Academic literature on the topic 'LC-MS (Liquid Chromatography-Mass Spectrometry)'

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Journal articles on the topic "LC-MS (Liquid Chromatography-Mass Spectrometry)"

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Archita, Tiwari, Dubey Vishwanath, Mishra Shilpi, et al. "General Instrumentation of LC-MS Technique and their Recent Applications." International Journal of Innovative Science and Research Technology 7, no. 5 (2022): 1469–73. https://doi.org/10.5281/zenodo.6760060.

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This review summarizes the advancement in liquid chromatography-mass spectrometry (LC-MS). Liquid Chromatography and Mass Spectrometer is a hyphenated technique of separation of compounds. over the past years, the combination 0f high-performance liquid chromatography and mass spectrometry (LC-MS) has been used which has a remarkable effect on drug research and development. LC-MS played a vital role in the assessment and interpretation of bioavailability and bioequivalence. This article reviews the principle of LCMS analysis using liquid chromatography and mass spectrometry. Mass spectrometry c
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Radović, Radmila, Bojana Radić, Sanja Đekić, Sanja Belić, and Jovana Kos. "State-of-the-art mycotoxin analysis: Insights from LC/MS-MS method." Food and Feed Research, no. 00 (2025): 73. https://doi.org/10.5937/ffr0-55401.

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Mycotoxins are secondary metabolites produced by fungi, known for their chemical and thermal stability, which makes them resistant to common food and feed processing methods. These toxins can contaminate food and feed, and cause a range of toxic effects upon ingestion, including mutagenic, teratogenic, carcinogenic, immunotoxic, neurotoxic, hepatotoxic, and dermatotoxic effects. In recent years, the application of liquid chromatography combined with tandem mass spectrometry has grown significantly for mycotoxin analysis, owing to its remarkable sensitivity and specificity. Recent literature hi
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Gelb, Michael H., Khaja Basheeruddin, Alberto Burlina, et al. "Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories." International Journal of Neonatal Screening 8, no. 4 (2022): 62. http://dx.doi.org/10.3390/ijns8040062.

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Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS). Among the MS/MS applications in NBS, the most common is flow-injection analysis (FIA-) MS/MS, where the sample is introduced as a bolus injection into the mass spectrometer without the prior fractionation of analytes. Liquid chromatography combined with MS/MS (LC-MS/MS) has been employed for second-tier tests to reduce the false-positive rate associated with several nonspecific screeni
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M Pavan Kumar, A Naga Akshay Kumar, D Pooja, M Ahalya, SK Mastan Vali, and Y Yamini. "A comprehensive study on sitagliptin in the treatment of Type-II Diabetes." World Journal of Biology Pharmacy and Health Sciences 20, no. 3 (2024): 120–29. https://doi.org/10.30574/wjbphs.2024.20.3.0988.

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Sitagliptin is an oral antihyperglycemic drug classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor; commonly used in the treatment of type 2 diabetes. It works by promoting insulin secretion and decreasing glucagon levels through the inhibition of incretin degradation in a glucose-dependent manner. As of 2013; it was the second-highest selling medication in the United States. This review highlights various analytical techniques for the quantification of sitagliptin; either alone or in combination with other agents. These methods include spectrometry; high-performance liquid chromatography
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Alder, Lutz, James R. Startin, S. Alonso, et al. "Determination of Chlormequat and Mepiquat in Foods by Liquid Chromatography/Mass Spectrometry or Liquid Chromatography/Tandem Mass Spectrometry: Interlaboratory Study." Journal of AOAC INTERNATIONAL 88, no. 6 (2005): 1762–76. http://dx.doi.org/10.1093/jaoac/88.6.1762.

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Abstract Interlaboratory validation studies have been performed on 2 methods for the determination of chlormequat (CLQ) and mepiquat (MPQ). Both methods used identical extraction procedures and stable isotope internal standardization but differed in the use of liquid chromatography/mass spectrometry (LC/MS) or LC/tandem mass spectrometry (LC/MS/MS) for the determination, the amount of internal standard used, and the expected limit of detection. After addition of deuterated internal standards, CLQ and MPQ were extracted with methanol–water and determined by LC/MS or LC/MS/MS with positive elect
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Pisitkun, Trairak, Jason D. Hoffert, Ming-Jiun Yu, and Mark A. Knepper. "Tandem Mass Spectrometry in Physiology." Physiology 22, no. 6 (2007): 390–400. http://dx.doi.org/10.1152/physiol.00025.2007.

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Tandem mass spectrometry coupled to liquid chromatography (LC-MS/MS) allows identification of proteins in a complex mixture without need for protein purification (“shotgun” proteomics). Recent progress in LC-MS/MS-based quantification, phosphoproteomic analysis, and targeted LC-MS/MS using multiple reaction monitoring (MRM) has made LC-MS/MS a powerful tool for the study of cell physiology.
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Prasad, B. Satya. "AN ANALYTICAL REVIEW-BASED STUDY ON SITAGLIPTIN." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 07, no. 10 (2023): 1–11. http://dx.doi.org/10.55041/ijsrem25947.

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Sitagliptin is an oral anti-hyperglycemic agent of the dipeptidyl peptidase-4 (DPP-4) inhibitor magnificence used inside the remedy of type-2 diabetes. It stimulates insulin release and reduces glucagon levels by inhibiting of inactivation of the incretin in a glucose-dependent manner. In 2013 it was the second best- selling drug in the U.S. This evaluation encompasses diverse analytical strategies inclusive of spectrometry, high-overall performance liquid chromatography (HPLC), liquid chromatography-electrospray ionization- mass spectrometry (LC-ESI-MS-MS), liquid chromatography-mass spectrom
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Shounak, Mande*. "A Review Article on Hyphenated Techniques Used in Analytical Method and Development." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 2407–17. https://doi.org/10.5281/zenodo.14762916.

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The hyphenated techniques refers to the combination or synthesis of distinct analytical methodologies. Spectroscopic techniques are mostly paired with chromatographic techniques. After that, an interphase will allow the mixture's separated components from the chromatographic approach to enter the spectroscopic technique. In GC-MS After separation from gas chromatography, ionization and mass spectrometry are added to MS. analysis and measurement of the mass-to-charge ratios of the ions that the mass spectrometer generates from each analysis. GC and MS can be connected by a membrane separator, j
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Vanitha Madhuri T, Santhosh Kumar Sorapalli, Kishore Babu Kagitha, et al. "A Review of Liquid Chromatography-Mass Spectrometry and its Applications in Chemical Analysis." Journal of Pharma Insights and Research 2, no. 6 (2024): 025–32. https://doi.org/10.69613/gre1zt18.

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Liquid Chromatography-Mass Spectrometry (LC-MS) has emerged as a powerful analytical technique combining the separation capabilities of liquid chromatography with the high sensitivity and selectivity of mass spectrometry. This sophisticated instrumentation enables precise identification and quantification of complex chemical mixtures across diverse fields including pharmaceuticals, environmental monitoring, food safety, and biological research. Modern LC-MS systems offer enhanced resolution, improved ionization methods, and sophisticated mass analyzers that facilitate accurate molecular weight
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Patel, Nirali G., D. A. Dhale, and Mayuri C. Rathod. "Analysis of Pesticide Residue in Fruit Using the QuEChERS Method Coupled With LC-MS/MS Detection." Current Agriculture Research Journal 12, no. 2 (2024): 865–72. http://dx.doi.org/10.12944/carj.12.2.29.

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Identifying pesticide residues in fruits is essential to both regulatory compliance and food safety. For this use, liquid chromatography combined with tandem mass spectrometry, or liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS), is an advanced analytical method that provides excellent sensitivity and specificity. This work offers a thorough procedure for employing LC-MS/MS to extract, clean up, and quantify various pesticide residues in fruit samples.The QuEChERS technique, which uses acetonitrile and a salting-out step for effective partitioning, first homogenizes the fru
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Dissertations / Theses on the topic "LC-MS (Liquid Chromatography-Mass Spectrometry)"

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Crnogorac, Goranka. "Analysis of dithiocarbamate fungicide residues by liquid chromatography, mass spectrometry and isotope ratio mass spectrometry." Aachen Shaker, 2008. http://d-nb.info/993691447/04.

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Törnvall, Erica. "Determination of testosterone esters in serum by liquid chromatography – tandem mass spectrometry (LC-MS-MS)." Thesis, Linköping University, Organic Analytical Chemistry, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-58045.

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<p>Anabolic androgenic steroids are testosterone and its derivates. Testosterone is the most important naturally existing sex hormone for men and is used for its anabolic effects providing increased muscle mass. Testosterone is taken orally or by intramuscular injection in its ester form and are available illegally in different forms of esters. Anabolic androgenic steroids are today analyzed only in urine. To differentiate between the human natural testosterone and exogenous supply the quote natural testosterone and epitestosterone is used. Detection of testosterone esters in serum is an unmis
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Cerruti, Laura F. "Evaluation of a particle beam interface for LC/MS." Thesis, Virginia Tech, 1989. http://hdl.handle.net/10919/44624.

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<p>The performance of a Hewlett Packard Particle Beam LC/MS interface is evaluated using EPA appendix VIII and IX compounds. The behavior of these priority pollutants in the interface could determine its feasibility as a future EPA certified technique.</p> <p>The evaluation process consists of studies to determine minimum detectable quantities (MDQ), linear response, and band broadening contributions. The MDQ's of the analytes in electron impact and chemical ionization modes are extrapolated from experimental signal to noise data. The linearity study involves ten compounds analyzed
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Nicolaou, Anna, Mojgan Masoodi, and Adnan A. Mir. "Lipidomic analysis of prostanoids by liquid chromatography-electrospray tandem mass spectrometry." Springer, 2009. http://hdl.handle.net/10454/4575.

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no<br>Lipidomics aim to generate qualitative and quantitative information on different classes of lipids and their species, and when applied in conjunction with proteomic and genomic assays, facilitate the comprehensive study of lipid metabolism in cellular, organ or body systems. Advances in mass spectrometry have underpinned the expansion of lipidomic methodologies. Prostanoids are potent autacoids present in a plethora of cellular systems, known best for their intimate role in inflammation. Electrospray ionisation (ESI) allows the efficient ionisation of prostanoids in aqueous systems. ESI
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Nascimento, DemÃtrius Fernandes do. "Nimodipine determination in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS-MS)." Universidade Federal do CearÃ, 2005. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=31.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>A rapid, specific and highly sensitive liquid chromatography-tandem mass spectrometry method was developed to determine nimodipine in human plasma using dibucaine as the internal standard (IS) is described. The analyte (m/z 418,6 > 342,6) and IS (m/z 344,2 > 271,0) were extracted from plasma samples by liquid-liquid extraction using hexane-ethyl acetate (1:1v/v). Chromatography was performed on a Varian Polaris C18 analytical column (3 micrometer, 50 x 2,0 mm) and pre-column SecurityguardTM C18 (4,0 x 3,0 mm). The phase mobile c
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Rousu, T. (Timo). "Liquid chromatography–mass spectrometry in drug metabolism studies." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789514298172.

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Abstract Drug metabolite profiling and identification studies are nowadays regularly conducted with liquid chromatography (LC) coupled with mass spectrometry (MS) as an analytical tool. The speed, selectivity and sensitivity of modern LC–MS instruments have been significantly increased in recent years. Especially the use of ultra-high-performance LC (UHPLC) in combination with a modern high-resolution MS instrument offers high full scan detection sensitivity, mass accuracy and the detection of both expected and unexpected metabolites in a single LC–MS run. The present study showed that no sing
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Zhou, Bin. "Computational Analysis of LC-MS/MS Data for Metabolite Identification." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/36109.

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Metabolomics aims at the detection and quantitation of metabolites within a biological system. As the most direct representation of phenotypic changes, metabolomics is an important component in system biology research. Recent development on high-resolution, high-accuracy mass spectrometers enables the simultaneous study of hundreds or even thousands of metabolites in one experiment. Liquid chromatography-mass spectrometry (LC-MS) is a commonly used instrument for metabolomic studies due to its high sensitivity and broad coverage of metabolome. However, the identification of metabolites remains
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Shi, Wunan. "High-Throughput De Novo Sequencing of Transfer RNAs Using Liquid Chromatography-Tandem Mass Spectrometry." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1378197247.

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Tarr, Matthew Aaron. "Characterization and optimization of sample introduction systems for ICP-AES, ICP-MS, and LC-MS." Diss., Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/27987.

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Allegood, Jeremy Chadwick. "Application of liquid chromatography tandem mass spectrometry for the separation and quantitative analysis of sphingolipids." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/42691.

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Sphingolipids are a highly diverse category of compounds that serve not only as components of biologic structures but also as regulators of numerous cell functions. Because so many of the structural features of sphingolipids influence their biological activity, there is a need for comprehensive methods for quantitation of as many individual subspecies as possible. This dissertation describes methods that have been developed and validated for the extraction, liquid chromatographic separation, identification and quantitation of sphingolipids by electrospray ionization (ESI), tandem mass spectr
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Books on the topic "LC-MS (Liquid Chromatography-Mass Spectrometry)"

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McMaster, Marvin. LC/MS. John Wiley & Sons, Ltd., 2005.

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Ferrer, Imma, and E. M. Thurman, eds. Liquid Chromatography/Mass Spectrometry, MS/MS and Time of Flight MS. American Chemical Society, 2003. http://dx.doi.org/10.1021/bk-2003-0850.

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Cremin, Peter A. A phytochemical investigation and liquid chromatography-mass spectrometry (LC-MS) analysis of eight Armillaria species. University College Dublin, 1996.

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Oehme, Michael. Pratical introduction to GC-MS analysis with quadrupoles. Edited by Dünges Wolfgang. Heidelberg, 1999.

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1970-, Ferrer Imma, Thurman E. M. 1946-, American Chemical Society. Division of Environmental Chemistry., and American Chemical Society Meeting, eds. Liquid chromatography/mass spectrometry, MS/MS and time of flight MS: Analysis of emerging contaminants. American Chemical Society, 2003.

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Yancey, M. F. Capillary column GC-MS determination of 77 purgeable organic compounds in two simulated liquid wastes. U.S. Environmental Protection Agency, Environmental Monitoring and Support Laboratory, 1988.

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Yancey, M. F. Capillary column GC-MS determination of 77 purgeable organic compounds in two simulated liquid wastes. U.S. Environmental Protection Agency, Environmental Monitoring and Support Laboratory, 1988.

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Yancey, M. F. Capillary column GC-MS determination of 77 purgeable organic compounds in two simulated liquid wastes. U.S. Environmental Protection Agency, Environmental Monitoring and Support Laboratory, 1988.

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Yancey, M. F. Capillary column GC-MS determination of 77 purgeable organic compounds in two simulated liquid wastes. U.S. Environmental Protection Agency, Environmental Monitoring and Support Laboratory, 1988.

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Yancey, M. F. Capillary column GC-MS determination of 77 purgeable organic compounds in two simulated liquid wastes. U.S. Environmental Protection Agency, Environmental Monitoring and Support Laboratory, 1988.

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Book chapters on the topic "LC-MS (Liquid Chromatography-Mass Spectrometry)"

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Yergey, Alfred L., Charles G. Edmonds, Ivor A. S. Lewis, and Marvin L. Vestal. "LC/MS of Conjugated Molecules." In Liquid Chromatography/Mass Spectrometry. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4899-3605-9_7.

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Yergey, Alfred L., Charles G. Edmonds, Ivor A. S. Lewis, and Marvin L. Vestal. "LC/MS of Nucleic Acid Constituents." In Liquid Chromatography/Mass Spectrometry. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4899-3605-9_6.

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Munjanja, Basil K. "Liquid Chromatography Mass Spectrometry (LC-MS)." In Multiresidue Methods for the Analysis of Pesticide Residues in Food. CRC Press, 2017. http://dx.doi.org/10.1201/9781315118352-7.

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Yergey, Alfred L., Charles G. Edmonds, Ivor A. S. Lewis, and Marvin L. Vestal. "Applications of LC/MS to Amino Acids, Peptides, and Proteins." In Liquid Chromatography/Mass Spectrometry. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4899-3605-9_8.

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Thurman, E. Michael, Imma Ferrer, Jerry A. Zweigenbaum, and Paul A. Zavitsanos. "Comparison Of LC/TOF-MS and LC/MS-MS for the Analysis of 100 Pesticides in Food: Finding the “Crossover Point”." In Liquid Chromatography Time-of-Flight Mass Spectrometry. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470429969.ch14.

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Jian, Wenying. "Modern Liquid Chromatography and Mass Spectrometry for Targeted Biomarker Quantitation." In Targeted Biomarker Quantitation by LC-MS. John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119413073.ch4.

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Salamatipour, Ashkan, Ian A. Blair, and Clementina Mesaros. "Targeted Lipid Biomarker Quantitation Using Liquid Chromatography-Mass Spectrometry (LC-MS)." In Targeted Biomarker Quantitation by LC-MS. John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119413073.ch17.

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Ojanperä, Ilkka, Anna Pelander, and Suvi Ojanperä. "Comprehensive Toxicological and Forensic Drug Screening by LC/TOF-MS." In Liquid Chromatography Time-of-Flight Mass Spectrometry. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470429969.ch11.

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Arpino, P. J. "Combined Liquid Chromatography/Mass Spectrometry (LC/MS): A Review." In Mass Spectrometry in the Biological Sciences: A Tutorial. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2618-2_14.

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Henry, Michael, and Paula Meleady. "Clinical Proteomics: Liquid Chromatography–Mass Spectrometry (LC–MS) Purification Systems." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6412-3_20.

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Conference papers on the topic "LC-MS (Liquid Chromatography-Mass Spectrometry)"

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Devina, Kezia Elian, Dono Indarto, and Tri Nugraha Susilawati. "Identification of Quercetin and Chrysin in Banana Peel Extract Using High Performance Liquid Chromatography and Liquid Chromatography Mass Spectrometer for Obesity Treatment." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-6iz2xi.

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Pancreatic lipase plays an important role in converting triglyceride into long-chain fatty acids and glycerol, then becomes a therapeutic target for obesity treatment. Quercetin and chrysin are able to inhibit pancreatic lipase, which is potentially developed for obesity treatment. This study aimed to identify quercetin and chrysin derived from the methanol extract of raja and kepok banana peels using High Performance Liquid Chromatography (HPLC) and Liquid Chromatography Mass Spectrometer (LC-MS) for the development of obesity treatment. Raja and kepok banana peels were purchased from a fruit
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Jackson, Tracey, and Jonathan Vargas. "Selective Loss of Bulk Corrosion Inhibitor Species When Exposed to Glass, Plastic, and Steel." In CORROSION 2020. NACE International, 2020. https://doi.org/10.5006/c2020-14999.

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Abstract Despite the widespread use of corrosion inhibitors (CIs) in the oil and gas industry much of their complex aggregation and adsorption behavior is still very poorly understood. CIs are surface active species meaning that when they are injected into aqueous solutions they naturally aggregate and migrate to gas-liquid, liquid-liquid, and solid-liquid interfaces. A better understanding of each CI component and how it adsorbs when exposed to various surfaces could lead to improved CI design, higher performance at lower dosages, as well as improved methods for residual detection. This paper
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Jenkins, Alyn, Ian Gilbert, Aiman Kamaruzaman, and Astrid Lone. "Top-of-Line Corrosion Inhibition and Proposal of an Inhibition Mechanism." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-11117.

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Abstract Multiphase pipelines manufactured from carbon steel are susceptible to several forms of corrosion, including top-of-line (TOL) corrosion. In wet gas pipelines, produced water can condense at the top of the pipeline when the temperature and pressure along the length of the pipeline decreases. If this happens, TOL corrosion will occur, which can be severe as the pH of the condensed water will be very low (&amp;lt; 5). However, it is possible to mitigate TOL corrosion with the application of corrosion inhibitors. Using corrosion inhibitors to control TOL corrosion in multiphase systems p
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Barker, Richard, Richard C. Woollam, and William H. Durnie. "Implications of Physical and Chemical Environment on the Distribution of Corrosion Inhibitor Surfactant Components and Mixtures." In CONFERENCE 2025. AMPP, 2025. https://doi.org/10.5006/c2025-00436.

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Abstract Corrosion inhibitors are a proven cost-effective method for internal corrosion protection of carbon steel piping in the presence of CO2-containing brines. The appropriate selection, deployment and performance monitoring are all essential elements ensuring successful application. However, despite many years of use within the oil and gas industry, a clear understanding of the impact of the physical chemistry of surfactants and surfactant mixtures still eludes the industry, and chemical law is often replaced with oilfield lore. In this work, the effect of brine salinity (0.1, 1 and 10 wt
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Ferrer, Ana, Yolanda De-Abreu, and Carol Roach. "Evaluating the Impact of Different Families of Scale Inhibitors on Corrosion Inhibitor Performance by Surface Tension and Electrochemical Impedance Spectroscopy Measurements." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-11505.

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Abstract It is well known that chemical interactions between scale inhibitor (SI) and corrosion inhibitor (CI) might lead to a reduction in the performance efficiency of both chemicals. Scale and corrosion inhibitors are widely used in the oil and gas industry; thus it is very important to understand how they impact each other's performance. This paper attempted to explain how different families of scale inhibitors impact corrosion inhibitors performance in the presence of each other. For this purpose, this paper addressed fundamental properties of both chemistries and how their interaction ca
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Bykov, Alexey, Galina Demidenko, Linda Nikoshvili, and Elena Bakhvalova. "INFLUENCE OF THE NATURE OF AROMATIC POLYMER AS A PT PARTICLE STABILIZER ON ITS ACTIVITY AND SELECTIVITY IN THE LIQUID-PHASE HYDROGENATION OF AROMATIC AND POLYAROMATIC SUBSTRATES." In 24th SGEM International Multidisciplinary Scientific GeoConference 24. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024/4.1/s17.16.

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A series of platinum catalytic systems stabilized in aromatic polymers were obtained in this work. Commercially available styrene-divinylbenzene (MN100) and polymers synthesized by one-stage crosslinking by the Friedel-Crafts reaction from benzene, naphthalene, and an equimolar benzene-naphthalene mixture were used as polymers. The obtained systems were tested in liquid-phase hydrogenation reactions of benzene, toluene, and benzene-toluene mixture, as well as anthracene in a dodecane medium. The reaction products were studied using GC-MS. Polymers and catalytic systems were studied using diffu
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Wahono, Jessica Zivanni, Harianingsih, Miranda Talitha Z., and Nelson Saksono. "Liquid chromatography mass spectrometry (LC-MS) of phenol degradation using plasma electrolysis method." In 3RD INTERNATIONAL CONFERENCE ON CHEMISTRY, CHEMICAL PROCESS AND ENGINEERING (IC3PE). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0062197.

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Byrdwell, William, and Hari Kiran Kotapati. "Adventures in multiple dimensions of chromatography and mass spectrometry for lipidomic analysis." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/athx8798.

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Two-dimensional liquid chromatography (2D-LC) is commercially available and has become increasingly common in laboratories across the world. Most 2D-LC systems that are coupled to mass spectrometry use one mass spectrometer attached to the outlet of the second dimension, and the first dimension is reconstructed by “stitching together” the signal from all of the modulation periods. This requires short, fast separations in the second dimension, and fast-scanning mass spectrometers, otherwise “under sampling” can occur. Quantification is problematic using the “blobs” in 2D-LC chromatograms. We ha
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McGrath, Thomas, Adrian Covaci, Els Van Hoeck, et al. "Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-high resolution mass spectrometry (LC-HRMS) approaches for analysis of chlorinated paraffins in edible fats and oils." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/wycg9726.

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Chlorinated paraffins (CPs) are high production volume chemicals composed of complex mixtures of thousands of compounds that have been applied widely as flame retardants and plasticizers. CPs have demonstrated toxic and bioaccumulative properties, while evidence suggests dietary intake to constitute a major pathway for human exposure. This study reports on the optimization and validation of an analytical method for the quantification of short- and medium-chained CPs (SCCPs and MCCPs, respectively) using gas chromatography-mass spectrometry (GC-MS) in fats and oils, and the development of liqui
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Blebea, Nicoleta Mirela, and Simona Negreș. "METHODS FOR QUANTIFICATION OF THE MAIN CANNABINOIDS IN CBD OIL." In GEOLINKS Conference Proceedings. Saima Consult Ltd, 2021. http://dx.doi.org/10.32008/geolinks2021/b1/v3/13.

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Cannabidiol (CBD) is an alkaloid present in Cannabis sativa, together with tetrahydrocannabinol (THC) and more than 120 other substances belonging to a group of compounds named cannabinoids. Due to the continuous increased usage of CBD oils, it became necessary to be developed efficient methods for the identification of its compounds and especially for the characterization of the cannabinoids from the commercial specimens. Cannabinoids may be detected by many and different analytical methods, including immunoassays (EMIT®, Elisa, fluorescent polarization, radioimmunotest), techniques of flat c
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Reports on the topic "LC-MS (Liquid Chromatography-Mass Spectrometry)"

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Kimble, Ashley, Derek Muensterman, Liliana Cahuas, et al. Extraction and analysis of per- and polyfluoroalkyl Substances (PFAS) from Meals Ready-to-Eat (MRE) films using GC-MS and LC-MS/MS. Engineer Research and Development Center (U.S.), 2023. http://dx.doi.org/10.21079/11681/47114.

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This work was in response to the Defense Logistic Agency’s (DLA) Subsistence Network Broad Agency Announcement, BAA-0003-16 addressing 2019 NDAA Section 329 that states packaging materials used for Meals Ready-to-Eat (MRE) that contact food products must be free of per- and polyfluoroalkyl substances (PFAS). This was addressed by determining the presence or absence of PFAS on MREs by extraction followed by gas chromatography mass spectrometry (GC-MS) and liquid chromatography tandem mass spectrometry (LC-MS/MS). Any samples positive for PFAS were quantitated using LC triple quadrupole (QqQ) MS
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Browner, R. F. Fundamental studies with a monodisperse aerosol-based liquid chromatography/mass spectrometry interface (MAGIC-LC/MS). Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/6179424.

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Browner, R. Fundamental studies with a monodisperse aerosol-based liquid chromatography/mass spectrometry interface (MAGIC-LC/MS). Office of Scientific and Technical Information (OSTI), 1989. http://dx.doi.org/10.2172/6963245.

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ว่องธวัชชัย, เจนนุข, та พรชัย โรจน์สิทธิศักดิ์. ปริมาณฮอร์โมนเมสทาโนโลนตกค้างในปลานิลหลังจากการกินฮอร์โมนในระยะเวลาสั้น : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2013. https://doi.org/10.58837/chula.res.2013.84.

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ปลานิลเป็นสัตว์น้ำเศรษฐกิจที่มีการเลี้ยงแบบหนาแน่น ลักษณะการเลี้ยงเป็นปลาเนื้อเพศผู้ (Monosex male tilapia) โดยการเหนี่ยวนำลูกปลาให้เจริญเป็นเพศผู้ด้วยการให้ฮอร์โมนเพศผู้แก่ลูกปลาวัยอ่อน เนื่องจากปลานิลเพศผู้มีการเจริญเติบโตดีกว่าเพศเมียและการเลี้ยงปลานิลแบบเพศผู้เพศเดียวเหมาะสมต่อการจัดการเมสทาโนโลนเป็นฮอร์โมนเพศผู้สังเคราะห์ชนิดหนึ่งที่มีการใช้ผสมอาหารให้ลูกปลากินในช่วงอนุบาลเพื่อวัตถุประสงค์ในการเหนี่ยวนำลูกปลกให้เจริญเป็นเพศผู้การวิจัยนี้ ทำการศึกษาประสิทธิภาพของเมสทาโนโลนในการเหนี่ยวนำเพศหลังจากการให้ลูกปลานิลกินฮอร์โมนขนาด 80 มิลลิกรัมต่อกิโลกรัมอาหาร ติดต่อเป็นระยะเวลา 15 วัน ประเมินผลก
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ภัทรกุล, กนิษฐา, ไตรรักษ์ พิสิษฐ์กุล, นพดล แสงจันทร์ та Jacquet, Alain. การค้นหาวัคซีนแอนติเจนตัวใหม่ของโรคเลปโตสไปโรซิสโดยอาศัยโปรตีโอมิกส์ของโปรตีนบนผิวเซลล์. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2018. https://doi.org/10.58837/chula.res.2018.37.

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โรคเลปโตสไปโรซิสเป็นโรคที่มีการแพร่กระจายในหลายพื้นที่รวมทั้งประเทศไทย มีสาเหตุมาจากเชื้อเลปโตสไปราสายพันธุ์ก่อโรค ซึ่งพยาธิกำเนิดของโรคยังไม่ทราบชัดเจน โปรตีนบนผิวเซลล์เป็นส่วนแรกที่เชื้อสัมผัสกับเซลล์ของโฮสต์และสามารถกระตุ้นระบบภูมิคุ้มกัน จึงเป็นเป้าหมายสำคัญในการพัฒนาวัคซีน การหาโปรตีนบนผิวเซลล์ทั้งหมดจะเป็นข้อมูลสำคัญสำหรับการศึกษาพยาธิกำเนิด และการค้นหาวัคซีนตัวใหม่ งานวิจัยนี้มีจุดมุ่งหมายเพื่อจำแนกโปรตีนบนผิวเซลล์ทั้งหมดของเชื้อเลปโตสไปราสายพันธุ์ก่อโรค Leptospira interrogans serovar Pomona ในการศึกษานี้ใช้ 2 วิธี ในการคัดแยกโปรตีนบนผิวเซลล์ออกจากโปรตีนอื่น ได้แก่ วิธีการย่อยโปรตีนบนผิ
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Beasley-Green, Ashley. Reference Measurement Procedure for the Absolute Quantification of Albumin in Urine Using Isotope Dilution-Liquid Chromatography-Tandem Mass Spectrometry (ID-LC-MS/MS). National Institute of Standards and Technology, 2024. http://dx.doi.org/10.6028/nist.sp.1200-31.

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Beasley-Green, Ashley. Reference Measurement Procedure for the Absolute Quantification of Albumin in Urine Using Isotope Dilution-Liquid Chromatography-Tandem Mass Spectrometry (ID-LC-MS/MS). National Institute of Standards and Technology, 2025. https://doi.org/10.6028/nist.sp.1200-31-upd1.

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Shum, Sam. Measurement of elemental speciation by liquid chromatography -- inductively coupled plasma mass spectrometry (LC-ICP-MS) with the direct injection nebulizer (DIN). Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10115021.

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Browner, R. F. Fundamental studies with a monodisperse aerosol-based liquid chromatography/mass spectrometry interface (MAGIC-LC/MS). Final progress report, December 1, 1989--December 31, 1992. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/171264.

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Mayer, B., A. Williams, R. Leif, R. Udey, and A. Vu. Extraction of Sulfur Mustard Metabolites from Urine Samples and Analysis by Liquid Chromatography-High-Resolution Mass Spectrometry (LC-HRMS). Office of Scientific and Technical Information (OSTI), 2014. http://dx.doi.org/10.2172/1165796.

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