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Dissertations / Theses on the topic 'LCMV'

Author: Grafiati

Published: 4 June 2021

Last updated: 21 February 2023

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1

Gould, Maule Graham. "Investigation of Host Factors Required for Lymphocytic Choriomeningitis Virus Entry." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39145.

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Lymphocytic choriomeningitis virus (LCMV) is an old-world arenavirus capable of causing severe diseases in humans. Despite the extensive use of LCMV in studying immune responses to viral infection, very little is known about its entry pathway. As an enveloped virus, the main determinant of LCMV entry is the viral glycoprotein, which allows for the fusion of the viral membrane with that of the target cell, upon specific triggers. While the exact triggers for LCMV GP are currently unknown, low pH and interaction with a yet to be identified host-encoded receptor are likely involved in the activat

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2

Tsiakas, Konstantinos. "Ex-vivo-Untersuchungen des LCMV-Tropismus in eukaryotischen Zelllinien." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=964298147.

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3

Jung, So Ri. "Parsing the roles of innate and adaptive immunity in lethal, type I interferon-driven, immunopathological disease in LCMV-infected STAT KO mice." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/19816.

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Type I interferons (IFN-I) have paradoxical roles in immune responses. While being key mediators of host responses to infectious agents and immunomodulators of innate and adaptive immunity through activation of interferon-stimulated gene factor 3 (ISGF3), a complex of STAT1, STAT2 and IRF9, these cytokines have pathological roles in autoinflammatory disorders. In parallel to the canonical signaling pathway, many reports highlight the pathophysiological roles of non-ISGF3, alternative IFN-I signaling pathways. Previously, the Campbell lab showed that unlike WT mice, STAT1 knock-out (KO) mice de

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4

Ferreira, Júnior Ronaldo Sebastião. "Unscented transform performance assessment of adaptive lcmv filters and radioaltimeters." reponame:Repositório Institucional da UnB, 2015. http://dx.doi.org/10.26512/2015.5.D.22025.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Tecnologia, Departamento de Engenharia Elétrica, Programa de Pós-graduação em Engenharia Elétrica, 2015.<br>Submitted by Fernanda Percia França (fernandafranca@bce.unb.br) on 2015-12-11T17:51:34Z No. of bitstreams: 1 2015_RonaldoSebastiãoFerreiraJúnior.pdf: 1464987 bytes, checksum: dc18ed72fcd991f7fcc3803de1044643 (MD5)<br>Approved for entry into archive by Raquel Viana(raquelviana@bce.unb.br) on 2016-12-21T14:49:04Z (GMT) No. of bitstreams: 1 2015_RonaldoSebastiãoFerreiraJúnior.pdf: 1464987 bytes, checksum: dc18ed72fcd991f7fcc3

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5

Lee, Ellen. "Characterization of TGF-beta regulation during chronic infection with LCMV." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1467915.

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Thesis (Ph. D.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed September 15, 2009). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 44-51).

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6

Bunztman, Adam, Benjamin Vincent, Harsha Krovi, Shaun Steele, and Jeffrey Frelinger. "The LCMV gp33-specific memory T cell repertoire narrows with age." BioMed Central, 2012. http://hdl.handle.net/10150/610159.

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BACKGROUND:The memory response to LCMV in mice persists for months to years with only a small decrease in the number of epitope specific CD8 T cells. This long persistence is associated with resistance to lethal LCMV disease. In contrast to studies focused on the number and surface phenotype of the memory cells, relatively little attention has been paid to the diversity of TCR usage in these cells. CD8+ T cell responses with only a few clones of identical specificity are believed to be relatively ineffective, presumably due to the relative ease of virus escape. Thus, a broad polyclonal respons

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7

Kremer, Marcel [Verfasser]. "Immunoproteasome assembly in the brain of LCMV-infected mice / Marcel Kremer." Konstanz : Bibliothek der Universität Konstanz, 2009. http://d-nb.info/1021315702/34.

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8

Lee, L. N. "Characterization of type 1 interferon production during persistent lymphocytic choriomeningitis virus (LCMV) infection." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445734/.

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Type 1 interferons (B5N-a/ps), are innate cytokines possessing important immunomodulatory and effector roles in the innate and adaptive response. They are transiently induced to very high levels during the initial stages of many viral infections. However, regulation of EFN-a/p production during persistent viral infections is not well understood. This project aimed to address these issues using the murine lymphocytic choriomeningitis virus (LCMV) infection model. Initial objectives were to develop assays that would allow characterisation of the EFN-a/p response during chronic LCMV infection in

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9

Riera, Domínguez María Graciela. "Linking cell dynamics with coexpression networks to characterize key events in chronic virus infection." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/665626.

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The host immune response against infection requires the coordinated action of many diverse cell subsets that dynamically adapt to a pathogen threat. Due to the complexity of such a response, most immunological studies have focused on a few genes, proteins, or cell types. With the development of “omic”-technologies and computational analysis methods, attempts to analyse and understand complex system dynamics are now feasible. However, the decomposition of transcriptomic data sets generated from complete organs remains a major challenge. Here, we combined Weighted Gene Coexpression Network Analy

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10

Klein, de Licona Hannah Washington. "Congenital LCMV virus: mechanism of brain disease in a rat model of congenital viral infection." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/531.

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Lymphocytic choriomeningitis virus (LCMV) infection during pregnancy severely injures the human fetal brain. Neonatal rats inoculated with LCMV are an excellent model of congenital LCMV infection, as they develop neuropathology, including cerebellar injuries, similar to those seen in humans. The goal of this thesis was to determine what underlies brain injury and the differential immune response and to determine the role of T-cells in LCMV induced pathology. First, I examined whether cytokine and chemokine expression after LCMV infection was higher in the cerebellum and olfactory bulbs, which

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11

Paillard, Michelle Arlette [Verfasser], Thomas [Gutachter] Wunderlich, and Peter [Gutachter] Kloppenburg. "The impact of myeloperoxidase on LCMV-induced immunopathology / Michelle Arlette Paillard ; Gutachter: Thomas Wunderlich, Peter Kloppenburg." Köln : Universitäts- und Stadtbibliothek Köln, 2019. http://d-nb.info/1213896924/34.

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12

Olesin, Elizabeth A. "Transcriptional Regulation of Effector and Memory Responses during Acute and Chronic Lymphocytic Choriomeningitis Virus (LCMV) Infection." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/1000.

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Transcriptional regulation of CD8+ T cell differentiation during acute and chronic viral infections is an intricate web made up of many of transcription factors. While several transcription factors have been elucidated in this process, there are still many more that remain elusive. In this work, we look into the role of two transcription factors, IRF4 and Runx2, and their role in CD8+ T cell terminal effector cells and memory precursor cells during acute LCMV-Armstrong infection. We found that IRF4 expression was regulated by TCR signal strength during infection, and that IRF4 expression level

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13

Dunbar, Erin. "An evaluation of the efficiency of lymphocytic choriomeningitis virus - nucleoprotein cross priming in vivo." Thesis, Kingston, Ont. : [s.n.], 2007. http://hdl.handle.net/1974/439.

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14

Plume, Jeffrey Michael. "The role of viral strain in a congenital brain infection." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/2130.

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Lymphocytic Choriomeningitis Virus (LCMV) is a common arenavirus and natural murine pathogen that causes congenital neurodevelopmental disease in humans. Exposure to the virus in utero often results in severe and permanent damage the fetal brain and eyes. While usually severe, symptoms vary from case to case. Little is known about the pathological mechanism of congenital LCMV disease. Animal models of congenital LCMV infections suggest that timing of infection during gestation may influence disease outcomes; however, time alone cannot explain all of the variation observed in humans. Another po

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15

Lin, Adora A. "The CD4+ T cell response to CNS viral infection." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1235330516.

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16

Moran, Michael. "Moving in for the Kill: Natural Killer Cell Localization in Regulation of Humoral Immunity." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1460446618.

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17

Polz, Robin Thomas Siegfried [Verfasser]. "Die Rolle des Interleukin-6 Trans-Signalweges bei einer akuten LCMV-Infektion und Beteiligung am Leberschaden / Robin Thomas Siegfried Polz." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2020. http://d-nb.info/1211813967/34.

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18

Dhenni, Rama B. S. "Role of Granzyme B in the Susceptibility to Secondary Bacterial Infection after Viral Infection." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1460446984.

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19

Lemos, Sara Sofia de Campos Pereira. "CD8 T cell differentiation during immune responses." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T009/document.

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Les lymphocytes T CD8 ont un rôle essentiel dans la protection contre les agents pathogènes intracellulaires et la progression tumorale. Ainsi, la compréhension de la diversité des mécanismes de différenciation des lymphocytes T CD8 naïfs en cellules effectrices, ainsi qu’en cellules mémoires compétentes, est fondamentale pour le développement efficace de vaccins à cellules T. Dans ce travail de thèse, nous avons abordé deux questions centrales : (1)Très tôt après l’activation des cellules T CD8, quels sont les mécanismes par lesquels les cellules T effectrices agissent comme effecteurs pro-in

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20

Wingerath, Jessica [Verfasser], Thomas [Akademischer Betreuer] Wirth, and Reinhard [Akademischer Betreuer] Schwinzer. "Funktionelle Charakterisierung von rekombinanten LCMV-Vektoren für die Therapie von Infektions- und Tumorerkrankungen / Jessica Wingerath ; Akademische Betreuer: Thomas Wirth, Reinhard Schwinzer ; Klinik für Gastroenterologie, Hepatologie und Endokrinologie." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2018. http://d-nb.info/1159909059/34.

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21

De, Campos Pereira Lemos Sara Sofia. "CD8 T cell differentiation during immune responses." Phd thesis, Université René Descartes - Paris V, 2014. http://tel.archives-ouvertes.fr/tel-01059806.

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CD8 T cells are essential for the elimination of intracellular pathogens and tumor cells. Understanding how naïve CD8 T cells differentiate into effector cells capable of eliminating pathogens and to generate adequate memory cells during immune responses is fundamental for optimal T cell vaccine design. In this PhD thesis work we addressed two central questions: 1) What are the mechanisms by which early effector T cells could act as pro-inflammatory effectors? And what is their role in the immune response? 2) How heterogeneous are CD8 responses? Could different pathogens modulate CD8 T cell di

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22

Li, Wen. "Investigation of Type I Interferon Signaling in the Cellular Response and Host Defense." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/10615.

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Type I interferons (IFN-I) mediate the antiviral host response through activation of interferon-stimulated gene factor 3 (ISGF3) complex consisting of STAT1, STAT2 and IRF9. However, IFN-I can activate a number of non-canonical signaling pathways, which may contribute to neurological diseases in transgenic mice with CNS-production of IFN-α. It remained largely unknown how and to what extent non-canonical signaling pathways mediate the functional effects of IFN-I. Thus, the role of IFN-α-stimulated ISGF3-independent gene regulation was investigated in murine primary mixed glial cells (MGCs) in

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23

LEGRAND, Nicolas. "Sélection centrale, survie et sélection périphérique des lymphocytes T ab CD8+." Phd thesis, Université Pierre et Marie Curie - Paris VI, 2002. http://tel.archives-ouvertes.fr/tel-00001512.

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La composition des compartiments lymphocytaires T est soumise à de constantes modifications, sous l'effet conjugué de la production de nouvelles spécificités, de la sélection lors d'une rencontre avec un antigène et de la mort cellulaire. Face à ces flux de cellules entre les différents compartiments centraux et périphériques, les mécanismes de la régulation homéostatique assurent le fait que le système immunitaire se maintienne à l'équilibre. A l'image d'un écosystème, on peut alors observer que les lymphocytes T entrent en compétition les uns avec les autres pour des niches de sélection et d

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24

Silva, Jean Carlo de Sousa e. "Aplicação do mínimo múltiplo comum generalizado nas ondas de pêndulos." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/5719.

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Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2016-07-14T12:48:19Z No. of bitstreams: 2 Dissertação - Jean Carlo de Sousa e Silva - 2016.pdf: 1067779 bytes, checksum: b4f60747c4efb9967cd66d2dba3afc20 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-07-14T12:49:42Z (GMT) No. of bitstreams: 2 Dissertação - Jean Carlo de Sousa e Silva - 2016.pdf: 1067779 bytes, checksum: b4f60747c4efb9967cd66d2dba3afc20 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)

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Lorenz, Anja. "Kooperationsunterstützung in einem Learning Content Management System (LCMS)." Universitätsbibliothek Chemnitz, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-82022.

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Learning Content Management Systeme (LCMS) unterstützen die professionelle Erstellung, Verwaltung und Auslieferung von Lernmaterialien [BHMH02]. Die Speicherung der hierfür verarbeiteten Lerninhalte in einem zentralen Repository ermöglicht neben deren Wiederverwendung auch den Zugriff für mehrere Nutzer und somit das Zusammenführen der verschiedenen Kompetenzen, die während der Erstellung benötigt werden: Die mithilfe der Lernmaterialien zu vermittelnden Inhalte müssen nicht nur fachlich richtig, sondern auch didaktisch, gestalterisch und technisch für ein oder mehrere Zielgruppen individuell

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Lorenz, Anja. "Unterstützung der Nutzung des kollektiven Wissens in einem LCMS." Universitätsbibliothek Chemnitz, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-70694.

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Bei der Erstellung von Lernmaterialien für die Aus- und Weiterbildung in Unternehmen treffen verschiedene Anforderungen aufeinander: Die Kursmaterialien sollen fachlich richtig, didaktisch sinnvoll und gestalterisch ansehnlich aufbereitet sein. Zugleich finden sich in den Unternehmen unterschiedliche Zielgruppen und Einsatzzwecke, sodass hohe Ansprüche an den effektiven Einsatz und somit an die Wiederverwendbarkeit einmal erstellter Lerninhalte bestehen. Learning Content Management Systeme (LCMS) begegnen diesen Herausforderungen und stellen Funktionalitäten zur Erstellung, Bearbeitung, Verwal

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Soltan, Soltan. "Interaction of superconductivity and ferromagnetism in YBCO-LCMO heterostructures." Göttingen Cuvillier, 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=97407683X.

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Bonilha, Marcel Miyamura [UNESP]. "Estudo das propriedades de super-redes YBCO/isolante/LCMO." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/143822.

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Submitted by MARCEL MIYAMURA BONILHA null (marcelmb@gmail.com) on 2016-09-08T10:39:53Z No. of bitstreams: 1 Versão Final.pdf: 4946368 bytes, checksum: 4675d9707acb564334a7be7744822ddf (MD5)<br>Approved for entry into archive by Juliano Benedito Ferreira (julianoferreira@reitoria.unesp.br) on 2016-09-09T12:47:33Z (GMT) No. of bitstreams: 1 bonilha_mm_me_bauru.pdf: 4946368 bytes, checksum: 4675d9707acb564334a7be7744822ddf (MD5)<br>Made available in DSpace on 2016-09-09T12:47:33Z (GMT). No. of bitstreams: 1 bonilha_mm_me_bauru.pdf: 4946368 bytes, checksum: 4675d9707acb564334a7be7744822ddf (MD

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Bonilha, Marcel Miyamura. "Estudo das propriedades de super-redes YBCO/isolante/LCMO /." Bauru, 2016. http://hdl.handle.net/11449/143822.

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Orientador: Dayse Iara dos Santos<br>Banca: Pablo Antonio Venegas Urenda<br>Banca: Nelcy Della Santina Mohallem<br>Resumo: Heteroestruturas que combinam camadas supercondutoras (SC) com ferromagnéticas (FM), e, em alguns casos, ainda com camadas isolantes (I) entre as primeiras, possuem propriedades que não são observadas para os filmes isolados devido a interação entre elas. Este trabalho busca contribuir para a elucidação das propriedades de super-redes do tipo SC/I/FM feitas por PLD (Pulsed Laser Deposition), utilizando o YBa2Cu3O7-δ (YBCO) como supercondutor, o La2/3Ca1/3MnO3 (LCMO) como f

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Гуща, А. А. "LCMS-системи як новітній інструмент організації дистанційної навчальної діяльності". Thesis, ОНАХТ, 2021. https://openarchive.nure.ua/handle/document/19250.

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31

Betteridge, Benjamin Grant. "LCM Permeability Characterization Over Mold Curvature." BYU ScholarsArchive, 2020. https://scholarsarchive.byu.edu/etd/8508.

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Composite flow simulation tools for LCM processing can be expensive and time-consuming but necessary to design a mold system with proper placement of resin inlets and vacuum outlets. Composites manufacturing engineers would benefit from data regarding the impact of mold curvature radius on resin flow. This could help determine whether or not a particular part and mold would require expensive simulation software designed to handle complex flow paths through curved fabric architectures exhibiting variable permeability over the curvature, or if simple flow modeling would provide accurate enough s

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32

Lorenz, Anja. "Über kurz oder lang. Ein Schlichtungsversuch zur Debatte über Micro- und Macrolearning." Universitätsbibliothek Chemnitz, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-82098.

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Die Vorteile von Microlearning gegenüber langatmiger (Online-) Schulungen liegen auf der Hand: Sie führen schnell zu Lernerfolgen, unterbrechen den Alltag nur kurz und entsprechen der Kultur der „Net Generation“. Mit einem Blogeintrag stellte sich Gabi Reinmann [Rei10a] diesen Argumenten offen entgegen und sprach sich für die Notwendigkeit langer Lernphasen für eine umfassende Bildung aus. Dabei widersprechen sich die Lernkonzepte nicht, sondern können und müssen einander ergänzen. Auch die dafür benötigten Lernmaterialen sollten nicht isoliert voneinander erstellt werden: durch eine geeignete

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Soltan, Soltan [Verfasser]. "Interaction of superconductivity and ferromagnetism in YBCO-LCMO heterostructures / Soltan Soltan." Göttingen : Cuvillier, 2005. http://d-nb.info/97407683X/34.

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Xu, Liqun. "Integrated analysis of liquid composite molding (LCM) processes." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1095688597.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xix, 245 p.; also includes graphics. Includes bibliographical references (p. 233-245).

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Augustsson, Sjögren Daniel. "Characterisation of aptamers selected for binding to Yersinia pestis virulence protein LcrV." Thesis, Umeå universitet, Biomedicinsk laboratorievetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-58619.

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Michaud, François-Thomas. "Profilage protéomique par analyse multivariée de signaux LCMS appliqué en ingénierie cellulaire." Thesis, Université Laval, 2009. http://www.theses.ulaval.ca/2009/26366/26366.pdf.

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Geiger, Stephen Kurt. "Legacy Computing Markup Language (LCML) and LEGEND -- LEGacy Encapsulation for Network Distribution." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/33423.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 2004.<br>Includes bibliographical references (p. 131-133).<br>The rapid increase of computing power and emergence of distributed computing technologies such as Grid computing create new opportunities for scientific computing. One of the challenges faced in harnessing the emerging computational power is how to effectively use traditional command-line driven "legacy" codes within a networked framework; and a related challenge is how to make the operation of such codes a more user-friendly process. In this work a sp

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Melton, Tyler, and Stacy D. Brown. "Monitoring the Effects of Chlorination Treatment on Sulfamethazine using LCMS-IT-TOF." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/5291.

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He, Bin. "Techniques for studying the nuclear condition of giant cells induced by Meloidogyne species." Texas A&M University, 2004. http://hdl.handle.net/1969.1/3243.

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Nematodes of the genus Meloidogyne are known as Âroot-knotÂ nematodes due to the characteristic knots or galls found on the roots of infected plants. Root-knot nematodes attack over 2000 species of plants and cause over 80 billion dollars lost annually. Giant cells are feeding sites of root-knot nematodes and are enlarged multinuclear cells induced by the nematodes in susceptible host roots and that function to provide nutrients to the nematode. This thesis presents data on two techniques of studying the nuclear condition in giant cells. Colchicine was used to arrest mitosis in giant cells i

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Teixeira, Renata Beltr?o. "Fermenta??o alco?lica utilizando l?quido da casca de coco verde como fonte de nutrientes." Universidade Federal do Rio Grande do Norte, 2007. http://repositorio.ufrn.br:8080/jspui/handle/123456789/15739.

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Made available in DSpace on 2014-12-17T15:01:12Z (GMT). No. of bitstreams: 1 RenataBT.pdf: 1220401 bytes, checksum: a52c88053d4d3cde9e007821b799d056 (MD5) Previous issue date: 2007-06-15<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>The liquid of the rind of green coconut (LCCV), an effluent stream from the industrial processing of green coconut rind, is rich in sugars and is a suitable feedstock for fermentation. The first step of this study was to evaluate the potential of natural fermentation of LCCV. As the literature did not provide any information about LCCV and d

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Lorenz, Anja. "Über kurz oder lang. Ein Schlichtungsversuch zur Debatte über Micro- und Macrolearning." Hochschule Zittau/Görlitz, 2010. https://monarch.qucosa.de/id/qucosa%3A19644.

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Die Vorteile von Microlearning gegenüber langatmiger (Online-) Schulungen liegen auf der Hand: Sie führen schnell zu Lernerfolgen, unterbrechen den Alltag nur kurz und entsprechen der Kultur der „Net Generation“. Mit einem Blogeintrag stellte sich Gabi Reinmann [Rei10a] diesen Argumenten offen entgegen und sprach sich für die Notwendigkeit langer Lernphasen für eine umfassende Bildung aus. Dabei widersprechen sich die Lernkonzepte nicht, sondern können und müssen einander ergänzen. Auch die dafür benötigten Lernmaterialen sollten nicht isoliert voneinander erstellt werden: durch eine geeignete

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Blanchette, Maxime. "Development of a method for the LCMS determination of vicinal diketones in beer." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100772.

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No existent analytical method allowed the determination of the vicinal diketones (VDK), 2,3-butanedione (diacetyl) and 2,3-pentanedione, by liquid chromatography/mass spectrometry (LC/MS). An LC/MS method was developed for the simultaneous determination of diacetyl and 2,3-pentanedione in beer. A method allowing the determination of the amino acids (AA) related to the formation of VDK during fermentation was also developed. VDK were derivatized with o-phenylenediamine (OPDA) to form quinoxaline compounds. The reaction of VDK with OPDA was studied to optimize reaction time. Conversion of the di

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Felts, Jennifer Elaine. "An evaluation of extraction parameters and LCMS analysis of oligonucleotides from biological matrices." View electronic thesis, 2008. http://dl.uncw.edu/etd/2008-3/r1/feltsj/jenniferfelts.pdf.

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Roberts, Joanne B. "Determination and identification of drug and chemical metabolites in waste water by LCMS/MS." Thesis, Glasgow Caledonian University, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726806.

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Pouliot, Kimberly Lea. "Surface of Yersinia pestis: LCRV, F1 Production, Invasion and Oxygen: A Dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/358.

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Of the eleven species of bacteria that comprise the genus Yersinia of the family Enterobacteriaceae, three species are pathogenic for humans. Yersinia pseudotuberculosis and Yersinia enterocolitica usually cause a mild, self-limiting mesenteric lymphadenitis or ileitis. Yersinia pestis causes a highly invasive often fatal disease known as plague. All three elaborate a type three secretion system that is essential for virulence and encoded on closely related plasmids. In Y. pestis, all the effectors, structural components and chaperones are encoded on the 70kb plasmid, pCD1. Of these, LcrV from

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Brown, Stacy D., J. T. Connor, N. C. Smallwood, and Ralph A. Lugo. "Quantitative Determination of Lansoprazole for Stability Study in Oral Suspensions Using LCMS-IT-TOF." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etsu-works/5293.

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Lorenz, Anja, and Lars Fassmann. "Lernmaterialien effektiv aufbereiten und wiederverwenden." Universitätsbibliothek Chemnitz, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-82101.

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Hochwertige Schulungsmaterialien für die unternehmensinterne Weiterbildung sind ein erster wichtiger Schritt hin zu einem effektiven Wissensmanagement. Einmal erstellt, können digitale Lerninhalte immer wieder eingesetzt werden. Allerdings ist die Pflege und Anpassung an die Anforderungen verschiedener Zielgruppen und Auslieferungsformate mit herkömmlicher E-Learning-Autorensoftware sehr aufwändig. Nicht so bei serverbasierter Software – sie ermöglicht die Planung, Erstellung, Auslieferung, Verwaltung und Pflege wiederverwendbarer digitaler Lernmaterialien. Dies ist der Ausgangspunkt für eine

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Herrler, Michael. "Yersinia-LCRV induzierte NFKB-Aktivierung über die Toll-Like-Rezeptoren (TLR)1, TLR2 imd TLR6." kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/9435/.

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Herrler, Michael. "YERSINIA-LCRV INDUZIERTE NFΚB-AKTIVIERUNG ÜBER DIE TOLL-LIKE-REZEPTOREN (TLR)1, TLR2 UND TLR6". Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-94350.

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Nghiem, Van Tuan. "Impact du changement du mode d'occupation des sols sur le fonctionnement hydrogéochimique des grands bassins versants : cas du bassin versant de l'Ain." Thesis, Grenoble, 2014. http://www.theses.fr/2014GRENU009/document.

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La France, à l'instar de nombreux pays européens, connaît un recul assez net de sa population paysanne et par la même occasion de son potentiel agricole. Cette baisse sensible, enregistrée sur les trente dernières années est la conséquence directe de l'exode massif des populations vers les grandes agglomérations. Cette mutation s'est accompagnée de la fermeture progressive des paysages, marqués le plus souvent par une colonisation rapide par des espèces forestières. Ces évolutions sont également dues au changement climatique qui favorise certaines espèces par rapport à d'autres. Du point de vu

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