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1

Grimmer, Sten. "Steifigkeitsanpassung beim Laufen auf unebenem Terrain." Hamburg Kovač, 2007. http://d-nb.info/986460265/04.

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2

Petránková, Tereza. "Marketing analysis of brand Yves Saint Laurent in portfolio L´Oréal." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-136235.

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The aim of this thesis Marketing analysis of brand Yves Saint Laurent in portfolio L'Oréal is analysis of brand Yves Saint Laurent. The theoretical part focuses mainly on marketing, brand, luxury, analysis of brand and marketing strategies. Practical part based on the findings in theoretical part analysed brand - history, indentity, value and marketing strategy and reccomend new marketing strategies.
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3

Rudloff, Laurent. "Etudes expérimentales de paliers aérostatiques hybrides et des paliers aérodynamiques à feuilles." Poitiers, 2011. http://theses.univ-poitiers.fr/22002/2011-Rudloff-Laurent-These.pdf.

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Le travail présenté dans cette thèse est effectué sur deux bancs d'essais différents. Avec le premier banc d'essais, les caractéristiques dynamiques d'un palier aérostatique à air sont étudiées expérimentalement pour une configuration en rotor rigide. Le rotor est entraîné en rotation à 60 krpm par une turbine Pelton et monté horizontalement sur deux paliers aérostatiques identiques alimentés en air jusqu'à des pressions de 11 bar. La charge dynamique est appliquée soit par l'impact d'un marteau, soit par un balourd additionnel. Le banc d'essais permet la mesure de la pression et du débit d'alimentation des paliers, de la vitesse de rotation, la force d'impact, des déplacements dans les deux paliers, et de l'accélération des paliers. Ces données expérimentales et les équations du PFD appliquées au rotor permettent l'identification des coefficients dynamiques des paliers. Une validation de ces coefficients dynamiques expérimentaux est réalisée grâce à la réponse au balourd. La seconde partie, sur le second banc d'essais, présente les résultats d'une étude expérimentale des caractéristiques statiques et dynamiques d'un palier à feuilles de génération 1. Le banc d'essais est de type palier flottant, et peut atteindre des vitesses de 40 krpm. Deux modules différents sont utilisés pour mesurer les grandeurs de démarrage et les coefficients dynamiques. Avec le premier module, le banc d'essais peut mesurer les couples de démarrage. Dans sa seconde configuration, un module différent permet l'identification des coefficients dynamiques du palier à feuilles. Les coefficients de raideur et d'amortissement sont identifiés à partir des impédances complexes et permettent le calcul des fréquences propres. Les résultats expérimentaux montrent que les caractéristiques du palier testé ont une faible dépendance à la vitesse de rotation, mais varient avec la fréquence d'excitation
The thesis activities are made on two different test rigs. On the first test rig, the dynamic characteristics of a hybrid aerostatic bearing are experimentally investigated in a rigid rotor configuration. The rotor is driven up to 60 krpm by an impulse turbine and is horizontally mounted on two identical aerostatic bearings fed with are pressures up to 11 bar. Dynamic loads consist either of impacts provided by a hammer or of added unbalance masses. The test rig can measure the bearing feeding pressures and flow, the rotation speed, the impact force, the displacements of the two bearings and the bearing housing accelerations. This experimental information together with the equations of motion of the rotor enables the identification of the dynamic coefficients of the bearings. A validation of these coefficients is providing by the unbalanced response of the rotor. The second part, on the second test rig, presents the results of the experimental analysis of static and dynamic characteristics of a generation 1 foil bearing. The test rig is of floating bearing type, and can reach the speed of 40 krpm. Two different casings are used for start up and for measurement of dynamic coefficients. In its first configuration, the test rig is designed to measure the start up torque. In its second configuration, a different casing is used to measure the impedances of the foil bearing. Stiffness and damping coefficients are identified from the complex impedances and enable the calculation of natural frequencies. The experimental results show that the dynamic characteristics of the tested bearing have a weak dependence on the rotation speed but vary with the excitation frequency
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4

Rullgård, Hans. "Topics in geometry, analysis and inverse problems." Doctoral thesis, Stockholm University, Department of Mathematics, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-15.

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The thesis consists of three independent parts.

Part I: Polynomial amoebas

We study the amoeba of a polynomial, as de ned by Gelfand, Kapranov and Zelevinsky. A central role in the treatment is played by a certain convex function which is linear in each complement component of the amoeba, which we call the Ronkin function. This function is used in two di erent ways. First, we use it to construct a polyhedral complex, which we call a spine, approximating the amoeba. Second, the Monge-Ampere measure of the Ronkin function has interesting properties which we explore. This measure can be used to derive an upper bound on the area of an amoeba in two dimensions. We also obtain results on the number of complement components of an amoeba, and consider possible extensions of the theory to varieties of codimension higher than 1.

Part II: Differential equations in the complex plane

We consider polynomials in one complex variable arising as eigenfunctions of certain differential operators, and obtain results on the distribution of their zeros. We show that in the limit when the degree of the polynomial approaches innity, its zeros are distributed according to a certain probability measure. This measure has its support on the union of nitely many curve segments, and can be characterized by a simple condition on its Cauchy transform.

Part III: Radon transforms and tomography

This part is concerned with different weighted Radon transforms in two dimensions, in particular the problem of inverting such transforms. We obtain stability results of this inverse problem for rather general classes of weights, including weights of attenuation type with data acquisition limited to a 180 degrees range of angles. We also derive an inversion formula for the exponential Radon transform, with the same restriction on the angle.

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5

Stahn, Thorsten [Verfasser], Laurent [Akademischer Betreuer] Gizon, and Stefan [Akademischer Betreuer] Dreizler. "Analysis of time series of solar-like oscillations - Applications to the Sun and HD52265 / Thorsten Stahn. Gutachter: Stefan Dreizler ; Laurent Gizon. Betreuer: Laurent Gizon." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2011. http://d-nb.info/1043665625/34.

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6

Jones, Stephanie M. "Constructing marriage : a thematic analysis of self-help books on marriage /." [Boise, Idaho] : Boise State University, 2009. http://scholarworks.boisestate.edu/td/73/.

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7

Socié, Anne-Sarah. "Le développement durable face aux aspirations : analyses d’écologie sociale." Thesis, Paris 10, 2014. http://www.theses.fr/2014PA100100/document.

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Alors que le développement durable fait l’objet d’un corpus abondant de diagnostics et préconisations, ses promoteurs soutiennent également une certaine définition de la gouvernance recommandant la prise en compte des projections des habitants et usagers du territoire. Le développement durable est dès lors présenté à la fois comme une volonté de prospective participative (perspectives ouvertes) et comme une vision structurée du futur (perspectives programmées). Nous analysons ce paradoxe dans l'articulation entre aspirations et finalité. De 2009 à 2013, nous avons réalisé une observation participante au sein d’un projet visant l’élaboration participative de critères territorialisés de qualité de vie, conduit sur deux communes menant des politiques d’urbanisme se réclamant du développement durable. La thèse analyse l’existence de dynamiques complexes au niveau micro-territorial, entre la promotion du développement durable comme finalité et les aspirations exprimées : elles sont analysées en termes de leviers d’adhésion et de rejet, mais également de rôle et de paradoxes. Au cœur de ces dynamiques se jouent des processus de transformation sociale, portés par les promoteurs du développement durable comme finalité. La thèse soutient que cette transformation sociale s’appuie sur l’existence chez les acteurs d’aspirations paradoxales ; mais également sur la force du métarécit dans lequel s’inscrit le développement durable qui, créant un discours sur la résilience, se propose comme une voie de dépassement de ces apparentes contradictions
While sustainable development is an object of an abounding corpus of diagnoses and recommendations, its promoters also support a definition of governance recommending the consideration of inhabitants’ and users’ projections. Sustainable development is simultaneously presented as a will of participative prospective (opened perspectives) and as a structured vision of the future (scheduled perspectives). We analyze this paradox in the articulation between aspirations and purpose. From 2009 till 2013, we realized a participating observation within a project aiming the participative elaboration of territorialized criteria for quality of life. It was tested on two municipalities, leading town planning referring to sustainable development. This thesis analyzes the existence of complex micro-territorial dynamics, between promotion of sustainable development as a purpose and expressed aspirations. They are analyzed in terms of levels of involvement and rejection, but also role and paradoxes. At the heart of these dynamics happens processes of social transformation, such as leaded by promoters of sustainable development as a purpose. This thesis supports that this social transformation leans on the existence of paradoxical aspiration; but also on the strength of the metanarrative of sustainable development, creating a speech on resilience, proposes a way of overtaking these visible contradictions
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8

Zhang, Fengguo. "Determination of the stress field in polycrystalline materials by Laue microdiffraction." Thesis, Paris, ENSAM, 2015. http://www.theses.fr/2015ENAM0020/document.

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La microdiffraction Laue permet l'estimation des déformations élastiques à l'échelle du micron. La procédure d'analyse standard, bien établie, utilisée pour extraire les déformations élastiques des images de Laue est limitée par deux sources d'erreurs : la détermination de la positions des taches de Laue sur le détecteur, et la sensibilité aux paramètres de calibration du montage. Pour améliorer la procédure, nous avons développé une procédure appelée Laue-DIC qui utilise la très bonne résolution de la technique de corrélation d'images numériques (DIC). Cette méthode utilise, pour la détermination de l'incrément de déformation élastique et de rotation, le déplacement des pics entre deux configurations mécaniques, estimé par DIC, au lieu de leur position. Nous montrons que cette méthode donne un profil de contrainte en meilleur accord avec les solutions analytiques et numériques, pour des échantillons monocristallins déformés en flexion 4-points. Nous proposons également une méthode Laue-DIC améliorée, dans laquelle les paramètres de calibration sont estimés à chaque point de mesure, simultanément à la déformation élastique.En parallèle à la formulation de la méthode Laue-DIC (améliorée), nos efforts ont porté sur l'estimation de l'incertitude obtenue sur les déformations élastiques. Nous avons développé un modèle de bruit pour les images de Laue mesurées en rayonnement synchrotron, qui a été validé sur des séries de données, et qui nous a permis d'estimer les erreurs statistiques de la DIC, à partir d'images de Laue synthétiques. Ces erreurs ont ensuite été propagées dans la méthode Laue-DIC afin d'estimer les incertitudes sur les déformations élastiques, que l'on trouve en bon accord avec la fluctuation des contraintes locales estimées
Laue microdiffraction is a powerful technique to characterize the intragranular elastic strain field at the scale of micrometer. Although a standard procedure extracting elastic strain and crystal orientation from Laue image has been well-established, it can suffer from two sources of uncertainties: the determination of peaks' positions and the sensitivity to calibration parameters. In light of the high accuracy of digital image correlation (DIC), we developed the so-called Laue-DIC method which used the peaks' displacements measured by DIC instead of peaks' positions to determine the elastic strain increment and rotation between two mechanical configurations. This method has been proved more efficient than the standard procedure in terms of stress profiles of bended beam. We also developed the enhanced version of Laue-DIC. By using the term “enhanced”, we mean that we attempt to obtain both lattice matrices and calibration parameters of two configurations rather than solely the elastic strain increment and rotation from peaks' displacements.Aside from the formulation of Laue-DIC, we also developed a procedure of statistically estimating the errors of elastic strain/stress resulted from DIC errors and calibration accuracy. We have first validated a classical noise model, Poissonian-Gaussian model, from diffraction images acquired at synchrotron radiation facility. With the noise model, we could statistically estimate the DIC errors by synthesizing artificial spots. The estimated DIC errors were further transmitted into the errors of Laue-DIC through statistical tests
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9

Massey, Karen A., Anna M. Snelling, and Anna Nicolaou. "Quantitative analysis of surfactant deposits on human skin by liquid chromatography electrospray ionisation tandem mass spectrometry." Wiley, 2010. http://hdl.handle.net/10454/4574.

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no
Surfactants are commonly used as cleansing agents and yet there are concerns they may also have a role in skin irritation. Presently, the lack of suitable methods for quantitative and qualitative analysis of surfactant deposition on skin has hindered the in-depth investigation of such effects. Here, we report the application of reverse phase liquid chromatography electrospray ionisation mass spectrometry (LC/ESI-MS/MS) assays for two surfactants commonly used in consumer products, namely sodium lauryl ether sulphate (SLES) and laurylamidopropyl betaine (LAPB), to a baseline study aiming to assess deposition levels on human skin. The linearity of the assays was established at 3-20 ng, with coefficient of variation below 5%. Detection limits were 100 pg for LAPB and 1 ng for SLES; quantitation limits were 500 pg for LAPB and 2.5 ng for SLES. The baseline study was conducted using a panel of 40 healthy volunteers. Skin extract samples were taken in triplicate from forearms, using ethanol. SLES was detected on most volunteers, with 75% of them having SLES deposits in the range of 100-600 ng/cm2. LAPB was detected on the skin of all volunteers with 85% of them having deposit levels within the concentration range of 1-100 ng/cm2. These results demonstrate the extent to which commonly used surfactants remain on the skin during the day. The analytical methods reported here can be applied to the investigation of surfactants in relation to general skin condition and the development and optimisation of new consumer wash products.
EPSRC
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10

Neher, Torsten [Verfasser], Laurenz [Akademischer Betreuer] Wiskott, and Denise [Akademischer Betreuer] Manahan-Vaughan. "Analysis of the formation of memory and place cells in the hippocampus / Torsten Neher. Gutachter: Laurenz Wiskott ; Denise Manahan-Vaughan." Bochum : Ruhr-Universität Bochum, 2016. http://d-nb.info/1095884689/34.

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11

Wilbert, Niko [Verfasser], Richard [Akademischer Betreuer] Kempter, Laurenz [Akademischer Betreuer] Wiskott, and Felix [Akademischer Betreuer] Wichmann. "Hierarchical Slow Feature Analysis on visual stimuli and top-down reconstruction / Niko Wilbert. Gutachter: Richard Kempter ; Laurenz Wiskott ; Felix Wichmann." Berlin : Humboldt Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://d-nb.info/102372572X/34.

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12

Freudenthal, Jantje [Verfasser], Stefan [Akademischer Betreuer] Dreizler, Stefan [Gutachter] Dreizler, and Laurent [Gutachter] Gizon. "Follow-up and dynamical analysis of Kepler targets with transit timing variations / Jantje Freudenthal ; Gutachter: Stefan Dreizler, Laurent Gizon ; Betreuer: Stefan Dreizler." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://d-nb.info/1211556867/34.

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13

Cline, Morgan Paige. "When the News is the News: A Textual Analysis of NBC and CBS networks' Response to Sexual Harassment Allegations in the Wake of the #MeToo Movement." Thesis, Virginia Tech, 2020. http://hdl.handle.net/10919/99204.

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As the #MeToo movement swept the nation from Hollywood to Washington, within less than a week's time in November of 2017, longstanding news anchors, Matt Lauer and Charlie Rose were fired from their respective news networks because of sexual harassment allegations. As a result, each network had to grapple with repairing a destroyed image while simultaneously fulfilling the duty to report on news objectively. This qualitative analysis examined NBC and CBS's response to the allegations of sexual harassment against each anchor, allegations of withholding information and allegations of ignoring complaints through the lens of image repair theory in order to identify if any of the strategies were present in the networks' response. Applications of image repair discourse to news media organizations is a relatively novel examination and it highlights the complex duality of an organization's right to uphold its image but obligation to present the news objectively, even when it has become the news.
Master of Arts
As the #MeToo movement swept the nation from Hollywood to Washington, within less than a week's time in November of 2017, longstanding news anchors, Matt Lauer and Charlie Rose were fired from their respective news networks because of sexual harassment allegations. As a result, each network had to grapple with repairing a destroyed image while simultaneously running business as usual. This study examined NBC and CBS's response to the allegations of sexual harassment against each anchor, the allegations of withholding information and allegations of ignoring complaints made by employees over the past two decades, all the while attempting to fulfill the duty of objectively reporting the news. This study examined each networks' response using a crisis communication theory and offers an extension to the theory that can be utilized by news network organizations and the like.
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Escalante, Bañuelos Alberto Nicolás [Verfasser], Laurenz [Gutachter] Wiskott, and Rolf [Gutachter] Würtz. "Extensions of hierarchical slow feature analysis for efficient classsification and regression on high-dimensional data / Alberto Nicolás Escalante Bañuelos ; Gutachter: Laurenz Wiskott, Rolf Würtz." Bochum : Ruhr-Universität Bochum, 2017. http://d-nb.info/1140223186/34.

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15

Bledsoe, Stormi Danielle. "Liberte Egalite Sororite: Feminist Directing Strategies Applied to The Revolutionists at Miami University." Miami University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1564606867621745.

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16

Rocha, Fabio Carlos da. "Formulação do MEC considerando efeitos microestruturais e continuidade geométrica G1: tratamento de singularidade e análise de convergência." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/18/18134/tde-20052015-085721/.

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Neste trabalho, uma abordagem micromecânica com aproximação da geometria dada por funções de Bézier triangulares com continuidade geométrica G1 é inserida ao Método dos Elementos de Contorno, o qual é aplicado em problemas da elastostática tridimensional. Para consideração do efeito microestrutural, foi utilizado a teoria gradiente elástica simplificada de Aifantis, a qual é uma particularização da teoria geral de Mindlin. Nesta teoria, um argumento variacional é estabelecido para determinar todas as possíveis condições de contorno, clássica e não-clássica, para o problema de valor de contorno geral. A partir deste argumento, a solução fundamental da elasticidade gradiente é explicitada e com o auxílio da identidade integral recíproca é construído a representação integral de contorno. Para tornar o problema de valor de contorno bem-posto, em adição à representação integral de contorno para deslocamento, uma segunda representação integral para derivada normal do deslocamento foi utilizada. Expressões integrais para deslocamento e tensão em pontos internos são apresentadas. Todos os núcleos das equações integrais são explicitamente desenvolvidos. Para a discretização do MEC foram utilizados elementos triangulares curvos, aproximados tanto para a geometria quanto para os parâmetros físicos por funções de Proriol (com características espectrais) e por funções aqui chamadas de Polinomiais, onde esta última é construída a partir de uma base nodal equidistante e pela imposição da partição da unidade. Entretanto estas funções aproximadoras garantem apenas continuidade C0 entre os elementos triangulares, ou seja, a garantia da continuidade do plano tangente não necessariamente é satisfeita. Com o objetivo de anular o termo de integral de linha presente na formulação microestrutural, a hipótese de superfície suave se faz necessária e assim funções de Bézier com continuidade geométrica G1, a qual depende apenas da posição e das normais dos nós nos vértices da malha triangular é utilizada. Para auxiliar na obtenção das coordenadas e das normais nodais para geometrias complexas foi utilizado o software de computação gráfica BlenderTM 2.7, o qual foi acoplado ao programa do MEC elastostático gradiente. Na sequência foi verificada, por meio de exemplos, a suavidade na intersecção entre os elementos triangulares G1 e estes foram comparados com as aproximações de Proriol e Polinomial. Em seguida, as singularidades presentes nas soluções fundamentais foram tratadas através da expansão em série de Laurent aplicada à técnica de subtração de singularidade. Condições necessárias e suficientes para a convergência das expansões em série das soluções fundamentais, estimador do erro para estas expansões, assim como, a correlação matemática entre o tamanho da malha e o parâmetro micromecânico g foram estabelecidos. Expressões explicitas da série de Laurent dos núcleos das integrais singulares e hipersingulares do MEC clássico e não clássico foram apresentadas. A verificação do tratamento da singularidade aplicado a elementos triangulares curvos foi realizada, tanto na direção radial quanto na direção angular. E pôde ser observado que ocorre uma perda de eficiência no tratamento da singularidade na direção angular, devida a presença do efeito de camada limite para elementos curvos distorcidos. Entretanto, este efeito de quase singularidade pode ser amenizado por meio da abordagem micromecânica, uma vez que foi observado menor presença do efeito da camada limite à medida que o parâmetro g é diminuído. Por último, foi desenvolvido um programa na linguagem FORTRAN 11.0, o qual contempla as abordagens clássica e micromecânica com continuidade geométrica G1. Sua validação foi feita por meio de exemplos considerados Benchmarks.
In this work, a micromechanical approach with approximation of geometry solved by Bézier triangular functions that guaranty continuity G1 is inserted to the Boundary element Method (BEM). This formulation is applied in three-dimensional elastostatic problems. The simplified elastic gradient theory proposed by Aifantis, which is a particularization of the general theory of Mindlin is used to consider the microstructural effect. In this theory a variational argument is established to determine all possible boundary conditions, classical and non-classical, for the general boundary value problem. From this argument, the fundamental solution of the gradient elasticity is explicited and by the reciprocal integral identity the boundary integral representation is achieved. In addition to the boundary integral representation for dispacement, a second integral representation regarding its normal derivative is used to make the well-posed boundary value problem. Integral expressions for displacement and stress on internal points are also presented. All kernels in the integral equations are explicitly developed. Curved triangular elements are used for the discretization of the BEM. The approximation of both the geometry and physical parameters is performed by Proriol functions (with spectral characteristics) and by Polynomial functions. The last is built from an equidistant nodal basis enforcing the partition of unity. However these approximating functions ensure only C0 continuity between the triangular elements, that is, the tangent plane continuity assurance is not necessarily satisfied. In order to cancel line integral terms in the microstructural approach, the hypothesis of smooth surface is required and thus Bézier function with geometric continuity G1, which depends only on the position and the normal of the nodes at the vertices of the triangular mesh is used. In this study the computer graphics software called BlenderTM 2.7 is used to assist in obtaining coordinates and normal vectors at nodes when complex geometries are analyzed. BlenderTM 2.7 is coupled to the gradient elastic BEM program. The smoothness of the resulting mesh using G1 elements is compared to Proriol and Polynomial approximations by means of simple examples. The singularities present in the fundamental solutions are treated by employing the expansion in Laurent series and the singularity subtraction technique. Necessary and sufficient conditions for the convergence of expansions in series of fundamental solutions, error estimator for these expansions, as well as the mathematical correlation between the size of the mesh and the micromechanical parameter, g, are established. Explicit expressions of Laurent series of the classical and micromechanical kernels forthe singular and hipersingular BEM integrals are presented. Treatment of singularity, both in the radial direction and in the angular direction, applied to curved triangular elements is verified. It can be observed that there is a loss of efficiency in the treatment of singularity in the angular direction, due to the presence of the boundary layer effect for distorted curved boundary elements. However, this nearly singularity effect could be alleviated by micromechanics approach, since minor boundary layer effect was observed as the parameter g is decreased. Finally, using FORTRAN 11.0 language, a computational code is developed, which includes the classic and micromechanics approach with geometric continuity G1, and its results are validated by means of Benchmark examples.
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Nozères, Claude. "Régime alimentaire du béluga, Delphinapterus leucas, de l'estuaire du Saint-Laurent, Canada, tel que révélé par l'analyse des acides gras du lard." Master's thesis, Université Laval, 2006. http://hdl.handle.net/20.500.11794/18708.

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Une connaissance du régime alimentaire des espèces constitue un élément clé pour la compréhension de l’écologie des espèces. Or, peu de techniques existent afin d’examiner le régime alimentaire contemporain du béluga du Saint-Laurent étant donné le statut précaire de cette population et la rareté de contenus stomacaux chez les individus retrouvés morts. L’analyse des profils d’acides gras dans le lard et dans leurs proies potentielles constitue un outil susceptible de fournir certains indices concernant leur régime alimentaire. C’est donc dans ce but qu’une étude comparative des profils d’acides gras a été menée. Dans une première étape, le profil d’acides gras a été examiné chez environ 60 espèces de proies potentielles du béluga provenant de l’estuaire et du golfe du Saint-Laurent. Cette analyse a révélé la nécessité de considérer les effets des lipides totaux, de la taille, des saisons et des lieux d’échantillonnage lors de l’examen des profils d’acides gras des espèces afin d’améliorer le couplage des profils des proies potentielles avec ceux d’un prédateur tel que le béluga. Les profils d’acides gras du lard ont ensuite été comparés entre les bélugas et quatre espèces de pinnipèdes qui se trouvent dans l’estuaire et le golfe du Saint-Laurent. Les espèces de même que les sexes et classes d’âge ont généralement pu être distingués sur la base des profils d’acides gras. Une gamme d’analyses multivariées ont révélé des différences qui semblaient liées à des acides gras d’origine alimentaire, confirmant ainsi le potentiel de ces techniques dans l’analyse comparative de la diète des mammifères marins. La caractérisation des signatures d’acide gras des proies potentielles et des prédateurs constitue une étape essentielle dans le cheminement menant à une meilleure compréhension de l’écologie alimentaire de ces animaux.
Knowledge of diet is an important element for understanding the ecology of species. Currently, there are few techniques to examine the contemporary diet of St. Lawrence belugas considering the precarious status of the population and the rarity of prey remains in the stomach of stranded individuals. Fatty acid analyses of prey and blubber may provide the tools to indicate diet. It was with this purpose that a comparative study of fatty acid profiles was undertaken. As a first step, about 60 potential prey species for belugas were collected in the Estuary and Gulf of St. Lawrence and were examined for their fatty acid profiles. The analysis revealed the need to consider the effects of lipid content, size, season, and sampling location when evaluating species fatty acid profiles in order to improve evaluations of prey profiles of a predator such as the beluga. Blubber fatty acid analyses were subsequently compared between belugas and four species of pinnipeds that are encountered in the Estuary and the Gulf. Species along with other classes such as sex and age could be distinguished on the basis of their fatty acid signatures. A suite of multivariate analyses confirmed the role of diet-linked fatty acids in differentiating the groups, thereby confirming the potential for these techniques to conduct a comparative analysis of diets among these marine mammals. The characterization of fatty acid signatures of potential prey and predators represents essential steps on the path towards a better understanding of trophic ecology in these animals.
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18

Issa, Alexandra. "Hennes namn var Carmila : En queerteoretisk analys av Joseph Sheridan Le Fanus novell Carmilla." Thesis, Södertörns högskola, Lärarutbildningen, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-31431.

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This dissertation is a text analysis of the short novel Carmilla (1872) by the Irish ghost story-author Joseph Sheridan Le Fanu. It is a close reading analysis where I apply a queer theoretical perspective using Mia Franck’s model to analyze different silence practices in Carmilla. I focus on the female vampire Carmilla and her companion Laura and how they are portrayed in this short novel. I will ask the questions: do the characters Carmilla and Laura show a non-heterosexual relationship, passion and desire? How do they depart from the gender norm and can they be seen as characters who deviate from what society considers ‘normal’ behaviour? And can Carmilla and Laura’s relationship be seen as an example of silenced homosexuality and in what way is it expressed? Carmilla and Laura’s behaviour can certainly be described as queer and it is effective to examine the novella using silence practices through a queer perspective. Many of the practices are written silences. Mostly, its things that the reader realizes before the storyteller Laura does herself. They reveal numerous oddities in the story, taking the form of narrative, camouflaged, performative, ritualized and existential silences. Prominent examples are the way Carmilla hides both her vampiric and lesbian sides which Laura is repelled at in addition to her own lustful and passionate emotions. As a future teacher, one of my most important jobs will be to educate my pupils about democratic values and that all kinds of discrimination should be discouraged. An essay of this sort is one way to educate them in how gender and sexuality can be seen from historical, political and cultural perspectives.
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Bühler, David [Verfasser], Stefan Akademischer Betreuer] Dreizler, Sami K. [Akademischer Betreuer] [Solanki, Wolfgang [Akademischer Betreuer] Schmidt, Laurent [Akademischer Betreuer] Gizon, Manfred [Akademischer Betreuer] Schüssler, Wolfgang [Akademischer Betreuer] Glatzel, and Hardi [Akademischer Betreuer] Peter. "Analysis of small scale solar magnetic fields using Hinode SOT/SP / David Bühler. Gutachter: Sami Solanki ; Wolfgang Schmidt ; Laurent Gizon ; Manfred Schüssler ; Wolfgang Glatzel ; Hardi Peter. Betreuer: Stefan Dreizler." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2014. http://d-nb.info/1054191778/34.

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Møller, Silke. "Do Afghan women need saving? : A Critical Discourse Analysis of Laura Bush’s representation of the women in Afghanistan." Thesis, Malmö universitet, Institutionen för globala politiska studier (GPS), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-45801.

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Do Afghan women need saving? This study focuses on the discourse of the USA’s First Lady Mrs. Laura Bush in the years (2001-2009) and how she represents the women in Afghanistan in the context of the USA-led intervention in Afghanistan. My aim is to understand how the USA intervention can be legitimized through Mrs. Bush’s argumentation of bringing human rights to Afghan women. In the analysis in this thesis, Fairclough’s Critical Discourse Analysis is used in combination with feminist and postcolonial theory to understand her discourse about the women in Afghanistan and how her resulting discourse functions in connection with the USA-led intervention in Afghanistan. The study concludes that Mrs. Bush constructs the Afghan women as in need of help and in connection the USA as the helping hand who have an obligation to save the women in Afghanistan. In combination with strategic use of ‘embedded feminism’ and an oriental discourse Mrs. Bush’s discourse functions to make the USA-led intervention in Afghanistan seem legitimate.
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Lee, Jae-Moon. "A thousand plateaux." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/274259.

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The puzzle known as tangram was the inspiration behind this composition. Just as the seven pieces of the tangram create shapes, seven contrasting musical fragments appear as thematic materials from which to draw sonic imagery. Sapphic Fragments for two sopranos This composition was constructed from “broken” materials - an analogy for Sappho's dismembered poem. These broken materials were arranged in a pointillistic manner. I drew inspiration from M.C. Escher's works to vary thematic fragments of this work. M.O.N.T.A.G.E. for flute, clarinet, violin and cello This work was influenced by the video work, Wantee, by artist, Laure Prouvost. The title, M.O.N.T.A.G.E., is an acrostic, using words that show intimate relations with my composition: Multicolour, Oscillation, Numbers, Television, the Artist, Gleam, Etc. Once Emerged from the Grey of Night for flute, clarinet, horn, violin, viola and cello This sextet consists of numerous fragments with various colours and textures, forming a musical collage. A picture-poem by Paul Klee offered the starting point for this work. Scale-Free Spaces for flute, guitar, viola and cello I drew compositional ideas from the video installation, Irreversible, by artist Norimichi Hirakawa. This quartet was composed of brief fragments of dots, lines and movements. Various fragments were structured in forms of both simplicity and complexity. For the latter, ideas were drawn from the study in randomness, ‘Scale-Free Network’. String Quartet no. 3 This composition consists of four movements. In the first and third movements, the sound of rain drops and images of light through stained glass are explored. The second and fourth movements effect a structural metamorphoses of musical elements. I drew inspiration from Kafka's novella The Metamorphosis. A Thousand Plateaux for orchestra In this orchestral work, a variety of images of both plateaux and movements were invoked. The work was inspired by both the book, A Thousand Plateaux by Gilles Deleuze and Félix Guattari, and the Alhambra palace in Granada, Spain.
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Plumley, Bailey. "Self-Inclusion of the Queer Body in Barbara Hammer's 'Superdyke Meets Madame X' (1975)." Ohio University Honors Tutorial College / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1620157460893929.

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23

Altinkurt, Gader. "Apport de la microdiffraction Laue pour la détermination des contraintes internes dans un superalliage à base de nickel grenaillé : effets de la microstructure et des traitements thermomécaniques." Thesis, Université de Lorraine, 2018. http://www.theses.fr/2018LORR0252/document.

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Ce travail de thèse est consacré principalement à l’étude des relations entre la microstructure, le procédé de grenaillage et les champs de contraintes résiduelles dans le superalliage à base de nickel N18. Pour mettre en exergue le rôle de la microstructure, nous avons tout d’abord fabriqué quatre microstructures modèles de tailles de grains gamma et de précipités gamma' significativement différentes par différents chemins thermiques. Les échantillons ont été ensuite grenaillés par ultrason et enfin soit traités thermiquement ou sollicités en fatigue à chaud. Nous avons étudié les changements microstructuraux et mécaniques induits par chaque étape en s'appuyant sur différentes techniques de caractérisation (MEB, dureté, essais de traction et de fatigue). Nous montrons que la dureté et les propriétés en traction avant grenaillage ainsi que les modifications microstructurales et de dureté après grenaillage sont principalement dépendantes de la taille de précipités gamma'. Des mesures in situ de résistivité électrique ont permis de suivre les cinétiques de dissolution et de précipitation de la phase gamma' au cours de traitements thermiques. Les cinétiques ont été comparées à un modèle de précipitation développé pour l’alliage N18. Dans la suite, nous avons déterminé finement les contraintes résiduelles par diffraction des rayons X en laboratoire avec la méthode des « sin² psi » et au synchrotron avec la microdiffraction Laue couplée à des mesures d’énergies. La sensibilité de la microdiffraction a permis d’appréhender le rôle de la microstructure sur les champs de déformations et de contraintes à l’échelle du micromètre et de différencier la contribution des phases gamma et gamma', qui constitue l’une des principales difficultés de ce travail d’exploitation. Avant grenaillage, la déformation déviatorique est inférieure à 2 x 10-4 quelle que soit la taille de précipités gamma'. À l’issue du grenaillage, un décalage des profils de déformations et de contraintes de 100 µm est observé lorsque l'on compare la microstructure contenant de fins précipités gamma' (200 nm) à celle contenant des précipités gamma' grossiers (2000 nm). Les profils de contraintes obtenus avec la microdiffraction Laue montrent des différences significatives en comparaison à l’état de contraintes planes attendu à cœur de l’échantillon. Enfin, nous montrons qu’à l’issue d’un maintien isotherme ou d’un essai de fatigue interrompu, les déformations déviatoriques introduites par de grenaillage sont relaxées ou redistribuées
This thesis is mainly devoted to the study of the relation between microstructure, shot-peening process and residual stress fields in a N18 nickel-based superalloy. To highlight the effect of the microstructure, four simplified microstructures with significantly different gamma grain and gamma' precipitate sizes were designed using different heat treatments. Samples were then subjected to ultrasonic shot-peening and finally either to isothermal holding or to low-cycle fatigue test. Microstructural and mechanical modifications induced by each step were studied using different characterization techniques (SEM, hardness, tensile and fatigue tests). Hardness and tensile properties prior to shot-peening as well as microstructural and hardness modifications after shot-peening mainly depend on the gamma' precipitate size. In situ electrical resistivity measurements were used to follow gamma' dissolution and precipitation kinetics during heat treatments. The kinetics was compared to a model developed for the N18 alloy. Afterward, residual stresses were determined by conventional X-ray diffraction with the « sin² psi » method and synchrotron Laue microdiffraction coupled with energy measurements. The sensitivity of the microdiffraction technique allowed to understand the effect of the microstructure on strain and stress fields at the micrometer scale and to separate the contribution of gamma phase from that of gamma' phase, which is one of the major difficulties of this analysis. Prior to shot-peening, the deviatoric strain is less than 2 x 10-4 regardless of the gamma' precipitate size. After shot-peening, a shift of 100 µm on strain and stress profiles was observed between microstructures with fine gamma' precipitates (200 nm) and coarse gamma' precipitates (2000 nm). Stress profiles obtained with Laue microdiffraction method showed significant differences compared to the plane stress state expected in the sample. Finally, the deviatoric strains introduced by shot-peening are relaxed or redistributed after an isothermal holding or an interrupted fatigue test
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Varin, Mathieu. "Cartographie de trois fonctions écologiques des milieux humides à l’aide d’indicateurs spatiaux dans un contexte d’aide à la décision." Mémoire, Université de Sherbrooke, 2013. http://savoirs.usherbrooke.ca/handle/11143/81.

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Les fonctions écologiques des milieux humides permettent de fournir des biens et services écologiques utiles à la société, dont plusieurs sont critiques à notre survie. Par contre, ces milieux humides subissent souvent de nombreuses perturbations anthropiques modifiant leur capacité à fournir ces biens et services écologiques. Incidemment, leurs fonctions écologiques sont dégradées. Elles représentent l’élément clef dans la démarche proposée pour évaluer l’état des milieux humides. Le projet a débuté par l’analyse des sites d’étude au Québec, soient les bassins versants des rivières Yamaska et Bécancour. Par la suite, les fonctions écologiques ont été sélectionnées (support d’habitats fauniques, régulation des débits de crues et rétention des sédiments) et caractérisées pour leur associer des indicateurs spatiaux mesurant leurs caractéristiques selon le développement durable. Une approche multiéchelle a été intégrée pour diviser le territoire lors de la cartographie des indicateurs spatiaux afin de poser un diagnostic (sous-bassin : niveau stratégique) et cibler l’intervention (microbassin : niveau tactique). L’approche multitemporelle a permis, ensuite, de cartographier ces indicateurs pour différents horizons temporels : la situation historique de 1984, l’état actuel de 2011 et deux scénarios de simulation en 2050, soient une vision pessimiste et optimiste quant à la gestion des milieux humides. Ces analyses spatiales ont été combinées pour proposer un outil d’aide à la décision permettant de cibler des secteurs problématiques. En considérant les trois fonctions écologiques, une tendance générale est constatée pour chaque bassin versant. C’est à l’ouest de la rivière Yamaska, près de Saint-Hyacinthe, et dans la portion est de la rivière Bécancour, autour de Thetford Mines, que les fonctions écologiques procurées par les milieux humides sont en déficit. De plus, les fonctions du support d’habitats fauniques et de régulation des débits de crues comportent le plus grand nombre de secteurs problématiques pour les bassins versants des rivières Yamaska et Bécancour, respectivement. Le développement d’indicateurs spatiaux selon des approches multiéchelle et multitemporelle a permis de proposer une solution innovante pour la gestion des bassins versants en tenant compte des fonctions écologiques procurées par les milieux humides. De plus, l’intégration de l’aspect de durabilité est un avantage considérable dans l’élaboration d’un outil d’aide à la décision pour les intervenants.
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Varin, Mathieu. "Cartographie de trois fonctions ??cologiques des milieux humides ?? l???aide d???indicateurs spatiaux dans un contexte d???aide ?? la d??cision." Mémoire, Universit?? de Sherbrooke, 2013. http://savoirs.usherbrooke.ca/handle/11143/81.

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Les fonctions ??cologiques des milieux humides permettent de fournir des biens et services ??cologiques utiles ?? la soci??t??, dont plusieurs sont critiques ?? notre survie. Par contre, ces milieux humides subissent souvent de nombreuses perturbations anthropiques modifiant leur capacit?? ?? fournir ces biens et services ??cologiques. Incidemment, leurs fonctions ??cologiques sont d??grad??es. Elles repr??sentent l?????l??ment clef dans la d??marche propos??e pour ??valuer l?????tat des milieux humides. Le projet a d??but?? par l???analyse des sites d?????tude au Qu??bec, soient les bassins versants des rivi??res Yamaska et B??cancour. Par la suite, les fonctions ??cologiques ont ??t?? s??lectionn??es (support d???habitats fauniques, r??gulation des d??bits de crues et r??tention des s??diments) et caract??ris??es pour leur associer des indicateurs spatiaux mesurant leurs caract??ristiques selon le d??veloppement durable. Une approche multi??chelle a ??t?? int??gr??e pour diviser le territoire lors de la cartographie des indicateurs spatiaux afin de poser un diagnostic (sous-bassin : niveau strat??gique) et cibler l???intervention (microbassin : niveau tactique). L???approche multitemporelle a permis, ensuite, de cartographier ces indicateurs pour diff??rents horizons temporels : la situation historique de 1984, l?????tat actuel de 2011 et deux sc??narios de simulation en 2050, soient une vision pessimiste et optimiste quant ?? la gestion des milieux humides. Ces analyses spatiales ont ??t?? combin??es pour proposer un outil d???aide ?? la d??cision permettant de cibler des secteurs probl??matiques. En consid??rant les trois fonctions ??cologiques, une tendance g??n??rale est constat??e pour chaque bassin versant. C???est ?? l???ouest de la rivi??re Yamaska, pr??s de Saint-Hyacinthe, et dans la portion est de la rivi??re B??cancour, autour de Thetford Mines, que les fonctions ??cologiques procur??es par les milieux humides sont en d??ficit. De plus, les fonctions du support d???habitats fauniques et de r??gulation des d??bits de crues comportent le plus grand nombre de secteurs probl??matiques pour les bassins versants des rivi??res Yamaska et B??cancour, respectivement. Le d??veloppement d???indicateurs spatiaux selon des approches multi??chelle et multitemporelle a permis de proposer une solution innovante pour la gestion des bassins versants en tenant compte des fonctions ??cologiques procur??es par les milieux humides. De plus, l???int??gration de l???aspect de durabilit?? est un avantage consid??rable dans l?????laboration d???un outil d???aide ?? la d??cision pour les intervenants.
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Hofmann, Felix. "Probing the deformation of ductile polycrystals by synchrotron X-ray micro-diffraction." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:4a5db5b9-1673-40bf-a25f-2e09a572a108.

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Microscopic beams of penetrating synchrotron radiation provide a unique tool for the analysis of material structure and deformation. This thesis describes my contributions to the development of new synchrotron X-ray micro-beam diffraction experimental techniques and data interpretation, and the use of experimental results for the validation of material deformation models. To study deeply buried material volumes in thick samples, the micro-beam Laue technique was extended to higher photon energies. Through-thickness resolution was achieved either by a wire scanning approach similar to Differential Aperture X-ray Microscopy (DAXM), or by applying tomographic reconstruction principles to grain-specific Laue pattern intensity. Both techniques gave promising first results. For reliable micro-beam Laue diffraction measurements of elastic strains in individual grains of a polycrystal, understanding of the error sources is vital. A novel simulation-based error analysis framework allowed the assessment of individual contributions to the total measurement error. This provides a rational basis for the further improvement of experimental setups. For direct comparison of experimental measurements and dislocation dynamics simulations, diffraction post-processing of dislocation models in two and three dimensions was developed. Simulated diffraction patterns of two-dimensional dislocation cell/wall type structures captured correctly some of the features observed experimentally in reciprocal space maps of a large-grained, lightly deformed aluminium alloy sample. Crystal lattice rotations computed from three-dimensional dislocation dynamics simulations of a Frank-Read source showed anisotropic orientation spread similar to that observed in micro-beam Laue experiments. For the experimental study of crystal lattice distortion, a novel technique was proposed that combines micro-beam Laue diffraction with scanning white-beam topography. Diffraction topography allows the study of lattice rotation at scales smaller than the scanning beam size. The new technique makes it possible to apply classical topography methods to deformed samples.
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Commans, Julie. "Le jeu du père : le père-narrateur dans le roman français contemporain." Thesis, Université Clermont Auvergne‎ (2017-2020), 2017. http://www.theses.fr/2017CLFAL017.

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Rares sont les occasions pour le père de faire entendre sa voix dans le roman français contemporain. Alors que le récit de filiation a pris une ampleur sans précédent dès les années 1980, offrant aux fils et aux filles la possibilité de questionner leur ascendance, la figure paternelle est de longue date sommée de garder le silence. Le fait n’est pas nouveau : la littérature fut à maintes reprises le témoin d’une paternité tenue à distance de l’intimité familiale, victime de l’image tenace d’un patriarche, autoritaire et injuste, progressivement dépossédée de ses pouvoirs par l’Histoire. À l’approche du XXIe siècle cependant, les sciences humaines manifestent un intérêt soudain pour le sujet ; considérant le silence du père, la sociologie, la psychologie, l’histoire mais aussi la littérature s’interrogent : quelle place, quel rôle et finalement quelle identité doivent être aujourd’hui accordés au père ? Parmi la rumeur grandissante, le principal intéressé, pressé de questions, peine à se hisser sur le devant de la scène pour prendre la parole. Il convient dès lors de prêter attention à l’exception du père-narrateur et d’enquêter sur les modalités d’une telle émergence dans le roman contemporain. L’analyse appuyée sur un corpus de romans de quatre écrivains – Philippe Forest, Laurent Mauvignier, Gisèle Fournier et Sylvie Gracia –, mêlant écrits fictifs et autobiographiques, a permis de définir les caractéristiques d’un phénomène inédit introduisant une réflexion nouvelle sur la paternité, en ce qu’elle répond de l’incertitude de l’individu contemporain, mais aussi de la paternité littéraire et des enjeux de l’écriture contemporaine. L’étude pose pour cela dans un premier temps les contextes historiques et génériques de la paternité en confrontant les points de vue proposés par les sciences humaines et ceux résultant de l’approche littéraire. La structure de la narration paternelle est ensuite observée de manière à comprendre comment advient la parole du père et le fonctionnement spécifique de celle-ci. Enfin la dernière partie s’attarde sur la singularité de la voix paternelle et sur ce qui, visant à rendre compte du réel, s’apparente à un jeu littéraire sans fin, entraînant côte à côte, écrivain, personnages et lecteur
In the contemporary French novel, the father has few opportunities to be heard. While there have been an increasing number of stories about filiation since the 1980's, giving sons and daughters the possibility of questioning their ancestry, the father figure remains silent. Nothing is new here: literature often shows the father being kept away from the private sphere of family life, the father being a victim of the enduring patriarchal image and of his lost authority. At the turn of the 21st century, however, the humanities and social sciences suddenly began to take an interest in the topic. Looking at the father's silence, sociology, psychology, history, and also literature ask the question: what place, what role, and, in the end, what identity should be given to the father? In the midst of this growing discussion, the key player pressed by questions struggles to make his way into the foreground and take the floor. If eventually he introduces himself as a narrator, this should be noted and the forms of such an emergence in the contemporary novel should be investigated. An analysis based on the novels of four writers – Philippe Forest, Laurent Mauvignier, Gisèle Fournier et Sylvie Gracia – blending fictional and autobiographical works, allows us to define the features of an unprecedented phenomenon leading to new ideas about being a father today in terms of how it reflects the uncertainty of the individual in society, and also about the authorship of the work (“paternity”) and its issues in contemporary writing. This study first lays out historical and generic contexts of fatherhood by addressing the points of view offered by the social sciences and those derived from the literary approach. The structure of the paternal narration is then observed in such a way to allow an understanding of what's behind the father's words and how they work. Finally, the last chapter focuses on the singularity of the paternal voice and on that which, attempting to take account of reality, lends itself to an endless literary game, carrying away author, characters, and readers
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Saim, Norashikin. "The odor components of the defense mechanism of the "green worm", Amynthas hupeiensis and wheat insect repellent in bay leaves, (Laurus nobilis, L.)." 1985. http://hdl.handle.net/2097/27576.

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Kuo, Chia-hui, and 郭嘉惠. "A Study of picture book'' s Style--An Analysis by Babette Cole and Lauren Child." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/g79gv9.

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碩士
南華大學
文學系
101
Great Britain has been the center of development for children’s literature. Many picture books that won the prize were translated in the early period of Taiwan. The activity also brings domestic picture book development. Both Babette Cole and Lauren Child are British’s picture book authors. Both of them have won the highest honor of the British book industry award for Kate Greenaway. The books from both of them were well recognized in Euro or Taiwan and stand high in the bestsellers list for a long time with high popularity no matter elder or younger readers.     The study mainly focuses on sixteen translated picture books with self-author and self-portrait each from Cole and Child as research subject. The main structure firstly researches the creative background and philosophy in depth. Secondly, through thorough reading, by comparison of two major themes of literary and graphic arts from their picture books, the study tries to conclude the unique characteristics from books and the real reasons why they get so many popularity and favorite. Finally, the study’s conclusion may be used as a reference for picture book creators.     This thesis is divided into five chapters. The first chapter is introduction section that depicts the study result of the motivation and purpose from two British’s picture book authors and summarizes the results of previous similar papers and research methods and procedures. The second chapter is about life experience and creative vision and artifacts. By understanding the living background as well as creative vision of Cole and Child, the study then introduces the artifacts and analyzes the main themes. The third chapter is the art of literature. The books from two authors are then compared and analyzed by element of literature with 1) the story development, 2) role shaping, 3) background, 4) viewpoints. The fourth chapter is about the art of image. By creative media and the usage of techniques from two authors, the study summarizes visual style, then explores the presentation of layout from picture books to analyze the characteristics of managing the overall layout. Lastly, dig into the relationship between graph and text, graphic configuration, text arrangement to summarize the interaction between graph and text from picture books. The fifth chapter is the conclusion section. Picture books are composed by text and image closely. The study concludes the unique picture book style and the reason of popularity from Cole and Child by analyzing and comparing through literature and graphic art. It is hoped that the character can be used as reference from picture book creators in the near future and create an atmosphere to appeal readers from the picture books’ styles.
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Desmarais, Philippe T. "Logements insalubres en contexte pluriethnique : étude de cas et pistes d'intervention pour le quartier Norgate dans l'arrondissement Saint-Laurent à Montréal." Thèse, 2016. http://hdl.handle.net/1866/13995.

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Ce mémoire explore le rôle du logement dans l'expérience migratoire des nouveaux et nouvelles arrivantes à Montréal et l'impact de celui-ci sur les premières années d'installation, en fonction des caractéristiques socioculturelles des individus. Pour ce faire, une étude collaborative a été menée sur le cas spécifique du quartier de Norgate, situé en plein cœur de l'arrondissement Saint-Laurent. Norgate est un quartier où se produit un renouvellement constant de locataires d'origine immigrante en provenance des quatre coins du monde, et où subsistent d'importants problèmes de pauvreté. En se penchant sur ce milieu de vie et sur les conditions d'habitat de ses résident-e-s, nous avons constaté à quel point un nombre important de locataires vivaient dans des logements en mauvais état, et parfois même dans de graves conditions d'insalubrité. Nous avons cherché à comprendre comment un tel espace urbain pouvait en venir à être aussi dégradé et quels étaient les rôles et responsabilités des différents paliers étatiques face à une telle situation. À travers ce processus, nous avons exploré l'ensemble des possibilités d'action proposées par les différents acteurs (institutionnels, communautaires, résidentiels) ayant un potentiel pouvoir d'agir dans le quartier. Ce mémoire montre comment la problématique des logements dans l'espace urbain est liée à une multitude de facteurs interreliés et qui s'influencent mutuellement, d'où la nécessité d'une approche systémique dans l'analyse du champ de l'anthropologie urbaine. Il cherche également à montrer en quoi un mouvement urbain efficient nécessite un partenariat rigoureux entre les différents acteurs agissant sur le territoire, dans une logique de compréhension et de respect de la diversité des tactiques.
This thesis explores the role that housing plays in the migratory experience of newcomers in Montreal as well as its impact on the first years of settling, taking into account their social and cultural characteristics. To accomplish this, a collaborative study has been conducted on the specific case of the neighborhood "Norgate", situated in the heart of the Saint-Laurent bourrough. Norgate is a neighborhood in which we can observe a constant renewal of immigrant tenents from around the world, as well as persisting problems of poverty. Taking a closer look at this social environment and the living conditions of its residents, we have ascertained the extent to which poor, and sometimes even unsanitary housing is the norm. We sought to comprehend how an urban space could come to be so degraded, and to determine the roles and responsibilities of various levels of government in the face of such a situation. Through this process, we have explored the ensemble of possible actions proposed by different actors (institutional, community organizations, and residents) that potentially have influence within the neighborhood. This thesis shows how the problem of housing in urban spaces is related to a multitude of inter-linked factors that are mutually influencing each other, and that thus a systemic analysis and approach in the field of urban anthropology is necessary. It also seeks to show that an effective urban movement necessitates a rigourous partnership between the different actors operating within a given territory, in the perspective of understanding and respecting diversity of tactics.
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Cusson, Edith. "Patrons de distribution des crustacés planctoniques dans le fleuve Saint-Laurent." Thèse, 2011. http://hdl.handle.net/1866/6173.

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La recherche porte sur les patrons de distribution longitudinale (amont-aval) et transversale (rive nord - rive sud) des communautés de crustacés planctoniques qui ont été analysés le long du fleuve Saint-Laurent entre le lac Saint-François et la zone de transition estuarienne, à deux hydropériodes en mai (crue) et en août (étiage). Les données zooplanctoniques et environnementales ont été récoltées à 52 stations réparties sur 16 transects transversaux en 2006. Au chapitre 1, nous présentons les principaux modèles écosystémiques en rivière, une synthèse des facteurs influençant le zooplancton en rivières et les objectifs et hypothèses de recherche. Au chapitre 2, nous décrivons la structure des communautés de zooplancton dans trois zones biogéographiques du fleuve et 6 habitats longitudinaux, ainsi que les relations entre la structure du zooplancton et la distribution spatiale des masses d’eau et les variables environnementales. Au chapitre 3, nous réalisons une partition de la variation des variables spatiales AEM (basées sur la distribution des masses d’eau) et des variables environnementales pour évaluer quelle part de la variation du zooplancton est expliquée par les processus hydrologiques (variables AEM) et les conditions locales (facteurs environnementaux). Le gradient salinité-conductivité relié à la discontinuité fleuve-estuaire a déterminé la distribution à grande échelle du zooplancton. Dans les zones fluviales, la distribution du zooplancton est davantage influencée par la distribution des masses d’eau que par les facteurs environnementaux locaux. La distribution des masses d’eau explique une plus grande partie de la variation dans la distribution du zooplancton en août qu’en mai.
The research aims to determine the distribution patterns of crustacean plankton along the longitudinal (west-east) and transversal (north shore - south shore) axes of the St. Lawrence River between Lake Saint-François and the estuarine transition zone, during two hydroperiods in May (high discharge) and August (low discharge). The zooplankton samples and the environmental data were collected at 52 stations distributed along 16 transversal transects in 2006. In chapter 1, we present the theoretical concepts of river ecosystem models, and a synthesis on the generative processes driving zooplankton spatial patterns in rivers. We also present our research objectives and hypotheses. In chapter 2, we describe spatial patterns of the zooplankton community structure in three biogeographic zones of the St. Lawrence and 6 longitudinal habitats, together with the relationships between zooplankton spatial structure and water masses spatial distribution and environmental characteristics. In chapter 3, we perform a variation partitioning procedure on spatial variables AEM (based on water masses spatial distribution) and environmental variables in order to assess how much of the zooplankton variation is explained by hydrological processes (AEM variables) and local conditions (environmental factors). The salinity-conductivity gradient related to the fluvial-estuary discontinuity determines the large-scale spatial patterns of the crustacean zooplankton. In the fluvial zones, the zooplankton distribution patterns are more influenced by the water masses spatial structure than by local environmental factors. The spatial distribution of the water masses explained more of the spatial structure of zooplankton communities in August than in May.
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32

Mello, Elenice Schmitz. "Horizontes da interatividade na arte digital: o exemplo de Christa Sommerer e Laurent Mignonneau." Master's thesis, 2013. http://hdl.handle.net/1822/29107.

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Dissertação de mestrado em Tecnologia e Arte Digital
Com a tecnologia presente em nosso cotidiano as pessoas estão cada vez mais habituadas ao seu uso. Sendo assim, a tarefa de lidar com computadores, periféricos e softwares precisa cada vez menos ser explicada ou ensinada. Com isso, a participação do público em instalações ou mesmo em obras de arte parece ter-se tornado mais natural e fluída. Foram selecionados os artistas Christa Sommerer e Laurent Mignonneau como foco de estudo deste trabalho. Analisou-se suas obras, técnicas e linha de criação. Além disso, a arte sempre foi um tema que instigou a humanidade, que acompanha sua história. Como não poderia ser diferente, hoje em dia, tem-se uma ramificação da arte: a Arte Digital. Buscou-se compreender os conceitos intrínsecos nesse nicho da arte bem como entender de forma cronológica os caminhos que levaram essa arte a chegar aqui. Abordou-se ainda neste projeto, a questão da experiência do usuário, evidenciando as sensações que o artista deseja transmitir ou mesmo como a obra havia sido idealizada e como tomou um rumo diferente. Explorar-se-á o assunto da relação homem/máquina e sua evolução no decorrer dos anos. Mesmo que não exista uma única forma de criação, esta pesquisa será uma importante ferramenta para artistas iniciantes, que ainda estão a dar seus primeiros passos. E como resultado final desta dissertação, apresentam-se as distinções entre a criação de obras convencionais e de obras digitais. Entendendo melhor o processo como um todo.
With the technology in our everyday life, people are increasingly getting used to it. Thus, the task of dealing with computers, peripherals and software don´t need to be explained or taught. With this, the public paticipation in installations or even in works of art seems to have become more natural and fluid. It was selected the artists Christa Sommerer and Laurent Mignonneau as the focus of the study of this work. It was analyzed their works, techniques and line creation. Moreover, art has always been an issue that instigated humanity, it follows his history. It couldn´t be different today, when exists a branch of art: the Digital Art. It was tried to understand the concepts inherent in this niche of the art as well as understand chronologically the paths that led this art to get here. It is also addressed in this project, the issue of user experience, highlighting the feelings that the artist wishes to convey or even how the work was planned and how it has taken a different turn. It will explore the subject of the man / machine and its evolution over the years. Even if there is not only one form of creation, this research will be an important tool for new artists, who are making their first steps. And as a final result of this thesis, we present the distinctions between creating works of conventional arts and digital arts, trying to understand the whole process better.
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33

Moser, Stefan. "Analysing smallholders behaviour on Sumatra: An ex ante policy analysis and investigation of experiments external validity under consideration of risk." Doctoral thesis, 2015. http://hdl.handle.net/11858/00-1735-0000-0022-606B-6.

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34

Turgeon, Samuel. "Modélisation de l'utilisation de l'habitat du béluga du Saint-Laurent en fonction de ses proies à l'embouchure de la rivière Saguenay et à la baie Sainte-Marguerite." Thèse, 2012. http://hdl.handle.net/1866/6990.

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Le béluga du Saint-Laurent est une espèce menacée au Canada et protégée par la Loi sur les espèces en péril du Canada. La détermination des fonctions biologiques de ses habitats essentiels est nécessaire afin d’assurer le rétablissement de la population. Parcs Canada a entamé en 2009 un suivi des proies du béluga dans deux de ses aires de fréquentation intensive situées dans le Parc marin du Saguenay–Saint-Laurent : l’embouchure de la rivière Saguenay et la baie Sainte-Marguerite. L’étude de l’abondance et de la distribution des proies est réalisée par sondage hydroacoustique le long de transects à l’aide d’un échosondeur multifréquences. Un protocole d’observations systématiques du béluga est mené simultanément aux sondages hydroacoustiques à partir de sites terrestres. Le premier objectif de cette étude est de développer la méthodologie concernant le traitement, la classification et la cartographie des données hydroacoustiques échantillonnées. L’objectif principal consiste à déterminer si l’abondance et la distribution des proies pélagiques ont une influence sur l’utilisation de ces deux habitats par le béluga. La cartographie de la biomasse relative de poissons a été réalisée pour la couche de surface, la couche en profondeur et pour l’ensemble de la colonne d’eau par krigeage ordinaire pour les deux habitats pour les 29 transects. À la baie Sainte-Marguerite, le nombre de bélugas observés augmente avec la biomasse relative des proies en surface et en profondeur. À l’embouchure de la rivière Saguenay, les résultats n’ont pas été concluants. Les résultats suggèrent que l’alimentation pourrait être l’une des fonctions biologiques de la baie Sainte-Marguerite.
The St. Lawrence beluga is a threatened species in Canada and protected by the Species at Risk Act in Canada. Determining the biological functions of its critical habitat is needed to ensure the recovery of the population. Parks Canada began in 2009 a monitoring of beluga preys in two of its areas of intensive use located in the Saguenay–St. Lawrence Marine Park: the Saguenay River mouth and the Sainte-Marguerite bay. The study of the abundance and distribution of prey is achieved by hydroacoustic survey along transects using a multifrequency echo sounder. A systematic observation protocol of the beluga is conducted simultaneously with hydroacoustic surveys from land-based stations. The first objective of this study is to develop the methodology for the processing, classification and mapping of these hydroacoustic data. The main objective is to determine whether the abundance and distribution of pelagic prey influence the use of these two habitats by beluga. The mapping of the fish relative biomass was conducted for the surface layer, the depth layer and the entire water column by ordinary kriging for the two habitats for the 29 transects. At Sainte-Marguerite bay, the number of whales observed increases with fish relative biomass in the surface and deep layers. At the Saguenay River mouth, the results are not conclusive. The results suggest that feeding may be one of the biological functions of the Sainte-Marguerite bay.
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35

Chang, Meng-Chieh, and 張孟傑. "The Analysis and Comparison of Joseph Jean-Baptiste Laurent Arban and Herbert Lincoln Clarke Trumpet Studies Based on Variations on “The Carnival of Venice”." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/12395163539109551004.

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碩士
國立臺中教育大學
音樂學系碩士班
101
The purpose of writing this thesis is to discuss and compare the two different versions of "The Carnival of Venice", composed respectively by the Romantic School trumpeters J. B. Arban and H. L. Clarke. It is also important analyzing the trumpet techniques to confirm whether Arban and Clarke's teaching methods written in their teaching materials are practically used in these works. Solutions are also provided to overcome the difficulties might be faced when performing these works. In addition, the main ideas of Arban and Clarke's trumpet pedagogy are presented in this thesis. Also, the practical applications of the exercises in the etudes can be found by analyzing and practicing "The Carnival of Venice”. This thesis consists of five chapters, including Chapter One- Introduction, Chapter Two- Biography of the Composers and composition background of these two pieces, Chapter Three- Analysis of the Work, Chapter Four- The Analysis and Comparison of J. B. Arban and H. L. Clarke Trumpet Teaching Material based on Variations on “The Carnival of Venice”, and the Conclusion is written in the Chapter Five.
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36

Milmore, Tatum. "Les Iroquoiens de Droulers/Tsiionhiakwatha et le cristal de quartz." Thèse, 2014. http://hdl.handle.net/1866/12540.

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Parmi la grande quantité de témoins culturels découverts sur le site Droulers/Tsiionhiakwatha (BgFn-1), la pierre taillée et polie forme un assemblage bien modeste. Les Iroquoiens de Droulers ont habité un village semi-permanent daté du Sylvicole supérieur, plus précisément entre l’an 1430 et 1500 ap. J.-C. Ils ont fabriqués des grattoirs, des pointes de flèches, des forets, des polissoirs et des meules à mains, en plus d’outils en quartz hyalin dont la fonction n’est pas bien définie. Parmi les 3595 objets lithiques, nous trouvons 18 outils et 1085 déchets de taille en cristal, ce qui représente près de 30% du total. Le quartz hyalin fut utilisé durant la préhistoire québécoise, mais jamais en aussi grande quantité que sur Droulers. Nous présentons la chaîne opératoire du quartz hyalin, de son extraction à son rejet sur les sites archéologiques. Nous explorons également son utilisation et sa symbolique chez les habitants du village Droulers, une enquête basée sur des données archéologiques et ethnographiques des Amérindiens actuels et de ceux de la période de Contact du nord-est de l’Amérique du nord.
Among the large number of artefacts found on the Droulers/Tsiionhiakwatha Iroquoian village (BgFn-1), the assemblage of stone tools is very small. The Iroquoians at Droulers produced scrapers, arrowheads, drills, whetstones and manos, and also shaped tools with crystal quartz. Among the 3595 lithic objects, we find 18 tools and 1085 pieces of debitage in crystal quartz, which compose over 30% of the total lithic assemblage. Cristal quartz was worked during Québec prehistory, but never to this extent. This thesis is about the chaîne opératoire of crystal quartz and its uses throughout prehistory of Québec and among prehistoric Iroquoians.
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37

Laufer, Georg [Verfasser]. "Untersuchung der Transkriptionsmuster von HERV-W-env Loci bei Patienten mit Multipler Sklerose sowie gesunden Kontrollen und Analysen zur Herkunft von MSRV-Sequenzen / vorgelegt von Georg Laufer." 2008. http://d-nb.info/1006821570/34.

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38

Daňková, Andrea. "Genderová analýza vývoje ženských hrdinek v animované tvorbě Walta Disneyho." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-405760.

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The thesis addresses analysis of stories and narrative in relation to the subject of gender. This analysis primarily deals with fairy tale The Beauty and the Beast by Disney. The first part is about general theoretical basis for my thesis and about the most important authors in this field. Archetypes and logocentrism topics are dealt with partially as well. The foundations of the first part are however literary and motion-picture feministic theories, also the concept of the myth of beauty. In the practical part sequences of the The Beast and the Beauty are studied. Findings described in theoretical part is utilized here and the marked and subtle influence of androcentric culture on style and content of the story is shown.
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39

Boisvert, Marie-Ève. "L’industrie osseuse des Iroquoiens du site Mailhot-Curran (BgFn-2) : une étude des déchets de fabrication." Thèse, 2015. http://hdl.handle.net/1866/16078.

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Bien que l’os soit une matière première ayant joué un rôle essentiel au sein des activités quotidiennes des Iroquoiens du Saint-Laurent, il existe à ce jour très peu d’analyses systématiques de l’outillage en os et des débris de fabrication retrouvés en Iroquoianie. Afin de pallier ces lacunes, ce mémoire de maitrise porte sur l’analyse des vestiges en os ouvragés récupérés sur le site villageois Mailhot-Curran (BgFn-2), occupé durant le Sylvicole supérieur tardif par une communauté iroquoienne du Saint-Laurent. Plus précisément, l’étude consiste à analyser l’industrie osseuse en portant une attention particulière aux déchets de fabrication. Cet examen attentif a pour principal objectif de documenter les modes de gestion et de sélection de la matière première ainsi que d’améliorer la compréhension des techniques préhistoriques employées pour la fabrication des objets en os. Au moyen d’analyses technologiques, zooarchéologiques et tracéologiques, il sera possible de classifier les déchets de fabrication, de documenter leur origine technologique et, ultimement, de reconstituer un certain nombre de chaines opératoires. Une étude détaillée de la distribution spatiale des artéfacts permettra également de mieux comprendre l’organisation des activités dans l’espace villageois. Ce mémoire a aussi pour objectif de fournir des balises méthodologiques et empiriques relatives à l’étude des déchets de fabrications en os, afin de démontrer la pertinence de considérer ces derniers dans la compréhension des systèmes socioéconomiques et culturels.
The St. Lawrence Iroquoians were very talented producers of bone tools of all kinds but little is known about the ancient technologies involved in the manufacture of these objects. The relevance of this study arises from the fact that there are significant methodological and theoretical gaps in the analysis of the bone objects produced by St. Lawrence Iroquoians. The aim of this thesis is to provide some answers to those specific gaps of information. This research involves various analyses which are characteristic of technological approaches, and zooarchaeological and use-wear methods. These particular methods will allow me to examine and understand more accurately the past technologies associated with St. Lawrence Iroquoians bone tool industries. Through the analysis and classification of the by-products, debris, blanks, rough-outs and finished objects, I hope to provide a method for understanding the sequence underlying the production of bone tools (procurement, selection, treatment, debitage, shaping, finishing, etc.) and to evaluate the investment made in the procurement and selection of the raw materials. A spatial distribution analysis is carried out to better understand the context for the planning and manufacture of bone tools within the village space. The main purposes of this study are to present methodological guidelines regarding the classification of bone refuse and by-products; to reveal morphological and technological characteristics of these archeological remains through macrosopic and microscopic obsevations, and to provide an empirical model adapted to the analysis of the chaines opératoires leading to distinct categories of bone refuse.
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40

Crépin, Magali. "Étude de «marqueurs d’activités» au sein de deux populations historiques de la Vallée du Saint Laurent : analyses des observations macroscopiques et essais d’interprétations en lien avec des milieux contrastés (urbain versus rural)." Thèse, 2017. http://hdl.handle.net/1866/20019.

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41

Astapencov, Neli. "Proměny genderových archetypů ve filmu Hořký měsíc." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-326358.

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The thesis deals with gender analysis in films studying metamorphoses of archetypes in film Bitter Moon directed by Roman Polanski. The methodical and theoretical sections of the thesis analyse the influence of archetype changes of film characters in gender roles. The thesis identifies and analyses mainly woman film characters appearing in some classical feminist texts, feminist film theoretical and critical articles, in some psychoanalytical works, in dramatheraphy and film science. The sources mentioned above became primary resource materials for our archetypal research. The analysis of each of the film character is focused on the most distinctive archetype with respect to its metamorphosy. Apart from the archetype research the thesis is marginaly concerned with problems linked to the female ideal and her sexuality usually portrayed in an unalterable way, and archetypal patterns are in such a way transmitted to audiences through femininity and masculinity in the context of gender roles. Keywords: archetype, Roman Polanski, Laura Mulvey, Annis Pratt, cinematic archetypal coherence, feminist film criticism, film narrative analysis, archetypal masculinity, archetypal femininity.
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42

Chapdelaine, Maude. "L’exploitation de la faune par les Iroquoiens : l’alimentation carnée des habitants du site McDonald (BgFo-18)." Thèse, 2018. http://hdl.handle.net/1866/23609.

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This thesis explores patterns of faunal exploitation habits at the McDonald site, in the Saint-Anicet area during the Late Woodland period. The main goal is to determine the importance of wild game in the Iroquoian economical system which is based on the balance of fishing, hunting and horticulture. The result of the faunal analysis shows that White-Tailed Deer, North American Black Bear and North American Beaver are the most important taxa contributing to the subsistence economy of the inhabitants of the site. This was determined by standard zooarchaeological methods, including calculation of the number of identified specimens (NISP), the minimum number of individuals (MNI), meat weight (MW) and ethnohistorical data. This thesis also discusses the spatial distribution of animal skeletal remains, comparing meat consumption patterns within each family unity inside the longhouses and within and between each longhouse. This comparison shows that faunal remains are mostly located in the central alignment of longhouses and are homogeneously distributed. The taxa distributed within the longhouses suggest relatively equalitarian access to animal resources. Analysis of the bone concentrations shows a collaborative tendency between family units within the community. Furthermore, the faunal assemblage tends to show an annual occupation of the site. Sedentary occupation of the site is also supported by ceramic analysis and cultigen analysis. Finally, we compare the mammal NISP and MNI of the McDonald's site with seven other contemporaneous archaeological sites from the region. This comparison shows that mammalian resources declined in importance in the Iroquoian diet between the beginning of the 14th century and the first part of the 16th century, probably due to the adoption of horticulture.
Ce mémoire porte sur l'exploitation de la faune par les habitants du site McDonald de la région de Saint-Anicet. L'objectif principal est de caractériser la place des mammifères dans l’économie mixte des Iroquoiens du Saint-Laurent à un moment où l’horticulture gagne en popularité. L’étude de l’assemblage faunique a permis de déterminer que le cerf de Virginie, l’ours noir et le castor du Canada sont les principaux taxons mammaliens qui contribuent de façon économique, technologique et symbolique à l’économie de subsistance des habitants du site McDonald. Cette étude a été menée en intégrant des statistiques descriptives propres à la zooarchéologie telles que le nombre de restes déterminés (NRD), le nombre minimal d’individus (NMI) et le poids de viande (PV) avec des sources d’informations connexes telles que des documents ethnohistoriques, des guides fauniques et des statistiques gouvernementales. Ce travail utilise également l’analyse de la distribution spatiale des restes squelettiques qui montre une répartition des matières dures animales majoritairement alignée dans l’axe central des maisons-longues. La distribution spatiale des taxons montre quant à elle une homogénéité dans la dispersion des animaux entre les maisons-longues, ainsi qu’une répartition relativement égalitaire des ressources carnées entre les unités familiales. L’analyse des concentrations révèle même un esprit de collaboration entre les unités familiales contiguës. De plus, le spectre de faune tend à démontrer une occupation annuelle du site, ce qui corrobore l’analyse céramique et l’analyse des cultigènes. Finalement, en comparant le NRD et le NMI mammalien du site McDonald avec sept autres sites contemporains, l’analyse faunique démontre que les ressources mammaliennes sont en décroissance dans l’alimentation des Iroquoiens entre le début du 14e siècle et la première moitié du 16e siècle, période qui correspond justement à l’essor de l’horticulture (maïs, haricot, courge) au sein de la diète iroquoienne, ce qui caractérise l’économie mixte de la période du Sylvicole supérieur.
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43

Smit, Joukje Anneke. "Koliha–Drazin invertibles form a regularity." Diss., 2010. http://hdl.handle.net/10500/4905.

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The axiomatic theory of ` Zelazko defines a variety of general spectra where specified axioms are satisfied. However, there arise a number of spectra, usually defined for a single element of a Banach algebra, that are not covered by the axiomatic theory of ` Zelazko. V. Kordula and V. M¨uller addressed this issue and created the theory of regularities. Their unique idea was to describe the underlying set of elements on which the spectrum is defined. The axioms of a regularity provide important consequences. We prove that the set of Koliha-Drazin invertible elements, which includes the Drazin invertible elements, forms a regularity. The properties of the spectrum corresponding to a regularity are also investigated.
Mathematical Sciences
M. Sc. (Mathematics)
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44

McCanna, David. "Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products." Thesis, 2009. http://hdl.handle.net/10012/4338.

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The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty associated with dose selection for clinical trials. The first section of this thesis describes how in vitro methods can be used to improve the prediction of the toxicity of chemicals and ophthalmic products. The proper utilization of in vitro methods can accurately predict toxic threshold levels and reduce animal use in product development. Sections two, three and four describe the development of new sensitive in vitro methods for predicting ocular toxicity. Maintaining the barrier function of the cornea is critical for the prevention of the penetration of infections microorganisms and irritating chemicals into the eye. Chapter 2 describes the development of a method for assessing the effects of chemicals on tight junctions using a human corneal epithelial and canine kidney epithelial cell line. In Chapter 3 a method that uses a primary organ culture for assessing single instillation and multiple instillation toxic effects is described. The ScanTox system was shown to be an ideal system to monitor the toxic effects over time as multiple readings can be taken of treated bovine lenses using the nondestructive method of assessing for the lens optical quality. Confirmations of toxic effects were made with the utilization of the viability dye alamarBlue. Chapter 4 describes the development of sensitive in vitro assays for detecting ocular toxicity by measuring the effects of chemicals on the mitochondrial integrity of bovine cornea, bovine lens epithelium and corneal epithelial cells, using fluorescent dyes. The goal of this research was to develop an in vitro test battery that can be used to accurately predict the ocular toxicity of new chemicals and ophthalmic formulations. By comparing the toxicity seen in vivo animals and humans with the toxicity response in these new in vitro methods, it was demonstrated that these in vitro methods can be utilized in a tiered testing strategy in the development of new chemicals and ophthalmic formulations.
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