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Journal articles on the topic 'Laugh and risk. eng'

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Published: 4 June 2021
Last updated: 15 February 2022

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1

Грабарчук, О. Н., and Н. В. Рибачук. "ЮМОР В ПРОСТРАНСТВЕ СОВРЕМЕННОЙ УКРАИНСКОЙ КУЛЬТУРЫ." Humanities journal, no. 2 (October 29, 2018): 72–79. http://dx.doi.org/10.32620/gch.2018.2.08.

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An integral part of any person’s life is humor. It makes our life more attractive, it hides a huge potential of vitality, wherein humor is a risk zone, where it can be presented as something devastating and derogative.The last 4 years of the most difficult social and political processes of Ukrainian reality we can observe a splash of interest to humorous programs of various kinds. Several separate channels began its functioning by offering to view only comical and funny content. This phenomenon makes one to think about humor specifics, about necessity of interaction with the comic, about its importance not only for one person but for the whole country. Thus, the aim of the research is to determine the place of the humor in the contemporary Ukrainian culture.The humor subject is well represented in the history of the humanitarian sciences, however, due to the ambiguity of the subject of the study, this topic remains open for further researches. There are three main theories of humor, such as consolation theory, superiority theory and discrepancy theory. And each theory finds its own proponent.The main statement of the consolation theory is that humor is a way to cope with inner tension and the opportunity to get a pleasure from laughing. In the superiority theory the sense of satisfaction from the excellence while observing a fun person as a week, stupid, unsuccessful takes the first place. In the discrepancy theory the contrast between expected and real is important for understanding the humor nature, detecting the discrepancies of our ideas about things (concepts, categories) to its real embodiments, that in the end bring out the laugh. The success of the joke is the success of finding the hidden absurdity in it.Ukrainian science also provides some developments in this sphere. Annual scientific and theoretical conference devoted to the humor theme takes place in Odessa I. I. Mechnikov National University. The question of comical in human being and its cognition as well as forms of comical in literature and art are raised.To our mind, tragic social processes, which were taking place in Ukraine over the last 4 years, with no doubt lead to a rapid increase of society tension. In such conditions laugh is a good way to cope with negative consequences, as pointed in the consolation theory, humor and laugh are the opportunity to protect themselves painlessly, specifically Ukrainian society, from mental overload. As Freud pointed out, humor, irony and comic offer us a quick way not only to relieve tension, but also to get a pleasure, to live through the moment being happy. The moment of happiness and pleasure, the experience of consolation are the factors that determine the comical in the rank of priorities when choosing a particular discourse in conditions of the complex tragic situation.As any psychological protection the comical has two sides. To a certain moment, laugh is a relief from pain, as a result it becomes the cause of psychological anesthesia, the inability to fully experience the feelings and emotions that correspond to the situation context.However, this particularity of contemporary individual is connected not so with humor as with its overabundance. Also it is connected with overabundance of the information which is consumed in conditions of the informative society and society of consuming.On the other hand, humor supports Ukrainian society by contributing the stabilization of the social processes. Apparently, ironic discourse, which captured TV screens and Ukrainian YouTube, is the rescue for the Ukrainians and it proves one more time the ideas about consolation theory of humor.
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2

Jang, I. Jin, and Carlos Cordero-Pedrosa. "To Laugh or Not to Laugh at Racist Jokes." Peace Review 28, no. 4 (October 2016): 474–81. http://dx.doi.org/10.1080/10402659.2016.1237116.

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3

Stengers, Isabelle. "Another Look: Relearning to Laugh." Hypatia 15, no. 4 (2000): 41–54. http://dx.doi.org/10.1111/j.1527-2001.2000.tb00348.x.

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It may be that denouncing the ideals of objectivity or neutrality associated with the sciences leads us into a trap: that of accepting, in order to criticize it, that there would be a common identity for the many ways to produce science. Learning to laugh, we choose to laugh with and laugh at. But we accept the risk of being interested, that is, of giving up the position of a judge.
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4

Rhodes, Nancy, and Morgan E. Ellithorpe. "Laughing at Risk: Sitcom Laugh Tracks Communicate Norms for Behavior." Media Psychology 19, no. 3 (January 12, 2016): 359–80. http://dx.doi.org/10.1080/15213269.2015.1090908.

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5

Wright, Travis. "Learning to Laugh: A Portrait of Risk and Resilience in Early Childhood." Harvard Educational Review 80, no. 4 (December 1, 2010): 444–64. http://dx.doi.org/10.17763/haer.80.4.w18726475585x5t2.

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In this portrait, Travis Wright documents young Goddess's capacity for strength in the face of trauma and neglect. Goddess, a sixteen-month-old child who has never laughed, is Wright's first client at his clinical internship during his graduate studies. Drawing on his work with Goddess, her mother, and her teachers, Wright explores the ways in which these many relationships help Goddess learn to laugh. Goddess's story provides a vivid depiction of the consequences of negative experiences in early childhood and the potential for programs to help children move beyond traumatic beginnings. The author describes how, through Goddess, he learns to see strength in behaviors he previously thought to be maladaptive. In reflecting on Goddess's agency in her transformation as well as on his own, Wright beautifully documents one child's journey from risk to resilience.
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6

Lee, Li‐Hsiang. "What is it about “bitch” that makes us laugh?" Peace Review 10, no. 4 (December 1998): 549–51. http://dx.doi.org/10.1080/10402659808426202.

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7

Kowalski, Jan, and Mieczyslaw Polonski. "Identification of risk investment using the risk matrix on railway facilities." Open Engineering 8, no. 1 (December 17, 2018): 506–12. http://dx.doi.org/10.1515/eng-2018-0057.

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Abstract The implementation of construction projects is fraught with many hazards that are difficult to determine at the stage of the tender procedure. Usually, the identification of these hazards rests with the contractors. In many cases this diagnosis is not used due to the lack of access to reliable data and easy-to-use computer programs supporting the risk analysis process. In order to facilitate the analysis and risk assessment on Polish railway investments, the authors present a proposal for the assessment of potential hazards that may occur during the implementation of these investments with the use of their point assessment. The proposed method is an original attempt to apply a point assessment of risk factors, whose final result is ready investment risk assessment matrices at the design and execution stage of constructionworks. The basis for the development of matrices was questionnaire surveys involving a large group of experts with extensive professional experience. In addition, the project manager can set the partial weights of hazards separately for time and cost hazards depending on the assessment of the planned project. In order to quickly calculate the weights of individual risk factors for any defined time and cost of partial weights, the authors developed the proposed matrices in the form of a calculation sheet. The matrices can be used to assess potential hazards to future infrastructure investments.
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8

Fine, Gary Alan. "Dying for a Laugh: Negotiating Risk and Creating Personas in the Humor of Mushroom Collectors." Western Folklore 47, no. 3 (July 1988): 177. http://dx.doi.org/10.2307/1499916.

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9

Al-Shayea, Adel, Khalid Al-Saleh, Khalid Al-Yami, and Abdulaziz El-Tamimi. "Productivity Improvement Model without Increasing Operation’s Risk and Fatigue." Engineering 03, no. 11 (2011): 1124–31. http://dx.doi.org/10.4236/eng.2011.311140.

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10

Strohmandl, Jan, and Zdeněk Čujan. "Risk Minimisation in Integrated Supply Chains." Open Engineering 9, no. 1 (December 10, 2019): 593–99. http://dx.doi.org/10.1515/eng-2019-0082.

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AbstractIntegrated supply chains, due to their complexity, are vulnerable in relation to various types of risks, especially in the present turbulent market environment, characterised by increased demand for effectiveness of the individual logistic activities, extended customer service and decreased cost. The supply chain risks are represented by any threatening event that may unexpectedly disrupt or restrict material flow, or directly stop the scheduled logistic or manufacturing activities. Supply chain risk management includes risk identification, analysis and implementation of measures against potential risk consequences. This article describes supply chain management, risk elimination methods in the case of a technological breakdown and potential subsequent supply chain failure and application of the modified Failure Mode, Effects & Criticality Analysis (FMECA).
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11

Paredes, Simao, Teresa Rocha, Paulo de Carvalho, Jorge Henriques, Ramona Cabiddu, and João Morais. "Heart Rate Variability Applied to Short-Term Cardiovascular Event Risk Assessment." Engineering 05, no. 10 (2013): 237–43. http://dx.doi.org/10.4236/eng.2013.510b049.

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12

Zhang, Meihua, Yuan Yao, and Kefan Xie. "Prediction and Diversion Mechanisms for Crowd Management Based on Risk Rating." Engineering 09, no. 05 (2017): 377–87. http://dx.doi.org/10.4236/eng.2017.95021.

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13

Rong, Quanbing, Hongjun Zhang, and Fengshan Wang. "Entropy-Based Set Pair Analysis Model on Geological Disaster Risk for Military Engineering." Engineering 04, no. 02 (2012): 76–82. http://dx.doi.org/10.4236/eng.2012.42010.

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14

Baby, Sultana Nasrin, Colin Arrowsmith, Gang-Jun Liu, David Mitchell, Nadhir Al-Ansari, and Nahala Abbas. "Developing a Spatial Tool for Assessing Coastal Community and Identifying Infrastructure at Risk." Engineering 13, no. 01 (2021): 45–55. http://dx.doi.org/10.4236/eng.2021.131004.

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15

Fenech, Marianne, Jennifer Sumsion, and Joy Goodfellow. "Regulation and risk: early childhood education and care services as sites where the ‘laugh of Foucault’ resounds." Journal of Education Policy 23, no. 1 (January 2008): 35–48. http://dx.doi.org/10.1080/02680930701754039.

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16

Volkova, A. T., O. S. Tselousova, and I. A. Potapova. "Cytogenetic monitoring of environmental health risk in Bashkortostan." Health Risk Analysis 3 (March 2014): 56–60. http://dx.doi.org/10.21668/health.risk/2014.3.07.eng.

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17

Bragin, E. V. "Risk factors which cause senile cataract evolvement: outline." Health Risk Analysis, no. 1 (2018): 113–25. http://dx.doi.org/10.21668/health.risk/2018.1.13.eng.

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18

Osaulenko, L. N. "VULNERABILITY AS A SPECIFIC CATEGORY OF CONSUMER RISK." Health Risk Analysis, no. 3 (September 2018): 24–30. http://dx.doi.org/10.21668/health.risk/2018.3.03.eng.

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19

Borodulina, E. A., and E. V. Yakovleva. "Contemporary risk factors that cause disseminated lung diseases." Health Risk Analysis, no. 4 (December 2020): 181–87. http://dx.doi.org/10.21668/health.risk/2020.4.20.eng.

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As per data provided by Rosstat, in 2018 primary morbidity with respiratory diseases amounted to 35,982 per 100 thousand people; respiratory diseases account for more than 25% in the structure of overall population morbidity and they to a great extent depend on risk factors occurrence. Disseminated lung diseases are combined into one specific group among respiratory diseases as per x-ray evidence. Our research goal was to review contemporary risk factors that cause disseminated lung diseases in order to apply them in diagnostics. We searched for scientific works that were relevant for our research in such databases as RSCI, CyberLeninka, Scopus, Web of Science, MedLine, and PubMed. There are a lot of classifications for disseminated lung diseases based on morphologic substrate peculiarities, etiology and other signs; it proves the issue is truly complicated. Patients with disseminated damage to lungs have similar x-ray picture of the disease and results obtained via general clinical tests also have no pathognomonic peculiarities. Clinical experts usually divide disseminations into those with infectious genesis (tuberculosis, HIV-associated disseminations, and fungus diseases) and those with non-infectious genesis (tumor disseminations, interstitial lung diseases, lysosomal storage disorders, etc.). The review outlines factors that influence both occurrence and development of lung diseases accompanied with dissemination syndrome. The greatest attention is paid to socially significant diseases as risk factors that cause them can be detected by a doctor in a patient’s case history and applied for differential diagnostics. It is necessary to develop relevant prevention activities aimed at reducing risks of disseminated lung diseases as they will allow preventing morbidity and mortality among patients suffering from lung disseminations caused by correctable risk factors.
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20

Hanak, Tomas, and Jana Korytarova. "Subsidy Risk Related to Construction Projects: Seeking Causes." Open Engineering 8, no. 1 (November 24, 2018): 484–89. http://dx.doi.org/10.1515/eng-2018-0060.

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AbstractMany construction projects are realized with public subsidy, e.g. subsidies from the European Union, state budget and/ or municipal resources. The reimbursement of the subsidy depends on a number of conditions, such as completion of the project in time or compliance with operation conditions. The purpose of this research is to seek causes of subsidy risk related to construction projects. In particular, research aims at addressing causes that may lead to the loss of subsidy, reduction of subsidy and/or a penalty payment. Research is conducted as a case study of selected construction projects and the Czech Republic is chosen as a study area. Set of data representing 20 construction projects which faced the threat of reduction or loss of subsidy was collected from available sources and results represent the spectrum of identified risk causes and their distribution in the different phases of the project life cycle and according to the risk source breakdown structure. From managerial perspective, output of this research may serve as a support for investors who plan to apply for public subsidy for their construction projects. Several recommendations for subsidy risk avoidance have been proposed at the end of the paper.
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21

Borodulina, E. A., and E. V. Yakovleva. "Contemporary risk factors that cause disseminated lung diseases." Health Risk Analysis, no. 4 (December 2020): 181–87. http://dx.doi.org/10.21668/health.risk/2020.4.20.eng.

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As per data provided by Rosstat, in 2018 primary morbidity with respiratory diseases amounted to 35,982 per 100 thousand people; respiratory diseases account for more than 25% in the structure of overall population morbidity and they to a great extent depend on risk factors occurrence. Disseminated lung diseases are combined into one specific group among respiratory diseases as per x-ray evidence. Our research goal was to review contemporary risk factors that cause disseminated lung diseases in order to apply them in diagnostics. We searched for scientific works that were relevant for our research in such databases as RSCI, CyberLeninka, Scopus, Web of Science, MedLine, and PubMed. There are a lot of classifications for disseminated lung diseases based on morphologic substrate peculiarities, etiology and other signs; it proves the issue is truly complicated. Patients with disseminated damage to lungs have similar x-ray picture of the disease and results obtained via general clinical tests also have no pathognomonic peculiarities. Clinical experts usually divide disseminations into those with infectious genesis (tuberculosis, HIV-associated disseminations, and fungus diseases) and those with non-infectious genesis (tumor disseminations, interstitial lung diseases, lysosomal storage disorders, etc.). The review outlines factors that influence both occurrence and development of lung diseases accompanied with dissemination syndrome. The greatest attention is paid to socially significant diseases as risk factors that cause them can be detected by a doctor in a patient’s case history and applied for differential diagnostics. It is necessary to develop relevant prevention activities aimed at reducing risks of disseminated lung diseases as they will allow preventing morbidity and mortality among patients suffering from lung disseminations caused by correctable risk factors.
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22

Vu, Hong Anh, Jianqiong Wang, Lianxing Min, Sy Hung Mai, and Hong Phong Nguyen. "Research on Cost Overrun Risk of Construction Phase of Vietnam Highway International Contracting Project." Engineering 08, no. 03 (2016): 86–98. http://dx.doi.org/10.4236/eng.2016.83011.

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23

Sabanov, S., J.-R. Pastarus, O. Nikitin, and E. Väli. "Risk assessment of seismic impact on the roof and pillars stability in Estonian underground." Estonian Journal of Engineering 57, no. 4 (2008): 325. http://dx.doi.org/10.3176/eng.2008.4.04.

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24

Gankin, A. N., T. D. Gritsenko, S. M. Sokolov, and T. N. Pronina. "Health risk of pupils formed by classrooms’ air pollution." Health Risk Analysis, no. 1 (January 2014): 40–48. http://dx.doi.org/10.21668/health.risk/2014.1.05.eng.

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25

Lebedeva-Nesevrya, N. A. "Risk-communications as an instrument for public health management." Health Risk Analysis, no. 2 (February 2014): 83–89. http://dx.doi.org/10.21668/health.risk/2014.2.10.eng.

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26

Bagryantseva, O. V., G. N. Shatrov, S. А. Khotimchenko, V. V. Bessonov, and О. V. Arnautov. "Aluminium: Food-related health risk assessment of the consumers." Health Risk Analysis, no. 1 (January 2016): 59–68. http://dx.doi.org/10.21668/health.risk/2016.1.07.eng.

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27

Bukhtiyarov, I. V., O. I. Yushkova, M. A. Fesenko, and A. G. Merkulova. "Fatigue risk assessment for workers with neuro-enmotional labor." Health Risk Analysis, no. 1 (2018): 66–77. http://dx.doi.org/10.21668/health.risk/2018.1.08.eng.

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28

Aringazina, A. M., O. Zh Narmanova, G. O. Nuskabaeva, Zh A. Tagaeva, and E. S. Mendybaev. "Chronic kidney disease: prevalence and risk factors (literature review)." Health Risk Analysis, no. 2 (June 2020): 164–74. http://dx.doi.org/10.21668/health.risk/2020.2.18.eng.

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29

Petrova, P. Yu, A. D. Aga, E. S. Trapeznikova, and E. V. Budanova. "Gut microbiota as risk factor causing obesity in children." Health Risk Analysis, no. 1 (March 2021): 159–72. http://dx.doi.org/10.21668/health.risk/2021.1.17.eng.

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Nowadays obesity resulting from abnormal or excessive fat deposits in a body has become a true epidemic. Risk factors that cause the disease include improper lifestyle, hereditary predisposition, as well as metabolic activity of gut microbiota. Research works performed over the last decades indicate that microbes that create colonies in human intestines play a significant role in maintaining proper metabolism. There is a correlation between disorders in gut microbiota structure and immune disorders, elevated susceptibility to infections, and obesity. There is more and more evidence that gut microbiota and its overall bacterial genome exert their influence on nutrients assimilation and regulate energy metabolism and fat accumulation. Certain differences were detected in microbiota gut structure in children and adults with obesity and people with proper body mass index. Delivery and feeding are among key factors influencing gut microbiota formation in a child. Thus, research results indicate that natural birth, as opposed to cesarean section, can prevent obesity occurrence in a child. Breast-feeding also makes a substantial contribution into development of an infant since breast milk is balanced food that provides optimal metabolism in an infant’s body and helps creating proper gut microbiota. At the same time, according to data obtained via numerous research works, artificial feeding can be related to obesity occurrence in future. Ways to fight obesity include medication therapy, dietary nutrition, physical activity as well as bariatric surgery; the latter is nowadays considered to be the most efficient procedure on the matter. Reduction in body mass via influencing gut microbiota is a promising trend in research in the sphere. Despite there are objective data on benign effects produced by probiotics and prebiotics on gut microbiota, experts haven’t been able to reach agreement on their efficiency yet.
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30

Boev, V. M., M. V. Boev, L. M. Tulina, and A. A. Neplokhov. "Determined ecological human health risk factors in single factory towns." Health Risk Analysis, no. 2 (February 2013): 39–44. http://dx.doi.org/10.21668/health.risk/2013.2.04.eng.

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31

Buzinov, R. V., and T. N. Unguryanu. "An assessment of the risk associated with behavioral lifestyle factors." Health Risk Analysis, no. 2 (February 2013): 45–48. http://dx.doi.org/10.21668/health.risk/2013.2.05.eng.

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32

Unguryanu, T. N. "Subjective evaluation and perception of risk by various population groups." Health Risk Analysis, no. 3 (March 2013): 82–87. http://dx.doi.org/10.21668/health.risk/2013.3.10.eng.

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33

Mukhammadieva, G. F., L. K. Karimova, A. B. Bakirov, V. A. Kaptsov, N. A. Beygul, Z. F. Gimaeva, and L. N. Mavrina. "Prevention of cancer risk of workers of glass fibers manufacture." Health Risk Analysis, no. 3 (March 2016): 80–87. http://dx.doi.org/10.21668/health.risk/2016.3.09.eng.

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34

Volgareva, A. D., L. K. Karimova, L. N. Mavrina, Z. F. Gimaeva, and N. A. Beigul. "In-plant noise as occupational risk factor at petrochemical plants." Health Risk Analysis, no. 1 (January 2017): 116–24. http://dx.doi.org/10.21668/health.risk/2017.1.13.eng.

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35

Badamshina, G. G., V. B. Ziatdinov, G. Sh Isaeva, M. A. Kirillova, and S. S. Zemskova. "Analysis of risk for infections related to providing medical assistance." Health Risk Analysis, no. 2 (February 2017): 113–18. http://dx.doi.org/10.21668/health.risk/2017.2.12.eng.

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36

Zhdanova-Zaplesvichko, I. G. "Irrational nutrition as populattion health risk factor in Irkutsk region." Health Risk Analysis, no. 2 (June 2018): 23–32. http://dx.doi.org/10.21668/health.risk/2018.2.03.eng.

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37

Deryabin, A. N., T. N. Unguryanu, and R. V. Buzinov. "Population health risk caused by exposure to chemicals in soils." Health Risk Analysis, no. 3 (September 2019): 18–25. http://dx.doi.org/10.21668/health.risk/2019.3.02.eng.

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38

Abreu, António, José Moleiro Martins, and João M. F. Calado. "A fuzzy reasoning approach to assess innovation risk in ecosystems." Open Engineering 8, no. 1 (December 26, 2018): 551–61. http://dx.doi.org/10.1515/eng-2018-0067.

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Abstract Currently, companies to be competitive must achieve high rates of innovation and respond quickly to market needs. According to a number of managers and researches innovation is crucial for companies to stay “alive." Taking into account several reports, the development of co-innovation networks based on a collaborative environment is the best strategy to support innovation projects. However, the absence of mechanisms to detect and even anticipate potential risks of innovation based on a collaborative approach is an obstacle to the proliferation of this way of working. To address this issue, this paper discusses an approach based on fuzzy reasoning for analyzing the level of risk in co-innovation projects. It is discussed how this approach can be applied to co-innovation projects within the context of a collaborative ecosystem. At last, it is discussed the benefits, and challenges found on experimental results from a Portuguese co-innovation network.
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39

Bakirov, A. B., S. R. Mingazova, L. K. Karimova, P. V. Serebryakov, and G. F. Mukhammadieva. "Risk of dust bronchopulmonary pathology development in workers employed in various economic brunches under impacts exerted by occupational risk factors: clinical and hygienic aspects." Health Risk Analysis, no. 3 (March 2017): 83–91. http://dx.doi.org/10.21668/health.risk/2017.3.10.eng.

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40

Svebak, Sven. "Consequences of laughter upon trunk compression and cortical activation: Linear and polynomial relations." Europe’s Journal of Psychology 12, no. 3 (August 19, 2016): 456–72. http://dx.doi.org/10.5964/ejop.v12i3.1102.

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Results from two studies of biological consequences of laughter are reported. A proposed inhibitory brain mechanism was tested in Study 1. It aims to protect against trunk compression that can cause health hazards during vigorous laughter. Compression may be maximal during moderate durations and, for protective reasons, moderate in enduring vigorous laughs. Twenty-five university students volunteered to see a candid camera film. Laughter responses (LR) and the superimposed ha-responses were operationally assessed by mercury-filled strain gauges strapped around the trunk. On average, the thorax compression amplitudes exceeded those of the abdomen, and greater amplitudes were seen in the males than in the females after correction for resting trunk circumference. Regression analyses supported polynomial relations because medium LR durations were associated with particularly high thorax amplitudes. In Study 2, power changes were computed in the beta and alpha EEG frequency bands of the parietal cortex from before to after exposure to the comedy “Dinner for one” in 56 university students. Highly significant linear relations were calculated between the number of laughs and post-exposure cortical activation (increase of beta, decrease of alpha) due to high activation after frequent laughter. The results from Study 1 supported the hypothesis of a protective brain mechanism that is activated during long LRs to reduce the risk of harm to vital organs in the trunk cavity. The results in Study 2 supported a linear cortical activation and, thus, provided evidence for a biological correlate to the subjective experience of mental refreshment after laughter.
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41

Kukushkin, Yu, A. Vorona, A. Bogomolov, and S. Chistov. "Risk measurament of the staff occupied in chemical weapons destruction facilities." Health Risk Analysis 3 (March 2014): 26–33. http://dx.doi.org/10.21668/health.risk/2014.3.03.eng.

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42

Dubel, E. V., and T. N. Unguryanu. "Assessment of behavioral risk factors of medical workers at multidisciplinary hospital." Health Risk Analysis, no. 2 (February 2016): 60–67. http://dx.doi.org/10.21668/health.risk/2016.2.07.eng.

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43

Davletova, N. Ch, I. A. Zemlenukhin, D. S. Martykanova, S. M. Mugallimov, and A. M. Akhatov. "Hygienic assessment of risk factors for skin infections in athletes–wrestlers." Health Risk Analysis, no. 3 (March 2016): 53–60. http://dx.doi.org/10.21668/health.risk/2016.3.06.eng.

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44

Suchkov, V. V., S. A. Khotimchenko, O. V. Sazonova, D. O. Gorbachev, T. K. Ryazanova, and E. A. Semaeva. "Population health risk related to increased content of benzpyrene in soil." Health Risk Analysis, no. 2 (February 2017): 65–72. http://dx.doi.org/10.21668/health.risk/2017.2.07.eng.

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45

Migacheva, A. G., T. A. Novikova, V. F. Spirin, and D. M. Shlyapnikov. "A priori assessment of occupational health risk for vegetables greenhouse workers." Health Risk Analysis, no. 3 (March 2017): 101–8. http://dx.doi.org/10.21668/health.risk/2017.3.12.eng.

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46

Popova, A. Yu. "Risk analysis as a strategic sphere in providing food products safety." Health Risk Analysis, no. 4 (December 2018): 4–12. http://dx.doi.org/10.21668/health.risk/2018.4.01.eng.

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47

Rakitskii, V. N. "Contemporary challenges and ways to improve health risk assessment and management." Health Risk Analysis, no. 3 (September 2020): 23–29. http://dx.doi.org/10.21668/health.risk/2020.3.03.eng.

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We analyzed basic trends in improving risk assessment and management in Russia taking into account international experience; these trends arise from needs occurring in contemporary hygienic science and necessity to provide stronger resistance against new threats to population health. We substantiated specific tasks in development of health risk analysis mythology basing on preconditions for finding solutions to them in Russia; we also determined practical issues in its implementation that are the most vital and need solutions in the nearest future in order to eliminate adverse impacts on the environment and population health. The primary results are creation of a long-term strategy for the development of health risk analysis principles that takes into account the latest scientific data and is aimed at solving the following methodological and practical tasks: implementation of a systemic approach in estimating carcinogenic / non-carcinogenic risks; development of a unified approach to accomplishing toxicological «dose – response» examinations and interpreting their results which will take into account background morbidity and background dose burdens and determine susceptible population groups and behavioral models; threshold levels obtained via determining «benchmark» concentrations taking spontaneous background into account in order to determine new RfD and RfC and revise existing ones; use of micronvironmental approach in exposure estimation; use of risk assessment methodology in BAT parameters implementation for providing control over health safety after new approaches aimed at reducing emissions have been implemented in environmental protection. The necessity to improve approaches to health risk assessment and management and tasks solved within the process have been taken into account when the Branch scientific research program for 2021–2025 was developed by Rospotrebnadzor.
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48

Ivanov, A. M., A. Zh Gil'manov, N. N. Malyutina, Ya B. Khovaeva, O. Yu Nenasheva, G. I. El'kin, and D. Yu Sosnin. "Polymorphism of folate cycle genes as a risk factor of hyperhomocysteinemia." Health Risk Analysis, no. 4 (December 2020): 137–46. http://dx.doi.org/10.21668/health.risk/2020.4.16.eng.

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Hyperhomocysteinemia (HHc) is a new factor being considered at the moment that can cause damage to vessel walls. Its occurrence depends on genetic peculiarities of a body. Our research goal was to estimate frequency of genetic polymorphisms (SNP) in folate cycle genes among people living in Perm region and its influence on homocysteine (Hc) concentration in blood serum. We examined 189 women (32.2±5.25). Hc concentration in blood serum was determined with immune chemiluminescent procedure. We examined frequency of SNP in folate cycle genes with pyrosequencing. Homozygote state as per minor alleles in methylene tetrahydrofolate reductase (MTHFR) gene (rs 1801133 и rs 1801131) and MTR gene (rs 1805087) was registered 7.5, 5.4, and 13.75 times less frequently than homozygote state as per neutral alleles. Heterozygote state prevailed for genes of methionine synthase reductase and folate transport protein among examined SNP. Homozygotes as per minor allele SNP in MTHFR gene (Ala222Val; rs 1801133) had higher Hc concentration in blood serum that amounted to 8.476 ± 3.193 mmol/L and was 1.276 times higher than the same parameter in homozygotes as per neutral allele (р=0.0036). We didn’t establish any influence on Hc contents in blood serum for the remaining 4 SNP in folate cycle genes (р> 0.1). Examined SNP in MTHFR and MTR genes tended to have neutral alleles more frequently than minor ones. SNP in genes of other examined proteins belonging to folate cycle didn’t have any differences in frequency of examined alleles. We didn’t detect a combination of homozygote state as per two SNP in MTHFR gene or homozygote state as per one SNP and heterozygote state as per another one in a genome. Only SNP in MTHFR gene (Ala222Val, rs 1801133) authentically causes increase in homocysteine concentration out of all the examined SNP in genes of folate cycle enzymes and proteins
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49

Ivanov, A. M., A. Zh Gil'manov, N. N. Malyutina, Ya B. Khovaeva, O. Yu Nenasheva, G. I. El'kin, and D. Yu Sosnin. "Polymorphism of folate cycle genes as a risk factor of hyperhomocysteinemia." Health Risk Analysis, no. 4 (December 2020): 137–46. http://dx.doi.org/10.21668/health.risk/2020.4.16.eng.

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Abstract:
Hyperhomocysteinemia (HHc) is a new factor being considered at the moment that can cause damage to vessel walls. Its occurrence depends on genetic peculiarities of a body. Our research goal was to estimate frequency of genetic polymorphisms (SNP) in folate cycle genes among people living in Perm region and its influence on homocysteine (Hc) concentration in blood serum. We examined 189 women (32.2±5.25). Hc concentration in blood serum was determined with immune chemiluminescent procedure. We examined frequency of SNP in folate cycle genes with pyrosequencing. Homozygote state as per minor alleles in methylene tetrahydrofolate reductase (MTHFR) gene (rs 1801133 и rs 1801131) and MTR gene (rs 1805087) was registered 7.5, 5.4, and 13.75 times less frequently than homozygote state as per neutral alleles. Heterozygote state prevailed for genes of methionine synthase reductase and folate transport protein among examined SNP. Homozygotes as per minor allele SNP in MTHFR gene (Ala222Val; rs 1801133) had higher Hc concentration in blood serum that amounted to 8.476 ± 3.193 mmol/L and was 1.276 times higher than the same parameter in homozygotes as per neutral allele (р=0.0036). We didn’t establish any influence on Hc contents in blood serum for the remaining 4 SNP in folate cycle genes (р> 0.1). Examined SNP in MTHFR and MTR genes tended to have neutral alleles more frequently than minor ones. SNP in genes of other examined proteins belonging to folate cycle didn’t have any differences in frequency of examined alleles. We didn’t detect a combination of homozygote state as per two SNP in MTHFR gene or homozygote state as per one SNP and heterozygote state as per another one in a genome. Only SNP in MTHFR gene (Ala222Val, rs 1801133) authentically causes increase in homocysteine concentration out of all the examined SNP in genes of folate cycle enzymes and proteins
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50

Masnavieva, L. B., N. V. Efimova, and I. V. Kudaeva. "Risk of sensitization to ecopollutants in teenagers with inherited chemical burden." Health Risk Analysis, no. 2 (June 2021): 123–31. http://dx.doi.org/10.21668/health.risk/2021.2.12.eng.

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At present allergic diseases are detected in 30% people and their frequency is only growing. A significant role in allergic pathology occurrence belongs to ambient air contamination and chemicals being introduced not only into children’s bodies, but their parents’ ones as well since pollutants can act as allergens and sensitizing agents. Our research goal was to examine influence exerted by parents’ pre-gestation exposure to chemicals on sensitization among teenagers living in an area where ambient air was contaminated. We examined overall immunoglobulin E contents and leukocytes migration inhibition test with formaldehyde and sodium nitrite in 115 teenagers whose parents worked under adverse working conditions at chemical and petrochemical enterprises and in 244 schoolchildren whose parents didn’t have any occupational contacts with chemicals. Each group was divided into sub-groups depending on inhalation chemical burden on schoolchildren’s bodies caused by ambient air contamination and contaminated air indoors (with hazard index (HI) for immune disorders being lower than 2 and HI≥2). The research allowed establishing that teenagers whose parents had worked at chemical and petrochemical enterprises during a pre-gestation period had elevated IgE contents more frequently as well as changes in leukocytes migration inhibition test with formaldehyde; it indicated there was sensitization to this chemical. Parents’ occupational contacts with chemicals led to an increase in relative risks of elevated igE contents and 2.5 times higher sensitization among schoolchildren with HI<2. Risk that sensitization to formaldehyde might occur was equal to 2.3 among senior schoolchildren with HI≥2 whose parents worked at chemical enterprises.
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