalist since the English of present-day Massachusetts and Jamestown first hit North America’s eastern shores. The country propelled itself across North America with the self-serving ideology of “manifest destiny” for four centuries before Donald Trump came along. Anyone who believes that a Trumpian affection for deportation of “illegals” is a new thing ought to take a look at immigration and deportation statistics in Adam Goodman’s The Deportation Machine: America’s Long History of Deporting Immigrants (Princeton University Press, 2020). Between 1920 and 2018, the United States deported 56.3 million people, compared with 51.7 million who were granted legal immigration status during the same dates. Nearly nine of ten deportees were Mexican (Nolan, 2020, 83). This kind of nationalism, has become an assassin of democracy as well as an impediment to solving global problems. Paul Krugman wrote in the New York Times (2019:A-25): that “In their 2018 book, How Democracies Die, the political scientists Steven Levitsky and Daniel Ziblatt documented how this process has played out in many countries, from Vladimir Putin’s Russia, to Recep Erdogan’s Turkey, to Viktor Orban’s Hungary. Add to these India’s Narendra Modi, China’s Xi Jinping, and the United States’ Donald Trump, among others. Bit by bit, the guardrails of democracy have been torn down, as institutions meant to serve the public became tools of ruling parties and self-serving ideologies, weaponized to punish and intimidate opposition parties’ opponents. On paper, these countries are still democracies; in practice, they have become one-party regimes….And it’s happening here [the United States] as we speak. If you are not worried about the future of American democracy, you aren’t paying attention” (Krugmam, 2019, A-25). We are reminded continuously that the late Carl Sagan, one of our most insightful scientific public intellectuals, had an interesting theory about highly developed civilizations. Given the number of stars and planets that must exist in the vast reaches of the universe, he said, there must be other highly developed and organized forms of life. Distance may keep us from making physical contact, but Sagan said that another reason we may never be on speaking terms with another intelligent race is (judging from our own example) could be their penchant for destroying themselves in relatively short order after reaching technological complexity. This book’s chapters, introduction, and conclusion examine the worldwide rise of partisan nationalism and the damage it has wrought on the worldwide pursuit of solutions for issues requiring worldwide scope, such scientific co-operation public health and others, mixing analysis of both. We use both historical description and analysis. This analysis concludes with a description of why we must avoid the isolating nature of nationalism that isolates people and encourages separation if we are to deal with issues of world-wide concern, and to maintain a sustainable, survivable Earth, placing the dominant political movement of our time against the Earth’s existential crises. Our contributors, all experts in their fields, each have assumed responsibility for a country, or two if they are related. This work entwines themes of worldwide concern with the political growth of nationalism because leaders with such a worldview are disinclined to co-operate internationally at a time when nations must find ways to solve common problems, such as the climate crisis. Inability to cooperate at this stage may doom everyone, eventually, to an overheated, stormy future plagued by droughts and deluges portending shortages of food and other essential commodities, meanwhile destroying large coastal urban areas because of rising sea levels. Future historians may look back at our time and wonder why as well as how our world succumbed to isolating nationalism at a time when time was so short for cooperative intervention which is crucial for survival of a sustainable earth. Pride in language and culture is salubrious to individuals’ sense of history and identity. Excess nationalism that prevents international co-operation on harmful worldwide maladies is quite another. As Pope Francis has pointed out: For all of our connectivity due to expansion of social media, ability to communicate can breed contempt as well as mutual trust. “For all our hyper-connectivity,” said Francis, “We witnessed a fragmentation that made it more difficult to resolve problems that affect us all” (Horowitz, 2020, A-12). The pope’s encyclical, titled “Brothers All,” also said: “The forces of myopic, extremist, resentful, and aggressive nationalism are on the rise.” The pope’s document also advocates support for migrants, as well as resistance to nationalist and tribal populism. Francis broadened his critique to the role of market capitalism, as well as nationalism has failed the peoples of the world when they need co-operation and solidarity in the face of the world-wide corona virus pandemic. Humankind needs to unite into “a new sense of the human family [Fratelli Tutti, “Brothers All”], that rejects war at all costs” (Pope, 2020, 6-A). Our journey takes us first to Russia, with the able eye and honed expertise of Richard D. Anderson, Jr. who teaches as UCLA and publishes on the subject of his chapter: “Putin, Russian identity, and Russia’s conduct at home and abroad.” Readers should find Dr. Anderson’s analysis fascinating because Vladimir Putin, the singular leader of Russian foreign and domestic policy these days (and perhaps for the rest of his life, given how malleable Russia’s Constitution has become) may be a short man physically, but has high ambitions. One of these involves restoring the old Russian (and Soviet) empire, which would involve re-subjugating a number of nations that broke off as the old order dissolved about 30 years ago. President (shall we say czar?) Putin also has international ambitions, notably by destabilizing the United States, where election meddling has become a specialty. The sight of Putin and U.S. president Donald Trump, two very rich men (Putin $70-$200 billion; Trump $2.5 billion), nuzzling in friendship would probably set Thomas Jefferson and Vladimir Lenin spinning in their graves. The road of history can take some unanticipated twists and turns. Consider Poland, from which we have an expert native analysis in chapter 2, Bartosz Hlebowicz, who is a Polish anthropologist and journalist. His piece is titled “Lawless and Unjust: How to Quickly Make Your Own Country a Puppet State Run by a Group of Hoodlums – the Hopeless Case of Poland (2015–2020).” When I visited Poland to teach and lecture twice between 2006 and 2008, most people seemed to be walking on air induced by freedom to conduct their own affairs to an unusual degree for a state usually squeezed between nationalists in Germany and Russia. What did the Poles then do in a couple of decades? Read Hlebowicz’ chapter and decide. It certainly isn’t soft-bellied liberalism. In Chapter 3, with Bruce E. Johansen, we visit China’s western provinces, the lands of Tibet as well as the Uighurs and other Muslims in the Xinjiang region, who would most assuredly resent being characterized as being possessed by the Chinese of the Han to the east. As a student of Native American history, I had never before thought of the Tibetans and Uighurs as Native peoples struggling against the Independence-minded peoples of a land that is called an adjunct of China on most of our maps. The random act of sitting next to a young woman on an Air India flight out of Hyderabad, bound for New Delhi taught me that the Tibetans had something to share with the Lakota, the Iroquois, and hundreds of other Native American states and nations in North America. Active resistance to Chinese rule lasted into the mid-nineteenth century, and continues today in a subversive manner, even in song, as I learned in 2018 when I acted as a foreign adjudicator on a Ph.D. dissertation by a Tibetan student at the University of Madras (in what is now in a city called Chennai), in southwestern India on resistance in song during Tibet’s recent history. Tibet is one of very few places on Earth where a young dissident can get shot to death for singing a song that troubles China’s Quest for Lebensraum. The situation in Xinjiang region, where close to a million Muslims have been interned in “reeducation” camps surrounded with brick walls and barbed wire. They sing, too. Come with us and hear the music. Back to Europe now, in Chapter 4, to Portugal and Spain, we find a break in the general pattern of nationalism. Portugal has been more progressive governmentally than most. Spain varies from a liberal majority to military coups, a pattern which has been exported to Latin America. A situation such as this can make use of the term “populism” problematic, because general usage in our time usually ties the word into a right-wing connotative straightjacket. “Populism” can be used to describe progressive (left-wing) insurgencies as well. José Pinto, who is native to Portugal and also researches and writes in Spanish as well as English, in “Populism in Portugal and Spain: a Real Neighbourhood?” provides insight into these historical paradoxes. Hungary shares some historical inclinations with Poland (above). Both emerged from Soviet dominance in an air of developing freedom and multicultural diversity after the Berlin Wall fell and the Soviet Union collapsed. Then, gradually at first, right wing-forces began to tighten up, stripping structures supporting popular freedom, from the courts, mass media, and other institutions. In Chapter 5, Bernard Tamas, in “From Youth Movement to Right-Liberal Wing Authoritarianism: The Rise of Fidesz and the Decline of Hungarian Democracy” puts the renewed growth of political and social repression into a context of worldwide nationalism. Tamas, an associate professor of political science at Valdosta State University, has been a postdoctoral fellow at Harvard University and a Fulbright scholar at the Central European University in Budapest, Hungary. His books include From Dissident to Party Politics: The Struggle for Democracy in Post-Communist Hungary (2007). Bear in mind that not everyone shares Orbán’s vision of what will make this nation great, again. On graffiti-covered walls in Budapest, Runes (traditional Hungarian script) has been found that read “Orbán is a motherfucker” (Mikanowski, 2019, 58). Also in Europe, in Chapter 6, Professor Ronan Le Coadic, of the University of Rennes, Rennes, France, in “Is There a Revival of French Nationalism?” Stating this title in the form of a question is quite appropriate because France’s nationalistic shift has built and ebbed several times during the last few decades. For a time after 2000, it came close to assuming the role of a substantial minority, only to ebb after that. In 2017, the candidate of the National Front reached the second round of the French presidential election. This was the second time this nationalist party reached the second round of the presidential election in the history of the Fifth Republic. In 2002, however, Jean-Marie Le Pen had only obtained 17.79% of the votes, while fifteen years later his daughter, Marine Le Pen, almost doubled her father's record, reaching 33.90% of the votes cast. Moreover, in the 2019 European elections, re-named Rassemblement National obtained the largest number of votes of all French political formations and can therefore boast of being "the leading party in France.” The brutality of oppressive nationalism may be expressed in personal relationships, such as child abuse. While Indonesia and Aotearoa [the Maoris’ name for New Zealand] hold very different ranks in the United Nations Human Development Programme assessments, where Indonesia is classified as a medium development country and Aotearoa New Zealand as a very high development country. In Chapter 7, “Domestic Violence Against Women in Indonesia and Aotearoa New Zealand: Making Sense of Differences and Similarities” co-authors, in Chapter 8, Mandy Morgan and Dr. Elli N. Hayati, from New Zealand and Indonesia respectively, found that despite their socio-economic differences, one in three women in each country experience physical or sexual intimate partner violence over their lifetime. In this chapter ther authors aim to deepen understandings of domestic violence through discussion of the socio-economic and demographic characteristics of theit countries to address domestic violence alongside studies of women’s attitudes to gender norms and experiences of intimate partner violence. One of the most surprising and upsetting scholarly journeys that a North American student may take involves Adolf Hitler’s comments on oppression of American Indians and Blacks as he imagined the construction of the Nazi state, a genesis of nationalism that is all but unknown in the United States of America, traced in this volume (Chapter 8) by co-editor Johansen. Beginning in Mein Kampf, during the 1920s, Hitler explicitly used the westward expansion of the United States across North America as a model and justification for Nazi conquest and anticipated colonization by Germans of what the Nazis called the “wild East” – the Slavic nations of Poland, the Baltic states, Ukraine, and Russia, most of which were under control of the Soviet Union. The Volga River (in Russia) was styled by Hitler as the Germans’ Mississippi, and covered wagons were readied for the German “manifest destiny” of imprisoning, eradicating, and replacing peoples the Nazis deemed inferior, all with direct references to events in North America during the previous century. At the same time, with no sense of contradiction, the Nazis partook of a long-standing German romanticism of Native Americans. One of Goebbels’ less propitious schemes was to confer honorary Aryan status on Native American tribes, in the hope that they would rise up against their oppressors. U.S. racial attitudes were “evidence [to the Nazis] that America was evolving in the right direction, despite its specious rhetoric about equality.” Ming Xie, originally from Beijing, in the People’s Republic of China, in Chapter 9, “News Coverage and Public Perceptions of the Social Credit System in China,” writes that The State Council of China in 2014 announced “that a nationwide social credit system would be established” in China. “Under this system, individuals, private companies, social organizations, and governmental agencies are assigned a score which will be calculated based on their trustworthiness and daily actions such as transaction history, professional conduct, obedience to law, corruption, tax evasion, and academic plagiarism.” The “nationalism” in this case is that of the state over the individual. China has 1.4 billion people; this system takes their measure for the purpose of state control. Once fully operational, control will be more subtle. People who are subject to it, through modern technology (most often smart phones) will prompt many people to self-censor. Orwell, modernized, might write: “Your smart phone is watching you.” Ming Xie holds two Ph.Ds, one in Public Administration from University of Nebraska at Omaha and another in Cultural Anthropology from the Chinese Academy of Social Sciences, Beijing, where she also worked for more than 10 years at a national think tank in the same institution. While there she summarized news from non-Chinese sources for senior members of the Chinese Communist Party. Ming is presently an assistant professor at the Department of Political Science and Criminal Justice, West Texas A&M University. In Chapter 10, analyzing native peoples and nationhood, Barbara Alice Mann, Professor of Honours at the University of Toledo, in “Divide, et Impera: The Self-Genocide Game” details ways in which European-American invaders deprive the conquered of their sense of nationhood as part of a subjugation system that amounts to genocide, rubbing out their languages and cultures -- and ultimately forcing the native peoples to assimilate on their own, for survival in a culture that is foreign to them. Mann is one of Native American Studies’ most acute critics of conquests’ contradictions, and an author who retrieves Native history with a powerful sense of voice and purpose, having authored roughly a dozen books and numerous book chapters, among many other works, who has traveled around the world lecturing and publishing on many subjects. Nalanda Roy and S. Mae Pedron in Chapter 11, “Understanding the Face of Humanity: The Rohingya Genocide.” describe one of the largest forced migrations in the history of the human race, the removal of 700,000 to 800,000 Muslims from Buddhist Myanmar to Bangladesh, which itself is already one of the most crowded and impoverished nations on Earth. With about 150 million people packed into an area the size of Nebraska and Iowa (population less than a tenth that of Bangladesh, a country that is losing land steadily to rising sea levels and erosion of the Ganges river delta. The Rohingyas’ refugee camp has been squeezed onto a gigantic, eroding, muddy slope that contains nearly no vegetation. However, Bangladesh is majority Muslim, so while the Rohingya may starve, they won’t be shot to death by marauding armies. Both authors of this exquisite (and excruciating) account teach at Georgia Southern University in Savannah, Georgia, Roy as an associate professor of International Studies and Asian politics, and Pedron as a graduate student; Roy originally hails from very eastern India, close to both Myanmar and Bangladesh, so he has special insight into the context of one of the most brutal genocides of our time, or any other. This is our case describing the problems that nationalism has and will pose for the sustainability of the Earth as our little blue-and-green orb becomes more crowded over time. The old ways, in which national arguments often end in devastating wars, are obsolete, given that the Earth and all the people, plants, and other animals that it sustains are faced with the existential threat of a climate crisis that within two centuries, more or less, will flood large parts of coastal cities, and endanger many species of plants and animals. To survive, we must listen to the Earth, and observe her travails, because they are increasingly our own.
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