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Journal articles on the topic 'LBA_HB'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Sawsan, Rabaya, and Al Moayed Yazeed. "Comparative Analysis of Load Balancing Algorithms for Efficient Task Scheduling in Cloud Computing." International Journal of Computer Science and Information Technology Research 11, no. 3 (2023): 160–71. https://doi.org/10.5281/zenodo.8355059.

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<strong>Abstract:</strong> In the field of information technology cloud computing is a recently developed technology. In such a complicated system, an effective load balancing scheme is critical in order to meet peak user demands and deliver high-quality services. Load balancing is a way of distributing workload among several nodes over network links in order to maximize resource utilization, decrease data processing and response time, and avoid overload. There have been a number of load balancing algorithms suggested that concentrate on important factors including processing time, response ti

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2

Hermann, Johannes, Phillip Nowotny, Tobias E. Schrader, Philipp Biggel, Dariusch Hekmat, and Dirk Weuster-Botz. "Neutron and X-ray crystal structures of Lactobacillus brevis alcohol dehydrogenase reveal new insights into hydrogen-bonding pathways." Acta Crystallographica Section F Structural Biology Communications 74, no. 12 (2018): 754–64. http://dx.doi.org/10.1107/s2053230x18015273.

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Lactobacillus brevis alcohol dehydrogenase (LbADH) is a well studied homotetrameric enzyme which catalyzes the enantioselective reduction of prochiral ketones to the corresponding secondary alcohols. LbADH is stable and enzymatically active at elevated temperatures and accepts a broad range of substrates, making it a valuable tool in industrial biocatalysis. Here, the expression, purification and crystallization of LbADH to generate large, single crystals with a volume of up to 1 mm3 suitable for neutron diffraction studies are described. Neutron diffraction data were collected from an H/D-exc

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3

Stepanov, Konstantin, Dmitry Mukhin, and Olga Volkova. "Experimental investigation of a plate heat exchanger model for lithium bromide absorption chillers: first results." EPJ Web of Conferences 196 (2019): 00033. http://dx.doi.org/10.1051/epjconf/201919600033.

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In this paper the results of thermal-hydraulic tests of a sample of a perspective plate heat exchanger under the conditions of LBAHT is described. Working opportunity of the sample working under conditions of LBAHT has been confirmed by this research.

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4

Walla, Brigitte, Daniel Bischoff, Robert Janowski, Nikolas von den Eichen, Dierk Niessing, and Dirk Weuster-Botz. "Transfer of a Rational Crystal Contact Engineering Strategy between Diverse Alcohol Dehydrogenases." Crystals 11, no. 8 (2021): 975. http://dx.doi.org/10.3390/cryst11080975.

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Protein crystallization can serve as a purification step in biotechnological processes but is often limited by the non-crystallizability of proteins. Enabling or improving crystallization is mostly achieved by high-throughput screening of crystallization conditions and, more recently, by rational crystal contact engineering. Two selected rational crystal contact mutations, Q126K and T102E, were transferred from the alcohol dehydrogenases of Lactobacillus brevis (LbADH) to Lactobacillus kefir (LkADH). Proteins were expressed in E. coli and batch protein crystallization was performed in stirred

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5

Peschke, Theo, Patrick Bitterwolf, Silla Hansen, Jannis Gasmi, Kersten Rabe, and Christof Niemeyer. "Self-Immobilizing Biocatalysts Maximize Space–Time Yields in Flow Reactors." Catalysts 9, no. 2 (2019): 164. http://dx.doi.org/10.3390/catal9020164.

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Maximizing space–time yields (STY) of biocatalytic flow processes is essential for the establishment of a circular biobased economy. We present a comparative study in which different biocatalytic flow reactor concepts were tested with the same enzyme, the (R)-selective alcohol dehydrogenase from Lactobacillus brevis (LbADH), that was used for stereoselective reduction of 5-nitrononane-2,8-dione. The LbADH contained a genetically encoded streptavidin (STV)-binding peptide to enable self-immobilization on STV-coated surfaces. The purified enzyme was immobilized by physisorption or chemisorption

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6

Delacroix, Sinny, Brian J. Boylan, Adriana Harbuzariu, et al. "NPR-B Expression In Megakaryocytes and Platelets." Blood 116, no. 21 (2010): 4319. http://dx.doi.org/10.1182/blood.v116.21.4319.4319.

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Abstract Abstract 4319 C-type natriuretic peptide (CNP) is known to exert pleiotropic effects on a variety of cell types through binding to its receptor, natriuretic peptide receptor type B (NPR-B) and activation of the cytoplasmic intracellular guanylyl cyclase domain. Although nitric oxide-mediated activation of cyclic guanosine monophosphate (cGMP) is known to induce megakaryocyte apoptosis and regulate platelet activation, the effects of CNP on these cells is yet to be defined. In this study for the first time we have addressed the potential role of CNP and NPR-B in megakaryocyte and plate

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7

Mentges, Julian, Daniel Bischoff, Brigitte Walla, and Dirk Weuster-Botz. "In Situ Microscopy with Real-Time Image Analysis Enables Online Monitoring of Technical Protein Crystallization Kinetics in Stirred Crystallizers." Crystals 14, no. 12 (2024): 1009. http://dx.doi.org/10.3390/cryst14121009.

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Controlling protein crystallization processes is essential for improving downstream processing in biotechnology. This study investigates the combination of machine learning-based image analysis and in situ microscopy for real-time monitoring of protein crystallization kinetics. The experimental research is focused on the batch crystallization of an alcohol dehydrogenase from Lactobacillus brevis (LbADH) and two selected rational crystal contact mutants. Technical protein crystallization experiments were performed in a 1 L stirred crystallizer by adding polyethyleneglycol 550 monomethyl ether (

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8

Kondo, Eri, Akihiro Yasoda, Takehito Tsuji, et al. "Skeletal Analysis of the Long Bone Abnormality (lbab/lbab) Mouse, A Novel Chondrodysplastic C-Type Natriuretic Peptide Mutant." Calcified Tissue International 90, no. 4 (2012): 307–18. http://dx.doi.org/10.1007/s00223-011-9567-0.

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9

Walla, Brigitte, Anna Maslakova, Daniel Bischoff, Robert Janowski, Dierk Niessing, and Dirk Weuster-Botz. "Rational Introduction of Electrostatic Interactions at Crystal Contacts to Enhance Protein Crystallization of an Ene Reductase." Biomolecules 15, no. 4 (2025): 467. https://doi.org/10.3390/biom15040467.

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Protein crystallization is an alternative to well-established but cost-intensive and time-consuming chromatography in biotechnological processes, with protein crystallization defined as an essential unit operation for isolating proteins, e.g., active pharmaceutical ingredients. Crystalline therapeutic proteins attract interest in formulation and delivery processes of biopharmaceuticals due to the high purity, concentration, and stability of the crystalline state. Although improving protein crystallization is mainly achieved by high-throughput screening of crystallization conditions, recent stu

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10

Stepanov, K. I., and D. G. Mukhin. "Energy efficiency of an absorption thermotransformer with two-stage absorption as part of a heat and cold supply complex based on a gas boiler house." Journal of Physics: Conference Series 2119, no. 1 (2021): 012105. http://dx.doi.org/10.1088/1742-6596/2119/1/012105.

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Abstract The article proposes a scheme for using a lithium bromide absorption thermotransformer (LBATT) with two-stage absorption for deep utilization of the heat of combustion products (CPs) of gas boilers. At the same time, this solution allows heating the dictrict heating systems return water in the cold season. In the warm season, LBATT is used to cool the water of the air conditioning system or process equipment cooling. In this case, heat removal from LBAHT with two-stage absorption in the warm season is carried out using an drycooler. The analysis of the effectiveness of the use of LBAT

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11

Ng, Jeck Fei, and Stephan Jaenicke. "Immobilized Whole Cells as Effective Catalysts for Chiral Alcohol Production." Australian Journal of Chemistry 62, no. 9 (2009): 1034. http://dx.doi.org/10.1071/ch09112.

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Recombinant Escherichia coli overexpressing the gene LbADH, which encodes for an alcohol dehydrogenase from Lactobacillus brevis, was successfully transformed and cultured. The cells are able to catalyze the reduction of pro-chiral ketones, e.g. ethyl acetoacetate into R-(–)ethyl hydroxybutyrate (EHB) with high conversion and enantiomeric excess >99%. Immobilizing the whole cells in alginate beads leads to a catalyst with improved stability and ease of handling while maintaining the high activity of the free cells. The whole-cell catalyst was tested in a stirred batch reactor (CSTR) and in

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12

Merinas-Amo, Tania, Rocío Merinas-Amo, Rafael Font, Mercedes del Río Celestino, and Ángeles Alonso-Moraga. "Toxicological and Epigenetic Studies of Two Types of Ale Beer, Tyrosol and Iso-Alpha Humulone." Processes 9, no. 3 (2021): 485. http://dx.doi.org/10.3390/pr9030485.

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Although many benefits drawn from beer consumption are claimed, the epidemiological records are contradictory with respect to cancer prevention. The purpose of this study was to investigate the possible health-related activities involving genome safety and the ageing processes of two types of lyophilised ale beers (blond and stout), as well as two of their bioactive compounds (tyrosol and iso-alpha humulone). A multipurpose trial set of in vivo toxicity, antitoxicity, mutagenicity, antimutagenicity, lifespan and healthspan assays using Drosophila melanogaster were used. In parallel, several in

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13

Döbber, J., M. Pohl, S. V. Ley, and B. Musio. "Rapid, selective and stable HaloTag-LbADH immobilization directly from crude cell extract for the continuous biocatalytic production of chiral alcohols and epoxides." Reaction Chemistry & Engineering 3, no. 1 (2018): 8–12. http://dx.doi.org/10.1039/c7re00173h.

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14

Jiao, Yan, Jian Yan, Feng Jiao, et al. "A single nucleotide mutation in Nppc is associated with a long bone abnormality in lbab mice." BMC Genetics 8, no. 1 (2007): 16. http://dx.doi.org/10.1186/1471-2156-8-16.

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15

Hermann, Johannes, Daniel Bischoff, Phillip Grob, et al. "Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts." Crystals 11, no. 6 (2021): 588. http://dx.doi.org/10.3390/cryst11060588.

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Protein crystallization can function as an effective method for protein purification or formulation. Such an application requires a comprehensive understanding of the intermolecular protein–protein interactions that drive and stabilize protein crystal formation to ensure a reproducible process. Using alcohol dehydrogenase from Lactobacillus brevis (LbADH) as a model system, we probed in our combined experimental and computational study the effect of residue substitutions at the protein crystal contacts on the crystallizability and the contact stability. Increased or decreased contact stability

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16

Yoder, Andrea R., Andrew C. Kruse, Cathleen A. Earhart, Douglas H. Ohlendorf, and Lincoln R. Potter. "Reduced ability of C-type natriuretic peptide (CNP) to activate natriuretic peptide receptor B (NPR-B) causes dwarfism in lbab−/− mice." Peptides 29, no. 9 (2008): 1575–81. http://dx.doi.org/10.1016/j.peptides.2008.04.020.

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17

AMIN, SUHCROTUL. "INOVASI PENDIDIKAN ISLAM PERSPEKTIF ORANG TUA DALAM PENERAPAN MANAJEMEN MUTU TERPADU DI SDIT CENDIKIA." TEACHING : Jurnal Inovasi Keguruan dan Ilmu Pendidikan 2, no. 4 (2023): 453–62. http://dx.doi.org/10.51878/teaching.v2i4.1881.

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In the era before 2000 the institutionof Islamic education was underestimated. Islamic institutions at that time were only considered alternative schools if they were not accepted into the favorite state education institutions. However, at this time the Islamic education institutions have been able to carry out amazing innovations, not even a few Islamic education institutions have appeared to be superior and quality institutions. One of the factors for the realization of this is due to the implementation of Integrated Quality Management in islamic institutions. Therefore, this research is imp

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18

"Hybrid Load Balancing Approach based on the Integration of QoS and Power Consumption in Cloud Computing." International Journal of Advanced Trends in Computer Science and Engineering 10, no. 2 (2021): 1079–90. http://dx.doi.org/10.30534/ijatcse/2021/841022021.

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Over the past few years, there has been keen research interest in load balancing and task scheduling in the cloud as the extensive amount of data that is stored in the server leads to significantly increased load. This can be resolved by using a hybrid algorithm in which the honeybee behavior algorithm’s advantages are integrated with fuzzy logic to conduct task scheduling and as well as balancing in the cloud. The design of this hybrid algorithm aims to enhance prior approaches. It is developed as per ABC and merges the important QoS factors along with power consumption so that the power that

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19

Su, Guorong, Lu Ran, Chang Liu, Zhaoyang Qin, Huailong Teng, and Shuke Wu. "Directed Evolution and Immobilization of Lactobacillus brevis Alcohol Dehydrogenase for Chemo‐enzymatic Synthesis of Rivastigmine." Chemistry – A European Journal, April 3, 2024. http://dx.doi.org/10.1002/chem.202400454.

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Rivastigmine is one of the several pharmaceuticals widely prescribed for the treatment of Alzheimer's disease. However, its practical synthesis still faces many issues, such as the involvement of toxic metals and harsh reaction conditions. Herein, we report a chemo‐enzymatic synthesis of Rivastigmine. The key chiral intermediate was synthesized by an engineered alcohol dehydrogenase from Lactobacillus brevis (LbADH). A semi‐rational approach was employed to improve its catalytic activity and thermal stability. Several LbADH variants were obtained with a remarkable increase in activity and melt

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