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Dissertations / Theses on the topic 'Lateral geniculate nucleus (LGN)'

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1

Williams, Adrian Lloyd. "Growth dynamics in the developing lateral geniculate nucleus." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313613.

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2

Webb, Ben Sebastian. "Extra-classical receptive field mechanisms in the lateral geniculate nucleus." Thesis, University of Nottingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275162.

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3

Tang, Jiaying. "Characterization of response properties in the mouse lateral geniculate nucleus." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/28098.

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The lateral geniculate nucleus (LGN) has been increasingly recognized to actively regulate information transmission to primary visual cortex (V1). Although efforts have been devoted to study its morphological and functional features, the full array of response characteristics in mouse LGN as well as their dependency on subjective state have been relatively unexplored. To address the question we recorded from mouse LGN with multisite-electrode-arrays (MEAs). From a dataset with 185 single units, our results revealed several exceptional response features in mouse LGN. We also demonstrated that s
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4

Leiwe, Marcus. "Three dimensional organisation of the adult mouse dorsal Lateral Geniculate Nucleus." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/three-dimensional-organisation-of-the-adult-mouse-dorsal-lateral-geniculate-nucleus(9abe5868-cf4e-4968-adf8-0bb885be040d).html.

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The dLGN (dorsal Lateral Geniculate Nucleus) is the gateway to cortical processing for visual information encoded by RGCs (retinal ganglion cells). Owing to advances in genetic manipulations, the mouse is increasingly the model system of choice for understanding the function and organisation of the visual system. However the mouse dLGN has not been thoroughly investigated anatomically due to its difficult topology and location in the brain. We addressed this issue by indentifying the best reconstruction paradigm for recovering the true 3D shape of the dLGN from serial histological sections. We
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5

Brody, Carlos Hopfield John J. Hopfield John J. "Analysis and modeling of spike train correlations in the lateral geniculate nucleus /." Diss., Pasadena, Calif. : California Institute of Technology, 1998. http://resolver.caltech.edu/CaltechETD:etd-01182008-092108.

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6

Seabrook, Tania. "Circuit Development in the Dorsal Lateral Geniculate Nucleus (dLGN) of the Mouse." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/304.

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The visual system is one of the most widely used and best understood sensory systems and the dorsal lateral geniculate nucleus (dLGN) of the mouse has emerged as a model for investigating the cellular and molecular mechanisms underlying the development and activity-dependent refinement of sensory connections. Thalamic organization is highly conserved throughout species and the dLGN of the mouse possesses many features common to higher mammals, such as carnivores and primates. Two general classes of neuron are present within the dLGN, thalamocortical relay cells and interneurons, both of which
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7

Denning, Kate. "Effects of non-linear processing on information transfer in the lateral geniculate nucleus." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2006. http://wwwlib.umi.com/cr/ucsd/fullcit?p3214744.

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Thesis (Ph. D.)--University of California, San Diego, 2006.<br>Title from first page of PDF file (viewed July 21, 2006). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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8

Li, Ziwen. "Role of transcription factor Pax6 in the development of the ventral lateral geniculate nucleus." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31403.

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The development of the diencephalon can be summarised as a process in which cells that initially appear similar give rise to a complex structure that contains a variety of cell groups called nuclei. It involves two stages: the early patterning of the diencephalic prosomeres and the later formation of the individual nuclei. It has been shown that transcription factors and morphogens regulate the first stage but their further effects on the second stage remain unclear. The ventral lateral geniculate nucleus (vLGN) is involved in the visual system and is shown to have complex origins from the tha
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9

Guarino, Domenico Giulio. "Functional roles of the corticothalamic feedback loop." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=1971&f=13868.

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Le thalamus visuel dorsal des vertébrés reçoit des projections de rétroaction du cortex visuel primaire (V1) qui dépassent largement en densité de connexion la projection directe, que ce soit au niveau du thalamus ou du cortex. De nombreux travaux expérimentaux et de modélisation ont été consacrés à l'étude en boucle ouverte des projections « feedforward » reliant la rétine, le thalamus et le cortex. Mais la relative paucité des conditions expérimentales et leur absence d'homogénéité et de contrôle paramétrique, le manque de reproductibilité des observations fonctionnelles et les données struc
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10

Monavarfeshani, Aboozar. "Mechanisms underlying retinogeniculate synapse formation in mouse visual thalamus." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/81893.

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Retinogeniculate (RG) synapses connect retinal ganglion cells to the thalamic relay cells of the dorsal lateral geniculate nucleus (dLGN). They are critical for regulating the flow of visual information from retina to primary visual cortex (V1). RG synapses in dLGN are uniquely larger and stronger than their counterparts in other retinorecipient regions. Moreover, in dLGN, RG synapses can be classified into two groups: simple RG synapses, which contain glia-encapsulated single RTs synapsing onto relay cell dendrites, and complex RG synapses, which contain numerous RTs that converge onto the s
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11

Esguerra, Manuel. "Synaptic transmission in the ferret lateral geniculate nucleus in vitro : modulation by membrane voltage and neurotransmitters." Thesis, Massachusetts Institute of Technology, 1991. http://hdl.handle.net/1721.1/13954.

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12

Lynch, R. C. J. "The functional and pharmacological organisation of neurones in lamina C of the feline dorsal lateral geniculate nucleus." Thesis, Bucks New University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384629.

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13

Hitz, Sherri Lynn 1970. "Postnatal development of brainstem cholinergic inputs to the dorsal lateral geniculate nucleus of the domesticated ferret, Mustela putorius furo." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/9676.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1998.<br>Includes bibliographical references (p. 45-46).<br>The ferret dorsal lateral geniculate nucleus (dLGN) undergoes two periods of retinal afferent segregation during postnatal development. The first establishes the eye-specific laminae, A and A 1, and the second establishes ON/OFF sublaminae within laminae A and At. In contrast to eyespecific segregation, which seems to rely only on presynaptic activity, ON /OFF sublamination requires both pre- and postsynaptic activity. Because of its dependenc
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14

El-Danaf, Rana. "DEVELOPMENTAL REMODELING OF RELAY CELLS IN THE DORSAL LATERAL GENICULATE NUCLEUS (dLGN) OF THE MOUSE AND THE ROLE OF RETINAL INNERVATION." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/267.

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The dorsal lateral geniculate nucleus (dLGN) has become an important model for studying many aspects of visual system development. To date, studies have focused on the development of retinal projections and the role of activity in shaping the pattern of synaptic connections made with thalamocortical relay cells. By contrast, little is known about relay cells and the factors that regulate the growth and establishment of their dendritic architecture. In many systems, such growth seems consistent with the synaptotrophic hypothesis which states that synapse formation and dendritic growth work in
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15

Kogan, Cary. "The expression of neurofilament protein and mRNA levels in the lateral geniculate nucleus and area V1 of the developing and adult vervet monkey (Ceorcopithicus aethiops) /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0028/MQ50807.pdf.

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16

Gabbott, P. L. A. "Quantitative neurohistological correlates of visual deprivation in the visual system of the rat and GABA immunocytochemistry of the rat cerebellum and dorsal lateral geniculate nucleus." Thesis, Open University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354999.

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17

Morhardt, Duncan. "Influence of retinal states on the development and maintenance of retinofugal projections." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/111.

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Vision provides a critical interface with the physical world. This work examines visual development and vision loss in mice to glean the influence of the retinal state on visual connections. I first assessed the impact of retinal activity on the eye-specific segregation of retinal afferents in the lateral geniculate nucleus (LGN) of young Gβ5 -/- mice. Gβ5 is the fifth member of the β subfamily of heterotrimeric G proteins. Gβ5 binds and stabilizes the R7 family of regulators of G-protein signaling (RGS), which accelerate Gi/o GTP hydrolysis. Gβ5 -/- mice, which lack R7RGS activity, have malfo
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18

Haner, Cheryl. "Novel Roles for Reelin in Retinogeniculate Targeting." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2233.

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In the developing visual system, the axon of a pre-synaptic cell must be guided to a post-synaptic partner. Retinal ganglion cells (RGCs) in the eye are an excellent model to study this process. Multiple classes exist that respond to specific types of light input, and these project to different destinations in the brain that process distinct types of information. The RGC axons that navigate to the lateral geniculate nucleus (LGN) do so in a class-specific manner. Axons from RGCs that mediate non-image forming functions innervate the ventral LGN (vLGN) and the intergeniculate leaflet (IGL). Ax
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19

Tang-Wright, Kimmy. "Visual topography and perceptual learning in the primate visual system." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:388b9658-dceb-443a-a19b-c960af162819.

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The primate visual system is organised and wired in a topological manner. From the eye well into extrastriate visual cortex, a preserved spatial representation of the vi- sual world is maintained across many levels of processing. Diffusion-weighted imaging (DWI), together with probabilistic tractography, is a non-invasive technique for map- ping connectivity within the brain. In this thesis I probed the sensitivity and accuracy of DWI and probabilistic tractography by quantifying its capacity to detect topolog- ical connectivity in the post mortem macaque brain, between the lateral geniculate
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20

Borda, Janaina Siqueira. "O N?cleo genu?no lateral dorsal do t?lamo do sag?i (callithrix jacchus): Pproje??o retiniana, caracteriza??o citoarquitet?nica e neuroquimica da principal esta??o visual prim?ria." Universidade Federal do Rio Grande do Norte, 2009. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17288.

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Made available in DSpace on 2014-12-17T15:36:57Z (GMT). No. of bitstreams: 1 JanainaSB.pdf: 2453259 bytes, checksum: d4ce3e2bc8b59c2bee9fa61810a98832 (MD5) Previous issue date: 2009-10-29<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>The thalamus plays an important role in the sensorial processing information, in this particular case, the visual information. Several neuronal groups have been characterized as conductors and processors of important sensorial information to the cerebral cortex. The lateral geniculate complex is one to them, and appears as a group very stud
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21

Prieur, Delphine. "Nouveau rôle de la Sémaphorine 6D et de son récepteur Plexine-A1 dans le ciblage des axones rétiniens." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS285/document.

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Durant le développement, l’innervation d’une zone précise du cerveau par certaines branches axonales est un mécanisme encore mal compris. Afin d’aborder cette question, je me suis intéressée aux axones rétiniens qui innervent deux cibles principales du système visuel : le corps genouillé latéral dorsal (CGLd) et le colliculus supérieur. J’ai étudié le rôle de la protéine de guidage Sémaphorine 6D et de son récepteur Plexine-A1 dans l’innervation spécifique du CGLd par les axones rétiniens. J’ai ainsi découvert que chez les souris Sema6D-/- et Plexine-A1-/-, le tractus optique (formé par les ax
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22

(8086100), Samuel T. Kissinger. "Visual experience-dependent oscillations in the mouse visual system." Thesis, 2019.

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<p><a></a><a>The visual system is capable of interpreting immense sensory complexity, allowing us to quickly identify behaviorally relevant stimuli in the environment. It performs this task with a hierarchical organization that works to detect, relay, and integrate visual stimulus features into an interpretable form. To understand the complexities of this system, visual neuroscientists have benefited from the many advantages of using mice as visual models. Despite their poor visual acuity, these animals possess surprisingly complex visual systems, and have been instrumental in understanding ho
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23

Brody, Carlos D. "Analysis and modeling of spike train correlations in the lateral geniculate nucleus." Thesis, 1998. https://thesis.library.caltech.edu/222/1/Brody_cd_1998.pdf.

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In this thesis I consider the cross-correlation analysis of spike train data, in two parts. In the first part, I consider the question of the proper interpretation of peaks in covariograms: It is known that peaks in the covariogram of the spike trains of two cells are due to covariations, not time-locked to the stimulus, in the responses of the two cells. Such peaks, even when they have widths on the order of 10s of milliseconds, are often interpreted as evidence of spike timing coordination between the two cells. However, there are other ways to covary which can generate very similar peaks. I
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24

Sherman, S. Murray, and Christof Koch. "The Anatomy and Physiology of Gating Retinal Signals in the Mammalian Lateral Geniculate Nucleus." 1985. http://hdl.handle.net/1721.1/5624.

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In the mammalian visual system, the lateral geniculate nucleus is commonly thought to act merely as a relay for the transmission of visual information from the retina to the visual cortex, a relay without significant elaboration in receptive field properties or signal strength. However, many morphological and electrophysiological observations are at odds with this view. In this paper, we will review the different anatomical pathways and biophysical mechanisms possibly implementing a selective gating of visual information flow from the retina to the visual cortex. We will argue tha
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