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1

Batmaz, Ahmet, Türkan Paşalı Kilit, and Celal Kilit. "The effect of anxiety on metabolic parameters in patients with primary hypertension." Journal of Cardiology & Cardiovascular Surgery 2, no. 3 (2024): 42–47. http://dx.doi.org/10.51271/jccvs-0035.

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Aims: Although the role of anxiety in the pathogenesis of hypertension is known, the effect of anxiety on metabolic parameters in hypertension has not been demonstrated. This study aimed to evaluate the effect of anxiety on metabolic parameters and blood pressure regulation in patients with primary hypertension. Methods: The study was designed as a single-center, descriptive cross-sectional study. A total of 150 patients receiving antihypertensive therapy for primary hypertension were included in the study. Patients were divided into minimal, mild, moderate, and severe anxiety groups according
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2

Munkhaugen, John, Jan Erik Otterstad, Toril Dammen, et al. "The prevalence and predictors of elevated C-reactive protein after a coronary heart disease event." European Journal of Preventive Cardiology 25, no. 9 (2018): 923–31. http://dx.doi.org/10.1177/2047487318768940.

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Objective An interleukin-beta antagonist reduces the risk of subsequent cardiovascular events in coronary patients with high-sensitivity C-reactive protein (hs-CRP) ≥2 mg/L. It remains to be defined how large the coronary population at inflammatory risk is, and what the predictors of elevated risk are. Methods A cross-sectional study investigated the proportion of patients with elevated hs-CRP (i.e. ≥2 mg/L) and the respective demographic and clinical predictors in 971 patients without concomitant inflammatory diseases who had been hospitalized with myocardial infarction (80%) and/or a revascu
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BÜYÜKŞİRECİ, Mehmet, Dilek EKER BÜYÜKŞİRECİ, and Ayşe Gülşen DOĞAN. "Evaluation of carotid intima-media thickness of female fibromyalgia patients and determination of their relationship with disease activity, severity of fibromyalgia, anxiety and depression levels." Anatolian Current Medical Journal 5, no. 1 (2023): 47–52. http://dx.doi.org/10.38053/acmj.1205466.

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Aim: Carotid artery intima-media thickness is thought strong predictor of cardiovascular diseases. To evaluate the common carotid artery intima-media thickness (CCIMT) in female patients with fibromiyalgia (FM) and determine its relationship with disease activity, severity of fibromyalgia, anxiety and depression levels.Material and Method: Thirty nine patients who had fibromyalgia syndrome according to 2016 American College of Rheumatology (ACR) classification criteria and 41 healthy controls were included. Pain level and disease activities were assessed with Numerical Rating Scale (NRS) and F
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4

Solak, Hatice, and Merve Akkuş. "Exploring the relationship between serum LOX-1, Ox-LDL, and generalized anxiety disorder." Journal of Affective Disorders 378 (June 2025): 74–80. https://doi.org/10.1016/j.jad.2025.02.089.

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Barbosa, Caroline da Silva, Magno Conceição das Merces, Amália Ivine Costa Santana, et al. "Anxiety and dyslipidemia among primary health care professionals: A Cross-sectional study." Work 71, no. 3 (2022): 739–48. http://dx.doi.org/10.3233/wor-205095.

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BACKGROUND: Cross-sectional studies point out important evidence between anxiety and dyslipdemic disorders in health workers. OBJECTIVE: Our main objective was to estimate the association between anxiety and dyslipidemia in Primary Health Care (PHC) nursing professionals in Feira de Santana, Bahia, Brazil. METHODS: A confirmatory cross-sectional study involving 376 PHC nursing professionals. Data collection occurred through the application of a questionnaire containing sociodemographic, labor and lifestyle issues, and the Beck Inventory for anxiety; to evaluate the lipid profile, the HDL-c, LD
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Petyunina, O. V., M. P. Kopytsya, I. R. Vyshnevska та P. O. Petiunin. "Порівняльний аналіз субклінічного тривожно-депресивного синдрому в пацієнтів із гострим інфарктом міокарда з елевацією сегмента ST до та під час активних бойових дій у Харківській області". Ukrainian Journal of Cardiology 31, № 2 (2024): 21–31. http://dx.doi.org/10.31928/2664-4479-2024.2.2131.

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The aim – to assess subclinical emotional distress in patients with ST-Elevation Myocardial Infarction (STEMI) before and during the ongoing conflict in the Kharkiv Region. Materials and methods. The study encompassed 242 patients exhibiting subclinical emotional distress and hospitalized with STEMI at «L.T. Malaya TNI of NAMSU» before active conflict, compared with 65 patients during the conflict. Adherence to ethical standards was ensured, in line with the 1964 Helsinki Declaration, and the protocol received approval from the local ethics committee (Protocol № 8, dated 29.08.2016, and Protoc
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Das, Mridul, Nikhil Chandra Mondal, Arunima Chaudhuri, and Daniel Saldanha. "A Study to Observe the Impact of Depression, Anxiety, and Stress Levels on the Cardiovascular Profile in Elderly Patients Attending a Peripheral Medical College of a Developing Country." Journal of the Scientific Society 51, no. 2 (2024): 198–203. http://dx.doi.org/10.4103/jss.jss_38_23.

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Background: Cardiovascular disease is one of the leading causes of death worldwide, more so in an aging population with mental health issues. Objectives: We aimed to study the influence of depression, anxiety, and stress levels on the cardiovascular profile in elderly patients attending a peripheral medical college in West Bengal. Methodology and Participants: This cross-sectional study was conducted in a peripheral medical college among 197 elderly participants. The cardiovascular profile was examined and Depression, Anxiety, and Stress Scale-21 scores were estimated. Results: One hundred and
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Erikson, Keith M., Kristina El-Khouri, Radmila Petric, et al. "Carbon Nanodots Attenuate Lipid Peroxidation in the LDL Receptor Knockout Mouse Brain." Antioxidants 12, no. 5 (2023): 1081. http://dx.doi.org/10.3390/antiox12051081.

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Abnormal cholesterol metabolism can lead to oxidative stress in the brain. Low-density lipoprotein receptor (LDLr) knockout mice are models for studying altered cholesterol metabolism and oxidative stress onset in the brain. Carbon nanodots are a new class of carbon nanomaterials that possess antioxidant properties. The goal of our study was to evaluate the effectiveness of carbon nanodots in preventing brain lipid peroxidation. LDLr knockout mice and wild-type C57BL/6J mice were treated with saline or 2.5 mg/kg bw of carbon nanodots for a 16-week period. Brains were removed and dissected into
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Dai, Wenhui, and Qiaolin Peng. "Efficacy of Dapagliflozin Combined with Lifestyle Intervention in Obesity Control." Computational and Mathematical Methods in Medicine 2022 (May 13, 2022): 1–5. http://dx.doi.org/10.1155/2022/7745873.

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Objective. To explore the best treatment of obesity in middle and old age. Methods. 80 obese patients in our hospital from January 2020 to December 2021 were randomly divided into the control group and the intervention group according to the numerical table method. The control group was treated with lifestyle intervention, while the intervention group was treated with dapagliflozin combined with lifestyle intervention. The effects of body weight, body mass index (BMI), waist circumference, and blood lipids (LDL, HDL, TC, and TG) were measured and compared. Anxiety and depression scores were as
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Podzolkov, V. I., A. E. Bragina, L. V. Vasil’eva, Yu P. Grintsevich, and Yu N. Rodionova. "Adherence to statin therapy in patients with high and very high cardiovascular risk in real clinical practice." Sechenov Medical Journal 11, no. 1 (2020): 38–48. http://dx.doi.org/10.47093/2218-7332.2020.11.1.38-48.

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Despite the proven efficacy of lipid-lowering therapy, adherence to long-term statin therapy in patients with cardiovascular disease remains low.Aim. To study adherence to long-term statin therapy and factors associated with adherence in patients with high and very high cardiovascular risk (CVR) in real clinical practice.Materials and methods. The single-center cohort study included 53 patients (mean age 68.1 ± 10.2 years) with high or very high CVR on the SCORE scale and have been taking statins for at least 3 months prior to inclusion in the study. The level of low-density lipoprotein choles
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Méndez-Cruz, Bruno Eduardo, Ana Laura Hernández-Ledesma, Juan Carlos Solís-Sainz, Norma Angélica Rivera Villaseñor, Lilia Susana Gallardo-Vidal, and Adriana Jheny Rodríguez-Méndez. "Presencia de ansiedad y depresión en personas con diabetes tipo 2y esclerosis múltiple en Querétaro, México." Digital Ciencia@UAQRO 18, no. 1 (2025): 99–123. https://doi.org/10.61820/dcuaq.2395-8847.v18n1.1733.

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The prevalence of anxiety and depression in patients with chronic diseases is of concern, since there is evidence that it increases the severity of conditions such as diabetes and autoimmune diseases and is associated with a lower response to treatments, although unfortunately there are no clear studies that mention prevalence data. For these reasons, anxiety and depression were evaluated in people from Querétaro with diagnosed type 2 Diabetes (T2D) and Multiple Sclerosis (MS). Anxiety and symptomatic depression were evaluated using Beck Anxiety Inventory and Beck Depression Inventory in 20 pa
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Wolever, Thomas M. S., Maike Rahn, El Hadji Dioum та ін. "Effect of Oat β-Glucan on Affective and Physical Feeling States in Healthy Adults: Evidence for Reduced Headache, Fatigue, Anxiety and Limb/Joint Pains". Nutrients 13, № 5 (2021): 1534. http://dx.doi.org/10.3390/nu13051534.

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The gastrointestinal (GI) side-effects of dietary fibers are recognized, but less is known about their effects on non-GI symptoms. We assessed non-GI symptoms in a trial of the LDL-cholesterol lowering effect of oat β-glucan (OBG). Participants (n = 207) with borderline high LDL-cholesterol were randomized to an OBG (1 g OBG, n = 104, n = 96 analyzed) or Control (n = 103, n = 95 analyzed) beverage 3-times daily for 4 weeks. At screening, baseline, 2 weeks and 4 weeks participants rated the severity of 16 non-GI symptoms as none, mild, moderate or severe. The occurrence and severity (more or le
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Burokienė, Neringa, Dovilė Karčiauskaitė, Vytautas Kasiulevičius, Vaidutis Kučinskas, and Zita Aušrelė Kučinskienė. "Manifestation of anxiety and depression and their association with cardiovascular diseases in the Lithuanian population." Acta medica Lituanica 21, no. 3 (2014): 123–30. http://dx.doi.org/10.6001/actamedica.v21i3.2996.

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Background. Cardiovascular diseases (CVD) continue to be the leading cause of morbidity and mortality in Lithuania. The key modifiable factors identified for CVD prevention include lifestyle and behavior factors (e. g. diet, body weight, physical activity, cigarette smoking), and health risk factors (e. g. hypertension, hypercholesterolemia, etc.), also anxiety and depression are considered as potentially modifiable CVD risk factors as well. The aim of this study was to evaluate the association between psychosocial stress, manifested as anxiety and depression, and CVD. Material and methods. 31
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Sidorova, Yuliya S., Varuzhan A. Sarkisyan, Nikita A. Petrov, Yuliya V. Frolova, and Alla A. Kochetkova. "Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats." International Journal of Molecular Sciences 24, no. 8 (2023): 7643. http://dx.doi.org/10.3390/ijms24087643.

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The aim of this study was to investigate the effects of soybean lecithin and plasmalogens concentrating on a variety of physiological tests and biochemical analyses in healthy Wistar rats. For six weeks, male Wistar rats were given a standard diet that included plasmalogens or soybean lecithin. We measured anxiety levels, overall exploratory activity, short- and long-term memory, cognitive abilities, and grip strength. Lecithin increased significantly anxiety and enhanced memory and cognitive functions. Plasmalogens significantly improved appetite and increased grip strength. When compared to
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Chojnowska, Sylwia, Iwona Cabaj-Wiater, Aleksandra Mikulska-Baran, Beata Zalewska-Szajda та Napoleon Waszkiewicz. "Positive Correlation of Serum N-Acetyl-β-hexosaminidase with Markers of Atherosclerosis in Diabetes Type 2 Patients with Mild Symptoms of Depression and Anxiety". Disease Markers 2018 (20 червня 2018): 1–6. http://dx.doi.org/10.1155/2018/1760592.

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Background. Analysis of the correlation between diabetes type 2 (DT2) and serum N-acetyl-β-hexosaminidase (HEX) activity with parameters of fat metabolism and symptoms of anxiety and depression.Material and Method. The study was performed using a random sample of 40 DT2 patients (22 women and 18 men) between the ages of 43 and 71 (median 59) and 40 control persons (28 women and 12 men) between the ages of 18 and 64 (median 46). The activity of HEX was determined by a colorimetric method. The activity of the serum exoglycosidase was expressed in pkat/mL. Each participant underwent Hamilton test
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16

Zhang, Hong, Jun Ma, Jing Wang, Wenting Zhu, and Xuebing Liu. "Clinical features of overweight in acute-phase hospitalised major depressive disorder with comorbid anxiety: a cross-sectional study." BMJ Open 15, no. 2 (2025): e087640. https://doi.org/10.1136/bmjopen-2024-087640.

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ObjectiveThis study aimed to investigate the incidence of overweight in patients with major depressive disorder (MDD) comorbid anxiety during the acute phase and to explore associated factors.DesignCross-sectional study.SettingWuhan Mental Health Center, China, from July 2017 to August 2022.Participants737 hospitalised patients diagnosed with MDD in the acute phase with comorbid anxiety symptoms.Primary outcome measuresIncidence and clinical correlations of overweight (body mass index (BMI) ≥ 24).ResultsAmong the study population, 55.63% were classified as overweight. Binary logistic regressio
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Reich, Bernhard, Gunnar Treff, Andrea Podolsky, et al. "Effectiveness of the innovative Austrian phase III cardiac rehabilitation model on cardiovascular risk factors: a nationwide registry." Open Heart 12, no. 1 (2025): e003139. https://doi.org/10.1136/openhrt-2024-003139.

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IntroductionThe Austrian model of outpatient cardiac rehabilitation (CR) begins right after discharge from the acute care hospital. During phase II (OUT-II), it provides a facility-based, professionally supervised, multidisciplinary programme of 6 weeks. The subsequent, supervised phase III (OUT-III) lasts 6 months. In 2017, a 3–6 months lasting unsupervised home-based training has been added, which is followed by a 4-week facility-based evaluation and training period, called ‘refresher’. We aimed to assess the effectiveness of this programme using a nationwide registry.MethodsAnthropometric d
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Saltar, Laode, Sitti Masriwati, Mimiyati Mimiyati, Merry Merry, Lisnawati Lisnawati, and Islamiyah Islamiyah. "Quality of Life of Uncontrolled Type 2 Diabetes Mellitus Patients And Related Factors in The Coastal Area of Kendari City." NurseLine Journal 9, no. 2 (2024): 90–98. https://doi.org/10.19184/nlj.v9i2.52553.

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Uncontrolled type 2 Diabetes Mellitus (DM) leads to serious complications that significantly impact patients' quality of life. This study aimed to evaluate the relationship between random blood sugar (RBS) levels, Low-Density Lipoprotein (LDL) cholesterol levels, blood pressure, stress levels, and family support with the quality of life of patients with uncontrolled type 2 DM in the coastal area of the Nambo Health Center. The quantitative cross-sectional study was used included 41 respondents from a population of 46 uncontrolled type 2 DM patients, selected using simple random sampling. Data
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Villamil-Salcedo, Valerio, Blanca E. Vargas-Terrez, Jorge Caraveo-Anduaga, et al. "Glucose and cholesterol stabilization in patients with type 2 diabetes mellitus with depressive and anxiety symptoms by problem-solving therapy in primary care centers in Mexico City." Primary Health Care Research & Development 19, no. 01 (2017): 33–41. http://dx.doi.org/10.1017/s1463423617000512.

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Aim The aim of this study was to determine if the problem-solving therapy (PST) helps control metabolic variables in patients with type 2 diabetes mellitus (T2DM) who show depressive and anxiety symptoms. Background T2DM is a chronic-degenerative multifactorial disease. It is considered one of the main public health problems in the world, and it represents an important social and economic burden. It is frequently associated with major depression and anxiety disorders, which are related with high glycated hemoglobin (HbA1c) concentrations and poor metabolic control. Method We initially included
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Tong, P., Y. H. Shi, Y. Yang, et al. "Clinical Characteristics, Metabolic Parameters, and Risk Factors for Suicide Attempts Vary with Untreated Major Depressive Disorder Duration." Depression and Anxiety 2023 (December 21, 2023): 1–9. http://dx.doi.org/10.1155/2023/4869276.

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Suicidal attempts (SAs) are common in major depressive disorder (MDD). However, only few studies have so far assessed how risk factors for SAs in patients with MDD might be related to the duration of untreated illness (DUI). We interviewed 1,718 drug-naive outpatients with MDD with first-episode SAs and divided them into groups that had and had not attempted suicide. DUI was used as an additional grouping criterion. The patients (20.14%; 346/1718) who had a history of SAs were older and had a longer DUI; lower educational level (middle school-educated only); more psychotic symptoms; higher sco
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Şahin, Musa, and Didem Yüzügüllü. "Outcomes of metabolic syndrome and anxiety levels in light and heavy smokers." PeerJ 13 (March 5, 2025): e19069. https://doi.org/10.7717/peerj.19069.

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Background This study aimed to assess the impact of smoking status, as measured by pack-years (PY), on components of metabolic syndrome while considering the influence of anxiety. Design This cross-sectional study was conducted at a smoking cessation clinic in Turkey, enrolling individuals who visited the clinic in 2022. The Fagerstrom Test for Nicotine Dependence and the State-Trait Anxiety Inventory were utilized as assessment tools, while metabolic syndrome parameters (body mass index, hypertension, hyperglycemia, dyslipidemia) were evaluated. Smoking status was classified based on pack-yea
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Dashko, M. O., O. O. Syzon, and І. S. Diskovky. "Studing the impact of COVID-19 on the progression of metabolic, neuroendocrine disorders and some immunological changes in women with acne." Ukrainian Journal of Dermatology, Venerology, Cosmetology, no. 1 (March 28, 2025): 17–24. https://doi.org/10.30978/ujdvk2025-1-17.

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Acne is a multifactorial chronic inflammatory disease with primary damage to the pilosebaceous unit and the polymorphic clinical manifestations associated with overproduction of sebaceous glands, pathological desquamation of the sebaceous epithelium of the sebum follicles, activation of saprophytic, conditionally pathogenic microorganisms, and psychoemotional disorders. This is undoubtedly one of the most common dermatoses in clinical practice, accounting for 20—25 % of dermatology consultations. Today, especially in wartime, acne vulgaris remains a socially important problem in approximately
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Pah, Bucuras, Buleu, et al. "The Importance of DS-14 and HADS Questionnaires in Quantifying Psychological Stress in Type 2 Diabetes Mellitus." Medicina 55, no. 9 (2019): 569. http://dx.doi.org/10.3390/medicina55090569.

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Background and Objectives: The comorbid association between type 2 diabetes mellitus (T2DM) and a psychological profile characterized by depression and/or anxiety has been reported to increase the risk of coronary heart disease (CAD), the most striking macrovascular complication of diabetes. The purpose of the present study was to quantify anxiety, depression and the presence of type D personality, and to correlate the scores obtained with cardiovascular risk factors and disease severity in diabetic patients. Materials and methods: The retrospective study included 169 clinically stable diabeti
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Tino Cordeiro, Dayane Cristine, Carlos Alexandre Molena Fernandes, Neide Derenzo, Raquel Tomiazzi Utrila, Greice Westphal Nardo, and Mariana Salvadego Águila Nunes. "Associação entre níveis de ansiedade e depressão em adultos com obesidade." Enfermería Global 23, no. 2 (2024): 83–121. http://dx.doi.org/10.6018/eglobal.587821.

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Objective: To verify the association between levels of anxiety and depression of participants in a Multidisciplinary Program for the Treatment of Obesity, with anthropometric variables; body composition; biochemical and hemodynamic parameters; and health-related physical fitness. Method: Quantitative, correlational, cross-sectional study carried out with adults who participated in the Multidisciplinary Program for the Treatment of Obesity in a municipality in the Northwest of Paraná. For data collection, anthropometric measurements were applied in July 2021; body composition; biochemical and h
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Mustafa Ali Abdulrahman, M. Adnan Telfah Mohmed, and Raghad Mohammed Abdul Rahman. "Physiological and biochemical study of the effect of Anxiety exam in the blood of students." Tikrit Journal of Pure Science 20, no. 1 (2023): 103–8. http://dx.doi.org/10.25130/tjps.v20i1.1142.

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This study was conducted on the students of the Faculty of Education / University of Samarra, Department of biology for the period of (10/ 11/ 2010 to 28/02/2011 ) study were divided into two groups only . Set before performing the exam results were compared to a group before the exam results with a group after the exam.
 The results were as follows.
 The study showed significant changes in terms in high blood pressure before the exam performance and exam performance after falling as well as significantly increased antioxidant represented by MDA before performing the exam and exam pe
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Chen, Xiaoyang, Yifei Wang, Li Zhang, and Xuegong Xu. "Construction and Evaluation of Neural Network Correlation Model between Syndrome Elements and Physical and Chemical Indexes of Unstable Angina Pectoris Complicated with Anxiety." Computational and Mathematical Methods in Medicine 2022 (August 21, 2022): 1–11. http://dx.doi.org/10.1155/2022/6217186.

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Objective. Syndrome elements are regarded as the smallest unit of syndrome differentiation, which is characterized by indivisibility and random combination. Therefore, it can well fit the goal of syndrome differentiation and unity. Methods. Clinical physicochemical indicators are important references for disease diagnosis, but they are often not used too much in the process of TCM syndrome differentiation. In the era of intelligence, communicating TCM syndrome differentiation at the macro level with physiological and pathological processes at the micro level (i.e., these clinical physicochemic
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Sirchak, Yelizaveta, and Svitlana Opalenyk. "Dynamics of Indicators of Psychoemotional Condition in Patients with Chronic Pancreatitis and Atherosclerosis on the Background of Intestinal Dysbiosis Correction." Galician Medical Journal 27, no. 1 (2020): E2020111. http://dx.doi.org/10.21802/gmj.2020.1.11.

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The article describes and analyzes the psycho-emotional state indicators in patients with chronic alcoholic pancreatitis and atherosclerosis against the complex therapy background with the use of probiotics and melatonin. All patients were performed clinical-laboratory studies: lipid profile study (determination of total blood plasma cholesterol (LC), triglycerides (TG), high-density lipoprotein (HDL) and low-density lipoproteins (LDL), atherogenicity coefficient (CA)); feces research on dysbiosis. The alcoholic etiology of chronic pancreatitis was determined based on anamnestic data and using
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Pariyana, Dewi Angrraini, Hanna Marsinta Uli, Dalilah, and Muhammad Aziz. "Physical And Mental Health Examination Of Lung Tb Patients Due To The Covid-19 Pandemic And Health Education In Increasing Patient Knowledge." International Journal Of Community Service 1, no. 3 (2021): 325–31. http://dx.doi.org/10.51601/ijcs.v1i3.56.

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Pulmonary tuberculosis is an infectious disease that is still a major global health problem. Pulmonary TB cases are one of the co-morbidities of death for COVID-19 patients. The increase in the prevalence of TB patients and the increase in the number of cases and deaths of COVID-19 will certainly have an impact on patients and their families. The spread of COVID-19 worries the public, causing feelings of pressure and anxiety which are a common response from people who are affected (either directly or indirectly). The purpose of this activity is to describe the health status of pulmonary TB pat
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Naomi, Ruth, Rusydatul Nabila Mahmad Rusli, Soo Huat Teoh, Hasnah Bahari, and Zainul Amiruddin Zakaria. "Remodulation Effect of Elateriospermum tapos Yoghurt on Metabolic Profile of Maternal Obesity Induced Cognitive Dysfunction and Anxiety-like Behavior in Female Offspring—An In Vivo Trial on Sprague Dawley Rats." Foods 12, no. 8 (2023): 1613. http://dx.doi.org/10.3390/foods12081613.

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Pre-pregnancy weight gain induces dysregulation in the metabolic profile of the offspring, thereby serving as a key factor for cognitive decline and anxiety status in the offspring. However, early probiotic supplementation during the gestational period is linked with improved metabolic health. At the same time, a natural plant known as Elateriospermum tapos (E. tapos) is proven to improve cognition and modulate the stress hormone due to its high concentration of flavonoids. However, the effects of medicinal plant integrated probiotics in F1 generations warrants further investigation. Thus, thi
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Shipelin, Vladimir A., Ekaterina A. Skiba, Vera V. Budayeva, et al. "Toxicological Characteristics of Bacterial Nanocellulose in an In Vivo Experiment—Part 1: The Systemic Effects." Nanomaterials 14, no. 9 (2024): 768. http://dx.doi.org/10.3390/nano14090768.

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Bacterial nanocellulose (BNC) is being considered as a potential replacement for microcrystalline cellulose as a food additive and a source of dietary fiber due to its unique properties. However, studies on the risks of consuming BNC in food are limited, and it is not yet approved for use in food in the US, EU, and Russia. Aim: This study aims to perform a toxicological and hygienic assessment of the safety of BNC in a subacute 8-week administration in rats. Methods: BNC was administered to male Wistar rats in doses of 0, 1.0, 10.0, and 100 mg/kg body weight for 8 weeks. Various parameters suc
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Assaf, Abdelrahman Abdelhakim, Amr Adel Haiba, Mohamed Attia Saad, Hossam Eldin Fathallah Elsawy, and Adel Abdelkareem Badawy. "Psychosocial Factors, Pro-Inflammatory Markers & Serum Lipids among Patients with Suicidal Ideation & Suicidal Attempts." Journal of Advances in Medicine and Medical Research 35, no. 16 (2023): 23–45. http://dx.doi.org/10.9734/jammr/2023/v35i165087.

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Background: Suicide is a worldwide serious problem. It is a leading cause of death, accounting for 1.3% of all deaths worldwide in 2019 and Approximately 703,000 people die by suicide every year. We aimed to study the personal, cognitive, psychosocial, personality traits, psychopathological, pro-inflammatory markers & serum lipids differences between patients with suicidal ideation and patients with suicidal attempts and to assess predictor factors that make suicidal ideation convert to suicidal attempt.
 Subjects and Methods: This cross-sectional case control study was carried on par
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Trubnikova, Olga A., I. V. Tarasova, A. S. Mamontova, E. S. Kagan, O. V. Maleva, and O. L. Barbarash. "Predictors of moderate cognitive disorders in patients with coronary heart disease and type 2 diabetes mellitus." Clinical Medicine (Russian Journal) 94, no. 1 (2016): 31–35. http://dx.doi.org/10.18821/0023-2149-2016-94-1-31-35.

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Aim. To study predictors of moderate cognitive disorders (MCD) in patients with coronary heart disease (CHD) and type 2 diabetes mellitus (DM2). Materials and methods. The study included 54 men with CPD and DM2 (mean age 56.8±4.5 years). Standard medical examination was supplemented by the assessment of cognitive status, characteristics of lipid and carbohydrate metabolism. Factors allegedly influencing MCD development included the patients’ age, education level, stenosis of carotid arteries, LV ejection fraction, arterial hypertension, insulin and HbAlc levels, HOMA and QUICKI indices, lipid
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Yau, Ka-Yin, Pui-Sze Law, and Chung-Ngok Wong. "Cardiac and Mental Benefits of Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet plus Forest Bathing (FB) versus MIND Diet among Older Chinese Adults: A Randomized Controlled Pilot Study." International Journal of Environmental Research and Public Health 19, no. 22 (2022): 14665. http://dx.doi.org/10.3390/ijerph192214665.

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(1) Background: The Mediterranean-DASH intervention for neurodegenerative delay (MIND) diet and forest bathing (FB) are first-line therapies for controlling hypertension. This study aimed to investigate the combined effects of a MIND diet and FB and MIND diet alone among older Chinese patients with hypertension. (2) Methods: Seventy-two participants aged >50 with stages 1 or 2 hypertension were randomly assigned to the MIND group (n = 23), MIND-FB group (n = 25), or control group (n = 24). Systolic blood pressure (SBP) (primary outcome), point-of-care tests for blood lipid panel and glucose
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Arshad, Nurul ‘Ain, Teoh Seong Lin, and Mohamad Fairuz Yahaya. "Stingless Bee Honey Reduces Anxiety and Improves Memory of the Metabolic Disease-induced Rats." CNS & Neurological Disorders - Drug Targets 19, no. 2 (2020): 115–26. http://dx.doi.org/10.2174/1871527319666200117105133.

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Background: Scientific studies support the evidence of the involvement of Metabolic Syndrome (MetS) in the progression of neurodegenerative diseases through oxidative stress. Consumption of antioxidant compounds was found to be beneficial for brain-health as it reduced the brain oxidative stress level and improved cognitive performance in animals. Stingless bee honey or locally known as Kelulut Honey (KH) has high phenolic content and is widely used as a food supplement. Objectives: In this study, we aimed to investigate the effects of KH on the brain of MetS-induced rats. Methods: Forty male
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Brazil, John Francis, Irene Gibson, Denise Dunne, et al. "Improved Quality of Life, Fitness, Mental Health and Cardiovascular Risk Factors with a Publicly Funded Bariatric Lifestyle Intervention for Adults with Severe Obesity: A Prospective Cohort Study." Nutrients 13, no. 11 (2021): 4172. http://dx.doi.org/10.3390/nu13114172.

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Background: Lifestyle modification is the cornerstone of management for patients with severe and complicated obesity, but the effects of structured lifestyle programmes on quality of life, anxiety and depression scores and cardiovascular risk factors are not well-described. We sought to describe changes in self-reported quality of life and mental health-related outcomes as well as cardiovascular risk factors in patients completing a 10-week multidisciplinary lifestyle-modification programme. Methods: We conducted a prospective cohort study of all patients referred from our bariatric service wh
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Mohammed, Dr Zainab Sajid. "Effects of Prazosin in Hematology Parameters and Lipid Profile in Rats (Rattus Norvegicus)." Medical Science Journal for Advance Research 1, no. 01 (2020): 18–24. http://dx.doi.org/10.46966/msjar.v1i01.8.

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Alpha blockers are characterize as one of the most therapies that used for treatment of several condition such as Raynaud's disease, hypertension, scleroderma , and one of the most treatments for treated continuing pelvic pain syndrome- continuing prostatitis and also be used to treat anxiety and panic disorder such as generalized anxiety, posttraumatic stress disorder (Raskind, et al.,2003) . This study was conducted at the laboratory of department of biology, faculty of science/university of Kufa , 40 male rats that was used. The present study was conducted to investigate the effect of Prazo
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Dr., Ban Hadi Mahmood, Huda Fadhil Jady Dr., and Suad Adnan Nashee Dr. "Side Effects on Pregnant Women and Evaluation of Prognostic Results after Three Years." Sarcouncil journal of Medical sciences 3, no. 1 (2024): 14–20. https://doi.org/10.5281/zenodo.10519726.

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Background: The negative results of pregnancy are the main cause of health and psychological problems resulting from mothers and long-term mothers in countries with low or medium incomes. Objective: This study was analyzed outcomes related to side effects on pregnant women and assessed prognostic results in the long term. Patients and methods: We conducted a cross-sectional study which specialized in patients with pregnant women for a period between April 6, 2022, to August 17, 2023, as their ages ranged between (25 and 45) years who underwent delivery operations in different hospitals in Iraq
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Talebi, Shokoofeh, Zamzam Paknahad, Mohammad Hashemi, and Akbar Hasanzadeh. "Antioxidant status and risk of coronary artery disease." Nutrition & Food Science 49, no. 4 (2019): 700–712. http://dx.doi.org/10.1108/nfs-04-2018-0113.

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Purpose Coronary artery disease (CAD) is developed by an insufficient supply of oxygen-rich blood to the myocardium. Recent studies have shown that increased oxidative stress has implicated in the pathogenesis of coronary atherosclerosis. Anxiety and CAD have a mutual relationship, as the effect of long-lasting anxiety on atherosclerosis and CAD is well known. The purpose of this study is to investigate the relationship between dietary / serum total antioxidant capacity and CAD. Design/methodology/approach A total of 160 male patients were enrolled in this cross-sectional study. Diagnosis and
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Krishna, Thanmaye, Prashanth Shetty, and Geetha B. Shetty. "EFFECT OF ASHGOURD JUICE ON ANTHROPOMETRIC AND BIOCHEMICAL VARIABLES AMONG HEALTHY VOLUNTEERS - A COHORT STUDY." International Journal of Advanced Research 12, no. 01 (2024): 568–77. http://dx.doi.org/10.21474/ijar01/18156.

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Background & Objective: Ash gourd has antioxidant, anti-inflammatory, analgesic, antiasthmatic, diuretic, nephroprotective, antidiabetic, hypolipidemic, and antimicrobial effects. Flavonoids, glycosides, saccharides, proteins, carotenes, β-sitosterol were the main components. Chemical analysis showed that the main sugars in the Benincasa hispida peels were galactose, glucose, xylose, and sorbose and the edible portion contains 96.3% moisture,0.12% acidity, and 0.5% minerals. The mineral content in ash gourd follows the order: Na>Ca>Fe>Zn>K>Mn, which are important for mainta
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Longo-Mbenza, Benjamin. "The Management of Acute Coronary Syndrome, Cardio-Metabolic Risk, Geriatric Syndrome, Inflammasome, Genetics, Challenges of Heart Failure And Cardiomyopathies In The Time Of Covid 19: Experience Of Lo." Clinical Case Reports and Clinical Study 5, no. 4 (2021): 1. http://dx.doi.org/10.61148/2766-8614/jccrcs/094.

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Objective: To describe the scientific management of acute coronary syndrome, cardio-metabolic risk, geriatric syndrome, inflammasome, genetics, challenges of heart failure and cardiomyopathies in the time of COVID-19. Methods The review of the literature provided evidence relating to the place of COVID-19, the origin of the immune storm, atherosclerosis, hepatic-vasculo-respiratory renal attacks and insulin resistance on the cardiovascular system. Lomo University of Research evaluated structural markers, bio-markers of coinfection, oxidative stress, anxiety-depressive syndrome, inflammation, b
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Brambila-Tapia, Aniel Jessica Leticia, Ana Lilia Jacquez-Castañeda, Laura Arely Carrillo-Delgadillo, et al. "Association between Psychological, Biochemical and Personal Factors with the Inflammatory Marker High-Sensitive C Reactive Protein (Hs-CRP) in Mexican Healthy Population." Journal of Personalized Medicine 13, no. 5 (2023): 876. http://dx.doi.org/10.3390/jpm13050876.

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In the last decades, it has been shown that inflammatory processes play a role in the development of mental and physical problems; although some studies have researched the relationship between inflammation and psychological variables, the inclusion of biochemical variables as possible confounders has been limited. Therefore, the aim of this study was to determine whether psychological variables are associated with the inflammatory marker, highly sensitive CRP (hs-CRP), after controlling for personal and biochemical variables in the Mexican population. The study was performed at the University
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Florêncio, Glauber Pimentel, Analicy Rodrigues Xavier, Ana Catarina de Castro Natal, et al. "Synergistic Effects of Probiotics and Lifestyle Interventions on Intestinal Microbiota Composition and Clinical Outcomes in Obese Adults." Metabolites 15, no. 2 (2025): 70. https://doi.org/10.3390/metabo15020070.

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Background and objective: Obesity is a growing global epidemic. The composition of the intestinal microbiota can be influenced by several factors. Studies highlight the role of intestinal bacteria in the pathophysiology of obesity. So, the objective of this study was to investigate whether the use of probiotics, together with healthy lifestyle habits, contributes to weight reduction in obese individuals by analyzing the intestinal microbiota profile. Methods: A prospective study was carried out with 45 adults with obesity. Participants underwent guidance on healthy lifestyle habits, received a
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Korkmaz, Sevda, Bilal Üstündağ, Ömer Özer, et al. "Copeptin levels and blood lipid profile in borderline patients with or without self-mutilation." South African Journal of Psychiatry 22, no. 1 (2016): 5. http://dx.doi.org/10.4102/sajpsychiatry.v22i1.976.

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<p><strong>Purpose:</strong> Self-mutilation, known as self-harming behaviour of an individual without the intention of suicide, is commonly observed in individuals with borderline personality disorder. The objective of this study is to compare copeptin levels that are known to be related to aggressive behaviour and blood lipid profiles in borderline patients with and without self-mutilation.</p><p><strong>Methods:</strong> Twenty patients with self-mutilation [SM(+)] and 20 patients without self-mutilation [SM(−)] between the ages of 18 and 49, diagno
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Saha, Sumanta Kumer, S. Chakrabarty, Tamanna Tabassum Moni, Md Rezaul Kadir, Aliva Haque, and Sabiha Tabassum Mithila. "“Study of Psychosocial Antecedents to Precipitation of Congestive Heart Failure in Cardiac Patients: A Prospective Observational Study”." Saudi Journal of Medical and Pharmaceutical Sciences 9, no. 05 (2023): 275–81. http://dx.doi.org/10.36348/sjmps.2023.v09i05.001.

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Introduction: Psychosocial factors, such as stress, adversity, socioeconomic status, depression, and anxiety, are associated with overall health and with cardiovascular health in particular. Psychosocial risk factors have been frequently studied in relation to coronary heart disease. In observational studies, high levels of depression and anxiety have consistently been associated with incident coronary heart disease, whereas associations with hostility and social support have been mixed. However, psychosocial factors have been examined less often in HF. Among patients with HF, depression is th
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Wicht, Corentin A., Camille F. Chavan, Jean-Marie Annoni, et al. "Predictors for Returning to Paid Work after Transient Ischemic Attack and Minor Ischemic Stroke." Journal of Personalized Medicine 12, no. 7 (2022): 1109. http://dx.doi.org/10.3390/jpm12071109.

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This study aims to determine which factors within the first week after a first-ever transient ischemic attack (TIA) or minor ischemic stroke (MIS) are associated with stroke survivors’ ability to return to either partial or full time paid external work (RTpW). In this single-center prospective cohort study, we recruited 88 patients with first-ever TIA or MIS (NIHSS ≤ 5). Bivariate analyses were conducted between patients that did (RTpW) or did not return to paid work (noRTpW) within 7 days after stroke onset and at 3-months follow-up. Then, we conducted multivariate logistic and negative binom
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Shipelin, Vladimir A., Nikita V. Trusov, Sergey A. Apryatin, et al. "Effects of Tyrosine and Tryptophan in Rats with Diet-Induced Obesity." International Journal of Molecular Sciences 22, no. 5 (2021): 2429. http://dx.doi.org/10.3390/ijms22052429.

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Amino acids tyrosine (Tyr) and tryptophan (Trp) play a significant role in the regulation of energy metabolism, locomotor activity, and eating behavior. We studied the possibility of modulating these processes in obesity by increasing the pool of Tyr and Trp in the experimental diet. As a model of obesity, we used Wistar rats fed a diet with an excess specific energy value (HFCD) for 64 days. Trp led to a normalization of the rats’ body weight almost to the control level, but increased anxiety-like behavior and decreased long-term memory. The consumption of amino acids resulted in increased gr
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Michelle, Ogidiagba Stephanie, Solomon Matthias Gamde, Bitty William, and Hauwa Kabir. "Effect of Diazepam on Thyroid Function Hormone and Associated Histological Markers." PHARMACOLOGY MEDICAL REPORTS ORTHOPEDIC AND ILLNESS DETAILS (COMORBID) 4, no. 1 (2025): 31–40. https://doi.org/10.55047/comorbid.v4i1.1628.

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Diazepam is widely used to manage anxiety and depression, but its effect on thyroid function remain poorly understood. This study aimed to explore the potential effects of diazepam on thyroid function hormones (T3, T4, and TSH), lipid profile, glucose, cortisol levels and thyroid gland histology in animal models. Twenty-four pre-pubertal rats (average weight 160g ± 20g) were divided into four groups, receiving diazepam at 15 mg/kg, 30 mg/kg, or 60 mg/kg daily for seven days, while a control group received standard feed and water ad libitum. General health, including body weight, food and water
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Tithi, Golder, Rani Mittra China, and Salamat Khandker Dr. "Knowledge on Risk Factors of Coronary Heart Diseases Among Diabetic PatientAttending at aTertiary Level Hospital in Bangladesh." International Journal of Medical Science and Clinical Research Studies 04, no. 10 (2024): 1720–24. https://doi.org/10.5281/zenodo.13880121.

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Background: Coronary Heart Disease (CHD) remains a leading cause of morbidity and mortality globally, with a significant impact on public health systems, especially in developing countries. Objective: This study aims to identify the knowledge of CHD risk factors amongdiabetic patients attending at a tertiary level hospital in Bangladesh. Methodology: A Cross Sectional Study conducted among the diabetic patients at Khulna Medical College Hospital, Khulna from January 2023 to April 2023. Total 150 known diabetic patients were selected by using simple random sampling method and face to face inter
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Selvi., C., and Dr.V.Duraisami. "Effects of Yogic Practices With and Without Diet Modification on Lipid Profile and Anxiety among Pregnant Women." October 9, 2017. https://doi.org/10.5281/zenodo.1005111.

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<em>The aim of this study is to examine the effects of yogic practices on lipid profiles (Triglycerides, HDL, LDL) and anxiety among pregnant women in their second trimester. To achieve the purpose sixty (60) primiparous women were randomly selected from various maternal health centers in and around Chennai city. Their age varied between 23 Years to 28 Years. Subjects were randomly assigned into three groups. Experimental group I (20-subjects) Experimental group II (20) and Control group (20). Experimental group I underwent six days of yogic practices for one hour in the morning between 6.30 a
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Shin, Seung-Ho, Sung Wan Byun, and Ho Yun Lee. "Analysis of Loudness Discomfort Level Tests in Tinnitus Patients." Audiology and Neurotology, March 1, 2024. http://dx.doi.org/10.1159/000538128.

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Introduction: We aimed to investigate the clinical significance of loudness discomfort level (LDL) test in tinnitus patients and its relationship with pure-tone audiometry, tinnitogram and questionnaires. Methods: We retrospectively reviewed the medical records of 320 tinnitus patients who visited a tertiary university hospital's tinnitus clinic and completed LDL tests between March 2020 and December 2022. Epidemiological data and psychoacoustic test results were collected. Results: LDL showed no significant differences between frequencies for both ears. Mean LDL did not correlate with mean pu
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